Integrated Reality Labs
Funding Round in 2025
Integrated Reality Labs (IRL Inc.) specializes in developing integrated reality (IR) games and tools that enhance real-world play. Their patent-pending Integrated Reality Technology Platform uses Ultra-Wideband, Bluetooth, mobile location services, and other device sensors to power products like SLAP, a mobile app that transforms classic games like Assassin, HvZ, and Tag into more engaging and accessible experiences. IRL Inc. aims to empower users to create, share, and monetize their own mobile-powered real-world games, similar to the user-generated content model of Roblox.
Vessl Prosthetics
Pre Seed Round in 2025
Vessl Prosthetics is a company dedicated to improving the lives of amputees. It specializes in developing innovative, affordable, and accessible prosthetic solutions. The firm's flagship product is an automatically adjusting prosthetic socket, designed to redistribute pressure around the leg in response to changes in limb size. This technology allows for a more comfortable and secure fit, enabling users to wear their prosthetics according to their specific body needs. Vessl Prosthetics is driven by a mission to empower amputees and their supporters, aiming to revolutionize how prosthetic devices are used.
BrilliantPad
Funding Round in 2024
BrilliantPet introduces smart self-cleaning dog potty. The product is an automatic, convenient and self-cleaning indoor waste disposal product for dogs. They provide a more convenient and healthier potty solution that brings peace of mind to dogs and pet parents.
Virion Therapeutics
Funding Round in 2024
Virion Therapeutics, established in 2018 and based in Newark, Delaware, is a biotechnology company focused on developing immune-based treatments for virally-associated cancers and chronic viral infections. The company's primary products are ChiVax and ChiVax-gD vaccines, designed to induce potent and sustained T cell-mediated immune responses against transformed or infected cells. These vaccines have demonstrated promising results in pre-clinical testing and are poised for translation into clinical trials targeting diseases such as HPV-induced cancers and chronic Hepatitis B infections.
Vytala
Pre Seed Round in 2024
Vytala is a food technology company specializing in enhancing nutrition through innovative solutions. It operates a clinical nutrition business, offering structured lipid technology that improves nutrient absorption, particularly for those with fat malabsorption issues. This technology helps clients avoid nutrient deficiencies, gastrointestinal diseases, and chronic malnutrition, supporting overall health and well-being.
Accencio
Funding Round in 2024
Accencio is an intellectual property strategy and intelligence company specializing in the molecular-based industry and research. It develops a comprehensive IP intelligence platform that provides clients with a multi-level understanding of their targeted intellectual property landscape. The platform enables the identification of strategic opportunities and potential threats within molecular science. Accencio's offerings include interactive visualizations, detailed analysis, and consulting services, all aimed at delivering crucial insights for effective decision-making in research and development, patenting, and licensing. By leveraging its tools and expertise, Accencio supports clients in navigating the complexities of intellectual property rights, ultimately enhancing their ability to address key business challenges efficiently and cost-effectively.
Ophidion
Funding Round in 2024
Ophidion is a biotechnology company focused on developing therapeutics for central nervous system disorders, particularly neurodegenerative diseases such as Alzheimer's, Parkinson's, and Huntington's disease. Utilizing a Trojan horse strategy, the company exploits an endogenous receptor-mediated transport system to deliver small molecule drugs and biologics directly into the brain. Ophidion specializes in gene-silencing therapies, including oligonucleotides and small interfering ribonucleic acids (siRNAs), which can be administered intravenously. In addition to its core focus on neurodegenerative diseases, Ophidion is advancing an innovative program aimed at treating anxiety-related disorders, which includes a patented companion biomarker diagnostic to optimize patient selection for treatment. The company's platform technology is versatile, capable of delivering various classes of drugs, including macromolecules like gene therapeutics, antibodies, and peptides, positioning Ophidion at the forefront of therapeutic advancements in CNS treatment.
Epoxy.ai
Funding Round in 2024
Epoxy.ai is a technology company that specializes in sports personalization, providing tools designed to enhance customer engagement and retention within the sports media and gaming sectors. The company leverages artificial intelligence and machine learning to offer contextually relevant data and insights. Its solutions comprise plug-and-play components and a suite of application programming interfaces (APIs) that are easily integrated into existing systems. This technology enables media and gaming companies to discover actionable user personas and optimize customer interactions across various touchpoints. By automating complex workflows, Epoxy.ai helps clients improve acquisition strategies and content discovery, ultimately fostering growth and evolution within the industry.
Fuego
Funding Round in 2024
Fuego is a global brand specializing in dance-inspired athleisure footwear, particularly known for its patented sneakers designed for both performance and everyday wear. The company’s innovative shoe technology caters to dancers, featuring flexible, minimalistic designs that are lightweight, shock-absorbing, vegan, and water-resistant. Fuego's sneakers are popular in 120 countries and are suitable for various surfaces, making them ideal for dance studios and casual outings alike. The brand has gained recognition through collaborations with notable dancers such as Jade Chynoweth, BDash, and ATACA, further solidifying its reputation in the dance community.
S2N Health
Seed Round in 2024
S2N Health is a strategic consulting firm that specializes in providing business and marketing strategy support to the medical technology sector. Established in 2011, the company has partnered with over 160 organizations, from startups to large global firms, delivering insights and analytics that inform critical product, commercial, and business decisions. S2N Health offers a comprehensive range of services throughout various phases of development, including market entry, sales acceleration, and strategic partnerships. In 2022, the firm launched RepSignal, an AI-driven SaaS solution designed to furnish medtech commercial teams with real-time customer insights and intelligence, enhancing their ability to effectively target and engage clinical customers. By leveraging a network of experts across regulatory, reimbursement, and other disciplines, S2N Health aims to empower healthcare companies to achieve growth and success in a competitive landscape.
FEMSelect
Convertible Note in 2024
FEMSelect Inc., founded in 2012, is a medical device company focused on improving women's health through innovative surgical solutions. Based in Newark, Delaware, FEMSelect develops minimally-invasive and mesh-free systems for pelvic floor ligament fixation. Their flagship product, EnPlace, is designed to treat pelvic organ prolapse (POP) by precisely guiding, inserting, and deploying an anchor unit through the vaginal wall to stabilize the pelvic floor ligament. The procedure typically takes around 30 minutes and does not require overnight hospital stays or result in significant scarring.
BiologicsMD
Corporate Round in 2024
BiologicsMD, Inc. is a therapeutic development company based in Fayetteville, Arkansas, founded in 2010. The company specializes in creating targeted therapies for hair loss conditions and severe bone disorders. It is developing a portfolio of protein therapeutics and drug/device combination products that focus on the PTH/PTHrP receptor to enhance therapeutic effects. Notable products in its pipeline include BMD-1141, designed to stimulate hair growth and prevent hair loss by activating the hair cycle, and BMD-1231, a bone graft substitute intended for spinal fusion procedures as an alternative to autologous bone grafts. BiologicsMD aims to provide sustained therapeutic exposure with its recombinant fusion proteins, allowing for effective treatment with less frequent dosing.
