Venrock

Astronomer, Inc. is a company based in Cincinnati, Ohio, that specializes in developing a managed platform for data orchestration, primarily utilizing Apache Airflow. Established in 2014, Astronomer offers a comprehensive suite of products and services through its platform, known as Astro. This platform is designed to streamline the process of building, running, and monitoring data pipelines-as-code, catering to the needs of data engineers, scientists, and analysts. By providing tools for deploying, managing, and scaling data workflows, Astronomer enhances the availability of trusted data for organizations, making it easier for data teams to conduct business analytics effectively. As a commercial developer of Airflow, Astronomer plays a significant role in the data orchestration landscape, serving hundreds of thousands of teams globally.

Jade Biosciences is a biopharmaceutical company dedicated to developing innovative therapies for unmet needs in autoimmune diseases. Its lead asset, JADE-001, targets the APRIL pathway for treating IgA nephropathy, with initial clinical trials planned. Additionally, Jade has two preclinical antibody discovery programs, JADE-002 and JADE-003. The company was founded upon assets licensed from Paragon Therapeutics.

AIRNA is a biotechnology company specializing in the development of RNA editing therapies. Its platform enables the creation of therapeutics designed to treat both rare and common diseases, with the goal of improving patients' health.

Surrozen, Inc. is a clinical-stage biopharmaceutical company based in South San Francisco, California, focused on developing targeted regenerative antibodies to enhance tissue and organ repair in response to serious diseases. Founded in 2015, the company specializes in modulating the Wnt pathway, a crucial mediator of tissue regeneration, through its innovative antibody platforms that target specific organs and tissues. Notable programs include SZN-043, designed to stimulate liver regeneration in both acute and chronic liver diseases, and SZN-1326, aimed at repairing damaged epithelial tissue in patients with inflammatory bowel disease. Surrozen's approach extends to multiple organ systems, with potential applications in the intestine, liver, retina, cornea, lung, kidney, cochlea, skin, pancreas, and central nervous system.

Expedition Therapeutics operates as an unincorporated association.

Auditoria.AI, Inc. is a technology company based in Santa Clara, California, founded in 2019. It specializes in providing innovative financial solutions for enterprise accounting and audit, utilizing advanced artificial intelligence and machine learning technologies. The company focuses on enhancing compliance and automating finance back-office processes through its flagship product, which employs natural language processing and predictive analytics. By streamlining operations and reducing redundancy, Auditoria.AI aims to support finance teams in making informed, data-driven decisions and improving overall efficiency.

Solid Biosciences Inc. is a life science company focused on developing therapies for Duchenne muscular dystrophy (DMD), a genetic muscle-wasting disease primarily affecting boys. The company's lead product candidate, SGT-001, is a gene transfer therapy currently undergoing a Phase I/II clinical trial aimed at restoring functional dystrophin protein expression in patients' muscles. In addition to SGT-001, Solid Biosciences is advancing the Anti-LTBP4 program, which involves a monoclonal antibody designed to reduce fibrosis and inflammation by targeting the LTBP4 protein. The company also develops biomarkers and sensors, as well as the Solid Suit program, which focuses on creating wearable assistive devices with functional and therapeutic benefits. Founded in 2013 and headquartered in Cambridge, Massachusetts, Solid Biosciences has established a strategic collaboration with Ultragenyx to enhance gene therapy development for DMD. With no current cure for DMD, the company aims to provide innovative solutions for a condition that affects an estimated 10,000 to 15,000 cases in the United States.

Exceeds is a technology company that specializes in enhancing the productivity and performance of engineering teams. It offers a platform that leverages AI and data insights to capture daily work activities and feedback, identify skill gaps, and provide targeted support. This enables engineers to work more efficiently and effectively, without the need for micromanagement.

GenLogs is a technology company specializing in freight intelligence. It operates a platform that uses AI and a nationwide sensor network to monitor and analyze logistics operations and supply chains. The platform identifies reliable truck carriers based on specific equipment and lane requirements, tracks shipments, trailers, and equipment, and provides insights to enhance operational efficiency, reduce fraud risks, and support informed decision-making.

Oumi is a technology company that develops an open-source AI platform. This platform assists businesses in building, evaluating, and deploying advanced AI models at scale. It offers features like intelligent document processing, automated data extraction, and customizable workflows, helping businesses across industries enhance efficiency, reduce manual effort, and make data-driven decisions. The company is founded and operated by a team of academics and developers committed to promoting transparency and collaboration in frontier AI.

Timberlyne Therapeutics is a biopharmaceutical company focused on developing and commercializing innovative therapies for autoimmune diseases. It leverages its team's expertise in drug development to acquire promising assets targeting unmet medical needs. The company specializes in monoclonal antibodies with enhanced complement-dependent cytotoxicity, specifically targeting CD38, a protein highly expressed in various immune cells. This approach enables rapid and durable responses across a range of autoimmune diseases.

ADCendo ApS is a biotech company focused on the development of innovative anti-cancer therapies, specifically through the creation of antibody-drug conjugates (ADCs). These conjugates are designed to target receptors that are overexpressed in various forms of cancer, addressing significant unmet medical needs in the treatment landscape. ADCendo's approach aims to enhance targeted therapy for patients suffering from conditions such as soft-tissue sarcoma, osteosarcoma, glioblastoma multiforme, and triple-negative breast cancer, among others. By developing new medicines that effectively target carcinomas—including breast, colon, pancreatic, prostate, ovarian, and renal cancers—ADCendo seeks to improve treatment outcomes for cancer patients.

Cidara Therapeutics, Inc. is a biotechnology company based in San Diego, California, established in 2012. It specializes in the discovery, development, and commercialization of innovative anti-infective therapies aimed at treating serious diseases. The company's lead product candidate, rezafungin acetate, is an echinocandin-class antifungal designed to address serious invasive fungal infections such as candidemia and invasive candidiasis, which are associated with high mortality rates. Additionally, Cidara is advancing its Cloudbreak platform, which focuses on developing antiviral Fc-conjugates for the prevention and treatment of various viral infections, including influenza, RSV, HIV, and coronaviruses. Through its unique therapeutic approaches, Cidara Therapeutics aims to enhance treatment paradigms and improve patient outcomes in the face of life-threatening illnesses.

Metsera is a clinical-stage biopharmaceutical company dedicated to developing innovative therapies for obesity and metabolic conditions. The company focuses on advancing a variety of treatment options, including both oral and injectable therapies, specifically targeting incretin, non-incretin, and combination approaches. By integrating proprietary health technology tools, Metsera aims to provide personalized care that meets the evolving demands of weight loss treatment. Its commitment to addressing multiple therapeutic targets positions the company to significantly impact the future of obesity management and related metabolic diseases.

