Service Provider Capital is a venture capital firm established in 2014 and based in Colorado. The firm focuses on early-stage investments, notably seed-stage opportunities, and participates as a co-investor in Series A rounds led by institutional venture funds. Its portfolio interests span a broad range of technology sectors, including artificial intelligence, machine learning, blockchain, cybersecurity, e-commerce, education technology, fintech, hardware, information technology, robotics, health, and cannabis.

Foundry Group is a venture capital firm founded in 2007 and based in Boulder, Colorado. It concentrates on information technology, Internet and software companies across North America, backing both early-stage and later-stage ventures in the technology sector. The firm has built a broad portfolio through institutional investments and angel backing, reflecting a consistent focus on partnering with entrepreneurs to scale innovative digital businesses.

Boomtown Accelerator, established in 2014 and based in Boulder, Colorado, is a startup accelerator that invests in early-stage companies, primarily in the advertising technology, internet, mobile, and healthcare technology sectors. It offers a 12-week program, providing selected teams with $20,000 in seed money, access to office space and amenities, and strategic support from partners and staff. The accelerator also connects startups with expert mentors, alumni network, and potential corporate customers and funding sources. Boomtown's approach is tailored to each company's needs, aiming to help startups transform ideas into profitable, scalable businesses.

Founded in 1999, Access Venture Partners is a venture capital firm based in Denver, Colorado. It specializes in seed and early-stage investments in technology companies across the United States, with a focus on software, cybersecurity, big data, clean technology, SaaS, and new media sectors. The firm typically invests between $0.25 million to $2.5 million per company, seeking to take its portfolio companies public within two to four years.

FirstMile Ventures is a venture capital firm specializing in seed and early-stage investments, primarily focusing on B2B software and infrastructure technology companies. Based in Colorado Springs with an additional office in Denver, the firm invests across North America but prefers Colorado-based opportunities. Initial investments typically range from $0.05 million to $1.5 million, with provisions for follow-on financing.

Boulder Ventures is a venture capital firm based in Boulder, Colorado, founded in 1995. It focuses on early-stage information technology and life sciences companies, investing in areas such as communications software and services, network infrastructure, information management, and biotechnology tools including drug discovery. The firm targets opportunities in Colorado and the Mid-Atlantic region and typically participates in initial investments with potential follow-on capital, often aiming to lead deals in its portfolio companies.

Right Side Capital Management is a San Francisco-based venture capital firm founded in 2010 that invests in early-stage technology startups. It specializes in pre-seed and seed rounds for capital-efficient companies, with a focus on the United States and Canada and occasional activity in Western Europe, Israel, Australia, and New Zealand. The firm typically makes 75 to 100 investments per year, with round sizes from 50,000 to 500,000 and pre-money valuations ranging from 1,000,000 to 3,500,000. Portfolio companies are typically located outside the San Francisco Bay Area and New York City, and the firm aims to provide a clear yes or no on opportunities within about two weeks.

Founded in 2013, Matchstick Ventures is a venture capital firm based in Minneapolis, Minnesota. It supports the creation and growth of early-stage technology companies, primarily focusing on seed-stage investments across various sectors such as business products, services, information technology, and TMT.

New Enterprise Associates is a U.S.-based venture capital firm founded in 1977 and headquartered in Menlo Park, California. It invests in technology and healthcare companies across stages and geographies, supporting startups from seed to growth. The firm operates globally with investments in the United States, Asia, and Brazil among others, and has a long track record of portfolio IPOs and acquisitions. It has over $19 billion in cumulative committed capital.

Crescendo Capital Partners, established in 2007, is a private equity and venture capital firm headquartered in Centennial, Colorado. The company specializes in growth capital investments, focusing on early and later-stage companies in the lower middle market. Crescendo targets businesses in various sectors, including manufacturing, telecommunications, healthcare, and energy, with a particular focus on the Denver area. The firm typically invests up to $0.5 million in early-stage companies with less than $1 million in revenue and up to $50 million in enterprise value, and up to $100 million in later-stage companies with revenues between $10 million and $100 million. Crescendo seeks to take a significant stake in its portfolio companies, providing them with business expertise, professional networks, and capital resources to drive growth and unlock their full potential.