Burrow
Convertible Note in 2024
Burrow, Inc. is a New York-based company that designs, manufactures, and supplies luxury furniture for residential use. Founded in 2016, Burrow specializes in creating easy-to-move and customizable seating options such as sofas, sectionals, loveseats, and armchairs, as well as tables, rugs, and various accessories. The furniture is crafted from sustainably-sourced hardwood and features non-toxic, scratch- and stain-resistant fabrics. Burrow aims to provide customers with comfortable and stylish furnishing alternatives while avoiding traditional retail markups. The company operates showrooms in several states, including Washington, Massachusetts, Texas, and California, and also sells its products online. Additionally, Burrow has a manufacturing facility located in Mexico City, Mexico.
Deepwave Digital
Convertible Note in 2024
Deepwave Digital, Inc. specializes in manufacturing artificial intelligence-based hardware and software sensor solutions tailored for radio frequency (RF) and wireless system applications. Founded in 2017 and headquartered in Philadelphia, Pennsylvania, the company provides integrated solutions that facilitate the incorporation of AI into RF systems. Their flagship product, the Artificial Intelligence Radio Transceiver (AIR-T), is a software-defined radio, complemented by software offerings such as AirPack, AirStack Sandbox, and Spectrum Sensing. These products enable RF and wireless systems to effectively receive, detect, and identify signals within the spectral environment. By positioning the AI computation engine at the signal edge of the RF system, Deepwave Digital aims to minimize network bandwidth, reduce latency, and lessen the reliance on human-driven analysis, thereby delivering cost-effective, high-performance computing solutions to both commercial and defense sectors. The team comprises RF industry experts with extensive experience in digital signal processing.
Proscia Inc., established in 2014 and headquartered in Philadelphia, Pennsylvania, specializes in digital pathology informatics through its innovative cloud-based platform. This platform aids in routine pathology operations, enhances cancer diagnosis, and seeks to improve patient outcomes. By leveraging advanced computing technologies, Proscia's solution unlocks hidden data that is not discernible to the human eye, transforming that information into valuable insights. These insights support physicians in accelerating the development of life-saving medical advances, ultimately contributing to a more effective diagnostic process in the field of pathology.
Biomeme
Convertible Note in 2024
Biomeme Inc. is a biotechnology company based in Philadelphia, Pennsylvania, founded in 2012. It specializes in molecular DNA diagnostics and real-time disease tracking through a user-friendly platform that integrates with smartphones. The company's flagship product is a real-time PCR thermocycler that connects to an iPhone, allowing for on-site DNA diagnostics and disease surveillance. This system comprises a docking station for conducting real-time quantitative PCR, a mobile application to control the device and analyze results, and specific test kits designed to prepare samples and identify pathogens based on their unique DNA or RNA signatures. Biomeme's platform supports various applications including healthcare, agriculture, veterinary medicine, and environmental monitoring, enabling users to perform lab-grade molecular testing conveniently at the point of need.
GABA Therapeutics
Funding Round in 2024
GABA Therapeutics is focused on the development of GRX-917, a medication designed to treat anxiety and depression, as well as a variety of neuropsychiatric and neurological disorders. The drug features a dual mechanism of action that offers rapid onset and efficacy comparable to traditional benzodiazepines, while minimizing side effects. This innovative approach aims to provide relief for patients suffering from life-altering conditions, enhancing their quality of life by addressing both mental and neurological challenges.
OcuTerra Therapeutics
Convertible Note in 2024
OcuTerra Therapeutics, Inc., established in 2017, specializes in developing innovative ophthalmic drugs aimed at treating diseases where current treatments fail to prevent or control progression. Their flagship product is a novel eye drop designed to treat diabetic eye disease by inhibiting integrins for targeted delivery to the back of the eye, with the goal of preventing vision loss.
Vesteck
Convertible Note in 2024
Vesteck is a clinical stage medical device company dedicated to developing innovative solutions for the treatment of aortic aneurysms and related conditions. The company specializes in proprietary technology aimed at the aortic repair, structural heart, and gastrointestinal markets. Its flagship product, the Suture-Tight™ nitinol suture delivery catheter, introduces a novel approach to endovascular aortic repair. This technology addresses critical challenges faced by physicians and patients by securely suturing endovascular grafts to the aorta during initial implants or repairs. Additionally, Vesteck's advancements aim to minimize issues such as graft migration and leaks, which can lead to complex and costly interventions. Through its focus on enhancing patient care and improving outcomes, Vesteck is positioned to make a significant impact in the medical device industry.
BrilliantPad
Convertible Note in 2024
BrilliantPet introduces smart self-cleaning dog potty. The product is an automatic, convenient and self-cleaning indoor waste disposal product for dogs. They provide a more convenient and healthier potty solution that brings peace of mind to dogs and pet parents.
Illumina Radiopharmaceuticals
Venture Round in 2023
Illumina Radiopharmaceuticals
Medcura
Convertible Note in 2023
Medcura, Inc. is a company that specializes in the development of advanced hemostatic products for various applications, including surgical, military, and consumer settings. Based in Riverdale, Maryland, Medcura has created a versatile wound care platform that utilizes abundant natural materials to produce innovative products for managing significant surgical bleeds. The company's offerings, marketed under brand names such as R3, Medcura Flex, LifeFoam, and Surgicura, include solutions that not only control bleeding but also provide antibacterial barriers, promoting enhanced healing environments. Founded in 2007 and rebranded from gel-e, Inc. in December 2019, Medcura aims to improve bleeding management in both clinical and non-clinical scenarios.
SessionGuardian
Seed Round in 2023
SessionGuardian is a pioneering company in the field of identity access control and authentication, specifically catering to hybrid teams managing highly sensitive data. The company develops advanced cybersecurity software that provides endpoint security services, focusing on second-by-second biometric identity verification for remote users. This continuous verification process spans from log-on to log-off, allowing businesses to safeguard against data breaches while maintaining an efficient workflow. By combining innovative technology with a commitment to security, SessionGuardian addresses the critical challenges faced by organizations in an increasingly digital and remote work environment.
Fuego
Convertible Note in 2023
Fuego is a global brand specializing in dance-inspired athleisure footwear, particularly known for its patented sneakers designed for both performance and everyday wear. The company’s innovative shoe technology caters to dancers, featuring flexible, minimalistic designs that are lightweight, shock-absorbing, vegan, and water-resistant. Fuego's sneakers are popular in 120 countries and are suitable for various surfaces, making them ideal for dance studios and casual outings alike. The brand has gained recognition through collaborations with notable dancers such as Jade Chynoweth, BDash, and ATACA, further solidifying its reputation in the dance community.
Simply Good Jars
Convertible Note in 2023
Simply Good Jars is a certified B-Corporation dedicated to promoting sustainability through its meal delivery service. The company operates smart refrigerated kiosks in offices, transit centers, universities, and healthcare facilities, offering chef-prepared, ready-to-eat meals packaged in reusable jars. These jars are designed to minimize waste, with a high return rate ensuring minimal environmental impact. For every jar returned, Simply Good Jars contributes to feeding someone in need, aligning its business model with social responsibility.
Epoxy.ai
Seed Round in 2023
Epoxy.ai is a technology company that specializes in sports personalization, providing tools designed to enhance customer engagement and retention within the sports media and gaming sectors. The company leverages artificial intelligence and machine learning to offer contextually relevant data and insights. Its solutions comprise plug-and-play components and a suite of application programming interfaces (APIs) that are easily integrated into existing systems. This technology enables media and gaming companies to discover actionable user personas and optimize customer interactions across various touchpoints. By automating complex workflows, Epoxy.ai helps clients improve acquisition strategies and content discovery, ultimately fostering growth and evolution within the industry.
