Onset V

Onset Ventures was a private equity and venture capital firm based in Menlo Park, California, founded in 1984 by David Kelley, Michael Levinthal, and Terry Opdendyk. The firm focused on early-stage investments in the healthcare and technology sectors, particularly in areas such as software, medical devices, drug delivery, and diagnostics. Over the years, Onset Ventures targeted a diverse range of industries, including media, infrastructure software, and mobile technology. However, as of November 27, 2023, the firm has dissolved, concluding its operations in the investment landscape.

Robert F. Kuhling

General Partner, Managing Director and Member of Investing and Operation staff

Steve LaPorte

Venture Partner, Medical Technology

Ken Martin

Venture Associate

Terry Opdendyk

Founder, General Partner and Member of the Investment Team

Beatrice Pezino

Vice President of Finance

132 past transactions

Imanis Data

Series B in 2018
Imanis Data is a venture-backed startup based in Silicon Valley, currently operating in stealth mode. The company focuses on developing a next-generation data management platform aimed at transforming the big data and storage industry. With a team that possesses extensive expertise in storage and big data, Imanis Data is working on innovative solutions for fast data backup and recovery. The company is expected to reveal more about its groundbreaking products and developments as it transitions out of stealth mode.

Nok Nok

Series D in 2017
Nok Nok Labs, Inc. develops products and services for online security and authentication. Its products include Multifactor Authentication Client Desktop Edition that provides authentication to various applications by unleashing the existing security capabilities of desktops and laptops; and Multifactor Authentication Client Mobile Edition that enables users to authenticate to various applications using the existing security capabilities of their mobile devices. The company’s products also comprises Multifactor Authentication Server that provides an authentication infrastructure, which enables authentication for various devices, methods, and applications; and Nok Nok application SDK, a FIDO-based authentication solution for smart watch devices. Nok Nok Labs, Inc. has a strategic partnership with Synaptics. Nok Nok Labs, Inc. was formerly known as Facilisys Inc. The company was founded in 2011 and is based in Palo Alto, California.

Vertos Medical

Venture Round in 2017
Vertos Medical Inc. is a medical device company based in Aliso Viejo, California, founded in 2005 by Dr. Dave Solsberg and Dr. Don Schomer. The company specializes in developing minimally invasive treatments for lumbar spinal stenosis (LSS), a common spinal condition. Its flagship product, the mild device, facilitates an outpatient treatment that is fluoroscopically guided and does not require the use of implants. This device includes components such as tissue sculptors, portals, trocars, and surgical clamps, allowing physicians to perform lumbar decompression procedures with local anesthesia. By restoring space in the spinal canal and alleviating pressure on the nerves, Vertos Medical's solutions aim to improve patient mobility and quality of life. The company's devices are primarily offered in the United States.

Neuronetics

Series G in 2017
Neuronetics is a medical technology company based in Malvern, Pennsylvania, established in 2003. It specializes in developing non-invasive therapies for psychiatric and neurological disorders, particularly Major Depressive Disorder (MDD). The company's flagship product, the NeuroStar Advanced Therapy System, utilizes transcranial magnetic stimulation (TMS) to deliver MRI-strength magnetic pulses that induce electrical currents in targeted areas of the brain associated with mood regulation. This innovative treatment is the first of its kind to receive FDA clearance for patients who have not found relief from traditional antidepressant therapies. Neuronetics aims to improve the quality of life for individuals suffering from mental health conditions through its advanced, non-systemic treatment options.

Apama Medical

Series C in 2016
Apama Medical, Inc. manufactures catheter ablation technology devices for the treatment of atrial fibrillation (AF). Its product, include Apama radiofrequency (RF) balloon catheter system, a single-shot, multi-electrode technology which is designed to combine the benefits of both RF point-by-point and balloon-based ablation approaches. Its technology incorporates built-in digital cameras with LED lights and sensing electrodes on the balloon which allow for real-time visualization and assessment of catheter electrode contact. The company was incorporated in 2009 and is based in Campbell, California. As of October 10, 2017, Apama Medical, Inc. operates as a subsidiary of Boston Scientific Corporation.

Gridstore

Series B in 2016
Gridstore™ is the leader in HyperConverged All-Flash Infrastructure for the Microsoft Cloud-Inspired Data Center. Our customers gain a 10X performance improvement over traditional storage as we put all-flash as close to the workload as possible. They realize 4X lower TCO by consolidation of three layers of infrastructure into one scalable layer built on X86 hardware and 10X less management effort due to less management points and less infrastructure to manage. Gridstore's HyperConverged Appliances include both compute and storage in a single system, and provide external storage and work with any Windows servers and the HyperConverged Appliance, all driven by Gridstore's patented software. Gridstore software architecture delivers native Windows integration, per-VM I/O control, and elastic and independent scaling of resources. Gridstore is headquartered in Mountain View, CA. and its products and services are available through a global network of value-added resellers.

BAROnova

Series D in 2015
BAROnova, Inc. is a clinical-stage medical-device company founded in 2006 and based in Goleta, California. The company specializes in developing non-surgical and non-pharmacologic devices aimed at inducing weight loss. Its primary product, the TransPyloric Shuttle, is designed to be inserted into the stomach through the mouth via a simple endoscopic procedure. This device helps patients feel full more quickly, prolongs the sensation of fullness, and delays gastric emptying, thereby supporting weight loss efforts.

Polymorph

Series A in 2015
Polymorph powers the monetization infrastructure for modern enterprises. Polymorph is a white-label SaaS monetization platform for publishers to maximize revenue, reduce costs and deliver better ad experiences.The Polymorph platform offers end-to-end ad serving stack, yield optimization tools, APIs, access to demand on server-side and self-serve workflows. Modern enterprises who want to monetize with advertising choose our customizable and developer friendly platform as it aligns with their needs/strategies. The company was founded in 2013 and is based in San Francisco, California.

Adara

Series C in 2015
Adara, the global leader in permissioned data and verified identity, combines the power of global data consortiums to inform its 1 billion digital identities with over 22 billion data elements across 130 countries and serving Global 2,000 customers. Whether informing digital marketing, programmatic advertising, search, identity and verification, or stopping fraud, Adara provides you with more customers, less friction, and better outcomes. For more information, visit us at www.ADARA.com.

Nok Nok

Series C in 2015
Nok Nok Labs, Inc. develops products and services for online security and authentication. Its products include Multifactor Authentication Client Desktop Edition that provides authentication to various applications by unleashing the existing security capabilities of desktops and laptops; and Multifactor Authentication Client Mobile Edition that enables users to authenticate to various applications using the existing security capabilities of their mobile devices. The company’s products also comprises Multifactor Authentication Server that provides an authentication infrastructure, which enables authentication for various devices, methods, and applications; and Nok Nok application SDK, a FIDO-based authentication solution for smart watch devices. Nok Nok Labs, Inc. has a strategic partnership with Synaptics. Nok Nok Labs, Inc. was formerly known as Facilisys Inc. The company was founded in 2011 and is based in Palo Alto, California.

Imanis Data

Series A in 2015
Imanis Data is a venture-backed startup based in Silicon Valley, currently operating in stealth mode. The company focuses on developing a next-generation data management platform aimed at transforming the big data and storage industry. With a team that possesses extensive expertise in storage and big data, Imanis Data is working on innovative solutions for fast data backup and recovery. The company is expected to reveal more about its groundbreaking products and developments as it transitions out of stealth mode.

