Investors in Pennsylvania

Showing 1-50 out of 1061 matches

Ben Franklin Technology Partners of Southeastern Pennsylvania

Ben Franklin Technology Partners of Southeastern Pennsylvania is a nonprofit organization founded in 1982 that supports the technology ecosystem in Southeastern Pennsylvania by providing capital, guidance, and connections to early-stage technology companies. It acts as a seed-stage capital provider for the region's technology sectors, facilitates university-industry partnerships to accelerate commercialization, and undertakes initiatives to strengthen the entrepreneurial community across Philadelphia and surrounding counties, with a focus on creating jobs and fostering regional innovation.
Made 141 investments in Pennsylvania

Innovation Works

Innovation Works is a Pittsburgh-based venture capital firm and regional technology-support organization that funds seed-stage technology companies in Southwestern Pennsylvania. It provides capital, mentorship, and programmatic resources to startups in robotics, hardware, software, and life sciences, and operates accelerators and programs such as AlphaLab, the Robotics Factory, the Seed Fund, and Manufacturing Assistance to advance prototypes to production. As the Ben Franklin Technology Partner for Southwestern Pennsylvania, supported by the Pennsylvania Department of Community and Economic Development, it connects founders with capital, expertise, and a broad regional network to help companies grow faster. Throughout its history, Innovation Works has nurtured hundreds of startups and aided portfolio firms in raising substantial follow-on funding and achieving exits, underscoring its role as a leading early-stage investor and ecosystem builder in the region.
Made 372 investments in Pennsylvania

Aspire Ventures

Aspire Ventures is a venture capital firm headquartered in Lancaster, Pennsylvania, founded in 2014. The firm focuses on investments in healthcare and digital health, with emphasis on technologies such as artificial intelligence, Internet of Things, information technology, and mobile sectors. Aspire Ventures leverages capital, intellectual property, and domain expertise in IoT to support startups in transforming healthcare and accelerating product development. It operates a Smart Health Innovation Lab that provides mentorship, testing environments, and access to enterprise opportunities to early-stage ventures, helping bridge concept to market. The firm combines strategic resources with a rigorous approach to accelerate ventures from concept to market, including precision medicine initiatives that harness AI and IoT to advance healthcare solutions.
Made 3 investments in Pennsylvania

Robin Hood Ventures

Robin Hood Ventures is an angel investment group based in Philadelphia, Pennsylvania, active since 1999 and focused on early-stage, high-growth startups in the mid-Atlantic region. It provides capital, mentoring, expertise and connections to help entrepreneurs build scalable companies, typically investing between 250,000 and 1,000,000 per deal and often syndicating with other angels and venture capitalists. The firm targets sectors including information technology services and software, life sciences, hard technology, consumer, and financial technology, and it invests as a single entity in familiar ventures to expedite transactions. It emphasizes collaboration within the startup ecosystem, offering guidance and access to a network of investors, institutions and partners, and actively seeks new members, entrepreneurs and opportunities to foster growth.
Made 46 investments in Pennsylvania

Alumni Ventures

Alumni Ventures is a venture capital firm based in Manchester, New Hampshire, with offices in New York, Boston, Menlo Park, Chicago, London, and Tokyo. It enables accredited investors, especially alumni networks, to access diversified venture opportunities by co-investing alongside leading venture capital firms. Through funds, syndicates, and investing clubs, it sources opportunities across stages and geographies, conducts rigorous due diligence, and aims for transparent, founder-friendly support. The firm backs a diversified portfolio of startups, including more than 1,600 companies, and has attracted substantial committed capital and a large community of individual investors, underscoring its mission to democratize access to venture capital while partnering with established VC firms.
Made 36 investments in Pennsylvania

Dreamit Ventures

Dreamit Ventures is a venture firm and accelerator that supports early to growth-stage technology startups, with a focus on cybersecurity, health tech, software, and other high-growth sectors. The company provides seed funding along with structured programs, including customer sprints, partner introductions to potential customers and investors, and mentorship to accelerate product-market fit and fundraising. Since its founding in 2008, Dreamit has backed hundreds of startups and built a broad network of enterprise partners to help portfolio companies validate pilots, scale revenue, and pursue strategic partnerships.
Made 56 investments in Pennsylvania

