Soffinova Partners
Sofinnova Partners is an independent venture capital firm headquartered in Paris, France, with a focus on the life sciences sector, including biopharmaceuticals, biotechnology, medical devices, and industrial biotechnology. Over its 45-year history, the firm has financed nearly 500 companies, primarily targeting start-ups, early-stage ventures, corporate spin-offs, and occasional turnaround situations. Sofinnova Partners actively sources investment opportunities and often serves as the first institutional investor in Series A financings, taking a lead role in its portfolio companies. The firm engages closely with entrepreneurs from the formation phase, holding board positions and guiding companies through their development until exit. While primarily investing throughout Europe, Sofinnova Partners also allocates a portion of its investments globally.
GFBiochemicals is the only company to produce levulinic acid at commercial scale directly from biomass. In 2008, a group of biobased chemical experts saw the significant potential of levulinic acid to replace petroleum-based products across a range of market sectors. GFBiochemicals was founded to develop the production technology needed for this revolution in chemicals and biofuels. GFBiochemicals demonstrated these breakthrough technologies in the Caserta plant, in partnership with the University of Pisa and the Polytechnic University of Milan. This commercial-scale plant was retrofitted with new conversion, recovery and purification technology.
Alia Therapeutics is developing next-generation gene-editing medicines to cure rare genetic diseases.
AAVantgarde Bio is focused on developing innovative gene therapies specifically for inherited retinal disorders. The company utilizes proprietary Adeno-Associated Viral (AAV) vector platforms to overcome the limitations associated with the cargo capacity of traditional AAV vectors. This technology allows for the delivery of larger genes to both ocular and non-ocular tissues, enhancing the potential for effective treatment in patients. By addressing these challenges, AAVantgarde Bio aims to advance the field of gene therapy and improve outcomes for individuals affected by genetic eye diseases.
Borea Therapeutics is advancing a new generation of gene therapies that would enable the targeting of specific tissues and cells.
Enthera S.r.l. is a biotechnology company based in Milan, Italy, founded in 2016. The company focuses on developing innovative therapeutic approaches for diabetes and related gastrointestinal complications, particularly enteropathy, along with other intestinal disorders that share similar biological pathways. Enthera operates a monoclonal antibody discovery platform to create first-in-class biologics aimed at addressing these underserved conditions. The company was established as a subsidiary of BiovelocITA S.r.l. and was founded in collaboration with scientists Prof. Paolo Fiorina and Dr. Francesca D’Addio. The name "Enthera" is derived from a combination of the terms "entero," referring to the intestine, and "therapy," reflecting its commitment to developing targeted treatments.
PinCell is a biotech company focused on the research of therapeutic molecules based on new targets related to the pathomechanisms of inflammatory and neoplastic skin diseases.
Genespire is a biotechnology company focused on the development of transformative gene therapies for patients affected by genetic diseases, particularly primary immunodeficiencies and inherited metabolic diseases.
Epsilen Bio Srl, founded in December 2019 and based in Milan, Italy, focuses on developing innovative therapies for patients with underserved medical conditions. The company is dedicated to creating transformative treatments through a process known as epigenetic silencing, which aims to achieve stable genomic silencing of genes implicated in various pathological processes. By targeting these specific genes, Epsilen Bio seeks to address significant unmet medical needs and improve patient outcomes.
Enthera S.r.l. is a biotechnology company based in Milan, Italy, founded in 2016. The company focuses on developing innovative therapeutic approaches for diabetes and related gastrointestinal complications, particularly enteropathy, along with other intestinal disorders that share similar biological pathways. Enthera operates a monoclonal antibody discovery platform to create first-in-class biologics aimed at addressing these underserved conditions. The company was established as a subsidiary of BiovelocITA S.r.l. and was founded in collaboration with scientists Prof. Paolo Fiorina and Dr. Francesca D’Addio. The name "Enthera" is derived from a combination of the terms "entero," referring to the intestine, and "therapy," reflecting its commitment to developing targeted treatments.
EryDel S.p.A. engages in the production and commercialization of drug delivery based on the use of autologous erythrocytes. The company provides medical devices which includes red cell loader, and erykit. The company was founded in 2007 and is based in Urbino, Italy.
Creabilis SA is a clinical stage biotechnology company based in Luxembourg City, specializing in the research and development of new drugs for dermatology and inflammatory diseases. Founded in 2003, the company has developed a diverse pipeline of clinical and pre-clinical drug candidates, addressing significant unmet medical needs in skin disorders. Notable products in its portfolio include CT327, a TrkA kinase inhibitor aimed at treating psoriasis and atopic dermatitis; CT340, which targets both TrkA and MAP2K3 kinases for inflammatory arthritis and pain; and CT637, an HMGB1 antagonist for various inflammatory conditions. Creabilis also engages in early-stage projects to explore additional treatment options. With research offices in Ivrea, Italy, and development operations in Canterbury, United Kingdom, the company aims to market its innovative therapies either independently or through partnerships.
EOS is a biopharmaceutical company committed to the development of novel medicines for the treatment of cancer.EOS S.p.A. was founded in June 2006 by Silvano Spinelli, Gabriella Camboni, and Ennio Cavalletti along with Jacques Theurillat. Company’s operations were seed and further financed by founders and by Sofinnova Partners since its inception. EOS is a privately held organization headquartered in Via Monte di Pietà, 1/A, Milano, Italy.
Creabilis SA is a clinical stage biotechnology company based in Luxembourg City, specializing in the research and development of new drugs for dermatology and inflammatory diseases. Founded in 2003, the company has developed a diverse pipeline of clinical and pre-clinical drug candidates, addressing significant unmet medical needs in skin disorders. Notable products in its portfolio include CT327, a TrkA kinase inhibitor aimed at treating psoriasis and atopic dermatitis; CT340, which targets both TrkA and MAP2K3 kinases for inflammatory arthritis and pain; and CT637, an HMGB1 antagonist for various inflammatory conditions. Creabilis also engages in early-stage projects to explore additional treatment options. With research offices in Ivrea, Italy, and development operations in Canterbury, United Kingdom, the company aims to market its innovative therapies either independently or through partnerships.