Indaco Venture Partners

Indaco Venture Partners is a Milan-based venture capital firm that backs growth-stage companies in electronics, robotics, medtech, biotech, digital, and new materials. The firm emphasizes Italian enterprises while investing across Europe, the United States, Canada, and Israel, seeking proprietary technologies and innovations as competitive advantages.

Antonella Beltrame

Co-Founder, Investment Director and Board Member

Cosimo Calcagno

Senior Investment Manager

Lukas Hill

Investment Manager

Adriana Piccitto

Investment Manager

Carlo Sanfilippo

Senior Investment Manager

Davide Turco

Co-Founder and Managing Director

Simone Zanolo

Venture Partner

41 past transactions

Iama Therapeutics

Venture Round in 2025
Iama Therapeutics specializes in neuroscience drug discovery, aiming to develop innovative medicines for children with brain disorders. Their mission is to improve the lives of these children and provide support to their families.

CamGraPhIC

Series A in 2025
CamGraPhIC is an integrated photonics platform that focuses on addressing the growing demand for data traffic through its advanced electro-optical engines. The company specializes in graphene photonics technology, which enhances optical telecommunications, particularly in 5G and data center applications. Its solutions are characterized by high data rates, low costs, and low power consumption, making them ideal for next-generation optical transceivers. CamGraPhIC's technology is compatible with various photonic materials, including silicon and silicon nitride, and can be synthesized and integrated using scalable wafer-level processes. This capability enables clients to efficiently utilize the bandwidth necessary for emerging digital applications, such as cloud services and the Internet of Things.

Valo Therapeutics

Venture Round in 2025
Valo Therapeutics is an immunotherapy company focused on developing antigen-coated oncolytic viruses as therapeutic vaccines for cancer treatment. Founded in 2016 and based in Oxford, United Kingdom, with an additional office in Helsinki, Finland, the company utilizes its innovative Valo Tx platform, which includes PeptiCRAd, an engineered human oncolytic adenovirus. This platform is designed to induce systemic anti-tumor T cell responses by transforming oncolytic adenoviruses into targeted, tissue-specific cancer vaccines without requiring the production of multiple genetically modified viruses. Valo Therapeutics is also advancing other neoantigen strategies, including PeptiENV, in collaboration with Professor Vincenzo Cerullo from the University of Helsinki, to enhance therapeutic responses against various cancer types.

Newronika

Series B in 2025
Newronika develops innovative neuro-modulation devices aimed at restoring brain and body functions. The company translates its deep expertise in biosignal decoding into clinical practice, enabling patients to receive targeted stimulation for improved daily activities and enhanced quality of life.

Easy Rain

Venture Round in 2025
Easy Rain i.S.p.A. is an Italian company founded in 2013, based in Milan, that specializes in enhancing vehicle safety through innovative technology. It has developed a patented active safety system that addresses the hydroplaning phenomenon, which occurs when vehicles lose traction on wet roads due to a layer of water. This issue contributes to millions of accidents annually and poses significant challenges for autonomous driving technologies. Easy Rain’s system prevents excessive water from contacting the tires, thereby improving traction and overall vehicle performance in wet conditions. The company holds extensive patent coverage for its technology and offers solutions that can integrate with remote detection and vision systems to further enhance safety and efficiency for both conventional and electric vehicles.

TES Pharma

Series A in 2024
TES Pharma is a research-based biopharmaceutical company focusses on delivering first in class preclinical candidates that unlock the potential of novel therapeutic targets and mechanisms.

D-Orbit

Series C in 2024
Founded in 2011, D-Orbit is an Italian New Space company specializing in satellite life cycle management. It offers solutions for satellite design, launch, commissioning, and decommissioning, with a focus on safe disposal of artificial satellites at the end of their life to mitigate space debris.

Genespire

Series B in 2024
Genespire is a biotechnology company dedicated to developing innovative gene therapies for patients suffering from genetic diseases, with a particular emphasis on primary immunodeficiencies and inherited metabolic disorders. The company specializes in creating therapies that utilize integration-defective lentiviral vectors combined with gene editing techniques. This approach allows for highly effective and adaptable targeted insertion of therapeutic genes into blood cells, providing patients with a range of tailored therapeutic options suited to their specific conditions. By focusing on transformative solutions, Genespire aims to significantly improve the lives of individuals affected by severe genetic disorders.

WISE

Series D in 2024
WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Freya Biosciences

Series A in 2023
Freya Biosciences is a clinical-stage company specializing in women's health. It develops microbial immunotherapies, focusing on unmet needs across various indications.

Hoba Therapeutics

Series A in 2023
Hoba Therapeutics is focused on developing innovative biopharmaceuticals aimed at treating neuropathic pain and central nervous system disorders. The company is advancing a novel therapeutic protein designed to target specific cells, providing medical practitioners with effective and safe options for managing chronic pain and hearing loss. Through its research and development efforts, Hoba Therapeutics seeks to deliver disease-modifying treatments that enhance the quality of life for patients suffering from neuropathic pain.