Pittsburgh Life Sciences Greenhouse

Pittsburgh Life Sciences Greenhouse is a Pittsburgh-based investment and business-support organization founded in 2002 as a public-private effort to grow the western Pennsylvania life sciences industry. It provides capital investments and customized company formation and growth services to early-stage bioscience ventures, with focus areas including biotechnology tools, diagnostics, medical devices, therapeutics, and healthcare information technology. The organization targets companies in Western Pennsylvania, assisting them from incubation through growth phases and helping them develop, commercialize, and scale innovations in the life sciences sector.
Made 35 investments in Pennsylvania

AlphaLab

AlphaLab is a Pittsburgh-based startup accelerator and incubator founded in 2008 that supports early-stage technology companies across software, hardware, life sciences, and robotics. The organization provides seed capital, mentorship, sector-specific workshops, workspace, lab access, and resources for investor preparation, helping founders refine value propositions and pursue commercialization. It operates a hardware-focused accelerator, AlphaLab Gear, offering a 30-week program with funding, office space, education sessions, customer connections, and mentorship from industry experts for physical product ventures. AlphaLab emphasizes access to customers, capital, and a supportive community, and maintains ties with Pittsburgh's universities and strong local talent. The program aims to accelerate product development, market entry, and fundraising readiness for its participants.
Made 50 investments in Pennsylvania

Mountain State Capital

Mountain State Capital is a venture capital firm based in Morgantown, West Virginia, with an additional office in Pittsburgh, Pennsylvania. It focuses on seed and early-stage technology companies in the Greater Appalachian region, covering West Virginia, Pennsylvania, Ohio, Maryland, Virginia, Kentucky, Tennessee, and North Carolina. The firm typically invests $250,000 to $500,000 in initial funding within a larger Seed round to provide 12 to 18 months of runway, targeting companies that have achieved product-market fit and are positioned to scale. It backs ventures across software, hardware, services, and life sciences, and prioritizes supporting companies within a multi-hour drive of its offices. Mountain State Capital has a track record of successful exits and has advised over 100 private companies, reflecting an active role in the regional innovation ecosystem. Notable investments include Peptilogics, Aspinity, InspectionGo, and Gridwise.
Made 18 investments in Pennsylvania

UPMC

UPMC is a leading nonprofit health system headquartered in Pittsburgh, operating hospitals, clinics, and care centers across Western and Central Pennsylvania, Maryland, New York, and internationally. It provides primary and specialty services including cardiology, oncology, orthopedics, and rehabilitation, supported by research and a commitment to accessibility and innovation. The organization emphasizes telemedicine and patient resources to improve care delivery and outcomes, and pursues Life Changing Medicine through technology and translational science. UPMC also encompasses UPMC Health Plan, a regional insurer offering commercial and government programs with a broad provider network, and UPMC Enterprises, the venture and innovation arm that funds and partners with health care startups to bring new diagnostics, therapies, and digital solutions to patients.
Made 12 investments in Pennsylvania

Newlin Investment Company

Newlin Investment Company is a private equity and venture capital firm based in Sewickley, Pennsylvania. It provides long-term capital to early-stage and growth companies in technology, industrial, and life sciences sectors, as well as retail markets. The firm often acts as an active partner, offering advisory support and board involvement to portfolio companies, with a focus on university spin-outs. It pursues a long-term investment approach and aims to create value through strategic planning, operational improvements, and collaboration with management teams.
Made 6 investments in Pennsylvania

Gabriel Investments

Gabriel Investments is a Philadelphia-based venture capital firm that provides early-stage capital and strategic support to high-potential startups. The firm backs companies in pre-revenue or proof-of-concept stages with the potential for rapid growth, aiming for long-term ownership and active involvement beyond capital. Its approach leverages the members’ experience, networks, and expertise to help shape business plans, recruit management, develop go-to-market strategies, and form strategic partnerships. Founded in 2010, Gabriel Investments focuses on information technology, B2C and B2B applications, advertising technology, big data, e-commerce, financial technology, food technology, mobile, marketing technology, and software-as-a-service sectors, seeking opportunities across technology-enabled sectors in the Philadelphia region and beyond.
Made 9 investments in Pennsylvania

