Topspin Consumer Partners

Topspin Partners is a New York-based investment firm, founded in 2001, that specializes in lower mid-market investments primarily within the consumer sectors across the United States. The firm, which is the successor to the Long Island Venture Fund, is affiliated with Renaissance Technologies. Topspin focuses on investing in companies involved in areas such as health and wellness, fitness, household goods, personal care, beauty, e-commerce, pet products, children's items, food and beverage, digital media, outdoor and leisure, and apparel. By partnering with management teams, Topspin aims to build strong companies and generate superior returns for its investors.

Nick Fazzari

Vice President

Frank Guiliano

Principal

Walter B. Kissinger

Managing Director

Matthew Michelson

Associate

Stephen Parks

Partner

Leigh J. Randall

Co-Founder, Managing Partner and Head of Investment Committee

Ekta Sharma

Principal

Josh Shaw

Operating Partner

Suha Surapaneni

Associate

Ojas Vahia

Partner and Member of the Investment Committee

Jason Wargon

Vice President of Finance

Macy Weir

Associate

59 past transactions

Mission Product Holdings

Private Equity Round in 2022
Mission Product Holdings, Inc. specializes in manufacturing and distributing athletic and performance apparel and accessories for both men and women. The company offers a diverse range of products, including t-shirts, tank tops, jackets, shorts, leggings, and accessories such as cooling towels and headbands. Notably, Mission is recognized for its innovative athlete-engineered products aimed at enhancing performance during training and competition. Its portfolio features advanced thermo-regulation technology that helps control body temperature, thereby improving athletic performance. The company markets its temperature control products under various brand names, including HydroActive MAX, RadiantActive, and Vaporactive. Mission Product Holdings was incorporated in 2007 and is headquartered in New York, New York, with products available through online retail channels.

Coop Home Goods

Private Equity Round in 2021
Manufacturer of bedding products intended to enhance the sleeping experience. The company specializes in adjustable pillows that allow people with any body type and sleep position to be aligned by adjusting the quality of fill and is made using breathable materials to ensure proper airflow, thereby enabling customers to have a functional and comfortable sleep.

SportPet

Private Equity Round in 2021
Manufacturer of kennels and beds intended for pet animals. The company manufactures elevated dog beds, deluxe mattress beds, cat carriers and luxury sofa beds, providing customers with good quality, environmentally responsible and safe products for their pets.

reCommerce

Venture Round in 2020
reCommerce Brands operates as an e-commerce platform for Amazon brand products. Its services include creative services, brand protection, brand optimization, streamlined distribution, and data reporting. The company was founded in 2013 and is based in Deerfield Beach, Florida.

Codagenix

Series B in 2020
Codagenix, Inc. is a biotechnology company based in Farmingdale, New York, focused on developing live-attenuated viral vaccines for various diseases, including influenza, dengue, respiratory syncytial virus, and polio. The company utilizes its proprietary Synthetic Attenuated Virus Engineering (SAVE) technology, which employs computer-based rational design to construct viral genomes, allowing for the creation of innovative vaccine strains. In addition to human vaccines, Codagenix also provides agricultural and companion animal vaccines. The company has also been engaged in the development of a COVID-19 vaccine, showcasing its commitment to addressing current health challenges. Codagenix was incorporated in 2009 and emphasizes the use of synthetic biology in its vaccine development processes.

PMV Pharmaceuticals

Series C in 2019
PMV Pharma is developing first-in-class p53 and p53 pathway modulators for the treatment of cancer. Bringing together leaders in the field to utilize over three decades of p53 biology, PMV Pharma combines unique biological understanding with pharmaceutical development focus.

Japonesque

Acquisition in 2019
Japonesque LLC, established in 1984 and headquartered in San Ramon, California, specializes in beauty care products aimed at makeup artists and beauty professionals. The company offers a diverse range of items, including cosmetics, makeup brushes, eyelash curlers, nail clippers, and skincare products. Drawing inspiration from the professional makeup tools used in Kabuki theater, Japonesque combines high-impact color and long-wear textures in its offerings, which cater to discerning makeup enthusiasts. Its products are available through various retailers in the United States and internationally via beauty supply stores, salons, and spas. With nearly four decades of expertise, Japonesque continues to provide essential beauty tools and accessories that reflect the artistry and innovation of the beauty industry.

SetPoint Medical

Venture Round in 2019
SetPoint Medical Corporation is a clinical-stage bioelectronic medicine company based in Valencia, California, focused on developing implantable neuromodulation devices for treating chronic inflammatory diseases, including rheumatoid arthritis and Crohn's Disease. The company leverages the Inflammatory Reflex, a natural mechanism that allows the central nervous system to regulate the immune system, which has been extensively studied and documented in scientific literature. SetPoint's proprietary microregulator aims to enhance this reflex through vagus nerve stimulation, offering an alternative treatment option that provides systemic anti-inflammatory effects. The devices are designed to supplement the body's natural responses and are expected to deliver comparable anti-inflammatory potency to leading medications, while potentially offering improved safety and lower costs. Currently, SetPoint is conducting human trials for its technology at multiple centers in Europe.