Crescent Biopharma is a biotechnology firm focused on developing novel precision-engineered medicines targeting verified biology to improve care for patients with solid tumors.

enGene, Inc. is a biotechnology company based in Vancouver, Canada, specializing in mucosal immunotherapy to address inflammatory bowel disease and diabetes. The company has developed a non-integrating biopolymer-based nucleotide delivery technology that enables the localized delivery of immune-modulating proteins to mucosal tissues, targeting conditions affecting the gastrointestinal tract, lung, and bladder. This innovative platform allows for the systemic release of proteins from the gut, which can be beneficial for treating a variety of immune disorders, as well as other conditions such as diabetes, anemia, and hemophilia. Founded in 1999, enGene has formed a strategic alliance with Takeda Pharmaceutical Company to further advance its therapeutic offerings.

Suki is a technology company that specializes in AI-driven voice solutions aimed at improving efficiency in healthcare documentation. Its flagship product, Suki Assistant, allows physicians to complete administrative tasks more quickly, alleviating the administrative burden on clinicians. The company utilizes advanced natural language processing and machine learning technologies to deliver a proprietary voice platform that offers high accuracy and a seamless voice experience. Through its innovative solutions, Suki seeks to transform the healthcare technology landscape into an invisible and supportive tool, enhancing the overall workflow for healthcare professionals.

Scope3 is a company focused on providing accurate supply chain emissions data to assist businesses in integrating sustainability into their decision-making processes. It operates a platform that models the essential inputs and outputs associated with products and services within the supply chain. By designing sustainable systems and generating monthly sustainability reports, Scope3 enables companies to adapt swiftly to external changes and receive recognition for their efforts in reducing carbon emissions. This approach positions Scope3 as a vital resource for organizations aiming to understand and mitigate their environmental impact effectively.

Candid Therapeutics is a biotechnology company specializing in the development of innovative therapies for immunological disorders. The company's primary focus is on creating novel, user-friendly treatments for autoimmune diseases. Their core technology involves advanced T-cell engager antibodies, which precisely redirect T-cells to selectively eliminate autoreactive B-cells, aiming to deliver transformative efficacy and improved therapeutic outcomes for patients.

Oruka Therapeutics is advancing innovative biologics to redefine patient care standards in chronic skin diseases.

Vanilla is an innovative Estate Advisory Platform designed to enhance the estate planning experience for wealth management firms. Built by estate professionals and advisors, the platform allows advisors, planners, and estate attorneys to provide comprehensive and modern estate planning services to their clients. By streamlining the estate analysis process, Vanilla addresses inefficiencies in document preparation and improves both advisors' and clients' understanding of estate matters. The platform aims to simplify the complexities of estate management, thereby enabling advisors to strengthen client relationships, attract new business, and deliver ongoing value through effective estate planning solutions.

Tenax Therapeutics, Inc. is a specialty pharmaceutical company dedicated to the identification, development, and commercialization of products aimed at addressing cardiovascular and pulmonary diseases with significant unmet medical needs. Headquartered in Morrisville, North Carolina, Tenax focuses on levosimendan, a pharmaceutical product designed to reduce morbidity and mortality in cardiac surgery patients at risk for low cardiac output syndrome. The company is also actively conducting a Phase 2 clinical trial to explore the efficacy of levosimendan in treating pulmonary hypertension associated with heart failure with preserved ejection fraction. Additionally, Tenax is involved in developing novel formulations of imatinib mesylate, a kinase inhibitor with the potential to serve as a disease-modifying therapy for pulmonary arterial hypertension. Founded in 1967, Tenax Therapeutics underscores its commitment to advancing treatments within these critical therapeutic areas.

Jade Biosciences is a biopharmaceutical company dedicated to developing innovative therapies for unmet needs in autoimmune diseases. Its lead asset, JADE-001, targets the APRIL pathway for treating IgA nephropathy, with initial clinical trials planned. Additionally, Jade has two preclinical antibody discovery programs, JADE-002 and JADE-003. The company was founded upon assets licensed from Paragon Therapeutics.

Element Biosciences, Inc., established in 2017 and headquartered in San Diego, California, specializes in developing innovative genetic analysis tools for research and diagnostic markets. The company's core business revolves around its disruptive DNA sequencing technology, which encompasses surface chemistry, sequencing chemistry, detection methods, and data analysis. Element Biosciences aims to enhance accessibility to next-generation sequencing by offering a modular, high-performing platform that delivers high-quality data and workflow flexibility, thereby reducing run and capital costs.

Tembo is a technology company that develops and manages scalable, secure platforms built on Postgres databases. Their platform enables developers to build, deploy, and manage various data services and applications efficiently, leveraging the extensive open-source Postgres ecosystem for common use cases. By productizing Postgres, Tembo reduces the need for specialized database management expertise, allowing clients to expand their database capabilities.

CASI Pharmaceuticals, Inc. is a U.S.-based biopharmaceutical company dedicated to developing and commercializing innovative therapeutics, particularly in the fields of hematology and oncology. The company focuses on addressing unmet medical needs by acquiring and launching products in China, the United States, and globally. CASI's product portfolio includes several therapeutics, such as EVOMELA, which is used as a conditioning treatment prior to autologous stem cell transplants for multiple myeloma patients, along with CID-103, CNCT19, MARQIBO, ZEVALIN, and ENMD-2076. The company's primary revenue driver is the sales of EVOMELA, as it executes its strategy to become a leading biopharmaceutical player by leveraging its expertise in regulatory and commercial operations within the China market.

Bright Peak Therapeutics is a biotechnology company focused on developing a range of immunotherapies aimed at treating cancer and autoimmune diseases. The company specializes in creating immuno-cytokines that possess pharmacological properties enabling tissue and cell-specific targeting of cytokine payloads. This innovative approach is designed to enhance the efficacy of treatments, ultimately improving patient outcomes and quality of life. By leveraging its expertise in cytokine therapeutics, Bright Peak aims to advance the field of immunotherapy and provide effective solutions for challenging medical conditions.

Lycia Therapeutics operates as a biotechnology company focused on discovering and developing first-in-class therapeutics using its proprietary Lysosomal Targeting Chimeras (LYTACs) platform. This platform enables the degradation of extracellular and membrane-bound proteins associated with challenging-to-treat diseases like cancer and autoimmune disorders, aiming to provide effective treatments for patients.

Averto Medical specializes in the manufacture of innovative medical devices designed to improve outcomes for patients with gastrointestinal diseases. Their primary product focuses on facilitating minimally invasive colorectal tumor removal, aiming to replace multiple surgical procedures and reduce associated complications.

Cullinan Therapeutics is a developer of an externally sourced cancer therapeutics intended to end a drug program quickly if the early research suggests it won't work. The company's therapeutics are developed via assets sourced internally through dry lab or externally through business, academic and pharma collaborations, enabling researchers to get a highly diversified portfolio of oncology therapeutics with a unique, cost-efficient business model.

Century Therapeutics, Inc. is a biotechnology company focused on developing innovative cell therapies derived from induced pluripotent stem cells (iPSCs) to treat hematologic and solid malignancies. Founded in 2018 and headquartered in Philadelphia, Pennsylvania, the company utilizes a specialized platform that integrates gene editing and protein engineering to create allogeneic therapies. This platform allows for the generation of master cell banks of modified immune effector cells, specifically engineered to optimize performance and reduce the risk of rejection by the host immune system. By employing advanced technologies such as CRISPR-mediated gene editing and proprietary chimeric antigen receptors, Century Therapeutics aims to address significant unmet medical needs in cancer and other diseases.