Wavely Diagnostics
Seed Round in 2023
Wavely Diagnostics is pioneering the future of remote digital diagnostics and enabling telehealth growth by leveraging smartphone technology to address pediatric care.
Verdafresh
Series B in 2023
Verdafresh specializes in the manufacture of innovative packaging solutions aimed at preserving food freshness. The company focuses on mono-material packaging that utilizes barrier coating on films, providing a sustainable alternative to traditional materials. Verdafresh's offerings include flexible packaging and recycling services, allowing clients to extend the shelf life of food products while promoting recyclability. By using natural and abundant materials, Verdafresh delivers a competitive cost solution that addresses both food preservation needs and environmental concerns related to plastic waste.
Ophidion
Convertible Note in 2023
Ophidion is a biotechnology company focused on developing therapeutics for central nervous system disorders, particularly neurodegenerative diseases such as Alzheimer's, Parkinson's, and Huntington's disease. Utilizing a Trojan horse strategy, the company exploits an endogenous receptor-mediated transport system to deliver small molecule drugs and biologics directly into the brain. Ophidion specializes in gene-silencing therapies, including oligonucleotides and small interfering ribonucleic acids (siRNAs), which can be administered intravenously. In addition to its core focus on neurodegenerative diseases, Ophidion is advancing an innovative program aimed at treating anxiety-related disorders, which includes a patented companion biomarker diagnostic to optimize patient selection for treatment. The company's platform technology is versatile, capable of delivering various classes of drugs, including macromolecules like gene therapeutics, antibodies, and peptides, positioning Ophidion at the forefront of therapeutic advancements in CNS treatment.
ChargeItSpot
Series A in 2023
ChargeItSpot, LLC is a company based in Philadelphia, Pennsylvania, founded in 2011. It specializes in providing free and secure cell phone charging stations and kiosks across the United States and Canada. These charging stations are designed with a touchscreen interface, secure locking capability, and promotional features that allow for customizable on-screen messages. ChargeItSpot's services are tailored to enhance sales, foot traffic, and customer loyalty by offering convenient charging solutions in various settings such as retail stores, malls, casinos, stadiums, hospitals, arenas, conferences, trade shows, festivals, and special events. The company’s stations also include data tracking and reporting features, providing valuable insights for business owners.
Hanimune Therapeutics
Seed Round in 2023
Hanimune Therapeutics is a biotechnology company that seeks to prevent and treat food allergies by using nature-based solutions. It is also developing novel treatments for food allergies that utilize the tolerogenic immune system, which is part of the immune system that prevents harmful reactions to harmless substances.
Measure Studio
Seed Round in 2023
Measure Studio operates a content intelligence engine that helps digital publishers, brands, agencies, and influencers develop data-driven social media content strategies. The company's platform allows users to consolidate and analyze their social media data in a secure environment, facilitating informed decision-making for content creation. By providing a turnkey solution for managing analytics across multiple platforms, Measure Studio empowers its clients to enhance their content strategies and improve engagement with their audiences.
Cooler Heads
Venture Round in 2023
Cooler Heads is a company that specializes in developing a portable scalp cooling system aimed at helping chemotherapy patients manage the side effects of their treatment. Their flagship product, Amma™, is designed to cool the scalp during chemotherapy sessions, reducing the likelihood of hair loss. By offering this solution, Cooler Heads empowers cancer patients with more control over their appearance and overall well-being during a challenging time, thereby improving their mental health and recovery process.
Lia
Convertible Note in 2023
LIA Diagnostics Inc. is a company based in Philadelphia, Pennsylvania, that specializes in developing innovative pregnancy test kits. Founded in 2015, the company focuses on addressing key issues associated with traditional pregnancy tests, specifically privacy, usability, and sustainability. LIA's test kits are made from eco-friendly materials, containing no plastic, and are designed to be foldable, flushable, and easy to carry. This design allows users to conduct tests discreetly and conveniently, while also minimizing confusion in test interpretation. By prioritizing sustainability and user experience, LIA Diagnostics aims to redefine the pregnancy testing process for women.
LuxTech
Convertible Note in 2023
LUXTECH, LLC is a Philadelphia-based company that specializes in the design, engineering, and manufacturing of LED module solutions for lighting fixture manufacturers. Incorporated in 2012, LUXTECH focuses on specification-grade LED modules tailored for architectural-grade lighting applications. Its product range includes LINEAR Dynamic White, LINEAR White, COB Warm Dim, COB Dynamic White, and FLEX LED modules and tapes, which cater to various sectors, including entertainment, restaurants, educational institutions, cultural offerings, and healthcare. The company is committed to helping original equipment manufacturers (OEMs) enhance their lighting offerings by providing reliable and energy-efficient LED solutions. LUXTECH’s modules are versatile, supporting applications such as troffers, linear lighting systems, downlights, outdoor area lighting, industrial lighting, and specialty luminaires. With a focus on innovation and rapid product development, LUXTECH can create custom prototypes or retrofit existing fixtures in a short timeframe. The company’s products are built with LM-80 tested components and come with a five-year warranty, ensuring high performance and longevity.
Vesteck
Venture Round in 2023
Vesteck is a clinical stage medical device company dedicated to developing innovative solutions for the treatment of aortic aneurysms and related conditions. The company specializes in proprietary technology aimed at the aortic repair, structural heart, and gastrointestinal markets. Its flagship product, the Suture-Tight™ nitinol suture delivery catheter, introduces a novel approach to endovascular aortic repair. This technology addresses critical challenges faced by physicians and patients by securely suturing endovascular grafts to the aorta during initial implants or repairs. Additionally, Vesteck's advancements aim to minimize issues such as graft migration and leaks, which can lead to complex and costly interventions. Through its focus on enhancing patient care and improving outcomes, Vesteck is positioned to make a significant impact in the medical device industry.
Beckon Ice Cream
Seed Round in 2022
Beckon Ice Cream specializes in producing premium, lactose-free ice cream made from real milk and cream, enhanced with lactase enzyme to ensure it is digestible for those with lactose intolerance. The company prides itself on using only six natural ingredients per pint, avoiding gums, stabilizers, and artificial additives. Beckon offers a variety of flavors, including dark chocolate, peanut butter, vanilla, sea salt chocolate, and mint chip, available in formats such as pints, quarts, and novelties.
Fuego is a global brand specializing in dance-inspired athleisure footwear, particularly known for its patented sneakers designed for both performance and everyday wear. The company’s innovative shoe technology caters to dancers, featuring flexible, minimalistic designs that are lightweight, shock-absorbing, vegan, and water-resistant. Fuego's sneakers are popular in 120 countries and are suitable for various surfaces, making them ideal for dance studios and casual outings alike. The brand has gained recognition through collaborations with notable dancers such as Jade Chynoweth, BDash, and ATACA, further solidifying its reputation in the dance community.
