National Institutes of Health

The National Institutes of Health (NIH) is a leading biomedical research facility in the United States, operating under the Department of Health and Human Services. Established in 1887 and based in Bethesda, Maryland, NIH is the primary agency responsible for biomedical and health-related research in the country. It comprises 27 separate institutes and centers, each focusing on different disciplines within biomedical science. NIH conducts its own scientific research through the Intramural Research Program and provides significant funding for research at external institutions via the Extramural Research Program. With a workforce that includes 1,200 principal investigators and over 4,000 postdoctoral fellows, NIH has been instrumental in major medical breakthroughs, such as the development of vaccines for hepatitis and human papillomavirus, as well as the discovery of treatments for various health conditions. As the world's largest source of medical research funding, NIH continues to advance scientific knowledge and contribute to public health improvements.

Francis Collins

Director

Nick Langhals

Supervisory Program Director

971 past transactions

InVivo Biosystems

Grant in 2025
InVivo Biosystems develops and commercializes proprietary systems for genetic modification of non-mammalian model organisms like C. elegans and zebrafish. Their platform enables researchers worldwide to create custom models for aging, developmental, and disease studies, accelerating drug discovery and understanding human health.

Invizyne

Grant in 2025
Invizyne specializes in the design of enzymes and construction of cell-free enzymatic pathways for continuous, unassisted biomanufacturing outside living cells.

GreenMark Biomedical

Grant in 2025
GreenMark Biomedical Inc. is a minimally invasive healthcare company focused on developing innovative technologies utilizing biopolymer nanoparticles derived from natural starch. Founded in 2016 and based in East Lansing, Michigan, with a laboratory in Ann Arbor, the company specializes in dental and medical applications. Its dental technologies include a mouth rinse product that illuminates cavities and early-stage lesions, allowing dentists to accurately diagnose and treat tooth decay. Additionally, GreenMark's medical technologies are designed for targeted delivery of anti-cancer drugs, enhancing treatment precision. The company aims to provide health benefits through its advanced nanoparticle-based solutions, promoting less invasive and more effective healthcare practices.

SonoMotion

Grant in 2025
SonoMotion Inc. develops non-invasive medical devices for kidney stone disease, including Break Wave for fragmenting large stones and Stone Clear to remove fragments within about 15 minutes in office settings without general anesthesia or X-ray radiation. The company, founded in 2012 and based in San Mateo, California, focuses on office-based procedures that aim to simplify treatment, reduce hospital visits, and offer cost-efficient care for kidney stone patients.

LUCID DIAGNOSTICS

Grant in 2025
Lucid Diagnostics is a commercial-stage, cancer-prevention medical diagnostics company. Lucid focuses on patients with gastroesophageal disease (GERD), also known as chronic heartburn, who are at risk of developing esophageal precancer and cancer. Lucid’s EsoGuard Esophageal DNA Test is performed on samples collected in a brief noninvasive office procedure with its EsoCheck Esophageal Cell Collection Device, a diagnostic test capable of serving as a widespread screening tool to prevent cancer and cancer deaths through early detection of esophageal precancer in at-risk GERD patients.

Myosin Therapeutics

Seed Round in 2025
Myosin Therapeutics is a biopharmaceutical company focused on developing novel medications that target cellular motor proteins. It leverages molecular machines that convert energy into mechanical work inside cells to create therapies aimed at treating central nervous system disorders and other diseases, including cancer. The company concentrates on advancing pharmacotherapies that modulate motor protein activity to impact disease pathways and address significant unmet medical needs.

UCLA Health System

Grant in 2025
Comprised of Ronald Reagan UCLA Medical Center, UCLA Medical Center, Santa Monica; Resnick Neuropsychiatric Hospital at UCLA, Mattel Children's Hospital UCLA, and the UCLA Medical Group with its wide-reaching system of primary-care and specialty-care offices throughout the region, UCLA Health System is among the most comprehensive and advanced healthcare systems in the world.

Neuronoff

Grant in 2025
Neuronoff, a medical device company, is focused on the development of the Injectrode™, a novel injectable metal electrode, which is deployed via a small needle for manufacturing the neuromodulation interface inside the body on a variety of anatomical targets.

IVOS Medical

Grant in 2025
IVOS Medical is an innovative medical device company focused on advancing airway management technology.

Vast Therapeutics

Grant in 2025
Vast Therapeutics, Inc. is a preclinical-stage pharmaceutical company based in Durham, North Carolina, focused on developing inhalable treatments for antibiotic-resistant pathogens affecting patients with cystic fibrosis and other respiratory diseases. Established in 2017 and previously known as Novoclem Therapeutics, the company aims to address chronic infections that are prevalent in the cystic fibrosis population. Vast Therapeutics operates as a subsidiary of KNOW Bio, LLC, and is dedicated to advancing its innovative therapeutic solutions to improve health outcomes for patients facing these challenging conditions.