ORIC Pharmaceuticals

Series D in 2019
ORIC Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing therapies to overcome resistance in cancer treatment. Founded in 2014 and based in South San Francisco, California, the company is advancing several product candidates, including ORIC-101, a small molecule antagonist of the glucocorticoid receptor associated with resistance to various cancer therapies in solid tumors. Another key candidate, ORIC-533, is an orally bioavailable small molecule inhibitor of CD73, which plays a significant role in resistance to chemotherapy and immunotherapy regimens. In addition to these, ORIC is working on multiple precision medicines aimed at addressing other cancer resistance mechanisms. The company's founders, Charles Sawyers and Scott Lowe, are recognized for their contributions to identifying novel cancer targets that have led to innovative treatment options.

Rapt

Series C in 2019
RAPT Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in South San Francisco, California, specializing in the discovery and development of oral small molecule therapies for oncology and inflammatory diseases. The company is focused on addressing significant unmet medical needs through its proprietary discovery engine. Its lead oncology candidate, FLX475, is a C-C motif chemokine receptor 4 antagonist currently undergoing Phase 2 clinical trials, both as a monotherapy and in combination with pembrolizumab, for various tumor types. Additionally, RAPT's lead inflammation drug candidate, RPT193, aims to selectively inhibit the migration of type 2 T helper cells into allergically inflamed tissues. The company is also exploring other potential targets, including general control nonderepressible 2 and hematopoietic progenitor kinase 1, which are in the discovery phase. Founded in 2015, RAPT Therapeutics was previously known as FLX Bio, Inc. before its name change in May 2019.

Celmatix

Venture Round in 2019
Celmatix is a preclinical-stage women’s health biotech focused uniquely on ovarian biology. With a lead program in ovarian senescence and collaborations in PCOS and non-hormonal contraception with industry leaders, Celmatix is addressing areas of high unmet need by developing the next generation of interventions and pioneering advancements in ovarian health.

Peloton Therapeutics

Series E in 2019
Peloton Therapeutics, Inc. is a clinical stage biopharmaceutical company based in Dallas, Texas, focused on developing innovative medicines for cancer and other serious conditions. The company's lead candidate, PT2977, is an oral HIF-2a inhibitor currently undergoing Phase 2 clinical trials for advanced or metastatic clear cell renal cell carcinoma. Additionally, Peloton is exploring PT2977 in various other indications, including von Hippel-Lindau disease-associated renal cell carcinoma and glioblastoma multiforme, as well as in combination therapies for metastatic renal cell carcinoma. Furthermore, Peloton is developing PT2567, another oral HIF-2a inhibitor in preclinical stages aimed at non-oncology applications, notably pulmonary arterial hypertension. Founded in 2010 and initially known as Damascus Pharmaceutics, Peloton Therapeutics has formed strong partnerships with academic institutions and secured funding from organizations like the Cancer Prevention Research Institute of Texas, positioning itself as a key player in the biotech sector.
Constellation Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company based in Cambridge, Massachusetts, focused on developing therapeutics aimed at addressing significant unmet medical needs in cancer treatment, particularly those related to abnormal gene expression and drug resistance. The company's lead product candidates include CPI-0610, currently undergoing Phase II clinical trials for myelofibrosis in combination with ruxolitinib, and CPI-1205, which is in Phase Ib/II trials for metastatic castration-resistant prostate cancer alongside androgen receptor signaling inhibitors. Additionally, Constellation is developing CPI-0209, which is in the dose escalation phase of a Phase I/II clinical trial for solid tumors. Founded in 2008, the company was previously known as Epigenetix, Inc. and has established itself as a pioneer in the emerging field of epigenetics, which focuses on selective regulators of epigenetic function crucial for gene expression control.

Rapt

Series C in 2017
RAPT Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in South San Francisco, California, specializing in the discovery and development of oral small molecule therapies for oncology and inflammatory diseases. The company is focused on addressing significant unmet medical needs through its proprietary discovery engine. Its lead oncology candidate, FLX475, is a C-C motif chemokine receptor 4 antagonist currently undergoing Phase 2 clinical trials, both as a monotherapy and in combination with pembrolizumab, for various tumor types. Additionally, RAPT's lead inflammation drug candidate, RPT193, aims to selectively inhibit the migration of type 2 T helper cells into allergically inflamed tissues. The company is also exploring other potential targets, including general control nonderepressible 2 and hematopoietic progenitor kinase 1, which are in the discovery phase. Founded in 2015, RAPT Therapeutics was previously known as FLX Bio, Inc. before its name change in May 2019.