Flywheel Ventures is a Santa Fe-based venture capital firm that funds seed to early-stage technology companies, with a regional emphasis on the Southwest and Rocky Mountain states. The firm backs information technology, software and related sectors, including B2B products, software-as-a-service, semiconductors, networking, data services, and other technology domains, and seeks to invest in companies with solutions addressing global IT and urban systems challenges. It maintains offices in Albuquerque and San Francisco and typically acts as a lead investor, aiming to take a board seat and to syndicate for follow-on financing. While focused on the United States, its regional roots are in New Mexico, Colorado and Arizona, with investment activity also in California. Flywheel pursues seed-to-early-stage opportunities and up to growth capital for portfolio companies, collaborating with other firms to support scale.

Costanoa Ventures is a Palo Alto-based venture capital firm founded in 2012 by Greg Sands. It focuses on early-stage technology companies, investing primarily in seed and Series A rounds across B2B sectors, including enterprise software, data and analytics, developer infrastructure, fintech, cybersecurity, and national security. The firm positions itself as a long-term partner to entrepreneurs, helping portfolio companies with go-to-market strategy, product-market fit, and growth. It supports startups aiming to build durable, data-driven businesses and strives to back companies that transform how enterprises operate.

Founded in 2005, Iron Gate Capital is a venture capital firm based in Louisville, Colorado. It primarily invests in enterprise technology companies at the early growth stage, with initial investments ranging from $3 to $5 million.

Alumni Ventures Group is a venture capital firm based in Manchester, New Hampshire, established in 2013. It targets individual accredited investors who previously had limited access to venture capital by enabling alumni from top entrepreneurial schools to invest together in ventures led by fellow alumni. The firm backs companies with an alumni connection and an institutional lead investor with sector expertise. It offers focused funds that provide accredited investors access to a diversified venture portfolio by type, sector, stage, and geography. The organization engages in seed, early-stage, and late-stage pre-IPO investments across technology, consumer, financial services, health care, life sciences, and other sectors.

Sapphire Ventures is a global software-focused venture capital firm with teams across Austin, London, Menlo Park and San Francisco. It partners with visionary management teams and venture funds to back companies that can become category leaders and has backed hundreds of companies worldwide, generating a track record of public listings and acquisitions. The firm operates a multi-pronged platform—Sapphire Ventures, Sapphire Partners and Sapphire Sport—that combines growth and early-stage investing with a portfolio-growth team providing strategic resources and operational support to help portfolio companies scale. Sapphire Sport is an early-stage investment vehicle focused on the intersection of sport, media and entertainment technology, while the broader platform targets software, cloud, cybersecurity, AI and other technology-enabled sectors.

Range Ventures is an early-stage venture capital firm based in Denver, Colorado. The firm invests in tech-related companies at pre-seed and seed stages, focusing on opportunities in Denver, Boulder, and the broader Colorado ecosystem.

Grotech Ventures is a Maryland-based venture capital firm founded in 1984 that focuses on early-stage and growth technology companies across the United States. The firm targets sectors including technology, cybersecurity, fintech, supply chain and logistics, software and vertical software, and TMT. It typically makes initial investments in the low to mid single digits per company and reserves capital for follow-on rounds to support growth through the company’s early and expansion stages. Grotech emphasizes a personal, long-term partnership with entrepreneurs, aligning its support with the founder’s definition of success. Beyond capital, it seeks to contribute through its experience, network, and hands-on involvement to help companies mature and scale.

Congruent Ventures is a venture capital firm based in Oakland and San Francisco that specializes in early-stage investments in climate technology and sustainable solutions across North America. The firm backs technology companies in mobility and urbanization, energy transition, food and agriculture, and sustainable production and consumption, with opportunities spanning hardware, software, and services that can scale while reducing energy and resource use. Founded in 2017, Congruent Ventures emphasizes positive environmental impact alongside growth and operates as an exempt registered adviser.

Caruso Ventures is a Boulder, Colorado-based venture capital firm founded in 2020 that invests in tech-enabled companies led by effective CEOs. It leverages scale-up experience to support the growth of the next generation of tech leaders. The firm is industry agnostic and focuses primarily on Colorado opportunities, where it may lead or participate as a follower. It structures investments through Special Purpose Vehicles to enable participation by other investors in select deals. Typical initial investments range from $500,000 to $1,000,000 at the early revenue ramp stage, with a likelihood of follow-on investments.

