Prolog Ventures

Prolog Ventures is a venture capital firm based in St. Louis, Missouri, established in 2001. The firm focuses on investments in startups and early-stage companies, primarily within the life sciences and healthcare sectors. It also targets fast-moving consumer goods, particularly in areas related to nutrition, wellness, and green technology. Prolog Ventures emphasizes investments in consumer health and wellness products that aim to enhance the health and well-being of individuals and their companion animals. This includes sectors such as personal care, functional foods and beverages, medical foods, dietary supplements, and home care. The firm predominantly invests in North America, seeking innovative business models and proprietary technologies that align with its mission.

Brian Clevinger Ph.D

Founder and Managing Director

Gregory R. Johnson

Co-Founder and MD

Greg Johnson

Founder and Managing Director

Ilya Nykin

Founder and Managing Director

Robert M. Rosenberg

Managing Director

Teddy Shalon

Technology Partner

72 past transactions

Benson Hill

Series D in 2020
Benson Hill is an agricultural technology company focused on crop improvement, particularly in soy protein innovation. By leveraging its proprietary CropOS™ platform, the company integrates machine learning, genomic data, and traditional breeding techniques to streamline the development of healthier and more sustainable food products. Benson Hill emphasizes unlocking the natural genetic diversity of plants to empower innovators in creating flavorful and nutritious ingredients. The company operates a Crop Accelerator for rapid prototyping and is developing a diverse seed portfolio that includes protein ingredients, aquaculture, specialty animal feed, and vegetable oils. Its revenue is generated from both proprietary and non-proprietary product categories, reflecting its commitment to advancing agricultural innovation.

CleanSlate UV

Series A in 2020
CleanSlate UV develops sanitization devices aimed at disinfecting smartphones and other portable electronics. The company's technology allows staff, patients, and visitors to effectively sanitize their personal items while also promoting hand hygiene, thereby reducing the risk of hospital-acquired infections. By harnessing the power of UV light, CleanSlate UV's products are designed to eliminate harmful pathogens without damaging sensitive touch screens. The devices not only ensure effective disinfection but also collect data for sanitization compliance, addressing the increasing challenge of device hygiene in various environments.

Covercress

Venture Round in 2020
CoverCress is a biotechnology company that focuses on research and development of renewable fuel and livestock feed. It specializes in producing an oilseed crop for food, bioenergy, and cattle feed. It specializes in the fields of agriculture, biotechnology, plants, genetics, cover crop, and precision agriculture. CoverCress was founded in 2013 by Jerry Steiner and Dr. Tim Ulmasov and is headquartered in St. Louis Missouri.

Kinnos

Venture Round in 2020
Kinnos Inc. manufactures a powdered additive for infectious disease decontamination. The company provides Highlight, a patent-pending additive for disinfectants. It also provides real-time color-change feedback to enforce thoroughness of cleaning. In addition, it also provides Highlight Wipes, a wipe dispensing machine and Highlight Powder, a disinfectant additive. The company was incorporated in 2014 and is based in Brooklyn, New York.

Kinnos

Series A in 2020
Kinnos Inc. manufactures a powdered additive for infectious disease decontamination. The company provides Highlight, a patent-pending additive for disinfectants. It also provides real-time color-change feedback to enforce thoroughness of cleaning. In addition, it also provides Highlight Wipes, a wipe dispensing machine and Highlight Powder, a disinfectant additive. The company was incorporated in 2014 and is based in Brooklyn, New York.

bioClarity

Venture Round in 2019
BioClarity is an online marketplace focused on addressing the skincare needs of young adults, particularly in the realm of acne treatment. The company offers a variety of botanical and plant-based skincare products that are clinically tested to effectively reduce redness and pore size. By combining natural ingredients with scientific research, BioClarity aims to provide customers with chemical-free beauty solutions that promote healthy, glowing skin at an affordable price. This approach reflects a commitment to meeting the demands of a market increasingly seeking effective and environmentally friendly skincare options.

CareDox

Series C in 2019
CareDox Inc. operates a care coordination platform designed to assist parents and schools in managing and sharing medical information effectively. Founded in 2010 and based in New York, the company focuses on streamlining the collection and accessibility of health data to enhance child safety. Its platform enables parents to organize their family's health information, eliminating the need for paper forms during school, camp, and daycare enrollment. Parents can selectively share health information while maintaining a secure record of their children's medical history. For schools, CareDox facilitates the medical enrollment process, ensuring compliance with safety requirements and providing school staff, including nurses and teachers, with essential health information about students. This access allows for real-time insights into allergies, medications, and special dietary needs, ultimately improving health outcomes and supporting the continuity of care for children in the K-12 education system.

Covercress

Venture Round in 2018
CoverCress is a biotechnology company that focuses on research and development of renewable fuel and livestock feed. It specializes in producing an oilseed crop for food, bioenergy, and cattle feed. It specializes in the fields of agriculture, biotechnology, plants, genetics, cover crop, and precision agriculture. CoverCress was founded in 2013 by Jerry Steiner and Dr. Tim Ulmasov and is headquartered in St. Louis Missouri.

