MB Growth Partners

MB Venture Partners is a Memphis, Tennessee venture capital firm that provides equity capital and strategic direction to life sciences companies. The Firm invests in medical device and biotechnology companies at all stages of development. Their Firm is especially interested in product solutions for musculoskeletal diseases, and their partners benefit from their deep experience and relationships in this area of investment.

Mike Sherman

Partner

SS

Stephen Snowdy

Partner

Gary Stevenson

Managing Partner

JD

James D. Witherington

Member of Financial Advisory Board

92 past transactions

AxioMed LLC

Series D in 2013
AxioMed LLC designs and develops a disc replacement device that facilitates neck pain relief and restores normal spinal functions for patients with degenerative disc disease. AxioMed LLC was formerly known as AxioMed Spine Corporation and changed its name to AxioMed LLC in November 2014. The company was founded in 2001 and is based in Malden, Massachusetts.

ECOSURG

Seed Round in 2013
EcoSurg™ (pronounced eek-oh-surj) is a developer of environmentally-friendly surgical supplies that is dedicated to reducing the carbon footprint of the surgical suite. Their flagship product is the EcoSurg™ line of Patient Positioners. Disposable patient positioners are used in over 20 Million surgical procedures per year in the United States alone. These foam shapes are used to properly position patients in a variety of positions, ensuring safety, comfort, and adequate access to the surgical site. When disposed of, however, these products are harmful to the environment as they are made from materials that consist largely of petroleum-based derivatives. These compounds and the other hazardous byproducts from their production are not only harmful to the environment, but also incur higher handling and disposal costs that are inevitably passed on to the Customer.
International Coding Technologies, Inc., an inventory control and tracking technology firm, designs, develops, and implements radio frequency identification (RFID) and barcode productivity solutions for the construction industry in the United States.

Innometrix

Seed Round in 2014
Innometrix, Inc. develops a technology that produces a biomechanical snapshot of the female pelvic floor that will give physicians better data prior to surgery. The company is based in Memphis, Tennessee.

iScreen Vision

Series B in 2013
iScreen Vision, Inc. develops a screening equipment using a technology known as photoscreening to screen children’s vision for vision problems. The Company provides a fast, easy, and portable pediatric vision screening solution for infants and pre-school and school-age children. The company was formerly known as iScreen, LLC and changed its name in April 2009. iScreen Vision, Inc. was incorporated in 2009 and is based in Cordova, Tennessee.

Spinal Restoration, Inc.

Venture Round in 2012
Spinal Restoration was formed to identify and develop new, early intervention, minimally invasive therapies for the treatment of chronic low back pain. The company’s first endeavor is the Biostat® System, a proprietary resorbable biologic compound and delivery system for the treatment of chronic disc pain. The new treatment specifically targets discogenic pain, which represents the single largest population of patients—an estimated four million adults—who suffer from chronic low back pain annually.

Lineus Medical

Seed Round in 2016
Lineus Medical offers medical device designed to prevent IV dislodgement and other IV mechanical complications. Its SafeBreak Vascular device utilizes a patented break-away technology to create a separation in the IV tubing.

CrossRoads Extremity Systems, LLC

Venture Round in 2014
CrossRoads Extremity Systems is a medical device manufacturing company that specializes in engineering foot and ankle implant systems. Using technology and materials, like high compression nitinol, our products are optimal for surgery. It was founded in 2014 and headquartered in Memphis, Tennessee.

GTx

Series E in 2003
GTx, Inc. is a company of pioneering and driven individuals who are delivering better medicines with new science through established pathways.

Spine Wave

Series F in 2016
Spine Wave, Inc. manufactures and markets medical equipment for the treatment of spinal disorders. It offers expandable PEEK spacers and expandable interbody devices for posterior surgery; pivoting spacer systems; lateral spacer systems, XDL expandable devices, and lateral access systems for lateral stabilization; Leva PX, an expandable interbody device for the treatment of spinal disorders; GraftMag Graft Delivery System to deliver large amounts of bone graft; and fixation products, such as spine systems for treating degeneration, deformity, tumor, and trauma of the thoracolumbar spine, as well as adjacent level systems. The company also offers anterior cervical plate systems that provide stabilization as an adjunct to spinal fusion from C2-C7 through anterior screw fixation; and cervical spacer systems to treat degenerative disc disease from C2-T1. It offers its products through distributors. Spine Wave, Inc. was founded in 2001 and is based in Shelton, Connecticut.

Tidal Wave Technology

Seed Round in 2012
Tidal Wave Technology manufactures a device to achieve a circumferential ablation of the nerves that surround the renal artery. It allows for renal denervation without placing any ablative elements within the renal artery. The company was founded in 2011 and is based in Memphis, Tennessee.

Mobilizer

Seed Round in 2013
Mobilizer Inc., a graduate of the ZeroTo510 medical device startup accelerator, has created a six-wheeled holster for medical equipment in order to make medical ambulation easier and faster.

Hapten Sciences

Seed Round in 2012
Hapten Sciences, Inc. operates as a biopharmaceutical company. It identifies and develops early-stage products, such as PDC-APB that acts as a vaccine to prevent contact dermatitis caused by exposure to urushiol oil in poison ivy, poison oak, or poison sumac plants. The company was incorporated in 2010 and is based in Memphis, Tennessee.

