Gilde Healthcare

Gilde Healthcare Partners B.V. is a private equity and venture capital firm based in Utrecht, Netherlands, with additional offices in Cambridge, Massachusetts, and Frankfurt am Main, Germany. Established in 2000, the firm specializes in investing in the healthcare sector, focusing on healthcare technology, medtech, diagnostics, digital health, therapeutics, and healthcare services. Gilde Healthcare targets lower mid-market companies and seeks to lead investments, typically investing between €1 million and €35 million in firms with enterprise values up to €150 million. The firm emphasizes sectors such as biopharma, medical devices, clinical decision support, and various healthcare services, including primary and specialized care. Gilde Healthcare aims to take both majority and minority stakes in its portfolio companies and actively participates in their management by securing board positions. The firm primarily invests in the United States and Europe, particularly in the Benelux region.

Rene Bernards Ph.D

Operations Partner

Dirkjan Beugelsdijk

Finance Director

Josephine Bogaerts

Senior Associate, Private Equity

Arthur Franken

Partner

van Gorp, Jasper

Managing Partner

Edwin de Graaf

Managing Partner

Hofbauer, Karl G.

Operational Partner

Komen, Job

Partner

Stefan Luzi

Partner

Pieter van der Meer

Managing Partner and Founder

Mika Nishimura

Operational Partner

Marc Olivier Perret

Managing Partner

Pinedo, Herbert Michael

Operational Partner

Tom Klein Robbenhaar

Partner, Investment Manager

Robert Stein

Partner, Private Equity

Matthew Vessa

Vice President

Geoffrey Waters

Operational Partner

West, Paul

Operational Partner

Past deals in Denmark

KLIFO

Acquisition in 2021
KLIFO is a consulting firm specializing in drug development, partnering with biotechnology and pharmaceutical companies to enhance their drug development projects. The company provides comprehensive solutions across various aspects of clinical research, including clinical operations, clinical trial supply, regulatory affairs, and pharmacovigilance. KLIFO also focuses on the development of pharmaceutical and biotech products as well as medical devices. By leveraging its multidisciplinary expertise, KLIFO aims to help its partners maximize opportunities, mitigate risks, and drive innovation, thereby facilitating efficient project advancement in the life sciences sector.

ADCendo

Series A in 2021
ADCendo ApS is a biotechnology company focused on developing innovative anti-cancer drugs through the use of antibody-drug conjugates (ADCs). The company targets novel receptors that are overexpressed in various cancer types, addressing significant unmet medical needs in the field of oncology. Its ADCs aim to provide targeted therapy for patients suffering from aggressive cancers such as soft-tissue sarcoma, osteosarcoma, glioblastoma multiforme, and triple-negative breast cancer, as well as other carcinomas including those of the breast, colon, pancreas, prostate, ovary, and kidney. Through its research and development efforts, ADCendo strives to create effective treatment options for patients facing challenging cancer diagnoses.

Draupnir Bio

Seed Round in 2019
Draupnir Bio intends to develop a new type of cholesterol-lowering medicine that prevents blood clots in the heart more effectively than the current medicine. The company is developing a platform for exploring the glycome to develop novel therapeutics, based on array technology, protein chemistry, and advanced carbohydrate chemistry. The company is able to synthesize, screen, and select highly potent and specific heparan sulfate glycomimetic drug candidates in cardiovascular, inflammatory, and infectious diseases.

Santaris Pharma

Venture Round in 2012
Santaris Pharma A/S is a privately held clinical-stage biopharmaceutical company focused on the discovery and development of RNA-targeted therapies. The LNA Drug Platform and Drug Discovery Engine developed by Santaris Pharma A/S combine the company’s proprietary LNA chemistry with its highly specialized and targeted drug development capabilities to rapidly deliver potent single-stranded LNA-based drug candidates across a multitude of disease states. The company’s research and development activities focus on infectious diseases and cardiometabolic disorders, while partnerships with major pharmaceutical companies include a range of therapeutic areas including cancer, cardiovascular disease, infectious and inflammatory diseases, and rare genetic disorders. The company has strategic partnerships with miRagen Therapeutics, Shire PLC, Pfizer, GlaxoSmithKline, and Enzon Pharmaceuticals. As part of its broad patent estate, the company holds exclusive worldwide rights to manufacture, have manufactured and sell products that contain LNA as an active ingredient for studies performed with a view to obtaining marketing approval. Santaris Pharma A/S, founded in 2003, is headquartered in Denmark with operations in the United States.

Santaris Pharma

Series C in 2007
Santaris Pharma A/S is a privately held clinical-stage biopharmaceutical company focused on the discovery and development of RNA-targeted therapies. The LNA Drug Platform and Drug Discovery Engine developed by Santaris Pharma A/S combine the company’s proprietary LNA chemistry with its highly specialized and targeted drug development capabilities to rapidly deliver potent single-stranded LNA-based drug candidates across a multitude of disease states. The company’s research and development activities focus on infectious diseases and cardiometabolic disorders, while partnerships with major pharmaceutical companies include a range of therapeutic areas including cancer, cardiovascular disease, infectious and inflammatory diseases, and rare genetic disorders. The company has strategic partnerships with miRagen Therapeutics, Shire PLC, Pfizer, GlaxoSmithKline, and Enzon Pharmaceuticals. As part of its broad patent estate, the company holds exclusive worldwide rights to manufacture, have manufactured and sell products that contain LNA as an active ingredient for studies performed with a view to obtaining marketing approval. Santaris Pharma A/S, founded in 2003, is headquartered in Denmark with operations in the United States.

Symphogen

Venture Round in 2007
Symphogen specializes in the development of recombinant polyclonal antibodies (rpAb), a novel class of biopharmaceuticals aimed at treating and preventing serious human diseases, including infectious diseases and cancer. The company has created compositions of recombinant polyclonal antibodies for specific medical applications, such as the treatment of idiopathic thrombocytopenic purpura and the prevention of hemolytic disease in newborns. These innovations help mitigate adverse reactions from smallpox vaccinations and facilitate quicker treatment initiation for cancer patients, ultimately improving the chances of successful outcomes.

Symphogen

Series D in 2006
Symphogen specializes in the development of recombinant polyclonal antibodies (rpAb), a novel class of biopharmaceuticals aimed at treating and preventing serious human diseases, including infectious diseases and cancer. The company has created compositions of recombinant polyclonal antibodies for specific medical applications, such as the treatment of idiopathic thrombocytopenic purpura and the prevention of hemolytic disease in newborns. These innovations help mitigate adverse reactions from smallpox vaccinations and facilitate quicker treatment initiation for cancer patients, ultimately improving the chances of successful outcomes.
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