Rob Capone

Venture Partner

Gary Curtis

Venture Partner

Alex Efron

Associate

Paul Grossman

Partner

Rob C. Hart

Partner

Alexander C. Herzick

Partner

Deval A. Lashkari

Senior Partner

J. Matthew Mackowski

Chairman, MD

Thomas A. Raffin

Venture Partner

Robert Shepler

Partner Emeritus

Jeanette M. Welsh

Partner, COO

45 past transactions

Mosaic Biosciences, Inc.

Venture Round in 2022
Mosaic Biosciences, Inc. develops biomaterials for tissue engineering applications. Its technology platform provides biomaterial for various medical applications, such as drug delivery, regenerative medicine, stem cell therapies, and sealants and adhesion barriers. Mosaic Biosciences, Inc. has a strategic collaboration with Catalyst Biosciences. The company was incorporated in 2009 and is based in Boulder, Colorado.

Carterra, Inc.

Venture Round in 2020
Carterra provides biotechnology solutions that develop and commercialize novel micro-array deposition technologies. The company provides users with instruments and services, which enable multiplexing on planar array surfaces. It also offers Continuous Flow Microspotter (CFM), which includes an array printing instrument and a microfluidic print head. Its products include spot CFM printhead, which uses a network of microchannels to deposit samples at one time in a block; and CFM instrument, which uses built-in sensors and pumps to control the flow within the CFM print head. It was founded in 2005 and headquartered in Salt Lake City, Utah.

Estech

Venture Round in 2008
ESTECH is a privately held medical device manufacturing and distribution company located in San Ramon, California. The company was founded by Arthur and Raymond Bertolero in 1996 with an emphasis on least invasive products for cardiac surgery. ESTECH has worldwide distribution and has consistently attracted goal oriented professionals who represent the brightest minds in the medical device industry. The in-depth professional experience and tireless dedication of the ESTECH Team has allowed the company to achieve rapid and sustained success in this highly competitive environment. ESTECH is proud of each employee from every department and thanks them for their contribution and support.

AngioScore

Series E in 2007
AngioScore Inc. develops, manufactures and markets the AngioSculpt Scoring Balloon Catheter for both the coronary and peripheral interventional markets. Designed specifically to address the limitations of conventional angioplasty balloon catheters, AngioSculpt combines a semi-compliant balloon with an innovative nitinol scoring element.

Carterra, Inc.

Private Placement in 2018
Carterra provides biotechnology solutions that develop and commercialize novel micro-array deposition technologies. The company provides users with instruments and services, which enable multiplexing on planar array surfaces. It also offers Continuous Flow Microspotter (CFM), which includes an array printing instrument and a microfluidic print head. Its products include spot CFM printhead, which uses a network of microchannels to deposit samples at one time in a block; and CFM instrument, which uses built-in sensors and pumps to control the flow within the CFM print head. It was founded in 2005 and headquartered in Salt Lake City, Utah.

Estech

Series B in 2003
ESTECH is a privately held medical device manufacturing and distribution company located in San Ramon, California. The company was founded by Arthur and Raymond Bertolero in 1996 with an emphasis on least invasive products for cardiac surgery. ESTECH has worldwide distribution and has consistently attracted goal oriented professionals who represent the brightest minds in the medical device industry. The in-depth professional experience and tireless dedication of the ESTECH Team has allowed the company to achieve rapid and sustained success in this highly competitive environment. ESTECH is proud of each employee from every department and thanks them for their contribution and support.

Specific Diagnostics, LLC

Private Placement in 2019
Specific Diagnostics, LLC develops solutions for the detection, identification, and antibiotic susceptibility testing. It offers Specific Reveal system that provides antibiotic susceptibility results that allows clinics to deploy specific solutions. Specific Diagnostics, LLC was founded in 2011 and is headquartered in West Palm Beach, Florida.

Dynex Technologies, Inc.

Acquisition in 2017
Dynex Technologies, Inc. designs, engineers, manufactures, and distributes ELISA microplate workstations, laboratory instruments, and associated consumables and accessories. The company also offers technical support services. It provides its products through distributors in the United States, Canada, Mexico and South America, Asia, Europe, the Middle East and Africa, and internationally, as well as online. Dynex Technologies, Inc. was formerly known as Dynatech Laboratories, Inc. and changed its name to Dynex Technologies, Inc. in 1996. The company was founded in 1952 and is based in Chantilly, Virginia. Dynex Technologies, Inc. is a former subsidiary of Magellan Diagnostics, Inc.

