IndieBio

Prellis Biologics, Inc. specializes in creating human tissues for drug development and the eventual production of human organs for transplantation. Founded in 2016 and based in San Francisco, California, the company employs advanced bioprinting technology to develop vascularized human tissues and organs, aiming to overcome the challenges associated with microvasculature. Its innovative products include TissueWorkshop, Organoids, Vascular Bundles, Tissue Chips, and Holograph X. Prellis Biologics also focuses on accurately replicating the human immune response through lymph node organoids, which can be utilized for various applications such as antibody discovery and immunogenicity assessment. By addressing critical issues in early-stage drug development and translational pharmacology, Prellis Biologics seeks to improve patient outcomes in healthcare.

AlkaLi Labs is a biotechnology research company based in San Francisco, California, established in 2023. The company focuses on developing biological solutions to harness domestic mineral resources. Currently operating in stealth mode, AlkaLi Labs aims to innovate in the field of biotechnology, leveraging biological processes to unlock valuable minerals.

Laguna Bio is a biotechnology company based in Berkeley, California, founded in 2022. The company focuses on drug discovery, specifically developing a platform that activates and expands the innate immune system to combat cancer. Laguna Bio specializes in enhancing a specific type of T cell that targets solid tumors, aiming to improve the efficacy of bispecific antibody drugs. By increasing the immune response against these tumors, the company seeks to provide innovative solutions that may help patients survive cancer more effectively.

Sóliome is a biotechnology company founded in 2021 and based in San Francisco, California. The company specializes in developing protein-based sunscreens designed to be safe for both the skin and the environment. These innovative products aim to reduce inflammation and skin damage caused by traditional sunscreens, which often contain harmful xenobiotic ingredients that can absorb into the skin and contribute to ecological harm. Sóliome's approach allows customers to protect their skin from harmful rays without the adverse effects associated with conventional sunscreen formulations.

Finless Foods Inc. is a biotechnology company based in Emeryville, California, that specializes in producing seafood products for human consumption using cellular-agriculture technologies. Founded in 2017, the company focuses on growing marine-animal cells to create alternatives to traditional fish and seafood, including bluefin tuna. By offering a variety of responsibly produced food options, Finless Foods aims to cater to diverse tastes and dietary needs while promoting sustainability and better ocean health. The company's innovative approach provides consumers with healthy and accessible seafood alternatives, enabling them to maintain a balanced diet without compromising on flavor or variety.

California Cultured is a food company based in Davis, California, that specializes in producing sustainable, lab-grown cocoa through advanced cellular agriculture techniques. Founded in 2020, the company aims to create cocoa that is less bitter and requires less sugar, enhancing the taste while promoting health benefits. By stimulating cocoa cells with common food ingredients, California Cultured ensures the growth of premium-quality cocoa without the ethical and environmental issues associated with traditional cocoa production, such as slavery and deforestation. This innovative approach allows customers to enjoy delicious cocoa products that are both sustainable and socially responsible.

Avisa Myko Inc. is a biotechnology company based in San Francisco, California, specializing in the production of natural, water-soluble melanin. The company has developed a patented technology that allows for the large-scale and cost-effective manufacturing of melanin, which is used across various industries, including cosmetics, biomedicine, and environmental applications. Avisa Myko's melanin offers protection against ionizing radiation and is integrated into products such as latex, fabrics, laminated plastics, and glass. Additionally, the company is working on formulating a sunscreen that utilizes melanin as a natural ultraviolet blocker, eliminating the need for traditional chemical or mineral UV filters. By focusing on sustainable solutions, Avisa Myko aims to enhance human health and environmental safety through its innovative melanin products.

ZymoChem, Inc. is a biotechnology company based in Emeryville, California, founded in 2013. It specializes in the development of eco-friendly chemicals and bioprocesses using engineered microbes to convert renewable feedstocks, such as sugars, into industrial chemicals. The company’s bio-manufacturing platform aims to produce bio-based materials while minimizing carbon emissions during production, thereby supporting a carbon-efficient economy. By establishing cost-effective bioprocesses and novel biosynthetic pathways, ZymoChem enables clients to reduce production costs and enhance their competitiveness in the market. Through its innovative approach, the company contributes to sustainable manufacturing practices and the advancement of a real-zero economy.

Chronus Health, Inc. is a company that specializes in developing a portable diagnostic platform aimed at delivering rapid point-of-care lab results, specifically for complete blood count and comprehensive metabolic panel tests. Founded in 2017 and based in Mountain View, California, the company's innovative system utilizes microfluidics and semiconductor technology, combined with data analytics, to provide healthcare providers with real-time test results. This capability allows for immediate diagnosis at the point of care, enhancing the efficiency of treatment and significantly improving patient outcomes. By enabling doctors to obtain lab results in minutes, Chronus Health facilitates timely decision-making in clinical settings.

Prellis Biologics, Inc. specializes in creating human tissues for drug development and the eventual production of human organs for transplantation. Founded in 2016 and based in San Francisco, California, the company employs advanced bioprinting technology to develop vascularized human tissues and organs, aiming to overcome the challenges associated with microvasculature. Its innovative products include TissueWorkshop, Organoids, Vascular Bundles, Tissue Chips, and Holograph X. Prellis Biologics also focuses on accurately replicating the human immune response through lymph node organoids, which can be utilized for various applications such as antibody discovery and immunogenicity assessment. By addressing critical issues in early-stage drug development and translational pharmacology, Prellis Biologics seeks to improve patient outcomes in healthcare.

QuantumCyte, Inc. is a technology platform company based in Sunnyvale, California, that specializes in cell analysis systems aimed at predicting drug efficacy and improving cancer treatment outcomes. Founded in 2014, QuantumCyte develops automated microdissection solutions for molecular pathology, utilizing digital tissue maps to isolate regions of interest that contain important biomarkers. By harnessing artificial intelligence in digital pathology, the company enables healthcare providers to perform precise single-cell analysis, enhancing the understanding of immune system and cancer biology.

