Reinforced Ventures

Enigma Aerospace is a company dedicated to the development of autonomous aerial logistics technologies, primarily targeting the defense and business-to-business markets. The firm aims to transform logistics through innovative drone technologies, which present substantial opportunities within the global logistics and air cargo sectors. By focusing on solutions that improve the efficiency of package delivery and related logistics services, Enigma Aerospace seeks to redefine traditional logistics practices. Currently, the company operates in stealth mode, indicating a strategic approach to its market entry and product development.

Solideon specializes in Wire Arc Additive Manufacturing (WAAM) solutions aimed at large metallic component production. The company focuses on developing multi-robot, multi-tool manufacturing cells that significantly reduce production times, allowing for the creation of finished components in days rather than months. In addition to its core manufacturing capabilities, Solideon is dedicated to advancing transportation systems through innovative aerospace vehicle manufacturing. By leveraging machine-learning collaborative systems, Solideon supports the construction of vehicles and infrastructure not only on Earth but also in extraterrestrial environments such as the Moon and Mars. This approach enables space researchers to enhance their capabilities, potentially expanding economic opportunities and fostering advancements for humanity.

Biophysical Therapeutics is a biotechnology company focused on designing new drugs using computational biology. The firm has developed a pipeline of experimentally validated drug candidates targeting cancer, diseases of aging such as Alzheimer's disease, and the broader concept of aging itself. In addition to its pharmaceutical endeavors, the company is also exploring opportunities in cosmetics. Biophysical Therapeutics has a history of contributing to fundamental biology and holds a portfolio of granted patents for both preclinical and repurposed clinical-stage drugs. The company is actively pursuing longevity drug candidates aimed at slowing, halting, or reversing the aging process. Founded by Dr. Michael Forrest, a biochemistry graduate from Cambridge University with a Ph.D. in computer science, the company benefits from the advisory expertise of Professor George Church from Harvard Medical School.

Ottometric Inc. is a technology company based in Newton, Massachusetts, that specializes in developing an autonomous vehicle safety service platform. Founded in 2018, Ottometric's cloud-based platform leverages big data, artificial intelligence, sensor fusion, and computer vision to create an intelligent verification framework. This framework provides deeper insights into events and anomalies, aiding the automotive industry in enhancing the safety and reliability of advanced driver assistance systems (ADAS). As the demand for reliable ADAS features intensifies, Ottometric's scalable tools facilitate the automation and improvement of the validation and training processes, ultimately contributing to safer vehicles and potentially saving lives. The company addresses the challenges of delivering effective autonomous capabilities, which are currently viewed as inadequate by industry stakeholders.

Wayfinder Biosciences is a biotechnology company focused on developing orally available small molecule drugs that target RNA to address key disease areas, including oncology and neurodegenerative disorders. Established in 2021 and headquartered in Seattle, WA, the company utilizes a proprietary platform that integrates advanced screening technologies and computational methods to discover potent and selective RNA-targeting molecules. By employing high-throughput screening combined with machine learning and unique datasets, Wayfinder aims to accelerate the development of therapeutics for traditionally inaccessible targets, enhancing the potential for treating genetic diseases and other challenging conditions.

Integrated Biosciences focuses on developing innovative therapeutics aimed at combating age-related diseases. Founded on research from prestigious institutions such as Harvard, MIT, and UCSB, the company has made significant strides in the field, including the first AI-driven discovery of anti-aging drug candidates and the introduction of a novel structural class of antibiotics in six decades. By leveraging synthetic biology and machine learning, Integrated Biosciences seeks to control cellular stress responses, facilitating advancements in cellular rejuvenation and empowering medical professionals with next-generation treatment options.