Asuragen

Series A in 2006
Asuragen is a fully integrated diagnostics company focused on molecular oncology and early detection of cancer, with an emphasis on microRNA. Asuragen's current diagnostics product portfolio consists of Signature® Genetic and Oncology Testing products, as well as industry leading controls and standards engineered using its patented Armored RNA® technology. In addition to its diagnostics products, Asuragen offers GLP testing services and an established cGMP manufacturing facility that allow it to span the spectrum of discovery, testing, production and commercialization.

Nivagen Pharmaceuticals, Inc.

Private Placement in 2020
Nivagen Pharmaceuticals, Inc. engages in the development, acquisition, and sales of generic prescription drugs and over the counter products for the North American market. The company sells its products through chain drug stores, regional wholesalers, mass merchandisers, hospitals, GPOs, mail order pharmacies, and other buying groups. Nivagen Pharmaceuticals, Inc. was incorporated in 2009 and is based in Sacramento, California.

Carterra, Inc.

Venture Round in 2020
Carterra provides biotechnology solutions that develop and commercialize novel micro-array deposition technologies. The company provides users with instruments and services, which enable multiplexing on planar array surfaces. It also offers Continuous Flow Microspotter (CFM), which includes an array printing instrument and a microfluidic print head. Its products include spot CFM printhead, which uses a network of microchannels to deposit samples at one time in a block; and CFM instrument, which uses built-in sensors and pumps to control the flow within the CFM print head. It was founded in 2005 and headquartered in Salt Lake City, Utah.

TrakCel Ltd.

Venture Round in 2016
TrakCel's proven technology integrates and orchestrates every aspect of Autologous and Allogeneic supply chains in a scalable, compliant and validated technology platform.

Althea Technologies

Series C in 2007
Althea Technologies, located in San Diego, CA, is a contract development and manufacturing organization that specializes in cGMP manufacturing, analytical development, aseptic filling into vials & syringes, and protein delivery technology for recombinant protein and parenteral products. In a single location, Althea has the capacity to meet your early-stage and commercial requirements.

AltheaDx, Inc.

Series A in 2010
AltheaDx, Inc. provides molecular diagnostics and PCR-based services. It offers molecular biomarker discovery, assay development, assay validation, and prospective/retrospective clinical trial testing services. The company also provides gene expression and genotyping analysis for pre-clinical and clinical applications. In addition, it offers discovery services, such as microarray analysis, real-time PCR, next-gen sequencing, quantitative PCR, mutation scanning, data analysis, race assay, and therapeutic siRNA; and diagnostic development services.

Carterra, Inc.

Venture Round in 2018
Carterra provides biotechnology solutions that develop and commercialize novel micro-array deposition technologies. The company provides users with instruments and services, which enable multiplexing on planar array surfaces. It also offers Continuous Flow Microspotter (CFM), which includes an array printing instrument and a microfluidic print head. Its products include spot CFM printhead, which uses a network of microchannels to deposit samples at one time in a block; and CFM instrument, which uses built-in sensors and pumps to control the flow within the CFM print head. It was founded in 2005 and headquartered in Salt Lake City, Utah.

AngioScore

Series D in 2006
AngioScore Inc. develops, manufactures and markets the AngioSculpt Scoring Balloon Catheter for both the coronary and peripheral interventional markets. Designed specifically to address the limitations of conventional angioplasty balloon catheters, AngioSculpt combines a semi-compliant balloon with an innovative nitinol scoring element.

Precision Nanosystems, Inc.

Private Placement in 2018
Precision Nanosystems, Inc. develops tools and processes for the development and manufacture of nanoparticles for use as medicines and in medical research. It offers NanoAssemblr benchtop instrument for prototyping of nanoparticles, as well as for the development of nanoparticle based drugs delivering RNA, small-molecule, and protein therapeutics. The company also provides Neuro9Kit for the study of gene function in neurons and glia cells, as well as potent delivery to primary cells; Test9Kit for the study of gene function in various cell types; Hepato9Kit for the study of gene function in the liver; and Ignite for clinical manufacturing. In addition, it provides instruments, reagents, and services to life sciences researchers through its distributors in Canada and internationally. Precision Nanosystems, Inc. has a strategic partnership with Sirnaomics Inc. Precision Nanosystems, Inc. was incorporated in 2010 and is based in Vancouver, Canada.

