Psilos II

Psilos Group Managers, LLC is a venture capital firm founded in 1998 and headquartered in New York, with additional offices in California, New Mexico, and Massachusetts. The firm specializes in investments in mid to later stage healthcare companies, focusing on healthcare services, healthcare information technology, and medical technology, including devices and diagnostics. Psilos typically invests between $8 million and $15 million per deal, with a total investment expectation of $20 million to $25 million over the life of an investment. The firm aims to take lead or co-lead positions in financing rounds, primarily targeting the second or third rounds of institutional investment. Psilos actively seeks to partner with experienced management teams and aims to support companies that have the potential to transform the healthcare sector through innovative services and technologies. By leveraging its extensive network of industry relationships, Psilos strives to enhance the strategic development of its portfolio companies, fostering their growth and facilitating successful liquidity events.

David (Dave) Eichler

Managing Member

Stephen M. Krupa

Managing Partner & Chief Executive Officer

Matt Levin

Managing Partner

Joseph R. Riley

Chief Administrative Office and Managing Partner

Albert S. Waxman

Founder and Managing Partner

32 past transactions

Gamma Medica

Series B in 2014
Gamma Medica, Inc. is proud to offer the LumaGEM® MBI System. As the first commercially available, FDA cleared, planar, dual head, fully solid state digital imaging system utilizing cadmium zinc telluride (CZT) technology used for breast imaging, LumaGEM is able to detect millimeter-size breast cancers missed by mammography, especially in women with dense breast tissue.

Gamma Medica

Series A in 2013
Gamma Medica, Inc. is proud to offer the LumaGEM® MBI System. As the first commercially available, FDA cleared, planar, dual head, fully solid state digital imaging system utilizing cadmium zinc telluride (CZT) technology used for breast imaging, LumaGEM is able to detect millimeter-size breast cancers missed by mammography, especially in women with dense breast tissue.

SeeChange Health

Series C in 2013
We provide the information, tools, and technology to help employees take control of their health, while companies take control of their health expenses. Whether you’re looking for flexible, self-administered health plans or customizable engagement software, our SeeChange Health Solutions make it easy to administer value-based benefits within your company.

SeeChange Health

Series B in 2011
We provide the information, tools, and technology to help employees take control of their health, while companies take control of their health expenses. Whether you’re looking for flexible, self-administered health plans or customizable engagement software, our SeeChange Health Solutions make it easy to administer value-based benefits within your company.

Gamma Medica-Ideas

Series A in 2009
Gamma Medica-Ideas (GM-I) develops novel technologies to markets that improve patient health through early diagnosis of disease, improved patient treatment and by enabling new drug discovery. GM-I also develops medical devices and techniques to support molecular imaging of living subjects, targeted at the pharmaceutical pre-clinical research and clinical diagnostic markets. GM-I is dedicated to developing cutting-edge, fully digital imaging systems using the most advanced solid-state technologies.

SeeChange Health

Series A in 2009
We provide the information, tools, and technology to help employees take control of their health, while companies take control of their health expenses. Whether you’re looking for flexible, self-administered health plans or customizable engagement software, our SeeChange Health Solutions make it easy to administer value-based benefits within your company.

VeraLight

Series C in 2008
VeraLight is a medical device company that was established in October 2004 to focus on a comprehensive approach to non-invasive type 2 diabetes and pre-diabetes screening with the proprietary SCOUT DS® system. Their mission is to help stem the tide of the worldwide diabetes epidemic by driving early diabetes detection, thus enabling initiation of therapies that can prevent diabetes or reduce its complications. The company develops and acquires intellectual property, products, and services that contribute to this mission.

OmniGuide

Series E in 2008
OmniGuide is a medical device company focused on developing and commercializing minimally invasive surgical tools that utilize CO2 laser technology. Their flagship product, the OmniGuide Beampath CO2 laser energy system, offers a compact solution for precise cutting, ablation, and coagulation, while minimizing thermal damage to surrounding healthy tissue. This versatile system is designed to enhance surgical outcomes by providing high-quality optical scalpels that improve clinical value and expand the possibilities of minimally invasive procedures. The company is dedicated to advancing patient care by delivering indication-specific surgical instruments and exceptional customer service, ultimately aiming to improve patients' quality of life. OmniGuide's products are cleared for sale in the United States and carry CE marking, reflecting their compliance with safety and efficacy standards.