Arkansas Children's Research Institute

Grant in 2025
Arkansas Children's Research Institute is a not-for-profit organization affiliated with Arkansas Children's, Inc., and is dedicated to advancing pediatric health through research. It operates in conjunction with Arkansas Children's Hospital, the only pediatric medical center in Arkansas and one of the largest in the nation, which spans 29 city blocks and features 370 beds. The hospital employs around 500 physicians and more than 4,400 staff members, focusing on innovative medical research, surgical procedures, and intensive treatments aimed at improving children's health and development. The institute's research efforts contribute to the hospital's reputation for medical breakthroughs and have garnered recognition, including being ranked on the FORTUNE 100 Best Companies to Work For list for three consecutive years.

Feinstein Institute for Medical Research

Grant in 2025
Feinstein Institute For Medical Research is the research arm of Northwell Health, the largest health care provider and private employer in New York State. Home to 50 research labs, 3,000 clinical research studies and 5,000 researchers and staff, the Feinstein Institutes raises the standard of medical innovation through its five institutes of behavioral science, bioelectronic medicine, cancer, health innovations and outcomes, and molecular medicine. We make breakthroughs in genetics, oncology, brain research, mental health, autoimmunity, and are the global scientific leader in bioelectronic medicine – a new field of science that has the potential to revolutionize medicine.

Rhealth

Grant in 2025
Rhealth is a biotechnology company that develops AI-powered health management solutions for hospitals, offering a platform that delivers comprehensive health information to clinicians and patients and integrates portable diagnostics and monitoring capabilities to support timely, data-driven care.

University of Louisville

Grant in 2025
The University of Louisville is a public research university offering a range of undergraduate and graduate programs across various disciplines. It is committed to advancing knowledge through research in fields such as health, engineering, and the humanities. The university actively collaborates with community partners to enhance its academic and research initiatives, thereby contributing to the education, healthcare, and research sectors. Additionally, the University of Louisville School of Dentistry operates as a specialized institute within the university, focusing on dental education and practice.

University of Arkansas for Medical Sciences

Grant in 2025
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Scripps Health

Grant in 2024
Scripps Health is a private, nonprofit integrated health system based in San Diego, California. It is dedicated to delivering high-quality medical care and services to individuals and families, encompassing a range of healthcare needs from preventive services to specialized treatments. Scripps Health operates several top-ranked hospitals and provides access to some of the best medical professionals in the region. The organization emphasizes wellness screenings and comprehensive care at every stage of life, ensuring that community members receive the support they need for their health and well-being. Additionally, the Scripps Health Foundation plays a crucial role in facilitating philanthropic efforts that enhance the quality of patient care within the system.

Elimu Informatics

Grant in 2024
Elimu Informatics is a company that develops cloud-based clinical decision support software aimed at healthcare professionals. The firm focuses on enhancing the quality of patient care, improving patient experience, and ensuring usability through its expertise in clinical decision support, semantic normalization, and workflow integration. By providing these solutions, Elimu Informatics enables healthcare organizations to optimize their operations without the need for extensive development costs or lengthy implementation timelines.

BioCircuit Technologies

Grant in 2024
BioCircuit Technologies, Inc. is a medical device company based in Atlanta, Georgia, founded in 2016. The company specializes in developing noninvasive electrophysiology devices that monitor, control, and repair peripheral nerves. By utilizing multi-electrode arrays and proprietary algorithms, BioCircuit's products enable clinicians to diagnose health conditions more effectively, track the progression of symptoms over time, and select tailored treatments for individual patients. This innovative approach enhances the ability of healthcare providers to address nerve-related health issues with greater precision and efficiency.

BMI OrganBank

Grant in 2024
BMI OrganBank develops innovative medical devices and perfusion technology to enhance organ and tissue preservation for transplantation. The company collaborates with academic institutions to expand the possibilities of organ transplantation, aiming to improve patient outcomes.

Sparian Biosciences

Grant in 2024
Sparian Biosciences is an early-stage biopharmaceutical company dedicated to the discovery and development of innovative therapies for the central nervous system (CNS). The firm specializes in creating unique and transformative medicines that specifically target brain-related conditions. Sparian is committed to advancing therapeutic solutions that address both acute and chronic pain through cutting-edge science and novel drug discovery methods.

Emory University

Grant in 2024
Emory University is a public research university located in Atlanta, Georgia. It offers a range of undergraduate and graduate programs across various fields. The institution generates over $500 million in research funding annually while prioritizing teaching. Emory collaborates with local schools and partners to enhance its educational impact. The university's campus is in the historic Druid Hills area, and its connection to Atlanta shapes it. President James W. Wagner acknowledges the contributions of faculty, staff, students, and alumni to the university's mission and its commitment to improving what is considered good​.

Mount Sinai Health System

Grant in 2024
Mount Sinai Health System is an integrated healthcare system based in New York, providing exceptional medical care to local and global communities. Established in 2013 through the merger of Mount Sinai Medical Center and Continuum Health Partners, it encompasses the Icahn School of Medicine and operates seven hospital campuses throughout the New York metropolitan area. The system is recognized for its excellence in research, patient care, and education across various specialties. It features a vast network of over 7,000 primary and specialty care physicians, as well as more than 45 ambulatory practices and 12 minority-owned free-standing ambulatory surgery centers. Mount Sinai is committed to improving healthcare quality and accessibility, focusing on compassionate patient experiences and the development of strong relationships between staff and patients. Additionally, its venture capital arm, Mount Sinai Ventures, invests in healthcare startups, further enhancing its capacity to innovate and respond to the diverse health needs of the populations it serves.