Avisa Myko Inc. is a biotechnology company based in San Francisco, California, specializing in the production of natural, water-soluble melanin. The company has developed a patented technology that allows for the large-scale and cost-effective manufacturing of melanin, which is used across various industries, including cosmetics, biomedicine, and environmental applications. Avisa Myko's melanin offers protection against ionizing radiation and is integrated into products such as latex, fabrics, laminated plastics, and glass. Additionally, the company is working on formulating a sunscreen that utilizes melanin as a natural ultraviolet blocker, eliminating the need for traditional chemical or mineral UV filters. By focusing on sustainable solutions, Avisa Myko aims to enhance human health and environmental safety through its innovative melanin products.

California Cultured is a food company based in Davis, California, that specializes in producing sustainable, lab-grown cocoa through advanced cellular agriculture techniques. Founded in 2020, the company aims to create cocoa that is less bitter and requires less sugar, enhancing the taste while promoting health benefits. By stimulating cocoa cells with common food ingredients, California Cultured ensures the growth of premium-quality cocoa without the ethical and environmental issues associated with traditional cocoa production, such as slavery and deforestation. This innovative approach allows customers to enjoy delicious cocoa products that are both sustainable and socially responsible.

AlkaLi Labs is a biotechnology research company based in San Francisco, California, established in 2023. The company focuses on developing biological solutions to harness domestic mineral resources. Currently operating in stealth mode, AlkaLi Labs aims to innovate in the field of biotechnology, leveraging biological processes to unlock valuable minerals.

Geltor, Inc. is a biodesign company based in San Leandro, California, that specializes in producing bioactive, animal-free collagens and proteins for various applications in beauty, nutrition, and wellness. Established in 2015, Geltor offers innovative products such as Collume, which promotes skincare cellular regeneration and dermal synthesis, and HumaColl21, which enhances skin health by boosting collagen and elastin levels. Additionally, the company provides vegan collagen peptides and other novel proteins designed for functional food and nutraceutical formulations. Geltor's products are sustainably cultivated and clinically validated, allowing businesses to create effective, plant-based solutions that contribute to a more sustainable future.

Stämm Biotech is a San Francisco-based company specializing in advanced bioproduction systems designed to address the scaling challenges in the biotech industry. Founded in 2014, Stämm has developed an innovative biomanufacturing solution that integrates microfluidics, electroporation, and robotics, resulting in a compact, all-in-one Bioprocessor. This system has demonstrated productivity levels at least 70 times greater than traditional bioreactors, enabling clients to miniaturize bioreactors and optimize conditions more efficiently. Stämm's technology incorporates various sensors to monitor biological, physical, and chemical variations throughout the bioprocess, facilitating a streamlined approach to microbial growth and monoclonal cell line development. By transforming large-scale biotech operations into a more manageable micro-factory network, Stämm aims to unlock significant market potential in the coming years.

DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, DNALite utilizes innovative oral lipid nanoparticle technology to deliver mRNA and pDNA directly to intestinal stem cells. This approach targets the underlying causes of diseases such as Familial Adenomatous Polyposis, a hereditary form of colorectal cancer that often necessitates invasive surgeries in adolescents. By enabling the intestinal tract to secrete therapeutic proteins into the bloodstream, DNALite aims to transform conventional protein biologics into oral medications, potentially improving patient outcomes and accessibility to treatment.

Michroma Corporation is a biotechnology company that specializes in producing natural thermostable colorants derived from filamentous fungi through a fermentation process. Founded in 2019 and based in both San Francisco, California, and Rosario, Argentina, Michroma aims to replace synthetic pigments and those sourced from animals and plants with sustainable, naturally produced alternatives. The company harnesses synthetic biology to develop proprietary fungal strains that generate high-performance ingredients in bioreactors. Currently, Michroma is prototyping its innovative pH-stable and heat-stable food colorants in collaboration with leading food and beverage and cosmetic companies. Additionally, the company is exploring the production of mycoprotein and other ingredients, making strides in the sustainable ingredients market.

Prolific Machines is a biotechnology company based in San Francisco, California, founded in 2020. It specializes in developing advanced cell technologies aimed at transforming the production of cells for sustainable applications, particularly in the cultivated meat industry. The company focuses on high-scale precision cell-differentiation techniques that enhance the efficiency, quality, reproducibility, and sustainability of cell production. Additionally, Prolific Machines is engaged in research and development efforts related to clean meat and cell therapies, utilizing innovative approaches to create better sustainable options. Through its work, the company aims to promote a healthier future for both humanity and the planet.

Aja Labs is a biotechnology company founded in 2019 and based in San Francisco, California. The company specializes in producing biodegradable fiber designed to replace plastic-based fibers. By utilizing plant materials, Aja Labs creates fiber that mimics the appearance and texture of human hair, providing a sustainable alternative to chemical-laden synthetic fibers and human hair in the production of hair extensions. Aja Labs aims to offer innovative solutions that cater to diverse communities while promoting environmental sustainability.

OneSkin Inc. is a biotechnology company focused on developing innovative solutions to enhance skin health and combat aging. Founded by a team of PhDs and longevity scientists, the company has created a proprietary peptide, OS-01, which has been validated to reduce the biological age of skin by minimizing the accumulation of aged cells, enhancing cellular repair, and fortifying the epidermal barrier. OneSkin offers a flagship product, the OS-01 Topical Supplement, which is designed to be suitable for all skin types and is made from high-quality vegan ingredients. In addition to its product line, OneSkin specializes in creating advanced 3D human skin models for research and testing purposes, providing in vitro services to assess the efficacy and safety of cosmetic ingredients without the use of animals. Incorporated in 2016 and based in San Francisco, OneSkin is dedicated to advancing the understanding of skin biology and developing effective anti-aging solutions.