FEMSelect
Series B in 2022
FEMSelect Inc., founded in 2012, is a medical device company focused on improving women's health through innovative surgical solutions. Based in Newark, Delaware, FEMSelect develops minimally-invasive and mesh-free systems for pelvic floor ligament fixation. Their flagship product, EnPlace, is designed to treat pelvic organ prolapse (POP) by precisely guiding, inserting, and deploying an anchor unit through the vaginal wall to stabilize the pelvic floor ligament. The procedure typically takes around 30 minutes and does not require overnight hospital stays or result in significant scarring.
Epoxy.ai
Venture Round in 2022
Epoxy.ai is a technology company that specializes in sports personalization, providing tools designed to enhance customer engagement and retention within the sports media and gaming sectors. The company leverages artificial intelligence and machine learning to offer contextually relevant data and insights. Its solutions comprise plug-and-play components and a suite of application programming interfaces (APIs) that are easily integrated into existing systems. This technology enables media and gaming companies to discover actionable user personas and optimize customer interactions across various touchpoints. By automating complex workflows, Epoxy.ai helps clients improve acquisition strategies and content discovery, ultimately fostering growth and evolution within the industry.
AnaOno is a specialized apparel brand that designs and produces intimates and loungewear specifically for women who have undergone breast surgery, including mastectomy and breast reconstruction. The company focuses on creating unique products that cater to diverse breast shapes and surgical experiences, ensuring comfort and style through wire-free designs made from super soft materials. AnaOno's offerings emphasize feminine details and silhouettes, providing a range of undergarment options that prioritize both functionality and aesthetics for women living with conditions related to breast surgery.
Medcura
Venture Round in 2022
Medcura, Inc. is a company that specializes in the development of advanced hemostatic products for various applications, including surgical, military, and consumer settings. Based in Riverdale, Maryland, Medcura has created a versatile wound care platform that utilizes abundant natural materials to produce innovative products for managing significant surgical bleeds. The company's offerings, marketed under brand names such as R3, Medcura Flex, LifeFoam, and Surgicura, include solutions that not only control bleeding but also provide antibacterial barriers, promoting enhanced healing environments. Founded in 2007 and rebranded from gel-e, Inc. in December 2019, Medcura aims to improve bleeding management in both clinical and non-clinical scenarios.
SessionGuardian
Seed Round in 2022
SessionGuardian is a pioneering company in the field of identity access control and authentication, specifically catering to hybrid teams managing highly sensitive data. The company develops advanced cybersecurity software that provides endpoint security services, focusing on second-by-second biometric identity verification for remote users. This continuous verification process spans from log-on to log-off, allowing businesses to safeguard against data breaches while maintaining an efficient workflow. By combining innovative technology with a commitment to security, SessionGuardian addresses the critical challenges faced by organizations in an increasingly digital and remote work environment.
Thermalin
Venture Round in 2022
Thermalin, Inc. is a biotechnology company based in Cleveland, Ohio, founded in 2010, that focuses on developing innovative insulin therapies for individuals with Type 1 and Type 2 diabetes. The company aims to transform the insulin and insulin delivery market, valued at $30 billion, through its cutting-edge, highly concentrated, ultra-rapid acting insulin and a novel glucose management system that is the size of a postage stamp. This insulin can also be utilized in existing insulin pumps, enhancing their efficiency. In addition to its lead program, Thermalin is exploring partnerships to create no-cold-chain basal and mix insulins, as well as glucose-responsive insulins. Its products are designed to be rapidly absorbing and do not require refrigeration, thereby reducing the burden of insulin therapy and improving patient adherence and health outcomes.
Illumina Radiopharmaceuticals
Venture Round in 2022
Illumina Radiopharmaceuticals
BiologicsMD
Venture Round in 2022
BiologicsMD, Inc. is a therapeutic development company based in Fayetteville, Arkansas, founded in 2010. The company specializes in creating targeted therapies for hair loss conditions and severe bone disorders. It is developing a portfolio of protein therapeutics and drug/device combination products that focus on the PTH/PTHrP receptor to enhance therapeutic effects. Notable products in its pipeline include BMD-1141, designed to stimulate hair growth and prevent hair loss by activating the hair cycle, and BMD-1231, a bone graft substitute intended for spinal fusion procedures as an alternative to autologous bone grafts. BiologicsMD aims to provide sustained therapeutic exposure with its recombinant fusion proteins, allowing for effective treatment with less frequent dosing.
Proscia Inc., established in 2014 and headquartered in Philadelphia, Pennsylvania, specializes in digital pathology informatics through its innovative cloud-based platform. This platform aids in routine pathology operations, enhances cancer diagnosis, and seeks to improve patient outcomes. By leveraging advanced computing technologies, Proscia's solution unlocks hidden data that is not discernible to the human eye, transforming that information into valuable insights. These insights support physicians in accelerating the development of life-saving medical advances, ultimately contributing to a more effective diagnostic process in the field of pathology.
Atrin Pharmaceuticals
Venture Round in 2022
Atrin Pharmaceuticals LLC is a biopharmaceutical company based in Doylestown, Pennsylvania, that focuses on the discovery and development of innovative cancer treatments. Founded in 2011, Atrin is dedicated to transforming cancer therapy through its advanced drug candidates, including ATRN-502, a p53 activator, and ATRN-507, a dual ligand designed to selectively target cancer cells. The company utilizes its proprietary high-throughput screening platform, Atrize, which enables the identification and evaluation of compounds that effectively inhibit cancer cell viability while sparing healthy cells. Atrin's approach centers on addressing cancers associated with synthetic lethality and deregulated DNA damage response, with the goal of providing effective and safe therapeutic options for patients.
ChargeItSpot
Venture Round in 2022
ChargeItSpot, LLC is a company based in Philadelphia, Pennsylvania, founded in 2011. It specializes in providing free and secure cell phone charging stations and kiosks across the United States and Canada. These charging stations are designed with a touchscreen interface, secure locking capability, and promotional features that allow for customizable on-screen messages. ChargeItSpot's services are tailored to enhance sales, foot traffic, and customer loyalty by offering convenient charging solutions in various settings such as retail stores, malls, casinos, stadiums, hospitals, arenas, conferences, trade shows, festivals, and special events. The company’s stations also include data tracking and reporting features, providing valuable insights for business owners.
Vertiq specializes in the development of high-performance propulsion solutions for aerial vehicles and mobile robots. The company’s core product features a lightweight, integrated motor and electronic speed controller (ESC) that includes an embedded position sensor. This innovative design, combined with advanced motor calibration and control software, provides significant performance benefits, such as extended flight duration, improved maneuverability, and enhanced reliability. By optimizing motor performance and controllability, Vertiq enables clients to significantly enhance the capabilities of their vehicles, making it a key player in the propulsion systems market.
Simply Good Jars
Seed Round in 2022
Simply Good Jars is a certified B-Corporation dedicated to promoting sustainability through its meal delivery service. The company operates smart refrigerated kiosks in offices, transit centers, universities, and healthcare facilities, offering chef-prepared, ready-to-eat meals packaged in reusable jars. These jars are designed to minimize waste, with a high return rate ensuring minimal environmental impact. For every jar returned, Simply Good Jars contributes to feeding someone in need, aligning its business model with social responsibility.