Mobilizer

Seed Round in 2013
Mobilizer Inc., a graduate of the ZeroTo510 medical device startup accelerator, has created a six-wheeled holster for medical equipment in order to make medical ambulation easier and faster.

Better Walk Inc.

Series A in 2015
The company was built on the principle that even age old technologies require innovation, and that mindset has proven to be one of the main pillars of their culture as they've grown. Better Walk was accepted into the second class of the Zero To 510 accelerator in Memphis, TN where it raised its early venture funding. In late 2014, the company moved its headquarters to Atlanta, GA, and focused on developing the Better Walk crutch and is currently preparing for production and a product launch that will begin in early 2015.

Visioneering Technologies, Inc.

Venture Round in 2009
Visioneering Technologies, Inc., a medical device company, engages in the design, manufacture, sale, and distribution of contact lenses. The company offers NaturalVue, a contact lense for adults with presbyopia and children with myopia. It operates in the United States, Australia, New Zealand, Europe, Hong Kong, and Singapore. The company was founded in 2008 and is headquartered in Alpharetta, Georgia.

HandMinder

Seed Round in 2012
Currently, there are 7M stroke survivors in the US. Additionally, there are more than 795K new or recurrent stroke survivors every year. Americans pay $73.7B annually for stroke-related medical costs and disability. Approximately 60% of them suffer from hand dysfunction. Current treatments and devices for hand dysfunction focus primarily on muscle rehabilitation, with the patient taking a passive role. Further, these interventions are expensive and inconvenient. Current treatments are inadequate, as recent studies show that active engagement of the brain during hand rehabilitation improves the amount of hand movement by 2x over traditional treatments and further improves the quality of hand movement by 2.5x over these traditional methods. Based on this research, we created the HandMinder portable hand rehabilitation device which employs patent-pending vibration-guided brain engagement technology that strengthens the neural connections between the hand and brain, producing marked improvement in patients’ hand function. Further, HandMinder is affordable, convenient, and used in clinical settings and at home.

Urova Medical Inc.

Seed Round in 2012
Urova Medical was founded in Memphis, TN with the goal of providing a novel solution to cure stress urinary incontinence safely, effectively, and conveniently. Urova Medical’s technology was developed by an undergraduate team of talented biomedical engineers at Johns Hopkins University. The implant was designed extensively under the mentorship of physicians from the Johns Hopkins Hospital, the number one urological center in the US. Urova Medical has been part of the Zeroto510 Accelerator program sponsored by Innova Fund and MB Ventures, both venture capital firms based in Memphis

Better Walk Inc.

Seed Round in 2013
The company was built on the principle that even age old technologies require innovation, and that mindset has proven to be one of the main pillars of their culture as they've grown. Better Walk was accepted into the second class of the Zero To 510 accelerator in Memphis, TN where it raised its early venture funding. In late 2014, the company moved its headquarters to Atlanta, GA, and focused on developing the Better Walk crutch and is currently preparing for production and a product launch that will begin in early 2015.

Calosyn Pharma

Seed Round in 2009
CaloSyn Pharma, Inc., a biopharmaceutical company, develops intra-articular therapeutics for osteoarthritis. It develops drugs, which is known as calcium channel blockers for osteoarthritis. These drugs used in the treatment of heart and vascular diseases. Its therapeutic approach is based on combinations of ion channel modulators, which block the synthesis of the enzymes responsible for cartilage destruction. The company was founded in 2007 and is based in Boston, Massachusetts with additional offices in Shreveport, Louisiana and Atlanta, Georgia.

BioMimetic Therapeutics

Series B in 2003
BioMimetic Therapeutics is a biotechnology company that develops products to help stimulate the body natural tissue regenerative process. The company's products and product candidates include Augment Injectable and Augment Rotator Cuff for several orthopedic and sports medicine indications comprising the treatment of foot and ankle fusions, the stimulation of wrist fracture healing, and the surgical treatment of rotator cuff tears, as well as Augment Tendinopathy Injection for injuries cause of tendon overuse. BioMimetic Therapeutics was founded on 1999 and is headquartered in Franklin, Tennessee.

Ortho Kinematics, Inc.

Venture Round in 2015
Ortho Kinematics is a spine diagnostics company, provides spine motion analysis and diagnostic services. The company provides information to spine clinicians to assist them in diagnosing and treating back and neck pain. Its solution includes KineGraph Vertebral Motion Analyzer, an automated functional diagnostic test for the spine that uses fluoroscopy to capture the spine in motion, producing patient-specific graphs of the kinematics for each vertebral level. The company was founded in 2006 and is based in Austin, Texas.

Better Walk Inc.

Seed Round in 2013
The company was built on the principle that even age old technologies require innovation, and that mindset has proven to be one of the main pillars of their culture as they've grown. Better Walk was accepted into the second class of the Zero To 510 accelerator in Memphis, TN where it raised its early venture funding. In late 2014, the company moved its headquarters to Atlanta, GA, and focused on developing the Better Walk crutch and is currently preparing for production and a product launch that will begin in early 2015.
Restore Medical Solutions is a medical device company focusing on products and techniques that promote SSI reduction, safety, and productivity within healthcare. The company manufactures a sterilization tray system that reduces the risk of infection from contaminated medical instruments. Its modular sterilization tray systems reduce the potential risk of infection from contaminated instruments and enable surgical departments to improve the quality of care while reducing cost. Founded in 2012, Restore Medical Solutions is headquartered in Memphis, Tennessee.