Lemurian Labs is a company focused on revolutionizing AI infrastructure through a universal compute platform that integrates training, inference, and deployment across diverse hardware environments. Utilizing a hardware-aware compiler and a dynamic runtime, Lemurian Labs provides a cohesive software layer that replaces the fragmented tools typically used in AI development. Central to their offering is Helix, a domain-specific language that converts high-level code into optimized and scalable execution across various hardware setups. By combining performance with portability and simplicity, Lemurian Labs empowers AI teams to accelerate development, scale their solutions seamlessly, and deploy applications across multiple platforms, thereby facilitating the efficient creation of advanced AI tools for organizations of all sizes.

Edity Therapeutics is a biotechnology company based in Rehovot, Israel, founded in 2020 by Michal Golan Mashiach. The company focuses on developing innovative gene-editing technologies that utilize T-cell machinery for in-vivo delivery of gene-editing agents to target cells. By harnessing the immune system, Edity Therapeutics aims to deliver therapeutic proteins directly into the cytoplasm of these cells, allowing for reprogramming at the intracellular level. This approach enables various therapeutic mechanisms, including protein replacement, target modulation, genetic correction, and protein gain of function, ultimately providing physicians with tools to alter disease progression and promote cellular health.

Velontra is a Cincinnati-based company founded in 2021, specializing in hypersonic weapon technologies and aerospace solutions. It focuses on developing hypersonic unmanned aerial vehicle (UAV) technology that accelerates the design process while minimizing costs. Velontra's advancements include engines capable of achieving hypersonic speeds and the design and construction of propulsion systems and vehicles. This innovative approach aims to provide the defense and space industries with more affordable unmanned supersonic vehicles, enhancing operational capabilities.

Dawn Robotics uses augmented reality to provide products with a UI that is controlled by hand gestures using their custom UI. They attach digital assets directly to physical products, blurring the lines between virtual and real.

Margik is an organic electronic device manufacturing company focused on the research and development of innovative lighting technology. The company specializes in creating thin and customizable printed lighting solutions, including fully recyclable organic light stickers and business cards. These products are designed to enhance brand visibility while promoting sustainability, as they offer elevated thermal, chemical, and electronic stability. Margik's commitment to reducing greenhouse emissions from consumer use positions it as a leader in the development of sustainable consumer electronics.

ClimateCrop, founded in 2021 and based in Ness Ziona, specializes in agricultural technologies that enhance the ability of plants to store carbon and energy. The company employs gene editing techniques to optimize the performance of crops, enabling them to harness greater energy and improve resilience against extreme weather conditions. This innovative approach not only facilitates better adaptation to current and future climate challenges but also supports agricultural companies in achieving higher yields, whether in biomass or fruit production.

Zeta Surgical is a digital surgery company dedicated to enhancing the accuracy, safety, and accessibility of image-guided procedures. It has developed an advanced navigation and robotics platform that utilizes computer vision and artificial intelligence to provide real-time image guidance at the point-of-care. This technology enables the overlay of 3D anatomical images, such as ultrasound and CT scans, directly within patients, while simultaneously tracking the positions of surgical instruments. By improving the visualization of surgical environments, Zeta Surgical's tools facilitate more effective and safer operations across various medical fields, including emergency care and interventional medicine. Founded by Harvard graduates and faculty, the company collaborates with leading hospitals and universities to advance its innovative solutions.

Pepper Bio is a trans-omics company dedicated to advancing drug discovery through the integration of various biological data types, including phosphoproteomics, proteomics, transcriptomics, and genomics. By focusing on neurodegenerative diseases, inflammatory conditions, and oncology, the company aims to develop treatments for previously untreatable diseases. Its innovative transomics platform offers comprehensive insights into biological functions, which can aid researchers and medical professionals in identifying and targeting therapeutic opportunities, ultimately enhancing the potential to cure complex diseases like cancer.

DAGsHub, Inc. is a company that offers a web platform tailored for data science, focusing on open-source tools and fostering collaboration within the open-source community. Founded in 2020 and headquartered in Dover, Delaware, DAGsHub serves as a centralized hub where data scientists and machine learning engineers can host, discover, and collaborate on projects. The platform facilitates data version control and enhances transparency in research and development processes, enabling contributions from various stakeholders. By prioritizing community involvement, DAGsHub aims to streamline the workflow for data professionals and promote innovation in the field of data science.