Michroma Corporation is a biotechnology company that specializes in producing natural thermostable colorants derived from filamentous fungi through a fermentation process. Founded in 2019 and based in both San Francisco, California, and Rosario, Argentina, Michroma aims to replace synthetic pigments and those sourced from animals and plants with sustainable, naturally produced alternatives. The company harnesses synthetic biology to develop proprietary fungal strains that generate high-performance ingredients in bioreactors. Currently, Michroma is prototyping its innovative pH-stable and heat-stable food colorants in collaboration with leading food and beverage and cosmetic companies. Additionally, the company is exploring the production of mycoprotein and other ingredients, making strides in the sustainable ingredients market.

Laguna Bio is a biotechnology company based in Berkeley, California, founded in 2022. The company focuses on drug discovery, specifically developing a platform that activates and expands the innate immune system to combat cancer. Laguna Bio specializes in enhancing a specific type of T cell that targets solid tumors, aiming to improve the efficacy of bispecific antibody drugs. By increasing the immune response against these tumors, the company seeks to provide innovative solutions that may help patients survive cancer more effectively.

Melio is a healthcare company based in Santa Clara, California, specializing in blood testing technology aimed at detecting prevalent infections. The company has developed a comprehensive blood test platform that identifies common pathogens responsible for bloodstream infections. Utilizing a patented melting technique followed by detailed analysis, Melio's technology enables quick and accurate identification of blood-based pathogens. This innovation allows healthcare providers to deliver timely and targeted treatment, addressing the urgent need for effective therapies while also contributing to the fight against antibiotic resistance.

Prellis Biologics, Inc. specializes in creating human tissues for drug development and the eventual production of human organs for transplantation. Founded in 2016 and based in San Francisco, California, the company employs advanced bioprinting technology to develop vascularized human tissues and organs, aiming to overcome the challenges associated with microvasculature. Its innovative products include TissueWorkshop, Organoids, Vascular Bundles, Tissue Chips, and Holograph X. Prellis Biologics also focuses on accurately replicating the human immune response through lymph node organoids, which can be utilized for various applications such as antibody discovery and immunogenicity assessment. By addressing critical issues in early-stage drug development and translational pharmacology, Prellis Biologics seeks to improve patient outcomes in healthcare.

SyntheX, Inc. is a biotechnology company based in San Francisco, California, that specializes in drug discovery focused on therapeutic applications, particularly in oncology. Founded in 2016, SyntheX employs a proprietary screening platform that utilizes synthetic biology to expand the druggable proteome. This platform enables the identification of protein interaction modulators through empirical intracellular selection, allowing for the discovery of compounds that can disrupt specific protein-protein interactions or facilitate functional protein degradation. The company's development portfolio includes stabilized peptide therapeutics, such as STX101 and STX105, aimed at treating cancers that utilize homologous recombination for chemotherapy evasion. SyntheX's approach integrates advanced technologies and engineered circuits to create a robust internal pipeline targeting genetically validated therapeutic mechanisms, while also engaging in external discovery collaborations.

BioLumen is a nutritional technology company that develops a patented dietary fiber technology platform that reduces the negative effect of a diet heavy in processed foods. BioLumen's technology is composed of insoluble dietary fiber matrix covered with a blend of food ingredients created from the latest drug delivery system research. The company's product, a nutraceutical, focuses on high risk individuals with prediabetes to help manage blood sugar levels, protect their liver from excess sugar and feed their gut microbiome, delivering health benefits. BioLumen was founded on 2018 and is headquartered in San Francisco, California.

UPSIDE Foods, formerly known as Memphis Meats, is a cultivated meat company founded in 2015 and headquartered in Berkeley, California. The company specializes in producing real meat, poultry, and seafood directly from animal cells, eliminating the need to raise and slaughter animals. This innovative approach significantly reduces the resource consumption associated with traditional meat production, requiring less water, land, and energy. UPSIDE Foods aims to offer consumers clean, humane, and sustainable meat products, such as beef meatballs, chicken, and duck, all grown in controlled environments. The company is led by Dr. Uma Valeti, who is committed to transforming the food industry with healthier and environmentally friendly alternatives to conventional meat.

DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, DNALite utilizes innovative oral lipid nanoparticle technology to deliver mRNA and pDNA directly to intestinal stem cells. This approach targets the underlying causes of diseases such as Familial Adenomatous Polyposis, a hereditary form of colorectal cancer that often necessitates invasive surgeries in adolescents. By enabling the intestinal tract to secrete therapeutic proteins into the bloodstream, DNALite aims to transform conventional protein biologics into oral medications, potentially improving patient outcomes and accessibility to treatment.

Finless Foods Inc. is a biotechnology company based in Emeryville, California, that specializes in producing seafood products for human consumption using cellular-agriculture technologies. Founded in 2017, the company focuses on growing marine-animal cells to create alternatives to traditional fish and seafood, including bluefin tuna. By offering a variety of responsibly produced food options, Finless Foods aims to cater to diverse tastes and dietary needs while promoting sustainability and better ocean health. The company's innovative approach provides consumers with healthy and accessible seafood alternatives, enabling them to maintain a balanced diet without compromising on flavor or variety.

QuantumCyte, Inc. is a technology platform company based in Sunnyvale, California, that specializes in cell analysis systems aimed at predicting drug efficacy and improving cancer treatment outcomes. Founded in 2014, QuantumCyte develops automated microdissection solutions for molecular pathology, utilizing digital tissue maps to isolate regions of interest that contain important biomarkers. By harnessing artificial intelligence in digital pathology, the company enables healthcare providers to perform precise single-cell analysis, enhancing the understanding of immune system and cancer biology.