Gaingels

Gaingels is a venture investment syndicate focused on supporting LGBTQ founders and inclusive leadership by investing across stages and partnering with other venture firms to back diverse, high-potential companies. It maintains a global portfolio of 130+ companies and has deployed tens of millions in capital to date. The organization actively helps portfolio companies identify and recruit diverse talent for C-suite and board roles and cultivates a worldwide network of investors, operators, and entrepreneurs who share a commitment to positive social change through business.
Made 9 investments in Pennsylvania

Adams Capital Management

Adams Capital Management is a Pittsburgh-area venture capital firm founded in 1994 that concentrates on early-stage applied technology investments and often acts as a lead Series A investor. It focuses on information technology, networking infrastructure, semiconductor, software as a service, and related technologies, including AI, big data, cybersecurity and infrastructure sectors, with a national US footprint. The firm manages hundreds of millions of dollars in capital and supports portfolio companies with its operational expertise to help them scale into market-leading businesses.
Made 16 investments in Pennsylvania

Pittsburgh Equity Partners

Pittsburgh Equity Partners is a venture capital investment firm based in Bridgeville, Pennsylvania, focused on growing early‑stage technology, information technology, and life sciences companies in Western Pennsylvania. Founded in 2009, it supports a portfolio that includes ShowClix, Voci, Wombat, and Industry Weapon across sectors such as ticketing, AI, cybersecurity, and communications. The firm emphasizes partnerships with regional sponsors and institutions, including InnovationWorks, Carnegie Mellon University, and the University of Pittsburgh, to identify opportunities and guide portfolio companies. Through active involvement and strategic mentorship, Pittsburgh Equity Partners aims to accelerate growth, contribute to the regional economy, and help its companies reach scale. The portfolio reportedly generates about $3 billion in annual revenue, employs over 600 people, and provides roughly $60 million in annual payroll.
Made 8 investments in Pennsylvania

Red & Blue Ventures

Red & Blue Ventures is a Philadelphia-based seed and early-stage venture capital firm focused on technology-enabled services and information technology. It targets opportunities originating from the University of Pennsylvania ecosystem, including Penn-affiliated founders, faculty, students, or IP, and operates independently of the university while leveraging its network to add value to portfolio companies. The firm emphasizes early-stage investments in software, hardware, ecommerce, and related technology sectors, often backing ventures that leverage Penn connections and expertise.
Made 9 investments in Pennsylvania

Safeguard Scientifics

Safeguard Scientifics is a growth capital and strategic support firm based in Radnor, Pennsylvania, with a history dating to 1953. It provides capital and operational guidance to technology-driven companies in healthcare, financial services, and digital media, leveraging founder and operator experience to help early- and growth-stage ventures accelerate growth and create long-term value. The firm typically makes growth equity and early-stage investments, often as the largest shareholder, and seeks board participation to influence governance and strategic direction. It emphasizes investments in companies with proprietary technology and intellectual property, spanning the United States with a focus on the Mid-Atlantic region and neighboring markets.
Made 19 investments in Pennsylvania

Delaware Crossing Investor Group

Delaware Crossing Investor Group is a private equity and venture capital network of seasoned executives and entrepreneurs that provides capital and governance guidance to early-stage and growth-oriented companies. Operating as a membership-based group, it sources opportunities, manages the investment process, and often serves on the boards of portfolio companies. Based in Warrington, Pennsylvania, and founded in 2005, the group targets companies across software, internet, information technology, life sciences, advanced materials, consumer products, medical devices, and diagnostics, with typical funding in the range of 250,000 to 1,000,000 and per-round investments around 250,000. The organization offers screening, due diligence, deal management, post-investment follow-up, and ongoing support through its network to help portfolio companies grow and navigate strategic challenges in the Philadelphia region and adjacent markets.
Made 5 investments in Pennsylvania