Remedy Health Media

Acquisition in 2017
Remedy Health Media is an operator of a digital health platform intended to provide health-related information that produces, publishes, and distributes health magazines to consumers and caregivers. It offers content, tools, and real stories related to consumer health and wellness through the development of authentic communities of health information seekers who can interact and learn from a relatable physician, pharmacist, public health, and patient experts that enable the customers to make informed choices about their health and well-being. The company's mission is to empower patients and caregivers with the information and applications needed to efficiently navigate the healthcare landscape and as a result, to permit better health outcomes through the use of its products and services. Remedy Health Media was established in 1994 and is headquartered in New York.

Bear Down Brands

Venture Round in 2017
Bear Down Brands is a network of consumer brands that each focus on premium home, health, and personal care products.Bear Down Brands mission is to create elegant, practical, and innovative products that enhance the way you care for yourself and the world around you.Bear Down's focus has been on developing a well-rounded product portfolio while providing advanced product technologies, award-winning customer support, and strong brand relationships with our consumers.

Codagenix

Venture Round in 2017
Codagenix, Inc. is a biotechnology company based in Farmingdale, New York, focused on developing live-attenuated viral vaccines for various diseases, including influenza, dengue, respiratory syncytial virus, and polio. The company utilizes its proprietary Synthetic Attenuated Virus Engineering (SAVE) technology, which employs computer-based rational design to construct viral genomes, allowing for the creation of innovative vaccine strains. In addition to human vaccines, Codagenix also provides agricultural and companion animal vaccines. The company has also been engaged in the development of a COVID-19 vaccine, showcasing its commitment to addressing current health challenges. Codagenix was incorporated in 2009 and emphasizes the use of synthetic biology in its vaccine development processes.

Pure Enrichment

Acquisition in 2017
Pure Enrichment is the manufacturer of premium home, health, and personal care products.

SetPoint Medical

Series D in 2017
SetPoint Medical Corporation is a clinical-stage bioelectronic medicine company based in Valencia, California, focused on developing implantable neuromodulation devices for treating chronic inflammatory diseases, including rheumatoid arthritis and Crohn's Disease. The company leverages the Inflammatory Reflex, a natural mechanism that allows the central nervous system to regulate the immune system, which has been extensively studied and documented in scientific literature. SetPoint's proprietary microregulator aims to enhance this reflex through vagus nerve stimulation, offering an alternative treatment option that provides systemic anti-inflammatory effects. The devices are designed to supplement the body's natural responses and are expected to deliver comparable anti-inflammatory potency to leading medications, while potentially offering improved safety and lower costs. Currently, SetPoint is conducting human trials for its technology at multiple centers in Europe.

Hubble

Pre Seed Round in 2017
Developer of location-based questions and answers application designed to discover like-minded individuals and communicate outside of their regular meetups. The company's application allows users to retrieve hyperlocal information by asking queries to nearby people and getting answers from them, enabling users to save time browsing through reviews and websites for retrieving information.
Constellation Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company based in Cambridge, Massachusetts, focused on developing therapeutics aimed at addressing significant unmet medical needs in cancer treatment, particularly those related to abnormal gene expression and drug resistance. The company's lead product candidates include CPI-0610, currently undergoing Phase II clinical trials for myelofibrosis in combination with ruxolitinib, and CPI-1205, which is in Phase Ib/II trials for metastatic castration-resistant prostate cancer alongside androgen receptor signaling inhibitors. Additionally, Constellation is developing CPI-0209, which is in the dose escalation phase of a Phase I/II clinical trial for solid tumors. Founded in 2008, the company was previously known as Epigenetix, Inc. and has established itself as a pioneer in the emerging field of epigenetics, which focuses on selective regulators of epigenetic function crucial for gene expression control.

PMV Pharmaceuticals

Series B in 2017
PMV Pharma is developing first-in-class p53 and p53 pathway modulators for the treatment of cancer. Bringing together leaders in the field to utilize over three decades of p53 biology, PMV Pharma combines unique biological understanding with pharmaceutical development focus.

Palmetto Moon

Acquisition in 2016
Palmetto Moon, LLC is a retail company based in Charleston, South Carolina, specializing in apparel, footwear, and gifts for men, women, and children. Founded in 2002, it offers a wide range of products, including T-shirts, jackets, dresses, accessories, and footwear such as sandals and boots. The company emphasizes collegiate, coastal, and southern living in its product offerings, which also include home goods like blankets, décor, and outdoor gear. Palmetto Moon operates multiple store locations throughout the southeastern United States, including cities in North Carolina and South Carolina, and provides an online shopping platform to reach a broader customer base.

