Sprig Equity

Conformal Medical, Inc., established in 2016 and based in Nashua, New Hampshire, specializes in developing medical devices aimed at preventing stroke in patients with atrial fibrillation (AFib). The company's primary product is the CLAAS Technology, a solution designed to seal the left atrial appendage (LAA) in AFib patients. This technology forms part of their conformal left atrial appendage closure (LAAC) system.

CytoVale is a medical technology company based in San Francisco that develops biomarkers derived from the mechanical properties of single cells. The company uses microfluidics to route and probe cells, enabling the measurement of multiple biophysical indicators at once. Its technology aims to advance early detection of immune-mediated diseases and sepsis through the analysis of cell mechanics and machine learning. By translating biophysical signals into diagnostic information, CytoVale seeks to improve diagnostic accuracy, support timely treatment decisions, and reduce healthcare costs.

Pi-Cardia is a medical device start-up focused on developing an innovative low-profile catheter for the treatment of aortic stenosis. The company's proprietary technology utilizes a trans-femoral catheter that incorporates nitinol elements to deliver mechanical impact, creating fractures in calcified heart valves without damaging the surrounding soft tissue. This rapid treatment approach aims to enhance the effective orifice area of the valve, providing a cost-effective and durable solution that eliminates the need for valve replacement. By addressing the challenges associated with aortic stenosis, Pi-Cardia seeks to improve patient outcomes and streamline the treatment process for healthcare providers.