Emerging Therapy Solutions

Venture Round in 2019
Emerging Therapy Solutions, Inc. engages in the outsourced management of cell and gene therapy treatments for health care payers. It offers services ranging from patient management to data collection, analysis, reporting, and claims administration. The company was incorporated in 2018 and is based in Bloomington, Minnesota.

Precision NanoSystem

Series B in 2018
Precision Nanosystems develops tools and processes for the development and manufacture of nanoparticles for use as medicines and in medical research. It offers NanoAssemblr benchtop instrument for prototyping of nanoparticles, as well as for the development of nanoparticle-based drugs delivering RNA, small-molecule, and protein therapeutics. The company also provides Neuro9Kit for the study of gene function in neurons and glial cells, as well as potent delivery to primary cells; Test9Kit for the study of gene function in various cell types; and Hepato9Kit for the study of gene function in the liver. In addition, it provides instruments, reagents, and services to the life sciences researchers.

PneumRx

Series B in 2007
PneumRx, Inc., a start-up medical device company, develops minimally invasive treatments for emphysema patients. The company develops RePneu Lung Volume Reduction Coil, an investigational device for treating emphysema patients. PneumRx, Inc. was founded in 2004 and is based in Mountain View, California.

Asuragen

Series B in 2007
Asuragen is a fully integrated diagnostics company focused on molecular oncology and early detection of cancer, with an emphasis on microRNA. Asuragen's current diagnostics product portfolio consists of Signature® Genetic and Oncology Testing products, as well as industry leading controls and standards engineered using its patented Armored RNA® technology. In addition to its diagnostics products, Asuragen offers GLP testing services and an established cGMP manufacturing facility that allow it to span the spectrum of discovery, testing, production and commercialization.

Freedom Innovations LLC.

Funding Round in 2008
Freedom Innovations LLC is a company that offers lower limb solutions for low to high mobility users.

Nivagen Pharmaceuticals, Inc.

Venture Round in 2020
Nivagen Pharmaceuticals, Inc. engages in the development, acquisition, and sales of generic prescription drugs and over the counter products for the North American market. The company sells its products through chain drug stores, regional wholesalers, mass merchandisers, hospitals, GPOs, mail order pharmacies, and other buying groups. Nivagen Pharmaceuticals, Inc. was incorporated in 2009 and is based in Sacramento, California.

Accumetrics

Series B in 2004
Accumetrics is a privately-held company that develops, manufactures, and markets the VerifyNow System, a comprehensive suite of assays for the assessment of platelet function. Accumetrics, based in San Diego, California, was founded in 1996, sold to Radiometer in 2000, and repurchased by company management and investors in 2003.

Precision NanoSystem

Series A in 2015
Precision Nanosystems develops tools and processes for the development and manufacture of nanoparticles for use as medicines and in medical research. It offers NanoAssemblr benchtop instrument for prototyping of nanoparticles, as well as for the development of nanoparticle-based drugs delivering RNA, small-molecule, and protein therapeutics. The company also provides Neuro9Kit for the study of gene function in neurons and glial cells, as well as potent delivery to primary cells; Test9Kit for the study of gene function in various cell types; and Hepato9Kit for the study of gene function in the liver. In addition, it provides instruments, reagents, and services to the life sciences researchers.

Cell Microsystems

Venture Round in 2021
Cell Microsystems is an early growth stage company that develops, manufactures, and markets innovative products for single cell biology. The Company’s proprietary CellRaft™ Technology enables high-efficiency sorting and isolation of single cells under standard culture conditions resulting in unperturbed phenotypes and high viability. Coupled with the Company’s automated imaging platform, a user can select a cell in real-time and ‘track and trace’ that cell through imaging, collection and downstream analysis. By sorting during real-time imaging, no cells are wasted enabling single cell isolation from even small, precious samples. The CellRaft Technology offers scalable solutions making cell separation technology available for every lab.

Akoya Biosciences, Inc.

Private Placement in 2019
Akoya Biosciences is developing a novel high-parameter tissue analysis platform, at an order of magnitude beyond what is currently possible. Their CODEX (TM) (CO-Detection by indEXing) system enables deep proteomic profiling all on your existing microscope​. If you are a scientist or software engineer interested in revolutionizing the science of imaging, then Akoya is the place for you.

Nimble Therapeutics

Series A in 2019
Nimble Therapeutics is a developer of a drug discovery platform intended to bring the power of massively parallel chemical synthesis to drug discovery. The company uses its unique maskless chemical synthesis platform to synthesize and systematically discover novel medicines in a variety of therapeutic areas, providing customers aid in the empirical optimization of molecules with more favorable drug-like properties.