Anulex Technologies

Series D in 2009
Anulex Technologies focus on developing proprietary medical technology to repair and seal the soft tissue of the spine (anulus) for patients undergoing a surgical procedure to remove a herniated disc (discectomy).

Anulex Technologies

Series C in 2006
Anulex Technologies focus on developing proprietary medical technology to repair and seal the soft tissue of the spine (anulus) for patients undergoing a surgical procedure to remove a herniated disc (discectomy).
Veracity Medical Solutions is a contract manufacturing company specializing in the Medical Device Industry. They have capabilities from raw matl to finished, laser marked & packaged products. Additional value added services offered: Design / Development / Prototype / Customs / Specials

CamPlex

Seed Round in 2014
CamPlex is a U.S.-based company that operates in the healthcare industry. The company was founded in 2012 and is headquartered in Germantown, Tennessee.
Blood Monitoring Solutions has developed a system that will allow blood banks to proactively monitor the temperature of blood in order to prevent wastage from ever occurring. Utilizing their proactive, data-driven approach, they will increase patient safety and reduce costs for hospitals worldwide.

KFx Medical

Series B in 2007
KFx® Medical, develops and manufactures innovative soft tissue fixation implants for orthopedic sports medicine surgeons. Our partnerships with the world's leading orthopaedic surgeons motivates us to develop new technology and proven surgical implants, resulting in positive surgical outcomes for the patients.

Ortho Kinematics, Inc.

Series C in 2015
Ortho Kinematics is a spine diagnostics company, provides spine motion analysis and diagnostic services. The company provides information to spine clinicians to assist them in diagnosing and treating back and neck pain. Its solution includes KineGraph Vertebral Motion Analyzer, an automated functional diagnostic test for the spine that uses fluoroscopy to capture the spine in motion, producing patient-specific graphs of the kinematics for each vertebral level. The company was founded in 2006 and is based in Austin, Texas.

S2 Interactive

Seed Round in 2012
S2 Interactive, Inc. is a Delaware C corp. founded by Larry Foster, R.N., in September, 2011. After working as a surgical nurse and spending 26 years in leadership roles within sales, marketing and professional education in the orthopedic & spine industry, Larry was convinced there was an opportunity to teach hospital staff to learn and manage surgical instruments more efficiently and safely. Larry spent five years working with technology experts realizing with the current trends in healthcare there was a clear need to increase hospital staff productivity/efficiency while driving cost savings. Larry’s vision combined with the introduction of user-friendly “hand held” technology platforms (tablets) enabled S2 Interactive to develop Virtual Back Table and Tray Touch software platforms. In September, 2011 additional funding was provided by 2 Memphis based venture capital organizations, Innova & MB Ventures. They are proud to be working with market leading companies in Medical Devices and many of the nation’s most prominent hospitals. Their technology has been used by over 1,000 different users in a variety of surgical specialties including cardiology, orthopedics, spine , general surgery and trauma.
Established in 1999, Salient Surgical Technologies, Inc. is a global, privately held medical technology company that develops and markets advanced energy devices used in surgical procedures. Salient’s first line of products were monopolar electrosurgical devices used for the treatment of liver cancers. Today, the company’s bipolar AQUAMANTYS® System is used across a wide range of surgical procedures including orthopaedic reconstruction, spine surgery, orthopaedic trauma, and surgical oncology. Comprised of a bipolar electrosurgical generator & pump system and a portfolio of handheld disposable device, the AQUAMANTYS system uses patented TRANSCOLLATION® technology to haemostatically seal soft tissue and bone, enabling surgeons to reduce and prevent surgical blood loss. Salient’s products are sold throughout the United States, Europe, and Asia, providing clinical and economic benefits to hospitals, healthcare providers, and patients all over the world. To date, more than 500,000 patients have been treated with TRANSCOLLATION technology.

Tidal Wave Technology

Seed Round in 2014
Tidal Wave Technology manufactures a device to achieve a circumferential ablation of the nerves that surround the renal artery. It allows for renal denervation without placing any ablative elements within the renal artery. The company was founded in 2011 and is based in Memphis, Tennessee.

SurgiLight

Seed Round in 2013
SurgiLight offers a surgical lighting system that provides surgeons with a practical illumination device, enabling them to focus on target areas.

BioNanovations Corporation

Seed Round in 2013
Bell BioNanonostics Corp. focuses on monitoring of bacterial infection. Bell BioNanonostics Corp. is based in the United States.

ECOSURG

Seed Round in 2012
EcoSurg™ (pronounced eek-oh-surj) is a developer of environmentally-friendly surgical supplies that is dedicated to reducing the carbon footprint of the surgical suite. Their flagship product is the EcoSurg™ line of Patient Positioners. Disposable patient positioners are used in over 20 Million surgical procedures per year in the United States alone. These foam shapes are used to properly position patients in a variety of positions, ensuring safety, comfort, and adequate access to the surgical site. When disposed of, however, these products are harmful to the environment as they are made from materials that consist largely of petroleum-based derivatives. These compounds and the other hazardous byproducts from their production are not only harmful to the environment, but also incur higher handling and disposal costs that are inevitably passed on to the Customer.

Spinal Restoration, Inc.