ReShape Lifesciences

Grant in 2024
ReShape Lifesciences is a medical device company focused on technologies to treat obesity and metabolic diseases. The company develops and commercializes products designed to provide less invasive options for weight loss, including the Lap-Band System, an adjustable gastric banding device for long-term obesity management. It also has the ReShape Vest system, an investigational laparoscopically implanted device that wraps around the stomach and is designed to support weight loss without permanent changes to the GI tract; the Vest is primarily marketed outside the United States. The company traces its origins to EnteroMedics and adopted the ReShape Lifesciences name in 2017. It is headquartered in San Clemente, California, and operates in multiple international markets.

Novel Microdevices

Grant in 2024
Novel Microdevices, LLC is a medical device company that specializes in the development of handheld devices for molecular diagnostics. Founded in 2014 and headquartered in Annapolis, Maryland, the company has created the NOVEL DX device, which employs microfluidics technology to analyze raw biological samples at the point of care. This device delivers results in approximately 30 minutes, allowing healthcare professionals to achieve lab-quality diagnostics without the need for a traditional laboratory setting. Novel Microdevices caters to various sectors, including clinical diagnostics, biodefense, food safety, forensics, drug discovery, animal care, and agriculture, thus addressing a wide range of applications in health and safety.

Brixton Biosciences

Grant in 2024
Brixton Biosciences is a clinical-stage life sciences company developing therapies for pain management. The company focuses on non-addictive, locally targeted treatments delivered via a drug-free injectable that produces reversible nerve inhibition, aiming to provide long-lasting relief. Its lead approach seeks to extend pain relief from a single injection to thirty to sixty days, reducing reliance on systemic medications and addressing unmet needs in both chronic and acute pain.

YoungHeartValve

Grant in 2024
Young Heart Valve is a Polymeric, Hyaluronan-Enhanced Transcatheter Aortic Valves which were developed by engineers with inspiration from nature. The future of heart valve intervention is being altered by Young Heart Valve. Animal tissue is no longer required thanks to Young Heart Valve. Hyaluronan is included into the leaflets of Young Heart Valve's RejuvenateTM TAVR device, forming a biomolecular interpenetrated network that has been shown to be resistant to calcification and thrombosis.

ATCC

Grant in 2024
ATCC global biological materials resource and standards organization whose mission focuses on the acquisition, authentication, production, preservation, development, and distribution of standard reference microorganisms, cell lines, and other materials. While maintaining traditional collection materials, ATCC develops high-quality products, standards, and services to support scientific research and breakthroughs that improve the health of global populations.

CareTaker Medical

Grant in 2024
CareTaker Medical develops wireless patient monitoring devices. Its flagship product, CareTaker, is a wearable system that measures continuous beat-by-beat blood pressure, heart rate, respiration rate, and other hemodynamic parameters using only a finger cuff. The device securely transmits data over cellular networks or Bluetooth to enable remote patient monitoring within hospitals and during transport.

Pip Care

Grant in 2024
Pip Care is a healthcare company offering a personalized surgical journey platform that digitizes and automates perioperative processes for health systems. The platform supports care teams from preparation to recovery, with a perioperative care app to help patients prepare for and recover from surgery. The company also provides certified health coaches who develop personalized recovery plans with daily tasks and curated advice, enabling patients to track appointments and stay prepared. By aligning care teams and patient steps, Pip Care aims to improve surgical outcomes and efficiency for health systems.

Arkansas Children's Research Institute

Grant in 2024
Arkansas Children's Research Institute is a not-for-profit organization affiliated with Arkansas Children's, Inc., and is dedicated to advancing pediatric health through research. It operates in conjunction with Arkansas Children's Hospital, the only pediatric medical center in Arkansas and one of the largest in the nation, which spans 29 city blocks and features 370 beds. The hospital employs around 500 physicians and more than 4,400 staff members, focusing on innovative medical research, surgical procedures, and intensive treatments aimed at improving children's health and development. The institute's research efforts contribute to the hospital's reputation for medical breakthroughs and have garnered recognition, including being ranked on the FORTUNE 100 Best Companies to Work For list for three consecutive years.

Teal Health

Grant in 2024
Teal Health specializes in developing at-home cervical cancer screening devices, aiming to enhance convenience, privacy, and accessibility for women. Their FDA-approved platform includes a sampling device, virtual consultations with licensed providers, secure laboratory testing, an online results portal, and coordination of follow-up care.

Allyx Therapeutics

Grant in 2024
Allyx Therapeutics, Inc. is a clinical-stage biotechnology company founded in 2018 and based in Durham, Connecticut. The company specializes in developing disease-modifying treatments for Alzheimer's Disease, with a focus on reversing neurodegeneration. Its lead product is an orally bioavailable small molecule that functions as a silent allosteric modulator of mGluR5. This innovative approach aims to provide clinicians with a therapeutic option capable of preserving cognition in patients while addressing the underlying disease mechanisms.

