New Science Ventures

New Science Ventures is a venture capital firm established in 2004 and based in Greenwich, Connecticut. The firm specializes in early and late-stage investments primarily in the life sciences and information technology sectors. It targets companies that employ innovative scientific approaches to tackle significant unmet needs, aiming to achieve substantial improvements in performance. The firm's investment focus includes pharmaceuticals, biologics, medical devices, diagnostics, and various IT-related fields such as data analytics and artificial intelligence. New Science Ventures operates across the United States, Western Europe, and the Asia-Pacific region. The team's expertise encompasses strategy, corporate planning, operations, and leadership development, enabling them to support the growth of their portfolio companies effectively.

Andrew Abrams

Partner

Jean-Pierre Bizet Ph.D

Partner & Senior Advisor

John L. Cecil

Partner and Senior Advisor

Tom Lavin

Co-Founder & Partner

Brenda Marex

Partner and Chief Financial Officer

Raju Mohan Ph.D

Partner & Senior Advisor

Vivek Mohindra

Partner

Somu Subramaniam

Managing Partner

73 past transactions

Paragraf

Series B in 2022
Paragraf Ltd. is a graphene technology development company based in Somersham, United Kingdom, established in 2015. The company specializes in the production of two-dimensional materials, particularly graphene, and focuses on developing graphene-based electronic devices, green energy generation devices such as solar photovoltaic cells, and various sensors. By leveraging innovative methods, Paragraf aims to unlock the full potential of graphene and advance its applications across multiple technology sectors. The company's commitment to driving the adoption of this versatile material positions it as a key player in the field of advanced materials and their transformative capabilities.

NorthSea Therapeutics

Series C in 2021
NorthSea Therapeutics B.V. is a biotechnology company based in Naarden, the Netherlands, established in 2017. The company specializes in the development and manufacturing of novel therapeutics aimed at addressing metabolic, inflammatory, and fibrotic diseases. It focuses on creating first-in-class, oral lipid therapeutics through its proprietary Structurally Engineered Fatty Acid (SEFA) technology. One of its key products, icosabutate, is a structurally engineered fatty acid designed to treat inflammatory and liver diseases. The SEFA technology enables the development of candidates that exhibit a range of biological effects, effectively targeting issues such as dyslipidemia, insulin resistance, hepatic inflammation, and fibrosis across various models.

Cambridge Epigenetix

Series D in 2021
Cambridge Epigenetix Limited, a bioscience company, provides epigenetic tools. It offers TrueMethyl oxidative bisulfite sequencing (oxBS-Seq), a technology that enables single-base resolution sequencing of hydroxymethyl cytosine (5hmC) and methylcytosine (5mC), as well as provides the analysis of the DNA methylome. The company’s products include TrueMethyl 6 and TrueMethyl 24 kits that enable quantitative measurement of 5hmC and 5mC, single-base resolution of methylation and hydroxymethylation analysis, and confirmation of the location of unmethylated cytosines. It offers its products through third party vendors, as well as online to business customers in the United Kingdom and internationally. Cambridge Epigenetix Limited was founded in 2012 and is based in Babraham, United Kingdom.

Novadip Biosciences

Series B in 2021
Novadip Biosciences SA is a biopharmaceutical company that develops process and distribution platform for tissue regeneration. It focuses on autologous cell therapies for critical size tissue reconstruction; allogeneic therapeutics for smaller and prevalent tissue defects; and miRNA/exosome-based therapeutics for systemic tissue and other diseases. The company was founded in 2013 and is based in Mont-Saint-Guibert, Belgium.

BrightVolt

Series B in 2021
BrightVolt, Inc. is engaged in the design, development, and scale manufacturing of ultra thin film batteries to power various Internet connected devices, such as medical patches, sensor labels, and power cards. It also develops custom solid state thin film batteries and power solutions for client’s IoT devices; Flexion solid state thin film lithium polymer batteries; and thin micro electronics. The company’s products are sold in the United States and internationally. BrightVolt, Inc. was formerly known as Solicore, Inc. The company was incorporated in 1998 and is based in Redmond, Washington.

Phase Four

Series B in 2021
Phase Four LLC manufactures satellite propulsion systems. It also provides CubeSats ambipolar thruster, an electrodeless permanent magnet helicon thruster; and Maxwell, a turn key plasma propulsion solution for small satellites. The company’s products are used in commercial, civil, and scientific space missions. The company was incorporated in 2015 and is based in Pasadena, California.

Zeotap

Series C in 2020
Zeotap GmbH is a customer intelligence platform that assists brands in understanding their customers and predicting their behaviors, which enables more effective investments in customer relationships and products. Established in 2014 and headquartered in Berlin, Germany, Zeotap combines identity and profile data from exclusive enterprise partners with a comprehensive technology platform for unifying first-party customer data, identity resolution, third-party data enrichment, and analytics. The company emphasizes data privacy and security, adhering to strict governance and compliance measures, and holds certifications such as ISO 27001 and CSA STAR. Zeotap serves over 70 of the top 100 global brands, including Unilever, BBVA, and Mercedes-Benz, and has expanded its operations to locations such as New York, Bengaluru, Madrid, and Milan. With a workforce of 145 employees, Zeotap has raised more than $45 million from international investors.