Nouscom

Series C in 2023
Nouscom is a biotechnology company focused on developing an immunotherapy platform that creates engineered viral vector vaccines for cancer treatment. The company's innovative platform leverages a portfolio of modified viral vectors, specifically designed for the efficient expression of long strings of tumor neoantigens. This approach is complemented by a toolkit that facilitates the induction of robust antitumor T-cell responses, effectively enhancing cancer-specific cellular immunity in patients. Through its research and development efforts, Nouscom aims to improve cancer treatment outcomes by harnessing the body's immune system to target and combat cancer cells.

D-Orbit

Series C in 2023
Founded in 2011, D-Orbit is an Italian New Space company specializing in satellite life cycle management. It offers solutions for satellite design, launch, commissioning, and decommissioning, with a focus on safe disposal of artificial satellites at the end of their life to mitigate space debris.

Easy Rain

Venture Round in 2023
Easy Rain i.S.p.A. is an Italian company founded in 2013, based in Milan, that specializes in enhancing vehicle safety through innovative technology. It has developed a patented active safety system that addresses the hydroplaning phenomenon, which occurs when vehicles lose traction on wet roads due to a layer of water. This issue contributes to millions of accidents annually and poses significant challenges for autonomous driving technologies. Easy Rain’s system prevents excessive water from contacting the tires, thereby improving traction and overall vehicle performance in wet conditions. The company holds extensive patent coverage for its technology and offers solutions that can integrate with remote detection and vision systems to further enhance safety and efficiency for both conventional and electric vehicles.

Alia Therapeutics

Seed Round in 2023
Alia Therapeutics develops gene-editing medicines to treat rare genetic diseases. It focuses on next-generation CRISPR technologies that expand targetable genomic sites and improve modification precision, enabling therapies with greater specificity and safety that address genetic disorders at their roots.

Sibylla Biotech

Series A in 2022
Sibylla Biotech S.R.L. is an Italian biotechnology company focused on the research and development of innovative solutions for drug design. The company specializes in producing small molecule folding interfering degraders (FIDs) that target various therapeutic areas. Sibylla Biotech employs advanced patent-based software that utilizes algorithms and drug design protocols to enhance drug discovery processes. By implementing original reaction path sampling and data reduction techniques, the software aims to streamline the development of treatments for incurable diseases. In addition to its product development, Sibylla Biotech offers consultancy services in biotechnology and drug development, supporting medical practitioners in rationalizing their research efforts. The company is headquartered in Italy.

InnovHeart

Series C in 2022
InnovHeart is a medical device company that develops transcatheter mitral valve replacement systems to treat mitral valve disease. Its implant technology is designed to replace diseased mitral valves using a transcatheter approach, enabling hospitals to perform safer and more accessible valve replacement procedures. The company aims to provide a safe, effective, and easy-to-use solution for patients suffering from mitral valve dysfunction.

CYSEC

Seed Round in 2022
CYSEC specializes in next-generation Confidential Computing solutions, securing data at rest, in motion, and in use. Their flagship product, ARCA, is a popular choice in the market.

CellPly

Venture Round in 2021
CellPly is a life-science company specializing in advanced analytical tools for deep characterization of cancer immunotherapies, cell therapies, and biotherapeutics. It accelerates R&D and automates quality control processes using proprietary microfluidic technologies, Co-Culture Array technology, highly-automated instruments, and AI-powered image analytics. By defining immune system function at the single-cell level and combining functional data with multiplex data, CellPly enables personalized cancer treatment by supporting the development of novel immunotherapies and monitoring clinical responses to treatments.

Cortilia

Series C in 2021
Cortilia is a grocery delivery company based in Milan, Italy, founded in 2011. It operates an online agricultural marketplace that connects consumers directly with local farmers, providing access to fresh, artisanal, and seasonal products. By aggregating farmers in virtual markets, Cortilia enhances the local economy while minimizing waste. The company ensures that products are packed and delivered to customers' doors within a few hours, prioritizing quality and freshness. This sustainable approach allows consumers to easily access farm and dairy products, fostering a more direct relationship between producers and consumers.

WISE

Series C in 2020
WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

InnovHeart

Series B in 2020
InnovHeart is a medical device company that develops transcatheter mitral valve replacement systems to treat mitral valve disease. Its implant technology is designed to replace diseased mitral valves using a transcatheter approach, enabling hospitals to perform safer and more accessible valve replacement procedures. The company aims to provide a safe, effective, and easy-to-use solution for patients suffering from mitral valve dysfunction.

