Service Provider Capital is a venture capital firm established in 2014 and based in Colorado. The firm focuses on early-stage investments, notably seed-stage opportunities, and participates as a co-investor in Series A rounds led by institutional venture funds. Its portfolio interests span a broad range of technology sectors, including artificial intelligence, machine learning, blockchain, cybersecurity, e-commerce, education technology, fintech, hardware, information technology, robotics, health, and cannabis.

Founded in 2007, Foundry Group is a venture capital firm headquartered in Boulder, Colorado. It focuses on early-stage investments in information technology, Internet, and software companies across North America.

Founded in 1999, Access Venture Partners is a venture capital firm based in Denver, Colorado. It specializes in seed and early-stage investments in technology companies across the United States, with a focus on software, cybersecurity, big data, clean technology, SaaS, and new media sectors. The firm typically invests between $0.25 million to $2.5 million per company, seeking to take its portfolio companies public within two to four years.

Boomtown Accelerator, established in 2014 and based in Boulder, Colorado, is a startup accelerator that invests in early-stage companies, primarily in the advertising technology, internet, mobile, and healthcare technology sectors. It offers a 12-week program, providing selected teams with $20,000 in seed money, access to office space and amenities, and strategic support from partners and staff. The accelerator also connects startups with expert mentors, alumni network, and potential corporate customers and funding sources. Boomtown's approach is tailored to each company's needs, aiming to help startups transform ideas into profitable, scalable businesses.

FirstMile Ventures is a venture capital firm specializing in seed and early-stage investments, primarily focusing on B2B software and infrastructure technology companies. Based in Colorado Springs with an additional office in Denver, the firm invests across North America but prefers Colorado-based opportunities. Initial investments typically range from $0.05 million to $1.5 million, with provisions for follow-on financing.

Founded in 2013, Matchstick Ventures is a venture capital firm based in Minneapolis, Minnesota. It supports the creation and growth of early-stage technology companies, primarily focusing on seed-stage investments across various sectors such as business products, services, information technology, and TMT.

Boulder Ventures is a venture capital firm based in Boulder, Colorado, founded in 1995. It focuses on early-stage information technology and life sciences companies, investing in areas such as communications software and services, network infrastructure, information management, and biotechnology tools including drug discovery. The firm targets opportunities in Colorado and the Mid-Atlantic region and typically participates in initial investments with potential follow-on capital, often aiming to lead deals in its portfolio companies.

Right Side Capital Management is a San Francisco-based venture capital firm that focuses on early-stage, pre-seed technology startups in underserved segments of the ecosystem. It invests in a high-volume, capital-efficient portfolio, typically funding rounds of 50,000 to 500,000 and making roughly 75 to 100 investments per year. The firm targets opportunities across the United States and internationally, including Canada, Israel, Australia, New Zealand, and Western Europe, prioritizing companies with scalable products and prudent capital use outside major metro hubs. Since its inception, it has built a broad portfolio across many states. It commits to a fast decision process, often delivering a yes or no within two weeks to help founders establish momentum.

New Enterprise Associates is a venture capital firm founded in 1977 and based in Menlo Park, California, with offices in the United States, India and China. It makes investments across technology and healthcare startups at multiple stages, from seed to growth, including software, cloud, data, internet services, fintech, AI, e-commerce, and enterprise technology, as well as healthcare information technology, life sciences, medical devices, and biopharma. It also considers energy technology and infrastructure opportunities, such as solar, batteries and smart grids. The firm pursues a global approach, with activity in the United States, Asia and other regions, and supports companies through rounds of financing ranging from small to sizable investments as they scale. NEA focuses on building portfolios in software, IT services, consumer technology, and healthcare technology, backing ambitious entrepreneurs across sectors and geographies.

Alumni Ventures Group is a venture capital firm based in Manchester, New Hampshire, with offices across North America. It provides access to venture investing for individual accredited investors, particularly alumni networks, by offering diversified portfolios of venture opportunities and allowing members to invest alongside fellow alumni in ventures led by peers. The firm backs early-stage and later-stage opportunities across technology, consumer, healthcare, financial services, and other sectors, with a sector- and geography-agnostic approach. It typically invests between $10,000 and $3 million per deal and emphasizes the involvement of alumni connections and an institutional lead investor in opportunities. Alumni Ventures also offers focused funds to broaden participation, enabling accredited investors to access venture portfolios diversified by type, sector, stage, and geography. The model aims to democratize access to venture capital while maintaining rigorous selection standards through alumni networks.