NorthSea Therapeutics

Series B in 2020
NorthSea Therapeutics B.V. is a biotechnology company based in Naarden, the Netherlands, established in 2017. The company specializes in the development and manufacturing of novel therapeutics aimed at addressing metabolic, inflammatory, and fibrotic diseases. It focuses on creating first-in-class, oral lipid therapeutics through its proprietary Structurally Engineered Fatty Acid (SEFA) technology. One of its key products, icosabutate, is a structurally engineered fatty acid designed to treat inflammatory and liver diseases. The SEFA technology enables the development of candidates that exhibit a range of biological effects, effectively targeting issues such as dyslipidemia, insulin resistance, hepatic inflammation, and fibrosis across various models.

DUST Identity

Series A in 2019
DUST Identity, Inc. develops an authentication system technology that utilizes nano-diamonds to create an unclonable identity layer on any object for any supply chain. It also provides an optical scanner and cloud-based infrastructure that provides an interface to the object identity. DUST Identity, Inc. was formerly known as Diamond Nanotechnalogies, Inc. The company was founded in 2011 and is based in Framingham, Massachusetts with an additional office in Princeton, New Jersey.

PlanetIQ

Series B in 2019
PlanetiQ LLC, established in 2012 and headquartered in Bethesda, Maryland, is dedicated to launching satellites that enhance weather forecasting, climate monitoring, and space weather prediction. As the demand for global atmospheric data increases due to rising natural disaster costs and the impacts of climate change, traditional government-funded satellite programs struggle to meet these needs. Aging spacecraft and budget constraints contribute to significant data gaps that hinder accurate monitoring and forecasting of daily weather events, hurricanes, floods, droughts, and long-term climate trends. By addressing these challenges, PlanetiQ aims to provide timely and precise atmospheric data to improve weather and climate models, ultimately benefiting public safety and environmental management.

Paradigm Diagnostics

Series B in 2019
Paradigm Diagnostics specializes in advanced cancer diagnostics and biomarker-driven clinical trials, aiming to enhance treatment options for cancer patients. Utilizing next-generation sequencing and comprehensive biomarker analysis, Paradigm assesses the genomic and proteomic characteristics of individual tumors. This information allows for a detailed understanding of the specific cancer pathways involved and the potential therapies tailored to each patient's unique tumor profile. By focusing on personalized medicine, Paradigm empowers healthcare providers to offer targeted treatment strategies, ultimately improving patient outcomes in cancer care.

BrightVolt

Convertible Note in 2019
BrightVolt, Inc. is engaged in the design, development, and scale manufacturing of ultra thin film batteries to power various Internet connected devices, such as medical patches, sensor labels, and power cards. It also develops custom solid state thin film batteries and power solutions for client’s IoT devices; Flexion solid state thin film lithium polymer batteries; and thin micro electronics. The company’s products are sold in the United States and internationally. BrightVolt, Inc. was formerly known as Solicore, Inc. The company was incorporated in 1998 and is based in Redmond, Washington.

DUST Identity

Seed Round in 2018
DUST Identity, Inc. develops an authentication system technology that utilizes nano-diamonds to create an unclonable identity layer on any object for any supply chain. It also provides an optical scanner and cloud-based infrastructure that provides an interface to the object identity. DUST Identity, Inc. was formerly known as Diamond Nanotechnalogies, Inc. The company was founded in 2011 and is based in Framingham, Massachusetts with an additional office in Princeton, New Jersey.

Svelte Medical Systems

Venture Round in 2018
Svelte Medical Systems, Inc. is a privately held company that specializes in the design and development of innovative balloon-expandable stents for patients undergoing percutaneous coronary interventions to treat atherosclerosis. Founded in 2007, the company is based in New Providence, New Jersey, and aims to address critical clinical issues in the coronary stent market, which is valued at approximately $5 billion. Svelte offers two primary products: the SLENDER Integrated Delivery System, a drug-eluting coronary stent-on-a-wire designed to facilitate transradial interventions, and the DIRECT Rapid Exchange System, which enhances direct stenting and high-pressure post-dilatations. Both systems utilize proprietary technologies to improve stent deliverability, reduce the need for additional guide wires and balloons, and ultimately enhance patient outcomes while minimizing procedure costs and risks.

Isorg

Series B in 2018
Isorg SA, founded in 2010 and based in Grenoble, France, specializes in the development and manufacturing of organic and printed electronic devices, particularly in the fields of photonics and image sensors. The company is noted for its innovative high-performance opto-electronic sensors, which can be integrated into various products, transforming surfaces made of plastic or glass into smart interfaces. Isorg offers a comprehensive range of services, from proof-of-concept to mass production, catering to diverse applications across consumer electronics, home appliances, smart buildings, industrial sectors, healthcare, and safety. Additionally, the company provides support for product development and integration. Its technology includes large-area image sensors and photodetectors, contributing to sectors such as medical imaging, non-destructive testing, and data security.

Cambridge Epigenetix

Series C in 2018
Cambridge Epigenetix Limited, a bioscience company, provides epigenetic tools. It offers TrueMethyl oxidative bisulfite sequencing (oxBS-Seq), a technology that enables single-base resolution sequencing of hydroxymethyl cytosine (5hmC) and methylcytosine (5mC), as well as provides the analysis of the DNA methylome. The company’s products include TrueMethyl 6 and TrueMethyl 24 kits that enable quantitative measurement of 5hmC and 5mC, single-base resolution of methylation and hydroxymethylation analysis, and confirmation of the location of unmethylated cytosines. It offers its products through third party vendors, as well as online to business customers in the United Kingdom and internationally. Cambridge Epigenetix Limited was founded in 2012 and is based in Babraham, United Kingdom.