Avisa Myko Inc. is a biotechnology company based in San Francisco, California, specializing in the production of natural, water-soluble melanin. The company has developed a patented technology that allows for the large-scale and cost-effective manufacturing of melanin, which is used across various industries, including cosmetics, biomedicine, and environmental applications. Avisa Myko's melanin offers protection against ionizing radiation and is integrated into products such as latex, fabrics, laminated plastics, and glass. Additionally, the company is working on formulating a sunscreen that utilizes melanin as a natural ultraviolet blocker, eliminating the need for traditional chemical or mineral UV filters. By focusing on sustainable solutions, Avisa Myko aims to enhance human health and environmental safety through its innovative melanin products.

Sóliome is a biotechnology company founded in 2021 and based in San Francisco, California. The company specializes in developing protein-based sunscreens designed to be safe for both the skin and the environment. These innovative products aim to reduce inflammation and skin damage caused by traditional sunscreens, which often contain harmful xenobiotic ingredients that can absorb into the skin and contribute to ecological harm. Sóliome's approach allows customers to protect their skin from harmful rays without the adverse effects associated with conventional sunscreen formulations.

Sóliome is a biotechnology company founded in 2021 and based in San Francisco, California. The company specializes in developing protein-based sunscreens designed to be safe for both the skin and the environment. These innovative products aim to reduce inflammation and skin damage caused by traditional sunscreens, which often contain harmful xenobiotic ingredients that can absorb into the skin and contribute to ecological harm. Sóliome's approach allows customers to protect their skin from harmful rays without the adverse effects associated with conventional sunscreen formulations.

ZymoChem, Inc. is a biotechnology company based in Emeryville, California, founded in 2013. It specializes in the development of eco-friendly chemicals and bioprocesses using engineered microbes to convert renewable feedstocks, such as sugars, into industrial chemicals. The company’s bio-manufacturing platform aims to produce bio-based materials while minimizing carbon emissions during production, thereby supporting a carbon-efficient economy. By establishing cost-effective bioprocesses and novel biosynthetic pathways, ZymoChem enables clients to reduce production costs and enhance their competitiveness in the market. Through its innovative approach, the company contributes to sustainable manufacturing practices and the advancement of a real-zero economy.

Lingrove, LLC is a manufacturer of bio-composite materials based in San Francisco, California, founded in 2014. The company specializes in high-performance natural fiber composites made from plant-based materials, utilizing a proprietary process to create products that mimic the appearance and properties of wood. Its flagship product, Ekoa, combines flax linen fibers with resin derived from industrial waste, and is primarily used in the production of musical instruments, as well as in the furniture, transportation, and construction industries. Lingrove aims to address the challenges posed by diminishing wood supplies and seeks to reduce deforestation and the carbon footprint associated with the built environment by offering sustainable, carbon-negative alternatives.

New Culture is a food and beverage company based in San Francisco, California, founded in 2018. The company specializes in producing animal-free cheese using innovative methods that involve microflora to create dairy proteins. By focusing on sustainable and ethical practices, New Culture aims to revolutionize the cheese-making process, offering a variety of delicious and healthy cheese alternatives. Their products are designed to reduce dependency on animal agriculture while providing consumers with access to nutritious dairy-like options.

Sundial Foods, founded in 2019 and headquartered in Berkeley, California, specializes in creating plant-based meat alternatives aimed at environmentally conscious consumers. The company employs a macro and microstructural engineering approach to develop products that closely mimic the look, texture, and taste of traditional meat, all while ensuring affordability and nutritional value. By utilizing familiar ingredients and straightforward production processes, Sundial Foods strives to make plant-based meats accessible to a wider audience. The company's mission is to encourage a shift towards sustainable eating habits, thereby reducing meat consumption and its associated environmental impacts.

Prothegen is a biotechnology company located in Palo Alto, California, focused on developing innovative medicines that precisely regulate cell death. The company has created a platform aimed at delivering therapies that can inhibit or promote ferroptosis, a form of regulated cell death. By targeting this process, Prothegen seeks to provide effective therapeutic options for patients, enhancing the treatment of conditions associated with uncontrolled cell death.

Prothegen is a biotechnology company located in Palo Alto, California, focused on developing innovative medicines that precisely regulate cell death. The company has created a platform aimed at delivering therapies that can inhibit or promote ferroptosis, a form of regulated cell death. By targeting this process, Prothegen seeks to provide effective therapeutic options for patients, enhancing the treatment of conditions associated with uncontrolled cell death.

California Cultured is a food company based in Davis, California, that specializes in producing sustainable, lab-grown cocoa through advanced cellular agriculture techniques. Founded in 2020, the company aims to create cocoa that is less bitter and requires less sugar, enhancing the taste while promoting health benefits. By stimulating cocoa cells with common food ingredients, California Cultured ensures the growth of premium-quality cocoa without the ethical and environmental issues associated with traditional cocoa production, such as slavery and deforestation. This innovative approach allows customers to enjoy delicious cocoa products that are both sustainable and socially responsible.

Indee Labs specializes in developing innovative hardware for gene delivery, focusing on a non-viral intracellular delivery system. This technology facilitates the efficient development and scalable manufacture of gene-modified cell therapies, including chimeric antigen receptor T cells. By employing microfluidic vortex shedding, the system enables the gentle delivery of constructs such as nucleic acids, proteins, and gene-editing complexes to a variety of cell types, ensuring maximum recovery of viable, modified cells with minimal disruption. Indee Labs collaborates with the Australian National Fabrication Facility and has established its presence with offices in Sydney and lab space at Bonneville Labs in Berkeley. The company is recognized for its contributions to the field, having affiliations with NSW Health, IndieBio, Y Combinator, and MBC Biolabs.

Khepra is a company based in San Francisco, California, that focuses on transforming plastics and agricultural waste into renewable fuels using innovative technology. The company employs a proprietary process that combines ultrasonic technology, frictive heating, cavitation, and acoustic pressure to efficiently break down waste streams. This method utilizes excess renewable electricity generated from solar and wind sources, particularly during times of low energy generation or curtailment. By converting waste into drop-in fuels and renewable chemicals without extraction, Khepra aims to support industries in their transition towards cleaner energy solutions and promote sustainability.