Series C in 2013
Spinal Restoration was formed to identify and develop new, early intervention, minimally invasive therapies for the treatment of chronic low back pain. The company’s first endeavor is the Biostat® System, a proprietary resorbable biologic compound and delivery system for the treatment of chronic disc pain. The new treatment specifically targets discogenic pain, which represents the single largest population of patients—an estimated four million adults—who suffer from chronic low back pain annually.

Tidal Wave Technology

Seed Round in 2012
Tidal Wave Technology manufactures a device to achieve a circumferential ablation of the nerves that surround the renal artery. It allows for renal denervation without placing any ablative elements within the renal artery. The company was founded in 2011 and is based in Memphis, Tennessee.

Focal Point Pharmaceuticals

Seed Round in 2013
Focal Point Pharmaceuticals is a healthcare company focused on pharmaceutical businesses. It was incorporated in 2013 and is based in Memphis, Tennessee, United States.

Zyga Technology, Inc.

Series D in 2014
Zyga Technology is a surgical solutions provider developing & commercializing medical devices for treating spine problems. In addition to the SImmetry Sacroiliac Joint Fusion System, the company is also developing the Glyder Facet Restoration Device. Zyga has put together a team of engineers, marketing personnel, and management with significant experience developing medical devices for the spine industry. Zyga Technology was founded in 2008 and is headquartered in Minnesota, USA.

SweetBio, Inc.

Pre Seed Round in 2015
SweetBio, Inc. researches, develops, and manufactures membranes that reduce complications and infections created by wounds, pressure ulcers, diabetic ulcers, surgical wounds, and abrasions. Its membrane incorporates medical grade Manuka honey for healing and fighting bacteria. SweetBio, Inc. was incorporated in 2015 and is headquartered in Memphis, Tennessee.

Zyga Technology, Inc.

Series C in 2012
Zyga Technology is a surgical solutions provider developing & commercializing medical devices for treating spine problems. In addition to the SImmetry Sacroiliac Joint Fusion System, the company is also developing the Glyder Facet Restoration Device. Zyga has put together a team of engineers, marketing personnel, and management with significant experience developing medical devices for the spine industry. Zyga Technology was founded in 2008 and is headquartered in Minnesota, USA.

Cuff-Protect

Seed Round in 2013
Cuff-Mate skin barriers offer healthcare professionals a cost-effective way to protect their patients, themselves and equipment when taking vital signs.

Hubble Telemedical

Seed Round in 2012
Hubble Telemedical is dedicated to enabling earlier detection of systemic and debilitating diseases that manifest in the retina - the light-sensitive membrane at the back of the eye that transmits visual information to the brain - for more effective treatment and patient care. In addition to eye diseases such as retinopathy, macular degeneration and glaucoma, a range of systemic diseases such cardiovascular and immune diseases can be detected in the retina. Early diagnosis is essential for effective treatment of these diseases. Unfortunately, many at-risk individuals do not receive annual retinal exams due to inconvenience or unavailability. The result is that many individuals go undiagnosed until severe damage has occurred, causing medical complications and increased healthcare costs. They are changing that paradigm. Thanks to their proprietary, award-winning Telemedical Retinal Image Analysis and Diagnosis (TRIAD™) technology, Hubble Telemedical enables screening and diagnosis where and when it is most convenient for the healthcare consumer. They partner with healthcare providers, insurance companies, and employers to bring the power of retinal screening to the consumer. Their services are fully HIPAA-compliant, secure, and easy to use –- and multi-site, peer-reviewed and published clinical studies have demonstrated their ability to dramatically increase annual screening compliance, thereby decreasing overall healthcare costs and, most importantly, improving patients' health. They invite you to contact us to learn more about their services and technology— and how they can work with you to bring the power of retinal image analysis to your organization.

KFx Medical

Series A in 2005
KFx® Medical, develops and manufactures innovative soft tissue fixation implants for orthopedic sports medicine surgeons. Our partnerships with the world's leading orthopaedic surgeons motivates us to develop new technology and proven surgical implants, resulting in positive surgical outcomes for the patients.
Restore Medical Solutions is a medical device company focusing on products and techniques that promote SSI reduction, safety, and productivity within healthcare. The company manufactures a sterilization tray system that reduces the risk of infection from contaminated medical instruments. Its modular sterilization tray systems reduce the potential risk of infection from contaminated instruments and enable surgical departments to improve the quality of care while reducing cost. Founded in 2012, Restore Medical Solutions is headquartered in Memphis, Tennessee.

Lineus Medical

Series B in 2020
Lineus Medical offers medical device designed to prevent IV dislodgement and other IV mechanical complications. Its SafeBreak Vascular device utilizes a patented break-away technology to create a separation in the IV tubing.

Ortho Kinematics, Inc.

Series A in 2010
Ortho Kinematics is a spine diagnostics company, provides spine motion analysis and diagnostic services. The company provides information to spine clinicians to assist them in diagnosing and treating back and neck pain. Its solution includes KineGraph Vertebral Motion Analyzer, an automated functional diagnostic test for the spine that uses fluoroscopy to capture the spine in motion, producing patient-specific graphs of the kinematics for each vertebral level. The company was founded in 2006 and is based in Austin, Texas.