SOSV

SOSV is a global venture capital firm that provides early-stage and seed investments alongside structured accelerator programs and deeply resourced facilities to accelerate product development. Focused on deep tech, human and planetary health, and cross-border software, SOSV backs startups from pre-seed onward and runs programs that accelerate technical development, regulatory strategy, and fundraising. The firm maintains labs and engineering spaces with specialist staff in multiple regions, including the United States and Asia, to support portfolio companies in biosafety, chemistry, mechatronics, analytics, and electrical engineering. Programs such as HAX and other live events offer founders access to prototyping, testing, and investor networks. Annually, SOSV makes around sixty pre-seed investments (up to roughly $550k each) and participates in numerous follow-on rounds, leveraging a global portfolio and extensive co-investor network to help deeply technical startups scale and reach markets.
Made 17 investments in Pennsylvania

RA Capital Management

RA Capital Management is a Boston-based investment firm focused on healthcare, life sciences, and planetary health, investing in public and private companies across stages from seed to late-stage financings. The firm emphasizes evidence-based, science-led investing guided by internal research capabilities, including TechAtlas. It operates Raven, a biomedical innovation incubator that supports entrepreneurs and developers, and pursues value creation through collaborative partnerships, often co-investing and taking board positions. With a multidisciplinary, data-driven approach, RA Capital seeks to back management teams from inception through commercialization and beyond, aiming to improve patient outcomes and advance medical innovation.
Made 9 investments in Pennsylvania

Draper Triangle Ventures

An early-stage venture capital firm based in Pittsburgh, Draper Triangle Ventures backs technology startups in the United States, with a Midwest focus. The firm invests in software, information technology, hardware and life sciences technology, including robotics, medical devices, SaaS, big data, and connected devices. It operates with a regional footprint across Pennsylvania, Ohio, Michigan and neighboring states, and maintains additional offices in Cleveland, Detroit, Columbus and Ann Arbor. Draper Triangle collaborates through the Draper Venture Network to source opportunities and co-investments. It typically participates in seed to early-stage rounds, seeks a lead position or significant board involvement, and targets first-round investments in the range of hundreds of thousands to a few million dollars, aiming for portfolio companies to achieve substantial growth within three to five years.
Made 27 investments in Pennsylvania

Ben Franklin Technology Partners of Central and Northern Pennsylvania

Ben Franklin Technology Partners of Central and Northern Pennsylvania is a state-supported technology economic development organization based in State College, Pennsylvania. Founded in 1983, it provides early-stage funding and business support services to technology-based startups and small manufacturing companies across a 32-county region. As part of a statewide network of Ben Franklin centers, it serves as an accelerator by offering financing pathways and mentorship to help firms develop innovative products or processes and position themselves for follow-on investments from banks, angels, or venture capital. The organization aims to foster collaboration among business, industry, and higher education to spur economic growth, create high-paying jobs, and build regional expertise in emerging technologies.
Made 17 investments in Pennsylvania

Devon Park Bioventures

Devon Park Bioventures is a venture capital firm based in Wayne, Pennsylvania in the Philadelphia metropolitan area. Founded in 2006, it focuses on investments in life sciences companies across the United States, particularly in therapeutics, medical devices, diagnostics, and drug discovery technologies.
Made 1 investment in Pennsylvania

White Rose Ventures

White Rose Ventures is a venture capital firm based in York, Pennsylvania, focused on early-stage technology companies in Central Pennsylvania. Founded in 2020, the firm seeks to support ambitious regional entrepreneurs by providing initial funding and strategic guidance to accelerate growth and long-term sustainability. It concentrates on technology ventures and prioritizes opportunities within the Central Pennsylvania ecosystem. The firm operates alongside the Braided River Collective, a sister initiative that supports innovators, creatives, and entrepreneurs, reflecting a broader effort to nurture local innovation. White Rose Ventures maintains an active stance toward new opportunities from local founders and operators seeking to build sustainable, scalable businesses in the region.