Toma Biosciences

Series C in 2018
TOMA Biosciences, Inc. develops reagent kits that enable laboratories and researchers to uncover genomic changes in tumors. The company offers TOMA OS-Seq, an oncology-focused gene analysis solution. It serves laboratories, hospital systems, and research institutions worldwide. The company was incorporated in 2011 and is based in Foster City, California.

Spindrift

Series B in 2018
Spindrift is a food and beverage company that produces a line of unsweetened sparkling beverages made with real squeezed fruit. They offer sparkling water plus real fruit with different flavors. They also provide drinks such as half and a half which is tea brewed with lemon, raspberry lime, strawberry, and many more. It was founded in 2010 and is based in Newton, Massachusetts.

Benson Hill

Series B in 2017
Benson Hill is an agricultural technology company focused on crop improvement, particularly in soy protein innovation. By leveraging its proprietary CropOS™ platform, the company integrates machine learning, genomic data, and traditional breeding techniques to streamline the development of healthier and more sustainable food products. Benson Hill emphasizes unlocking the natural genetic diversity of plants to empower innovators in creating flavorful and nutritious ingredients. The company operates a Crop Accelerator for rapid prototyping and is developing a diverse seed portfolio that includes protein ingredients, aquaculture, specialty animal feed, and vegetable oils. Its revenue is generated from both proprietary and non-proprietary product categories, reflecting its commitment to advancing agricultural innovation.

Spindrift

Series B in 2017
Spindrift is a food and beverage company that produces a line of unsweetened sparkling beverages made with real squeezed fruit. They offer sparkling water plus real fruit with different flavors. They also provide drinks such as half and a half which is tea brewed with lemon, raspberry lime, strawberry, and many more. It was founded in 2010 and is based in Newton, Massachusetts.

Covercress

Venture Round in 2017
CoverCress is a biotechnology company that focuses on research and development of renewable fuel and livestock feed. It specializes in producing an oilseed crop for food, bioenergy, and cattle feed. It specializes in the fields of agriculture, biotechnology, plants, genetics, cover crop, and precision agriculture. CoverCress was founded in 2013 by Jerry Steiner and Dr. Tim Ulmasov and is headquartered in St. Louis Missouri.

CareDox

Series B in 2016
CareDox Inc. operates a care coordination platform designed to assist parents and schools in managing and sharing medical information effectively. Founded in 2010 and based in New York, the company focuses on streamlining the collection and accessibility of health data to enhance child safety. Its platform enables parents to organize their family's health information, eliminating the need for paper forms during school, camp, and daycare enrollment. Parents can selectively share health information while maintaining a secure record of their children's medical history. For schools, CareDox facilitates the medical enrollment process, ensuring compliance with safety requirements and providing school staff, including nurses and teachers, with essential health information about students. This access allows for real-time insights into allergies, medications, and special dietary needs, ultimately improving health outcomes and supporting the continuity of care for children in the K-12 education system.

CareDox

Debt Financing in 2016
CareDox Inc. operates a care coordination platform designed to assist parents and schools in managing and sharing medical information effectively. Founded in 2010 and based in New York, the company focuses on streamlining the collection and accessibility of health data to enhance child safety. Its platform enables parents to organize their family's health information, eliminating the need for paper forms during school, camp, and daycare enrollment. Parents can selectively share health information while maintaining a secure record of their children's medical history. For schools, CareDox facilitates the medical enrollment process, ensuring compliance with safety requirements and providing school staff, including nurses and teachers, with essential health information about students. This access allows for real-time insights into allergies, medications, and special dietary needs, ultimately improving health outcomes and supporting the continuity of care for children in the K-12 education system.

Intellicyt

Venture Round in 2015
IntelliCyt Corporation specializes in developing and marketing high-throughput cell and bead-based screening solutions for the life sciences sector. Established in 2006 and based in Albuquerque, New Mexico, the company offers innovative products, including the iQue Screener platform, which integrates instruments, software, and reagents for high-content multiplexed analysis of cell and bead samples. IntelliCyt's ForeCyt software facilitates data visualization and analysis, while its MultiCyt screening kits provide essential reagents for use with iQue Screeners. These solutions significantly enhance the speed and cost-effectiveness of detecting and measuring cells, catering to the needs of pharmaceutical and biotechnology companies, as well as medical research institutions. By combining flow cytometry with patented sample processing technology, IntelliCyt has created a platform that accelerates suspension cell assays, enabling researchers to achieve higher productivity in drug discovery, antibody development, and toxicology studies. The company also provides installation, training, and technical support services to its clients. IntelliCyt operates as a subsidiary of Sartorius AG.