Founded in 2005, Iron Gate Capital is a venture capital firm based in Louisville, Colorado. It primarily invests in enterprise technology companies at the early growth stage, with initial investments ranging from $3 to $5 million.

Greenline Ventures is a Denver-based investment firm that operates across capital markets and financial services in the United States. The firm engages in asset management and targets buyout investments within the financial services sector, with a focus on opportunities across the U.S. It also maintains a venture investment arm that backs startups in healthcare, financial technology, big data, clean technology, digital health, food technology, health technology, the Internet of Things, and software as a service, and it pursues impact investments. The firm emphasizes a diversified approach across traditional finance and technology-enabled sectors, aiming to create value for its clients and portfolio companies while supporting sustainable solutions.

Crescendo Capital Partners, established in 2007, is a private equity and venture capital firm headquartered in Centennial, Colorado. The company specializes in growth capital investments, focusing on early and later-stage companies in the lower middle market. Crescendo targets businesses in various sectors, including manufacturing, telecommunications, healthcare, and energy, with a particular focus on the Denver area. The firm typically invests up to $0.5 million in early-stage companies with less than $1 million in revenue and up to $50 million in enterprise value, and up to $100 million in later-stage companies with revenues between $10 million and $100 million. Crescendo seeks to take a significant stake in its portfolio companies, providing them with business expertise, professional networks, and capital resources to drive growth and unlock their full potential.

Flywheel Ventures, established in 1999, is a venture capital firm headquartered in Santa Fe, New Mexico, with additional offices in Albuquerque, New Mexico, and San Francisco, California. The firm specializes in seed and early-stage investments, focusing on information technology services and physical sciences sectors, including software, semiconductors, and clean technology. Flywheel Ventures primarily invests in companies based in the Midwest, Southwestern, and Rockies regions of the United States, with a particular focus on New Mexico, Colorado, and Arizona, while also considering co-investments in California. The firm typically invests between $0.05 million and $1 million initially, with a 3:1 or greater target reserve for follow-on funding. Flywheel Ventures seeks to address key global challenges in information technology and urban systems, often taking a board seat and investing in syndicates to provide follow-on capital.

Costanoa Ventures is a California-based independent venture capital firm founded in 2012 that focuses on early-stage technology companies, including seed and Series A rounds. It targets B2B and enterprise-focused opportunities across cloud-based services, data analytics, applications and infrastructure, fintech, security, modern software as a service, big data, and AI-enabled solutions. The firm backs companies at the forefront of enterprise software, developer infrastructure, cybersecurity, and related technologies, helping startups with go-to-market strategy, product-market fit, and long-term growth. Headquartered in Palo Alto with an additional office in San Francisco, Costanoa Ventures supports entrepreneurs building durable, data-driven businesses.

Sapphire Ventures is a global software-focused venture capital firm with teams across Austin, London, Menlo Park and San Francisco. It partners with visionary management teams and venture funds to back companies that can become category leaders and has backed hundreds of companies worldwide, generating a track record of public listings and acquisitions. The firm operates a multi-pronged platform—Sapphire Ventures, Sapphire Partners and Sapphire Sport—that combines growth and early-stage investing with a portfolio-growth team providing strategic resources and operational support to help portfolio companies scale. Sapphire Sport is an early-stage investment vehicle focused on the intersection of sport, media and entertainment technology, while the broader platform targets software, cloud, cybersecurity, AI and other technology-enabled sectors.

Upslope Ventures, founded in 2014 and based in Denver, Colorado, is an early-stage venture capital firm that invests in startups across the United States. Originally known as Galvanize Ventures, the firm focuses on a diverse range of sectors, including software as a service, hardware and internet of things, mobile, artificial intelligence, consumer products, e-commerce, content, fintech, aerospace, marketplaces, ad-tech, robotics, medical devices, virtual reality, and data science. Upslope Ventures emphasizes the importance of exceptional teams, believing that talent can emerge from any location. Beyond providing capital, the firm leverages its extensive network to empower entrepreneurs with valuable resources and support, enhancing their chances of success even in cases where direct investment is not made.