CardieX

Grant in 2024
CardieX is a global health technology company focused on cardiovascular health management, including hypertension and vascular disorders. It designs, manufactures, and markets medical devices and digital health tools that measure cardiovascular risk, monitor arterial stiffness and central blood pressure, and support patient management across hospitals, clinics, research institutions, and pharmaceutical companies in the Americas, Europe, and the Asia-Pacific region. The company offers TeleHealth services with digital, e-commerce, and mobile tools enabling online connections with health coaches. Its products include devices based on patented arterial stiffness and central blood pressure technologies, and wearables with health analytics. CardieX collaborates with external partners to develop wearable sensors and hypertension programs. The company traces its origins to AtCor Medical and rebranded to CardieX in 2018. CardieX was founded in 1994 and is headquartered in Sydney, Australia.

University of Michigan

Grant in 2024
The University of Michigan, one of the largest universities in the Midwest, offers a diverse array of academic programs that attract over 40,000 undergraduate, graduate, and professional students. Its renowned schools include the Stephen Ross School of Business, the College of Engineering, and prominent law and medical schools. The university also has a vibrant arts scene, highlighted by its Musical Theatre program and the annual Ann Arbor Film Festival, which draws filmmakers globally. In addition to its educational endeavors, the University of Michigan actively manages a significant endowment, investing in alternative assets such as private equity, real estate, and infrastructure to support its mission and enhance its resources. The institution consistently ranks highly in national assessments, reflecting its commitment to academic excellence and innovation.

Southern California University of Health Sciences

Grant in 2024
Southern California University of Health Sciences has been a leader in educating students to be competent and caring integrative healthcare practitioners for over 100 years. SCU has a history of providing the highest levels of patient care and has gained a reputation for excellence in an evidenceinformed curriculum. SCU is the best place to prepare for a successful, significant, and rewarding career.

Instituto Nacional de Salud Publica

Grant in 2024
The Instituto Nacional de Salud Publica is an academic institution whose central commitment to Mexican society is to provide research results to relevant public health problems in order to prevent and control diseases, as well as to train health professionals who help promote healthy living conditions in the community's various groups. population.

Rosalind Franklin University of Medicine and Science

Grant in 2024
Rosalind Franklin University of Medicine and Science, established in 1912, is a North Chicago, Illinois-based institution dedicated to educating future health science leaders. It comprises five schools offering degrees such as Doctor of Medicine, Doctor of Podiatric Medicine, Nurse Anesthesia, Physical Therapy, and Physician's Assistant. The university fosters research and provides opportunities for students to engage in it, both on campus and through partnerships with nearby institutions. It aims to enrich students' lives professionally, mentally, and socially through various organizations and activities. Admission requirements vary by school but generally seek students with a strong scientific background and leadership skills. The university offers financial aid to eligible students who demonstrate need.

Oklahoma Medical Research Foundation

Grant in 2024
The Oklahoma Medical Research Foundation (OMRF) is a non-profit biomedical research institute dedicated to understanding and treating various devastating illnesses, including Alzheimer's, heart disease, lupus, multiple sclerosis, and cancer. It operates a research facility, providing services and access to resources that facilitate drug discoveries and improve patient care.

CytoAgents

Grant in 2024
CytoAgents is a clinical-stage biotechnology company focused on developing innovative pharmaceutical products for treating life-threatening symptoms associated with Cytokine Release Syndrome (CRS), an overreaction of the immune system causing systemic inflammation.

Amissa Health

Grant in 2024
Amissa develops mobile and wearable application solutions aimed at alleviating the challenges of Alzheimer's care. The company’s technology empowers caregivers by allowing them to geo-fence and locate loved ones who may wander, remotely monitor their activity and health, and predict behaviors associated with Alzheimer's. In addition to these features, Amissa offers wearable biosensors integrated with a cloud-based data platform that collects biometric data on activity levels, sleep patterns, and physiological changes. This comprehensive approach not only aids caregivers in monitoring patients but also provides valuable insights for researchers seeking to understand disease progression, ultimately enhancing the quality of life for individuals with dementia and related disorders.

Resvita Bio

Grant in 2024
Resvita Bio develops and manufactures engineered probiotics for treating skin-related diseases, including cancer. Leveraging a synthetic biology platform, the company uses genetically engineered bacteria to produce and deliver therapeutic proteins directly to affected skin areas, providing continuous treatment and addressing limitations of traditional therapies. It targets conditions such as Netherton Syndrome and Severe Atopic Dermatitis, pursuing novel methods to manage skin disorders through localized, sustained protein delivery.

Cenna Biosciences

Grant in 2024
Cenna Biosciences is a biosciences company focused on the discovery and development of innovative drugs aimed at preventing and treating Alzheimer's disease. The company employs a proprietary mechanism to address the underlying cause of the disease, specifically targeting the inappropriate deposition of toxic ß-amyloid species in the brains of affected patients. Cenna Biosciences has identified a novel target and is actively developing several lead peptide compounds as disease-modifying candidates for Alzheimer's treatment.

Lasarrus

Grant in 2024
Lasarrus is a medical device company founded in 2013 and headquartered in Baltimore, Maryland. The company specializes in developing wearable devices aimed at enhancing the physical therapy experience for patients, particularly those with chronic obstructive pulmonary disease. Lasarrus's innovative device facilitates remote monitoring and telemedicine by capturing physiological and range-of-motion data from various points on the body. This technology provides patients with an affordable, comfortable, and non-invasive means to track their health routines and accelerate their recovery process.