Enthera

Series A in 2020
Enthera is an Italian biotechnology startup established in October 2016 by BiovelocITA, Professor Paolo Fiorina, and Dr. Francesca D'Addio. The company specializes in developing biotherapeutics aimed at treating autoimmune disorders, with a focus on type 1 diabetes and inflammatory bowel disease. Enthera's pipeline targets key pathways involved in cell apoptosis in the gut, pancreas, and other organs to combat these intractable conditions effectively.

Expert.ai

Post in 2020
Expert.ai is an enterprise artificial intelligence company that specializes in natural language processing and understanding, offering a platform that blends symbolic human‑like comprehension with machine learning to transform language‑intensive processes into practical knowledge. Its Cogito Discover product provides analytics, extraction, and categorization across taxonomies, enabling automation of text from formats such as XML and RDF. The company supports flexible deployment options, including on‑premise, private cloud, and public cloud, and serves industries that span insurance, banking and finance, publishing and media, defense and intelligence, and life sciences and pharma; it also delivers biomedical research solutions such as Clinical Research Navigator to aid therapy research for infectious diseases.

D-Orbit

Series C in 2019
Founded in 2011, D-Orbit is an Italian New Space company specializing in satellite life cycle management. It offers solutions for satellite design, launch, commissioning, and decommissioning, with a focus on safe disposal of artificial satellites at the end of their life to mitigate space debris.

D-Orbit

Series B in 2019
Founded in 2011, D-Orbit is an Italian New Space company specializing in satellite life cycle management. It offers solutions for satellite design, launch, commissioning, and decommissioning, with a focus on safe disposal of artificial satellites at the end of their life to mitigate space debris.

Intrepida Bio

Venture Round in 2019
Intrepida Bio, Inc. is a biotechnology company focused on developing innovative cancer therapies that enhance the body’s innate immune response. Founded in 2016 and headquartered in San Diego, California, the company specializes in creating medicines that modulate the innate immune system to combat cancer and other diseases. Intrepida Bio is particularly engaged in the development of monoclonal antibodies aimed at novel targets such as BAG3 and its receptor IFITM-2, which are involved in establishing a tumor-friendly environment. Through its research efforts, Intrepida Bio aims to provide patients with effective treatment options to fight cancer.

Newronika

Series A in 2019
Newronika develops innovative neuro-modulation devices aimed at restoring brain and body functions. The company translates its deep expertise in biosignal decoding into clinical practice, enabling patients to receive targeted stimulation for improved daily activities and enhanced quality of life.

Cortilia

Series B in 2019
Cortilia is a grocery delivery company based in Milan, Italy, founded in 2011. It operates an online agricultural marketplace that connects consumers directly with local farmers, providing access to fresh, artisanal, and seasonal products. By aggregating farmers in virtual markets, Cortilia enhances the local economy while minimizing waste. The company ensures that products are packed and delivered to customers' doors within a few hours, prioritizing quality and freshness. This sustainable approach allows consumers to easily access farm and dairy products, fostering a more direct relationship between producers and consumers.

BiovelocITA

Venture Round in 2019
BiovelocITA fosters the development of pioneering biotechnology companies by bringing together top scientists, entrepreneurs, and investors. Co-founded by Sofinnova Partners, a leading player in Italy's biotech market for over fifteen years, BiovelocITA aims to accelerate growth in this sector.

UltraSoC

Series E in 2019
UltraSoC Technologies Ltd., established in 2005 and headquartered in Cambridge, UK, specializes in semiconductor intellectual property (IP) for system monitoring, analysis, and optimization. The company's core offering is an independent, non-intrusive system-level architecture that enables real-time, wire-speed monitoring of System-on-Chip (SoC) internal behavior. This IP accelerates and de-risks development by providing engineers with insights into complex interactions between on-chip sub-systems, buses, and software. UltraSoC's toolkit comprises configurable modules and software for IP configuration, debug, and analytics, serving applications in SoC debug, analytics and optimization, in-field monitoring, and security. Since June 2020, UltraSoC operates as a subsidiary of Siemens AG.

MainStreaming

Series B in 2019
MainStreaming specializes in broadcast-quality live video delivery via edge networks. It serves major live streaming operations, optimizing viewing experiences and maximizing investment returns.

Sweetguest

Series B in 2019
Sweetguest s.r.l., founded in 2016 and based in Milan, Italy, specializes in providing comprehensive management services for short-term rental properties. The company has developed a mobile application that streamlines the reservation process and offers a full range of services to both property owners and their guests. Sweetguest manages all aspects of short-term rentals, including reservations, check-ins, check-outs, laundry, and cleaning. By handling these tasks, Sweetguest enables property owners to maximize their earnings while saving time and effort, ensuring a high-quality experience for everyone involved.