Paradigm Diagnostics

Series B in 2018
Paradigm Diagnostics specializes in advanced cancer diagnostics and biomarker-driven clinical trials, aiming to enhance treatment options for cancer patients. Utilizing next-generation sequencing and comprehensive biomarker analysis, Paradigm assesses the genomic and proteomic characteristics of individual tumors. This information allows for a detailed understanding of the specific cancer pathways involved and the potential therapies tailored to each patient's unique tumor profile. By focusing on personalized medicine, Paradigm empowers healthcare providers to offer targeted treatment strategies, ultimately improving patient outcomes in cancer care.

Morrow Optics

Series A in 2018
Our view is a world where nothing is missed and one pair does it all. Because there’s more to see than ever before, and you deserve to see the bigger picture without edges or limitations. Our story starts with Jelle De Smet and Paul Marchal, two pioneers who with combined experience in electronics and nanotechnology invented the Autofocal lens. They saw a better way, where ageing eyesight is no longer a burden and progressive lenses were a prequel. And so Morrow was founded in 2016 — followed by years of research, development and meticulous fine-tuning. We now launch our flagship Autofocal Eyewear that combines Active Liquid Crystal and a two-layer corrective lens to transform your vision — both near and far — at the touch of a button. In our eyes, independence is a state of mind. It’s the unshackled freedom to do what you want and on your own terms, whilst always improving. Discover why there is always mor’ to see.

ChromaCure

Venture Round in 2018
ChromaCure will launch a drug development program to identify potential new candidates that selectively and potently inhibit cancer targets and potentially provide novel therapy for multiple forms of cancer, either as monotherapy or in combination with immunotherapy or chemotherapy.

Escalier Biosciences

Series B in 2018
Escalier Biosciences BV is a privately held biopharmaceutical company developing novel small molecule therapeutics that target ROR?t for the treatment of psoriasis and other autoimmune disorders. Escalier's lead topical and oral drug candidates are currently in late stage preclinical studies. Escalier is registered in The Netherlands with offices in Nijmegen, The Netherlands and Encinitas, California.

NorthSea Therapeutics

Series A in 2017
NorthSea Therapeutics B.V. is a biotechnology company based in Naarden, the Netherlands, established in 2017. The company specializes in the development and manufacturing of novel therapeutics aimed at addressing metabolic, inflammatory, and fibrotic diseases. It focuses on creating first-in-class, oral lipid therapeutics through its proprietary Structurally Engineered Fatty Acid (SEFA) technology. One of its key products, icosabutate, is a structurally engineered fatty acid designed to treat inflammatory and liver diseases. The SEFA technology enables the development of candidates that exhibit a range of biological effects, effectively targeting issues such as dyslipidemia, insulin resistance, hepatic inflammation, and fibrosis across various models.

Zeotap

Series B in 2017
Zeotap GmbH is a customer intelligence platform that assists brands in understanding their customers and predicting their behaviors, which enables more effective investments in customer relationships and products. Established in 2014 and headquartered in Berlin, Germany, Zeotap combines identity and profile data from exclusive enterprise partners with a comprehensive technology platform for unifying first-party customer data, identity resolution, third-party data enrichment, and analytics. The company emphasizes data privacy and security, adhering to strict governance and compliance measures, and holds certifications such as ISO 27001 and CSA STAR. Zeotap serves over 70 of the top 100 global brands, including Unilever, BBVA, and Mercedes-Benz, and has expanded its operations to locations such as New York, Bengaluru, Madrid, and Milan. With a workforce of 145 employees, Zeotap has raised more than $45 million from international investors.

Caringo

Series B in 2016
Caringo Inc. is an innovative software provider focused on delivering the most advanced object-based technology for accessing, storing and distributing unstructured or file-based data. Its flagship product, CAStor, enables private cloud storage that dramatically improves the scope and economics of storing content by enabling customers to implement robust storage clusters without being locked into proprietary hardware. Founded on the operating principle that things should be made as simple as possible and a customer-first focus, Caringo makes content and file storage affordable, scalable, fast and easy.

BrightVolt

Series B in 2016
BrightVolt, Inc. is engaged in the design, development, and scale manufacturing of ultra thin film batteries to power various Internet connected devices, such as medical patches, sensor labels, and power cards. It also develops custom solid state thin film batteries and power solutions for client’s IoT devices; Flexion solid state thin film lithium polymer batteries; and thin micro electronics. The company’s products are sold in the United States and internationally. BrightVolt, Inc. was formerly known as Solicore, Inc. The company was incorporated in 1998 and is based in Redmond, Washington.

Vuv Analytics

Series B in 2016
VUV Analytics, Inc. specializes in the manufacture and marketing of vacuum ultraviolet (VUV) detectors, which enhance chemical analysis accuracy through advanced spectroscopy techniques. Established in 2009 as a spin-off from a semiconductor equipment company, VUV Analytics leverages the expertise of its founders, who possess extensive knowledge in hardware, software, analysis, and intellectual property related to VUV technologies. The company offers products such as the VGA-100, a VUV absorption spectroscopy instrument, and gas chromatography detectors, which are utilized for both identification and quantification of various compounds. Its technology finds applications across multiple industries, including petroleum and natural gas, environmental science, petrochemicals, agrochemicals, and food and beverage safety. VUV Analytics is headquartered in Cedar Park, Texas, and has developed a substantial intellectual property portfolio, including numerous issued and pending patents.

Kateeva

Series E in 2016
Kateeva is focused on advancing OLED production technology through its innovative inkjet printing manufacturing equipment. This approach enables the production of flexible and large-size OLEDs at high volumes, resulting in longer lifetimes, higher yields, and reduced production costs. Kateeva's technology represents a significant breakthrough, as it is the first economically viable method for the mass production of OLEDs using printing techniques. This innovation is poised to transform the display industry, making large OLED televisions and lightweight wearable devices more accessible to consumers. By enhancing the efficiency and cost-effectiveness of OLED manufacturing, Kateeva aims to drive the next wave of advancements in consumer electronics.

