Reinforced Ventures

Enigma Aerospace specializes in developing autonomous aerial logistics technologies for defense and B2B markets. The company aims to revolutionize logistics by advancing drone technologies, targeting significant opportunities in global logistics and air cargo sectors. Its focus includes enhancing efficiency in package delivery and related logistics services.

Solideon develops wire arc additive manufacturing WAAM solutions for large metallic components, enabling multi-robot, multi-tool manufacturing cells that produce finished parts in days rather than months. The company focuses on aerospace vehicle manufacturing and related infrastructure applications, leveraging additive manufacturing systems and machine-learning collaboration to build vehicles and infrastructure on Earth, the Moon, and Mars. This approach aims to expand space research capabilities and accelerate transportation and infrastructure projects, creating new opportunities across industries. Solideon emphasizes rapid production, scalable automation, and data-driven optimization to streamline fabrication of high-strength components for aerospace and other high-demand sectors.

Biophysical Therapeutics is a biotechnology company focused on designing new drugs using computational biology. The firm has developed a pipeline of experimentally validated drug candidates targeting cancer, diseases of aging such as Alzheimer's disease, and the broader concept of aging itself. In addition to its pharmaceutical endeavors, the company is also exploring opportunities in cosmetics. Biophysical Therapeutics has a history of contributing to fundamental biology and holds a portfolio of granted patents for both preclinical and repurposed clinical-stage drugs. The company is actively pursuing longevity drug candidates aimed at slowing, halting, or reversing the aging process. Founded by Dr. Michael Forrest, a biochemistry graduate from Cambridge University with a Ph.D. in computer science, the company benefits from the advisory expertise of Professor George Church from Harvard Medical School.

Founded in 2018, Ottometric develops a cloud-based platform that enhances safety for autonomous vehicles. It uses AI, sensor fusion, and computer vision to analyze real-world scenarios, providing deeper insights into system effectiveness and anomalies.

Wayfinder Biosciences is a biotechnology company focused on developing orally available small molecule drugs that modulate RNA targets linked to cancer and neurodegenerative diseases. The company uses a proprietary platform that combines high-throughput screening, computational modeling, and machine learning with unique datasets to discover RNA-targeting compounds with potency and selectivity for traditionally inaccessible targets. Its approach includes RNA biosensor technologies that render target molecules detectable, aiding discovery and evaluation. Founded in 2021 and based in Seattle, Wayfinder aims to accelerate development of therapies for undruggable targets by enabling rapid screening and optimization of RNA-targeting small molecules.

Integrated Biosciences focuses on developing innovative therapeutics aimed at combating age-related diseases. Founded on research from prestigious institutions such as Harvard, MIT, and UCSB, the company has made significant strides in the field, including the first AI-driven discovery of anti-aging drug candidates and the introduction of a novel structural class of antibiotics in six decades. By leveraging synthetic biology and machine learning, Integrated Biosciences seeks to control cellular stress responses, facilitating advancements in cellular rejuvenation and empowering medical professionals with next-generation treatment options.

Lemurian Labs specializes in AI infrastructure, offering a universal compute platform that streamlines training, inference, and deployment across diverse hardware. Its core product, Helix, is a Pythonic domain-specific language that optimizes code for scalable execution across chips, memory, and clusters. By combining performance, portability, and simplicity, Lemurian empowers AI teams to accelerate development, scale effortlessly, and deploy applications anywhere.

Edity Therapeutics is a biotechnology company based in Rehovot, Israel, founded in 2020 by Michal Golan Mashiach. The company focuses on developing innovative gene-editing technologies that utilize T-cell machinery for in-vivo delivery of gene-editing agents to target cells. By harnessing the immune system, Edity Therapeutics aims to deliver therapeutic proteins directly into the cytoplasm of these cells, allowing for reprogramming at the intracellular level. This approach enables various therapeutic mechanisms, including protein replacement, target modulation, genetic correction, and protein gain of function, ultimately providing physicians with tools to alter disease progression and promote cellular health.

Velontra is a technology company focused on hypersonic propulsion and aerospace solutions. Founded in 2021 and based in Cincinnati, Ohio, the company develops hypersonic unmanned aerial vehicle technology and related propulsion systems to accelerate design cycles and reduce propulsion development costs. Its work centers on engines and vehicle designs capable of hypersonic speeds, with applications in defense and space sectors.

Dawn Robotics uses augmented reality to provide products with a UI that is controlled by hand gestures using their custom UI. They attach digital assets directly to physical products, blurring the lines between virtual and real.