Tiziana Life Sciences

Grant in 2024
Tiziana Life Sciences is a UK-based clinical-stage biotechnology company focused on discovering and developing novel molecules to treat diseases in oncology and immunology. Its pipeline includes Foralumab for autoimmune and inflammatory diseases, Milciclib for hepatocellular carcinoma, Anti IL-6r for severe COVID-19 symptoms, and StemPrintER for breast cancer diagnosis.

Nasoni

Grant in 2024
Founded in 2015, Nasoni designs and manufactures innovative fountain faucets, offering a range of styles including centerset and widespread options in polished chrome, brushed nickel, and black nickel finishes. The company also develops intelligent health technology that transforms daily routines into wellness opportunities for aging-in-place, using ambient mmWave radar and AI to monitor self-care behaviors without cameras or wearables.

TransCode Therapeutics

Grant in 2024
TransCode Therapeutics, founded in 2016 and based in Boston, Massachusetts, is a biopharmaceutical company dedicated to discovering, developing, and commercializing innovative RNA therapeutics for treating metastatic cancer. Its lead therapeutic candidate targets an RNA molecule that drives metastatic disease across multiple tumor types.

Subtle Medical

Grant in 2024
Subtle Medical is a healthcare technology company that develops artificial‑intelligence software for magnetic resonance and positron emission tomography imaging. Its flagship products, SubtleMR and SubtlePET, are FDA‑cleared and CE‑marked tools that enhance image quality by reducing noise and sharpening detail, allowing scans to be performed faster and with lower radiation or contrast dose. The company’s deep‑learning algorithms integrate with any scanner without changing existing workflows, enabling imaging centers and hospitals to increase throughput and improve patient safety. Subtle Medical also offers a vendor‑agnostic AI platform that delivers analytics and support to clinical imaging providers. Founded in 2017 and headquartered in Menlo Park, California, the firm has received an NIH SBIR grant and an RSNA award for its GAD technology.

Precision Epigenomics

Grant in 2024
Precision Epigenomics, established in 2020 and based in Tucson, Arizona, specializes in molecular diagnostics for cancer. The company focuses on developing innovative molecular diagnostic assays, leveraging DNA methylation analysis, an epigenetic modification, to enhance cancer diagnosis and treatment. Their offerings aim to address unmet clinical needs, aiding clinicians in improved patient management.

Evoq Therapeutics

Grant in 2024
Evoq Therapeutics is a biotechnology company that develops immunotherapies intended to restore immune tolerance in autoimmune diseases. Its proprietary nanodisc platform delivers disease-specific antigens to modulate immune responses, with NanoDisc constructs designed to train the immune system to tolerate targeted proteins while preserving overall immunity. The approach has shown activity in preclinical models of autoimmune conditions including celiac disease, type 1 diabetes, lupus, pemphigus, Graves’ disease, and rheumatoid arthritis, among others. Through these nanodisc-based therapies, Evoq Therapeutics aims to provide treatment options that reduce pathological immune activity and improve patient outcomes without broad immunosuppression.

Ensysce Biosciences

Grant in 2024
Ensysce Biosciences is a clinical-stage biotechnology company developing safer prescription drugs using proprietary platforms. It focuses on creating abuse-resistant opioids and overdose-protection products to reduce addiction risks and accidental overdoses associated with traditional opioids.

Unlocked Labs

Grant in 2024
Unlocked Labs develops targeted probiotics designed to manage specific health conditions. Their first product focuses on reducing kidney stone risk by digesting a stone-forming compound found in healthy foods like leafy vegetables.

Penderia Technologies

Grant in 2024
Penderia Technologies is a medical device company focused on innovative orthopedic solutions. It develops implantable, battery-less sensors for monitoring injury and healing progress in real-time, enabling personalized rehabilitation therapies.

Marker Therapeutics

Grant in 2024
Marker Therapeutics is a clinical-stage immuno-oncology company developing adoptive non-gene modified T cell therapies for treating hematologic malignancies. Its MultiTAA technology selectively expands non-engineered T cells to target and kill tumor cells expressing multiple tumor-associated antigens, preventing immune escape.

University of Arkansas for Medical Sciences

Grant in 2024
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Immunovia

Grant in 2024
Immunovia is a diagnostics company focused on the early detection of pancreatic cancer and other complex diseases. It develops and commercializes innovative diagnostic tools using its proprietary technology platform, IMMray, which is based on antibody microarray analysis. The company conducts clinical trials and validation studies to ensure the accuracy and reliability of its tests. By collaborating with medical institutions and research centers worldwide, Immunovia aims to bring its diagnostic solutions to market, significantly impacting the treatment and management of pancreatic cancer and potentially improving survival rates. Its approach to utilizing blood-based biomarkers may also enable early detection strategies for other cancers and autoimmune diseases.

Cortechs.ai

Grant in 2024
Cortechs.ai is a developer of brain image analysis software that enhances clinical insight through quantitative imaging. The company's innovative solutions are utilized by neurologists and radiologists in numerous clinics and research centers globally. Its software provides a practical and cost-effective approach to quantifying brain structures, aiding medical professionals in the evaluation of various neurological conditions, including Alzheimer's disease, multiple sclerosis, epilepsy, and traumatic brain injury. Through its advanced imaging technology, Cortechs.ai aims to improve diagnostic accuracy and treatment outcomes in the field of neurology.