Cayenne Medical

Series B in 2007
Cayenne Medical, Inc. a sports medicine company, provides arthroscopic surgery products. It offers AperFix System that enables the surgeons to perform anterior cruciate ligament (ACL) reconstruction using the hamstring and various soft tissue grafts. The company also provides AperFix Femoral device to restore native knee kinematics; AperFix Tibial device for anatomic reconstruction applications; and iFix Interference Screw System for ACL reconstruction procedure using the bone-patellar tendon-bone and various bone-tendon-bone grafts. In addition, it offers interference screws and shoulder products. Cayenne Medical, Inc. was founded in 2005 and is based in Scottsdale, Arizona.

AIS

Seed Round in 2013
Although it is still relatively new, AIS, having a relationship with other biology-inspired computing models, and computational biology.

Cayenne Medical

Venture Round in 2012
Cayenne Medical, Inc. a sports medicine company, provides arthroscopic surgery products. It offers AperFix System that enables the surgeons to perform anterior cruciate ligament (ACL) reconstruction using the hamstring and various soft tissue grafts. The company also provides AperFix Femoral device to restore native knee kinematics; AperFix Tibial device for anatomic reconstruction applications; and iFix Interference Screw System for ACL reconstruction procedure using the bone-patellar tendon-bone and various bone-tendon-bone grafts. In addition, it offers interference screws and shoulder products. Cayenne Medical, Inc. was founded in 2005 and is based in Scottsdale, Arizona.

Cast21

Seed Round in 2017
Cast21 has designed a light-weight, lattice-structure cast that is breathable and waterproof, eliminating many of the disadvantages of traditional casts. Its design also allows for the integration of electronic therapies to decrease healing time.

BioSET

Series B in 2004
BioSET, Inc. is engaged in the medical research and development of synthetic bioactive peptides. It offers Amplex, an implantable combination device that is used in spine fusion surgery; products that are used for sports medicine applications; and peptide signaling molecules and various scaffold biomaterials for use in musculoskeletal applications. Its products are used in orthobiologics, spinal fusion, and other orthopedic applications. The company was founded in 2001 and is based in Rockville, Maryland. As of February 18, 2015, BioSET, Inc. operates as a subsidiary of Ferring Pharmaceuticals Inc.

Protein Discovery

Series C in 2008
Protein Discovery, Inc., a life sciences company, develops and commercializes sample preparation technologies that enable protein and peptide analysis using mass spectrometry. It provides Gelfree 8100, a fractionation system that partitions complex protein mixtures into liquid-phase molecular weight fractions; Passport 1200, a sample preparation system that enriches low molecular weight proteins and peptides, and removes matrix interferences for high-throughput quantification applications; and PPS Silent Surfactant, a protein preparation reagent that solubilizes membrane proteins and cleaves to eliminate detergent interference. The company also provides UPX universal protein extraction kit for detergent extraction of proteins from cells and tissues. It serves life science researchers and drug development scientists. The company markets its products through Agilent Technologies, as well as online in the United States and internationally. Protein Discovery, Inc. was founded as Qgenics Biosciences, Inc. in 2001 and changed its name to Protein Discovery, Inc. in April 2004. The company is based in Knoxville, Tennessee.

Spinal Restoration, Inc.

Series B in 2007
Spinal Restoration was formed to identify and develop new, early intervention, minimally invasive therapies for the treatment of chronic low back pain. The company’s first endeavor is the Biostat® System, a proprietary resorbable biologic compound and delivery system for the treatment of chronic disc pain. The new treatment specifically targets discogenic pain, which represents the single largest population of patients—an estimated four million adults—who suffer from chronic low back pain annually.

View Medical, Inc.

Seed Round in 2013
View Medical, Inc. provides a surgical lighting system for surgeons with a practical illumination device to focus on minute target areas. It also connects to overhead surgical light handles, and features a shaft that allows the user to direct the light onto the incision from any desired angle. The company was founded in 2013 and is based in Memphis, Tennessee.

Hapten Sciences

Seed Round in 2013
Hapten Sciences, Inc. operates as a biopharmaceutical company. It identifies and develops early-stage products, such as PDC-APB that acts as a vaccine to prevent contact dermatitis caused by exposure to urushiol oil in poison ivy, poison oak, or poison sumac plants. The company was incorporated in 2010 and is based in Memphis, Tennessee.

Idencia

Series A in 2015
First launch of Idencia was in Q1 2014

iScreen Vision

Series B in 2013
iScreen Vision, Inc. develops a screening equipment using a technology known as photoscreening to screen children’s vision for vision problems. The Company provides a fast, easy, and portable pediatric vision screening solution for infants and pre-school and school-age children. The company was formerly known as iScreen, LLC and changed its name in April 2009. iScreen Vision, Inc. was incorporated in 2009 and is based in Cordova, Tennessee.

EndoInSight

Seed Round in 2014
EndoInSight was founded to help reduce the terrible toll Colorectal Cancer (CRC) takes on society by providing clinicians with a cost-effective method for reducing the pain and discomfort associated with colonoscopy-based CRC screening. While inflating the colon is necessary to enhance visibility during colonoscopy, trapped air can leave patients feeling bloated and uncomfortable for hours following their procedure. It has long been known that using CO2 to inflate the colon can dramatically reduce post-procedural pain and discomfort yet adoption of the technique has been slow due to a lack of awareness concerning the benefits of CO2 and the capital expenditure related with current CO2 insufflation systems.