Burrow, Inc. is a New York-based company that designs, manufactures, and supplies luxury furniture for residential use. Founded in 2016, Burrow specializes in creating easy-to-move and customizable seating options such as sofas, sectionals, loveseats, and armchairs, as well as tables, rugs, and various accessories. The furniture is crafted from sustainably-sourced hardwood and features non-toxic, scratch- and stain-resistant fabrics. Burrow aims to provide customers with comfortable and stylish furnishing alternatives while avoiding traditional retail markups. The company operates showrooms in several states, including Washington, Massachusetts, Texas, and California, and also sells its products online. Additionally, Burrow has a manufacturing facility located in Mexico City, Mexico.
LIA Diagnostics Inc. is a company based in Philadelphia, Pennsylvania, that specializes in developing innovative pregnancy test kits. Founded in 2015, the company focuses on addressing key issues associated with traditional pregnancy tests, specifically privacy, usability, and sustainability. LIA's test kits are made from eco-friendly materials, containing no plastic, and are designed to be foldable, flushable, and easy to carry. This design allows users to conduct tests discreetly and conveniently, while also minimizing confusion in test interpretation. By prioritizing sustainability and user experience, LIA Diagnostics aims to redefine the pregnancy testing process for women.
Beckon Ice Cream
Seed Round in 2022
Beckon Ice Cream specializes in producing premium, lactose-free ice cream made from real milk and cream, enhanced with lactase enzyme to ensure it is digestible for those with lactose intolerance. The company prides itself on using only six natural ingredients per pint, avoiding gums, stabilizers, and artificial additives. Beckon offers a variety of flavors, including dark chocolate, peanut butter, vanilla, sea salt chocolate, and mint chip, available in formats such as pints, quarts, and novelties.
Cooler Heads
Seed Round in 2021
Cooler Heads is a company that specializes in developing a portable scalp cooling system aimed at helping chemotherapy patients manage the side effects of their treatment. Their flagship product, Amma™, is designed to cool the scalp during chemotherapy sessions, reducing the likelihood of hair loss. By offering this solution, Cooler Heads empowers cancer patients with more control over their appearance and overall well-being during a challenging time, thereby improving their mental health and recovery process.
BrilliantPad
Series D in 2021
BrilliantPet introduces smart self-cleaning dog potty. The product is an automatic, convenient and self-cleaning indoor waste disposal product for dogs. They provide a more convenient and healthier potty solution that brings peace of mind to dogs and pet parents.
Vesteck is a clinical stage medical device company dedicated to developing innovative solutions for the treatment of aortic aneurysms and related conditions. The company specializes in proprietary technology aimed at the aortic repair, structural heart, and gastrointestinal markets. Its flagship product, the Suture-Tight™ nitinol suture delivery catheter, introduces a novel approach to endovascular aortic repair. This technology addresses critical challenges faced by physicians and patients by securely suturing endovascular grafts to the aorta during initial implants or repairs. Additionally, Vesteck's advancements aim to minimize issues such as graft migration and leaks, which can lead to complex and costly interventions. Through its focus on enhancing patient care and improving outcomes, Vesteck is positioned to make a significant impact in the medical device industry.
Medcura, Inc. is a company that specializes in the development of advanced hemostatic products for various applications, including surgical, military, and consumer settings. Based in Riverdale, Maryland, Medcura has created a versatile wound care platform that utilizes abundant natural materials to produce innovative products for managing significant surgical bleeds. The company's offerings, marketed under brand names such as R3, Medcura Flex, LifeFoam, and Surgicura, include solutions that not only control bleeding but also provide antibacterial barriers, promoting enhanced healing environments. Founded in 2007 and rebranded from gel-e, Inc. in December 2019, Medcura aims to improve bleeding management in both clinical and non-clinical scenarios.
OcuTerra Therapeutics
Series B in 2021
OcuTerra Therapeutics, Inc., established in 2017, specializes in developing innovative ophthalmic drugs aimed at treating diseases where current treatments fail to prevent or control progression. Their flagship product is a novel eye drop designed to treat diabetic eye disease by inhibiting integrins for targeted delivery to the back of the eye, with the goal of preventing vision loss.
Intrommune Therapeutics
Series A in 2021
Intrommune Therapeutics is a clinical-stage biotechnology company focused on developing innovative treatments for food allergies. It aims to provide safe and effective options for individuals suffering from these conditions through its Oral Mucosal Immunotherapy (OMIT) platform. This platform utilizes a specially formulated toothpaste that integrates allergenic proteins into daily dental hygiene, allowing patients to retrain their immune systems while maintaining oral care. The company's lead product, INT301, targets peanut allergies, addressing a significant unmet need in a market where few effective treatments exist. Current options are limited and often involve risky procedures that deter patients from engaging. Intrommune's approach offers a promising alternative, enabling patients and their families to manage food allergies more effectively. The company is currently conducting a Phase 1b study for INT301, with key development milestones anticipated in the coming year.
Sonnest is a clinical healthcare company focused on developing innovative solutions for the myocardium. It specializes in an electrically sensitive imaging agent that assesses and monitors the heart's perfusion, structure, and function. This voltage-activated agent responds to ultrasound and the local electric field of the heart, allowing clinicians to determine the viability of heart tissue. By providing advanced imaging technology, Sonnest aims to enhance patient care and improve health outcomes. Additionally, the company addresses customer inquiries through various channels, including phone, email, and online applications, ensuring accessible support for its clients.
Deepwave Digital
Seed Round in 2020
Deepwave Digital, Inc. specializes in manufacturing artificial intelligence-based hardware and software sensor solutions tailored for radio frequency (RF) and wireless system applications. Founded in 2017 and headquartered in Philadelphia, Pennsylvania, the company provides integrated solutions that facilitate the incorporation of AI into RF systems. Their flagship product, the Artificial Intelligence Radio Transceiver (AIR-T), is a software-defined radio, complemented by software offerings such as AirPack, AirStack Sandbox, and Spectrum Sensing. These products enable RF and wireless systems to effectively receive, detect, and identify signals within the spectral environment. By positioning the AI computation engine at the signal edge of the RF system, Deepwave Digital aims to minimize network bandwidth, reduce latency, and lessen the reliance on human-driven analysis, thereby delivering cost-effective, high-performance computing solutions to both commercial and defense sectors. The team comprises RF industry experts with extensive experience in digital signal processing.
Beckon Ice Cream
Angel Round in 2020
Beckon Ice Cream specializes in producing premium, lactose-free ice cream made from real milk and cream, enhanced with lactase enzyme to ensure it is digestible for those with lactose intolerance. The company prides itself on using only six natural ingredients per pint, avoiding gums, stabilizers, and artificial additives. Beckon offers a variety of flavors, including dark chocolate, peanut butter, vanilla, sea salt chocolate, and mint chip, available in formats such as pints, quarts, and novelties.
Cooler Heads
Convertible Note in 2020
Cooler Heads is a company that specializes in developing a portable scalp cooling system aimed at helping chemotherapy patients manage the side effects of their treatment. Their flagship product, Amma™, is designed to cool the scalp during chemotherapy sessions, reducing the likelihood of hair loss. By offering this solution, Cooler Heads empowers cancer patients with more control over their appearance and overall well-being during a challenging time, thereby improving their mental health and recovery process.