MaMome

Grant in 2024
MaMome is dedicated to advancing women's health, beginning with pregnancy, and extending beyond, by utilizing microbiome coupled with machine learning/AI, we precisely identify expectant mothers at elevated risk of pregnancy complications.

Anebulo Pharmaceuticals

Grant in 2024
Anebulo Pharmaceuticals is a clinical-stage biotechnology company focused on developing therapies for cannabinoid overdose and substance addiction. Its lead candidate, ANEB-001, is designed to reverse the effects of cannabinoid overdose within about one hour of administration. Early clinical data indicate rapid absorption and tolerability, with weight loss observed potentially linked to central cannabinoid receptor type 1 antagonism. The company aims to address acute overdose symptoms such as sedation, anxiety, panic, and psychosis by restoring balance to the endocannabinoid system.

Arkansas Children's Research Institute

Grant in 2024
Arkansas Children's Research Institute is a not-for-profit organization affiliated with Arkansas Children's, Inc., and is dedicated to advancing pediatric health through research. It operates in conjunction with Arkansas Children's Hospital, the only pediatric medical center in Arkansas and one of the largest in the nation, which spans 29 city blocks and features 370 beds. The hospital employs around 500 physicians and more than 4,400 staff members, focusing on innovative medical research, surgical procedures, and intensive treatments aimed at improving children's health and development. The institute's research efforts contribute to the hospital's reputation for medical breakthroughs and have garnered recognition, including being ranked on the FORTUNE 100 Best Companies to Work For list for three consecutive years.

Weill Cornell Medicine

Grant in 2024
Weill Cornell Medicine is a renowned academic medical center dedicated to excellence in patient care, scientific discovery, and educating future physicians. With over 300 IT professionals supporting more than 10,000 users across its institutions, it offers comprehensive technology services, including infrastructure management, security, networking, software development, and innovative solutions for clinical and research projects.

VenoStent

Grant in 2024
VenoStent develops bioabsorbable smart polymer wraps for vascular surgeries. Its flagship product, SelfWrap, is a perivascular wrap designed to reduce failures at the vein-artery junction in dialysis patients by promoting outward vein growth and providing custom-fit mechanical support. The company's technology acts as an external stent, reducing surgery time, infection risk, and wound reopening while improving vein usability and durability.

Metabolon

Grant in 2024
Metabolon develops metabolomics-based platforms and clinical diagnostic tests for early disease detection and precision medicine. It offers blood tests like QUANTOSE IR and QUANTOSE IGT, and Meta IMD for inherited metabolic disorders. The company serves various sectors including academia, biotech/pharmaceuticals, and precision medicine. It has strategic partnerships with major pharmaceutical companies and other industries.

CUNY Graduate School of Public Health and Health Policy(CUNY SPH)

Grant in 2024
CUNY SPH promotes and sustains healthier populations in their city and around the world through education, research, and service in public health. They offer essential insights into public health problems and solutions. They believe collaboration leads to innovative and impactful research, programs, and policies.

Preeclampsia Foundation

Grant in 2024
Preeclampsia Foundation is a nonprofit that focuses on reducing maternal and infant illness and death due to preeclampsia.

Ensysce Biosciences

Grant in 2024
Ensysce Biosciences is a clinical-stage biotechnology company developing safer prescription drugs using proprietary platforms. It focuses on creating abuse-resistant opioids and overdose-protection products to reduce addiction risks and accidental overdoses associated with traditional opioids.

Matter Bio

Grant in 2024
Matter Bio is a biotechnology company dedicated to preserving genomic integrity. It offers research services aimed at enhancing longevity by safeguarding and utilising DNA information. The company's primary focus is assembling an elite team of scientists and executives to combat genetic mutations and extend patient lifespan through innovative approaches to reverse such mutations.

Nanopath

Grant in 2024
Nanopath is a molecular diagnostics company that develops innovative platforms for rapid disease diagnosis. Its technology enables point-of-care testing, eliminating the need for nucleic acid amplification and supporting multiplexed detection. This allows patients and healthcare providers to access accurate diagnostic results within standard office visits, improving healthcare outcomes.

Phenomix Sciences

Grant in 2024
Founded in 2017, Phenomix Sciences is a biotechnology company specializing in metabolomics and genomics. It develops precision medicine tools for chronic disease management, focusing on obesity. The company's AI-driven platform offers a novel blood test to classify patients' unique pathophysiological phenotypes, enabling personalized treatment with improved efficacy and fewer side effects.

Arkansas Children's Research Institute

Grant in 2024
Arkansas Children's Research Institute is a not-for-profit organization affiliated with Arkansas Children's, Inc., and is dedicated to advancing pediatric health through research. It operates in conjunction with Arkansas Children's Hospital, the only pediatric medical center in Arkansas and one of the largest in the nation, which spans 29 city blocks and features 370 beds. The hospital employs around 500 physicians and more than 4,400 staff members, focusing on innovative medical research, surgical procedures, and intensive treatments aimed at improving children's health and development. The institute's research efforts contribute to the hospital's reputation for medical breakthroughs and have garnered recognition, including being ranked on the FORTUNE 100 Best Companies to Work For list for three consecutive years.