Magarac Venture Partners

Magarac Venture Partners is a Pittsburgh-based early-stage venture capital firm founded in 2021 that invests in Midwest technology companies, typically at Seed and Series A rounds. It backs market-defining startups by providing capital and resources, with a people-first approach and emphasis on supporting founders. The firm focuses on the Midwest technology ecosystem, with activity in Pittsburgh, Columbus, and Detroit, and seeks to leverage regional strengths. The team includes veterans from Draper Triangle Ventures, guiding portfolio companies across sectors such as cybersecurity, retail innovation, real estate tech, virtual reality, and athletic technology, among others. Magarac emphasizes diversity and inclusion, with policies guiding representation within portfolios and hiring interviews at senior levels. The firm aims to empower bold founders to shape the future.
Made 1 investment in Pennsylvania

HealthVerity

HealthVerity is a Philadelphia-based healthcare data technology company founded in 2014 that builds cloud-based tools to discover, de-identify, match, and integrate patient data from diverse sources, enabling pharmaceutical manufacturers, hospitals, and payers to assemble an optimal patient data set while supporting privacy-preserving data exchange and governance. Its platform unifies clinical and commercial data through the HealthVerity Marketplace and related solutions, offers AI-native real-world evidence generation through HealthVerity eXOs, and provides identity management and taxonomy pathways to enhance data quality and interoperability. The company emphasizes data quality and secure analytics to illuminate patient journeys, support research and commercialization, and accelerate insights across life sciences, insurance, government, and channel partners, including strategic collaborations with Parexel and Medidata.
Made 1 investment in Pennsylvania

Next Act Fund

Next Act Fund is an angel investment group based in Pittsburgh, Pennsylvania, focused on funding women-owned or led early-stage companies in the Greater Pittsburgh region. Established to empower women in the angel investing community and to drive regional economic growth, the group supports its target companies through early investments and follow-on capital while providing educational programming for members and the public. The organization emphasizes creating opportunities and wealth for its investors and the broader community and positions itself as a catalyst for women’s entrepreneurship in Southwestern Pennsylvania. Reports indicate that the fund has deployed capital and, on its fifth anniversary, was not accepting new applications for funding, reflecting a matured stage of the program.

Broad Street Angels

Broad Street Angels is a Philadelphia-based angel investor network affiliated with the Union League of Philadelphia. Established in 2017, it operates as a member-led group that supports early-stage, high-growth startups in the Mid-Atlantic through capital and strategic guidance, leveraging its members' expertise to provide funding, mentorship, and connections to help portfolio companies scale. The network aims to strengthen the regional economy, retain and attract talent, and foster innovation and civic infrastructure in the Mid-Atlantic. Since its inception, it has invested nearly $14 million in more than 50 companies and continues to support the region's entrepreneurial ecosystem.
Made 13 investments in Pennsylvania

New Enterprise Associates

New Enterprise Associates is a United States-based venture capital firm founded in 1977 and headquartered in Menlo Park, California. It invests in technology and healthcare companies across multiple stages, from seed to growth and IPO, and provides strategic support in product development and market expansion. The firm targets sectors including software, AI, consumer technology, digital health, life sciences, and energy technology, and pursues opportunities worldwide. NEA emphasizes long-term partnerships with founders, drawing on domain expertise and a broad network to help portfolio companies scale. It maintains a diverse portfolio across the United States, Asia and other regions, reflecting a global approach to venture investing.
Made 38 investments in Pennsylvania

First Round Capital

First Round Capital is a San Francisco-based venture capital firm focused on pre-seed, seed, and early-stage investments in technology, healthcare, and consumer sectors. It aims to build a community of technology entrepreneurs and provides founder-focused services to help companies grow from inception, including hands-on involvement and networking opportunities. The firm has offices in San Francisco and New York and typically makes initial investments around $500,000, with a track record of helping portfolio companies raise follow-on capital and advance to later rounds. Notable portfolio companies include Uber, Square, and Warby Parker.
Made 30 investments in Pennsylvania