BioSET

Venture Round in 2007
BioSET, Inc. is engaged in the medical research and development of synthetic bioactive peptides. It offers Amplex, an implantable combination device that is used in spine fusion surgery; products that are used for sports medicine applications; and peptide signaling molecules and various scaffold biomaterials for use in musculoskeletal applications. Its products are used in orthobiologics, spinal fusion, and other orthopedic applications. The company was founded in 2001 and is based in Rockville, Maryland. As of February 18, 2015, BioSET, Inc. operates as a subsidiary of Ferring Pharmaceuticals Inc.

Hubble Telemedical

Seed Round in 2012
Hubble Telemedical is dedicated to enabling earlier detection of systemic and debilitating diseases that manifest in the retina - the light-sensitive membrane at the back of the eye that transmits visual information to the brain - for more effective treatment and patient care. In addition to eye diseases such as retinopathy, macular degeneration and glaucoma, a range of systemic diseases such cardiovascular and immune diseases can be detected in the retina. Early diagnosis is essential for effective treatment of these diseases. Unfortunately, many at-risk individuals do not receive annual retinal exams due to inconvenience or unavailability. The result is that many individuals go undiagnosed until severe damage has occurred, causing medical complications and increased healthcare costs. They are changing that paradigm. Thanks to their proprietary, award-winning Telemedical Retinal Image Analysis and Diagnosis (TRIAD™) technology, Hubble Telemedical enables screening and diagnosis where and when it is most convenient for the healthcare consumer. They partner with healthcare providers, insurance companies, and employers to bring the power of retinal screening to the consumer. Their services are fully HIPAA-compliant, secure, and easy to use –- and multi-site, peer-reviewed and published clinical studies have demonstrated their ability to dramatically increase annual screening compliance, thereby decreasing overall healthcare costs and, most importantly, improving patients' health. They invite you to contact us to learn more about their services and technology— and how they can work with you to bring the power of retinal image analysis to your organization.

Nanophthalmics

Seed Round in 2012
Nanophthalmics has developed and is licensing a patent-pending platform technology for microfabricated instruments that engage tissue in entirely new ways. Their focus is on employing novel surgical devices, techniques, and materials to improve current treatment outcomes for ophthalmic and other microsurgical diseases. Their first commercial device is a disposable, 510(k) exempt, corneal micro-punch that enhances healing of abrasions, recurrent erosions, and other corneal diseases by modifying tissue attachments at a cellular level.

Ortho Kinematics, Inc.

Series B in 2013
Ortho Kinematics is a spine diagnostics company, provides spine motion analysis and diagnostic services. The company provides information to spine clinicians to assist them in diagnosing and treating back and neck pain. Its solution includes KineGraph Vertebral Motion Analyzer, an automated functional diagnostic test for the spine that uses fluoroscopy to capture the spine in motion, producing patient-specific graphs of the kinematics for each vertebral level. The company was founded in 2006 and is based in Austin, Texas.

Tidal Wave Technology

Seed Round in 2013
Tidal Wave Technology manufactures a device to achieve a circumferential ablation of the nerves that surround the renal artery. It allows for renal denervation without placing any ablative elements within the renal artery. The company was founded in 2011 and is based in Memphis, Tennessee.

TriVirix International

Series D in 2002
TriVirix International is a U.S.-based company that manufactures and designs electro-mechanical, medical, diagnostic, analytical, and life-science devices. The company provides its clients with ribo printers, point-of-care blood testing analyzers, volumetric infusion pumps, and vital sign or conscious sedation monitors. TriVirix International is headquartered in Milaca, Minnesota.

ECOSURG

Seed Round in 2014
EcoSurg™ (pronounced eek-oh-surj) is a developer of environmentally-friendly surgical supplies that is dedicated to reducing the carbon footprint of the surgical suite. Their flagship product is the EcoSurg™ line of Patient Positioners. Disposable patient positioners are used in over 20 Million surgical procedures per year in the United States alone. These foam shapes are used to properly position patients in a variety of positions, ensuring safety, comfort, and adequate access to the surgical site. When disposed of, however, these products are harmful to the environment as they are made from materials that consist largely of petroleum-based derivatives. These compounds and the other hazardous byproducts from their production are not only harmful to the environment, but also incur higher handling and disposal costs that are inevitably passed on to the Customer.

Kereos, Inc.

Series B in 2005
Kereos, Inc., a biopharmaceutical company, develops a nanoscale drug delivery technology that enables targeted delivery of a range of therapeutic drug compounds, including existing drugs, new drug candidates, and compounds that are too toxic or too fragile to be delivered without the protection and targeting offered by its technology. It offers KER-1001, a cancer therapeutic that incorporates paclitaxel and a cancer therapeutic drug into the targeted nanodroplet; KER-1002, a cancer therapeutic that incorporates a natural product that has been shown to have anti-tumor efficacy in preclinical studies; and KER-1003 that incorporates a natural product that is effective as an anti-angiogenic. The company also provides KER 0001, a diagnostic application platform that detects the presence of angiogenesis. Kereos, Inc. was founded in 1999 and is based in Saint Louis, Missouri.

Urova Medical Inc.

Seed Round in 2012
Urova Medical was founded in Memphis, TN with the goal of providing a novel solution to cure stress urinary incontinence safely, effectively, and conveniently. Urova Medical’s technology was developed by an undergraduate team of talented biomedical engineers at Johns Hopkins University. The implant was designed extensively under the mentorship of physicians from the Johns Hopkins Hospital, the number one urological center in the US. Urova Medical has been part of the Zeroto510 Accelerator program sponsored by Innova Fund and MB Ventures, both venture capital firms based in Memphis

AxioMed LLC

Series B in 2005
AxioMed LLC designs and develops a disc replacement device that facilitates neck pain relief and restores normal spinal functions for patients with degenerative disc disease. AxioMed LLC was formerly known as AxioMed Spine Corporation and changed its name to AxioMed LLC in November 2014. The company was founded in 2001 and is based in Malden, Massachusetts.