Founded in 2015, FJ Labs is a New York-based venture capital firm focusing on stage-agnostic investments in marketplaces and consumer-facing startups. Their investment range varies from $50,000 to $5,000,000, typically at seed or series A stages.

Grotech Ventures is a Maryland-based venture capital firm founded in 1984 that focuses on early-stage and growth technology companies across the United States. The firm targets sectors including technology, cybersecurity, fintech, supply chain and logistics, software and vertical software, and TMT. It typically makes initial investments in the low to mid single digits per company and reserves capital for follow-on rounds to support growth through the company’s early and expansion stages. Grotech emphasizes a personal, long-term partnership with entrepreneurs, aligning its support with the founder’s definition of success. Beyond capital, it seeks to contribute through its experience, network, and hands-on involvement to help companies mature and scale.

Insight Partners is a global software investor that partners with growth-stage technology and software companies. The firm focuses on growth-stage software, internet, and data services, with emphasis on fintech, cybersecurity, artificial intelligence and machine learning, DevOps, and healthcare. Based in New York City with offices in London, Tel Aviv, and Palo Alto, Insight Partners has backed more than 750 companies worldwide and has more than 55 portfolio companies that have achieved an IPO. As of 2022, the firm reports over $75 billion in assets under management. It seeks to fund and work closely with visionary executives, providing practical, hands-on software expertise to support growth from initial investment through to IPO.

3Lines is a venture capital firm founded in 2016 and located in Greenwood Village, Colorado. The firm specializes in investing in early-stage companies within the Future of Work, Enterprise and Industry, and AI sectors. 3Lines typically provides funding ranging from $1 million to $5 million for companies in the United States and India that have annual revenues between $1 million and $10 million. The firm's focus is on supporting innovative businesses that are poised for growth in these dynamic and evolving markets.

Caruso Ventures is a Boulder, Colorado-based venture capital firm founded in 2020 that invests in tech-enabled companies led by effective CEOs. It leverages scale-up experience to support the growth of the next generation of tech leaders. The firm is industry agnostic and focuses primarily on Colorado opportunities, where it may lead or participate as a follower. It structures investments through Special Purpose Vehicles to enable participation by other investors in select deals. Typical initial investments range from $500,000 to $1,000,000 at the early revenue ramp stage, with a likelihood of follow-on investments.

Unless is a venture capital firm headquartered in Boulder, Colorado, that funds companies operating in industrial systems and related technologies, pursuing impact-oriented investments that combine financial returns with positive systemic change, partnering with entrepreneurial teams across private and public markets and drawing on a network of experts to provide strategic guidance and resources, and supporting companies at the frontiers of artificial intelligence, robotics, information technology, manufacturing and automation to scale as industry reforms drive climate adaptation and the evolving nature of work, blending venture capital and private equity approaches to identify inflection points in the industrial revolution and accelerate growth while fostering responsible innovation.

High Country Venture, LLC is a venture capital firm based in Boulder, Colorado, established in 2005. Specializing in early-stage investments, the firm focuses primarily on the life sciences sector, including biotechnology, diagnostics, and medical devices, as well as internet technology, information technology, and retail consumer goods. High Country Venture commits at least 50 percent of its capital to "Qualified Businesses" located in economically disadvantaged rural and urban communities that adhere to the small business size standards set by the United States Small Business Administration. The remaining capital is allocated to businesses within Colorado. The firm does not engage in investments related to professional services, banking, real estate development, insurance, oil and gas exploration, or direct gambling sectors.

GAN, established in 2010 and headquartered in Denver, Colorado, is a venture capital firm that serves as the investment arm of the Global Accelerator Network. It specializes in seed and early-stage investments, focusing on sectors such as aerospace, agriculture, analytics, robotics, SaaS, security, space-tech, mobile, transportation, machine learning, internet and information technology, and healthcare. GAN Ventures Fund I, managed by GAN Ventures, targets investing USD 0.1 million in approximately 50 to 60 companies, supporting the activities of accelerators within its network.

Congruent Ventures is a venture capital firm founded in 2017 and based in the San Francisco Bay Area. It specializes in early-stage investments in climate technology and sustainable development across North America, with a focus on mobility and urbanization, energy transition, food and agriculture, and sustainable production and consumption. The firm seeks technology companies that improve energy and resource efficiency and partners with teams capable of scaling hardware, software, or services. Its portfolio spans sectors such as transportation, consumer products, industrials, IT software, and related climate tech areas, reflecting a commitment to backing ventures that deliver measurable environmental impact.