Forcen Inc. is a Canadian company specializing in the development and manufacture of force-sensing film technology for various applications, including surgical robotics, industrial robotics, and the aerospace and defense sectors. Founded in 2015 and headquartered in Toronto, Forcen's innovative force-sensing film can be integrated into medical devices, enabling real-time force feedback for surgeons and enhancing precision during procedures. This technology accurately measures the forces applied at the tool's tip and wirelessly transmits this information, thereby improving operational safety and reducing complications. As a tier 1 supplier, Forcen also provides comprehensive sensing networks for robotics original equipment manufacturers (OEMs), facilitating advanced force and torque sensor systems.

Safa is a company focused on enhancing safety analysis through a traceability platform that integrates artificial intelligence. The platform is designed to streamline the processes of traceability and impact analysis, allowing software engineering teams to efficiently assess the implications of their changes in complex development environments. By reducing the cost and effort involved in evolving and reusing safety cases, Safa aims to maintain high safety standards while facilitating more efficient software development practices.

Karios Technologies is a developer of innovative hydrogel technology aimed at addressing significant unmet needs in surgery, drug delivery, and regenerative medicine. The company's primary focus is on the prevention of postsurgical adhesions, which can lead to complications after surgery. Their hydrogel product, once applied, binds to the heart muscle and transforms into a soft, elastic coating that serves as a protective barrier. This technology is designed to reduce postsurgical complications while allowing for necessary movement, making it applicable in various surgical fields, including cardiac, obstetric, gynecologic, and orthopedic applications. Through its advancements, Karios Technologies seeks to enhance patient outcomes by minimizing the risks associated with surgical procedures.

Electric Sheep is a technology company focused on developing artificial intelligence for outdoor applications, particularly in landscaping and grounds maintenance. The company creates robots equipped with advanced AI capabilities, aiming to replicate the transformative impact that AI has had on language through tools like ChatGPT. By leveraging Sim2Real techniques and reinforcement learning from a fleet of deployed robots, Electric Sheep enhances traditional landscape services while addressing the labor shortage in the outdoor sector. Their approach involves acquiring and modernizing conventional landscaping businesses, integrating cutting-edge technology and workflows tailored to the needs of landscaping professionals. By automating mundane and repetitive tasks, Electric Sheep allows human workers to concentrate on more creative and impactful aspects of landscaping and environmental health. Operating its own service business not only provides a practical testing ground for its robotics technology but also strengthens its competitive edge in the industry.

AcousticaBio is a biotechnology company focused on reformulating intravenous medications for subcutaneous administration. It has developed a fluid processing technology that enables the creation of complex microparticles necessary for effective subcutaneous formulations. By converting intravenously delivered biologic products into highly concentrated, small-volume injections, AcousticaBio aims to enhance patient experiences by allowing for self-administration of life-saving medications. This innovation significantly reduces the pain and discomfort associated with traditional delivery methods and minimizes the need for lengthy hospital visits, improving accessibility and convenience for patients.

Stark Therapeutics is a manufacturer specializing in genetic therapies that utilize adeno-associated viral-based gene technology to address chronic diseases, including type II diabetes. The company employs a non-pathogenic virus to effectively deliver DNA to targeted tissues within the body, facilitating advanced treatment options for patients. By focusing on innovative therapeutic approaches, Stark Therapeutics aims to improve the diagnosis and management of various chronic conditions through its cutting-edge gene delivery systems.

CapSen Robotics, Inc. specializes in advanced 3D computer vision systems that empower computers and robots to effectively interpret and navigate the cluttered physical world. Founded in 2016 and based in Pittsburgh, Pennsylvania, the company develops a range of solutions including cluttered object detection, scanning for both large and small objects, and object tracking. These technologies are applicable across various sectors such as factory automation, vehicle scanning and measuring, and retail inventory management. CapSen Robotics leverages cutting-edge research from MIT to enhance the capabilities of robotic systems, enabling them to operate in less structured environments like hospitals, warehouses, and homes. The company is currently collaborating with system integrators and robotics firms on applications that involve robotic picking and has partnered with a leading government contractor for warehouse applications. Their innovations are poised to have a significant impact across consumer, industrial, and defense markets.