FEMSelect
Convertible Note in 2020
FEMSelect Inc., founded in 2012, is a medical device company focused on improving women's health through innovative surgical solutions. Based in Newark, Delaware, FEMSelect develops minimally-invasive and mesh-free systems for pelvic floor ligament fixation. Their flagship product, EnPlace, is designed to treat pelvic organ prolapse (POP) by precisely guiding, inserting, and deploying an anchor unit through the vaginal wall to stabilize the pelvic floor ligament. The procedure typically takes around 30 minutes and does not require overnight hospital stays or result in significant scarring.
Beckon
Venture Round in 2020
Beckon, Inc. is a software company specializing in omnichannel analytics for marketers, founded in 2011 and headquartered in San Mateo, California. It offers a software-as-a-service platform that integrates marketing data to provide performance analytics and visualization solutions. Beckon's software delivers real-time marketing intelligence through automated data management, allowing marketers to gain total visibility into cross-channel performance. The platform features pre-built dashboards, scorecards, and key performance indicators, enabling users to make informed decisions swiftly and maximize return on investment. As of November 2018, Beckon operates as a subsidiary of Aclate, Inc. Its goal is to aid marketers in organizing complex data and effectively demonstrating the impact of marketing efforts on business outcomes.
Proscia Inc., established in 2014 and headquartered in Philadelphia, Pennsylvania, specializes in digital pathology informatics through its innovative cloud-based platform. This platform aids in routine pathology operations, enhances cancer diagnosis, and seeks to improve patient outcomes. By leveraging advanced computing technologies, Proscia's solution unlocks hidden data that is not discernible to the human eye, transforming that information into valuable insights. These insights support physicians in accelerating the development of life-saving medical advances, ultimately contributing to a more effective diagnostic process in the field of pathology.
Wash Cycle Laundry
Series A in 2020
Wash Cycle Laundry Inc. is a laundry service provider based in Philadelphia, Pennsylvania, with an additional location in Washington, D.C. Founded in 2012, the company specializes in laundry, linen rental, and dry cleaning services for a diverse clientele, including universities, healthcare institutions, hotels, and individual customers. Wash Cycle Laundry is notable for its environmentally friendly practices, utilizing eco-friendly detergents and non-perc solvents in its cleaning processes. The company offers a range of services, including the washing of clothes, linens, towels, and janitorial supplies, as well as campus laundry plans and managed on-premise laundry services. Their commitment to sustainability and customer service is reflected in their unique bike-based pickup and delivery system, ensuring that clean laundry is returned promptly.
ExpressCells
Venture Round in 2020
ExpressCells, Inc. is a biotechnology company founded in 2018 and headquartered in Philadelphia, Pennsylvania. The company specializes in genetic engineering, focusing on the creation of custom knock-in cell lines tailored for drug discovery and biological research. ExpressCells employs advanced gene-editing technology to make precise modifications to a cell's genome, utilizing a patent-pending plasmid system to introduce new genes. This innovative approach enables researchers to visualize proteins and organelles within the cell, thereby enhancing their ability to model diseases and accelerate drug discovery processes.
Thermalin
Convertible Note in 2020
Thermalin, Inc. is a biotechnology company based in Cleveland, Ohio, founded in 2010, that focuses on developing innovative insulin therapies for individuals with Type 1 and Type 2 diabetes. The company aims to transform the insulin and insulin delivery market, valued at $30 billion, through its cutting-edge, highly concentrated, ultra-rapid acting insulin and a novel glucose management system that is the size of a postage stamp. This insulin can also be utilized in existing insulin pumps, enhancing their efficiency. In addition to its lead program, Thermalin is exploring partnerships to create no-cold-chain basal and mix insulins, as well as glucose-responsive insulins. Its products are designed to be rapidly absorbing and do not require refrigeration, thereby reducing the burden of insulin therapy and improving patient adherence and health outcomes.
Yellowdig
Convertible Note in 2020
Yellowdig is a technology company founded in 2015 and headquartered in Philadelphia, Pennsylvania. It specializes in developing a social learning platform tailored for higher education institutions. The platform enhances existing enterprise learning systems by adding a social layer that fosters peer learning and collaboration among students. By creating a secure and private environment, Yellowdig promotes engaging learning experiences while enabling instructors and learners to interact effectively. The platform not only facilitates knowledge sharing but also encourages student engagement and retention, ultimately transforming traditional classrooms into vibrant collaborative learning communities.
Simply Good Jars
Convertible Note in 2020
Simply Good Jars is a certified B-Corporation dedicated to promoting sustainability through its meal delivery service. The company operates smart refrigerated kiosks in offices, transit centers, universities, and healthcare facilities, offering chef-prepared, ready-to-eat meals packaged in reusable jars. These jars are designed to minimize waste, with a high return rate ensuring minimal environmental impact. For every jar returned, Simply Good Jars contributes to feeding someone in need, aligning its business model with social responsibility.
Biomeme
Convertible Note in 2020
Biomeme Inc. is a biotechnology company based in Philadelphia, Pennsylvania, founded in 2012. It specializes in molecular DNA diagnostics and real-time disease tracking through a user-friendly platform that integrates with smartphones. The company's flagship product is a real-time PCR thermocycler that connects to an iPhone, allowing for on-site DNA diagnostics and disease surveillance. This system comprises a docking station for conducting real-time quantitative PCR, a mobile application to control the device and analyze results, and specific test kits designed to prepare samples and identify pathogens based on their unique DNA or RNA signatures. Biomeme's platform supports various applications including healthcare, agriculture, veterinary medicine, and environmental monitoring, enabling users to perform lab-grade molecular testing conveniently at the point of need.
Genome Profiling
Convertible Note in 2020
Genome Profiling, LLC is a bioinformatics company based in Wayne, Pennsylvania, focused on the discovery of novel epigenetic biomarkers for diagnosing, treating, and predicting chronic and life-threatening diseases. Founded in 2012, the company has developed GenPro Analytics, an innovative software platform that enhances the ability of scientists and medical professionals to predict, diagnose, and monitor disease progression with improved sensitivity, specificity, accuracy, and cost-effectiveness. Genome Profiling offers a unique epigenetic biomarker discovery platform that integrates a proprietary pre-NGS gDNA preparation kit with advanced NGS data analytics algorithms, allowing for efficient incorporation into standard NGS workflows. This technology enables a single NGS run to yield comprehensive genomic variant call analyses alongside epigenetic data, positioning Genome Profiling at the forefront of the rapidly emerging market in genomic and epigenetic research.
ReturnLogic
Seed Round in 2020
ReturnLogic is a leader in returns management, focusing on transforming the returns process for retailers through advanced technology. The company has developed a cloud-based platform that automates and optimizes product returns and associated operations. By leveraging artificial intelligence and an API-first approach, ReturnLogic streamlines the returns process, enhancing visibility and efficiency for e-commerce retailers and brands. Its platform simplifies returns for customers while automating workflows for customer service and warehouse teams, effectively addressing the challenges of retail returns. This innovative solution enables businesses to maximize productivity and improve their overall profitability.
LoanLogics
Convertible Note in 2020
LoanLogics, Inc. is a provider of innovative mortgage loan software products and services aimed at enhancing the efficiency and quality of the mortgage industry. Based in Trevose, Pennsylvania, the company offers several key platforms, including LoanDecisions for product eligibility and mortgage pricing, and LoanHD for real-time loan quality management. Its solutions are designed to automate key processes, thereby reducing loan defects and costs while managing risks in the manufacturing, acquisition, and sale of loan assets. LoanLogics serves a diverse clientele, including residential mortgage lenders, servicers, insurers, and investors, and has established strategic partnerships to enhance its offerings. Founded in 2006 and originally named Aklero Risk Analytics, LoanLogics rebranded in 2013 to reflect its focus on comprehensive mortgage solutions.
