Ligand Pharmaceuticals

Ligand Pharmaceuticals is a biopharmaceutical company that specializes in developing and acquiring technologies aimed at enhancing the drug discovery and development process. The company operates through partnerships and license agreements with various pharmaceutical and biotechnology firms, leveraging its strengths in drug discovery, early-stage development, and product reformulation. Ligand generates revenue through three primary channels: royalties from commercialized products, license and milestone payments, and the sale of its proprietary Captisol material. By maintaining a diversified portfolio of revenue streams and a low corporate cost structure, Ligand offers investors a lower-risk opportunity within the biotech sector.

Todd Davis

CEO and Board Member

Past deals in Pennsylvania

Castle Creek Biosciences

Venture Round in 2025
Castle Creek Biosciences, Inc. is a gene therapy company headquartered in Exton, Pennsylvania, that specializes in developing and commercializing personalized gene therapies for rare skin and connective tissue disorders. Founded in 2015, the company utilizes a fibroblast technology platform that extracts fibroblast cells from a patient's own skin to create localized therapies tailored to the individual’s unique biology. This innovative approach aims to address the underlying causes of diseases that currently have high unmet medical needs, ultimately improving the lives of patients suffering from these underserved conditions.

Palvella Therapeutics

Post in 2024
Palvella Therapeutics, based in Wayne, Pennsylvania, is a clinical-stage biopharmaceutical company established in 2015. It focuses on developing and commercializing targeted therapies for serious and rare genetic skin diseases, specifically genodermatoses. The company's lead product, QTORIN, is a specialized anhydrous gel designed to deliver active ingredients effectively into the skin, addressing the underlying causes of various dermatological conditions. Palvella's pipeline includes candidates aimed at treating microcystic lymphatic malformations and cutaneous venous malformations, utilizing its proprietary QTORIN platform to offer innovative solutions for underserved patient populations.

Palvella Therapeutics

Series C in 2020
Palvella Therapeutics, based in Wayne, Pennsylvania, is a clinical-stage biopharmaceutical company established in 2015. It focuses on developing and commercializing targeted therapies for serious and rare genetic skin diseases, specifically genodermatoses. The company's lead product, QTORIN, is a specialized anhydrous gel designed to deliver active ingredients effectively into the skin, addressing the underlying causes of various dermatological conditions. Palvella's pipeline includes candidates aimed at treating microcystic lymphatic malformations and cutaneous venous malformations, utilizing its proprietary QTORIN platform to offer innovative solutions for underserved patient populations.

Palvella Therapeutics

Corporate Round in 2018
Palvella Therapeutics, based in Wayne, Pennsylvania, is a clinical-stage biopharmaceutical company established in 2015. It focuses on developing and commercializing targeted therapies for serious and rare genetic skin diseases, specifically genodermatoses. The company's lead product, QTORIN, is a specialized anhydrous gel designed to deliver active ingredients effectively into the skin, addressing the underlying causes of various dermatological conditions. Palvella's pipeline includes candidates aimed at treating microcystic lymphatic malformations and cutaneous venous malformations, utilizing its proprietary QTORIN platform to offer innovative solutions for underserved patient populations.
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