Finless Foods Inc. is a biotechnology company based in Emeryville, California, that specializes in producing seafood products for human consumption using cellular-agriculture technologies. Founded in 2017, the company focuses on growing marine-animal cells to create alternatives to traditional fish and seafood, including bluefin tuna. By offering a variety of responsibly produced food options, Finless Foods aims to cater to diverse tastes and dietary needs while promoting sustainability and better ocean health. The company's innovative approach provides consumers with healthy and accessible seafood alternatives, enabling them to maintain a balanced diet without compromising on flavor or variety.

Filtricine, Inc. is a clinical-stage biotechnology company based in Santa Clara, California, focused on developing therapeutic products for cancer treatment. Founded in 2017, the company specializes in a novel nutrient modulation platform that targets and depletes essential nutrients critical for cancer cell growth. By exploiting the metabolic vulnerabilities of cancer cells, Filtricine aims to halt the spread of cancer without relying on traditional drug substances. This approach allows healthcare professionals to utilize targeted nutrient deprivation therapy to address a broad spectrum of cancers effectively.

QuantumCyte, Inc. is a technology platform company based in Sunnyvale, California, that specializes in cell analysis systems aimed at predicting drug efficacy and improving cancer treatment outcomes. Founded in 2014, QuantumCyte develops automated microdissection solutions for molecular pathology, utilizing digital tissue maps to isolate regions of interest that contain important biomarkers. By harnessing artificial intelligence in digital pathology, the company enables healthcare providers to perform precise single-cell analysis, enhancing the understanding of immune system and cancer biology.

Stämm Biotech is a San Francisco-based company specializing in advanced bioproduction systems designed to address the scaling challenges in the biotech industry. Founded in 2014, Stämm has developed an innovative biomanufacturing solution that integrates microfluidics, electroporation, and robotics, resulting in a compact, all-in-one Bioprocessor. This system has demonstrated productivity levels at least 70 times greater than traditional bioreactors, enabling clients to miniaturize bioreactors and optimize conditions more efficiently. Stämm's technology incorporates various sensors to monitor biological, physical, and chemical variations throughout the bioprocess, facilitating a streamlined approach to microbial growth and monoclonal cell line development. By transforming large-scale biotech operations into a more manageable micro-factory network, Stämm aims to unlock significant market potential in the coming years.

Sundial Foods, founded in 2019 and headquartered in Berkeley, California, specializes in creating plant-based meat alternatives aimed at environmentally conscious consumers. The company employs a macro and microstructural engineering approach to develop products that closely mimic the look, texture, and taste of traditional meat, all while ensuring affordability and nutritional value. By utilizing familiar ingredients and straightforward production processes, Sundial Foods strives to make plant-based meats accessible to a wider audience. The company's mission is to encourage a shift towards sustainable eating habits, thereby reducing meat consumption and its associated environmental impacts.

Sundial Foods, founded in 2019 and headquartered in Berkeley, California, specializes in creating plant-based meat alternatives aimed at environmentally conscious consumers. The company employs a macro and microstructural engineering approach to develop products that closely mimic the look, texture, and taste of traditional meat, all while ensuring affordability and nutritional value. By utilizing familiar ingredients and straightforward production processes, Sundial Foods strives to make plant-based meats accessible to a wider audience. The company's mission is to encourage a shift towards sustainable eating habits, thereby reducing meat consumption and its associated environmental impacts.

DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, DNALite utilizes innovative oral lipid nanoparticle technology to deliver mRNA and pDNA directly to intestinal stem cells. This approach targets the underlying causes of diseases such as Familial Adenomatous Polyposis, a hereditary form of colorectal cancer that often necessitates invasive surgeries in adolescents. By enabling the intestinal tract to secrete therapeutic proteins into the bloodstream, DNALite aims to transform conventional protein biologics into oral medications, potentially improving patient outcomes and accessibility to treatment.

Prolific Machines is a biotechnology company based in San Francisco, California, founded in 2020. It specializes in developing advanced cell technologies aimed at transforming the production of cells for sustainable applications, particularly in the cultivated meat industry. The company focuses on high-scale precision cell-differentiation techniques that enhance the efficiency, quality, reproducibility, and sustainability of cell production. Additionally, Prolific Machines is engaged in research and development efforts related to clean meat and cell therapies, utilizing innovative approaches to create better sustainable options. Through its work, the company aims to promote a healthier future for both humanity and the planet.

Chronus Health, Inc. is a company that specializes in developing a portable diagnostic platform aimed at delivering rapid point-of-care lab results, specifically for complete blood count and comprehensive metabolic panel tests. Founded in 2017 and based in Mountain View, California, the company's innovative system utilizes microfluidics and semiconductor technology, combined with data analytics, to provide healthcare providers with real-time test results. This capability allows for immediate diagnosis at the point of care, enhancing the efficiency of treatment and significantly improving patient outcomes. By enabling doctors to obtain lab results in minutes, Chronus Health facilitates timely decision-making in clinical settings.

Aja Labs is a biotechnology company founded in 2019 and based in San Francisco, California. The company specializes in producing biodegradable fiber designed to replace plastic-based fibers. By utilizing plant materials, Aja Labs creates fiber that mimics the appearance and texture of human hair, providing a sustainable alternative to chemical-laden synthetic fibers and human hair in the production of hair extensions. Aja Labs aims to offer innovative solutions that cater to diverse communities while promoting environmental sustainability.

Dalton Bioanalytics specializes in developing advanced analytical technology aimed at transforming blood analysis into a more efficient and cost-effective process. By digitizing the biochemical composition of blood, the company provides a comprehensive array of actionable health insights, addressing the limitations of traditional laboratory testing. This technology enables the monitoring of various plasma analytes, including proteins, lipids, electrolytes, and small molecules, through a single assay. Dalton Bioanalytics supports the scientific research community in exploring multi-omic biology, thereby facilitating the discovery, development, and delivery of precision medicine. Founded in 2019, the company is headquartered in Los Angeles, California.