Riverfront Ventures

Riverfront Ventures is the venture arm of Innovation Works, based in Pittsburgh, Pennsylvania. Established in 2013, it pursues seed and early-stage investments in Pennsylvania-centered technology companies, with emphasis on software, healthcare, life sciences, robotics, and related sectors. The firm backs startups that have demonstrated market potential, offering initial funding and follow-on support to accelerate growth. Through its ties to Innovation Works' accelerators and a broad network of partners, Riverfront Ventures helps portfolio companies with mentorship, strategic collaborations, and access to talent and capital, aiming to create high-quality jobs and regional tech leadership in the Pittsburgh area.
Made 12 investments in Pennsylvania

Founders Fund

Founders Fund is a San Francisco-based venture capital firm that invests in science and technology companies across all stages, with a focus on transformational technologies and long-term impact. It backs startups addressing difficult problems in sectors such as aerospace, artificial intelligence, energy, information technology, software, advanced manufacturing and defense-related tech, and it emphasizes a founder-friendly approach that provides support with minimal interference. The firm has backed prominent companies including SpaceX, Palantir, Facebook and Airbnb, reflecting a history of early backing for high-growth ventures. Founders Fund seeks global opportunities and partners with entrepreneurs to navigate rapid technological change, from seed to growth investments.
Made 11 investments in Pennsylvania

Keiretsu Forum

Keiretsu Forum is a global invitation-only network of accredited private equity investors, angel investors and corporate or institutional financiers, organized to connect capital with growth-focused companies. Through chapters worldwide, it links entrepreneurs with capital and strategic resources, hosting selective presentations to generate deal flow and investment opportunities. Members join by invitation and review opportunities collectively but make individual investment decisions, enabling collaboration while preserving autonomy. Keiretsu Forum emphasizes rigorous due diligence and a disciplined screening process, with activity across sectors such as technology, healthcare and life sciences, clean tech, consumer products and real estate. By pooling capital and expertise, it aims to support high-growth companies and foster mutually beneficial partnerships across markets.
Made 19 investments in Pennsylvania

Activate Venture Partners

Activate Venture Partners is a New York-based venture capital firm focusing on seed, early-stage, and growth investments in technology-enabled services and software-driven businesses. The firm backs digital health, healthcare IT and services, fintech, data-as-a-service, enterprise technology, digital media, and related sectors, with an emphasis on software and data services for providers, payors, biopharmaceutical firms, and patients. It does not invest in medical devices or drugs. The firm targets companies in the Greater New York metropolitan area and the Northeast and Mid-Atlantic regions, typically making initial investments in the mid to low single millions and supporting follow-on funding, often leading or co-leading rounds and seeking board seats. Founded in 1999 as Milestone Venture Partners, it maintains headquarters in New York, with an additional office in Bethlehem, Pennsylvania.
Made 9 investments in Pennsylvania

US Innovative Technology Fund

US Innovative Technology Fund is a Pittsburgh-based venture capital firm that provides capital and strategic support to early- and growth-stage technology companies across the United States. Founded in 2022, the firm targets sectors including defense technology, artificial intelligence and machine learning, cybersecurity, information technology, quantum computing, space technology, biotechnology, logistics, and related business products and services, with emphasis on ventures pursuing commercial and defense applications.
Made 2 investments in Pennsylvania

Drive Capital

Drive Capital is a Columbus, Ohio-based venture capital firm founded in 2012 that backs early-stage technology companies across North America, with a focus on the Midwest. It invests in sectors such as software, information technology, healthcare, fintech, and consumer, including SaaS, robotics, AI, and mobile. The firm pursues a hands-on, conviction-based approach, partnering with founders to accelerate growth by leveraging local talent and customer bases, and aims to help portfolio companies become market-defining businesses. Drive Capital manages multiple funds and operates with a broad geographic reach, supporting entrepreneurs from seed through growth stages.
Made 9 investments in Pennsylvania

412 Venture Fund

412 Venture Fund is a venture capital firm based in Pittsburgh, Pennsylvania, founded in 2019. It concentrates on early-stage technology and technology-enabled companies across the United States, with emphasis on artificial intelligence and machine learning, B2B software-as-a-service, cybersecurity, robotics, advanced materials, sensors, healthcare IT, and fintech. The firm typically participates in convertible security or equity rounds, ranging from approximately $250,000 to $2,000,000, and can act as lead, co-lead, or follow-on investor. Beyond capital, it provides strategic guidance and access to a network of industry experts, supporting talent acquisition, strategic development, and negotiation. Led by experienced entrepreneurs and operators, it seeks long-term partnerships with founders who have product-to-market traction and a clear growth path.
Made 5 investments in Pennsylvania

