Cardiovate, Inc. is a medical technology company based in San Antonio, Texas, that specializes in developing products for tissue regeneration and repair. Founded in 2012, the company focuses on innovative solutions for vascular health, including its flagship product, NeoVessel, a vascular graft designed to promote the regeneration and repair of vascular tissues. Through its commitment to advancing medical technology, Cardiovate aims to address significant healthcare challenges in the field of tissue engineering.
Aerin Medical Inc. is a health technology company based in Sunnyvale, California, focused on developing non-invasive treatment solutions for nasal breathing disorders. Founded in 2011, the company specializes in therapeutic devices that utilize low-power radiofrequency energy to remodel nasal soft tissues, effectively addressing the underlying causes of conditions such as nasal obstruction and chronic rhinitis. Aerin Medical offers procedures and devices, including the VivAer procedure and the RhinAer procedure, along with their corresponding styluses, which allow ENT physicians to treat nasal airway conditions in an office setting under local anesthesia. These innovative solutions aim to improve patient outcomes by providing safe, quick, and effective relief from chronic nasal symptoms while minimizing downtime.
Roxy’s Remedies
Series A in 2016
Roxy’s Remedies provides natural grooming products for dogs with canine atopic dermatitis. Roxy’s Remedies' product line is formulated with sustainably cultivated, pharmaceutical-grade East Indian Sandalwood Oil (EISO) produced by TFS Corporation Ltd. EISO is a natural, calming ingredient that has been used as a traditional skin healing agent and is being developed by Santalis as a prescription drug for human skin conditions.
StemBioSys, Inc. is a biomedical company based in San Antonio, Texas, specializing in the isolation, expansion, and delivery of specialized adult stem cells for various applications, including research, diagnostics, and clinical use. Founded in 2010, the company focuses on developing proprietary stem cell technologies that replicate the natural three-dimensional environment of stem cells, enhancing their growth and functionality. Its flagship product, BM-HPME, serves as an advanced stem cell culture system. StemBioSys aims to address significant health challenges such as diabetes, Alzheimer's, Parkinson's disease, inflammatory disorders, and osteoarthritis by collaborating with other entities to advance and license its stem cell technologies for therapeutic purposes. The company is committed to contributing to the field of regenerative medicine in a rapidly expanding global market.
Xenex is a company focused on reducing healthcare-associated infections (HAIs) through its advanced ultraviolet disinfection technology. Founded in 2009 and based in San Antonio, Texas, Xenex has developed a portable device that utilizes pulsed xenon UV light to eliminate harmful microorganisms in hospital environments. Since launching its disinfection system in June 2010, the company’s devices have been integrated into infection control protocols in nearly three hundred hospitals across the United States. By effectively reducing the bacterial load that contributes to HAIs, Xenex aims to enhance patient safety and safeguard healthcare staff, ultimately striving to save lives and alleviate suffering in healthcare settings.
DNAtrix, Inc. is a clinical stage biotechnology company based in Houston, Texas, specializing in virus-driven immunotherapies for cancer treatment. The company develops modified viruses designed to selectively target and kill cancer cells, with its lead product, DNX-2401, focused on glioblastoma, an aggressive and currently incurable brain tumor. This oncolytic immunotherapy has shown promising early results, having been administered to over 35 patients. In addition to DNX-2401, DNAtrix is advancing other therapies, including DNX-2440 and DNX-2450 for solid tumors, and MYX-135 for hematological malignancies. The company aims to expand its platform technology to address a broader range of cancers, including brain metastases, ovarian, and pancreatic cancer. DNAtrix has formed a strategic partnership with Valo Therapeutics to enhance its research and development efforts.
Bluegrass Vascular Technologies, Inc. is a medical technology company focused on developing and commercializing innovative devices to improve vascular access procedures for patients with obstructed central venous systems. Its flagship product, the Surfacer Inside-Out Access Catheter System, enables physicians to achieve central venous access by guiding a wire through the femoral vein to exit at the jugular or subclavian vein. This system is particularly beneficial for patients suffering from venous occlusive disease, with over 400 successful procedures conducted to date. Founded in 2010 and based in San Antonio, Texas, Bluegrass Vascular Technologies serves both domestic and international markets.
Xenex is a company focused on reducing healthcare-associated infections (HAIs) through its advanced ultraviolet disinfection technology. Founded in 2009 and based in San Antonio, Texas, Xenex has developed a portable device that utilizes pulsed xenon UV light to eliminate harmful microorganisms in hospital environments. Since launching its disinfection system in June 2010, the company’s devices have been integrated into infection control protocols in nearly three hundred hospitals across the United States. By effectively reducing the bacterial load that contributes to HAIs, Xenex aims to enhance patient safety and safeguard healthcare staff, ultimately striving to save lives and alleviate suffering in healthcare settings.
Private Equity Round in 2013
ViroXis Corporation is a bio-pharmaceutical company based in San Antonio, Texas, specializing in the development and commercialization of botanical pharmaceuticals derived from East Indian sandalwood oil. The company has developed a proprietary botanical ointment that utilizes a defined mixture from Santalum album, aimed at treating human papillomavirus (HPV) infections of the skin in both children and adults. Additionally, ViroXis is working on an EISO cream to address other HPV-related conditions. The company has established strategic partnerships with TFS Corporation Ltd. and DPT Laboratories, Inc. Founded in 2006, ViroXis operates as a subsidiary of TFS Corporation Ltd. as of 2015.
Bi02 Medical, Inc. designs, develops, manufactures, and commercializes medical devices for clinical needs. The company offers Angel Catheter, an inferior vena cava (IVC) filter for the protection of prophylactic pulmonary embolism, and access to the central venous system in critically ill patients. It sells its products through distribution partners worldwide. Bi02 Medical, Inc. was formerly known as BiO2 Medical Inc. The company was founded in 2006 and is based in San Antonio, Texas with a research and development, and manufacturing facility in Golden, Colorado.
Vidacare Corporation, a medical device company, engages in the development, manufacture, and marketing of intraosseous access devices for diagnostic, monitoring, and therapeutic applications. The company provides EZ-IO Product System, which is designed to provide controlled vascular access through the intraosseous route to patients in emergent situations when vascular access is challenging and impossible. It also offers EZ-IO power driver, which is designed to penetrate the intraosseous space by drilling through the bone with a hollow needle and integrated stylet that doubles as the forward cutting bit to secure its correct placement; and EZ-IO Vascular Access Pack, a kit developed for emergency medical specialists to provide access to IV and IO devices to gain vascular access. In addition, the company provides a suite of hematology/oncology products, including a power driver and needle sets for bone marrow aspiration and biopsy; and OnControl, a bone marrow system for clinicians to perform bone marrow aspiration and biopsy procedures. Its products are used in pre-hospital, emergency, crash cart, and rapid response applications, as well as in military and homeland security industries. Vidacare Corporation was founded in 2001 and is headquartered in San Antonio, Texas.
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