Veran Medical Technologies

Venture Round in 2015
Veran Medical Technologies is an image-guided medical device company that helps physicians diagnose disease and deliver therapies. It develops a suite of products to enable physicians to diagnose disease and deliver therapies. It offers standards for minimally invasive delivery of interventional oncology therapies. The company provides plug-n-play delivery systems and navigated instruments. Its IG4 Platform allows clinicians to visualize various types of information integrated with a CT dataset, such as respiration, contrast-enhanced structures, PET, and ultrasound. The company also provides SPiN Drive System that acts as a GPS-like system to enable pulmonologists and surgeons to access peripheral solitary pulmonary nodules to diagnose malignancy. The company was incorporated in 2007 and is headquartered in St. Louis, Missouri.

Benson Hill

Series A in 2015
Benson Hill is an agricultural technology company focused on crop improvement, particularly in soy protein innovation. By leveraging its proprietary CropOS™ platform, the company integrates machine learning, genomic data, and traditional breeding techniques to streamline the development of healthier and more sustainable food products. Benson Hill emphasizes unlocking the natural genetic diversity of plants to empower innovators in creating flavorful and nutritious ingredients. The company operates a Crop Accelerator for rapid prototyping and is developing a diverse seed portfolio that includes protein ingredients, aquaculture, specialty animal feed, and vegetable oils. Its revenue is generated from both proprietary and non-proprietary product categories, reflecting its commitment to advancing agricultural innovation.

NeuroLutions

Venture Round in 2015
NeuroLutions Inc. is a company based in St. Louis, Missouri, that specializes in developing brain-computer interface (BCI) devices aimed at restoring functions for patients disabled by neurological injuries. Founded in 2007, the company focuses on creating non-invasive neurorehabilitation devices that assist stroke survivors in regaining lost arm function. Utilizing non-invasive electroencephalography (EEG) electrodes, NeuroLutions' technology captures brain activity without the need for implanted electrodes. This EEG data is wirelessly transmitted to a tablet, where it is analyzed to interpret the patient's intended muscle movements. The devices facilitate muscle re-education and help maintain or enhance the range of motion, offering a promising avenue for rehabilitation in individuals affected by neurological conditions.

Covercress

Series A in 2015
CoverCress is a biotechnology company that focuses on research and development of renewable fuel and livestock feed. It specializes in producing an oilseed crop for food, bioenergy, and cattle feed. It specializes in the fields of agriculture, biotechnology, plants, genetics, cover crop, and precision agriculture. CoverCress was founded in 2013 by Jerry Steiner and Dr. Tim Ulmasov and is headquartered in St. Louis Missouri.

Veran Medical Technologies

Venture Round in 2014
Veran Medical Technologies is an image-guided medical device company that helps physicians diagnose disease and deliver therapies. It develops a suite of products to enable physicians to diagnose disease and deliver therapies. It offers standards for minimally invasive delivery of interventional oncology therapies. The company provides plug-n-play delivery systems and navigated instruments. Its IG4 Platform allows clinicians to visualize various types of information integrated with a CT dataset, such as respiration, contrast-enhanced structures, PET, and ultrasound. The company also provides SPiN Drive System that acts as a GPS-like system to enable pulmonologists and surgeons to access peripheral solitary pulmonary nodules to diagnose malignancy. The company was incorporated in 2007 and is headquartered in St. Louis, Missouri.

AirXpanders

Series E in 2014
AirXpanders develop technology enabling tissue expansion after reconstructive surgery with an emphasis on breast reconstruction. It addresses current unmet needs for patients who require tissue expansion after reconstructive surgery with the first emphasis on breast reconstruction. Present methods of tissue expansion utilize saline-filled implants that are typically injected on a weekly basis after surgery in order to reach the volume of skin and tissue required for the placement of a permanent breast implant.

Veran Medical Technologies

Debt Financing in 2014
Veran Medical Technologies is an image-guided medical device company that helps physicians diagnose disease and deliver therapies. It develops a suite of products to enable physicians to diagnose disease and deliver therapies. It offers standards for minimally invasive delivery of interventional oncology therapies. The company provides plug-n-play delivery systems and navigated instruments. Its IG4 Platform allows clinicians to visualize various types of information integrated with a CT dataset, such as respiration, contrast-enhanced structures, PET, and ultrasound. The company also provides SPiN Drive System that acts as a GPS-like system to enable pulmonologists and surgeons to access peripheral solitary pulmonary nodules to diagnose malignancy. The company was incorporated in 2007 and is headquartered in St. Louis, Missouri.

Spindrift

Venture Round in 2014
Spindrift is a food and beverage company that produces a line of unsweetened sparkling beverages made with real squeezed fruit. They offer sparkling water plus real fruit with different flavors. They also provide drinks such as half and a half which is tea brewed with lemon, raspberry lime, strawberry, and many more. It was founded in 2010 and is based in Newton, Massachusetts.