SeventySix Capital

SeventySix Capital is a U.S.-based venture capital firm focused on sports technology and sports-consumer sectors, including esports, sports betting, data analytics, and related media. Based in King of Prussia, Pennsylvania, it invests in early-stage and growth opportunities, often taking leadership roles and seeking board seats. The firm operates a multi-platform approach comprising sports investment funds, sports advisory services, an Athlete Venture Group, and a talent and media arm that connects athletes with portfolio companies. It provides capital, strategic guidance, and access to athlete networks, aiming to bridge athletes, investors, and tech innovators in the sports ecosystem. Founded in 1999, the firm emphasizes technology, data and analytics to unlock the large addressable market in sports.
Made 7 investments in Pennsylvania

OrbiMed

OrbiMed is a global healthcare-focused investment firm founded in 1989 and headquartered in New York. It manages assets across public and private markets and pursues opportunities across the healthcare spectrum, including biopharmaceuticals, medical devices, diagnostics, digital health, and health services. The firm invests in startups, growth-stage companies, and established entities, leveraging scientific and medical expertise to support development and commercialization. It also offers financing solutions such as structured debt and royalty monetization for intellectual property and medical diagnostics.
Made 10 investments in Pennsylvania

Mana Ventures

Mana Ventures is a San Francisco-based venture capital firm founded in 2016 that invests in early-stage artificial intelligence and deep-tech companies across sectors such as AI software, space, healthtech, biotech, robotics, and autonomy. It provides hands-on support to portfolio companies, helping them prepare for funding rounds, scale product and business development, and connect with strategic investors and potential customers. The firm operates The Collective, a value-add network of founders, investors, executives, and specialists that supports portfolio growth. Mana Ventures also curates deal flow and updates through a newsletter, highlighting notable funding milestones and opportunities for ambitious founders.
Made 2 investments in Pennsylvania

Eli Lilly and Company

Eli Lilly and Company is a global pharmaceutical company focused on discovering, developing, manufacturing, and marketing medicines across neuroscience, cardiometabolic, cancer, and immunology areas. It operates manufacturing and distribution facilities in the United States, Puerto Rico, and about 25 other countries, with products sold in roughly 135 countries. The company emphasizes ongoing research to create therapies that address unmet medical needs and to improve patient outcomes. Its portfolio spans treatments for diabetes and metabolic conditions, cancer, autoimmune diseases, and other serious conditions.
Made 13 investments in Pennsylvania

Ground Up Ventures

Ground Up Ventures is a venture capital firm founded in 2017 and based in Philadelphia, Pennsylvania, that invests in early-stage startups, including pre-seed and seed rounds, primarily in the United States and Israel. The firm concentrates on technology sector companies and takes a hands-on, partner-like approach to supporting portfolio teams, offering strategic guidance, operational assistance, and valuable introductions. Founders report proactive involvement, credibility, and responsiveness from Ground Up, with the firm acting as an extension of the founding team to help accelerate progress and execute on their vision.
Made 1 investment in Pennsylvania

Fusion Fund

Fusion Fund is a Palo Alto, California-based venture capital firm founded in 2014 that concentrates on early-stage technology startups across the United States and Canada. It primarily backs pre-seed, seed, and Series A companies, with emphasis on healthcare technology, enterprise AI, industrial technology, information technology, IoT, robotics, drones, cybersecurity, and related sectors. The firm leverages its technical and entrepreneurial background to support portfolio companies with value-added guidance, including access to a CXO Network of experienced executives. Fusion Fund seeks companies with strong technical barriers and potential for global disruption, and provides capital and strategic support to help navigate early growth and scale opportunities.
Made 10 investments in Pennsylvania