HealthEdge

Venture Round in 2008
HealthEdge provides modern, disruptive technology that delivers for the first time, a suite of products that enables healthcare payors to leverage new business models, improve outcomes, drastically reduce administrative costs, and connect everyone in the healthcare delivery cycle. Their next-generation enterprise product suite, HealthRules, is built on modern, patented technology and is delivered to customers via the HealthEdge Cloud or on-site deployment. They enable their customers to radically innovate, drastically reduce costs, and efficiently address the business imperatives of the evolving healthcare economy. HealthEdge was founded by Albert Waxman of Psilos Group and Rob Gillette in December 2004. In January 2005, the company acquired over $125 million in intellectual property and other assets. This technology served as the foundation for the patented, award-winning HealthRules product suite. In December 2012, HealthEdge acquired Click4Care, a care management, and utilization management software company, adding next-generation clinical capabilities to the award-winning HealthRules product suite. HealthEdge is headquartered in Burlington, Massachusetts, and maintains an R&D center in Powell, Ohio.

Mauna Kea Technologies

Series B in 2008
Mauna Kea Technologies is a global medical device company headquartered in Paris, France, that specializes in the development and marketing of technologies aimed at improving the diagnosis and treatment of cancers and other diseases. Founded in 2000, the company’s flagship product, Cellvizio, is a confocal laser endomicroscopy platform that enables real-time in vivo microscopic visualization of tissues at the cellular level. This innovative technology provides physicians and researchers with critical imaging capabilities, enhancing diagnostic accuracy and treatment effectiveness. Cellvizio has received regulatory clearance and approval for various applications in the United States and over 40 countries worldwide, underscoring its significance in the medical field.

AngioScore

Series E in 2007
AngioScore Inc. develops, manufactures and markets the AngioSculpt Scoring Balloon Catheter for both the coronary and peripheral interventional markets. Designed specifically to address the limitations of conventional angioplasty balloon catheters, AngioSculpt combines a semi-compliant balloon with an innovative nitinol scoring element.

Extend Health

Series B in 2007
Extend Health provides defined contribution benefit and insurance programs to the employees and retirees of corporate America, with a particular focus on helping clients choose Medicare programs.

Click4Care

Series A in 2007
Click4Care, Inc. provides medical management software for payers, providers, and patients. It offers ThinkHealth, which automates utilization case, disease, and population health management workflows. The company was founded in 1999 and is headquartered in Powell, Ohio.

Health Hero Network

Series B in 2006
Health Hero Network, Inc. develops and markets technology solutions for remote health monitoring and management. The company provides health management programs delivering personalized daily monitoring and patient education, and information to care providers. It also offers Health Buddy system that serves as the interface between patients at home and care providers, facilitating patient education and monitoring of chronic conditions. The company's Health Buddy system includes monitoring technologies, clinical information databases, Internet-enabled decision support tools, health management programs, and content development software tools. It serves hospitals, health plans, government health organizations, disease management companies, and pharmaceutical companies or universities conducting clinical trials or studies. The company was founded in 1988 and is based in Palo Alto, California. As of December 19, 2007, Health Hero Network, Inc. operates as a subsidiary of Robert Bosch GMBH.

VeraLight

Series B in 2006
VeraLight is a medical device company that was established in October 2004 to focus on a comprehensive approach to non-invasive type 2 diabetes and pre-diabetes screening with the proprietary SCOUT DS® system. Their mission is to help stem the tide of the worldwide diabetes epidemic by driving early diabetes detection, thus enabling initiation of therapies that can prevent diabetes or reduce its complications. The company develops and acquires intellectual property, products, and services that contribute to this mission.

AngioScore

Series D in 2006
AngioScore Inc. develops, manufactures and markets the AngioSculpt Scoring Balloon Catheter for both the coronary and peripheral interventional markets. Designed specifically to address the limitations of conventional angioplasty balloon catheters, AngioSculpt combines a semi-compliant balloon with an innovative nitinol scoring element.

Acuity Pharmaceuticals

Series B in 2004
Acuity Pharmaceuticals is a pharmaceutical company that is focused on the treatment and prevention of ophthalmic diseases. It develops treatments for age-related macular degeneration and diabetic retinopathy. The company offers Cand5, a clinical compound that is able to shut down vascular endothelial growth factor. Acuity Pharmaceuticals was acquired by OPKO Health in June 2011. Acuity Pharmaceuticals was founded in 2007 and is based in Philadelphia, Pennsylvania.