Singulex

Series G in 2013
Singulex, Inc., a biotechnology company, develops and commercializes direct molecular detection technology solutions. Its solutions enable life science researchers and clinicians to understand and manage disease. The company develops biomarker diagnostic systems that can detect and quantify normal and abnormal protein biomarkers. It is conducting pilot studies to validate Erenna BioAssay System, a digital molecule detection platform, which detects and quantifies molecule biomarkers in clinical samples. The company also offers various custom assay services, such as pilot study services, assay prototyping, assay characterization, and assay validation. The company was formerly known as BioProfile Corporation and changed its name to Singulex, Inc in September 2003. Singulex is based in Hayward, California

EndoStim

Series D in 2013
EndoStim, Inc., a medical device company, develops and commercializes neurostimulation solutions for the treatment of gastro-esophageal reflux disease (GERD). Its solutions cover treatment for GERD through electrical stimulation. The company distributes its products throughout Europe, Asia, and Latin America. EndoStim was founded in 2009 and is based in Dallas, Texas.

Veniti

Series B in 2013
VENITI is the first medical device company developing a suite of innovative technology and solutions that will provide comprehensive treatment across the venous disease continuum. Venous disease refers to all conditions related to or caused by veins that become diseased or abnormal. This encompasses a broad set of maladies. The venous disease cycle begins when vein walls become weak or damaged, or the valves are stretched or injured, and can no longer prevent reflux (backward flow of blood). Once the veins lose their ability to convey blood without reflux, the progressive venous disease cycle has begun. This is commonly referred to as chronic venous insufficiency, or CVI. The blood will begin to back up into the peripheral veins, causing venous hypertension, potential thrombosis (clotting), and leading to even more damage of the vein walls and valves. This in turn leads to more reflux. The VENITI team of experts in science, technology and business are currently developing the VENITI VICI VENOUS STENT® System. Through this, and other, innovative technology, VENITI will achieve results that sets it apart in addressing the challenges specific to the venous system and venous disease.

AirXpanders

Series E in 2013
AirXpanders develop technology enabling tissue expansion after reconstructive surgery with an emphasis on breast reconstruction. It addresses current unmet needs for patients who require tissue expansion after reconstructive surgery with the first emphasis on breast reconstruction. Present methods of tissue expansion utilize saline-filled implants that are typically injected on a weekly basis after surgery in order to reach the volume of skin and tissue required for the placement of a permanent breast implant.

Intellicyt

Venture Round in 2013
IntelliCyt Corporation specializes in developing and marketing high-throughput cell and bead-based screening solutions for the life sciences sector. Established in 2006 and based in Albuquerque, New Mexico, the company offers innovative products, including the iQue Screener platform, which integrates instruments, software, and reagents for high-content multiplexed analysis of cell and bead samples. IntelliCyt's ForeCyt software facilitates data visualization and analysis, while its MultiCyt screening kits provide essential reagents for use with iQue Screeners. These solutions significantly enhance the speed and cost-effectiveness of detecting and measuring cells, catering to the needs of pharmaceutical and biotechnology companies, as well as medical research institutions. By combining flow cytometry with patented sample processing technology, IntelliCyt has created a platform that accelerates suspension cell assays, enabling researchers to achieve higher productivity in drug discovery, antibody development, and toxicology studies. The company also provides installation, training, and technical support services to its clients. IntelliCyt operates as a subsidiary of Sartorius AG.

Akermin

Venture Round in 2013
Akermin, Inc., a biocatalyst development company, develops a solution to remove carbon dioxide (CO2) from industrial gas streams using biocatalysis and nanotechnology. The company offers proprietary delivery systems to integrate enzymes into conventional processes for CO2 removal using chemical absorption. Its technology serves a range of industries and markets in the United States. The company was founded in 2003 and is based in St. Louis, Missouri.

EndoStim

Series C in 2013
EndoStim, Inc., a medical device company, develops and commercializes neurostimulation solutions for the treatment of gastro-esophageal reflux disease (GERD). Its solutions cover treatment for GERD through electrical stimulation. The company distributes its products throughout Europe, Asia, and Latin America. EndoStim was founded in 2009 and is based in Dallas, Texas.

AirXpanders

Series D in 2012
AirXpanders develop technology enabling tissue expansion after reconstructive surgery with an emphasis on breast reconstruction. It addresses current unmet needs for patients who require tissue expansion after reconstructive surgery with the first emphasis on breast reconstruction. Present methods of tissue expansion utilize saline-filled implants that are typically injected on a weekly basis after surgery in order to reach the volume of skin and tissue required for the placement of a permanent breast implant.

Zeel

Seed Round in 2012
Zeel Networks, Inc. offers Zeel, a solution to book same-day in-home massages with licensed and vetted therapists in New York City, Long Island/The Hamptons, Los Angeles, Miami/Palm Beach, Baltimore, and San Francisco Bay Area, as well as in Nashville, Tennessee. It allows users to book chair massage sessions via its iPhone or Android applications, web site, and mobile site. The company also provides Zeel Spa, a staffing solution for spas, salons, and hotels to book a licensed, vetted Zeel massage therapist to fill vacant appointments due to last-minute staff absences. It also delivers massage on demand services in Madison and Milwaukee, Wisconsin; and Louisville, Kentucky. Zeel Networks, Inc. was founded in 2010 and is based in New York, New York.