Archetype AI is a group of designers and technologists they are pioneering revolutionary artificial intelligence and interaction technologies for the real world.

Mirador Therapeutics specializes in developing precision medicine technologies to tackle immune-mediated inflammatory and fibrotic diseases. The company's core offering is a proprietary data analytics engine that integrates comprehensive patient molecular profiles, pinpoints novel therapeutic targets, and facilitates the creation of targeted diagnostics. This enables researchers and healthcare providers to tailor treatments to individual patients' genetics, potentially enhancing outcomes for those with chronic conditions.

Enliven Therapeutics is a clinical-stage precision oncology company based in Boulder, Colorado, focused on developing innovative small molecule therapies to enhance patient outcomes. Established in July 2019 by Sam Kintz, Joe Lyssikatos, and Anish Patel, the company employs a unique discovery process that leverages clinically validated biological targets alongside advanced chemistry. This methodology aims to overcome the limitations of current therapies by creating potentially first-in-class treatments that address critical challenges such as tolerability, combinability, resistance, and disease progression, particularly in cases involving brain metastases. Enliven's product pipeline includes ELVN-001, a selective small molecule kinase inhibitor targeting the BCR-ABL gene fusion in chronic myeloid leukemia, and ELVN-002, an irreversible HER2 inhibitor designed to penetrate the central nervous system and act against various HER2 variants.

Applied Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing innovative treatments for serious diseases that currently lack approved therapies. Established in 2016 and based in New York, the company is advancing a pipeline of novel product candidates that target high unmet medical needs, including cardiovascular diseases and metabolic disorders. Its lead candidate, AT-007, is in Phase I/II trials aimed at treating galactosemia. Additionally, AT-001 is undergoing Phase II trials for diabetic cardiomyopathy and Phase I trials for diabetic peripheral neuropathy, while AT-003 is in Phase I trials for diabetic retinopathy. The company also has preclinical candidates such as AT-104, intended for orphan hematological oncology conditions, demonstrating its commitment to addressing critical health challenges through targeted therapeutics.

Ocular Therapeutix, Inc. is a biopharmaceutical company focused on developing and commercializing innovative therapies for eye diseases using its proprietary bioresorbable hydrogel platform technology. The company markets ReSure Sealant, a hydrogel ophthalmic wound sealant designed to protect corneal incisions after cataract surgery. Its lead product candidate, DEXTENZA, is an ophthalmic insert that has completed Phase III clinical trials for post-surgical ocular pain, inflammation, and allergic conjunctivitis, and is also being investigated for dry eye diseases. Additionally, Ocular Therapeutix is developing several other products, including OTX-TP, an intracanalicular travoprost insert for glaucoma, and OTX-TKI, an intravitreal implant for wet age-related macular degeneration, among others. The company has established a strategic collaboration with Regeneron Pharmaceuticals to leverage its hydrogel technology in combination with Regeneron's VEGF-targeting compounds for retinal diseases. Founded in 2006 and headquartered in Bedford, Massachusetts, Ocular Therapeutix aims to address unmet needs in ophthalmology through its advanced therapeutic solutions.

enGene, Inc. is a biotechnology company based in Vancouver, Canada, specializing in mucosal immunotherapy to address inflammatory bowel disease and diabetes. The company has developed a non-integrating biopolymer-based nucleotide delivery technology that enables the localized delivery of immune-modulating proteins to mucosal tissues, targeting conditions affecting the gastrointestinal tract, lung, and bladder. This innovative platform allows for the systemic release of proteins from the gut, which can be beneficial for treating a variety of immune disorders, as well as other conditions such as diabetes, anemia, and hemophilia. Founded in 1999, enGene has formed a strategic alliance with Takeda Pharmaceutical Company to further advance its therapeutic offerings.

Cogent Biosciences is a biotechnology company dedicated to developing precision therapies for genetically defined diseases, aiming to treat the underlying causes and improve patient lives. The company employs proprietary T-cell engineering technology alongside tumor-targeting antibodies to harness the body's immune system against cancer. One of its key programs, CGT9486, is a selective tyrosine kinase inhibitor designed to inhibit specific mutations in KIT exon 17, which are associated with Systemic Mastocytosis and advanced gastrointestinal stromal tumors (GIST).

Tenaya Therapeutics is a preclinical stage biotechnology company based in South San Francisco, California, specializing in the development of innovative therapies for heart disease, particularly heart failure. Established in 2016, the company employs a multipronged approach to address the fundamental cellular pathologies associated with cardiac muscle disease. Tenaya Therapeutics advances its product candidates through three primary platforms: a cellular regeneration platform that reprograms cardiac fibroblasts into cardiomyocytes using proprietary transcription factors, a gene therapy platform for targeted delivery of therapeutic payloads to cardiac fibroblasts, and a precision medicine platform that offers personalized treatment strategies. Through its research, the company aims to enable physicians to regenerate heart tissue and tackle various forms of cardiomyopathies effectively.

Mineralys Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing innovative therapies for hypertension. The company is advancing its lead product candidate, MLS-101, a highly selective and potent aldosterone synthase inhibitor licensed from Mitsubishi Tanabe Pharma Corporation. Mineralys aims to provide a targeted treatment for patients with uncontrolled hypertension, particularly those who do not achieve adequate blood pressure control despite using multiple antihypertensive medications. By addressing the underlying factors associated with elevated aldosterone levels, Mineralys seeks to improve treatment outcomes for individuals suffering from this condition.

Adverum Biotechnologies is a clinical-stage gene therapy company focused on developing innovative treatments for ocular and rare diseases. Headquartered in Redwood City, California, the company aims to establish gene therapy as a new standard of care, aspiring to provide functional cures that restore vision and prevent blindness. Its pipeline includes several product candidates, notably ADVM-022, which targets wet age-related macular degeneration through a single intravitreal injection designed to deliver long-term therapeutic effects. Other candidates include ADVM-043 for alpha-1 antitrypsin deficiency and ADVM-053 for hereditary angioedema. Adverum collaborates with partners like Editas Medicine and Regeneron Pharmaceuticals to leverage advanced AAV vectors and develop treatments for various inherited retinal diseases and ocular therapeutic targets. Founded in 2006, the company was previously known as Avalanche Biotechnologies and rebranded in 2016.

Accompany Health is a health technology company dedicated to providing comprehensive in-home care to patients, particularly in underserved regions. The organization focuses on delivering primary care services, including chronic illness management and treatment for new symptoms. By facilitating the organization and coordination of care, Accompany Health aims to alleviate the common challenges faced by patients, such as long wait times and complex healthcare navigation. The company emphasizes building long-term relationships with the individuals they serve, ensuring that patients receive continuous support and care around the clock. Their approach prioritizes dignity and accessibility, catering especially to low-income patients with complex healthcare needs through both at-home and virtual care solutions.