Margik specializes in the research, development, and manufacturing of organic electronic devices, focusing on sustainable lighting technology. They offer customizable, recyclable organic light stickers and business cards that enhance brand visibility while reducing environmental impact.

ClimateCrop develops gene editing and related plant technologies to enable crops to store more carbon and energy, with the goal of increasing yields in biomass and fruit. The approach also enhances crop resilience to extreme weather, supporting climate adaptation and more reliable production for agricultural companies. Founded in 2021 and based in Ness Ziona, the company focuses on leveraging plant energy capture to boost productivity.

Zeta Surgical is a digital surgery company dedicated to enhancing the accuracy, safety, and accessibility of image-guided procedures. It has developed an advanced navigation and robotics platform that utilizes computer vision and artificial intelligence to provide real-time image guidance at the point-of-care. This technology enables the overlay of 3D anatomical images, such as ultrasound and CT scans, directly within patients, while simultaneously tracking the positions of surgical instruments. By improving the visualization of surgical environments, Zeta Surgical's tools facilitate more effective and safer operations across various medical fields, including emergency care and interventional medicine. Founded by Harvard graduates and faculty, the company collaborates with leading hospitals and universities to advance its innovative solutions.

Pepper Bio is a trans-omics company dedicated to advancing drug discovery through the integration of various biological data types, including phosphoproteomics, proteomics, transcriptomics, and genomics. By focusing on neurodegenerative diseases, inflammatory conditions, and oncology, the company aims to develop treatments for previously untreatable diseases. Its innovative transomics platform offers comprehensive insights into biological functions, which can aid researchers and medical professionals in identifying and targeting therapeutic opportunities, ultimately enhancing the potential to cure complex diseases like cancer.

DAGsHub, Inc. is a company that offers a web platform tailored for data science, focusing on open-source tools and fostering collaboration within the open-source community. Founded in 2020 and headquartered in Dover, Delaware, DAGsHub serves as a centralized hub where data scientists and machine learning engineers can host, discover, and collaborate on projects. The platform facilitates data version control and enhances transparency in research and development processes, enabling contributions from various stakeholders. By prioritizing community involvement, DAGsHub aims to streamline the workflow for data professionals and promote innovation in the field of data science.

Forcen develops and manufactures force-sensing film for various industries, including surgical robotics, industrial robotics, and aerospace. Its film can be integrated into parts or assemblies of devices in these sectors, providing real-time force feedback. Founded in 2015, the company is headquartered in Toronto, Canada.

SAFA develops a software documentation platform designed to facilitate safety analysis. Its proprietary large language model pipeline automates document generation, maintenance, and impact analysis, ensuring information remains accessible and up-to-date regardless of system complexity. This enables software engineering teams to accelerate project timelines, free up internal resources, and deliver value quickly in complex development environments.

Karios Technologies is a developer of innovative hydrogel technology aimed at addressing significant unmet needs in surgery, drug delivery, and regenerative medicine. The company's primary focus is on the prevention of postsurgical adhesions, which can lead to complications after surgery. Their hydrogel product, once applied, binds to the heart muscle and transforms into a soft, elastic coating that serves as a protective barrier. This technology is designed to reduce postsurgical complications while allowing for necessary movement, making it applicable in various surgical fields, including cardiac, obstetric, gynecologic, and orthopedic applications. Through its advancements, Karios Technologies seeks to enhance patient outcomes by minimizing the risks associated with surgical procedures.

Electric Sheep is a technology company focused on developing artificial intelligence for outdoor applications, particularly in landscaping and grounds maintenance. The company creates robots equipped with advanced AI capabilities, aiming to replicate the transformative impact that AI has had on language through tools like ChatGPT. By leveraging Sim2Real techniques and reinforcement learning from a fleet of deployed robots, Electric Sheep enhances traditional landscape services while addressing the labor shortage in the outdoor sector. Their approach involves acquiring and modernizing conventional landscaping businesses, integrating cutting-edge technology and workflows tailored to the needs of landscaping professionals. By automating mundane and repetitive tasks, Electric Sheep allows human workers to concentrate on more creative and impactful aspects of landscaping and environmental health. Operating its own service business not only provides a practical testing ground for its robotics technology but also strengthens its competitive edge in the industry.

AcousticaBio develops technologies to reformulate intravenous biologics for subcutaneous delivery. Its advanced fluid processing platform and proprietary microgel formulation enable ultra-concentrated, small-volume subcutaneous injections of typically IV therapies, empowering patients to self-administer life-saving biologics outside hospital settings. By converting IV medicines into subcutaneous formats, the company aims to reduce pain and discomfort, minimize hospital visits, and improve convenience and access to treatment.