California Cultured is a food company based in Davis, California, that specializes in producing sustainable, lab-grown cocoa through advanced cellular agriculture techniques. Founded in 2020, the company aims to create cocoa that is less bitter and requires less sugar, enhancing the taste while promoting health benefits. By stimulating cocoa cells with common food ingredients, California Cultured ensures the growth of premium-quality cocoa without the ethical and environmental issues associated with traditional cocoa production, such as slavery and deforestation. This innovative approach allows customers to enjoy delicious cocoa products that are both sustainable and socially responsible.

Lingrove, LLC is a manufacturer of bio-composite materials based in San Francisco, California, founded in 2014. The company specializes in high-performance natural fiber composites made from plant-based materials, utilizing a proprietary process to create products that mimic the appearance and properties of wood. Its flagship product, Ekoa, combines flax linen fibers with resin derived from industrial waste, and is primarily used in the production of musical instruments, as well as in the furniture, transportation, and construction industries. Lingrove aims to address the challenges posed by diminishing wood supplies and seeks to reduce deforestation and the carbon footprint associated with the built environment by offering sustainable, carbon-negative alternatives.

Microgenesis is a biotechnology company focused on improving fertility and pregnancy health through innovative diagnostic and treatment solutions. It offers a non-invasive fertility test that identifies subclinical inflammation affecting ovarian function and implantation, particularly beneficial for women who have experienced multiple IVF failures. The company's personalized nutritional supplementation aims to restore fertility potential in women, utilizing all-natural and drug-free methods. Operating out of a CLIA-certified lab in Oakland, Microgenesis is expanding its services to obstetricians and gynecologists, as well as direct-to-consumer markets. In addition to its fertility test, the company provides tools to analyze microbiota imbalances linked to infertility and immunological issues, thus addressing complex reproductive health cases comprehensively.

SyntheX, Inc. is a biotechnology company based in San Francisco, California, that specializes in drug discovery focused on therapeutic applications, particularly in oncology. Founded in 2016, SyntheX employs a proprietary screening platform that utilizes synthetic biology to expand the druggable proteome. This platform enables the identification of protein interaction modulators through empirical intracellular selection, allowing for the discovery of compounds that can disrupt specific protein-protein interactions or facilitate functional protein degradation. The company's development portfolio includes stabilized peptide therapeutics, such as STX101 and STX105, aimed at treating cancers that utilize homologous recombination for chemotherapy evasion. SyntheX's approach integrates advanced technologies and engineered circuits to create a robust internal pipeline targeting genetically validated therapeutic mechanisms, while also engaging in external discovery collaborations.

Finless Foods Inc. is a biotechnology company based in Emeryville, California, that specializes in producing seafood products for human consumption using cellular-agriculture technologies. Founded in 2017, the company focuses on growing marine-animal cells to create alternatives to traditional fish and seafood, including bluefin tuna. By offering a variety of responsibly produced food options, Finless Foods aims to cater to diverse tastes and dietary needs while promoting sustainability and better ocean health. The company's innovative approach provides consumers with healthy and accessible seafood alternatives, enabling them to maintain a balanced diet without compromising on flavor or variety.

OneSkin Inc. is a biotechnology company focused on developing innovative solutions to enhance skin health and combat aging. Founded by a team of PhDs and longevity scientists, the company has created a proprietary peptide, OS-01, which has been validated to reduce the biological age of skin by minimizing the accumulation of aged cells, enhancing cellular repair, and fortifying the epidermal barrier. OneSkin offers a flagship product, the OS-01 Topical Supplement, which is designed to be suitable for all skin types and is made from high-quality vegan ingredients. In addition to its product line, OneSkin specializes in creating advanced 3D human skin models for research and testing purposes, providing in vitro services to assess the efficacy and safety of cosmetic ingredients without the use of animals. Incorporated in 2016 and based in San Francisco, OneSkin is dedicated to advancing the understanding of skin biology and developing effective anti-aging solutions.

Advanced Microbubbles Inc specializes in developing microbubbles as ultrasound contrast agents for targeted drug delivery, particularly in overcoming significant biological barriers like the blood-brain barrier and tumor endothelium. Founded in 2020 and based in Newark, California, the company offers a range of products including size-isolated microbubbles, polydisperse microbubbles, and biotin- or streptavidin-tagged variants. These microbubbles are agitated with ultrasound at the tumor site, facilitating the local delivery of drugs by temporarily opening barriers that typically hinder treatment. By enabling more effective drug delivery, Advanced Microbubbles aims to reduce side effects and improve survival outcomes for patients with various neurological conditions and cancer.

Advanced Microbubbles Inc specializes in developing microbubbles as ultrasound contrast agents for targeted drug delivery, particularly in overcoming significant biological barriers like the blood-brain barrier and tumor endothelium. Founded in 2020 and based in Newark, California, the company offers a range of products including size-isolated microbubbles, polydisperse microbubbles, and biotin- or streptavidin-tagged variants. These microbubbles are agitated with ultrasound at the tumor site, facilitating the local delivery of drugs by temporarily opening barriers that typically hinder treatment. By enabling more effective drug delivery, Advanced Microbubbles aims to reduce side effects and improve survival outcomes for patients with various neurological conditions and cancer.

Khepra is a company based in San Francisco, California, that focuses on transforming plastics and agricultural waste into renewable fuels using innovative technology. The company employs a proprietary process that combines ultrasonic technology, frictive heating, cavitation, and acoustic pressure to efficiently break down waste streams. This method utilizes excess renewable electricity generated from solar and wind sources, particularly during times of low energy generation or curtailment. By converting waste into drop-in fuels and renewable chemicals without extraction, Khepra aims to support industries in their transition towards cleaner energy solutions and promote sustainability.