Texas Family Fitness

Acquisition in 2016
Texas Family Fitness, LLC operates a network of health and fitness clubs across Texas, with locations in Coppell, The Colony, Frisco, Plano, and Allen. The company provides a family-friendly environment featuring state-of-the-art equipment and a variety of fitness options, including cardio, dance, yoga, and strength training classes. Personal training services are also available at an affordable monthly rate. By focusing on a family-oriented approach, Texas Family Fitness aims to create a healthy atmosphere for all members while maintaining competitive pricing that offers better value than local competitors.

Rapt

Series B in 2016
RAPT Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in South San Francisco, California, specializing in the discovery and development of oral small molecule therapies for oncology and inflammatory diseases. The company is focused on addressing significant unmet medical needs through its proprietary discovery engine. Its lead oncology candidate, FLX475, is a C-C motif chemokine receptor 4 antagonist currently undergoing Phase 2 clinical trials, both as a monotherapy and in combination with pembrolizumab, for various tumor types. Additionally, RAPT's lead inflammation drug candidate, RPT193, aims to selectively inhibit the migration of type 2 T helper cells into allergically inflamed tissues. The company is also exploring other potential targets, including general control nonderepressible 2 and hematopoietic progenitor kinase 1, which are in the discovery phase. Founded in 2015, RAPT Therapeutics was previously known as FLX Bio, Inc. before its name change in May 2019.

Polder Housewares

Acquisition in 2016
Polder Housewares designs, markets, and distributes houseware products to its clients.

Alector

Series D in 2016
Alector, Inc. is a clinical stage biopharmaceutical company focused on developing therapies for neurodegenerative diseases, including Alzheimer's and frontotemporal dementia. The company's lead product, AL001, is a humanized recombinant monoclonal antibody currently in phase II clinical trials for frontotemporal dementia. Additionally, AL101 is in phase I clinical trials for various neurodegenerative diseases, while AL002 and AL003 are undergoing phase 1b trials specifically for Alzheimer's disease. Alector is leveraging advancements in antibody technology, neuroimmunology, and human genetics to create innovative therapeutics. The company maintains a collaboration with Adimab, LLC, which aids in the discovery and optimization of antibody therapeutics. Alector has a pipeline of ten programs in the research and development stage and aims to advance several candidates through pre-clinical development within the next two years. Founded in 2013, Alector is headquartered in South San Francisco, California.
Constellation Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company based in Cambridge, Massachusetts, focused on developing therapeutics aimed at addressing significant unmet medical needs in cancer treatment, particularly those related to abnormal gene expression and drug resistance. The company's lead product candidates include CPI-0610, currently undergoing Phase II clinical trials for myelofibrosis in combination with ruxolitinib, and CPI-1205, which is in Phase Ib/II trials for metastatic castration-resistant prostate cancer alongside androgen receptor signaling inhibitors. Additionally, Constellation is developing CPI-0209, which is in the dose escalation phase of a Phase I/II clinical trial for solid tumors. Founded in 2008, the company was previously known as Epigenetix, Inc. and has established itself as a pioneer in the emerging field of epigenetics, which focuses on selective regulators of epigenetic function crucial for gene expression control.

ORIC Pharmaceuticals

Series B in 2015
ORIC Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing therapies to overcome resistance in cancer treatment. Founded in 2014 and based in South San Francisco, California, the company is advancing several product candidates, including ORIC-101, a small molecule antagonist of the glucocorticoid receptor associated with resistance to various cancer therapies in solid tumors. Another key candidate, ORIC-533, is an orally bioavailable small molecule inhibitor of CD73, which plays a significant role in resistance to chemotherapy and immunotherapy regimens. In addition to these, ORIC is working on multiple precision medicines aimed at addressing other cancer resistance mechanisms. The company's founders, Charles Sawyers and Scott Lowe, are recognized for their contributions to identifying novel cancer targets that have led to innovative treatment options.

JD Beauty

Acquisition in 2015
JD Beauty Group is the perfect company to ensure that you are on the top of your beauty products game. Their product quality, selection, diversity, and prices are the best in the industry. They are commited to using only the best materials in concert with the finest craftsmanship.

Alector

Series C in 2015
Alector, Inc. is a clinical stage biopharmaceutical company focused on developing therapies for neurodegenerative diseases, including Alzheimer's and frontotemporal dementia. The company's lead product, AL001, is a humanized recombinant monoclonal antibody currently in phase II clinical trials for frontotemporal dementia. Additionally, AL101 is in phase I clinical trials for various neurodegenerative diseases, while AL002 and AL003 are undergoing phase 1b trials specifically for Alzheimer's disease. Alector is leveraging advancements in antibody technology, neuroimmunology, and human genetics to create innovative therapeutics. The company maintains a collaboration with Adimab, LLC, which aids in the discovery and optimization of antibody therapeutics. Alector has a pipeline of ten programs in the research and development stage and aims to advance several candidates through pre-clinical development within the next two years. Founded in 2013, Alector is headquartered in South San Francisco, California.