Upslope Ventures, founded in 2014 and based in Denver, Colorado, is an early-stage venture capital firm that invests in startups across the United States. Originally known as Galvanize Ventures, the firm focuses on a diverse range of sectors, including software as a service, hardware and internet of things, mobile, artificial intelligence, consumer products, e-commerce, content, fintech, aerospace, marketplaces, ad-tech, robotics, medical devices, virtual reality, and data science. Upslope Ventures emphasizes the importance of exceptional teams, believing that talent can emerge from any location. Beyond providing capital, the firm leverages its extensive network to empower entrepreneurs with valuable resources and support, enhancing their chances of success even in cases where direct investment is not made.

Greenline Ventures is a Denver, Colorado-based investment firm that provides capital solutions to the financial services sector and related technology-enabled industries across the United States. It pursues buyout investments in financial services and engages in capital markets activities, with an emphasis on long-term value and impact.

SpringTime Ventures is a venture capital firm founded in 2016 and based in Denver, Colorado. It seeds high-growth software-focused startups across technology, healthcare, fintech, insurtech, and logistics, seeking founders with domain expertise to back transformative technologies. The firm concentrates on software-enabled businesses in the United States and emphasizes a people-focused approach, speed in decision-making, and independently formed conviction. Typical initial investments are around $600,000, reflecting its early-stage mandate.

Next Frontier Capital is a venture capital investment firm based in Bozeman, Montana, founded in 2015. It partners with mission-driven, talented entrepreneurs to build technology companies and focuses on early-stage investments in biotech, clean-tech, healthcare, and technology in the United States. The firm pursues opportunities in the Mountain region and maintains additional offices in Boulder, Missoula, and Salt Lake City, with a portfolio spanning software, pharmaceutical and biotechnology sectors.

MergeLane, founded in 2015, is a venture capital firm headquartered in Boulder, Colorado. It specializes in investing in high-potential startups and venture capital funds led by at least one female leader.

Insight Partners is a global software investor that partners with growth-stage technology and software companies. Headquartered in New York City with offices in London, Tel Aviv, and Palo Alto, it concentrates on growth-stage software, internet, and data services, with notable focus areas including fintech, cybersecurity, AI/ML, DevOps, and healthcare. Founded in 1995, Insight Partners manages over $75 billion in regulatory assets under management and has invested in more than 750 companies worldwide, with over 55 portfolio companies achieving an IPO. The firm combines capital with hands-on, right-sized software expertise to support portfolio companies on their growth journey from first investment to IPO.

Stout Street Capital is a Denver, Colorado-based venture capital firm that backs early-stage technology companies. It concentrates on software and B2B SaaS, while also investing in fintech, advanced materials, robotics, and artificial intelligence. The firm targets opportunities in under-served markets in the central United States, with a particular emphasis on the Rocky Mountain region. Its approach combines data-driven analysis, market assessment, and thorough due diligence to select ventures that can improve efficiency and generate measurable value as they scale.

Kickstart Fund is a Utah-based seed-stage venture capital firm that backs early-stage technology companies in the Mountain West. Based in Cottonwood Heights/Salt Lake City, it provides smart capital, a connected founder community, and expert guidance to help portfolio companies grow. Founded in 2008, Kickstart has supported numerous startups and targets investments in software, information technology, and related technology sectors across Utah and neighboring Mountain West states, with a focus on helping founders scale through capital, mentorship, and strategic resources.

High Country Venture, LLC is a venture capital firm based in Boulder, Colorado, established in 2005. Specializing in early-stage investments, the firm focuses primarily on the life sciences sector, including biotechnology, diagnostics, and medical devices, as well as internet technology, information technology, and retail consumer goods. High Country Venture commits at least 50 percent of its capital to "Qualified Businesses" located in economically disadvantaged rural and urban communities that adhere to the small business size standards set by the United States Small Business Administration. The remaining capital is allocated to businesses within Colorado. The firm does not engage in investments related to professional services, banking, real estate development, insurance, oil and gas exploration, or direct gambling sectors.