LynkState is a technology company founded in 2021 and based in Walnut, California, specializing in digital experience monitoring applications. The company's software is designed for infrastructure operators and management, providing tools that connect real user experience monitoring with data center operations. By utilizing LynkState's application, clients can generate actionable insights and meaningful data, which support the development of effective marketing campaigns. This innovative approach bridges the gap between user experience and infrastructure management, enhancing the overall efficiency of digital operations.

Rejuvenation Technologies Inc., established in 2016 and based in Mountain View, California, is a biotechnology company specializing in developing nucleoside-modified TERT mRNA. This technology safely and rapidly extends telomeres, enabling cells to proliferate more effectively. The company focuses on regenerative medicine applications, aiming to target age-related diseases and conditions across various organs such as the liver, lungs, and immune system. Their offerings include cell therapies like tissue engineering, transplants, skin grafts, immunotherapy, and regeneration medicine.

Mezli is a company focused on revolutionizing the food service industry through its innovative "auto-kitchens," which are fully autonomous shipping-container restaurants. By offering modern Mediterranean cuisine at affordable prices, Mezli aims to provide customers with healthy, convenient meal options for takeout and delivery. The company's robotic systems are designed to efficiently manage ingredients and assemble dishes, allowing for the preparation of cooked and packaged meals tailored to customer preferences. Mezli was founded by three individuals who, while at Stanford, recognized the need for accessible and affordable healthy food alternatives, leading them to create a solution that combines technology with culinary craftsmanship.

Barometer is a technology company that specializes in developing an AI measurement platform aimed at enhancing brand suitability in podcast advertising. The platform's primary function is to analyze podcast content for biases and various critical attributes. By leveraging artificial intelligence, Barometer offers transparent ratings that enable advertisers to access informative metrics, including levels of language formality, editorial bias, and sensationalism. This application assists companies in becoming more accountable for the biases present in their text data, ultimately promoting responsible advertising practices.

Turion Space specializes in developing and operating "Droid" spacecraft designed for orbital debris removal and satellite servicing. These spacecraft are equipped with vision sensors and agnostic docking devices, allowing them to rendezvous and dock with both operational satellites and large debris objects. Using their onboard propulsion systems, the Droid spacecraft can either deorbit or change the orbit of these targets, thereby enhancing mission capabilities, extending operational lifetimes, and contributing to a sustainable space environment by mitigating the growing issue of orbital debris.

Talus Bio is a biotechnology startup focused on drug discovery and development, particularly targeting challenging cancer transcription factors. The company employs an innovative approach that integrates functional proteomics, automated biology, and machine learning. Their MARMOT platform utilizes AI, advanced proteomics, synthetic chemistry, and computational biology to design and analyze drugs, proteins, and genomics. This platform is designed to advance drug development for gene regulation in oncology, aiming to create small-molecule therapies that can effectively control gene expression in cancer cells.

Simerse is a venture capital-backed company focused on advancing artificial intelligence and digital technologies within the energy and infrastructure sectors. It has developed a data automation platform that provides synthetic datasets tailored for training AI and computer vision algorithms. By generating computer-simulated datasets that closely resemble real-world conditions, Simerse enables organizations to enhance their AI training processes with photorealistic data. This innovative approach is particularly beneficial for businesses seeking to improve the performance and reliability of their AI and machine learning applications.

Talus Bio is a biotechnology startup focused on drug discovery and development, particularly targeting challenging cancer transcription factors. The company employs an innovative approach that integrates functional proteomics, automated biology, and machine learning. Their MARMOT platform utilizes AI, advanced proteomics, synthetic chemistry, and computational biology to design and analyze drugs, proteins, and genomics. This platform is designed to advance drug development for gene regulation in oncology, aiming to create small-molecule therapies that can effectively control gene expression in cancer cells.