Khepra is a company based in San Francisco, California, that focuses on transforming plastics and agricultural waste into renewable fuels using innovative technology. The company employs a proprietary process that combines ultrasonic technology, frictive heating, cavitation, and acoustic pressure to efficiently break down waste streams. This method utilizes excess renewable electricity generated from solar and wind sources, particularly during times of low energy generation or curtailment. By converting waste into drop-in fuels and renewable chemicals without extraction, Khepra aims to support industries in their transition towards cleaner energy solutions and promote sustainability.

Convalesce Inc. is a therapeutic company based in San Francisco, California, focused on developing stem cell-based therapies for neurodegenerative conditions, particularly Parkinson's disease. Founded in 2018, Convalesce utilizes advanced biomaterials to enhance the efficacy of stem cell treatments. Their innovative implantable biomaterials aim to improve stem cell survival and facilitate the differentiation of these cells into neurons after implantation. By addressing critical challenges in stem cell therapy, Convalesce seeks to enable healthcare professionals to regenerate neuronal networks lost due to degeneration, ultimately offering new hope for patients suffering from debilitating neurological disorders.

Dalton Bioanalytics specializes in developing advanced analytical technology aimed at transforming blood analysis into a more efficient and cost-effective process. By digitizing the biochemical composition of blood, the company provides a comprehensive array of actionable health insights, addressing the limitations of traditional laboratory testing. This technology enables the monitoring of various plasma analytes, including proteins, lipids, electrolytes, and small molecules, through a single assay. Dalton Bioanalytics supports the scientific research community in exploring multi-omic biology, thereby facilitating the discovery, development, and delivery of precision medicine. Founded in 2019, the company is headquartered in Los Angeles, California.

Prellis Biologics, Inc. specializes in creating human tissues for drug development and the eventual production of human organs for transplantation. Founded in 2016 and based in San Francisco, California, the company employs advanced bioprinting technology to develop vascularized human tissues and organs, aiming to overcome the challenges associated with microvasculature. Its innovative products include TissueWorkshop, Organoids, Vascular Bundles, Tissue Chips, and Holograph X. Prellis Biologics also focuses on accurately replicating the human immune response through lymph node organoids, which can be utilized for various applications such as antibody discovery and immunogenicity assessment. By addressing critical issues in early-stage drug development and translational pharmacology, Prellis Biologics seeks to improve patient outcomes in healthcare.

Circularis Biotechnologies, Inc. is a biotechnology company focused on developing innovative methods to regulate gene expression, aiming to enhance the production yields of biotherapeutics. Founded in 2014 and based in Oakland, California, the company offers a range of products and services, including RACRE Variant Libraries, hCMV Variant Library, Protein expression with CMV promoters, and T7 Variant Library. Additionally, Circularis provides services such as RACRE Enhancement, RACRE Discovery, RACRE Technology Access Program, and Ribozyme Analysis of Cis-Regulatory Elements. Through its technology, Circularis Biotechnologies seeks to advance the capabilities of biotherapeutic production in the industry.

CASPR Biotech, founded in 2018 and located in San Francisco, California, specializes in the development of a CRISPR-based platform for diagnosing antimicrobial resistances (AMR) and infectious diseases. The company creates portable diagnostic kits that enable the detection of specific DNA and RNA sequences, as well as signature amino acid sequences associated with infectious diseases and genetic mutations. These kits aim to provide healthcare professionals with a simple, rapid, and cost-effective solution for molecular detection, enhancing the accuracy and efficiency of clinical diagnostics.

CASPR Biotech, founded in 2018 and located in San Francisco, California, specializes in the development of a CRISPR-based platform for diagnosing antimicrobial resistances (AMR) and infectious diseases. The company creates portable diagnostic kits that enable the detection of specific DNA and RNA sequences, as well as signature amino acid sequences associated with infectious diseases and genetic mutations. These kits aim to provide healthcare professionals with a simple, rapid, and cost-effective solution for molecular detection, enhancing the accuracy and efficiency of clinical diagnostics.

UPSIDE Foods, formerly known as Memphis Meats, is a cultivated meat company founded in 2015 and headquartered in Berkeley, California. The company specializes in producing real meat, poultry, and seafood directly from animal cells, eliminating the need to raise and slaughter animals. This innovative approach significantly reduces the resource consumption associated with traditional meat production, requiring less water, land, and energy. UPSIDE Foods aims to offer consumers clean, humane, and sustainable meat products, such as beef meatballs, chicken, and duck, all grown in controlled environments. The company is led by Dr. Uma Valeti, who is committed to transforming the food industry with healthier and environmentally friendly alternatives to conventional meat.

Chronus Health, Inc. is a company that specializes in developing a portable diagnostic platform aimed at delivering rapid point-of-care lab results, specifically for complete blood count and comprehensive metabolic panel tests. Founded in 2017 and based in Mountain View, California, the company's innovative system utilizes microfluidics and semiconductor technology, combined with data analytics, to provide healthcare providers with real-time test results. This capability allows for immediate diagnosis at the point of care, enhancing the efficiency of treatment and significantly improving patient outcomes. By enabling doctors to obtain lab results in minutes, Chronus Health facilitates timely decision-making in clinical settings.

BioLumen is a nutritional technology company that develops a patented dietary fiber technology platform that reduces the negative effect of a diet heavy in processed foods. BioLumen's technology is composed of insoluble dietary fiber matrix covered with a blend of food ingredients created from the latest drug delivery system research. The company's product, a nutraceutical, focuses on high risk individuals with prediabetes to help manage blood sugar levels, protect their liver from excess sugar and feed their gut microbiome, delivering health benefits. BioLumen was founded on 2018 and is headquartered in San Francisco, California.