Singulex

Series F in 2012
Singulex, Inc., a biotechnology company, develops and commercializes direct molecular detection technology solutions. Its solutions enable life science researchers and clinicians to understand and manage disease. The company develops biomarker diagnostic systems that can detect and quantify normal and abnormal protein biomarkers. It is conducting pilot studies to validate Erenna BioAssay System, a digital molecule detection platform, which detects and quantifies molecule biomarkers in clinical samples. The company also offers various custom assay services, such as pilot study services, assay prototyping, assay characterization, and assay validation. The company was formerly known as BioProfile Corporation and changed its name to Singulex, Inc in September 2003. Singulex is based in Hayward, California

AirXpanders

Series D in 2012
AirXpanders develop technology enabling tissue expansion after reconstructive surgery with an emphasis on breast reconstruction. It addresses current unmet needs for patients who require tissue expansion after reconstructive surgery with the first emphasis on breast reconstruction. Present methods of tissue expansion utilize saline-filled implants that are typically injected on a weekly basis after surgery in order to reach the volume of skin and tissue required for the placement of a permanent breast implant.

The Nest Collective

Venture Round in 2012
The Nest Collective, Inc. produces organic food and snacks for babies, toddlers, and kids. The company was incorporated in 2008 and is based in Emeryville, California.

EndoStim

Venture Round in 2011
EndoStim, Inc., a medical device company, develops and commercializes neurostimulation solutions for the treatment of gastro-esophageal reflux disease (GERD). Its solutions cover treatment for GERD through electrical stimulation. The company distributes its products throughout Europe, Asia, and Latin America. EndoStim was founded in 2009 and is based in Dallas, Texas.
Veran Medical Technologies is an image-guided medical device company that helps physicians diagnose disease and deliver therapies. It develops a suite of products to enable physicians to diagnose disease and deliver therapies. It offers standards for minimally invasive delivery of interventional oncology therapies. The company provides plug-n-play delivery systems and navigated instruments. Its IG4 Platform allows clinicians to visualize various types of information integrated with a CT dataset, such as respiration, contrast-enhanced structures, PET, and ultrasound. The company also provides SPiN Drive System that acts as a GPS-like system to enable pulmonologists and surgeons to access peripheral solitary pulmonary nodules to diagnose malignancy. The company was incorporated in 2007 and is headquartered in St. Louis, Missouri.

Veniti

Series A in 2011
VENITI is the first medical device company developing a suite of innovative technology and solutions that will provide comprehensive treatment across the venous disease continuum. Venous disease refers to all conditions related to or caused by veins that become diseased or abnormal. This encompasses a broad set of maladies. The venous disease cycle begins when vein walls become weak or damaged, or the valves are stretched or injured, and can no longer prevent reflux (backward flow of blood). Once the veins lose their ability to convey blood without reflux, the progressive venous disease cycle has begun. This is commonly referred to as chronic venous insufficiency, or CVI. The blood will begin to back up into the peripheral veins, causing venous hypertension, potential thrombosis (clotting), and leading to even more damage of the vein walls and valves. This in turn leads to more reflux. The VENITI team of experts in science, technology and business are currently developing the VENITI VICI VENOUS STENT® System. Through this, and other, innovative technology, VENITI will achieve results that sets it apart in addressing the challenges specific to the venous system and venous disease.

EndoStim

Series B in 2010
EndoStim, Inc., a medical device company, develops and commercializes neurostimulation solutions for the treatment of gastro-esophageal reflux disease (GERD). Its solutions cover treatment for GERD through electrical stimulation. The company distributes its products throughout Europe, Asia, and Latin America. EndoStim was founded in 2009 and is based in Dallas, Texas.

Akermin

Series B in 2010
Akermin, Inc., a biocatalyst development company, develops a solution to remove carbon dioxide (CO2) from industrial gas streams using biocatalysis and nanotechnology. The company offers proprietary delivery systems to integrate enzymes into conventional processes for CO2 removal using chemical absorption. Its technology serves a range of industries and markets in the United States. The company was founded in 2003 and is based in St. Louis, Missouri.

Plum Organics

Series B in 2009
Plum Organics is a leading organic baby food and toddler snack brand in the nation. Building on the core values of healthy eating for life Plum Organics has created a line of culinary inspired baby foods in three stages that are gently cooked for optimal nutrition. From ingredient sourcing to packaging choices, Plum Organics is continually striving to reduce our carbon footprint and to ensure that our product line is pure and clean from the inside out. Plum Organics baby & tots snacks further build on these core values, by providing continued support with nutritious and simple solutions for on the go.