Cambridge Epigenetix

Series B in 2016
Cambridge Epigenetix Limited, a bioscience company, provides epigenetic tools. It offers TrueMethyl oxidative bisulfite sequencing (oxBS-Seq), a technology that enables single-base resolution sequencing of hydroxymethyl cytosine (5hmC) and methylcytosine (5mC), as well as provides the analysis of the DNA methylome. The company’s products include TrueMethyl 6 and TrueMethyl 24 kits that enable quantitative measurement of 5hmC and 5mC, single-base resolution of methylation and hydroxymethylation analysis, and confirmation of the location of unmethylated cytosines. It offers its products through third party vendors, as well as online to business customers in the United Kingdom and internationally. Cambridge Epigenetix Limited was founded in 2012 and is based in Babraham, United Kingdom.

Svelte Medical Systems

Private Equity Round in 2016
Svelte Medical Systems, Inc. is a privately held company that specializes in the design and development of innovative balloon-expandable stents for patients undergoing percutaneous coronary interventions to treat atherosclerosis. Founded in 2007, the company is based in New Providence, New Jersey, and aims to address critical clinical issues in the coronary stent market, which is valued at approximately $5 billion. Svelte offers two primary products: the SLENDER Integrated Delivery System, a drug-eluting coronary stent-on-a-wire designed to facilitate transradial interventions, and the DIRECT Rapid Exchange System, which enhances direct stenting and high-pressure post-dilatations. Both systems utilize proprietary technologies to improve stent deliverability, reduce the need for additional guide wires and balloons, and ultimately enhance patient outcomes while minimizing procedure costs and risks.

Akarna Therapeutics

Series B in 2016
Akarna Therapeutics Ltd., a biopharmaceutical company, develops small molecule therapeutics that target inflammatory and fibrotic diseases. It offers non-bile acid FXR agonist, a therapeutic for the treatment of nonalcoholic steatohepatitis and fatty-liver diseases. The company was incorporated in 2014 and is based in Cambridge, United Kingdom with an additional office in San Diego, California. As of August 26, 2016, Akarna Therapeutics Ltd. operates as a subsidiary of Allergan plc.

Ovizio

Venture Round in 2015
Ovizio Imaging Systems NV/SA specializes in the development of digital holographic interferometric microscopy products, creating advanced 4D microscopic imaging devices and software. Founded in 2009 and headquartered in Brussels, Belgium, the company offers a range of devices, including the oLine 4D, which requires no specific sample preparation and compensates for sample imperfections; the iLine 4D, designed for various applications such as flow monitoring and cell culture observation; and various specialized instruments like ILine F for real-time monitoring of suspension cell cultures and iLine M for assessing cell confluence in multi-layer vessels. Ovizio also provides OsOne software for the visualization, analysis, and archiving of captured images, alongside QMod, which integrates holographic and fluorescence microscopy. Its products are widely utilized by scientists in pharmaceutical and biotechnology research and development, facilitating advancements in automated cell culture monitoring and analysis.

Fuzzy Logix

Series A in 2015
Fuzzy Logix in-database analytics solutions you’re not bound by the constraints of traditional analytics. By eliminating the need for data extraction, middle-tier analytics servers and redundant data storage, our products allow you to process your analytics within the database and make massive time, cost and resource savings.

EXTEN Technologies

Series B in 2015
EXTEN provides high-performance storage software to hyperscale data centers. EXTEN’s agile, reliable, and scalable solution is well suited for the most demanding high-performance, low-latency workloads where needs are highly variable and unpredictable including e-commerce, real-time analytics, and video processing, financial and trading applications, transaction processing, and buffering workloads with large-scale file systems. Founded in 2012, EXTEN Technologies is a pioneer in ultra-high-performance NVMe over Fabrics storage software applications. EXTEN is venture capital funded and is based in Austin, Texas.

Novadip Biosciences

Series A in 2015
Novadip Biosciences SA is a biopharmaceutical company that develops process and distribution platform for tissue regeneration. It focuses on autologous cell therapies for critical size tissue reconstruction; allogeneic therapeutics for smaller and prevalent tissue defects; and miRNA/exosome-based therapeutics for systemic tissue and other diseases. The company was founded in 2013 and is based in Mont-Saint-Guibert, Belgium.

Vorago Technologies

Series D in 2015
Vorago Technologies Inc. is a privately held fabless semiconductor company based in Austin, Texas, that specializes in the design, manufacturing, and testing of radiation-hardened and extreme temperature-hardened integrated circuit (IC) components. Founded in 2004 and formerly known as Silicon Space Technology, Vorago develops high-density SRAMs and microcontrollers tailored for automotive, industrial, military, aerospace, and networking applications. The company utilizes its patented HARDSIL technology to enhance the radiation and temperature endurance of ICs without requiring redesigns, making it scalable across various CMOS process generations. In addition to memory solutions like 16Mb asynchronous and 8Mb dual-port synchronous SRAMs, Vorago offers custom application-specific integrated circuit (ASIC) design services leveraging its hardened Metal Programmable System On Chip (MPSoC) platform. This innovative approach provides a reliable alternative to traditional high-reliability methods, ensuring that integrated circuits can perform effectively in extreme environments.