ThermoLift

Venture Round in 2015
ThermoLift, Inc. specializes in the development and manufacturing of innovative air conditioning and heat pump systems for both heating and cooling, as well as hot water applications. Established in 2012 and located in Stony Brook, New York, the company targets both residential and commercial markets. ThermoLift is focused on creating a transformative thermally driven heat pump that integrates heating, cooling, and hot water functions into a single device. This technology aims to significantly reduce energy consumption for space conditioning by up to 50%, reflecting the company's commitment to energy efficiency and sustainability.

SynchroPET

Debt Financing in 2015
SynchroPET Inc. specializes in the development of innovative Positron Emission Tomography (PET) imaging systems for both medical research and clinical applications. Founded in 2013 and based in Stony Brook, New York, the company offers a range of products including PET/MRI systems for comprehensive preclinical research, a portable Mini-PET device for laboratory mobility, and the RatCAP, which allows for unobstructed animal movement during imaging. Additionally, the Wrist PET Detector is designed for non-invasive clinical use. SynchroPET's technologies aim to enhance diagnostic accuracy and treatment efficacy for diseases such as cancer, Alzheimer's, and Parkinson's by providing improved resolution and quantitative data, thus facilitating personalized medical treatments and accelerating research potential.

Codagenix

Series A in 2015
Codagenix, Inc. is a biotechnology company based in Farmingdale, New York, focused on developing live-attenuated viral vaccines for various diseases, including influenza, dengue, respiratory syncytial virus, and polio. The company utilizes its proprietary Synthetic Attenuated Virus Engineering (SAVE) technology, which employs computer-based rational design to construct viral genomes, allowing for the creation of innovative vaccine strains. In addition to human vaccines, Codagenix also provides agricultural and companion animal vaccines. The company has also been engaged in the development of a COVID-19 vaccine, showcasing its commitment to addressing current health challenges. Codagenix was incorporated in 2009 and emphasizes the use of synthetic biology in its vaccine development processes.

NGM Biopharmaceuticals

Series D in 2015
NGM Biopharmaceuticals is a clinical-stage biopharmaceutical company focused on discovering and developing innovative therapeutics for various diseases, including cardio-metabolic, liver, oncologic, and ophthalmic conditions. The company is advancing several product candidates, such as Aldafermin, currently in Phase 2b trials for non-alcoholic steatohepatitis (NASH), and NGM313, an antibody in Phase 1b trials aimed at treating type 2 diabetes and NASH. Other notable candidates include NGM395 for metabolic syndrome, NGM120 targeting cancer anorexia/cachexia syndrome, NGM217 to enhance insulin production in diabetes patients, and NGM621 for addressing dry age-related macular degeneration. Founded in 2007 and headquartered in South San Francisco, NGM Biopharmaceuticals is committed to leveraging insights from human clinical and genetic studies to develop transformative therapies, particularly focusing on the gastrointestinal endocrine system and its role in metabolic diseases. The company collaborates with Merck Sharp & Dohme Corp for research and product development initiatives.

Codagenix

Grant in 2014
Codagenix, Inc. is a biotechnology company based in Farmingdale, New York, focused on developing live-attenuated viral vaccines for various diseases, including influenza, dengue, respiratory syncytial virus, and polio. The company utilizes its proprietary Synthetic Attenuated Virus Engineering (SAVE) technology, which employs computer-based rational design to construct viral genomes, allowing for the creation of innovative vaccine strains. In addition to human vaccines, Codagenix also provides agricultural and companion animal vaccines. The company has also been engaged in the development of a COVID-19 vaccine, showcasing its commitment to addressing current health challenges. Codagenix was incorporated in 2009 and emphasizes the use of synthetic biology in its vaccine development processes.

PlayMonster

Acquisition in 2014
PlayMonster is a leading designer, manufacturer and marketer of games, children’s puzzles, preschool toys, creative activities and teaching tools, with focus on innovation and growth of brands and categories.

Immune Design

Series C in 2013
Immune Design Corp. (IDC) uses breakthrough technology to develop safe and effective vaccines and therapeutics, with emphasis on the prevention and treatment of infectious disease. This goal is being achieved through dedicated research aimed towards a greater understanding of the immune system, and by developing a new generation of immune-based products for the pharmaceutical industry. IDC is passionate about its mission to alleviate human suffering and pursues this goal with high energy and an unsurpassed standard of excellence

SetPoint Medical

Series C in 2013
SetPoint Medical Corporation is a clinical-stage bioelectronic medicine company based in Valencia, California, focused on developing implantable neuromodulation devices for treating chronic inflammatory diseases, including rheumatoid arthritis and Crohn's Disease. The company leverages the Inflammatory Reflex, a natural mechanism that allows the central nervous system to regulate the immune system, which has been extensively studied and documented in scientific literature. SetPoint's proprietary microregulator aims to enhance this reflex through vagus nerve stimulation, offering an alternative treatment option that provides systemic anti-inflammatory effects. The devices are designed to supplement the body's natural responses and are expected to deliver comparable anti-inflammatory potency to leading medications, while potentially offering improved safety and lower costs. Currently, SetPoint is conducting human trials for its technology at multiple centers in Europe.