Stark Therapeutics is a manufacturer specializing in genetic therapies that utilize adeno-associated viral-based gene technology to address chronic diseases, including type II diabetes. The company employs a non-pathogenic virus to effectively deliver DNA to targeted tissues within the body, facilitating advanced treatment options for patients. By focusing on innovative therapeutic approaches, Stark Therapeutics aims to improve the diagnosis and management of various chronic conditions through its cutting-edge gene delivery systems.

CapSen Robotics develops advanced computer vision systems that enable machines to comprehend and navigate cluttered environments. Their core technology, derived from MIT research on 3D object detection, empowers robots and automation systems in various industries such as manufacturing, logistics, and retail inventory management.

LynkState is a technology company founded in 2021 and based in Walnut, California, specializing in digital experience monitoring applications. The company's software is designed for infrastructure operators and management, providing tools that connect real user experience monitoring with data center operations. By utilizing LynkState's application, clients can generate actionable insights and meaningful data, which support the development of effective marketing campaigns. This innovative approach bridges the gap between user experience and infrastructure management, enhancing the overall efficiency of digital operations.

Founded in 2016, Rejuvenation Technologies is a biotechnology company based in Mountain View, California. It specializes in developing nucleoside-modified TERT mRNA to safely extend telomeres for human health extension.

Mezli is a company focused on revolutionizing the food service industry through its innovative "auto-kitchens," which are fully autonomous shipping-container restaurants. By offering modern Mediterranean cuisine at affordable prices, Mezli aims to provide customers with healthy, convenient meal options for takeout and delivery. The company's robotic systems are designed to efficiently manage ingredients and assemble dishes, allowing for the preparation of cooked and packaged meals tailored to customer preferences. Mezli was founded by three individuals who, while at Stanford, recognized the need for accessible and affordable healthy food alternatives, leading them to create a solution that combines technology with culinary craftsmanship.

Barometer is a technology company that specializes in developing an AI measurement platform aimed at enhancing brand suitability in podcast advertising. The platform's primary function is to analyze podcast content for biases and various critical attributes. By leveraging artificial intelligence, Barometer offers transparent ratings that enable advertisers to access informative metrics, including levels of language formality, editorial bias, and sensationalism. This application assists companies in becoming more accountable for the biases present in their text data, ultimately promoting responsible advertising practices.

Turion Space develops spacecraft, known as 'Droids', designed to manage orbital debris and enhance operational satellite capabilities. These spacecraft rendezvous with targeted objects using vision sensors and an agnostic docking device, then employ their onboard propulsion system to either deorbit or adjust the orbit of the debris or satellite.

Talus Bio is a biotechnology company specializing in drug discovery. It focuses on developing therapies targeting challenging cancer transcription factors using its proprietary MARMOT platform, which integrates functional proteomics, automated biology, machine learning, AI, synthetic chemistry, and computational biology to design and analyze drugs, proteins, and genomics.

Simerse develops a data automation platform generating synthetic datasets to train AI and computer vision algorithms. This enables businesses to enhance their AI training using realistic datasets.

Talus Bio is a biotechnology company specializing in drug discovery. It focuses on developing therapies targeting challenging cancer transcription factors using its proprietary MARMOT platform, which integrates functional proteomics, automated biology, machine learning, AI, synthetic chemistry, and computational biology to design and analyze drugs, proteins, and genomics.

Mach9 Robotics specializes in integrated hardware and software solutions aimed at enhancing the accuracy and cost-effectiveness of utility infrastructure inspection. The company has developed a digital surveyor platform that creates multi-scale, real-time models of subsurface environments, utilizing advanced technologies such as sensors, underground penetrating radar, thermal cameras, and multi-dimensional scanners. This platform, combined with machine-learning-based mobile mapping, enables the clear mapping of underground mines, voids, pipes, and other critical infrastructure. By providing intelligent analysis software, Mach9 Robotics assists clients in simplifying infrastructure inspections and effectively planning for large construction and utility projects, as well as maintenance activities in urban settings.

SFA Therapeutics, Inc. is a development-stage biopharmaceutical company based in Jenkintown, Pennsylvania, that specializes in the development of microbiome-derived metabolites as therapeutic agents for chronic inflammatory diseases and cancer. The company focuses on harnessing compounds discovered in the human microbiome to create innovative treatments aimed at addressing conditions such as cancer, liver diseases, and autoimmune disorders. Through its novel platform, SFA Therapeutics seeks to advance the understanding and application of microbiome science in the field of medicine, providing new options for medical professionals in the treatment of these challenging health issues.