Alta Partners, established in 1996, is a venture capital firm headquartered in Jackson, Wyoming, with additional offices in Denver and Tiburon. The firm specializes in investing in the life sciences and healthcare sectors, focusing on companies that operate in life science, healthcare solutions, and service sectors. Alta Partners is known for its diverse and experienced team, which delivers tangible results for both the companies they invest in and their investors. The firm has evolved its investment strategy over time, currently focusing on stage-agnostic life sciences investments.

Unless is a venture capital firm headquartered in Boulder, Colorado, that funds companies operating in industrial systems and related technologies, pursuing impact-oriented investments that combine financial returns with positive systemic change, partnering with entrepreneurial teams across private and public markets and drawing on a network of experts to provide strategic guidance and resources, and supporting companies at the frontiers of artificial intelligence, robotics, information technology, manufacturing and automation to scale as industry reforms drive climate adaptation and the evolving nature of work, blending venture capital and private equity approaches to identify inflection points in the industrial revolution and accelerate growth while fostering responsible innovation.

Established in 2019, this fund invests in healthcare companies that have partnerships with institutions on the University of Colorado Anschutz Medical Campus. It focuses on digital health, therapeutics, and devices, managing a $50 million portfolio.

Tao Capital Partners is a venture capital firm based in San Francisco, California, founded in 2002. The firm focuses on investing in sectors such as technology, transportation, healthcare, education, and sustainable food, with an emphasis on businesses that create a positive social and environmental impact. Tao Capital Partners actively supports companies throughout various stages of their development, aiming to foster growth and innovation in its portfolio. The firm also explores opportunities in alternative energy, agriculture, consumer products, real estate, and hospitality, demonstrating a broad approach to investment in sustainable and impactful industries.

Founded in 2016 and headquartered in Boulder, Colorado, Batshit Crazy Ventures is an early-stage venture capital firm focused on supporting pre-revenue and pre-seed startups.

Founded in 2015, FJ Labs is a New York-based venture capital firm focusing on stage-agnostic investments in marketplaces and consumer-facing startups. Their investment range varies from $50,000 to $5,000,000, typically at seed or series A stages.

3Lines is a venture capital firm founded in 2016 and located in Greenwood Village, Colorado. The firm specializes in investing in early-stage companies within the Future of Work, Enterprise and Industry, and AI sectors. 3Lines typically provides funding ranging from $1 million to $5 million for companies in the United States and India that have annual revenues between $1 million and $10 million. The firm's focus is on supporting innovative businesses that are poised for growth in these dynamic and evolving markets.

Kokopelli Capital is a venture capital firm based in Boulder, Colorado, founded in 2016, that makes early-stage investments in companies across the Rocky Mountain region and Austin, focusing on sectors including retail, apparel and accessories, services (non-financial), e-commerce, and technology, media, and telecommunications.

Established in 2020 and headquartered in Denver, Colorado, Ensemble Innovation Ventures is a venture capital firm focused on investing in early-stage healthcare technology companies.

CanopyBoulder is an accelerator based in Boulder, Colorado, founded in 2014. It runs a mentorship-driven seed-stage program for startups in the cannabis industry, with emphasis on ancillary products and services. The program supports early-stage ventures by providing guidance, mentorship, and access to a network to help scale businesses within the legal cannabis sector.

Founded in 1989, OrbiMed is a New York-based healthcare-dedicated investment firm managing approximately $5 billion in assets. It invests across the spectrum of healthcare companies, from private start-ups to large multinational corporations, focusing on biopharmaceuticals, life sciences, digital health, medical devices, and diagnostics sectors globally.

Ten Eleven Ventures is a cybersecurity-focused, global venture capital firm that backs cybersecurity companies across stages worldwide, addressing digital security needs. The firm identifies, funds, and helps grow top cybersecurity businesses by leveraging its team, network, and experience. Since its founding, it has raised over $1 billion and completed around 40 cybersecurity investments, including KnowBe4, Darktrace, Twistlock, Verodin, Cylance, and Ping Identity.