Annoviant

Grant in 2024
Annoviant is a healthcare company focused on the development of innovative medical devices, specifically tissue-based valve and conduit replacement systems. These devices are designed to address congenital deficiencies by replacing or patching structures that are either absent or underdeveloped. Annoviant's products are characterized by their regenerative capabilities, as well as their resistance to thrombosis, calcification, and infection. By maintaining essential mechanical properties, these devices empower clinicians to enhance clinical outcomes for substitute conduit arteries in infants and children, significantly reducing the likelihood of repeat surgeries.

University of California San Diego

Grant in 2024
The University of California San Diego (UC San Diego) is a public research university renowned for its diverse undergraduate and graduate programs across multiple disciplines. It emphasizes research, community engagement, and interdisciplinary collaboration, making it a hub for innovation and education. The university houses the School of Medicine, which prepares students for careers in healthcare by equipping them with the necessary knowledge and skills to become dedicated medical professionals. Additionally, UC San Diego fosters a multidisciplinary approach to complex systems through its human-centered design thinking labs, collaborating with various industrial partners in fields such as automation and healthcare. It actively supports student involvement in leadership and offers resources for studying abroad, enhancing the overall educational experience.

University of Arkansas for Medical Sciences

Grant in 2024
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Selsym Biotech

Grant in 2024
Selsym Biotech is a biotechnology company developing platelet-mimetic therapies and hemostatic technologies to control bleeding in trauma, surgery, and wound care. The company’s approach combines biomimetic platelet-inspired mechanisms with innovative materials such as Hemostatic Healing Hydrogels (H3) to promote rapid hemostasis and tissue repair. By addressing ongoing platelet supply shortages and shelf life challenges, Selsym Biotech aims to provide readily available, effective bleeding management solutions for emergency and surgical settings. The firm focuses on enabling healthcare providers to manage hemorrhage more effectively, reduce transfusion needs, and improve patient outcomes through therapies that mimic native platelet function and enhance wound healing.

The Feinstein Institutes

Grant in 2024
The Feinstein Institutes is a research services centre.

Cincinnati Children’s

Grant in 2024
Cincinnati Children’s Hospital Medical Center is a leading institution dedicated to improving child health, attracting patients and families both regionally and internationally. Recognized for its expertise, the hospital serves as a referral center for complex surgical procedures and treatments for rare pediatric diseases. The center is committed to advancing pediatric medicine by discovering innovative and effective treatment methods, solidifying its reputation as one of the foremost facilities for pediatric care globally.

Lamassu Pharma

Grant in 2024
Lamassu Pharma is a biotech startup developing small-molecule therapies for severe acute pancreatitis, with a lead candidate developed at Mayo Clinic that has shown strong preclinical results in reducing mortality and morbidity. The company is advancing this compound through safety testing in preparation for definitive clinical trials, aiming to deliver life-saving treatments to patients. In addition, Lamassu develops other small-molecule therapeutics targeting urgent medical needs, including potential cancer treatments, pursuing multiple candidates through clinical development. The organization emphasizes a patient-centric, evidence-based research approach to accelerate translation of science into therapies for unmet medical needs.

Springbok Analytics

Grant in 2024
Springbok Analytics offers an AI-powered software platform that transforms MRIs into three-dimensional analyses of muscle to enable true precision. Springbok Analytics' advanced imaging technology identifies and measures each individual muscle, providing data to scientists, physical therapists, athletic trainers, and physicians to evaluate muscle function in relation to performance and injury management. The technology has numerous applications, including injury management, performance enhancement, and the treatment of musculoskeletal conditions.

Phase

Grant in 2024
Phase provides 3D-printing medical devices for microfluidics. Phase’s proprietary platform enables PDMS (Sylgard 184) to be 3D printed at a scale and resolution that was previously unattainable.

Behaivior

Grant in 2024
Behaivior LLC is a digital health company based in Pittsburgh, Pennsylvania, focused on predicting and preventing addiction relapses through innovative technology. Founded in 2017, Behaivior integrates wearable devices with machine learning algorithms to analyze real-time data from various physiological metrics, such as heart rate and skin temperature. The company’s platform, known as Recovery, employs this data to deliver timely interventions tailored to the needs of individuals in recovery. By utilizing a SaaS business model, Behaivior aims to democratize mental health recovery and support, assisting users in maintaining their wellness while enabling care providers to enhance their service delivery. Through its proactive approach, Behaivior seeks to improve mental health outcomes and reduce crisis events associated with addiction.

Maxim Biotech

Grant in 2024
Maxim Biotech provides vitro diagnostic testing development and testing solutions.

BetterAge

Grant in 2024
BetterAge is a company dedicated to enhancing the health and well-being of older adults through innovative technology solutions. Founded on the principle that all adults can age well regardless of their current circumstances, BetterAge has developed a digital platform designed exclusively for this demographic. The platform provides personalized, objective content tailored to the needs of older adults, offering education and information about disease risks and actionable insights to support informed decision-making. By fostering a network of experts in aging services, health, and technology, BetterAge aims to create thriving communities where older adults can lead active and healthy lives.