FEMSelect
Convertible Note in 2020
FEMSelect Inc., founded in 2012, is a medical device company focused on improving women's health through innovative surgical solutions. Based in Newark, Delaware, FEMSelect develops minimally-invasive and mesh-free systems for pelvic floor ligament fixation. Their flagship product, EnPlace, is designed to treat pelvic organ prolapse (POP) by precisely guiding, inserting, and deploying an anchor unit through the vaginal wall to stabilize the pelvic floor ligament. The procedure typically takes around 30 minutes and does not require overnight hospital stays or result in significant scarring.
Burrow, Inc. is a New York-based company that designs, manufactures, and supplies luxury furniture for residential use. Founded in 2016, Burrow specializes in creating easy-to-move and customizable seating options such as sofas, sectionals, loveseats, and armchairs, as well as tables, rugs, and various accessories. The furniture is crafted from sustainably-sourced hardwood and features non-toxic, scratch- and stain-resistant fabrics. Burrow aims to provide customers with comfortable and stylish furnishing alternatives while avoiding traditional retail markups. The company operates showrooms in several states, including Washington, Massachusetts, Texas, and California, and also sells its products online. Additionally, Burrow has a manufacturing facility located in Mexico City, Mexico.
OWIT Global
Series A in 2020
OWIT Global is a provider of innovative insurance technology solutions aimed at modernizing and streamlining insurance processing for the global insurance industry. Founded in 2018 and headquartered in West Hartford, Connecticut, the company specializes in developing cloud-based microservices that can operate independently or integrate seamlessly with existing systems. OWIT Global has created a versatile library of these microservices, which can be configured to address specific needs within the industry, including Bordereaux Management, Cyber Rating & Distribution, and Document Generation. The company's offerings are designed to enhance operational efficiency, improve data quality across the insurance value chain, and support the adoption of emerging technologies such as blockchain and smart contracts.
Immunome Inc., founded in 2006 and headquartered in Exton, Pennsylvania, is a biotechnology company focused on discovering, developing, and commercializing highly targeted and native human cancer antibodies against universal cancer antigens. The company utilizes its proprietary RealMAb technology to identify novel antigens and the corresponding native human antibodies that target them. Additionally, Immunome employs ScreenMab multiplex functional screening technology to pinpoint monoclonal antibodies with high specificity for tumor neoantigens.
Lia
Convertible Note in 2020
LIA Diagnostics Inc. is a company based in Philadelphia, Pennsylvania, that specializes in developing innovative pregnancy test kits. Founded in 2015, the company focuses on addressing key issues associated with traditional pregnancy tests, specifically privacy, usability, and sustainability. LIA's test kits are made from eco-friendly materials, containing no plastic, and are designed to be foldable, flushable, and easy to carry. This design allows users to conduct tests discreetly and conveniently, while also minimizing confusion in test interpretation. By prioritizing sustainability and user experience, LIA Diagnostics aims to redefine the pregnancy testing process for women.
AgileSwitch
Venture Round in 2020
AgileSwitch, LLC is a Philadelphia-based company that specializes in the design and manufacture of gate drivers for silicon carbide (SiC) power modules. Established in 2011, AgileSwitch focuses on enhancing the performance and efficiency of electric vehicles and renewable energy applications through its innovative technology. The company's product offerings include plug-and-play gate drivers, analog stack electronics, and evaluation kits for both analog and digital intelligent power modules (IPMs). AgileSwitch's gate drivers are recognized for their efficiency and reliability, and they can be fully customized to meet specific customer needs. The company is committed to ongoing product development, continually expanding its range of gate drivers to support various applications such as electric vehicles, solar inverters, wind turbines, energy storage, and motor drives, thereby enabling clients to achieve significant performance improvements and reduced power loss.
Annovis Bio, Inc., established in 2008 and headquartered in Berwyn, Pennsylvania, is a clinical-stage drug development company specializing in therapies for neurodegenerative disorders. Its primary focus is on Alzheimer's disease (AD) and Parkinson's disease (PD). Annovis Bio has two main compounds in clinical trials: ANVS401, currently in Phase 2a trials for early-stage AD and PD, as well as other chronic neurodegenerative conditions; and ANVS301, in Phase I trials to enhance cognitive function in advanced stages of AD. Additionally, the company is developing ANVS405 to protect the brain following traumatic brain injury or stroke.
Virion Therapeutics
Convertible Note in 2019
Virion Therapeutics, established in 2018 and based in Newark, Delaware, is a biotechnology company focused on developing immune-based treatments for virally-associated cancers and chronic viral infections. The company's primary products are ChiVax and ChiVax-gD vaccines, designed to induce potent and sustained T cell-mediated immune responses against transformed or infected cells. These vaccines have demonstrated promising results in pre-clinical testing and are poised for translation into clinical trials targeting diseases such as HPV-induced cancers and chronic Hepatitis B infections.
Immunome Inc., founded in 2006 and headquartered in Exton, Pennsylvania, is a biotechnology company focused on discovering, developing, and commercializing highly targeted and native human cancer antibodies against universal cancer antigens. The company utilizes its proprietary RealMAb technology to identify novel antigens and the corresponding native human antibodies that target them. Additionally, Immunome employs ScreenMab multiplex functional screening technology to pinpoint monoclonal antibodies with high specificity for tumor neoantigens.
KickUp, founded in 2014 and based in Philadelphia, Pennsylvania, operates a SaaS-based analytics platform designed specifically for K-12 school districts. The company helps professional development teams differentiate teacher support through data-driven insights, enabling them to align goals with district strategies, track real-time survey data, and coordinate learning efforts effectively. KickUp serves superintendents, directors of PD, and district leaders, empowering them to make informed decisions and demonstrate tangible classroom outcomes.
Intrommune Therapeutics
Series A in 2019
Intrommune Therapeutics is a clinical-stage biotechnology company focused on developing innovative treatments for food allergies. It aims to provide safe and effective options for individuals suffering from these conditions through its Oral Mucosal Immunotherapy (OMIT) platform. This platform utilizes a specially formulated toothpaste that integrates allergenic proteins into daily dental hygiene, allowing patients to retrain their immune systems while maintaining oral care. The company's lead product, INT301, targets peanut allergies, addressing a significant unmet need in a market where few effective treatments exist. Current options are limited and often involve risky procedures that deter patients from engaging. Intrommune's approach offers a promising alternative, enabling patients and their families to manage food allergies more effectively. The company is currently conducting a Phase 1b study for INT301, with key development milestones anticipated in the coming year.
Simply Good Jars
Seed Round in 2019
Simply Good Jars is a certified B-Corporation dedicated to promoting sustainability through its meal delivery service. The company operates smart refrigerated kiosks in offices, transit centers, universities, and healthcare facilities, offering chef-prepared, ready-to-eat meals packaged in reusable jars. These jars are designed to minimize waste, with a high return rate ensuring minimal environmental impact. For every jar returned, Simply Good Jars contributes to feeding someone in need, aligning its business model with social responsibility.