NGM Biopharmaceuticals

Series C in 2013
NGM Biopharmaceuticals is a clinical-stage biopharmaceutical company focused on discovering and developing innovative therapeutics for various diseases, including cardio-metabolic, liver, oncologic, and ophthalmic conditions. The company is advancing several product candidates, such as Aldafermin, currently in Phase 2b trials for non-alcoholic steatohepatitis (NASH), and NGM313, an antibody in Phase 1b trials aimed at treating type 2 diabetes and NASH. Other notable candidates include NGM395 for metabolic syndrome, NGM120 targeting cancer anorexia/cachexia syndrome, NGM217 to enhance insulin production in diabetes patients, and NGM621 for addressing dry age-related macular degeneration. Founded in 2007 and headquartered in South San Francisco, NGM Biopharmaceuticals is committed to leveraging insights from human clinical and genetic studies to develop transformative therapies, particularly focusing on the gastrointestinal endocrine system and its role in metabolic diseases. The company collaborates with Merck Sharp & Dohme Corp for research and product development initiatives.

Aragon Pharmaceuticals

Series C in 2012
Aragon Pharmaceuticals is a discovery-stage small molecule company dedicated to developing therapeutics for hormone-resistant cancers, particularly focusing on prostate and breast cancer. The company specializes in anti-endocrine therapies that target the biology of these cancers. Its research emphasizes nuclear receptor biology, medicinal chemistry, and drug discovery, with the goal of identifying and developing selective androgen receptor degraders for prostate cancer and selective estrogen receptor degraders for estrogen-sensitive breast cancer.

Celmatix

Series A in 2012
Celmatix is a preclinical-stage women’s health biotech focused uniquely on ovarian biology. With a lead program in ovarian senescence and collaborations in PCOS and non-hormonal contraception with industry leaders, Celmatix is addressing areas of high unmet need by developing the next generation of interventions and pioneering advancements in ovarian health.

Celmatix

Series A in 2011
Celmatix is a preclinical-stage women’s health biotech focused uniquely on ovarian biology. With a lead program in ovarian senescence and collaborations in PCOS and non-hormonal contraception with industry leaders, Celmatix is addressing areas of high unmet need by developing the next generation of interventions and pioneering advancements in ovarian health.

Passport Systems

Series C in 2007
Passport Systems Inc. develops advanced inspection and detection systems aimed at enhancing security in response to global threats. Founded in 2002 and based in Billerica, Massachusetts, the company specializes in active and passive solutions for automatically detecting concealed threats and contraband. Its product lineup includes SmartScan 3D, a fixed cargo scanner designed for the automated clearance of non-threat cargo and vehicles, as well as the detection of complex threats and heavily shielded nuclear materials. Additionally, SmartShield is a networked radiation detection system that helps identify and mitigate potential radiological threats. Passport Systems’ technologies are deployed at air and sea ports, border crossings, and other critical supply chain points, supporting national and international security efforts by ensuring the safe inspection of cargo, validating manifests, and monitoring for radiological dangers.

Neopolitan Networks

Series A in 2007
Neopolitan Networks, headquartered in Palo Alto, California, serves a broad clientele of small, medium-sized, and large organizations with scalable, flexible, robust networking solutions. They provide organizations with transport, including end-to-end private network solutions, Internet connectivity and robust points-of-presence in our data centers that capitalize on advances in fiber optic and wireless technologies to increase network performance and coverage.

Pionetics

Series C in 2007
Pionetics Corporation specializes in manufacturing innovative water treatment products designed to produce safe and great-tasting drinking water while minimizing wastewater compared to traditional systems. Founded in 1995 and headquartered in San Carlos, California, the company offers a range of products, including water filters, drinking water systems, and water coolers, which cater to household, commercial, and industrial applications. Pionetics also provides installation services and rental options for its water treatment systems. Its products are distributed through authorized dealers both domestically and internationally. The company operates as a subsidiary of Rayne Corporation and is supported by financial backing from Kline Hawkes & Co, NGEN Partners, and Unilever Technology Ventures Fund.