Established in 2019, this fund invests in healthcare companies that have partnerships with institutions on the University of Colorado Anschutz Medical Campus. It focuses on digital health, therapeutics, and devices, managing a $50 million portfolio.

Alta Partners, established in 1996, is a venture capital firm headquartered in Jackson, Wyoming, with additional offices in Denver and Tiburon. The firm specializes in investing in the life sciences and healthcare sectors, focusing on companies that operate in life science, healthcare solutions, and service sectors. Alta Partners is known for its diverse and experienced team, which delivers tangible results for both the companies they invest in and their investors. The firm has evolved its investment strategy over time, currently focusing on stage-agnostic life sciences investments.

Blue Note Ventures is a venture capital firm based in Boulder, Colorado, investing in early-stage technology companies and supporting entrepreneurs in the information technology sector. It provides seed-scale capital, typically in the range of $0.1–$0.5 million per company, to help navigate early growth opportunities.

Kokopelli Capital is a venture capital firm based in Boulder, Colorado, founded in 2016, that makes early-stage investments in companies across the Rocky Mountain region and Austin, focusing on sectors including retail, apparel and accessories, services (non-financial), e-commerce, and technology, media, and telecommunications.

Founded in 2004 and based in Palo Alto, California, Uncork Capital is a venture capital firm focusing on seed-stage investments in SaaS, consumer goods, healthcare, and technology companies across the United States. The firm invests out of two funds: a $200M Seed fund and a $200M Opportunity fund for larger investments in mature portfolio companies.

Founded in 2008 and based in Cottonwood Heights, Utah, Kickstart is a venture capital firm investing in early-stage companies across the Mountain West region. With a focus on technology-related sectors, particularly software, they have supported numerous successful startups such as Lucid, Podium, and Galileo over their 17-year history.

Founded in 1989, OrbiMed is a New York-based healthcare-dedicated investment firm managing approximately $5 billion in assets. It invests across the spectrum of healthcare companies, from private start-ups to large multinational corporations, focusing on biopharmaceuticals, life sciences, digital health, medical devices, and diagnostics sectors globally.

Founded in 2018, this Durango-based firm invests in early-stage startups headquartered across Colorado, focusing on regions outside the Front Range.

Ten Eleven Ventures is a cybersecurity-focused, global venture capital firm that backs cybersecurity companies across stages worldwide, addressing digital security needs. The firm identifies, funds, and helps grow top cybersecurity businesses by leveraging its team, network, and experience. Since its founding, it has raised over $1 billion and completed around 40 cybersecurity investments, including KnowBe4, Darktrace, Twistlock, Verodin, Cylance, and Ping Identity.

CanopyBoulder, established in 2014 and located in Boulder, Colorado, operates as a mentorship-driven seed-stage investment program specifically for startups within the cannabis industry. The firm concentrates on companies that produce ancillary products and services related to marijuana, hemp, and cannabidiol. In addition to its accelerator program, CanopyBoulder manages a venture fund dedicated to supporting businesses in the legal cannabis sector. Through its initiatives, CanopyBoulder aims to foster innovation and growth in the evolving landscape of the cannabis market.

Founded in 2016 and headquartered in Boulder, Colorado, Batshit Crazy Ventures is an early-stage venture capital firm focused on supporting pre-revenue and pre-seed startups.

Founders Fund is a San Francisco-based venture capital firm that backs science and technology companies across multiple stages, from seed to late-stage. It pursues transformative technologies and follows a founder-friendly investment approach that provides substantial support with minimal interference. The firm invests in ventures solving difficult problems across sectors such as aerospace and transportation, artificial intelligence, advanced computing, energy, healthcare, biotechnology, cybersecurity, fintech, consumer internet, software, robotics, and related technology fields. It has backed notable companies early, including SpaceX, Palantir, and Facebook, reflecting a history of partnering with ambitious founders to scale breakthrough technologies.

Sequel Venture Partners is a venture capital firm located in Boulder, Colorado, established in January 1996. The firm specializes in providing funding for seed and early-stage technology companies, primarily focusing on sectors such as healthcare, information technology, clean technology, and internet-based services. Sequel Venture Partners manages approximately $400 million in capital and typically invests in companies situated in the Rocky Mountain region, with a particular emphasis on Colorado. The firm is dedicated to supporting innovative businesses across various industries, including biotechnology, telecommunications, and digital health.