Adaptive Insights

Series G in 2015
Adaptive Insights, Inc. specializes in integrated cloud-based corporate performance management (CPM) and business intelligence (BI) solutions. The company offers a suite of products designed to enhance business planning and financial consolidation, including Adaptive Suite, Adaptive Planning, and Adaptive Consolidation. These tools facilitate intuitive planning, forecasting, reporting, and dashboards that enable organizations to streamline their financial processes. Additionally, Adaptive Insights provides solutions for workforce and expense management, capital management, and profitability analysis, among others. The company is recognized for its user-friendly interface and has received high customer satisfaction ratings in industry surveys. Serving a diverse range of sectors, including healthcare, retail, financial services, and manufacturing, Adaptive Insights empowers organizations to make informed decisions and improve their business agility. Founded in 2003 and headquartered in Palo Alto, California, the company operates as a subsidiary of Workday, Inc.

Neuronetics

Series F in 2015
Neuronetics is a medical technology company based in Malvern, Pennsylvania, established in 2003. It specializes in developing non-invasive therapies for psychiatric and neurological disorders, particularly Major Depressive Disorder (MDD). The company's flagship product, the NeuroStar Advanced Therapy System, utilizes transcranial magnetic stimulation (TMS) to deliver MRI-strength magnetic pulses that induce electrical currents in targeted areas of the brain associated with mood regulation. This innovative treatment is the first of its kind to receive FDA clearance for patients who have not found relief from traditional antidepressant therapies. Neuronetics aims to improve the quality of life for individuals suffering from mental health conditions through its advanced, non-systemic treatment options.

Vidder

Series B in 2015
Vidder is a cybersecurity company based in Campbell, California, specializing in access control solutions that enhance network security. Established in 2009, Vidder's technology is centered around the Software-Defined Perimeter (SDP) standard, which aims to mitigate network-based attacks by rendering servers invisible to unauthorized users. The company's offerings include managed services that safeguard valuable networked assets while ensuring pre-authenticated, context-aware access to enterprise applications. By focusing on blocking connectivity from unknown devices, Vidder provides organizations with a robust defense against cyber threats, thereby reducing security risks associated with their digital infrastructure.

Apama Medical

Series B in 2015
Apama Medical, Inc. manufactures catheter ablation technology devices for the treatment of atrial fibrillation (AF). Its product, include Apama radiofrequency (RF) balloon catheter system, a single-shot, multi-electrode technology which is designed to combine the benefits of both RF point-by-point and balloon-based ablation approaches. Its technology incorporates built-in digital cameras with LED lights and sensing electrodes on the balloon which allow for real-time visualization and assessment of catheter electrode contact. The company was incorporated in 2009 and is based in Campbell, California. As of October 10, 2017, Apama Medical, Inc. operates as a subsidiary of Boston Scientific Corporation.

ClariPhy Communications

Venture Round in 2014
ClariPhy Communications, Inc. is a semiconductor company specializing in mixed-signal integrated circuits designed for optical networking and communication applications. Founded in 2002 and headquartered in Irvine, California, with an additional office in Los Altos, the company develops advanced digital signal processing system-on-chips that cater to high-performance optical network needs. Its product lineup includes coherent single chip transceivers and system-on-chips, which are utilized in various markets such as data centers, transport infrastructure, enterprise networks, and telecom applications. ClariPhy’s technology supports multi-mode and multi-rate operations, making it suitable for metro, long haul, and ultra-long haul communications. The company primarily serves original equipment manufacturers of networking devices, providing solutions that enhance performance, bandwidth, and cost efficiency in data and telecom networks. As of December 2016, ClariPhy operates as a subsidiary of Inphi Corporation.

Valeritas

Series D in 2014
On June 30, 2020, Valeritas Holdings, Inc. went out of business as per its Chapter 11 liquidation filing under bankruptcy. Valeritas Holdings, Inc., a commercial-stage medical technology company, focuses on the development and commercialization of technologies to treat patients with Type 2 diabetes in the United States. The company offers V-Go, a wearable insulin delivery device for basal-bolus therapy. It also develops V-Go Prefill that is in the design-development stage for eliminating the device-filling process and the need for EZ fill refrigeration for patients with Type 2 diabetes; and V-Go SIM for real-time tracking information of basal and bolus dosing utilization. The company sells V-Go to third-party wholesalers and medical supply distributors. Valeritas Holdings, Inc. was founded in 2006 and is headquartered in Bridgewater, New Jersey.

Polymorph

Seed Round in 2014
Polymorph powers the monetization infrastructure for modern enterprises. Polymorph is a white-label SaaS monetization platform for publishers to maximize revenue, reduce costs and deliver better ad experiences.The Polymorph platform offers end-to-end ad serving stack, yield optimization tools, APIs, access to demand on server-side and self-serve workflows. Modern enterprises who want to monetize with advertising choose our customizable and developer friendly platform as it aligns with their needs/strategies. The company was founded in 2013 and is based in San Francisco, California.

Nok Nok

Series B in 2014
Nok Nok Labs, Inc. develops products and services for online security and authentication. Its products include Multifactor Authentication Client Desktop Edition that provides authentication to various applications by unleashing the existing security capabilities of desktops and laptops; and Multifactor Authentication Client Mobile Edition that enables users to authenticate to various applications using the existing security capabilities of their mobile devices. The company’s products also comprises Multifactor Authentication Server that provides an authentication infrastructure, which enables authentication for various devices, methods, and applications; and Nok Nok application SDK, a FIDO-based authentication solution for smart watch devices. Nok Nok Labs, Inc. has a strategic partnership with Synaptics. Nok Nok Labs, Inc. was formerly known as Facilisys Inc. The company was founded in 2011 and is based in Palo Alto, California.

Gridstore

Series B in 2013
Gridstore™ is the leader in HyperConverged All-Flash Infrastructure for the Microsoft Cloud-Inspired Data Center. Our customers gain a 10X performance improvement over traditional storage as we put all-flash as close to the workload as possible. They realize 4X lower TCO by consolidation of three layers of infrastructure into one scalable layer built on X86 hardware and 10X less management effort due to less management points and less infrastructure to manage. Gridstore's HyperConverged Appliances include both compute and storage in a single system, and provide external storage and work with any Windows servers and the HyperConverged Appliance, all driven by Gridstore's patented software. Gridstore software architecture delivers native Windows integration, per-VM I/O control, and elastic and independent scaling of resources. Gridstore is headquartered in Mountain View, CA. and its products and services are available through a global network of value-added resellers.

Adaptive Insights

Series F in 2013
Adaptive Insights, Inc. specializes in integrated cloud-based corporate performance management (CPM) and business intelligence (BI) solutions. The company offers a suite of products designed to enhance business planning and financial consolidation, including Adaptive Suite, Adaptive Planning, and Adaptive Consolidation. These tools facilitate intuitive planning, forecasting, reporting, and dashboards that enable organizations to streamline their financial processes. Additionally, Adaptive Insights provides solutions for workforce and expense management, capital management, and profitability analysis, among others. The company is recognized for its user-friendly interface and has received high customer satisfaction ratings in industry surveys. Serving a diverse range of sectors, including healthcare, retail, financial services, and manufacturing, Adaptive Insights empowers organizations to make informed decisions and improve their business agility. Founded in 2003 and headquartered in Palo Alto, California, the company operates as a subsidiary of Workday, Inc.

Adara

Series B in 2013
Adara, the global leader in permissioned data and verified identity, combines the power of global data consortiums to inform its 1 billion digital identities with over 22 billion data elements across 130 countries and serving Global 2,000 customers. Whether informing digital marketing, programmatic advertising, search, identity and verification, or stopping fraud, Adara provides you with more customers, less friction, and better outcomes. For more information, visit us at www.ADARA.com.