Perspective Therapeutics

Grant in 2024
Perspective Therapeutics specializes in developing radiopharmaceuticals for targeted cancer treatment. Utilizing its proprietary technology centered around the alpha-emitting isotope Lead-212, the company aims to deliver precise radiation therapy directly to cancer cells.

AcuraStem

Grant in 2024
AcuraStem is a biotechnology company based in Monrovia, California, founded in 2016. The company specializes in developing a precision medicine platform that utilizes complex cellular models derived from Amyotrophic Lateral Sclerosis (ALS) patients' cells. AcuraStem employs advanced cellular reprogramming and artificial intelligence technologies to create patient-specific treatments for neurodegenerative diseases. Their platform is designed to evaluate disease progression and test existing therapeutics, as well as combinations of therapeutic approaches, to identify effective treatments that could slow disease progression. The company's team includes PhDs, professors, tech entrepreneurs, and veterans from the drug industry, all working towards addressing the challenges posed by ALS.

University of Arkansas for Medical Sciences

Grant in 2024
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

InVivo Biosystems

Grant in 2024
InVivo Biosystems develops and commercializes proprietary systems for genetic modification of non-mammalian model organisms like C. elegans and zebrafish. Their platform enables researchers worldwide to create custom models for aging, developmental, and disease studies, accelerating drug discovery and understanding human health.

RNAConnect

Grant in 2024
RNAConnect specializes in developing enzymatic tools for visualizing and manipulating RNA, with a focus on low-abundance and long, structured RNAs. Their core product is a reverse transcriptase designed to provide greater visibility into these challenging RNA types and their various isoforms. This enzyme is optimized to synthesize cDNA with high fidelity and processivity, enabling researchers to study complex RNA template structures without the need for heat.

Midwest Bioprocessing Center

Grant in 2023
Midwest Bioprocessing Center is a pioneer in glycochemical bioprocess technology.

University of Arkansas for Medical Sciences

Grant in 2023
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Orlance

Grant in 2023
Orlance provides more effective therapeutic and preventive vaccines for a wide spectrum of viral targets.

Amydis

Grant in 2023
Amydis is a privately-held pharmaceutical company dedicated to developing innovative diagnostic tools for detecting diseases linked to amyloid protein deposits. Its core technology involves novel compounds that fluoresce upon binding to amyloid proteins, enabling non-invasive diagnosis. Amydis' primary focus is on early-stage Alzheimer's disease detection, with other potential applications including Parkinson's disease, Creutzfeldt-Jakob disease, and various forms of amyloidosis. The company aims to provide faster, more accessible, and affordable diagnostic solutions compared to existing methods, contributing to better healthcare decisions for patients and their families.

Virtuoso Surgical

Grant in 2023
Virtuoso Surgical develops endoscopic robotic tools for minimally invasive surgery. Its Virtuoso robotic surgery system enables surgeons to overcome limitations of traditional endoscopes, with needle-sized robotic arms that reach difficult-to-access areas. The company focuses on simplifying endoscopic procedures and provides a range of tools to help surgeons perform operations more effectively and potentially improve patient outcomes.

The Stark Neurosciences Research Institute

Grant in 2023
The Stark Neurosciences Research Institute is dedicated to improving outcomes for persons suffering from disorders of the nervous system.

Hillhurst Biopharmaceuticals

Grant in 2023
Hillhurst Biopharmaceuticals specializes in developing innovative, liquid therapeutic gases for treating sickle cell disease. Their core technology enables the oral delivery of low-dose carbon monoxide, targeting the protective heme oxygenase system to reduce inflammation, prevent cell death, and halt hemoglobin polymerization. This approach addresses challenges associated with traditional inhaled gas therapies, such as caregiver exposure and imprecise dosing, ensuring accurate and safe administration.

Endomimetics

Grant in 2023
Endomimetics develops bio-nanometric coating technology for stents, aiming to enhance care for patients with kidney disease. Its innovative coating mimics human tissue, reducing complications and surgeries associated with implanted devices.

New York Society for the Prevention of Cruelty to Children

Grant in 2023
Founded in 1875, this organization provides counseling, legal aid, and educational resources to protect and support children in need across New York City.

Soterya

Seed Round in 2023
On average, we spend a third of our lives in bed. Our self-positioning bed; the Korus™, combined with our AI-driven software, is designed to provide precise sleep therapies improving lifestyle and medical care that benefits sleep wellness and faster recovery at home.

Rivanna

Grant in 2023
Rivanna Medical, LLC is a medical technology company founded in 2010 and headquartered in Charlottesville, Virginia. The company specializes in the development and commercialization of Accuro, an advanced ultrasound-based system designed to enhance the application of spinal and epidural anesthesia through automated three-dimensional navigation of the lumbar spine. In addition to its primary focus on anesthesia, Rivanna Medical's technology also encompasses various imaging applications, including diagnostic imaging for musculoskeletal and abdominal anatomies. By leveraging innovative ultrasound technology, Rivanna Medical aims to lower healthcare costs, improve patient outcomes, and minimize the risks associated with radiation from traditional X-ray-based imaging.

Center for HIV Identification, Prevention, and Treatment Services

Grant in 2023
Center for HIV Identification, Prevention, and Treatment Services is a research organisation that conducts HIV research. They offers customer support through email and phone contact.
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