Duke Capital Partners

Duke Capital Partners is a venture capital investment firm based in Durham, North Carolina, established in 2015. The firm focuses on investing in the consumer and life science sectors, aiming to support innovative companies in these fields. In addition to its investment activities, Duke Capital Partners is committed to educating the next generation of investment professionals and startup founders through its associate program. This initiative not only fosters talent but also enhances the overall ecosystem for emerging businesses.

Kurt Schmidt

Managing Director

11 past transactions

Octane

Seed Round in 2025
Octane is a developer-focused platform that leverages cutting-edge artificial intelligence to battle-test smart contracts.

VQ Biomedical

Seed Round in 2025
VQ Biomedical is a medical technology company developing a minimally invasive catheter to deliver supplemental oxygen directly into the bloodstream of hospitalized patients suffering from respiratory failure. This innovative device aims to provide a safer, more efficient, and less invasive solution for respiratory support, as it does not require the patient's blood to be pumped outside the body.

Acre

Seed Round in 2024
Acre is a real estate technology platform developed to improve the homeownership experience. Acre provides assistance at the time of purchasing a house by allowing to invest the amount of the home that is convenient, allowing customers to buy a new home at a lower monthly payment and lower risk than a traditional mortgage.

Liquid AI

Series A in 2024
Liquid AI is a technology company that develops artificial intelligence solutions for various applications. It focuses on creating tools for data analysis and decision-making processes. Liquid AI serves industries such as finance, healthcare, and logistics.

dannce.ai

Pre Seed Round in 2024
Dannce.ai specializes in developing markerless 3D motion capture technology, DANNCE, which employs deep learning to quantify behavior and detect neurological diseases. By analyzing fine 3D patient movement, Dannce.ai creates distinct 'behavioral fingerprints' that correspond to specific disease states and drug effects, accelerating drug development and enhancing diagnostic accessibility.

Pryon

Series B in 2023
Pryon Inc. is an artificial intelligence company based in Raleigh, North Carolina, founded in 2017. It specializes in enterprise knowledge management through its augmented intelligence platform, which effectively combines human capabilities with machine intelligence. The platform enhances productivity by transforming unstructured data into actionable insights, utilizing advanced techniques such as natural language processing and automated machine learning. By providing context-aware access to knowledge and streamlining workflows, Pryon enables organizations to reduce complexity and operational costs while maximizing the value of their information assets. The company was established by Igor Jablokov, who previously developed AI assistants that contributed to the foundation of Alexa.

SiPhox Health

Series A in 2023
SiPhox Health, based in Cambridge, Massachusetts, specializes in designing and manufacturing innovative diagnostic solutions. The company develops next-generation diagnostics infrastructure, including at-home test kits and central lab systems. Their flagship product is a disposable biosensor cartridge that assesses 17 blood biomarkers, providing insights into inflammation, hormonal health, metabolic fitness, and cardiovascular health. SiPhox Health's platform merges biochemistry, photonic chip technology, integrated photonics, electronics, and microfluidics to enable sensitive readouts of immunoassays and nucleic acid tests, facilitating point-of-need and at-home diagnostics.

Levitate

Series C in 2023
Levitate is a developer of a customer relationship management platform that focuses on supporting relationship-based businesses. The company aims to foster a more entrepreneurial and creative environment by providing software solutions tailored for small businesses and entrepreneurial teams within larger organizations. Levitate's platform leverages artificial intelligence to assist small and medium-sized enterprises in managing their professional relationships effectively. It offers features such as templates, messaging functions, and relationship analytics, enabling users to maintain communication with clients, prospects, and referral sources efficiently.

DIA

Grant in 2023
Dia has invented an electrochemical sensor that can measure a wide variety of chemical biomarkers non-invasively in saliva or sweat. The data is sent via Bluetooth to an app on the user’s smartphone and analyzed in real-time. From the app, it can be securely sent to a third party. To date, we have measured hormones, electrolytes, neurotransmitters and metabolites. At DIA, we let the biology dictate which analyte we put on which platform – our wearable arm sleeve for sweat or our table-top device for saliva – because some biomarkers, such as cortisol fluctuate throughout the day and need to be monitored through a wearable sensor, while others, such as creatinine are more suitable to a daily saliva test.

Levitate

Venture Round in 2022
Levitate is a developer of a customer relationship management platform that focuses on supporting relationship-based businesses. The company aims to foster a more entrepreneurial and creative environment by providing software solutions tailored for small businesses and entrepreneurial teams within larger organizations. Levitate's platform leverages artificial intelligence to assist small and medium-sized enterprises in managing their professional relationships effectively. It offers features such as templates, messaging functions, and relationship analytics, enabling users to maintain communication with clients, prospects, and referral sources efficiently.

Otter.ai

Venture Round in 2020
Otter.ai, Inc. is a technology company specializing in artificial intelligence-driven applications designed for capturing and managing voice conversations. Founded in 2016 and headquartered in Los Altos, California, Otter.ai offers a collaborative note-taking platform that allows users to generate, store, and share notes from meetings, interviews, and lectures in real-time. Its flagship product, Otter, utilizes advanced speech recognition technology to provide features such as speaker separation, speaker identification, and keyword extraction, making it easier for individuals, teams, and educational institutions to access and organize important information. The application is widely used by business professionals, journalists, and students to enhance productivity and collaboration by transforming voice conversations into searchable and actionable notes.
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