BAROnova

Series C in 2013
BAROnova, Inc. is a clinical-stage medical-device company founded in 2006 and based in Goleta, California. The company specializes in developing non-surgical and non-pharmacologic devices aimed at inducing weight loss. Its primary product, the TransPyloric Shuttle, is designed to be inserted into the stomach through the mouth via a simple endoscopic procedure. This device helps patients feel full more quickly, prolongs the sensation of fullness, and delays gastric emptying, thereby supporting weight loss efforts.

Nok Nok

Series A in 2013
Nok Nok Labs, Inc. develops products and services for online security and authentication. Its products include Multifactor Authentication Client Desktop Edition that provides authentication to various applications by unleashing the existing security capabilities of desktops and laptops; and Multifactor Authentication Client Mobile Edition that enables users to authenticate to various applications using the existing security capabilities of their mobile devices. The company’s products also comprises Multifactor Authentication Server that provides an authentication infrastructure, which enables authentication for various devices, methods, and applications; and Nok Nok application SDK, a FIDO-based authentication solution for smart watch devices. Nok Nok Labs, Inc. has a strategic partnership with Synaptics. Nok Nok Labs, Inc. was formerly known as Facilisys Inc. The company was founded in 2011 and is based in Palo Alto, California.

Gridstore

Series A in 2012
Gridstore™ is the leader in HyperConverged All-Flash Infrastructure for the Microsoft Cloud-Inspired Data Center. Our customers gain a 10X performance improvement over traditional storage as we put all-flash as close to the workload as possible. They realize 4X lower TCO by consolidation of three layers of infrastructure into one scalable layer built on X86 hardware and 10X less management effort due to less management points and less infrastructure to manage. Gridstore's HyperConverged Appliances include both compute and storage in a single system, and provide external storage and work with any Windows servers and the HyperConverged Appliance, all driven by Gridstore's patented software. Gridstore software architecture delivers native Windows integration, per-VM I/O control, and elastic and independent scaling of resources. Gridstore is headquartered in Mountain View, CA. and its products and services are available through a global network of value-added resellers.

Access Closure

Venture Round in 2012
Access Closure, Inc. is a medical device company based in Mountain View, California, specializing in access site management products that facilitate vascular closure during interventional and diagnostic procedures. Founded in 2002, the company is known for its Mynx delivery system, a vascular closure device that employs a water-soluble, extravascular sealant. This innovative sealant expands within the tissue tract by absorbing blood and subcutaneous fluids, effectively sealing the arteriotomy. Access Closure aims to simplify the complex challenges associated with vascular closure, thereby enhancing patient outcomes during medical procedures.

Cloud Cruiser

Series B in 2012
Cloud Cruiser, Inc. provides software solutions that enable businesses to efficiently manage their cloud financial operations. Founded in 2010 and based in San Jose, California, the company specializes in a cloud financial management solution that automates the collection and aggregation of IT costs and revenues across various environments, including public clouds, private clouds, and traditional IT setups. Its software offers features such as self-service cloud billing, hybrid IT show back and chargeback capabilities, and granular profit and loss analytics. These tools allow enterprises and service providers to optimize costs and gain comprehensive visibility into their cloud usage and expenditures. In January 2017, Cloud Cruiser became a subsidiary of Hewlett Packard Enterprise Company.

Relievant

Series D in 2012
Relievant Medsystems, Inc. is a medical device company focused on addressing chronic axial low back pain through a minimally invasive procedure known as Intracept. This innovative treatment specifically targets the basivertebral nerve, utilizing radio-frequency energy delivered through a small access tube into the vertebral body to ablate the nerve. The procedure is performed under real-time fluoroscopic guidance, ensuring precision and safety. Founded in 2004 and headquartered in Minneapolis, Minnesota, with an additional office in Sunnyvale, California, Relievant aims to provide low-risk therapeutic solutions that significantly improve the quality of life for patients suffering from vertebrogenic low back pain.

Buysight

Series B in 2012
Buysight, formerly known as Permuto, aims to enhance the reach, performance, and measurability of display advertising, similar to search engine marketing. The company offers effective solutions tailored for both brand and performance advertisers, leveraging its proprietary online display advertising network, ShopperConnect™, which targets the expansive online e-commerce shopping market. Founded by industry veterans with experience from major tech companies, Buysight is positioned to innovate within the digital advertising landscape, providing valuable tools for advertisers seeking to optimize their campaigns.

Adaptive Insights

Series E in 2012
Adaptive Insights, Inc. specializes in integrated cloud-based corporate performance management (CPM) and business intelligence (BI) solutions. The company offers a suite of products designed to enhance business planning and financial consolidation, including Adaptive Suite, Adaptive Planning, and Adaptive Consolidation. These tools facilitate intuitive planning, forecasting, reporting, and dashboards that enable organizations to streamline their financial processes. Additionally, Adaptive Insights provides solutions for workforce and expense management, capital management, and profitability analysis, among others. The company is recognized for its user-friendly interface and has received high customer satisfaction ratings in industry surveys. Serving a diverse range of sectors, including healthcare, retail, financial services, and manufacturing, Adaptive Insights empowers organizations to make informed decisions and improve their business agility. Founded in 2003 and headquartered in Palo Alto, California, the company operates as a subsidiary of Workday, Inc.

Uptake Medical

Series C in 2012
Uptake Medical specializes in developing innovative medical technologies aimed at treating lung diseases. The company's flagship product, InterVapor™, is an endoscopic lung volume reduction therapy designed specifically for individuals with severe emphysema. This unique approach leverages the body’s natural healing processes and does not introduce any foreign materials into the lungs. Clinical studies have shown that InterVapor™ can lead to significant improvements in patients' breathing function, exercise capacity, and overall quality of life.

Adara

Venture Round in 2012
Adara, the global leader in permissioned data and verified identity, combines the power of global data consortiums to inform its 1 billion digital identities with over 22 billion data elements across 130 countries and serving Global 2,000 customers. Whether informing digital marketing, programmatic advertising, search, identity and verification, or stopping fraud, Adara provides you with more customers, less friction, and better outcomes. For more information, visit us at www.ADARA.com.

CytoPherx

Series C in 2012
CytoPherx (formerly Nephrion) clinical stage medical device company addressing inflammation-based diseases and conditions. The company’s products are custom configurations of a proprietary selective cytopheresis-based inflammation modulating system.

Flexuspine

Series B in 2011
Flexuspine operates as a spine company. It offers a spinal segment replacement to provide an alternative to lumbar fusion by re-establishing mobility to an affected segment of the lumbar spine. The company’s functional spinal unit is a comprehensive device composed of an interbody disc component and posterior dynamic resistance component to replace the natural kinematics of the motion segment. Flexuspine was founded on 2003 and is based in Pittsburgh, Pennsylvania.

Valeritas

Series C in 2011
On June 30, 2020, Valeritas Holdings, Inc. went out of business as per its Chapter 11 liquidation filing under bankruptcy. Valeritas Holdings, Inc., a commercial-stage medical technology company, focuses on the development and commercialization of technologies to treat patients with Type 2 diabetes in the United States. The company offers V-Go, a wearable insulin delivery device for basal-bolus therapy. It also develops V-Go Prefill that is in the design-development stage for eliminating the device-filling process and the need for EZ fill refrigeration for patients with Type 2 diabetes; and V-Go SIM for real-time tracking information of basal and bolus dosing utilization. The company sells V-Go to third-party wholesalers and medical supply distributors. Valeritas Holdings, Inc. was founded in 2006 and is headquartered in Bridgewater, New Jersey.