Divergence

Series C in 2009
Divergence is a research and development company dedicated to the discovery of effective and ecologically sound strategies for the control of parasites and other pests. The Company's initial focus is on parasitic nematodes, one of the world's major pest groups. Nematodes are roundworms that cause billions of dollars in damage annually to numerous crops, including soybeans, corn, cotton, strawberries, and bananas. Nematodes causing important human diseases include hookworm, whipworm, roundworm (Ascaris), and the filarial worms responsible for lymphatic filariasis and onchocerciasis.
Veran Medical Technologies is an image-guided medical device company that helps physicians diagnose disease and deliver therapies. It develops a suite of products to enable physicians to diagnose disease and deliver therapies. It offers standards for minimally invasive delivery of interventional oncology therapies. The company provides plug-n-play delivery systems and navigated instruments. Its IG4 Platform allows clinicians to visualize various types of information integrated with a CT dataset, such as respiration, contrast-enhanced structures, PET, and ultrasound. The company also provides SPiN Drive System that acts as a GPS-like system to enable pulmonologists and surgeons to access peripheral solitary pulmonary nodules to diagnose malignancy. The company was incorporated in 2007 and is headquartered in St. Louis, Missouri.

Asoyia

Venture Round in 2008
Asoyia, LLC produces soybeans and soybean oil. It serves food processors, institutional food management, and restaurant chains. The company offers its products through distributors. Asoyia, LLC was founded in 2004 and is based in Iowa City, Iowa. The company has locations in Des Moines and Cedar Rapids, Iowa; and Bloomington Illinois.

CS-Keys

Series A in 2008
CS-Keys is a private, Indianapolis-based biotechnology company focused on the discovery and development of 3rd generation cancer-associated biomarkers using proteomics. These biomarkers may be used to create products to enhance the diagnosis and treatment of patients with cancer.

Akermin

Series A in 2007
Akermin, Inc., a biocatalyst development company, develops a solution to remove carbon dioxide (CO2) from industrial gas streams using biocatalysis and nanotechnology. The company offers proprietary delivery systems to integrate enzymes into conventional processes for CO2 removal using chemical absorption. Its technology serves a range of industries and markets in the United States. The company was founded in 2003 and is based in St. Louis, Missouri.

Chlorogen

Venture Round in 2007
Chlorogen a biopharmaceutical company, engages in the development and manufacture of proteins for human therapy. The company, through its chloroplast transformation technology (CTT), offers plant made drugs for the treatment and prevention of human diseases, as well as for treatment of women's reproductive cancers. Its products include therapeutic proteins in tobacco that are made using chloroplast transformation technology. The chloroplast transformation technology facilitates hyper-expression of recombinant proteins in tobacco chloroplasts. The company offers its chloroplast-tobacco platform for commercial use in food and agriculture. Chlorogen, Inc. was founded in 2002 and is based in St. Louis, Missouri.

Singulex

Series D in 2007
Singulex, Inc., a biotechnology company, develops and commercializes direct molecular detection technology solutions. Its solutions enable life science researchers and clinicians to understand and manage disease. The company develops biomarker diagnostic systems that can detect and quantify normal and abnormal protein biomarkers. It is conducting pilot studies to validate Erenna BioAssay System, a digital molecule detection platform, which detects and quantifies molecule biomarkers in clinical samples. The company also offers various custom assay services, such as pilot study services, assay prototyping, assay characterization, and assay validation. The company was formerly known as BioProfile Corporation and changed its name to Singulex, Inc in September 2003. Singulex is based in Hayward, California

Dreamerz Foods

Series B in 2007
Dreamerz Foods, Inc. provides various natural sleep products. It offers natural sleep beverage, a dietary supplement in the form of an all-natural, creamy, and dairy-based functional sleep beverage. The company also provides chocolate pillows, soothing dairy products, and herbal fruit-flavored mix. It offers its products through stores and online shops. Dreamerz Foods, Inc. was founded in 2006 and is based in San Francisco, California.

Natural Dentist

Series B in 2007
As of February 23, 2010, The Natural Dentist, Inc. was acquired by Revive Personal Products Company. The company manufactures oral care products in the United States. It offers mouth rinses and toothpastes through stores and online retailers, as well as through phone. The company was formerly known as Woodstock Natural Products Inc and changed its name to The Natural Dentist, Inc. in 2005. The Natural Dentist, Inc. was founded in 1995 and is based in Medford, Massachusetts.

Attune Foods

Series B in 2007
Attune Foods, Inc. offers probiotic wellness bars. It offers wellness bars in various flavors, including dark chocolate, chocolate crisp, mint chocolate, and blueberry vanilla, as well as chewy chocolate, peanut butter and chocolate, mango peach, wild berry, strawberry bliss, and lemon crème. Attune Foods, Inc. was founded in 2006 and is headquartered in San Francisco, California.

AirXpanders

Series A in 2007
AirXpanders develop technology enabling tissue expansion after reconstructive surgery with an emphasis on breast reconstruction. It addresses current unmet needs for patients who require tissue expansion after reconstructive surgery with the first emphasis on breast reconstruction. Present methods of tissue expansion utilize saline-filled implants that are typically injected on a weekly basis after surgery in order to reach the volume of skin and tissue required for the placement of a permanent breast implant.