Mach9 Robotics specializes in integrated hardware and software solutions aimed at enhancing the accuracy and cost-effectiveness of utility infrastructure inspection. The company has developed a digital surveyor platform that creates multi-scale, real-time models of subsurface environments, utilizing advanced technologies such as sensors, underground penetrating radar, thermal cameras, and multi-dimensional scanners. This platform, combined with machine-learning-based mobile mapping, enables the clear mapping of underground mines, voids, pipes, and other critical infrastructure. By providing intelligent analysis software, Mach9 Robotics assists clients in simplifying infrastructure inspections and effectively planning for large construction and utility projects, as well as maintenance activities in urban settings.

SFA Therapeutics, Inc. is a development-stage biopharmaceutical company based in Jenkintown, Pennsylvania, that specializes in the development of microbiome-derived metabolites as therapeutic agents for chronic inflammatory diseases and cancer. The company focuses on harnessing compounds discovered in the human microbiome to create innovative treatments aimed at addressing conditions such as cancer, liver diseases, and autoimmune disorders. Through its novel platform, SFA Therapeutics seeks to advance the understanding and application of microbiome science in the field of medicine, providing new options for medical professionals in the treatment of these challenging health issues.

EKTO VR, Inc. is a technology company based in Pittsburgh, Pennsylvania, focused on developing innovative solutions for virtual reality experiences. Incorporated in 2018, EKTO VR specializes in wearable robotic boots that facilitate locomotion within virtual environments. These boots are engineered with rotating plates that adapt to the user’s walking direction and a unique wheel system that creates a natural walking sensation while allowing individuals to remain stationary. This design not only enhances the realism of training simulations but also aims to reduce motion sickness, providing users with an immersive experience without the risks associated with physical movement in real space. EKTO VR's products are particularly geared towards enhancing virtual reality games and training applications, making it a significant player in the evolving landscape of immersive technology.

Edge Case Research is a company based in Pittsburgh, Pennsylvania, with an additional office in Unterschleißheim, Germany, specializing in developing software products and safety systems for companies involved in self-driving car technology. Founded in 2013, the firm focuses on testing vehicle software and artificial intelligence without requiring physical vehicles. Its key offerings include Hologram, a platform for identifying and addressing edge cases that challenge machine learning, and Switchboard, a cloud-based tool for automated robustness testing of complex software. The company employs Model-based Iterative System Safety Analysis to pinpoint and model safety risks in intricate systems. Additionally, Edge Case Research provides embedded software best practices assessment and training services. It serves industries such as autonomous vehicles and robotics, consumer electronics and the Internet of Things, and industrial controls and embedded systems.

Veeve Inc. is a technology company that specializes in creating an innovative shopping cart designed to enhance the in-store shopping experience. Founded in 2018 and based in Issaquah, Washington, Veeve's smart shopping cart integrates artificial intelligence to automatically recognize products as they are added, facilitating a seamless and cashier-less checkout process. The cart features a built-in scale to calculate costs, as well as a display that offers personalized recommendations, advertising, and location-based promotions. Veeve's platform enables retailers to gain insights into customer engagement and product performance, while also improving operational efficiency. The company has attracted notable clients, including major grocery chains and local retailers, benefiting from quicker setup times and high customer satisfaction rates.

Barnstorm Agtech is a robotics-focused company specializing in swarm farming technology aimed at automating agricultural operations. Co-founded by Parker Wells, a fourth-generation farmer from Saskatchewan, and Mitchell London, who has an extensive background in technology startups, the company offers an open platform for the precision and powered deployment of various farming technologies. By concentrating on autonomous tractors and aerial drones, Barnstorm Agtech enables farmers to enhance the efficiency of their operations through advanced equipment, thereby streamlining farming processes and improving productivity.