MEDPRICER.COM, INC.

Venture Round in 2017
MEDPRICER.COM, INC. develops purchased services cost management solution for the healthcare industry. The company owns and operates mSource, a purchased services cost management software platform that empowers healthcare providers to discover, organize, benchmark, and manage their service provider spending. It also offers precision benchmark reports, project management, and advisory services. The company was founded in 2004 and is based in Guilford, Connecticut with an additional office in Walnut Creek, California. As of October 28, 2019, MEDPRICER.COM, INC. operates as a subsidiary of Premier, Inc.

Aquaro Histology

Series A in 2017
Aquaro Histology, Inc. engages in manufacturing of a section mounting system to streamline the histology workflow. The company's product automates the placement of paraffin-embedded tissue sections onto slides. It's product is used in laboratories to enhance patient diagnosis and care. The company was founded in 2017 and is headquartered in Ann Arbor, Michigan.

Estech

Venture Round in 2009
ESTECH is a privately held medical device manufacturing and distribution company located in San Ramon, California. The company was founded by Arthur and Raymond Bertolero in 1996 with an emphasis on least invasive products for cardiac surgery. ESTECH has worldwide distribution and has consistently attracted goal oriented professionals who represent the brightest minds in the medical device industry. The in-depth professional experience and tireless dedication of the ESTECH Team has allowed the company to achieve rapid and sustained success in this highly competitive environment. ESTECH is proud of each employee from every department and thanks them for their contribution and support.

Specific Diagnostics, LLC

Venture Round in 2019
Specific Diagnostics, LLC develops solutions for the detection, identification, and antibiotic susceptibility testing. It offers Specific Reveal system that provides antibiotic susceptibility results that allows clinics to deploy specific solutions. Specific Diagnostics, LLC was founded in 2011 and is headquartered in West Palm Beach, Florida.

Akoya Biosciences, Inc.

Series D in 2019
Akoya Biosciences is developing a novel high-parameter tissue analysis platform, at an order of magnitude beyond what is currently possible. Their CODEX (TM) (CO-Detection by indEXing) system enables deep proteomic profiling all on your existing microscope​. If you are a scientist or software engineer interested in revolutionizing the science of imaging, then Akoya is the place for you.

TECHNOMED

Merger/Acquisition in 2016
Technomed Engineering B.V., trading as Technomed Europe, engages in the development, production, and marketing of neurodiagnostic accessories for the neurophysiology market in Europe and internationally. The company’s products include reusable concentric, single fiber, monopolar needle, bar, bipolar felt pad, small stimulating, digital ring, surface, detachable stimulating and recording, grounding plate and wrap around, disposable and reusable subdermal needle, twisted disposable subdermal needle, disposable subdermal hooked needle, disposable and reusable cup, ear clip, and nasopharyngeal electrodes. Its products also comprise disposable adhesive surface, as well as concentric, monopolar, and hypodermic needle electrodes; reusable cables, sharpening kits for reusable needle electrodes, replacement felt pads, straps, alligator and grounding alligator clips, and electrode positioning systems; and collodions, preps, and pastes. The company’s disposable and reusable needle and surface electrodes are used to perform clinical/neurophysiologic examinations, such as muscle and brain activity registration, inoperative monitoring, nerve conduction studies, and evoked potentials. In addition, Technomed Engineering offers temperature probes, and medical diagnostic accessories of other manufacturers, such as ECG cables and lead wires. It sells its products through a distributor network in Belgium, Bulgaria, Croatia, the Czech Republic, Estonia, Finland, France, Germany, Greece, Italy, the Republic of Korea, Lithuania, Norway, Portugal, Sweden, Serbia, Spain, the Netherlands, Turkey, and the United Kingdom, as well as original equipment manufacturers. The company was founded in 1994 and is based in Beek, the Netherlands.

Carterra, Inc.

Private Placement in 2019
Carterra provides biotechnology solutions that develop and commercialize novel micro-array deposition technologies. The company provides users with instruments and services, which enable multiplexing on planar array surfaces. It also offers Continuous Flow Microspotter (CFM), which includes an array printing instrument and a microfluidic print head. Its products include spot CFM printhead, which uses a network of microchannels to deposit samples at one time in a block; and CFM instrument, which uses built-in sensors and pumps to control the flow within the CFM print head. It was founded in 2005 and headquartered in Salt Lake City, Utah.

Dynex Technologies, Inc.