EKTO VR is a Pittsburgh-based developer of wearable locomotion technology for virtual reality, including a motorized device called Traverse and wearable robotic boots. The devices use rotating plates and wheels to simulate walking in VR, enabling users to move in a defined space while remaining in place, which helps reduce motion sickness. The technology aims to enhance the realism of training simulations and immersive VR experiences for users around the world.

Founded in 2013, Edge Case Research specializes in developing software products and safety systems for companies working on self-driving cars. They offer tools like Hologram for edge case detection and Switchboard for automated robustness testing. Their services also include embedded software best practices assessment and training. The company serves industries such as autonomous vehicles, robotics, consumer electronics, and industrial controls.

Veeve Inc. is a technology company that specializes in creating an innovative shopping cart designed to enhance the in-store shopping experience. Founded in 2018 and based in Issaquah, Washington, Veeve's smart shopping cart integrates artificial intelligence to automatically recognize products as they are added, facilitating a seamless and cashier-less checkout process. The cart features a built-in scale to calculate costs, as well as a display that offers personalized recommendations, advertising, and location-based promotions. Veeve's platform enables retailers to gain insights into customer engagement and product performance, while also improving operational efficiency. The company has attracted notable clients, including major grocery chains and local retailers, benefiting from quicker setup times and high customer satisfaction rates.

Barnstorm Agtech is a robotics-focused company specializing in swarm farming technology aimed at automating agricultural operations. Co-founded by Parker Wells, a fourth-generation farmer from Saskatchewan, and Mitchell London, who has an extensive background in technology startups, the company offers an open platform for the precision and powered deployment of various farming technologies. By concentrating on autonomous tractors and aerial drones, Barnstorm Agtech enables farmers to enhance the efficiency of their operations through advanced equipment, thereby streamlining farming processes and improving productivity.

Honeycomb Credit operates an online platform facilitating debt crowdfunding between small business owners and their communities or investors. Incorporated in 2017, the company is headquartered in Pittsburgh, Pennsylvania.

OtterTune, Inc., founded in 2020 and headquartered in Pittsburgh, Pennsylvania, offers an automated database tuning service aimed at enhancing the performance of data-intensive applications. The company’s technology continuously learns from database behavior and automatically adjusts runtime configurations, optimizing performance beyond the capabilities of traditional human database administrators. By analyzing prior tuning sessions, OtterTune's tool efficiently identifies optimal settings for database management systems, allowing developers to deploy these systems without needing extensive expertise in database administration. This innovative approach to database tuning not only reduces the time and resources required for setup but also ensures that databases operate under optimal conditions both now and in the future.

Locomation develops an AI-driven trucking technology platform that combines autonomy with driver augmentation. Its Autonomous Relay Convoy system enables trucks to follow a lead vehicle autonomously, enhancing safety and efficiency while reducing operational costs.

Underground Cellar is an online marketplace based in San Francisco that specializes in premium wine discovery and purchasing. The platform features daily themed offerings highlighting specific wineries, regions, or varietals, and enhances the consumer experience by providing random rewards in the form of free bottle swaps for rare and private-stash selections from esteemed wineries. Users can easily buy wines from various winery partners and have the option to accumulate and store up to 500 bottles in optimal conditions within a state-of-the-art wine cellar situated in California's wine country. This service allows wine enthusiasts to build their own collections and enjoy convenient home delivery.

UpContent develops a SaaS platform that discovers brand mentions and curates digital content from various sources like news articles, blogs, and social media. Its tool automates the content discovery process, allowing users to engage audiences effectively. Founded in 2015, UpContent is headquartered in Pittsburgh, Pennsylvania.

Gridwise develops a mobile application for gig economy drivers, empowering them with real-time insights to maximize earnings. Its platform offers demand alerts, passenger data tracking, mileage logging, tax deduction calculation, and performance reporting.

Onyx Labs is a technology startup developing an innovative streaming application, currently operating discreetly. Their core business involves creating infrastructure to facilitate sponsorships within live streams, aiming to enhance the monetization potential for streamers and content creators.

Catena Biosciences specializes in biotechnology, offering protein conjugation services for building biological structures and facilitating medical research. Its proprietary technology enables the attachment of proteins with high selectivity, supporting innovation in autoimmune disorders, oncology, and vaccine development.