AirXpanders

Venture Round in 2006
AirXpanders develop technology enabling tissue expansion after reconstructive surgery with an emphasis on breast reconstruction. It addresses current unmet needs for patients who require tissue expansion after reconstructive surgery with the first emphasis on breast reconstruction. Present methods of tissue expansion utilize saline-filled implants that are typically injected on a weekly basis after surgery in order to reach the volume of skin and tissue required for the placement of a permanent breast implant.

Dreamerz Foods

Series A in 2006
Dreamerz Foods, Inc. provides various natural sleep products. It offers natural sleep beverage, a dietary supplement in the form of an all-natural, creamy, and dairy-based functional sleep beverage. The company also provides chocolate pillows, soothing dairy products, and herbal fruit-flavored mix. It offers its products through stores and online shops. Dreamerz Foods, Inc. was founded in 2006 and is based in San Francisco, California.

Natural Dentist

Series B in 2006
As of February 23, 2010, The Natural Dentist, Inc. was acquired by Revive Personal Products Company. The company manufactures oral care products in the United States. It offers mouth rinses and toothpastes through stores and online retailers, as well as through phone. The company was formerly known as Woodstock Natural Products Inc and changed its name to The Natural Dentist, Inc. in 2005. The Natural Dentist, Inc. was founded in 1995 and is based in Medford, Massachusetts.

Travanti Pharma

Series B in 2006
Travanti Pharma is a privately held corporation that designs, develops and markets innovative drug delivery platforms that improve the safety, compliance, effectiveness and ease of administration of medications, which are delivered into the body.

Singulex

Series C in 2006
Singulex, Inc., a biotechnology company, develops and commercializes direct molecular detection technology solutions. Its solutions enable life science researchers and clinicians to understand and manage disease. The company develops biomarker diagnostic systems that can detect and quantify normal and abnormal protein biomarkers. It is conducting pilot studies to validate Erenna BioAssay System, a digital molecule detection platform, which detects and quantifies molecule biomarkers in clinical samples. The company also offers various custom assay services, such as pilot study services, assay prototyping, assay characterization, and assay validation. The company was formerly known as BioProfile Corporation and changed its name to Singulex, Inc in September 2003. Singulex is based in Hayward, California

EraGen Biosciences

Series A in 2006
EraGen Biosciences, Inc., a biotechnology company, develops, manufactures, and markets molecular reagent products and software for research and clinical testing markets. The company offers molecular diagnostic assays for the early detection and monitoring of cancer, genetic, and infectious diseases, as well as for genetic-based conditions. Its products include molecular diagnostic tests, analyte specific reagents, in vitro diagnostic reagents, and research use only reagents; MultiCode-PLx Analysis Software that allows users to create customized templates for plate and assay layouts; and MultiCode-RTx Analysis Software, which enables users to create templates for quantitative and qualitative analyses. The company serves clinical laboratories and medical researchers. It sells its products through distributors in the United States and Canada. The company was founded as Sulfonics, Inc. in 1994 and changed its name to EraGen Biosciences, Inc. in 1999. EraGen Biosciences, Inc. is based in Madison, Wisconsin.

Akermin

Series A in 2005
Akermin, Inc., a biocatalyst development company, develops a solution to remove carbon dioxide (CO2) from industrial gas streams using biocatalysis and nanotechnology. The company offers proprietary delivery systems to integrate enzymes into conventional processes for CO2 removal using chemical absorption. Its technology serves a range of industries and markets in the United States. The company was founded in 2003 and is based in St. Louis, Missouri.

Kereos

Series B in 2005
Kereos, Inc. is a biopharmaceutical company based in Saint Louis, Missouri, specializing in the development of targeted molecular imaging agents and therapeutics aimed at detecting and treating cancer and cardiovascular diseases. Established in 1999, Kereos utilizes a nanoscale drug delivery technology that enhances the targeting and efficacy of various therapeutic compounds, including existing drugs, new candidates, and those that may be too toxic or fragile for conventional delivery methods. The company's product portfolio includes KER-1001, a cancer therapeutic that combines paclitaxel with a targeted nanodroplet, KER-1002, which integrates a natural anti-tumor agent, and KER-1003, known for its anti-angiogenic properties. Additionally, Kereos offers diagnostic solutions such as KER 0001, designed to detect angiogenesis. The company also collaborates with pharmaceutical and imaging firms to further develop its MRI agents and targeted chemotherapeutics for solid tumors and cardiovascular applications.

Chlorogen

Series B in 2005
Chlorogen a biopharmaceutical company, engages in the development and manufacture of proteins for human therapy. The company, through its chloroplast transformation technology (CTT), offers plant made drugs for the treatment and prevention of human diseases, as well as for treatment of women's reproductive cancers. Its products include therapeutic proteins in tobacco that are made using chloroplast transformation technology. The chloroplast transformation technology facilitates hyper-expression of recombinant proteins in tobacco chloroplasts. The company offers its chloroplast-tobacco platform for commercial use in food and agriculture. Chlorogen, Inc. was founded in 2002 and is based in St. Louis, Missouri.