Passport Systems

Series B in 2006
Passport Systems Inc. develops advanced inspection and detection systems aimed at enhancing security in response to global threats. Founded in 2002 and based in Billerica, Massachusetts, the company specializes in active and passive solutions for automatically detecting concealed threats and contraband. Its product lineup includes SmartScan 3D, a fixed cargo scanner designed for the automated clearance of non-threat cargo and vehicles, as well as the detection of complex threats and heavily shielded nuclear materials. Additionally, SmartShield is a networked radiation detection system that helps identify and mitigate potential radiological threats. Passport Systems’ technologies are deployed at air and sea ports, border crossings, and other critical supply chain points, supporting national and international security efforts by ensuring the safe inspection of cargo, validating manifests, and monitoring for radiological dangers.

Game Trust

Series B in 2005
Game Trust, Inc. specializes in providing infrastructure for community and commerce applications in the online gaming and entertainment sector. Founded in 2002 and headquartered in New York, the company has developed the Game Frame platform, which caters to the casual gaming market. This platform is licensed by website operators and game developers, enabling them to enhance user experiences by incorporating online entertainment, community features, and commerce functionalities into both new and existing games. Game Trust operates in the United States and Europe, serving a diverse clientele of game distributors and developers. As of October 2007, it functions as a subsidiary of RealNetworks, Inc.

Sensicore

Series C in 2005
Sensicore, Inc. develops smart sensor systems and sensor networks that automate water testing, data collection, and analysis for drinking and industrial applications. It offers WaterPOINT, a handheld screening tool and water tester that provides a profile of various chemistry measurements, allowing users to conduct various tests at sites, as well as allows municipalities to manage resources; and WaterNOW, a Web-based data visualization, analysis, and decision support system that enable users to manage water system and data collected by WaterPOINT and other sources. The company also provides sensor kits and bundles, which include disinfection and disinfection/DPD chlorine drinking water test kits, and basic water test kits; and colorimetric test kits, including aluminum, bromine, chloride, copper, cyanide, fluoride, iron, manganese, molybdate, nitrate, nitrite, ortho-phosphate, silica, sulfate, sulfide, and zinc vacuum ampoules. In addition, the company offers accessories, such as portable thermal printers, communications cables, power inverters, and power supply products. It offers products for measuring and monitoring water quality, including incoming water quality and boiler feed monitoring; cooling tower monitoring and process control; filtration system performance monitoring; cleaning and rinse control system monitoring; product testing and control; and food and beverage applications. The company was founded in 2000 and is based in Ann Arbor, Michigan. As of March 31, 2008, Sensicore, Inc. operates as a subsidiary of GE Analytical Instruments, Inc.
Arginox Pharmaceuticals is a biopharmaceutical company engaged in the discovery and development of drugs for cardiovascular pathologies. It offers Tilarginine Acetate Injection that inhibits the production of nitric oxide, which is used for treatment of cardiogenic shocks. Arginox Pharmaceuticals is based in Redwood City, California.

Roche NimbleGen

Series F in 2004
Roche NimbleGen specializes in providing a range of products and services for the life science research market, particularly in DNA sequencing and microarray technology. The company offers the SeqCap EZ system, which allows for exome enrichment in a single test tube, along with various design options and reagents to facilitate workflow. Additionally, Roche NimbleGen has developed the SeqCap Epi system for DNA methylation assessment at single-base resolution, and it supplies preparation and adapter kits for library construction. Their proprietary Maskless Array Synthesis technology enables the creation of custom high-density DNA arrays, enhancing the quality and data yield of sequencing efforts. The company also provides a suite of DNA microarray products for applications such as comparative genomic hybridization and gene expression analysis, alongside technical support services. Founded in 1999 and based in Madison, Wisconsin, Roche NimbleGen operates as a subsidiary of Roche Holding AG.
Arginox Pharmaceuticals is a biopharmaceutical company engaged in the discovery and development of drugs for cardiovascular pathologies. It offers Tilarginine Acetate Injection that inhibits the production of nitric oxide, which is used for treatment of cardiogenic shocks. Arginox Pharmaceuticals is based in Redwood City, California.

Game Trust

Series A in 2003
Game Trust, Inc. specializes in providing infrastructure for community and commerce applications in the online gaming and entertainment sector. Founded in 2002 and headquartered in New York, the company has developed the Game Frame platform, which caters to the casual gaming market. This platform is licensed by website operators and game developers, enabling them to enhance user experiences by incorporating online entertainment, community features, and commerce functionalities into both new and existing games. Game Trust operates in the United States and Europe, serving a diverse clientele of game distributors and developers. As of October 2007, it functions as a subsidiary of RealNetworks, Inc.