Sentilla

Series C in 2011
Sentilla, based in Redwood City, California, specializes in data center management and IT intelligence infrastructure. The company provides a software solution that enhances visibility across physical, virtual, and cloud environments, enabling enterprises to optimize their IT resource utilization and align it with business needs. By offering services such as performance analysis, capacity management, and cloud migration, Sentilla aids clients in minimizing risks and improving infrastructure performance continually. Its software is utilized by global enterprises, including cloud service providers and telecommunications companies, to achieve significant efficiency gains, with clients reportedly realizing $1.40 for every dollar invested in IT. The company’s focus on reducing capital and operational expenditures allows businesses to deploy resources more quickly and enter new markets with agility.

ClariPhy Communications

Series C in 2011
ClariPhy Communications, Inc. is a semiconductor company specializing in mixed-signal integrated circuits designed for optical networking and communication applications. Founded in 2002 and headquartered in Irvine, California, with an additional office in Los Altos, the company develops advanced digital signal processing system-on-chips that cater to high-performance optical network needs. Its product lineup includes coherent single chip transceivers and system-on-chips, which are utilized in various markets such as data centers, transport infrastructure, enterprise networks, and telecom applications. ClariPhy’s technology supports multi-mode and multi-rate operations, making it suitable for metro, long haul, and ultra-long haul communications. The company primarily serves original equipment manufacturers of networking devices, providing solutions that enhance performance, bandwidth, and cost efficiency in data and telecom networks. As of December 2016, ClariPhy operates as a subsidiary of Inphi Corporation.

Neuronetics

Series E in 2011
Neuronetics is a medical technology company based in Malvern, Pennsylvania, established in 2003. It specializes in developing non-invasive therapies for psychiatric and neurological disorders, particularly Major Depressive Disorder (MDD). The company's flagship product, the NeuroStar Advanced Therapy System, utilizes transcranial magnetic stimulation (TMS) to deliver MRI-strength magnetic pulses that induce electrical currents in targeted areas of the brain associated with mood regulation. This innovative treatment is the first of its kind to receive FDA clearance for patients who have not found relief from traditional antidepressant therapies. Neuronetics aims to improve the quality of life for individuals suffering from mental health conditions through its advanced, non-systemic treatment options.
VisionCare Ophthalmic Technologies, Inc. is a specialty medical device company based in Saratoga, California, focused on the research, development, manufacture, and marketing of innovative implantable ophthalmic devices. The company primarily aims to enhance vision and quality of life for individuals suffering from untreatable retinal disorders, particularly end-stage age-related macular degeneration (AMD), which is a leading cause of blindness among older Americans. VisionCare's flagship product is the Implantable Miniature Telescope, the first FDA-approved device designed to improve vision in patients with advanced AMD. This telescope implant is a critical component of the CentraSight treatment program, which guides patients through the processes of diagnosis, surgical evaluation, and postoperative care. Founded in 1997, VisionCare is dedicated to helping patients reconnect with their daily lives and activities through its advanced visual prosthetic technologies.

SS8 Networks

Series B in 2010
SS8 Networks, Inc. specializes in network compliance solutions for communications providers globally. The company offers a range of products, including Xcipio, a mediation tool for lawful intercept that connects telecommunications networks with governmental and law enforcement agencies; BreachDetect, a data breach detection solution; and Intellego, an application for real-time monitoring of criminal internet communications. SS8 also provides the Xcipio Probe, which accesses communication content from complex network architectures, featuring high-performance keyword search and security capabilities. The company's technology enables clients to identify, track, and investigate suspects and devices of interest by analyzing extensive records from network packets. SS8 serves a diverse clientele, including law enforcement agencies, telecommunications providers, and national governments. Founded in 1999, the company is headquartered in Milpitas, California.

Vindicia

Series E in 2010
Vindicia offers comprehensive subscription management solutions that help businesses acquire and retain more customers. Providing much more than just a billing and payments system, the company’s SaaS-based subscription management platform combines big data analysis, strategic consulting and proprietary retention technology. Vindicia provides its clients with more recurring revenue, more customer data, better insights, and greater value throughout the entire subscriber lifecycle.

Buysight

Series A in 2010
Buysight, formerly known as Permuto, aims to enhance the reach, performance, and measurability of display advertising, similar to search engine marketing. The company offers effective solutions tailored for both brand and performance advertisers, leveraging its proprietary online display advertising network, ShopperConnect™, which targets the expansive online e-commerce shopping market. Founded by industry veterans with experience from major tech companies, Buysight is positioned to innovate within the digital advertising landscape, providing valuable tools for advertisers seeking to optimize their campaigns.

Uptake Medical

Series B in 2010
Uptake Medical specializes in developing innovative medical technologies aimed at treating lung diseases. The company's flagship product, InterVapor™, is an endoscopic lung volume reduction therapy designed specifically for individuals with severe emphysema. This unique approach leverages the body’s natural healing processes and does not introduce any foreign materials into the lungs. Clinical studies have shown that InterVapor™ can lead to significant improvements in patients' breathing function, exercise capacity, and overall quality of life.

ClariPhy Communications

Series C in 2010
ClariPhy Communications, Inc. is a semiconductor company specializing in mixed-signal integrated circuits designed for optical networking and communication applications. Founded in 2002 and headquartered in Irvine, California, with an additional office in Los Altos, the company develops advanced digital signal processing system-on-chips that cater to high-performance optical network needs. Its product lineup includes coherent single chip transceivers and system-on-chips, which are utilized in various markets such as data centers, transport infrastructure, enterprise networks, and telecom applications. ClariPhy’s technology supports multi-mode and multi-rate operations, making it suitable for metro, long haul, and ultra-long haul communications. The company primarily serves original equipment manufacturers of networking devices, providing solutions that enhance performance, bandwidth, and cost efficiency in data and telecom networks. As of December 2016, ClariPhy operates as a subsidiary of Inphi Corporation.

Placecast

Series B in 2010
Placecast is a leading enterprise mobile data management platform that integrates carrier data, location data, and user behavior across multiple devices to enhance marketing strategies. By utilizing its comprehensive suite of products, advertisers can develop custom audience segments and implement location-enabled mobile ad campaigns. Placecast's platform also allows for the evaluation of campaign accuracy and its impact on customer behavior. The company has established over 400 million unique mobile user profiles, drawing from billions of data attributes, and has earned the trust of major global enterprises. Renowned brands such as Starbucks, Gap, JetBlue, and Subway have utilized Placecast to create more tailored mobile experiences for their target audiences. Founded in 2005 and headquartered in San Francisco, with additional offices in Atlanta, New York, and London, Placecast is supported by Voyager Capital and Onset Ventures.

Vertos Medical

Series D in 2010
Vertos Medical Inc. is a medical device company based in Aliso Viejo, California, founded in 2005 by Dr. Dave Solsberg and Dr. Don Schomer. The company specializes in developing minimally invasive treatments for lumbar spinal stenosis (LSS), a common spinal condition. Its flagship product, the mild device, facilitates an outpatient treatment that is fluoroscopically guided and does not require the use of implants. This device includes components such as tissue sculptors, portals, trocars, and surgical clamps, allowing physicians to perform lumbar decompression procedures with local anesthesia. By restoring space in the spinal canal and alleviating pressure on the nerves, Vertos Medical's solutions aim to improve patient mobility and quality of life. The company's devices are primarily offered in the United States.