Hubble Telemedical

Seed Round in 2013
Hubble Telemedical is dedicated to enabling earlier detection of systemic and debilitating diseases that manifest in the retina - the light-sensitive membrane at the back of the eye that transmits visual information to the brain - for more effective treatment and patient care. In addition to eye diseases such as retinopathy, macular degeneration and glaucoma, a range of systemic diseases such cardiovascular and immune diseases can be detected in the retina. Early diagnosis is essential for effective treatment of these diseases. Unfortunately, many at-risk individuals do not receive annual retinal exams due to inconvenience or unavailability. The result is that many individuals go undiagnosed until severe damage has occurred, causing medical complications and increased healthcare costs. They are changing that paradigm. Thanks to their proprietary, award-winning Telemedical Retinal Image Analysis and Diagnosis (TRIAD™) technology, Hubble Telemedical enables screening and diagnosis where and when it is most convenient for the healthcare consumer. They partner with healthcare providers, insurance companies, and employers to bring the power of retinal screening to the consumer. Their services are fully HIPAA-compliant, secure, and easy to use –- and multi-site, peer-reviewed and published clinical studies have demonstrated their ability to dramatically increase annual screening compliance, thereby decreasing overall healthcare costs and, most importantly, improving patients' health. They invite you to contact us to learn more about their services and technology— and how they can work with you to bring the power of retinal image analysis to your organization.

SweetBio, Inc.

Seed Round in 2018
SweetBio, Inc. researches, develops, and manufactures membranes that reduce complications and infections created by wounds, pressure ulcers, diabetic ulcers, surgical wounds, and abrasions. Its membrane incorporates medical grade Manuka honey for healing and fighting bacteria. SweetBio, Inc. was incorporated in 2015 and is headquartered in Memphis, Tennessee.

Cayenne Medical

Series C in 2008
Cayenne Medical, Inc. a sports medicine company, provides arthroscopic surgery products. It offers AperFix System that enables the surgeons to perform anterior cruciate ligament (ACL) reconstruction using the hamstring and various soft tissue grafts. The company also provides AperFix Femoral device to restore native knee kinematics; AperFix Tibial device for anatomic reconstruction applications; and iFix Interference Screw System for ACL reconstruction procedure using the bone-patellar tendon-bone and various bone-tendon-bone grafts. In addition, it offers interference screws and shoulder products. Cayenne Medical, Inc. was founded in 2005 and is based in Scottsdale, Arizona.

BioMimetic Therapeutics

Series C in 2004
BioMimetic Therapeutics is a biotechnology company that develops products to help stimulate the body natural tissue regenerative process. The company's products and product candidates include Augment Injectable and Augment Rotator Cuff for several orthopedic and sports medicine indications comprising the treatment of foot and ankle fusions, the stimulation of wrist fracture healing, and the surgical treatment of rotator cuff tears, as well as Augment Tendinopathy Injection for injuries cause of tendon overuse. BioMimetic Therapeutics was founded on 1999 and is headquartered in Franklin, Tennessee.

Hapten Sciences

Venture Round in 2014
Hapten Sciences, Inc. operates as a biopharmaceutical company. It identifies and develops early-stage products, such as PDC-APB that acts as a vaccine to prevent contact dermatitis caused by exposure to urushiol oil in poison ivy, poison oak, or poison sumac plants. The company was incorporated in 2010 and is based in Memphis, Tennessee.

Hubble Telemedical

Series A in 2014
Hubble Telemedical is dedicated to enabling earlier detection of systemic and debilitating diseases that manifest in the retina - the light-sensitive membrane at the back of the eye that transmits visual information to the brain - for more effective treatment and patient care. In addition to eye diseases such as retinopathy, macular degeneration and glaucoma, a range of systemic diseases such cardiovascular and immune diseases can be detected in the retina. Early diagnosis is essential for effective treatment of these diseases. Unfortunately, many at-risk individuals do not receive annual retinal exams due to inconvenience or unavailability. The result is that many individuals go undiagnosed until severe damage has occurred, causing medical complications and increased healthcare costs. They are changing that paradigm. Thanks to their proprietary, award-winning Telemedical Retinal Image Analysis and Diagnosis (TRIAD™) technology, Hubble Telemedical enables screening and diagnosis where and when it is most convenient for the healthcare consumer. They partner with healthcare providers, insurance companies, and employers to bring the power of retinal screening to the consumer. Their services are fully HIPAA-compliant, secure, and easy to use –- and multi-site, peer-reviewed and published clinical studies have demonstrated their ability to dramatically increase annual screening compliance, thereby decreasing overall healthcare costs and, most importantly, improving patients' health. They invite you to contact us to learn more about their services and technology— and how they can work with you to bring the power of retinal image analysis to your organization.