Ralexar Therapeutics

Series A in 2015
Ralexar Therapeutics, Inc. is a biopharmaceutical company focused on developing and manufacturing topical and systemic therapies that utilize Liver X Receptor (LXR) modulators. The company targets a range of cutaneous inflammatory disorders, with a particular emphasis on atopic dermatitis. Founded in 2013 and headquartered in Wayne, Pennsylvania, Ralexar is known for its clinical development of ALX-101, a topical therapy designed to improve treatment outcomes for patients with dermatological conditions. Originally established as Alexar Therapeutics, the company rebranded in March 2016 and operates as a subsidiary of NeXeption, LLC.

PerceptiMed

Venture Round in 2015
PerceptiMed’s groundbreaking VeriFill™ technology reduces the margin of human error in prescription pill dispensing within retail pharmacies, long-term care facilities and hospitals. Its IdentRx™suite of medication verification and dispensing products are fast, accurate and cost-effective -- providing 100% verification of drug, dosage and manufacturer for every pill, every time.

Vaultive

Series B in 2015
Vaultive is a provider of cloud data encryption solutions designed to enhance data security for businesses transitioning to cloud environments. By employing encryption in use technology, Vaultive enables companies to maintain control and ownership of their sensitive data, regardless of its location. Customers retain the encryption keys, which allows them to utilize essential cloud applications while ensuring compliance with governance and security requirements. This approach mitigates risks associated with data breaches and unauthorized access, making Vaultive a valuable partner for organizations seeking to safeguard their information in the cloud.

Cambridge Epigenetix

Series A in 2014
Cambridge Epigenetix Limited, a bioscience company, provides epigenetic tools. It offers TrueMethyl oxidative bisulfite sequencing (oxBS-Seq), a technology that enables single-base resolution sequencing of hydroxymethyl cytosine (5hmC) and methylcytosine (5mC), as well as provides the analysis of the DNA methylome. The company’s products include TrueMethyl 6 and TrueMethyl 24 kits that enable quantitative measurement of 5hmC and 5mC, single-base resolution of methylation and hydroxymethylation analysis, and confirmation of the location of unmethylated cytosines. It offers its products through third party vendors, as well as online to business customers in the United Kingdom and internationally. Cambridge Epigenetix Limited was founded in 2012 and is based in Babraham, United Kingdom.

Kateeva

Series D in 2014
Kateeva is focused on advancing OLED production technology through its innovative inkjet printing manufacturing equipment. This approach enables the production of flexible and large-size OLEDs at high volumes, resulting in longer lifetimes, higher yields, and reduced production costs. Kateeva's technology represents a significant breakthrough, as it is the first economically viable method for the mass production of OLEDs using printing techniques. This innovation is poised to transform the display industry, making large OLED televisions and lightweight wearable devices more accessible to consumers. By enhancing the efficiency and cost-effectiveness of OLED manufacturing, Kateeva aims to drive the next wave of advancements in consumer electronics.

Svelte Medical Systems

Venture Round in 2014
Svelte Medical Systems, Inc. is a privately held company that specializes in the design and development of innovative balloon-expandable stents for patients undergoing percutaneous coronary interventions to treat atherosclerosis. Founded in 2007, the company is based in New Providence, New Jersey, and aims to address critical clinical issues in the coronary stent market, which is valued at approximately $5 billion. Svelte offers two primary products: the SLENDER Integrated Delivery System, a drug-eluting coronary stent-on-a-wire designed to facilitate transradial interventions, and the DIRECT Rapid Exchange System, which enhances direct stenting and high-pressure post-dilatations. Both systems utilize proprietary technologies to improve stent deliverability, reduce the need for additional guide wires and balloons, and ultimately enhance patient outcomes while minimizing procedure costs and risks.

TigerConnect

Series B in 2014
TigerConnect is a healthcare communication platform designed to enhance collaboration among healthcare professionals, patients, and care providers. Founded in 2010 and based in Santa Monica, California, the company offers real-time mobile messaging that combines a user-friendly experience with robust security and privacy features. Trusted by over 4,000 healthcare organizations, TigerConnect processes more than 10 million messages daily and boasts a 99.99% uptime. The platform facilitates effective communication and workflow integration with critical hospital systems, ultimately aiming to improve productivity, reduce costs, and enhance patient outcomes. TigerConnect's commitment to client success is evident in its comprehensive support services, which assist organizations in optimizing communication workflows.

NeXeption

Series A in 2014
NeXeption, LLC is a biopharmaceutical management company that brings together product opportunities, management expertise and the necessary funding to reach compelling partnership milestones. The NeXeption management team has a proven track record in raising capital, operating development stage companies and forming strategic partnerships to advance products for the benefit of patients.

Ario Pharma

Seed Round in 2013
Ario Pharma ltd focusses on the development of drugs for the treatment of respiratory indications. Ario is about to evaluate the anti-tussive properties of XEN-D0501, a potential best-in-class TRPV1 inhibitor, in two Phase 2 clinical trials that will read out in 2014. The company is managed by a highly experienced development team and supported by world-renowned KOLs in respiratory disease.

BrightVolt

Series A in 2013
BrightVolt, Inc. is engaged in the design, development, and scale manufacturing of ultra thin film batteries to power various Internet connected devices, such as medical patches, sensor labels, and power cards. It also develops custom solid state thin film batteries and power solutions for client’s IoT devices; Flexion solid state thin film lithium polymer batteries; and thin micro electronics. The company’s products are sold in the United States and internationally. BrightVolt, Inc. was formerly known as Solicore, Inc. The company was incorporated in 1998 and is based in Redmond, Washington.