Honeycomb Credit, Inc. operates a peer-to-peer lending platform that connects small business owners with individual investors seeking to fund those businesses. Founded in 2017 and based in Pittsburgh, Pennsylvania, the company allows businesses to secure loans from their own customers and community members, facilitating debt crowdfunding. This innovative approach enables small businesses to obtain necessary capital without relinquishing equity, thus supporting their growth while providing a unique investment opportunity for lenders. By bridging the gap between traditional funding sources and community support, Honeycomb Credit enhances access to financial resources for small enterprises.

OtterTune, Inc., founded in 2020 and headquartered in Pittsburgh, Pennsylvania, offers an automated database tuning service aimed at enhancing the performance of data-intensive applications. The company’s technology continuously learns from database behavior and automatically adjusts runtime configurations, optimizing performance beyond the capabilities of traditional human database administrators. By analyzing prior tuning sessions, OtterTune's tool efficiently identifies optimal settings for database management systems, allowing developers to deploy these systems without needing extensive expertise in database administration. This innovative approach to database tuning not only reduces the time and resources required for setup but also ensures that databases operate under optimal conditions both now and in the future.

Locomation, Inc. is a Pittsburgh-based company that specializes in developing a trucking technology platform that integrates artificial intelligence with driver assistance. Founded in 2016, Locomation focuses on enhancing safety and efficiency in the trucking industry through its Autonomous Relay Convoy (ARC) system. This innovative approach features a human-guided autonomous system where one truck follows another, allowing for a combination of human oversight and automation. The company's technology aims to reduce trucking costs while minimizing accidents, catering to both commercial and defense applications.

Underground Cellar is an online marketplace based in San Francisco that specializes in premium wine discovery and purchasing. The platform features daily themed offerings highlighting specific wineries, regions, or varietals, and enhances the consumer experience by providing random rewards in the form of free bottle swaps for rare and private-stash selections from esteemed wineries. Users can easily buy wines from various winery partners and have the option to accumulate and store up to 500 bottles in optimal conditions within a state-of-the-art wine cellar situated in California's wine country. This service allows wine enthusiasts to build their own collections and enjoy convenient home delivery.

UpContent, LLC is a technology company based in Pittsburgh, Pennsylvania, that specializes in content discovery and curation. Founded in 2015, it offers a software-as-a-service (SaaS) platform designed to help marketing, sales, and human resource teams efficiently discover and share relevant third-party digital content. The platform automates the content discovery process, allowing users to find brand mentions and engage their audiences through various channels, including social media. It features UpContent Gallery, which enables users to curate content, create custom calls-to-action, and implement retargeting strategies to capture traffic. By streamlining the content curation process, UpContent empowers organizations to enhance their communication and establish thought leadership in their respective fields.

Gridwise, Inc. is a technology company based in Pittsburgh, Pennsylvania, that specializes in developing a mobile application designed for rideshare and delivery drivers. Founded in 2016, Gridwise offers a comprehensive platform that assists gig economy drivers in maximizing their earnings and enhancing their business operations. The application provides real-time insights on passenger demand, traffic, and weather, as well as alerts for nearby opportunities. Additionally, it features tools for tracking mileage, calculating tax deductions, and generating detailed tax reports. With its focus on performance tracking and earnings analysis, Gridwise empowers hundreds of thousands of drivers across the United States to effectively manage their gig work.

Onyx Labs is a technology startup developing an innovative streaming application, currently operating discreetly. Their core business involves creating infrastructure to facilitate sponsorships within live streams, aiming to enhance the monetization potential for streamers and content creators.

Catena Biosciences is a biotechnology firm focused on advancing protein conjugation technology to address autoimmune disorders and other medical challenges. The company specializes in a method that facilitates the rapid and selective attachment of proteins, utilizing natural amino acids such as tyrosine and cysteine. This innovative approach allows researchers to develop novel therapeutics across various fields, including autoimmune disorders, oncology, and vaccine development. By streamlining the process of building biologic structures, Catena Biosciences aims to enhance medical research and contribute to the creation of effective treatments.