Astria Therapeutics is a biopharmaceutical company based in Cambridge, Massachusetts, dedicated to developing innovative therapies for patients affected by rare allergic and immunological diseases. The company focuses on creating life-changing treatments, with its lead program, STAR-0215, being a monoclonal antibody designed to inhibit plasma kallikrein, currently in preclinical development for hereditary angioedema. Additionally, Astria is advancing STAR-0310, another monoclonal antibody, which targets the OX40 receptor and is also in preclinical development for atopic dermatitis, a condition characterized by impaired skin barrier function and significant itching. Through its targeted approach, Astria Therapeutics aims to address unmet medical needs in the field of immunology.

SmithRx is a San Francisco-based company that designs and manages customized pharmacy benefit plans for employers, aiming to enhance employee guidance and satisfaction. Founded in 2016, SmithRx operates on a modern technology platform that emphasizes transparency, efficiency, and data analytics. The company provides a cost-competitive pharmacy benefit management (PBM) model, featuring a pass-through pricing structure, a unified technology system, and high-quality service assurances. Its in-house team combines expertise from various healthcare and technology sectors, including experience from notable companies, to deliver exceptional support and clinical programs. SmithRx focuses on empowering its clients with maximum flexibility and control over their pharmacy benefits, ultimately helping to reduce drug spending and improve the management of prescription benefits. The company's name reflects its commitment to precision and craftsmanship in the pharmacy benefits industry.

Dianthus Therapeutics is a clinical-stage biotechnology company focused on developing innovative treatments for severe autoimmune diseases through targeted therapies. The company's lead candidate, DNTH103, is a monoclonal antibody designed to selectively inhibit a specific component of the immune system, offering potential advantages over existing complement therapies. This treatment aims to improve safety and efficacy for patients suffering from serious autoimmune and inflammatory conditions. Dianthus is committed to advancing its pipeline of next-generation complement therapeutics, supported by a team of experienced professionals in the biotech and pharmaceutical sectors. The company envisions that DNTH103 could be administered as a self-injection for certain patients, enhancing convenience and accessibility in treatment.

Zero Networks Inc. is a network security software developer founded in 2019 and headquartered in Tel Aviv, Israel. The company specializes in automating the definition, enforcement, and adaptation of network access policies for users and machines within an organization. Its cloud-based technology customizes access controls by learning how users and devices communicate, thereby enhancing security without the need for agents or complex policy configurations. Additionally, Zero Networks incorporates a two-factor authentication mechanism that allows legitimate but unusual connections through a secure wall on mobile devices. This approach ensures robust protection against potential breaches while maintaining operational continuity, making it an effective solution for organizations seeking to strengthen their network security posture.

Spyre Therapeutics is a biotechnology company focused on developing innovative antibody therapies aimed at transforming the treatment landscape for inflammatory bowel disease (IBD). By leveraging advanced antibody engineering, rational therapeutic combinations, and precision medicine strategies for patient selection, Spyre Therapeutics seeks to create next-generation products that address the chronic inflammation associated with IBD, which includes ulcerative colitis and Crohn's disease. The company aims to enhance existing treatment options, which currently include anti-inflammatory drugs, immunosuppressants, and biologics, thereby improving outcomes for patients suffering from these debilitating gastrointestinal disorders.

RefleXion Medical Inc. is a medical equipment company based in Hayward, California, focused on revolutionizing cancer treatment through its biologically-guided radiotherapy system (BgRT). This innovative technology allows tumors to continuously signal their location during treatment, enabling the simultaneous targeting of multiple tumors, even in cases of metastasized cancer. The RefleXion X1 machine is cleared for various forms of radiotherapy, including stereotactic body radiotherapy, stereotactic radiosurgery, and intensity-modulated radiotherapy. The BgRT system utilizes positron-emission tomography (PET) imaging data to synchronize tumor location information with the linear accelerator, allowing for real-time adjustments in treatment delivery with subsecond latency. RefleXion Medical has established strategic collaborations with Telix Pharmaceuticals Limited and HealthMyne Inc. since its incorporation in 2009.

MBrace Therapeutics is a privately held biopharmaceutical company focused on enhancing the quality of life for cancer patients. The company specializes in the development of antibody-drug conjugates (ADCs) targeting novel oncology targets. By utilizing innovative technology, MBrace Therapeutics creates anti-tumor monoclonal human recombinant antibodies that specifically target cancer cells. This approach allows for the precise delivery of toxic agents directly into the cancer cells, enabling healthcare professionals to more effectively treat various forms of cancer.

Scope3 is a company focused on providing accurate supply chain emissions data to assist businesses in integrating sustainability into their decision-making processes. It operates a platform that models the essential inputs and outputs associated with products and services within the supply chain. By designing sustainable systems and generating monthly sustainability reports, Scope3 enables companies to adapt swiftly to external changes and receive recognition for their efforts in reducing carbon emissions. This approach positions Scope3 as a vital resource for organizations aiming to understand and mitigate their environmental impact effectively.

Moment is a private markets liquidity provider that operates an institutional-grade platform designed for fixed-income investing. The company aims to deliver modern fixed-income solutions to a diverse range of financial entities, including global fintech companies, traditional brokerages, and registered investment advisors. By offering APIs, Moment enables its clients, which represent hundreds of billions in assets, to access and participate in modern financial markets more equitably and efficiently.

Taysha Gene Therapies, Inc. is a gene therapy company based in Dallas, Texas, focused on developing adeno-associated virus (AAV)-based therapies for monogenic diseases of the central nervous system (CNS). Founded in 2019, the company aims to create curative treatments for severe and life-threatening conditions. Its pipeline includes several product candidates, such as TSHA-101 for GM2 gangliosidosis, TSHA-118 for CLN1 disease, TSHA-102 for Rett syndrome, TSHA-103 for SLC6A1 haploinsufficiency disorder, and TSHA-104 for Surfeit locus 1 deficiency. Taysha collaborates with The University of Texas Southwestern Medical Center to enhance its development and commercialization efforts, leveraging expertise in gene therapy to advance its mission of eradicating monogenic CNS diseases.

ADARx Pharmaceuticals, Inc. is a clinical-stage biotechnology company based in San Diego, California, focused on the research and development of RNA editing therapeutics. Established in 2019, the company specializes in genetic medicine by utilizing a proprietary platform that employs endogenous enzymes, specifically adenosine deaminase acting on RNA (ADAR), to precisely target and correct single point mutations in RNA transcripts. This innovative approach aims to restore the production of functional proteins, offering potential treatments for a variety of diseases, including those affecting genetic, cardiometabolic, complement-mediated, and central nervous system areas. ADARx Pharmaceuticals is dedicated to developing life-saving therapeutics that address genetic mutations and provide solutions for conditions that are currently considered incurable.