Pancetera

Series A in 2009
Pancetera is a provider of system and storage management solutions tailored for virtualized server environments. The company aims to simplify the complexities and reduce costs associated with data protection and management in virtual settings. By offering a virtual appliance, Pancetera enhances performance, minimizes resource contention, and lowers the cost per virtual machine. The leadership team comprises experienced professionals from notable companies in the industry, including Data Domain, Legato, and Thinstall.

Placecast

Series B in 2009
Placecast is a leading enterprise mobile data management platform that integrates carrier data, location data, and user behavior across multiple devices to enhance marketing strategies. By utilizing its comprehensive suite of products, advertisers can develop custom audience segments and implement location-enabled mobile ad campaigns. Placecast's platform also allows for the evaluation of campaign accuracy and its impact on customer behavior. The company has established over 400 million unique mobile user profiles, drawing from billions of data attributes, and has earned the trust of major global enterprises. Renowned brands such as Starbucks, Gap, JetBlue, and Subway have utilized Placecast to create more tailored mobile experiences for their target audiences. Founded in 2005 and headquartered in San Francisco, with additional offices in Atlanta, New York, and London, Placecast is supported by Voyager Capital and Onset Ventures.

Neuronetics

Series D in 2009
Neuronetics is a medical technology company based in Malvern, Pennsylvania, established in 2003. It specializes in developing non-invasive therapies for psychiatric and neurological disorders, particularly Major Depressive Disorder (MDD). The company's flagship product, the NeuroStar Advanced Therapy System, utilizes transcranial magnetic stimulation (TMS) to deliver MRI-strength magnetic pulses that induce electrical currents in targeted areas of the brain associated with mood regulation. This innovative treatment is the first of its kind to receive FDA clearance for patients who have not found relief from traditional antidepressant therapies. Neuronetics aims to improve the quality of life for individuals suffering from mental health conditions through its advanced, non-systemic treatment options.

Brilliant Telecommunications

Venture Round in 2009
Brilliant Telecommunications, Inc. designs, develops, and distributes network timing, management, and synchronization solutions. Its products include Zurich Z-1000, a zero footprint, outdoor, and pole-mounted Network Time Protocol server that embodies its own timing management interface to provide tools for diagnosis, monitoring, and alarms; Cern C-2000, which is a Primary Reference Source and Clock that provides time stamping accuracy and configurability; and BT-750, a network timing client that delivers multiple synchronous outputs in a flexible platform. The company serves financial markets, legal institutions, telecommunication companies, and manufacturing organizations. Brilliant Telecommunications, Inc. was founded in 2004 and is based in Campbell, California.

PacketMotion

Series C in 2009
PacketMotion, Inc. specializes in developing security solutions that help enterprises monitor user activity within their networks. The company's primary offering is the PacketSentry appliance, which allows organizations to track user behavior across server and application platforms. In addition to its core product, PacketMotion provides a range of services such as installation, training, and custom solutions to enhance user awareness and threat management. Their offerings support compliance reporting, protection of sensitive data, security investigations, network activity monitoring, and management of access control permissions. The company primarily serves IT and security professionals and operates in the United States and Canada. Founded in 2002, PacketMotion is headquartered in San Jose, California.

Truviso

Venture Round in 2009
Truviso data analytics software is designed to give network-driven businesses immediate insight into their operations through continuous analysis of live production data. These customers have traditional data warehouse and business intelligence solutions that cannot deliver actionable information from their production systems quickly enough, or cannot scale efficiently with rapidly increasing volumes of data. The flexibility Truviso customers gain by being able to combine current and historical data in real time provides them with accurate visibility and actionable information for their marketing, sales and operations teams, as well as for their partners and customers.

Vindicia

Series D in 2009
Vindicia offers comprehensive subscription management solutions that help businesses acquire and retain more customers. Providing much more than just a billing and payments system, the company’s SaaS-based subscription management platform combines big data analysis, strategic consulting and proprietary retention technology. Vindicia provides its clients with more recurring revenue, more customer data, better insights, and greater value throughout the entire subscriber lifecycle.

Relievant

Series C in 2009
Relievant Medsystems, Inc. is a medical device company focused on addressing chronic axial low back pain through a minimally invasive procedure known as Intracept. This innovative treatment specifically targets the basivertebral nerve, utilizing radio-frequency energy delivered through a small access tube into the vertebral body to ablate the nerve. The procedure is performed under real-time fluoroscopic guidance, ensuring precision and safety. Founded in 2004 and headquartered in Minneapolis, Minnesota, with an additional office in Sunnyvale, California, Relievant aims to provide low-risk therapeutic solutions that significantly improve the quality of life for patients suffering from vertebrogenic low back pain.

SS8 Networks

Venture Round in 2009
SS8 Networks, Inc. specializes in network compliance solutions for communications providers globally. The company offers a range of products, including Xcipio, a mediation tool for lawful intercept that connects telecommunications networks with governmental and law enforcement agencies; BreachDetect, a data breach detection solution; and Intellego, an application for real-time monitoring of criminal internet communications. SS8 also provides the Xcipio Probe, which accesses communication content from complex network architectures, featuring high-performance keyword search and security capabilities. The company's technology enables clients to identify, track, and investigate suspects and devices of interest by analyzing extensive records from network packets. SS8 serves a diverse clientele, including law enforcement agencies, telecommunications providers, and national governments. Founded in 1999, the company is headquartered in Milpitas, California.

Apieron

Series D in 2009
Apieron is a developer of a non-invasive device designed to monitor asthmatic conditions by measuring exhaled nitric oxide (eNO). This technology aids in the management of asthma and is currently cleared by the FDA for use exclusively in physician's offices. By providing healthcare professionals with a tool to assess and manage asthma more effectively, Apieron aims to improve patient care and outcomes in individuals suffering from this respiratory condition.

Sadra Medical

Series C in 2009
Sadra Medical is dedicated to creating innovative, minimally invasive alternatives to traditional surgical valve replacement, specifically targeting the treatment of aortic valve disease. The company aims to address the significant clinical need for effective therapies, as aortic valve stenosis affects approximately 3 million individuals in the United States, yet only a small percentage receive treatment through conventional open-heart surgery. By developing new devices that facilitate these advanced procedures, Sadra Medical seeks to enhance patient care and make valve replacement accessible to a broader range of patients. The company's goal is to reduce the risks and complications associated with open surgical procedures, providing a viable therapeutic option for those who currently lack effective treatment.

Mixercast

Series C in 2009
Mixercast allowed users to create embeddable slide show widgets. Users could mix together both personal and licensed content into their slide show.

Vidder

Series A in 2009
Vidder is a cybersecurity company based in Campbell, California, specializing in access control solutions that enhance network security. Established in 2009, Vidder's technology is centered around the Software-Defined Perimeter (SDP) standard, which aims to mitigate network-based attacks by rendering servers invisible to unauthorized users. The company's offerings include managed services that safeguard valuable networked assets while ensuring pre-authenticated, context-aware access to enterprise applications. By focusing on blocking connectivity from unknown devices, Vidder provides organizations with a robust defense against cyber threats, thereby reducing security risks associated with their digital infrastructure.

NetSeer

Venture Round in 2009
NetSeer, Inc. specializes in concept-based advertising solutions aimed at enhancing ad targeting for advertisers and publishers. The company has developed an intent engine called ConceptGraph, which decodes user intent to ensure ad placements are relevant and brand-safe. NetSeer offers a suite of products, including NetSeer BRAND, which curates brand-safe content for custom programmatic channels, and NetSeer RESPONSE, providing audience-targeting insights and optimization for improved campaign performance. Additionally, NetSeer ConceptLinks and InImageLinks serve as monetization tools that enhance user engagement by delivering relevant content and links within web pages and editorial images. Founded in 2006 and based in Mountain View, California, NetSeer operates as a subsidiary of Inuvo, Inc. and maintains a strategic partnership with LiveRamp.

