THE CATALYTIC IMPACT FOUNDATION (CIF)

The Catalytic Impact Foundation accelerates breakthroughs — championing extraordinary innovations, catalytic ideas, and, most importantly, visionary leaders. The Foundation aims to solve complex problems and accelerate innovations, alleviate human suffering, address inequities, and improve the quality of human life through disruptive and scalable projects in the life sciences, education, inclusive entrepreneurship and global sustainability. The Foundation is a registered 501(c)(3) charitable organization incorporated in New York State.

Rachel Butler

President

5 past transactions

Massive Bio

Series A in 2022
Massive Bio, Inc. is a New York-based company that offers testing and treatment advisory services tailored to cancer patients and oncologists. Founded in 2014, the company employs an artificial intelligence-powered platform to connect patients with clinical trials and optimize cancer care. Through its Personalized Oncology Advisor, Massive Bio integrates cancer genomics and targeted therapies into clinical decision-making, providing both diagnostic and treatment options, including access to clinical trials. The company operates two main platforms: a business-to-consumer (B2C) platform that delivers on-demand products and services for patients and their oncologists, and a business-to-business (B2B) platform designed for hospitals and insurance companies. Additionally, Massive Bio addresses patient enrollment challenges in clinical trials by utilizing advanced technology and real-world data to streamline processes, ensuring patients receive effective treatment while minimizing financial burdens. The company serves a diverse clientele that includes patients, oncologists, hospitals, and payers.

X-Therma

Series A in 2021
X-Therma is a biotechnology company focused on developing a unique biopreservation platform aimed at enhancing regenerative medicine. By employing convergent biomimetic nanotechnology, X-Therma addresses significant challenges in the storage of biological products. This innovative approach aims to optimize critical biomanufacturing processes, ensure safer transport, and facilitate long-term biobanking for various applications, including advanced cell therapies, in vitro fertilization (IVF), and organ transplants. The company's proprietary technology enables the cold chain preservation of living vaccines, cell and gene therapies, engineered tissues, and organs, thereby supporting healthcare professionals in delivering these vital treatments to patients more efficiently. Through its work, X-Therma seeks to unlock the full potential of regenerative medicines.

Cellevolve

Seed Round in 2021
Cellevolve Bio is a development and commercialization company specializing in cell therapies aimed at neglected diseases. The company collaborates with innovators to transition early-stage clinical therapies into commercially available treatments, particularly for pediatric and rare diseases. By advancing these therapies into clinical development, Cellevolve aims to significantly enhance patient outcomes and provide expertise in cell therapy and clinical care.

Medikabazaar

Series C in 2021
medikabazaar is a India’s pioneering and largest B2B online marketplace helping healthcare and other medical establishments in the procurement of medical supplies. We disrupted the medical supply market and leveled the playing field by launching a large-scale digital platform in 2015. With a catalog of more than 100,000 products, Medikabazaar is a single contact for purchase of medical supplies. Medikabazaar’s online platform cuts across geographical distances and enables the medical institutions in tier 2, 3 cities and remote locations in India to get quality medical supplies at competitive prices with the doorstep delivery. With its vast distribution setup, Medikabazaar aims to make last mile delivery of medical supplies available to every pin-code across India. We are presently serving 15,000+ Medical Centers; 80,000+ independent doctors and clinics across India for their regular medical supplies. We started from a one-room office in Mumbai, now we have 6 state-of-the-art regional offices and fulfillment centers spread across India. Our recent achievement includes National Icon Award 2018 for being India’s largest marketplace of medical equipment & devices.

Lyndra Therapeutics

Series C in 2021
Lyndra Therapeutics, Inc. specializes in the development of ultra-long-acting oral medications that provide sustained drug release over extended periods, ranging from a week to a month. By focusing on orally administered dosage forms that temporarily reside in the stomach, the company aims to transform the way medicines are taken, reducing the need for daily pills. Its portfolio includes therapies targeting a variety of health conditions, such as Alzheimer's disease, cardiovascular and metabolic disorders, psychiatric and opioid use disorders, immunology, HIV, malaria vector control, and oral contraceptives. Founded in 2015 and headquartered in Watertown, Massachusetts, Lyndra Therapeutics is committed to enhancing medication adherence and improving health outcomes while also aiming to lower healthcare costs through innovative delivery methods.
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