Tisento Therapeutics, based in Massachusetts, specializes in developing innovative medicines to address diseases with substantial unmet medical needs. Its primary focus is on Mitochondrial Encephalomyopathy with Lactic Acidosis and Stroke (MELAS), a severe mitochondrial disorder. The company's therapies aim to treat mitochondrial diseases, both in the central nervous system and peripherally, by targeting key aspects of the disease's pathophysiology, including neuronal and mitochondrial function, cerebrovascular hemodynamics, and inflammatory processes. This approach enables patients to receive treatment promptly.

SQLite Cloud is a cloud-based service that offers an easy-to-use and highly scalable platform for managing SQLite databases in the cloud. Our product provides a secure and reliable way to store, manage, and share SQLite databases without requiring any server setup or maintenance. With our service, customers can easily create new databases, import existing databases, and collaborate with others on their projects. Our product also offers various features such as automated backups, point-in-time recovery, and real-time replication, which ensures high availability and data durability. Our goal is to make database management as easy and hassle-free as possible for our customers.

ORIC Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing innovative therapies to combat cancer by overcoming resistance mechanisms. The company's lead product candidate, ORIC-101, is a small molecule antagonist of the glucocorticoid receptor, which plays a significant role in resistance to various cancer treatments across multiple solid tumors. Another key candidate, ORIC-533, is an orally bioavailable inhibitor of CD73, targeting a critical pathway in the adenosine metabolism that contributes to resistance against chemotherapy and immunotherapy. Additionally, ORIC is working on a pipeline of precision medicines aimed at addressing other cancer resistance mechanisms. Founded in 2014 and headquartered in South San Francisco, California, ORIC Pharmaceuticals leverages the expertise of its scientific founders, who have extensive backgrounds in cancer research and target discovery.

Aledade, Inc. is a company that supports primary care physicians in establishing and managing accountable care organizations (ACOs) across the United States. Founded in 2014 and headquartered in Bethesda, Maryland, Aledade provides a comprehensive suite of services including data analytics, guided workflows, regulatory expertise, and payer relationships. The company aims to empower independent primary care providers by offering customized solutions, operational support, and advanced technology to enhance practice efficiency and patient care. Aledade serves a diverse range of healthcare practices, including small and large practices, community health centers, and multispecialty groups. By facilitating better care delivery and reducing overall costs, Aledade helps physicians maintain their independence while improving health outcomes for their patients.

NeoPhotonics is a technology company specializing in the development, manufacture, and sale of optical components and subsystems used in high-speed digital communications networks. The company offers a comprehensive range of active and passive optical products tailored for various market segments, including fiber-to-the-home (FTTH), data communications, storage area networks, and both metro and long-haul networks. Its product lineup includes transceivers, integrated splitters, multiplexers, and advanced optical modules, all designed to support a wide array of data rates and applications. Notably, NeoPhotonics is recognized for its innovative silica Planar Lightwave Circuit (PLC) technology, which plays a crucial role in modern optical networks. Additionally, the company produces MEMS-based Variable Optical Attenuators and Dynamic Channel Equalizers, enhancing the performance and efficiency of communication systems.

Pharvaris is a clinical-stage biopharmaceutical company dedicated to the discovery and development of oral therapies for rare diseases, specifically targeting hereditary angioedema (HAE) and other conditions mediated by bradykinin B2 receptors. The company aims to provide alternatives to injectable treatments through its novel small molecules. Pharvaris' lead drug candidate, PHA121, is a potent oral bradykinin B2 receptor antagonist currently undergoing Phase 1 clinical trials. The company's expertise stems from its co-founders, who include key figures involved in the development of icatibant, a well-established treatment for HAE. Pharvaris is committed to addressing significant unmet medical needs in the field of bradykinin-mediated diseases.

Upstream Bio Inc is a clinical-stage biotechnology company dedicated to developing treatments for inflammatory diseases, particularly severe respiratory disorders. The company's primary focus is on verekitug, an antibody therapy designed to inhibit the Thymic Stromal Lymphopoietin receptor. This receptor is a key target in the inflammatory response, influencing various immune cells and signaling pathways involved in both common and rare illnesses. By targeting TSLP, Upstream Bio aims to address the underlying mechanisms of severe asthma and related conditions, positioning itself as a significant player in the field of immunotherapy.

Lyra Therapeutics, Inc. is a clinical-stage therapeutics company dedicated to developing and commercializing innovative drug and delivery solutions for the localized treatment of ear, nose, and throat diseases. The company utilizes its proprietary XTreo technology platform, which allows for the precise and sustained delivery of medications directly to affected tissues through a single administration. Its lead product candidates, LYR-210 and LYR-220, are bioresorbable polymeric matrices designed for non-invasive in-office procedures, providing up to six months of continuous drug therapy for chronic rhinosinusitis. The active ingredient in these products is mometasone furoate, known for its established efficacy and safety profile in various FDA-approved medications. Founded in 2005 and headquartered in Watertown, Massachusetts, Lyra Therapeutics aims to improve treatment outcomes for patients suffering from ENT diseases.

Carmot Therapeutics, Inc. is a clinical-stage biotechnology company based in Berkeley, California, with an additional office in San Francisco. Founded in 2008, it focuses on discovering and developing innovative therapies for patients with metabolic diseases, including obesity and diabetes. Utilizing its proprietary Chemotype Evolution technology, Carmot Therapeutics aims to address the underlying causes of these conditions and accelerate the discovery of effective treatments. The company’s portfolio includes several clinical-stage drug candidates, such as CT-388 and CT-996, which are designed as GLP-1 receptor agonists for the treatment of obesity and type 2 diabetes, and CT-868, intended for type 1 diabetes patients who are overweight or obese. Through these efforts, Carmot Therapeutics seeks to create life-changing therapeutics that improve the health outcomes of individuals affected by metabolic diseases.

Vocera Communications, Inc. specializes in providing secure and integrated communication and workflow solutions tailored for mobile workers across various sectors, including healthcare, hospitality, retail, energy, and education. The company’s offerings enhance communication and operational efficiency by integrating with existing clinical systems, such as electronic health records and nurse call systems. Vocera's product suite includes the Vocera Communication and Workflow System, which connects various communication devices, including hands-free and voice-controlled options, and the Vocera Care Experience software, designed to improve patient care quality and streamline manual tasks. Additionally, Vocera operates the Experience Innovation Network, collaborating with healthcare organizations to develop innovative solutions that improve patient and care team experiences. The company, founded in 2000 and headquartered in San Jose, California, serves approximately 1,700 healthcare facilities globally, including hospitals and clinics, and distributes its products through direct sales, resellers, and distributors.

Airspeed is a developer of team-building software designed to enhance digital connections within modern companies. Its platform offers a suite of applications that provide engaging solutions for celebrating employee milestones, recognizing colleagues, and fostering connections among hybrid and remote teams. By serving as a system of record for company culture, Airspeed helps organizations cultivate a strong environment of engagement, recognition, and collaboration, ultimately improving employee retention and productivity.