Sentilla

Series B in 2009
Sentilla, based in Redwood City, California, specializes in data center management and IT intelligence infrastructure. The company provides a software solution that enhances visibility across physical, virtual, and cloud environments, enabling enterprises to optimize their IT resource utilization and align it with business needs. By offering services such as performance analysis, capacity management, and cloud migration, Sentilla aids clients in minimizing risks and improving infrastructure performance continually. Its software is utilized by global enterprises, including cloud service providers and telecommunications companies, to achieve significant efficiency gains, with clients reportedly realizing $1.40 for every dollar invested in IT. The company’s focus on reducing capital and operational expenditures allows businesses to deploy resources more quickly and enter new markets with agility.

Hotspur Technologies

Series A in 2008
Hotspur Technologies is a prominent developer of catheter-based technologies designed to restore blood flow in patients with obstructed vessels. The company specializes in creating innovative products that utilize unique technology to open blood vessels more effectively and with minimal invasiveness. Through its advancements, Hotspur Technologies aims to improve patient outcomes in the treatment of vascular obstructions.

Buysight

Series A in 2008
Buysight, formerly known as Permuto, aims to enhance the reach, performance, and measurability of display advertising, similar to search engine marketing. The company offers effective solutions tailored for both brand and performance advertisers, leveraging its proprietary online display advertising network, ShopperConnect™, which targets the expansive online e-commerce shopping market. Founded by industry veterans with experience from major tech companies, Buysight is positioned to innovate within the digital advertising landscape, providing valuable tools for advertisers seeking to optimize their campaigns.

BAROnova

Series B in 2008
BAROnova, Inc. is a clinical-stage medical-device company founded in 2006 and based in Goleta, California. The company specializes in developing non-surgical and non-pharmacologic devices aimed at inducing weight loss. Its primary product, the TransPyloric Shuttle, is designed to be inserted into the stomach through the mouth via a simple endoscopic procedure. This device helps patients feel full more quickly, prolongs the sensation of fullness, and delays gastric emptying, thereby supporting weight loss efforts.

Valeritas

Series A in 2008
On June 30, 2020, Valeritas Holdings, Inc. went out of business as per its Chapter 11 liquidation filing under bankruptcy. Valeritas Holdings, Inc., a commercial-stage medical technology company, focuses on the development and commercialization of technologies to treat patients with Type 2 diabetes in the United States. The company offers V-Go, a wearable insulin delivery device for basal-bolus therapy. It also develops V-Go Prefill that is in the design-development stage for eliminating the device-filling process and the need for EZ fill refrigeration for patients with Type 2 diabetes; and V-Go SIM for real-time tracking information of basal and bolus dosing utilization. The company sells V-Go to third-party wholesalers and medical supply distributors. Valeritas Holdings, Inc. was founded in 2006 and is headquartered in Bridgewater, New Jersey.
Brilliant Telecommunications, Inc. designs, develops, and distributes network timing, management, and synchronization solutions. Its products include Zurich Z-1000, a zero footprint, outdoor, and pole-mounted Network Time Protocol server that embodies its own timing management interface to provide tools for diagnosis, monitoring, and alarms; Cern C-2000, which is a Primary Reference Source and Clock that provides time stamping accuracy and configurability; and BT-750, a network timing client that delivers multiple synchronous outputs in a flexible platform. The company serves financial markets, legal institutions, telecommunication companies, and manufacturing organizations. Brilliant Telecommunications, Inc. was founded in 2004 and is based in Campbell, California.

XORP Inc.

Series A in 2008
XORP Inc. is the company behind XORP, an open source internet protocol routing software.

Arcot

Series B in 2008
Arcot Systems, Inc. specializes in authentication and digital signing solutions designed to protect and verify the digital identities of cardholders and merchants. Founded in 1997 and headquartered in Sunnyvale, California, with a technology center in Bangalore, India, the company offers a range of products, including TransFort for Issuers and Merchants, which facilitate secure authentication processes; RiskFort, which addresses real-time fraud prevention; and SignFort, which streamlines document signing and approval. Additional solutions include WebFort and ArcotID for software-based authentication, as well as A-OK On-Demand for enhanced security in authentication. Arcot Systems caters to various sectors, including financial institutions, pharmaceutical companies, and e-commerce platforms, helping them mitigate online fraud and identity theft while ensuring compliance with regulatory standards.

NovaSys

Venture Round in 2008
At NovaSys Health they value your participation as a contracted provider. Roughly 11,000 providers in this region and over 4,300 providers in Arkansas have contracted with NovaSys Health making it one of the largest health plans in Arkansas. They take pride in the relationships that they have cultivated with providers.

NOVASYS MEDICAL

Series D in 2008
$25 million in Series C preferred stock financing. The financing will be used to ramp up operations and prepare for sales and marketing in anticipation of the company commercializing its first product, the Novasys Micro-remodeling™ System. The system, which is designed to treat female stress urinary incontinence (SUI), has received the CE Mark for use in the European Union and is pending FDA marketing clearance for sale in the United States. Novasys Medical Inc is testing a new, non-incisional, transurethral treatment which requires no visualization of the treatment site (neither cystoscopy nor fluoroscopy), being guided by familiar balloon palpation (similar to a Foley catheter). In addition, the Novasys Micro-remodeling™ System incorporates numerous, automatic safety features making the treatment process very easy to learn and use. The treatment does not require general anesthesia and is performed in the outpatient or office setting. Not only is the treatment rapid (less than 10 minutes), but patients immediately return to virtually all activities. As there are no incisions, no wound care or dressing changes are required.

obopay

Series D in 2008
Obopay lets consumers and businesses purchase, pay, and transfer money through any mobile phone using Obopay’s mobile application, text message, mobile Web, or Obopay.com. Obopay works on any mobile phone and any carrier in the U.S. Obopay’s prepaid MasterCard works with any merchant that accepts MasterCard debit cards. Obopay has partnerships with Citi, Fidelity Information Services, MasterCard MoneySend, Bancorp, Verizon Wireless, AT&T and RIM. Obopay has a wholly owned subsidiary in India whose service launched in March, 2008. Obopay India has announced partnerships with YES Bank, Aircel, BPL and Tata Indicom.

CardioMind

Venture Round in 2008
CardioMind, Inc. Inc manufactures therapeutic devices for cardiovascular diseases. The company also offers stent delivery systems, which are designed for use in lesion applications, as well as for the treatment of coronary and peripheral artery diseases. In addition, it provides invasive endovascular medical devices for treating neurological and cardiovascular diseases. The company was founded in 2003 and is based in Sunnyvale, California.

Adaptive Insights

Series D in 2008
Adaptive Insights, Inc. specializes in integrated cloud-based corporate performance management (CPM) and business intelligence (BI) solutions. The company offers a suite of products designed to enhance business planning and financial consolidation, including Adaptive Suite, Adaptive Planning, and Adaptive Consolidation. These tools facilitate intuitive planning, forecasting, reporting, and dashboards that enable organizations to streamline their financial processes. Additionally, Adaptive Insights provides solutions for workforce and expense management, capital management, and profitability analysis, among others. The company is recognized for its user-friendly interface and has received high customer satisfaction ratings in industry surveys. Serving a diverse range of sectors, including healthcare, retail, financial services, and manufacturing, Adaptive Insights empowers organizations to make informed decisions and improve their business agility. Founded in 2003 and headquartered in Palo Alto, California, the company operates as a subsidiary of Workday, Inc.