Founded in 2000, Scale Venture Partners is a Silicon Valley-based venture capital firm with $1.3B under management. It focuses on early-stage cloud, SaaS, and infrastructure startups that leverage AI, ML, or automation. The firm provides value acceleration through go-to-market strategies and access to proprietary operational SaaS metrics for benchmarking growth.

eonCapital is a Colorado-based venture capital firm established in 1997, located in Centennial. The firm specializes in investing in seed and early-stage startups that operate in the software-as-a-service (SaaS) and mobile application sectors. eonCapital focuses on supporting innovative entrepreneurs by providing not only financial backing but also essential services such as internet marketing strategy and web development. This approach aims to assist startups in launching and growing their web-based businesses effectively.

Range Ventures is an early-stage venture capital firm based in Denver, Colorado, founded in 2020. The firm specializes in investing in technology-related companies, focusing on pre-seed and seed rounds. Range Ventures aims to support businesses within the Denver, Boulder, and broader Colorado ecosystem, fostering innovation and growth in the region's technology landscape.

UPC Capital Ventures is the venture capital arm of UPC Solar, based in Boulder, Colorado. It invests in companies across consumer, energy, health, water resource management, software as a service, and financial technology sectors, with a focus on energy technology, energy efficiency, energy blockchain, sustainability, and LOHAS. The firm seeks opportunities that align with the UPC Group and its owners' values, supporting innovations that advance sustainability and resource management. It emphasizes identifying startups that enable practical solutions in clean energy, sustainable living, and resource optimization.

Founded in Denver, Colorado in 2016, Rockies Venture Fund is a venture capital firm investing in seed and early-stage companies. It primarily considers investments in startups with a strong team, disruptive product, and significant market potential, aiming for an average return of ten times the fund's investment within five years.

Founded in 2018, Break Trail Ventures is a venture capital firm headquartered in Columbus, Ohio with an additional office in Boulder, Colorado. The firm specializes in early-stage and growth capital investments across sectors such as consumer products, advanced manufacturing, big data, digital health, e-commerce, mobile & SaaS.

Harbert Management is a privately owned investment management firm focused on alternative asset classes, with headquarters in Birmingham, Alabama, and offices across the United States and Europe. Established in 1993, it manages investments across private equity, venture capital, real estate, mezzanine debt, and related strategies. The firm targets value-enhancement real estate through its US Real Estate and European Real Estate platforms and serves a broad client base including foundations and endowments, funds of funds, pension funds, financial institutions, insurance companies, family offices, and high-net-worth individuals. It operates through dedicated investment teams in multiple cities to source and analyze opportunities, and its structure includes subsidiaries such as a venture capital affiliate. The firm emphasizes disciplined, principle-based investing and a global reach to access diverse markets and opportunities.

Denver Angels is a private investment group based in Denver, Colorado, established in 2016. The organization focuses on identifying and supporting the next generation of promising companies within the state. Its investment interests span various sectors, including consumer products, software, and engineering, highlighting a commitment to fostering innovation and growth in Colorado's entrepreneurial landscape.

Mobius Venture Capital is a Colorado-based venture capital firm focused on early-stage technology investments in United States startups. Founded in 1996, it maintains offices in Boulder and Palo Alto and leverages the founders’ and operators’ experience from leading technology companies to support portfolio companies. The firm emphasizes hands-on involvement, providing strategic guidance and operating expertise to help early-stage technology companies grow and navigate scale.

Founded in 2019, Industrious Ventures is a venture capital firm based in Denver, Colorado. The firm invests in early-stage companies focused on transforming industries such as aerospace, autonomous robotics, supply chain, and manufacturing by innovating their respective value chains over extended periods.

7wire Ventures is a Chicago-based venture capital firm founded in 2011 that concentrates on early-stage investments in digital health, healthcare IT, mobility-enabled services, and other technology-enabled solutions in the United States. The firm provides funding and operating guidance to portfolio companies to help transform innovative ideas into scalable, world-class businesses. Its approach leverages mobility, connected devices, cloud computing, and analytics to advance sectors such as healthcare and education and to challenge conventional solutions.