Applied Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing innovative treatments for serious diseases that currently lack approved therapies. Established in 2016 and based in New York, the company is advancing a pipeline of novel product candidates that target high unmet medical needs, including cardiovascular diseases and metabolic disorders. Its lead candidate, AT-007, is in Phase I/II trials aimed at treating galactosemia. Additionally, AT-001 is undergoing Phase II trials for diabetic cardiomyopathy and Phase I trials for diabetic peripheral neuropathy, while AT-003 is in Phase I trials for diabetic retinopathy. The company also has preclinical candidates such as AT-104, intended for orphan hematological oncology conditions, demonstrating its commitment to addressing critical health challenges through targeted therapeutics.

Tembo is a technology company that develops and manages scalable, secure platforms built on Postgres databases. Their platform enables developers to build, deploy, and manage various data services and applications efficiently, leveraging the extensive open-source Postgres ecosystem for common use cases. By productizing Postgres, Tembo reduces the need for specialized database management expertise, allowing clients to expand their database capabilities.

Abivax is a clinical-stage biotechnology company based in France, dedicated to developing innovative therapeutics that leverage the body's natural immune mechanisms to treat patients with autoimmune diseases, viral infections, and cancer. The company's primary focus is on chronic inflammatory diseases, particularly inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. Abivax is currently evaluating its leading drug candidate, obefazimod, in Phase 3 clinical trials aimed at addressing moderately to severely active ulcerative colitis. Through its drug development platforms, Abivax strives to deliver novel and effective treatments to patients with significant unmet medical needs in these therapeutic areas.

Apogee Therapeutics is a San Francisco-based biotechnology company founded in 2022, specializing in the development of novel therapies for immunological and inflammatory disorders. The company focuses on creating differentiated biologics to treat conditions such as atopic dermatitis and chronic obstructive pulmonary disease, addressing significant unmet medical needs. Apogee's approach involves advancing antibody programs designed to target established mechanisms of action while utilizing advanced engineering techniques to enhance the therapeutic properties, including extended half-life. The company is actively developing two main programs: APG777 for atopic dermatitis and APG808 for chronic obstructive pulmonary disease.

VectivBio AG is a clinical-stage biotechnology company based in Basel, Switzerland, founded in 2019 as a spinout from Therachon. The company specializes in the discovery, development, and commercialization of innovative treatments for severe rare diseases, particularly those with significant unmet medical needs. Its lead product candidate, Apraglutide, is a synthetic GLP-2 analog designed to enhance the intestine’s ability to absorb fluids and nutrients, thereby reducing the reliance on parenteral support in patients with short bowel syndrome. VectivBio is dedicated to developing best-in-disease therapies that aim to meaningfully improve the lives of patients and their families, providing more than just incremental advancements over existing standard-of-care options.

Abivax is a clinical-stage biotechnology company based in France, dedicated to developing innovative therapeutics that leverage the body's natural immune mechanisms to treat patients with autoimmune diseases, viral infections, and cancer. The company's primary focus is on chronic inflammatory diseases, particularly inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. Abivax is currently evaluating its leading drug candidate, obefazimod, in Phase 3 clinical trials aimed at addressing moderately to severely active ulcerative colitis. Through its drug development platforms, Abivax strives to deliver novel and effective treatments to patients with significant unmet medical needs in these therapeutic areas.

Terns Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing molecularly targeted, oral, small-molecule drugs aimed at treating cancer and liver diseases. Founded in 2017 and headquartered in Foster City, California, with additional offices in Shanghai, the company is advancing a pipeline of therapeutics, including TERN-101, a potent non-bile acid farnesoid X receptor agonist, and TERN-201, a semicarbazide-sensitive amine oxidase inhibitor. Terns leverages its expertise in disease biology and medicinal chemistry, along with a cost-effective drug discovery model and robust clinical development capabilities, to create innovative therapies that address significant unmet medical needs both in China and globally.

Nightfall is a cloud data protection platform that employs machine learning to identify and manage business-critical data across various applications. The company offers a comprehensive Software as a Service (SaaS) solution that seamlessly integrates with existing SaaS applications, APIs, and data infrastructures. Nightfall's platform automatically classifies sensitive data, ensuring that critical information is not overlooked. Additionally, it provides automated workflows for quarantining, deleting, and alerting users about data exposure and hygiene issues, all without impacting end-user experience. With its Nightfall Developer Platform, the company allows developers to incorporate its data classification and protection capabilities into their applications through a set of cloud-hosted APIs and SDKs, enhancing operational efficiency and security for users.

Dgraph Labs, Inc. is a San Francisco-based company that develops and operates a fast, transactional, and distributed graph database designed to efficiently manage and retrieve structured data. Founded in 2016, Dgraph offers a low-latency solution that supports real-time user queries, catering to a diverse clientele from small startups to large enterprises. Its flagship product, Slash Enterprise, is a fully-managed, serverless solution optimized for handling terabytes of data in production environments. This service is deployed on dedicated, multi-zone clusters across major cloud platforms such as AWS, Azure, and GCP. Dgraph's technology also addresses various use cases, including semantic search, pattern matching, and fraud detection, enabling clients to effectively manage, represent, and visualize large datasets.

Annexon Biosciences is a clinical-stage biopharmaceutical company focused on developing novel therapies for patients with classical complement-mediated disorders affecting the body, brain, and eye. The company's pipeline is built on a platform technology that targets well-researched autoimmune and neurodegenerative disease processes triggered by the aberrant activation of C1q, the initiating molecule of the classical complement pathway. Annexon's lead product candidate, ANX005, is a full-length monoclonal antibody designed for intravenous administration to treat autoimmune and neurodegenerative disorders. Another key candidate, ANX007, is a monoclonal antibody Fab formulated for intravitreal administration to address neurodegenerative ophthalmic disorders. The company employs a biomarker-driven development strategy to ensure that its product candidates effectively engage the target at therapeutic doses within the intended patient tissue, while also exploring additional orphan and large market indications.

DBV Technologies S.A. is a clinical-stage biopharmaceutical company headquartered in Montrouge, France, focused on developing innovative treatments for food allergies through epicutaneous immunotherapy. The company's lead candidate, Viaskin Peanut, has completed Phase III clinical trials for the treatment of peanut allergies in children, adolescents, and adults. Additionally, DBV Technologies is advancing Viaskin Milk, which is in Phase I/II trials for cow’s milk protein allergy and related conditions, and Viaskin Egg, currently in pre-clinical development for hen’s egg allergy. The company is also exploring a booster vaccine for Bordetella pertussis and has ongoing research programs targeting respiratory syncytial virus, Crohn’s disease, celiac disease, and type I diabetes. Notably, DBV Technologies collaborates with Nestlé Health Science to develop MAG1C, an atopy patch test aimed at diagnosing non-IgE mediated cow’s milk protein allergy in infants and toddlers. Founded by pediatricians and entrepreneurs in 2002, DBV Technologies aims to revolutionize the field of immunotherapy by safely activating the immune system through its proprietary Viaskin technology.