Aragon Surgical

Series B in 2008
Aragon Surgical, Inc. is a privately owned company established in 2005 that focuses on developing and commercializing innovative surgical products aimed at enhancing patient safety and reducing operative time. The company collaborates with various surgeons to identify opportunities for improving surgical performance. Its devices are specifically designed to assist gynecologic surgeons, general surgeons, and surgical specialists in both laparoscopic and open procedures. Through its commitment to surgical innovation, Aragon Surgical seeks to address critical needs within the surgical community.

Mixercast

Series B in 2008
Mixercast allowed users to create embeddable slide show widgets. Users could mix together both personal and licensed content into their slide show.

SquareOne

Series C in 2007
SquareOne is a content creation platform designed to support established personalities and content creators in the gaming industry. The company understands the unique needs of its partners and offers tailored assistance that emphasizes high-quality service over a broad reach. By providing professional support in areas such as revenue opportunities, brand growth, and technical guidance, SquareOne enables creators to thrive in a competitive landscape. The focus on individualized support helps creators to continue their growth and success in the gaming sector.

PacketMotion

Series C in 2007
PacketMotion, Inc. specializes in developing security solutions that help enterprises monitor user activity within their networks. The company's primary offering is the PacketSentry appliance, which allows organizations to track user behavior across server and application platforms. In addition to its core product, PacketMotion provides a range of services such as installation, training, and custom solutions to enhance user awareness and threat management. Their offerings support compliance reporting, protection of sensitive data, security investigations, network activity monitoring, and management of access control permissions. The company primarily serves IT and security professionals and operates in the United States and Canada. Founded in 2002, PacketMotion is headquartered in San Jose, California.

CardioMind

Series C in 2007
CardioMind, Inc. Inc manufactures therapeutic devices for cardiovascular diseases. The company also offers stent delivery systems, which are designed for use in lesion applications, as well as for the treatment of coronary and peripheral artery diseases. In addition, it provides invasive endovascular medical devices for treating neurological and cardiovascular diseases. The company was founded in 2003 and is based in Sunnyvale, California.

Arcot

Venture Round in 2007
Arcot Systems, Inc. specializes in authentication and digital signing solutions designed to protect and verify the digital identities of cardholders and merchants. Founded in 1997 and headquartered in Sunnyvale, California, with a technology center in Bangalore, India, the company offers a range of products, including TransFort for Issuers and Merchants, which facilitate secure authentication processes; RiskFort, which addresses real-time fraud prevention; and SignFort, which streamlines document signing and approval. Additional solutions include WebFort and ArcotID for software-based authentication, as well as A-OK On-Demand for enhanced security in authentication. Arcot Systems caters to various sectors, including financial institutions, pharmaceutical companies, and e-commerce platforms, helping them mitigate online fraud and identity theft while ensuring compliance with regulatory standards.

Pegasus Biologics

Series C in 2007
Pegasus Biologics, Inc. engages in manufacturing, developing, and marketing bioimplants for soft tissue repair and wound care for diabetic ulcers. Its products include OrthADAPT Bioimplant, which is an organized tissue scaffold that used for the repair and reinforcement of soft tissues, such as tendons and ligaments; and Unite Biomatrix, which is an enzyme resistant collagen scaffold that allows for suture retention and intrinsic strength. The company serves orthopedics, sports medicine, neurosurgical, and spine applications. Pegasus Biologics, Inc. was founded in 2003 and is based in Irvine, California. As of July 17, 2009, Pegasus Biologics, Inc. operates as a subsidiary of Synovis Life Technologies Inc.

SquareOne

Series C in 2007
SquareOne is a content creation platform designed to support established personalities and content creators in the gaming industry. The company understands the unique needs of its partners and offers tailored assistance that emphasizes high-quality service over a broad reach. By providing professional support in areas such as revenue opportunities, brand growth, and technical guidance, SquareOne enables creators to thrive in a competitive landscape. The focus on individualized support helps creators to continue their growth and success in the gaming sector.

Adaptive Insights

Series C in 2007
Adaptive Insights, Inc. specializes in integrated cloud-based corporate performance management (CPM) and business intelligence (BI) solutions. The company offers a suite of products designed to enhance business planning and financial consolidation, including Adaptive Suite, Adaptive Planning, and Adaptive Consolidation. These tools facilitate intuitive planning, forecasting, reporting, and dashboards that enable organizations to streamline their financial processes. Additionally, Adaptive Insights provides solutions for workforce and expense management, capital management, and profitability analysis, among others. The company is recognized for its user-friendly interface and has received high customer satisfaction ratings in industry surveys. Serving a diverse range of sectors, including healthcare, retail, financial services, and manufacturing, Adaptive Insights empowers organizations to make informed decisions and improve their business agility. Founded in 2003 and headquartered in Palo Alto, California, the company operates as a subsidiary of Workday, Inc.
Brilliant Telecommunications, Inc. designs, develops, and distributes network timing, management, and synchronization solutions. Its products include Zurich Z-1000, a zero footprint, outdoor, and pole-mounted Network Time Protocol server that embodies its own timing management interface to provide tools for diagnosis, monitoring, and alarms; Cern C-2000, which is a Primary Reference Source and Clock that provides time stamping accuracy and configurability; and BT-750, a network timing client that delivers multiple synchronous outputs in a flexible platform. The company serves financial markets, legal institutions, telecommunication companies, and manufacturing organizations. Brilliant Telecommunications, Inc. was founded in 2004 and is based in Campbell, California.

Sadra Medical

Series B in 2006
Sadra Medical is dedicated to creating innovative, minimally invasive alternatives to traditional surgical valve replacement, specifically targeting the treatment of aortic valve disease. The company aims to address the significant clinical need for effective therapies, as aortic valve stenosis affects approximately 3 million individuals in the United States, yet only a small percentage receive treatment through conventional open-heart surgery. By developing new devices that facilitate these advanced procedures, Sadra Medical seeks to enhance patient care and make valve replacement accessible to a broader range of patients. The company's goal is to reduce the risks and complications associated with open surgical procedures, providing a viable therapeutic option for those who currently lack effective treatment.

Sentilla

Series A in 2006
Sentilla, based in Redwood City, California, specializes in data center management and IT intelligence infrastructure. The company provides a software solution that enhances visibility across physical, virtual, and cloud environments, enabling enterprises to optimize their IT resource utilization and align it with business needs. By offering services such as performance analysis, capacity management, and cloud migration, Sentilla aids clients in minimizing risks and improving infrastructure performance continually. Its software is utilized by global enterprises, including cloud service providers and telecommunications companies, to achieve significant efficiency gains, with clients reportedly realizing $1.40 for every dollar invested in IT. The company’s focus on reducing capital and operational expenditures allows businesses to deploy resources more quickly and enter new markets with agility.

Relievant

Series B in 2006
Relievant Medsystems, Inc. is a medical device company focused on addressing chronic axial low back pain through a minimally invasive procedure known as Intracept. This innovative treatment specifically targets the basivertebral nerve, utilizing radio-frequency energy delivered through a small access tube into the vertebral body to ablate the nerve. The procedure is performed under real-time fluoroscopic guidance, ensuring precision and safety. Founded in 2004 and headquartered in Minneapolis, Minnesota, with an additional office in Sunnyvale, California, Relievant aims to provide low-risk therapeutic solutions that significantly improve the quality of life for patients suffering from vertebrogenic low back pain.