Dezima Pharma

Venture Round in 2013
Dezima Pharma B.V. is a biopharmaceutical company based in Naarden, the Netherlands, established in 2012. The company focuses on developing protein-based compounds aimed at treating cardiovascular diseases associated with dyslipidemia. By targeting this specific patient population, Dezima Pharma seeks to address significant medical needs in the management of cholesterol-related conditions.

Resolve Therapeutics

Series B in 2012
Resolve Therapeutics is a private biotechnology company that is dedicated to the goal of improving the lives of patients suffering from lupus. They are focused on the advancement their exciting, novel biologic compound, RSLV-125 from preclinical research through a phase IIa clinical trial. The company is based on the pioneering discoveries made by Dr. Keith Elkon and Dr. Jeff Ledbetter in their laboratories at the University of Washington School of Medicine.

Achronix Semiconductor

Venture Round in 2012
Achronix Semiconductor Corp., founded in 2004 and headquartered in Santa Clara, California, specializes in high-density and high-performance application-targeted field programmable gate arrays (FPGAs). The company offers a range of products, including Speedster®22i HD devices, which feature up to 1.7 million effective look-up tables (LUTs) and 138 megabits of embedded RAM, and Speedster22i HP devices, which utilize picoPIPE architecture and provide up to 590 thousand effective LUTs with 64 megabits of embedded RAM. Achronix's Speedcore eFPGA IP allows integration into customer system-on-chips (SoCs) for compute and network acceleration. Additionally, the Achronix CAD Environment (ACE) supports FPGA design, while the HD1000 development board is optimized for networking and communication sub-systems. Achronix serves diverse markets, including networking, optical/telecom, high-performance computing, test and measurement, and military and security. Its products are distributed across North America, Europe, Israel, China, and Russia, with research and development facilities also in Bangalore, India.

Juventas Therapeutics

Series B in 2012
Juventas Therapeutics, Inc., a clinical stage biotechnology company, develops non-viral gene therapies that activate natural processes to repair the body. The company focuses on treatment of non-healing wounds in patients with advanced peripheral artery disease. It offers JVS-100, a non-viral gene therapy that expresses stromal cell-derived factor-1 or SDF-1, a naturally occurring signaling protein that has been shown to recruit the body’s own stem cells and promote tissue repair in a range of disease states. Juventas Therapeutics, Inc. was formerly known as AcelleRX Therapeutics, Inc. and changed its name to Juventas Therapeutics, Inc. in April 2009. The company was founded in 2007 and is based in Cleveland, Ohio.

Vaultive

Series A in 2012
Vaultive is a provider of cloud data encryption solutions designed to enhance data security for businesses transitioning to cloud environments. By employing encryption in use technology, Vaultive enables companies to maintain control and ownership of their sensitive data, regardless of its location. Customers retain the encryption keys, which allows them to utilize essential cloud applications while ensuring compliance with governance and security requirements. This approach mitigates risks associated with data breaches and unauthorized access, making Vaultive a valuable partner for organizations seeking to safeguard their information in the cloud.

TigerConnect

Series A in 2012
TigerConnect is a healthcare communication platform designed to enhance collaboration among healthcare professionals, patients, and care providers. Founded in 2010 and based in Santa Monica, California, the company offers real-time mobile messaging that combines a user-friendly experience with robust security and privacy features. Trusted by over 4,000 healthcare organizations, TigerConnect processes more than 10 million messages daily and boasts a 99.99% uptime. The platform facilitates effective communication and workflow integration with critical hospital systems, ultimately aiming to improve productivity, reduce costs, and enhance patient outcomes. TigerConnect's commitment to client success is evident in its comprehensive support services, which assist organizations in optimizing communication workflows.

Oxyrane UK

Series D in 2011
Oxyrane UK Limited, a biopharmaceutical company, develops novel and biosuperior enzyme replacement therapies for the treatment of lysosomal storage diseases. It provides human lysosomal enzymes that enable clinically effective enzyme uptake and localization using its glycoengineered yeast platform. The company was founded in 2006 and is based in Manchester, United Kingdom. It has locations in Gent, Belgium; and Burlington, Massachusetts.

Resolve Therapeutics

Series A in 2011
Resolve Therapeutics is a private biotechnology company that is dedicated to the goal of improving the lives of patients suffering from lupus. They are focused on the advancement their exciting, novel biologic compound, RSLV-125 from preclinical research through a phase IIa clinical trial. The company is based on the pioneering discoveries made by Dr. Keith Elkon and Dr. Jeff Ledbetter in their laboratories at the University of Washington School of Medicine.

Lightwire

Venture Round in 2011
Lightwire’s mission is to deliver efficient integration of optical and electrical solutions which will power the next generation of high speed interconnects using CMOS photonics technology.

Celleration

Series E in 2011
Celleration Inc. develops and commercializes therapeutic ultrasound healing technologies in the United States. It offers MIST Therapy, a noncontact and low frequency ultrasound solution delivered through a saline mist to the wound bed. The company serves patients, medical professionals, and payers. Celleration Inc. was formerly known as Advanced Medical Applications, Inc. The company was founded in 1999 and is based in Eden Prairie, Minnesota. As of May 29, 2015, Celleration, Inc. operates as a subsidiary of Alliqua BioMedical, Inc.