netomat

Series B in 2003
netomat, Inc. develops Websites, applications, and social media services that work across desktop, tablet, and mobile devices. It offers mobile solutions, such as mobile Website or responsive design, mobile apps, and location-based services; and Web solutions, which include Websites and microsites Web apps, HTML5/CSS3, HTML email and responsive email, and Web forms and data collection solutions. The company also provides social media solutions, including integration with social media sites and networks, social Web apps and widgets, and social media analytics; and contests, sweepstakes, quizzes, and polls. In addition, it offers creative services, such as Web UI/UX design, mobile UI/UX design, and social campaigns and marketing programs; managed services, which include cloud hosting services, search engine optimization, mobile and Web analytics, Ad integration, and e-commerce integration services; optimization solutions for touch-screen devices; and netomat Mobility Server, which enables organizations to publish Websites across various mobile device models. Further, the company provides netomat MediaHub that enables enterprises to acquire, transform, manage, and stream videos across mobile and desktop devices. It serves tourism organizations, sports leagues, gaming companies, NFL teams, record labels, and law firms in the United States and internationally. netomat, Inc. was founded in 2001 and is based in New York, New York.

comScore

Series E in 2003
comScore, Inc. is an information and analytics company that specializes in measuring audiences, consumer behavior, and advertising across various media platforms globally. The company provides a range of products and services, including Media Metrix and Mobile Metrix for website and app measurement, Video Metrix for digital video consumption metrics, and Plan Metrix for insights into consumer lifestyles. Additionally, it offers validated Campaign Essentials, which ensure the visibility and safety of digital ad impressions, and Campaign Ratings for comprehensive campaign evaluation across media. Its services extend to TV Essentials, StationView Essentials, and OnDemand Essentials, integrating traditional TV viewership with digital data. Furthermore, comScore delivers analytics for the film industry, capturing real-time box office results and audience insights. Founded in 1999 and headquartered in Reston, Virginia, comScore serves over 3,200 clients across more than 75 countries, focusing on delivering precise, cross-platform measurement solutions for the evolving media landscape.

Sensicore

Series B in 2003
Sensicore, Inc. develops smart sensor systems and sensor networks that automate water testing, data collection, and analysis for drinking and industrial applications. It offers WaterPOINT, a handheld screening tool and water tester that provides a profile of various chemistry measurements, allowing users to conduct various tests at sites, as well as allows municipalities to manage resources; and WaterNOW, a Web-based data visualization, analysis, and decision support system that enable users to manage water system and data collected by WaterPOINT and other sources. The company also provides sensor kits and bundles, which include disinfection and disinfection/DPD chlorine drinking water test kits, and basic water test kits; and colorimetric test kits, including aluminum, bromine, chloride, copper, cyanide, fluoride, iron, manganese, molybdate, nitrate, nitrite, ortho-phosphate, silica, sulfate, sulfide, and zinc vacuum ampoules. In addition, the company offers accessories, such as portable thermal printers, communications cables, power inverters, and power supply products. It offers products for measuring and monitoring water quality, including incoming water quality and boiler feed monitoring; cooling tower monitoring and process control; filtration system performance monitoring; cleaning and rinse control system monitoring; product testing and control; and food and beverage applications. The company was founded in 2000 and is based in Ann Arbor, Michigan. As of March 31, 2008, Sensicore, Inc. operates as a subsidiary of GE Analytical Instruments, Inc.

Pionetics

Series B in 2003
Pionetics Corporation specializes in manufacturing innovative water treatment products designed to produce safe and great-tasting drinking water while minimizing wastewater compared to traditional systems. Founded in 1995 and headquartered in San Carlos, California, the company offers a range of products, including water filters, drinking water systems, and water coolers, which cater to household, commercial, and industrial applications. Pionetics also provides installation services and rental options for its water treatment systems. Its products are distributed through authorized dealers both domestically and internationally. The company operates as a subsidiary of Rayne Corporation and is supported by financial backing from Kline Hawkes & Co, NGEN Partners, and Unilever Technology Ventures Fund.

comScore

Series D in 2002
comScore, Inc. is an information and analytics company that specializes in measuring audiences, consumer behavior, and advertising across various media platforms globally. The company provides a range of products and services, including Media Metrix and Mobile Metrix for website and app measurement, Video Metrix for digital video consumption metrics, and Plan Metrix for insights into consumer lifestyles. Additionally, it offers validated Campaign Essentials, which ensure the visibility and safety of digital ad impressions, and Campaign Ratings for comprehensive campaign evaluation across media. Its services extend to TV Essentials, StationView Essentials, and OnDemand Essentials, integrating traditional TV viewership with digital data. Furthermore, comScore delivers analytics for the film industry, capturing real-time box office results and audience insights. Founded in 1999 and headquartered in Reston, Virginia, comScore serves over 3,200 clients across more than 75 countries, focusing on delivering precise, cross-platform measurement solutions for the evolving media landscape.

TeraLogic

Venture Round in 2001
TeraLogic designs integrated circuits, software and platforms for digital TV.
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