BioMimetic Therapeutics

Series C in 2005
BioMimetic Therapeutics is a biotechnology company that develops products to help stimulate the body natural tissue regenerative process. The company's products and product candidates include Augment Injectable and Augment Rotator Cuff for several orthopedic and sports medicine indications comprising the treatment of foot and ankle fusions, the stimulation of wrist fracture healing, and the surgical treatment of rotator cuff tears, as well as Augment Tendinopathy Injection for injuries cause of tendon overuse. BioMimetic Therapeutics was founded on 1999 and is headquartered in Franklin, Tennessee.

ECOSURG

Seed Round in 2012
EcoSurg™ (pronounced eek-oh-surj) is a developer of environmentally-friendly surgical supplies that is dedicated to reducing the carbon footprint of the surgical suite. Their flagship product is the EcoSurg™ line of Patient Positioners. Disposable patient positioners are used in over 20 Million surgical procedures per year in the United States alone. These foam shapes are used to properly position patients in a variety of positions, ensuring safety, comfort, and adequate access to the surgical site. When disposed of, however, these products are harmful to the environment as they are made from materials that consist largely of petroleum-based derivatives. These compounds and the other hazardous byproducts from their production are not only harmful to the environment, but also incur higher handling and disposal costs that are inevitably passed on to the Customer.
Applied Spine Technologies designs and develops specialty medical devices. The company offers spine stabilization systems that support patients with an injured or degenerated spine without eliminating motion. It is headquartered in Wellesley, Massachusetts.
Restore Medical Solutions is a medical device company focusing on products and techniques that promote SSI reduction, safety, and productivity within healthcare. The company manufactures a sterilization tray system that reduces the risk of infection from contaminated medical instruments. Its modular sterilization tray systems reduce the potential risk of infection from contaminated instruments and enable surgical departments to improve the quality of care while reducing cost. Founded in 2012, Restore Medical Solutions is headquartered in Memphis, Tennessee.

BioNanovations Corporation

Seed Round in 2012
Bell BioNanonostics Corp. focuses on monitoring of bacterial infection. Bell BioNanonostics Corp. is based in the United States.

Mobilizer

Seed Round in 2014
Mobilizer Inc., a graduate of the ZeroTo510 medical device startup accelerator, has created a six-wheeled holster for medical equipment in order to make medical ambulation easier and faster.

Health & Bliss

Seed Round in 2013
Health & Bliss Inc., a medical device company, designs, patents, and sells medical products and diagnostic tests. It develops Strep Test Anywhere, a point-of-care device that is designed to test patients anywhere for multiple infections, including strep throat, influenza A/B, chlamydia, gonorrhea, neisseria, hepatitis B/C, cholera, HIV, pertussis, malaria, syphilis, and other illnesses. The company is based in Memphis, Tennessee.

Ortho Kinematics, Inc.

Series A in 2011
Ortho Kinematics is a spine diagnostics company, provides spine motion analysis and diagnostic services. The company provides information to spine clinicians to assist them in diagnosing and treating back and neck pain. Its solution includes KineGraph Vertebral Motion Analyzer, an automated functional diagnostic test for the spine that uses fluoroscopy to capture the spine in motion, producing patient-specific graphs of the kinematics for each vertebral level. The company was founded in 2006 and is based in Austin, Texas.

Brainsgate

Venture Round in 2005
BrainsGate, Ltd., a medical device company, develops therapies for patients suffering from central nervous system (CNS) diseases. It offers a technology platform that involves electrical stimulation of the spheno-palatine ganglion (SPG), a nervous center known to increase cerebral blood flow. The company develops an ischemic stroke system that is based on an implantable electrode and is designed to deliver electrical stimulation to the spheno-palatine ganglion (SPG). Its system augments cerebral blood flow by using an external system temporarily attached to the patient’s cheek. BrainsGate, Ltd. was founded in 2000 and is based in Caesarea, Israel.

Brainsgate

Series C in 2008
BrainsGate, Ltd., a medical device company, develops therapies for patients suffering from central nervous system (CNS) diseases. It offers a technology platform that involves electrical stimulation of the spheno-palatine ganglion (SPG), a nervous center known to increase cerebral blood flow. The company develops an ischemic stroke system that is based on an implantable electrode and is designed to deliver electrical stimulation to the spheno-palatine ganglion (SPG). Its system augments cerebral blood flow by using an external system temporarily attached to the patient’s cheek. BrainsGate, Ltd. was founded in 2000 and is based in Caesarea, Israel.

AxioMed LLC

Series D in 2010
AxioMed LLC designs and develops a disc replacement device that facilitates neck pain relief and restores normal spinal functions for patients with degenerative disc disease. AxioMed LLC was formerly known as AxioMed Spine Corporation and changed its name to AxioMed LLC in November 2014. The company was founded in 2001 and is based in Malden, Massachusetts.

Compression Kinetics, Inc.

Seed Round in 2014
Compression Kinetics is developing the next generation of wearable technology, actively improving recovery time and athletic performance of its wearers. The pioneering dynamic compression technology fits into an $11b athletic compression apparel market. Compression Kinetics is transforming clinically proven compression therapy into a mobile, sleek and affordable wearable for the first time. With the active compression sleeve, any athlete can recover faster and improve their performance like the professionals.

Alveolus

Series B in 2004
Alveolus is a leader in the emerging field of non-vascular interventional stenting through next generation stent technology.

Anulex Technologies

Series E in 2010
Anulex Technologies focus on developing proprietary medical technology to repair and seal the soft tissue of the spine (anulus) for patients undergoing a surgical procedure to remove a herniated disc (discectomy).