Ophidion
Venture Round in 2019
Ophidion is a biotechnology company focused on developing therapeutics for central nervous system disorders, particularly neurodegenerative diseases such as Alzheimer's, Parkinson's, and Huntington's disease. Utilizing a Trojan horse strategy, the company exploits an endogenous receptor-mediated transport system to deliver small molecule drugs and biologics directly into the brain. Ophidion specializes in gene-silencing therapies, including oligonucleotides and small interfering ribonucleic acids (siRNAs), which can be administered intravenously. In addition to its core focus on neurodegenerative diseases, Ophidion is advancing an innovative program aimed at treating anxiety-related disorders, which includes a patented companion biomarker diagnostic to optimize patient selection for treatment. The company's platform technology is versatile, capable of delivering various classes of drugs, including macromolecules like gene therapeutics, antibodies, and peptides, positioning Ophidion at the forefront of therapeutic advancements in CNS treatment.
WizeHive
Convertible Note in 2019
WizeHive, Inc. is a technology company that specializes in developing and operating cloud-based software platforms designed to help organizations streamline their business processes. Founded in 2009 and based in Conshohocken, Pennsylvania, WizeHive offers a range of software solutions including grants management, scholarship management, awards management, fellowship management, internship management, and accreditation management systems. These tools facilitate the collection, review, and organization of applications and records for various programs, catering to foundations, universities, and government agencies. WizeHive's flagship product, Zengine, is a user-friendly platform that enables non-technical users to build custom applications while allowing developers to enhance functionality through integrations and plugins. By automating administrative tasks and improving organizational efficiency, WizeHive helps its clients save time and resources.
Wash Cycle Laundry
Convertible Note in 2019
Wash Cycle Laundry Inc. is a laundry service provider based in Philadelphia, Pennsylvania, with an additional location in Washington, D.C. Founded in 2012, the company specializes in laundry, linen rental, and dry cleaning services for a diverse clientele, including universities, healthcare institutions, hotels, and individual customers. Wash Cycle Laundry is notable for its environmentally friendly practices, utilizing eco-friendly detergents and non-perc solvents in its cleaning processes. The company offers a range of services, including the washing of clothes, linens, towels, and janitorial supplies, as well as campus laundry plans and managed on-premise laundry services. Their commitment to sustainability and customer service is reflected in their unique bike-based pickup and delivery system, ensuring that clean laundry is returned promptly.
Burrow, Inc. is a New York-based company that designs, manufactures, and supplies luxury furniture for residential use. Founded in 2016, Burrow specializes in creating easy-to-move and customizable seating options such as sofas, sectionals, loveseats, and armchairs, as well as tables, rugs, and various accessories. The furniture is crafted from sustainably-sourced hardwood and features non-toxic, scratch- and stain-resistant fabrics. Burrow aims to provide customers with comfortable and stylish furnishing alternatives while avoiding traditional retail markups. The company operates showrooms in several states, including Washington, Massachusetts, Texas, and California, and also sells its products online. Additionally, Burrow has a manufacturing facility located in Mexico City, Mexico.
Sidecar Interactive, Inc. is an e-commerce technology company that specializes in providing software solutions for retailers to enhance their online marketing efforts. The company's primary offering is the Sidecar Predictive Bid Engine, which optimizes advertising bids for intelligent product groupings based on real-time data analysis. This system ensures that products receive appropriate bids to maximize visibility and return on advertising spend, while also allowing high-performing products to be managed individually. Additionally, Sidecar's solutions include dynamic product advertisements on social media platforms, enabling retailers to showcase their entire product catalogs effectively. By leveraging machine learning and extensive data analytics, Sidecar assists online retailers in managing their product listing advertisement campaigns, ultimately improving business performance and efficiency. Founded in 2007 and based in Philadelphia, Pennsylvania, Sidecar was previously known as Snipi, Inc. until its name change in 2011.
ExpressCells
Series A in 2019
ExpressCells, Inc. is a biotechnology company founded in 2018 and headquartered in Philadelphia, Pennsylvania. The company specializes in genetic engineering, focusing on the creation of custom knock-in cell lines tailored for drug discovery and biological research. ExpressCells employs advanced gene-editing technology to make precise modifications to a cell's genome, utilizing a patent-pending plasmid system to introduce new genes. This innovative approach enables researchers to visualize proteins and organelles within the cell, thereby enhancing their ability to model diseases and accelerate drug discovery processes.
Illumina Radiopharmaceuticals
Seed Round in 2019
Illumina Radiopharmaceuticals
Simply Good Jars
Pre Seed Round in 2018
Simply Good Jars is a certified B-Corporation dedicated to promoting sustainability through its meal delivery service. The company operates smart refrigerated kiosks in offices, transit centers, universities, and healthcare facilities, offering chef-prepared, ready-to-eat meals packaged in reusable jars. These jars are designed to minimize waste, with a high return rate ensuring minimal environmental impact. For every jar returned, Simply Good Jars contributes to feeding someone in need, aligning its business model with social responsibility.
LIA Diagnostics Inc. is a company based in Philadelphia, Pennsylvania, that specializes in developing innovative pregnancy test kits. Founded in 2015, the company focuses on addressing key issues associated with traditional pregnancy tests, specifically privacy, usability, and sustainability. LIA's test kits are made from eco-friendly materials, containing no plastic, and are designed to be foldable, flushable, and easy to carry. This design allows users to conduct tests discreetly and conveniently, while also minimizing confusion in test interpretation. By prioritizing sustainability and user experience, LIA Diagnostics aims to redefine the pregnancy testing process for women.
Virion Therapeutics
Series A in 2018
Virion Therapeutics, established in 2018 and based in Newark, Delaware, is a biotechnology company focused on developing immune-based treatments for virally-associated cancers and chronic viral infections. The company's primary products are ChiVax and ChiVax-gD vaccines, designed to induce potent and sustained T cell-mediated immune responses against transformed or infected cells. These vaccines have demonstrated promising results in pre-clinical testing and are poised for translation into clinical trials targeting diseases such as HPV-induced cancers and chronic Hepatitis B infections.
Proscia Inc., established in 2014 and headquartered in Philadelphia, Pennsylvania, specializes in digital pathology informatics through its innovative cloud-based platform. This platform aids in routine pathology operations, enhances cancer diagnosis, and seeks to improve patient outcomes. By leveraging advanced computing technologies, Proscia's solution unlocks hidden data that is not discernible to the human eye, transforming that information into valuable insights. These insights support physicians in accelerating the development of life-saving medical advances, ultimately contributing to a more effective diagnostic process in the field of pathology.
Burrow, Inc. is a New York-based company that designs, manufactures, and supplies luxury furniture for residential use. Founded in 2016, Burrow specializes in creating easy-to-move and customizable seating options such as sofas, sectionals, loveseats, and armchairs, as well as tables, rugs, and various accessories. The furniture is crafted from sustainably-sourced hardwood and features non-toxic, scratch- and stain-resistant fabrics. Burrow aims to provide customers with comfortable and stylish furnishing alternatives while avoiding traditional retail markups. The company operates showrooms in several states, including Washington, Massachusetts, Texas, and California, and also sells its products online. Additionally, Burrow has a manufacturing facility located in Mexico City, Mexico.