Rittenhouse Ventures

Rittenhouse Ventures is a Pennsylvania-based venture capital firm focused on investing in capital-efficient emerging technology companies across the Mid-Atlantic. Headquartered in Wayne, Pennsylvania, with activity in Philadelphia, it targets early-stage rounds in B2B software, healthcare technology, pharmaceutical IT, digital media, financial services IT, and technology-enabled services. The firm emphasizes strategic and operational support and leverages a network of strategic and regional investors to help portfolio companies scale and achieve durable outcomes. Its sector focus includes healthcare, digital media, SaaS, and related areas, with portfolio companies operating in telemedicine, AI-driven solutions, commercial intelligence, and manufacturing software.
Made 10 investments in Pennsylvania

MissionOG

MissionOG is a Philadelphia-based venture capital firm that partners with high-growth B2B companies in fintech, data, AI, and software, typically seeking to invest five to ten million dollars and provide follow-on capital as needed, backed by a broad network of industry experts and hands-on operational guidance drawn from the firm’s experience helping portfolio companies scale to acquisitions.
Made 9 investments in Pennsylvania

Cerity Partners

Cerity Partners is a national independent financial advisory firm that provides investment advisory, wealth management, and comprehensive financial planning services to individuals, families, businesses, employees, and nonprofit organizations from offices across the United States. The firm offers retirement planning, estate and gift planning, tax planning and preparation, insurance planning and risk management, and business owner advisory and executive financial counseling. Cerity Partners emphasizes objective, client-centric guidance and leverages technology platforms, including Addepar and Orion, to enhance client service delivery.
Made 2 investments in Pennsylvania

The Robotics Hub

The Robotics Hub is a Pittsburgh-based venture capital firm founded in 2015 with national reach that invests in information technology, manufacturing, robotics, drones, artificial intelligence, and machine learning. It emphasizes actively creating companies from robotics breakthroughs by rapidly identifying viable ideas, concentrating resources, and advancing them to growth, while providing hands-on support closer to that of a cofounder than a typical investor.
Made 6 investments in Pennsylvania

IP Group

IP Group is a global investment company that backs science- and technology-based ventures by commercialising intellectual property generated at research-intensive institutions. It manages the entire process from identifying suitable IP to developing companies or forming commercial partnerships, leveraging deep industry and financial insight to accelerate value creation for portfolio companies, partners, and investors. The firm concentrates on healthtech, deeptech, and cleantech sectors, providing capital, strategic guidance, and operational support to help translate scientific innovations into scalable businesses. IP Group collaborates with universities, superannuation funds, and corporations to build world-class companies and deploy capital across early-stage and growth opportunities. Notable initiatives include the Climate Catalyst Fund, launched with CEFC to scale decarbonisation technologies, reflecting a track record of pursuing sustainable impact alongside financial return.
Made 11 investments in Pennsylvania

New Rhein Healthcare

New Rhein Healthcare is a Philadelphia-based venture capital firm focused on healthcare therapeutics and medical devices. The firm operates with a global footprint, maintaining offices in Philadelphia and Mechelen, Belgium, and pursues investments in the United States and Europe. It backs companies that leverage proven products in new indications, dosage forms, or applications, and supports portfolio firms with development, regulatory, reimbursement, marketing, and contract manufacturing expertise. The team comprises former industry executives with operational and transactional experience who seek to build value through strategic partnerships and meaningful clinical and commercial progress. The firm emphasizes later-stage, de-risked assets with demonstrated safety and efficacy and aims for strategic exits that deliver health benefits and economic value for investors.
Made 2 investments in Pennsylvania

Maverick Capital

Maverick Capital is a global investment firm founded in 1993 with offices in New York, San Francisco, London, Hong Kong, Philadelphia and Dallas. It invests across public equities and private markets, including Maverick Ventures, the venture arm that backs early to growth stage companies in healthcare, software and deep technology and frequently leads rounds and takes board seats. The firm operates Maverick Silicon, a dedicated semiconductor platform. With a focus on fundamental research, Maverick Capital partners with portfolio teams to build businesses and seeks to preserve and grow capital for its clients. The firm supports a diverse investor base and has built a long history of investing in disruptive technologies across geographies.
Made 2 investments in Pennsylvania