Meltano is an open-source DataOps platform that integrates various leading open-source tools for managing the data lifecycle. It incorporates the Singer standard for data integration, featuring a library of over 200 connectors, as well as tools like dbt for data transformation, Airflow for orchestration, and plans to include Superset for data visualization. Meltano aims to simplify the processes of configuration, deployment, and monitoring while allowing data teams to adopt practices such as version control and continuous integration/continuous deployment. The platform collaborates with a community of over 1,200 professionals from startups, global enterprises, and consultancies to advance data infrastructure. Thousands of active projects utilizing Meltano are presently in operation across various organizations, demonstrating its practical application and adaptability in the data management landscape.

Moment is a private markets liquidity provider that operates an institutional-grade platform designed for fixed-income investing. The company aims to deliver modern fixed-income solutions to a diverse range of financial entities, including global fintech companies, traditional brokerages, and registered investment advisors. By offering APIs, Moment enables its clients, which represent hundreds of billions in assets, to access and participate in modern financial markets more equitably and efficiently.

Celcuity Inc. is a clinical-stage biotechnology company based in Minneapolis, Minnesota, focusing on cancer diagnosis and treatment. The company utilizes its CELsignia diagnostic platform, which analyzes living tumor cells to identify specific cellular processes that drive individual cancers. This innovative approach enables the discovery of new cancer sub-types that traditional molecular diagnostics may miss. Celcuity is developing diagnostic tests, including the CELsignia HSF test for HER2-negative breast cancer and the CELsignia MP test for various cancers, such as breast, lung, colon, ovarian, kidney, and bladder. By translating these discoveries into companion diagnostics, Celcuity aims to enhance therapeutic options for cancer patients and improve treatment outcomes, while also aiding pharmaceutical companies in defining targeted therapy patient populations more accurately. Founded in 2011, Celcuity is committed to advancing oncology through precise diagnostic and therapeutic innovations.

The Public Health Company is a pioneering firm that specializes in biosecurity solutions, offering a SaaS-enabled platform designed for the management of bio-risks. Founded in 2020 and headquartered in Palo Alto, California, the company leverages advanced technology and expert knowledge to address the challenges of enterprise risk management. Its platform focuses on identifying and mitigating physical world threats across various applications, providing clients with actionable and predictive intelligence. This enables organizations to implement dynamic risk management strategies efficiently and effectively, enhancing their preparedness against potential biohazards.

Kelonia Therapeutics is developing a new wave of genetic medicines using its next-generation vivo gene delivery platform. The company's cutting-edge in vivo gene delivery technology is simple and elegant, relying on a few potent lentiviral vector-like particles to precisely and efficiently deliver genetic cargo to the desired target tissue, and only that tissue, every time. To deliver genetic cargo only to the desired tissue, the lentiviral vector gene delivery platform employs a simple and elegant solution based on decades of research, development, and technical experience. Kelonia's mission is to develop a new wave of accessible genetic medicines that will transform the lives of patients suffering from a broad range of conditions.

Vanilla is an innovative Estate Advisory Platform designed to enhance the estate planning experience for wealth management firms. Built by estate professionals and advisors, the platform allows advisors, planners, and estate attorneys to provide comprehensive and modern estate planning services to their clients. By streamlining the estate analysis process, Vanilla addresses inefficiencies in document preparation and improves both advisors' and clients' understanding of estate matters. The platform aims to simplify the complexities of estate management, thereby enabling advisors to strengthen client relationships, attract new business, and deliver ongoing value through effective estate planning solutions.

Dianthus Therapeutics is a clinical-stage biotechnology company focused on developing innovative treatments for severe autoimmune diseases through targeted therapies. The company's lead candidate, DNTH103, is a monoclonal antibody designed to selectively inhibit a specific component of the immune system, offering potential advantages over existing complement therapies. This treatment aims to improve safety and efficacy for patients suffering from serious autoimmune and inflammatory conditions. Dianthus is committed to advancing its pipeline of next-generation complement therapeutics, supported by a team of experienced professionals in the biotech and pharmaceutical sectors. The company envisions that DNTH103 could be administered as a self-injection for certain patients, enhancing convenience and accessibility in treatment.

Quiq, Inc. is a technology company based in Bozeman, Montana, founded in 2015. It specializes in developing customer service messaging management software that enhances communication between businesses and their customers. Quiq offers a cloud-based platform that allows consumers to interact with brands through various digital messaging channels, including SMS, web chat, and social messaging apps. The company's flagship product, Quiq IQ, enables the creation and deployment of AI-driven bots to assist customer service agents in managing inquiries efficiently. Quiq's solutions are designed to provide personalized and proactive customer support at scale, facilitating seamless transitions from AI to human agents. With a focus on customer experience and advanced automation capabilities, Quiq serves notable clients such as Volvo and IHG Hotels & Resorts, helping them implement effective AI strategies to improve customer engagement. In March 2017, the company rebranded from Centricient Inc. to its current name, Quiq, reflecting its commitment to innovative customer interaction solutions.

Lyra Therapeutics, Inc. is a clinical-stage therapeutics company dedicated to developing and commercializing innovative drug and delivery solutions for the localized treatment of ear, nose, and throat diseases. The company utilizes its proprietary XTreo technology platform, which allows for the precise and sustained delivery of medications directly to affected tissues through a single administration. Its lead product candidates, LYR-210 and LYR-220, are bioresorbable polymeric matrices designed for non-invasive in-office procedures, providing up to six months of continuous drug therapy for chronic rhinosinusitis. The active ingredient in these products is mometasone furoate, known for its established efficacy and safety profile in various FDA-approved medications. Founded in 2005 and headquartered in Watertown, Massachusetts, Lyra Therapeutics aims to improve treatment outcomes for patients suffering from ENT diseases.

Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in New Haven, Connecticut, established in 2011. The company specializes in the development and commercialization of Haduvio, an oral extended-release formulation of nalbuphine. Haduvio is currently undergoing a Phase IIb/III clinical trial, known as the PRISM trial, aimed at treating chronic pruritus associated with prurigo nodularis. Additionally, Trevi is exploring the use of nalbuphine ER for other serious neurologically mediated conditions, including chronic cough in patients with idiopathic pulmonary fibrosis and levodopa-induced dyskinesia in individuals with Parkinson’s disease. The treatment targets conditions that share a common pathophysiology mediated through opioid receptors in the central and peripheral nervous systems.

Ocelot Bio brings new treatment options to patients with severe liver disease. It researches and discovers medicines that help in the treatment of hepatorenal syndrome, a complication of severe liver disease.

Astronomer, Inc. is a company based in Cincinnati, Ohio, that specializes in developing a managed platform for data orchestration, primarily utilizing Apache Airflow. Established in 2014, Astronomer offers a comprehensive suite of products and services through its platform, known as Astro. This platform is designed to streamline the process of building, running, and monitoring data pipelines-as-code, catering to the needs of data engineers, scientists, and analysts. By providing tools for deploying, managing, and scaling data workflows, Astronomer enhances the availability of trusted data for organizations, making it easier for data teams to conduct business analytics effectively. As a commercial developer of Airflow, Astronomer plays a significant role in the data orchestration landscape, serving hundreds of thousands of teams globally.