Merger/Acquisition in 2017
Dynex Technologies, Inc. designs, engineers, manufactures, and distributes ELISA microplate workstations, laboratory instruments, and associated consumables and accessories. The company also offers technical support services. It provides its products through distributors in the United States, Canada, Mexico and South America, Asia, Europe, the Middle East and Africa, and internationally, as well as online. Dynex Technologies, Inc. was formerly known as Dynatech Laboratories, Inc. and changed its name to Dynex Technologies, Inc. in 1996. The company was founded in 1952 and is based in Chantilly, Virginia. Dynex Technologies, Inc. is a former subsidiary of Magellan Diagnostics, Inc.

BioVentrix, Inc.

Debt Financing in 2009
BioVentrix is a medical device company engaged in the improvement of treatments available for congestive heart failure. It is a biotechnology company that improves and expands the treatments available for congestive heart failure (CHF) caused by ischemic cardiomyopathy, through the development of less invasive and catheter-based approaches. The company was founded in 2003 and is headquartered in San Ramon, California, United States.

LDR Holding

Series C in 2007
LDR Holding Corporation develops and markets implantable spine systems and instrumentation for patients and the surgeon community in the United States and internationally. Its spinal surgery solutions include cervical and lumbar artificial disc systems, pedicle screw systems, implant systems, cervical cages, synthetic bone substitutes, and ALIF and TLIF devices, as well as VerteBRIDGE product, a direct lateral and oblique lumbar system for surgical applications. The company offers its products through partnerships with surgeons and distributors in Australia, Argentina, Austria, Belgium, Denmark, Greece, the Netherlands, Italy, Japan, Korea, Mexico, Malaysia, Peru, Portugal, South Africa, Spain, China, Switzerland, Taiwan, Thailand, Turkey, and the United Kingdom. LDR Holding Corporation was formerly known as LDR Spine USA, Inc. and changed its name after acquiring LDR Médical. The company was founded in 2004 and is based in Austin, Texas with additional offices in Troyes, France; Beijing, China; Sao Paolo, Brazil; and Munich, Germany.

Estech

Series D in 2010
ESTECH is a privately held medical device manufacturing and distribution company located in San Ramon, California. The company was founded by Arthur and Raymond Bertolero in 1996 with an emphasis on least invasive products for cardiac surgery. ESTECH has worldwide distribution and has consistently attracted goal oriented professionals who represent the brightest minds in the medical device industry. The in-depth professional experience and tireless dedication of the ESTECH Team has allowed the company to achieve rapid and sustained success in this highly competitive environment. ESTECH is proud of each employee from every department and thanks them for their contribution and support.

PneumRx

Venture Round in 2011
PneumRx, Inc., a start-up medical device company, develops minimally invasive treatments for emphysema patients. The company develops RePneu Lung Volume Reduction Coil, an investigational device for treating emphysema patients. PneumRx, Inc. was founded in 2004 and is based in Mountain View, California.

Nimble Therapeutics, Inc.

Private Placement in 2019
Nimble Therapeutics, Inc. operates as a biotechnology company. The company was incorporated in 2019 and is based in Madison, Wisconsin.

RareCyte

Venture Round in 2012
RareCyte is a life science research and diagnostic development company focused on characterizing and isolating rare cells in the blood. RareCyte is dedicated to bringing its innovative technology to the Life Sciences research, drug development, and diagnostic markets providing new tools to answer difficult questions related to cancer and cardiovascular disease. RareCyte's ground-breaking AccuCyte system is an open platform for the unbiased discovery and isolation of circulating tumor cells (CTCs) and circulating endothelial cells (CECs) from whole blood.

Confirma

Series C in 2008
Confirma is the only company that develops and markets an MRI-CAD system, CADstream, revolutionizing MRI study analysis and reporting through automated and standardized processing. CADstream automates the analysis and interventional guidance of MRI studies, providing higher quality imaging studies, lower costs for radiology practices and improved communication tools for physicians and patients. CADstream can be integrated into any workflow scenario and is compatible with all MRI scanners and PACS.

RareCyte

Venture Round in 2017
RareCyte is a life science research and diagnostic development company focused on characterizing and isolating rare cells in the blood. RareCyte is dedicated to bringing its innovative technology to the Life Sciences research, drug development, and diagnostic markets providing new tools to answer difficult questions related to cancer and cardiovascular disease. RareCyte's ground-breaking AccuCyte system is an open platform for the unbiased discovery and isolation of circulating tumor cells (CTCs) and circulating endothelial cells (CECs) from whole blood.