AngioScore

Series B in 2004
AngioScore Inc. develops, manufactures and markets the AngioSculpt Scoring Balloon Catheter for both the coronary and peripheral interventional markets. Designed specifically to address the limitations of conventional angioplasty balloon catheters, AngioSculpt combines a semi-compliant balloon with an innovative nitinol scoring element.

InSound Medical

Series D in 2004
InSound Medical, Inc., a privately held, venture-backed company based in Newark, California, develops and manufactures next-generation hearing solutions. Major investors include Johnson & Johnson, DeNovo Ventures, CMEA Ventures, and Psilos Group Managers, LLC.

deNovis

Series C in 2004
deNovis Inc. is a leading provider of advanced transaction processing and information management solutions for the health insurance and health care benefits administration industry. deNovis's highly innovative claims processing and data management software enables commercial and government health plans to reduce administrative costs, expand their range of products and services, increase speed-to-market of new products and enhance the quality of customer service. The company's flagship software product—eHD™—serves as the core administrative platform for health plans and is designed to deliver the sophistication necessary to meet both existing and emerging needs of commercial, Medicare and Medicaid healthcare benefits administrators. deNovis is also known for its technical innovations, including HICL™ technology, which allows complex healthcare transaction systems to be programmed by business analysts rather than computer programmers, using English language commands and the actual policies and business rules of the health plan. deNovis's customer roster includes large commercial insurers and the U. S. Department of Health and Human Services—the nation's largest purchaser of healthcare and a provider of healthcare benefits to almost 80 million Americans. The company's strategic alliance partners include IBM Corporation and Deloitte Consulting. deNovis enterprise solutions for health plans are available for installation at customer locations or can be delivered on an outsourced or remote-hosted basis. The company is privately held and is headquartered in Lexington, Massachusetts.

Cohesive Technologies

Series B in 2003
Cohesive Technologies Inc. designs, manufactures, and markets breakthrough liquid chromatography (LC) solutions for the drug discovery, pharmaceutical, contract research, and clinical diagnostic industries. The company has developed patented technologies and a wide range of chromatographic products designed to significantly improve productivity by accelerating the separation, purification, and analysis of molecules in bioanalysis. With a strong depth of knowledge in column chemistry, applications, engineering, software development, and quality management, Cohesive Technologies leads the industry in the research, development, and production of LC technologies that accelerate the pace of customers' drug discovery and development efforts.

Estech

Series B in 2003
ESTECH is a privately held medical device manufacturing and distribution company located in San Ramon, California. The company was founded by Arthur and Raymond Bertolero in 1996 with an emphasis on least invasive products for cardiac surgery. ESTECH has worldwide distribution and has consistently attracted goal oriented professionals who represent the brightest minds in the medical device industry. The in-depth professional experience and tireless dedication of the ESTECH Team has allowed the company to achieve rapid and sustained success in this highly competitive environment. ESTECH is proud of each employee from every department and thanks them for their contribution and support.

OneShield, Inc.

Series C in 2002
OneShield, Inc. develops business software solutions tailored for the global property, casualty, and general insurance industries. The company offers a range of enterprise-class products, including policy management, billing, claims processing, and rating solutions, as well as tools for managing general agencies and third-party administrators. OneShield's software can be deployed in the cloud or on-premise, featuring a tool-based open architecture that enhances operational efficiency. The company's offerings also encompass business intelligence and analytics solutions aimed at simplifying core system complexities while providing seamless upgrades and lower total costs of ownership. Established in 1999 and headquartered in Marlborough, Massachusetts, OneShield maintains additional offices in Australia, Canada, and India, and has formed strategic partnerships with several technology firms to enhance its service offerings.

deNovis

Series B in 2001
deNovis Inc. is a leading provider of advanced transaction processing and information management solutions for the health insurance and health care benefits administration industry. deNovis's highly innovative claims processing and data management software enables commercial and government health plans to reduce administrative costs, expand their range of products and services, increase speed-to-market of new products and enhance the quality of customer service. The company's flagship software product—eHD™—serves as the core administrative platform for health plans and is designed to deliver the sophistication necessary to meet both existing and emerging needs of commercial, Medicare and Medicaid healthcare benefits administrators. deNovis is also known for its technical innovations, including HICL™ technology, which allows complex healthcare transaction systems to be programmed by business analysts rather than computer programmers, using English language commands and the actual policies and business rules of the health plan. deNovis's customer roster includes large commercial insurers and the U. S. Department of Health and Human Services—the nation's largest purchaser of healthcare and a provider of healthcare benefits to almost 80 million Americans. The company's strategic alliance partners include IBM Corporation and Deloitte Consulting. deNovis enterprise solutions for health plans are available for installation at customer locations or can be delivered on an outsourced or remote-hosted basis. The company is privately held and is headquartered in Lexington, Massachusetts.