Sequel Venture Partners is a venture capital firm located in Boulder, Colorado, established in January 1996. The firm specializes in providing funding for seed and early-stage technology companies, primarily focusing on sectors such as healthcare, information technology, clean technology, and internet-based services. Sequel Venture Partners manages approximately $400 million in capital and typically invests in companies situated in the Rocky Mountain region, with a particular emphasis on Colorado. The firm is dedicated to supporting innovative businesses across various industries, including biotechnology, telecommunications, and digital health.

eonCapital is a Colorado-based venture capital firm established in 1997, located in Centennial. The firm specializes in investing in seed and early-stage startups that operate in the software-as-a-service (SaaS) and mobile application sectors. eonCapital focuses on supporting innovative entrepreneurs by providing not only financial backing but also essential services such as internet marketing strategy and web development. This approach aims to assist startups in launching and growing their web-based businesses effectively.

Scale Venture Partners is a Foster City, California-based venture capital firm that backs early-stage technology companies, focusing on intelligent business software, cloud infrastructure, SaaS, AI and machine learning, and related information technology sectors. The firm supports growth through a Scaling Platform that provides go-to-market guidance, playbooks, and access to a proprietary dataset of operational SaaS metrics used to benchmark growth, efficiency, churn and burn, helping founders move from first customers to market leadership. Scale Venture Partners targets seed and early-stage investments in AI-enabled applications, fintech, security, productivity, vertical software and other technology sectors, and has helped portfolio companies such as Box, Bill.com, HubSpot, DocuSign, JFrog and WalkMe accelerate scale.

Founded in 1995, Crawley Ventures is a Denver-based venture capital firm that invests in seed, early, and expansion stage companies across various industries such as high tech optics, financial services, software, manufacturing, and wireless technologies. The firm takes an 'old-school' approach, acting as investors and partners to portfolio companies, seeking opportunities with strong management teams and growth potential.

Founders Fund is a San Francisco-based venture capital firm that backs science and technology companies across multiple stages, from seed to late-stage. It pursues transformative technologies and follows a founder-friendly investment approach that provides substantial support with minimal interference. The firm invests in ventures solving difficult problems across sectors such as aerospace and transportation, artificial intelligence, advanced computing, energy, healthcare, biotechnology, cybersecurity, fintech, consumer internet, software, robotics, and related technology fields. It has backed notable companies early, including SpaceX, Palantir, and Facebook, reflecting a history of partnering with ambitious founders to scale breakthrough technologies.

Founded in 2018, Break Trail Ventures is a venture capital firm headquartered in Columbus, Ohio with an additional office in Boulder, Colorado. The firm specializes in early-stage and growth capital investments across sectors such as consumer products, advanced manufacturing, big data, digital health, e-commerce, mobile & SaaS.

UPC Capital Ventures is the venture capital arm of UPC Solar, based in Boulder, Colorado. It invests in companies across consumer, energy, health, water resource management, software as a service, and financial technology sectors, with a focus on energy technology, energy efficiency, energy blockchain, sustainability, and LOHAS. The firm seeks opportunities that align with the UPC Group and its owners' values, supporting innovations that advance sustainability and resource management. It emphasizes identifying startups that enable practical solutions in clean energy, sustainable living, and resource optimization.

SOSV is a global venture capital firm that supports early-stage startups through active, founder-first development programs. Its flagship initiatives HAX and IndieBio provide facilities, engineering resources, services, and laboratory equipment to accelerate product development and prepare companies for subsequent funding rounds. SOSV focuses on deep technology across health, environmental, and cross-border software sectors, aiming to solve human and planetary health challenges. In addition to providing capital, the firm emphasizes intensive programmatic support to help portfolio companies move quickly from seed toward growth, including customer acquisition and scale. The firm operates globally with a bias toward startups targeting rapid international expansion, especially in Asia, and tends to back a small cohort of high-potential companies to accelerate their progress and attract leading investors.

Mobius Venture Capital is a Colorado-based venture capital firm that invests in early-stage technology companies in the United States. It has offices in Boulder and Palo Alto. The firm was established in the mid-1990s and has backed more than sixty technology companies, offering portfolio companies hands-on operational support.

Denver Angels is a private investment group based in Denver, Colorado, established in 2016. The organization focuses on identifying and supporting the next generation of promising companies within the state. Its investment interests span various sectors, including consumer products, software, and engineering, highlighting a commitment to fostering innovation and growth in Colorado's entrepreneurial landscape.