Quick Study Radiology

Series C in 2005
Quick Study Radiology provides digital imaging solutions for community hospitals, radiology and oncology practices, and imaging centers. The company offers image and data archiving, and disaster recovery services; monitoring and security services; and networking and web distribution services. It also provides picture archiving and communication systems for community hospitals and other facilities, and radiology information systems to store, manage, and distribute patient’s data and imagery. Quick Study Radiology was founded in 1999 and is based in Saint Louis, Missouri.

Brand New Brands

Series A in 2005
Brand New Brands is a groundbreaking new company that brings together the entrepreneurial spirit of a start-up and the resources of an established corporation to create new foods and beverages that promote health and wellness. Brand New Brands uses a portfolio-based incubator model to develop and market the highest potential new functional food business opportunities for the U.S. marketplace. Core to their approach is the commitment to create food and beverage products that are efficacious (by medical standards), honest and transparent in their claims, and satisfying to eat or drink. By vetting and assessing the potential of scores of new product concepts, they take the most promising opportunities and fuse them with talented, passionate and proven entrepreneurial teams who turn ideas into thriving new ventures. They focus their efforts and resources by innovating “category-creating” brand platforms that are capable of crossing over from niche markets to the mainstream in three to five years. They only pursue opportunities where they can claim distinct competitive advantages over large food companies through IP, brand creation or non-traditional distribution. Their strategy is to take the most promising new nutritional technologies and deliver them to the marketplace through great-tasting products with engaging “lifestyle” brands that educate and attract loyal customers and progressive retail partners. They take opportunities to market that are likely to scale quickly due to the convergence of scientific advances, consumer readiness and media attention.

Travanti Pharma

Series A in 2005
Travanti Pharma is a privately held corporation that designs, develops and markets innovative drug delivery platforms that improve the safety, compliance, effectiveness and ease of administration of medications, which are delivered into the body.

Zystor

Series A in 2004
ZyStor Therapeutics, Inc. is a privately-held biotechnology company developing enzyme replacement therapies for the treatment of lysosomal storage diseases.

Quick Study Radiology

Series C in 2004
Quick Study Radiology provides digital imaging solutions for community hospitals, radiology and oncology practices, and imaging centers. The company offers image and data archiving, and disaster recovery services; monitoring and security services; and networking and web distribution services. It also provides picture archiving and communication systems for community hospitals and other facilities, and radiology information systems to store, manage, and distribute patient’s data and imagery. Quick Study Radiology was founded in 1999 and is based in Saint Louis, Missouri.

Efficas

Series A in 2004
Efficas Medical Foods & Nutrition, LLC is a health-science and technology company focused on researching, developing, and commercializing products aimed at the nutritional management of the immune system for both humans and pets. The company offers Efficas Care, a berry-flavored non-prescription medical food designed to help manage asthma and associated allergies. Established in 2010 and based in Fullerton, California, Efficas is committed to providing effective nutritional solutions to enhance health and well-being.

Divergence

Venture Round in 2004
Divergence is a research and development company dedicated to the discovery of effective and ecologically sound strategies for the control of parasites and other pests. The Company's initial focus is on parasitic nematodes, one of the world's major pest groups. Nematodes are roundworms that cause billions of dollars in damage annually to numerous crops, including soybeans, corn, cotton, strawberries, and bananas. Nematodes causing important human diseases include hookworm, whipworm, roundworm (Ascaris), and the filarial worms responsible for lymphatic filariasis and onchocerciasis.

Chlorogen

Series A in 2003
Chlorogen a biopharmaceutical company, engages in the development and manufacture of proteins for human therapy. The company, through its chloroplast transformation technology (CTT), offers plant made drugs for the treatment and prevention of human diseases, as well as for treatment of women's reproductive cancers. Its products include therapeutic proteins in tobacco that are made using chloroplast transformation technology. The chloroplast transformation technology facilitates hyper-expression of recombinant proteins in tobacco chloroplasts. The company offers its chloroplast-tobacco platform for commercial use in food and agriculture. Chlorogen, Inc. was founded in 2002 and is based in St. Louis, Missouri.

Divergence

Venture Round in 2002
Divergence is a research and development company dedicated to the discovery of effective and ecologically sound strategies for the control of parasites and other pests. The Company's initial focus is on parasitic nematodes, one of the world's major pest groups. Nematodes are roundworms that cause billions of dollars in damage annually to numerous crops, including soybeans, corn, cotton, strawberries, and bananas. Nematodes causing important human diseases include hookworm, whipworm, roundworm (Ascaris), and the filarial worms responsible for lymphatic filariasis and onchocerciasis.

Inoveon

Series B in 2002
Inoveon Corporation is a medical services company that delivers solutions to detect, and stage and monitor diseases affecting the eye, diabetic retinopathy, macular degeneration, and glaucoma. The company offers iScan that detects and evaluates diabetic retinopathy and macular edema; INOVEON System, which works with physician groups to improve DR compliance rates. Inoveon Corporation was founded in 1997 and is based in Oklahoma City, Oklahoma. As of November 18, 2010, Inoveon Corporation operates as a subsidiary of Ifa Systems Ag.