MRxonline

Venture Round in 2001
They are an Internet Application Service Provider (ASP) offering a suite of web-based medical billing and compliance management services. MRxonline.com has developed key business-to-business alliances that allow us to deliver the first scalable, dedicated Internet medical billing application to third-party billing companies, large practices, PHO's, IPA's, payers and practice management organizations. This new approach to practice management provides cost-effective solutions such as coding compliance monitoring and reporting at a level that is generally unavailable to physician practices. By existing entirely as an Internet application, hardware and software capital investments as well as system maintenance costs are dramatically reduced thereby allowing the physician to focus on practicing medicine, not practice management.

eMotion

Venture Round in 2000
eMotion, Inc. provides hosted business applications for managing digital media assets and marketing content. It offers hosted digital asset management software, which enables corporations, advertising agencies, and nonprofit organizations to develop, manage, and distribute media, such as digital photos, adobe or quark files, video, and audio. This product also enables users to distribute marketing materials across dispersed offices, sales teams, and vendors. The company offers its product for business applications, such as brand portals, marketing extranets, and digital asset libraries. It serves blue-chip companies, entertainment and broadcast companies, advertising agencies, and government agencies. EMotion, Inc. was formed from the merger of Cinebase Software and Picture Networks International in 2000 and is headquartered in San Francisco, California. eMotion, Inc. formerly operated as a subsidiary of Corbis Corporation. The company also has an additional office in Vienna, Virginia. As of July 10, 2008, eMotion, Inc. operates as a subsidiary of Artesia Technologies, Inc.

Active Health Managment

Series A in 2000
ActiveHealth Management is a national leader in population health management and passionate about helping every person achieve his or her best health. They deliver personalized guidance through their analytics and insights, care management, health, lifestyle and wellness programs to help their customers improve quality of care, lower healthcare costs, and drive sustained member engagement and behavior change. ActiveHealth® collaborates with employers, health plans, governments and providers currently helping more than 20 million people live their healthiest lives. ActiveHealth Management is an independent subsidiary of Aetna (NYSE: AET)

Definity Health

Venture Round in 2000
Definity Health is a company based in Saint Louis Park, Minnesota, established in 1998. It specializes in developing consumer-driven healthcare plans and activation strategies aimed at improving the healthcare experience for patients. The company creates programs and products that educate individuals, empowering them to make informed decisions regarding their treatment options. Definity Health was acquired by UnitedHealth Group, further integrating its focus on enhancing consumer engagement in healthcare.

Health Hero Network

Venture Round in 2000
Health Hero Network, Inc. develops and markets the industry's most advanced tools and technologies for delivering structured.

HealthAnswers Education

Series A in 2000
HealthAnswers Education is a developer of sales training and medical education programs for the pharmaceutical/biotech industry. HealthAnswers is a leading full-service sales training agency specializing in blended learning solutions for today's pharmaceutical and biotech sales professionals and managers. During the past 25 years we have trained tens of thousands of sales professionals across a wide range of disease categories via every live and virtual training platform available in the industry. As problem solvers, HealthAnswers partners with pharmaceutical and biotechnology leaders to determine the most effective educational and training programs that exceed expectations. We have proven expertise delivering clinical and product training, skill and performance development training, as well as Sales Force Effectiveness (SFE) activities such as needs assessments, curriculum audits, and competency model development. At HealthAnswers, we pride ourselves on our creative design while ensuring educational and learning objectives are met.

ClickThings

Venture Round in 2000
ClickThings

Health Hero Network

Venture Round in 1998
Health Hero Network, Inc. develops and markets technology solutions for remote health monitoring and management. The company provides health management programs delivering personalized daily monitoring and patient education, and information to care providers. It also offers Health Buddy system that serves as the interface between patients at home and care providers, facilitating patient education and monitoring of chronic conditions. The company's Health Buddy system includes monitoring technologies, clinical information databases, Internet-enabled decision support tools, health management programs, and content development software tools. It serves hospitals, health plans, government health organizations, disease management companies, and pharmaceutical companies or universities conducting clinical trials or studies. The company was founded in 1988 and is based in Palo Alto, California. As of December 19, 2007, Health Hero Network, Inc. operates as a subsidiary of Robert Bosch GMBH.