Talent Garden

Series B in 2019
Talent Garden is a leading digital skills academy based in Europe, founded in Italy in 2011. It aims to empower individuals and organizations by providing the knowledge, resources, and spaces necessary for thriving within the innovation ecosystem. The company offers a variety of learning experiences, including online, offline, and hybrid courses, as well as corporate programs and events. Talent Garden operates a network of coworking campuses that fosters a vibrant community of over 45,000 professionals in the digital and tech sectors. Its mission focuses on closing the digital skills gap, having successfully trained more than 25,000 individuals in areas such as digital design, marketing, product management, and cybersecurity. By collaborating with major partners, Talent Garden delivers tailored corporate education programs to promote digital transformation. Its campuses, open 24 hours a day, are designed to facilitate collaboration and provide professionals with a supportive environment to thrive and innovate.

The Data Appeal Company

Series A in 2018
The Data Appeal Company, established in 2014, specializes in AI-driven data analysis and visualization. Headquartered in Florence, Italy, with offices across Europe, the company collects and interprets geographical data, online feedback, customer behaviors, and trends. Its core products, Travel Appeal and Data Appeal Studio, empower businesses to understand and enhance customer experiences through real-time insights, predictive analysis, and semantic understanding. The company's mission is to democratize data usage, making it accessible and understandable for informed decision-making.

Bendit

Convertible Note in 2018
Bendit is a medical company specializing in the development and manufacturing of innovative catheters that utilize a unique bending technology. This technology provides enhanced steering capabilities in both micro diameter and conventional catheter wires and tubes. The company focuses on creating microcatheter devices that enable precise navigation within the body, allowing healthcare professionals to access targeted sites with minimal tools and reduced risks. Bendit's products are designed to improve the success rates of medical procedures by offering peripheral and visceral microcatheters that can be shaped and directed as needed. The company is a joint venture formed by three experienced groups in production, quality and regulation, and medical development, bringing together expertise to advance catheter technology.

Easy Rain

Series A in 2017
Easy Rain i.S.p.A. is an Italian company founded in 2013, based in Milan, that specializes in enhancing vehicle safety through innovative technology. It has developed a patented active safety system that addresses the hydroplaning phenomenon, which occurs when vehicles lose traction on wet roads due to a layer of water. This issue contributes to millions of accidents annually and poses significant challenges for autonomous driving technologies. Easy Rain’s system prevents excessive water from contacting the tires, thereby improving traction and overall vehicle performance in wet conditions. The company holds extensive patent coverage for its technology and offers solutions that can integrate with remote detection and vision systems to further enhance safety and efficiency for both conventional and electric vehicles.

Bendit

Series A in 2017
Bendit is a medical company specializing in the development and manufacturing of innovative catheters that utilize a unique bending technology. This technology provides enhanced steering capabilities in both micro diameter and conventional catheter wires and tubes. The company focuses on creating microcatheter devices that enable precise navigation within the body, allowing healthcare professionals to access targeted sites with minimal tools and reduced risks. Bendit's products are designed to improve the success rates of medical procedures by offering peripheral and visceral microcatheters that can be shaped and directed as needed. The company is a joint venture formed by three experienced groups in production, quality and regulation, and medical development, bringing together expertise to advance catheter technology.

UltraSoC

Series D in 2017
UltraSoC Technologies Ltd., established in 2005 and headquartered in Cambridge, UK, specializes in semiconductor intellectual property (IP) for system monitoring, analysis, and optimization. The company's core offering is an independent, non-intrusive system-level architecture that enables real-time, wire-speed monitoring of System-on-Chip (SoC) internal behavior. This IP accelerates and de-risks development by providing engineers with insights into complex interactions between on-chip sub-systems, buses, and software. UltraSoC's toolkit comprises configurable modules and software for IP configuration, debug, and analytics, serving applications in SoC debug, analytics and optimization, in-field monitoring, and security. Since June 2020, UltraSoC operates as a subsidiary of Siemens AG.

Directa Plus

Venture Round in 2015
Directa Plus is a nanotechnology company that develops and manufactures graphene-based products for industrial and consumer markets. It focuses on creating manufacturing processes to produce high-quality engineered graphene materials, marketed under the G+ brand. Its products are used in elastomers, textiles, composite materials, water treatment, oil-spill response, golf balls, and footwear, and the company serves both textile and environmental sectors, among others, with international sales from its base in Lomazzo, Italy.

CellPly

Seed Round in 2014
CellPly is a life-science company specializing in advanced analytical tools for deep characterization of cancer immunotherapies, cell therapies, and biotherapeutics. It accelerates R&D and automates quality control processes using proprietary microfluidic technologies, Co-Culture Array technology, highly-automated instruments, and AI-powered image analytics. By defining immune system function at the single-cell level and combining functional data with multiplex data, CellPly enables personalized cancer treatment by supporting the development of novel immunotherapies and monitoring clinical responses to treatments.
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