SmithRx is a San Francisco-based company that designs and manages customized pharmacy benefit plans for employers, aiming to enhance employee guidance and satisfaction. Founded in 2016, SmithRx operates on a modern technology platform that emphasizes transparency, efficiency, and data analytics. The company provides a cost-competitive pharmacy benefit management (PBM) model, featuring a pass-through pricing structure, a unified technology system, and high-quality service assurances. Its in-house team combines expertise from various healthcare and technology sectors, including experience from notable companies, to deliver exceptional support and clinical programs. SmithRx focuses on empowering its clients with maximum flexibility and control over their pharmacy benefits, ultimately helping to reduce drug spending and improve the management of prescription benefits. The company's name reflects its commitment to precision and craftsmanship in the pharmacy benefits industry.

RefleXion Medical Inc. is a medical equipment company based in Hayward, California, focused on revolutionizing cancer treatment through its biologically-guided radiotherapy system (BgRT). This innovative technology allows tumors to continuously signal their location during treatment, enabling the simultaneous targeting of multiple tumors, even in cases of metastasized cancer. The RefleXion X1 machine is cleared for various forms of radiotherapy, including stereotactic body radiotherapy, stereotactic radiosurgery, and intensity-modulated radiotherapy. The BgRT system utilizes positron-emission tomography (PET) imaging data to synchronize tumor location information with the linear accelerator, allowing for real-time adjustments in treatment delivery with subsecond latency. RefleXion Medical has established strategic collaborations with Telix Pharmaceuticals Limited and HealthMyne Inc. since its incorporation in 2009.

Astrix Security specializes in safeguarding non-human identities, such as API keys, service accounts, and access tokens, by extending identity security to machines. Its cloud-based platform provides organizations with comprehensive visibility into these non-human identities, along with automated risk assessment and remediation capabilities. By managing the lifecycle of non-human identities, Astrix helps organizations mitigate excessive, unnecessary, and harmful access, thereby reducing the risk of service supply chain attacks and data breaches. The platform is designed to enable secure app-to-app integration and automation, allowing organizations to harness technology without compromising security.

Zero Networks Inc. is a network security software developer founded in 2019 and headquartered in Tel Aviv, Israel. The company specializes in automating the definition, enforcement, and adaptation of network access policies for users and machines within an organization. Its cloud-based technology customizes access controls by learning how users and devices communicate, thereby enhancing security without the need for agents or complex policy configurations. Additionally, Zero Networks incorporates a two-factor authentication mechanism that allows legitimate but unusual connections through a secure wall on mobile devices. This approach ensures robust protection against potential breaches while maintaining operational continuity, making it an effective solution for organizations seeking to strengthen their network security posture.

Decodable is a serverless data integration and engineering platform focused on streaming data, founded in 2021 by Eric Sammer and headquartered in San Francisco, California. The company offers a software solution that enables applications and data engineers to construct complex data pipelines efficiently. Its platform facilitates seamless connections to various existing messaging, storage, and database systems, allowing users to rapidly collect, process, and deliver data to both offline and online systems. Through its innovative approach, Decodable aims to simplify the management of streaming data, enhancing the capabilities of organizations in handling real-time data flows.

3Box Labs is a technology company based in New York that specializes in decentralized identity and data management solutions for web3 applications. Founded in 2018, it offers a suite of products including 3box.io, a social profiles application tailored for Ethereum users, and 3box.js, an API that facilitates user onboarding and data management for developers. Additionally, 3Box provides the 3box-dapp, which enables users to create and manage their social profiles, interact with decentralized applications, build reputations, and securely store data. The company's platform is designed to enhance user experience by ensuring that applications are lighter, more trustworthy, and carry reduced data management liabilities, thereby fostering a sustainable ecosystem where users have greater control over their data.

Running Tide is a global ocean health company that focuses on deploying nature-based interventions to remove carbon from the atmosphere and combat ocean acidification. The company utilizes adaptive aquaculture techniques to optimize marine environments while producing healthy, low-carbon protein. Running Tide employs advanced monitoring and measurement technology, leveraging photosynthesis, ocean currents, and gravity to store carbon in the deep ocean. By analyzing ocean data, the company aims to enhance the utilization of two-thirds of the Earth’s surface in the fight against climate change, ultimately improving the health of the world's oceans.

Atom Computing Inc. is a technology company based in Berkeley, California, focused on the development of scalable quantum computers utilizing individual atoms. Founded in 2018, the company leverages the quantum mechanical properties of these atoms to process information and tackle complex problems that are beyond the capabilities of traditional computing. Atom Computing's innovative approach enables precise control, scaling, and stabilization of atoms, allowing quantum engineers and researchers to conduct advanced calculations in various fields, including drug design, computational chemistry, and other areas of general computing.

Apogee Therapeutics is a San Francisco-based biotechnology company founded in 2022, specializing in the development of novel therapies for immunological and inflammatory disorders. The company focuses on creating differentiated biologics to treat conditions such as atopic dermatitis and chronic obstructive pulmonary disease, addressing significant unmet medical needs. Apogee's approach involves advancing antibody programs designed to target established mechanisms of action while utilizing advanced engineering techniques to enhance the therapeutic properties, including extended half-life. The company is actively developing two main programs: APG777 for atopic dermatitis and APG808 for chronic obstructive pulmonary disease.

Mythic Therapeutics is a biotechnology company dedicated to advancing cancer treatments through innovative therapies. The company specializes in the development of antibody-drug conjugates (ADCs), utilizing a unique protein engineering approach that enhances the effectiveness of these targeted therapies. Mythic Therapeutics' technology significantly improves the uptake of therapeutic agents in cancerous cells while minimizing their release in healthy cells, thereby increasing efficacy across various cancer types. This method not only boosts the potency of the treatments but also ensures a favorable safety profile, enabling healthcare providers to harness the full potential of ADCs. As such, Mythic Therapeutics aims to make a meaningful impact on cancer care by addressing a broad spectrum of tumor targets.

Suki is a technology company that specializes in AI-driven voice solutions aimed at improving efficiency in healthcare documentation. Its flagship product, Suki Assistant, allows physicians to complete administrative tasks more quickly, alleviating the administrative burden on clinicians. The company utilizes advanced natural language processing and machine learning technologies to deliver a proprietary voice platform that offers high accuracy and a seamless voice experience. Through its innovative solutions, Suki seeks to transform the healthcare technology landscape into an invisible and supportive tool, enhancing the overall workflow for healthcare professionals.

Ablaze Pharmaceuticals is a clinical-stage biopharmaceutical company dedicated to developing Targeted Radiotherapy (TRT) treatments aimed at benefiting cancer patients. The company focuses on innovative TRT products, utilizing the extensive business experience and networks of its founders in cross-border product development and deal-making. By targeting the Chinese market, Ablaze Pharmaceuticals seeks to provide effective cancer treatment options tailored to the needs of patients in the region.