ProterixBio

Series D in 2010
ProterixBio, Inc. specializes in developing disease management platforms aimed at improving patient outcomes in chronic respiratory diseases, particularly chronic obstructive pulmonary disease, cystic fibrosis, and idiopathic pulmonary fibrosis. The company utilizes its proprietary ViBE platform and Acoustic Membrane MicroParticle (AMMP) assays to facilitate the precise analysis of proteins in various biological samples, including blood and sputum. The AMMP technology employs a non-optical, homogeneous assay approach, which enhances the sensitivity and specificity of traditional reagents through the integration of biological capture strategies and advanced acoustic sensors. By providing real-time biological assessments of a patient's disease state, ProterixBio's products support healthcare providers in managing chronic conditions more effectively, reducing the need for hospitalizations, and ultimately lowering healthcare costs. Founded in 2002 and based in Billerica, Massachusetts, ProterixBio was previously known as BioScale, Inc. before rebranding in May 2016.

Seahorse Bioscience

Series D in 2010
Seahorse Bioscience provides analytical instruments, biomanufacturing systems and consumable labware products for biological research and drug discovery. The company's customers include scientists at academic institutions, pharmaceutical and biotech organizations, as well as OEM manufacturers of assay kits and lab instruments suppliers.

BioVex

Venture Round in 2009
BioVex is a biotechnology company focused on the development and commercialization of biological treatments for cancer and the prevention of infectious disease. Their cancer program, OncoVEXGM-CSF, is a oncolytic vaccine or cancer destroying virus technology that works by replicating and spreading within solid tumors, causing the death of cancer cells while leaving surrounding healthy cells unharmed. The attenuated virus has also been constructed to induce a powerful systemic anti tumor immune response. OncoVEXGM-CSF has now been tested in >110 patients in a broad range of solid tumors including melanoma, head & neck cancer, breast cancer and pancreatic cancer. Both the direct cell killing and systemic immune mediated mechanisms of action of OncoVEX have been clearly validated in the clinic; OncoVEX routinely destroys tumors it is directly injected into and has led to overall disease responses in multiple patients in Phase II testing. Tumors resolved through OncoVEX treatment have not been known to recur.

Seahorse Bioscience

Series D in 2009
Seahorse Bioscience provides analytical instruments, biomanufacturing systems and consumable labware products for biological research and drug discovery. The company's customers include scientists at academic institutions, pharmaceutical and biotech organizations, as well as OEM manufacturers of assay kits and lab instruments suppliers.

Achronix Semiconductor

Series B in 2008
Achronix Semiconductor Corp., founded in 2004 and headquartered in Santa Clara, California, specializes in high-density and high-performance application-targeted field programmable gate arrays (FPGAs). The company offers a range of products, including Speedster®22i HD devices, which feature up to 1.7 million effective look-up tables (LUTs) and 138 megabits of embedded RAM, and Speedster22i HP devices, which utilize picoPIPE architecture and provide up to 590 thousand effective LUTs with 64 megabits of embedded RAM. Achronix's Speedcore eFPGA IP allows integration into customer system-on-chips (SoCs) for compute and network acceleration. Additionally, the Achronix CAD Environment (ACE) supports FPGA design, while the HD1000 development board is optimized for networking and communication sub-systems. Achronix serves diverse markets, including networking, optical/telecom, high-performance computing, test and measurement, and military and security. Its products are distributed across North America, Europe, Israel, China, and Russia, with research and development facilities also in Bangalore, India.

Celleration

Series D in 2008
Celleration Inc. develops and commercializes therapeutic ultrasound healing technologies in the United States. It offers MIST Therapy, a noncontact and low frequency ultrasound solution delivered through a saline mist to the wound bed. The company serves patients, medical professionals, and payers. Celleration Inc. was formerly known as Advanced Medical Applications, Inc. The company was founded in 1999 and is based in Eden Prairie, Minnesota. As of May 29, 2015, Celleration, Inc. operates as a subsidiary of Alliqua BioMedical, Inc.

TherOx

Venture Round in 2008
TherOx, Inc. develops and manufactures dissolved oxygen delivery systems to improve the standard of care in heart attack treatments. It provides SSO2 therapy consists of TherOx DownStream system, a mobile hardware device that interfaces with the TherOx DownStream Cartridge and Console that controls cartridge operation wherein SSO2 solution is created and mixed with the patients blood to create superoxygenated blood for delivery to the coronary arteries. The company was founded in 1994 and is based in Irvine, California. As of June 18, 2019, TherOx, Inc. operates as a subsidiary of ZOLL Medical Corporation.

BioVex

Series E in 2007
BioVex is a biotechnology company focused on the development and commercialization of biological treatments for cancer and the prevention of infectious disease. Their cancer program, OncoVEXGM-CSF, is a oncolytic vaccine or cancer destroying virus technology that works by replicating and spreading within solid tumors, causing the death of cancer cells while leaving surrounding healthy cells unharmed. The attenuated virus has also been constructed to induce a powerful systemic anti tumor immune response. OncoVEXGM-CSF has now been tested in >110 patients in a broad range of solid tumors including melanoma, head & neck cancer, breast cancer and pancreatic cancer. Both the direct cell killing and systemic immune mediated mechanisms of action of OncoVEX have been clearly validated in the clinic; OncoVEX routinely destroys tumors it is directly injected into and has led to overall disease responses in multiple patients in Phase II testing. Tumors resolved through OncoVEX treatment have not been known to recur.

Ikonisys

Series E in 2007
Ikonisys, Inc. specializes in designing and manufacturing medical diagnostic products aimed at cancer diagnosis and genetic disorder detection in the United States and Europe. The company offers a range of innovative products, including the Ikoniscope Robotic Microscope, which automates slide handling, scanning, and real-time image analysis to minimize human error in testing. Key applications include oncoFISH bladder for analyzing urine samples, oncoFISH her2 for assessing HER2 status in breast tissue, and oncoFISH PTEN for detecting PTEN gene deletions in prostate biopsies. Additionally, Ikonisys provides FISH scanning applications for both cell suspensions and various tissue sections, along with the IkoniWAN Gateway, a remote access solution for digital microscopy systems. Founded in 1999 and headquartered in New Haven, Connecticut, Ikonisys is committed to advancing diagnostic medicine through early and non-invasive disease detection, thereby enhancing patient management.