AirPlay Network

Series B in 2006
AirPlay creates and produces games that allow consumers to use their cell phones to play along with their favorite television programs. Merging 110 million US television households with 200 million mobile handsets, AirPlay offers consumers a fun and unique way to interact with live television while competing against their friends, family or a national television audience. For its wireless and television industry partners, AirPlay offers a proprietary platform and service infrastructure which enables incremental revenue streams without partner capital investment

PacketMotion

Series B in 2006
PacketMotion, Inc. specializes in developing security solutions that help enterprises monitor user activity within their networks. The company's primary offering is the PacketSentry appliance, which allows organizations to track user behavior across server and application platforms. In addition to its core product, PacketMotion provides a range of services such as installation, training, and custom solutions to enhance user awareness and threat management. Their offerings support compliance reporting, protection of sensitive data, security investigations, network activity monitoring, and management of access control permissions. The company primarily serves IT and security professionals and operates in the United States and Canada. Founded in 2002, PacketMotion is headquartered in San Jose, California.

obopay

Series B in 2006
Obopay lets consumers and businesses purchase, pay, and transfer money through any mobile phone using Obopay’s mobile application, text message, mobile Web, or Obopay.com. Obopay works on any mobile phone and any carrier in the U.S. Obopay’s prepaid MasterCard works with any merchant that accepts MasterCard debit cards. Obopay has partnerships with Citi, Fidelity Information Services, MasterCard MoneySend, Bancorp, Verizon Wireless, AT&T and RIM. Obopay has a wholly owned subsidiary in India whose service launched in March, 2008. Obopay India has announced partnerships with YES Bank, Aircel, BPL and Tata Indicom.

Neuronetics

Series C in 2006
Neuronetics is a medical technology company based in Malvern, Pennsylvania, established in 2003. It specializes in developing non-invasive therapies for psychiatric and neurological disorders, particularly Major Depressive Disorder (MDD). The company's flagship product, the NeuroStar Advanced Therapy System, utilizes transcranial magnetic stimulation (TMS) to deliver MRI-strength magnetic pulses that induce electrical currents in targeted areas of the brain associated with mood regulation. This innovative treatment is the first of its kind to receive FDA clearance for patients who have not found relief from traditional antidepressant therapies. Neuronetics aims to improve the quality of life for individuals suffering from mental health conditions through its advanced, non-systemic treatment options.

SS8 Networks

Series A in 2006
SS8 Networks, Inc. specializes in network compliance solutions for communications providers globally. The company offers a range of products, including Xcipio, a mediation tool for lawful intercept that connects telecommunications networks with governmental and law enforcement agencies; BreachDetect, a data breach detection solution; and Intellego, an application for real-time monitoring of criminal internet communications. SS8 also provides the Xcipio Probe, which accesses communication content from complex network architectures, featuring high-performance keyword search and security capabilities. The company's technology enables clients to identify, track, and investigate suspects and devices of interest by analyzing extensive records from network packets. SS8 serves a diverse clientele, including law enforcement agencies, telecommunications providers, and national governments. Founded in 1999, the company is headquartered in Milpitas, California.

Uptake Medical

Series A in 2006
Uptake Medical specializes in developing innovative medical technologies aimed at treating lung diseases. The company's flagship product, InterVapor™, is an endoscopic lung volume reduction therapy designed specifically for individuals with severe emphysema. This unique approach leverages the body’s natural healing processes and does not introduce any foreign materials into the lungs. Clinical studies have shown that InterVapor™ can lead to significant improvements in patients' breathing function, exercise capacity, and overall quality of life.

Nextance

Series E in 2006
Nextance, Inc. is an enterprise software provider that focuses on helping companies manage and optimize their B2B relationships. Founded in 2000 and headquartered in Austin, Texas, the company specializes in proposal and contract management software, which enhances the standardization, visibility, and control of critical relationship-defining documents. Its offerings include tools for sales and sales operations, procurement agreements, and contract management, along with features such as automatic notifications, contract status tracking, and reviews. Additionally, Nextance provides a range of services including business impact assessments, process consulting, data migration, implementation, training, and ongoing technical support. As of 2007, Nextance operates as a subsidiary of Versata Inc.

obopay

Series A in 2006
Obopay lets consumers and businesses purchase, pay, and transfer money through any mobile phone using Obopay’s mobile application, text message, mobile Web, or Obopay.com. Obopay works on any mobile phone and any carrier in the U.S. Obopay’s prepaid MasterCard works with any merchant that accepts MasterCard debit cards. Obopay has partnerships with Citi, Fidelity Information Services, MasterCard MoneySend, Bancorp, Verizon Wireless, AT&T and RIM. Obopay has a wholly owned subsidiary in India whose service launched in March, 2008. Obopay India has announced partnerships with YES Bank, Aircel, BPL and Tata Indicom.

Invarium

Series B in 2006
Invarium, Inc. specializes in providing advanced patterning synthesis solutions for the semiconductor industry. Headquartered in San Jose, California, the company offers DimensionPPC, a technology that enhances pattern accuracy on silicon, specifically for integrated circuit (IC) designs, while also facilitating quicker time-to-volume production. Invarium's services are particularly beneficial for sub-90-nanometer IC designers and manufacturers, addressing layout printability challenges in complex chip designs. Since its incorporation in 2003, Invarium has established itself as a key player in the semiconductor sector, operating as a subsidiary of Cadence Design Systems as of 2007.

VM Discovery

Series B in 2006
VM Discovery, Inc. is a drug design and discovery company based in Fremont, California, established in 2001. The company specializes in providing drug design and optimization services to help clients identify drug candidates that are optimized across multiple properties. VM Discovery employs advanced technology for comprehensive parallel modeling, optimization, and virtual screening, allowing for the selection of small molecule drug candidates with balanced potency. Its offerings include both collaborative projects with pharmaceutical and biotech companies in the United States and Asia, as well as the provision of internally optimized drug candidates. This approach enables clients to expedite the drug development process while minimizing resource expenditure.

BAROnova

Series A in 2006
BAROnova, Inc. is a clinical-stage medical-device company founded in 2006 and based in Goleta, California. The company specializes in developing non-surgical and non-pharmacologic devices aimed at inducing weight loss. Its primary product, the TransPyloric Shuttle, is designed to be inserted into the stomach through the mouth via a simple endoscopic procedure. This device helps patients feel full more quickly, prolongs the sensation of fullness, and delays gastric emptying, thereby supporting weight loss efforts.

Securent

Series A in 2006
Securent, Inc. offers application entitlement management solution (EMS) that enables organizations to secure sensitive applications and data. Its EMS enables organizations to centrally configure, control, view, and audit fine-grained access policies for enterprise content across various repositories and access channels. The company sells its products to enterprises or government agencies that need to control access to sensitive applications or confidential information, including customer data, employee records, product plans, or financial statements. Securent was founded in 2004 and is based in Mountain View, California. It has additional offices in the United States; and Hyderabad, India. As of November 19, 2007, Securent, Inc. is a subsidiary of Cisco Systems, Inc. (NasdaqNM:CSCO).

Oculir

Series A in 2005
Oculir develops non-invasive glucose meter that measures glucose from the conjunctiva of the eye.

Blue Vector Systems

Series B in 2005
Blue Vector Systems provides asset tracking and supply chain visibility solutions to pharmaceutical, retail, distribution, and manufacturing industries. The company was founded in 2002 and is headquartered in Mountain View, California.
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