FlowCardia

Series C in 2007
FlowCardia, Inc. is a medical device company founded in 2002 to design and develop a portfolio of innovative, catheter-based technologies to facilitate guidewire crossing of totally occluded coronary and peripheral arteries. Chronic Total Occlusions (CTOs) are considered one of the last major clinical challenges in interventional therapy. The historic absence of safe and effective CTO recanalization devices is a major reason a large number of patients are still referred to coronary and peripheral bypass surgery and lower limb amputation.

BioProcessors

Series C in 2007
BioProcessors is an online platform that assists its clients in the development of drugs. BioProcessors was launched in 2000 and is based in California.

Xoft

Series D in 2007
Xoft, Inc. develops electronic brachytherapy (eBx) systems for radiation oncology applications. It offers Axxent Controller that utilizes a miniaturized high dose rate (HDR) X-ray source to apply radiation directly to the cancerous tumor bed. The company also provides Axxent balloon applicator, a treatment solution for accelerated partial breast irradiation; Axxent vaginal applicator that enables radiation oncologists to perform vaginal brachytherapy; and Axxent surface applicator that enables radiation oncologists to treat surface lesions. In addition, it offers accessories, such as physics accessory kits, personnel protective shields, procedure accessory packs, patient care kits, applicator clamp and base plates, and vacuum pumps, as well as FlexiShield, which drapes over the patient treatment area to reduce radiation transmission to nearby healthy tissue and organs. The company's products are used to treat early stage breast cancer, skin cancer, and endometrial cancer. It offers its products through physicians and distributors in Europe. Xoft, Inc. was formerly known as Xoft microTube, Inc. and changed its name in September 2004. The company was founded in 1998 and is based in Sunnyvale, California.

Ception Therapeutics

Series C in 2007
Ception Therapeutics is a biopharmaceutical company focused on the discovery and development of novel products to address areas of unmet medical need. Ception was founded by experienced pharmaceutical executives in order to develop and commercialize therapeutics in areas of significant unmet medical need.

Achronix Semiconductor

Series A in 2007
Achronix Semiconductor Corp., founded in 2004 and headquartered in Santa Clara, California, specializes in high-density and high-performance application-targeted field programmable gate arrays (FPGAs). The company offers a range of products, including Speedster®22i HD devices, which feature up to 1.7 million effective look-up tables (LUTs) and 138 megabits of embedded RAM, and Speedster22i HP devices, which utilize picoPIPE architecture and provide up to 590 thousand effective LUTs with 64 megabits of embedded RAM. Achronix's Speedcore eFPGA IP allows integration into customer system-on-chips (SoCs) for compute and network acceleration. Additionally, the Achronix CAD Environment (ACE) supports FPGA design, while the HD1000 development board is optimized for networking and communication sub-systems. Achronix serves diverse markets, including networking, optical/telecom, high-performance computing, test and measurement, and military and security. Its products are distributed across North America, Europe, Israel, China, and Russia, with research and development facilities also in Bangalore, India.

BioProcessors

Series C in 2006
BioProcessors is an online platform that assists its clients in the development of drugs. BioProcessors was launched in 2000 and is based in California.

Ikonisys

Series D in 2006
Ikonisys, Inc. specializes in designing and manufacturing medical diagnostic products aimed at cancer diagnosis and genetic disorder detection in the United States and Europe. The company offers a range of innovative products, including the Ikoniscope Robotic Microscope, which automates slide handling, scanning, and real-time image analysis to minimize human error in testing. Key applications include oncoFISH bladder for analyzing urine samples, oncoFISH her2 for assessing HER2 status in breast tissue, and oncoFISH PTEN for detecting PTEN gene deletions in prostate biopsies. Additionally, Ikonisys provides FISH scanning applications for both cell suspensions and various tissue sections, along with the IkoniWAN Gateway, a remote access solution for digital microscopy systems. Founded in 1999 and headquartered in New Haven, Connecticut, Ikonisys is committed to advancing diagnostic medicine through early and non-invasive disease detection, thereby enhancing patient management.

Light Sciences Oncology

Series A in 2005
Light Sciences Oncology, Inc. develops and manufactures talaporfin sodium for the treatment of tumors and other indications in patients. The company also offers drug activator, an LED based single use disposable device that provides a fixed light dose. Its drug is used for the treatment of patients with hepatocellular carcinoma, metastatic colorectal cancer, and benign prostatic hyperplasia and enlargement of the prostate. The company was founded in 1994 and is based in Bellevue, Washington.

TherOx

Venture Round in 2005
TherOx, Inc. develops and manufactures dissolved oxygen delivery systems to improve the standard of care in heart attack treatments. It provides SSO2 therapy consists of TherOx DownStream system, a mobile hardware device that interfaces with the TherOx DownStream Cartridge and Console that controls cartridge operation wherein SSO2 solution is created and mixed with the patients blood to create superoxygenated blood for delivery to the coronary arteries. The company was founded in 1994 and is based in Irvine, California. As of June 18, 2019, TherOx, Inc. operates as a subsidiary of ZOLL Medical Corporation.

BioProcessors

Series B in 2003
BioProcessors is an online platform that assists its clients in the development of drugs. BioProcessors was launched in 2000 and is based in California.
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