Primitives is a public benefit company based in San Francisco, California, specializing in the engineering of advanced biomaterials aimed at mitigating food waste and plastic pollution. The company focuses on manufacturing biodegradable plastics that are designed to help users reduce their environmental impact. Primitives develops environmentally sustainable materials that can be adapted for various applications, producing bioplastic products with innovative properties such as advanced sensing, display capabilities, and enhanced biodegradation. Through its efforts, Primitives seeks to provide effective solutions for businesses looking to address the challenges of plastic pollution.

Primitives is a public benefit company based in San Francisco, California, specializing in the engineering of advanced biomaterials aimed at mitigating food waste and plastic pollution. The company focuses on manufacturing biodegradable plastics that are designed to help users reduce their environmental impact. Primitives develops environmentally sustainable materials that can be adapted for various applications, producing bioplastic products with innovative properties such as advanced sensing, display capabilities, and enhanced biodegradation. Through its efforts, Primitives seeks to provide effective solutions for businesses looking to address the challenges of plastic pollution.

Blue Planet Ecosystems Incorporated, founded in 2018 and based in San Francisco, California, specializes in the development and operation of modular closed-loop photoprotein reactors that facilitate sustainable food production, particularly seafood, in extreme environments. The company's innovative technology mimics natural aquatic ecosystems, allowing for the conversion of sunlight and carbon dioxide into essential nutrients such as sugars, amino acids, and fatty acids. This process supports the production of organic seafood close to consumers, promoting a more efficient and environmentally friendly approach to aquaculture. By enabling farmers and agricultural businesses to diversify their methods, Blue Planet Ecosystems aims to address the challenges posed by climate change and enhance food security.

Michroma Corporation is a biotechnology company that specializes in producing natural thermostable colorants derived from filamentous fungi through a fermentation process. Founded in 2019 and based in both San Francisco, California, and Rosario, Argentina, Michroma aims to replace synthetic pigments and those sourced from animals and plants with sustainable, naturally produced alternatives. The company harnesses synthetic biology to develop proprietary fungal strains that generate high-performance ingredients in bioreactors. Currently, Michroma is prototyping its innovative pH-stable and heat-stable food colorants in collaboration with leading food and beverage and cosmetic companies. Additionally, the company is exploring the production of mycoprotein and other ingredients, making strides in the sustainable ingredients market.

Avisa Myko Inc. is a biotechnology company based in San Francisco, California, specializing in the production of natural, water-soluble melanin. The company has developed a patented technology that allows for the large-scale and cost-effective manufacturing of melanin, which is used across various industries, including cosmetics, biomedicine, and environmental applications. Avisa Myko's melanin offers protection against ionizing radiation and is integrated into products such as latex, fabrics, laminated plastics, and glass. Additionally, the company is working on formulating a sunscreen that utilizes melanin as a natural ultraviolet blocker, eliminating the need for traditional chemical or mineral UV filters. By focusing on sustainable solutions, Avisa Myko aims to enhance human health and environmental safety through its innovative melanin products.

Dalton Bioanalytics specializes in developing advanced analytical technology aimed at transforming blood analysis into a more efficient and cost-effective process. By digitizing the biochemical composition of blood, the company provides a comprehensive array of actionable health insights, addressing the limitations of traditional laboratory testing. This technology enables the monitoring of various plasma analytes, including proteins, lipids, electrolytes, and small molecules, through a single assay. Dalton Bioanalytics supports the scientific research community in exploring multi-omic biology, thereby facilitating the discovery, development, and delivery of precision medicine. Founded in 2019, the company is headquartered in Los Angeles, California.

Pando Nutrition, Inc. is an animal microbiome company focused on developing innovative probiotics to support antibiotic-free livestock production. Based in San Francisco, California, and incorporated in 2017, the company aims to address the antibiotic resistance crisis by utilizing genetically engineered probiotics that enhance livestock health and performance without relying on medically significant drugs. Pando Nutrition offers Panbiotics, a platform designed to identify and control methane emissions, thereby improving feed efficiency and profitability in livestock. Additionally, the company is engaged in the development of solutions for poultry pathogens, such as Coccidiosis. By leveraging advanced biotechnology, Pando Nutrition creates yeast-based systems for animal feed that not only boost animal health and immunity but also enable the production of essential nutrients, contributing to a sustainable and efficient food supply chain.

Dahlia Biosciences is a biotechnology company based in California, founded in 2011. It focuses on DNA analysis and diagnostics, specializing in single-cell RNA analysis tools that are applicable for both research and diagnostic purposes. The company develops RNA detection tools utilizing CRISPR-Cas9 technology, which allows for the detection of multiple DNA and RNA biomarkers directly within cells and tissues. This innovative approach enables scientists to study and isolate cells with high precision and resolution, facilitating advancements in precision medicine research.

Stämm Biotech is a San Francisco-based company specializing in advanced bioproduction systems designed to address the scaling challenges in the biotech industry. Founded in 2014, Stämm has developed an innovative biomanufacturing solution that integrates microfluidics, electroporation, and robotics, resulting in a compact, all-in-one Bioprocessor. This system has demonstrated productivity levels at least 70 times greater than traditional bioreactors, enabling clients to miniaturize bioreactors and optimize conditions more efficiently. Stämm's technology incorporates various sensors to monitor biological, physical, and chemical variations throughout the bioprocess, facilitating a streamlined approach to microbial growth and monoclonal cell line development. By transforming large-scale biotech operations into a more manageable micro-factory network, Stämm aims to unlock significant market potential in the coming years.

DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, DNALite utilizes innovative oral lipid nanoparticle technology to deliver mRNA and pDNA directly to intestinal stem cells. This approach targets the underlying causes of diseases such as Familial Adenomatous Polyposis, a hereditary form of colorectal cancer that often necessitates invasive surgeries in adolescents. By enabling the intestinal tract to secrete therapeutic proteins into the bloodstream, DNALite aims to transform conventional protein biologics into oral medications, potentially improving patient outcomes and accessibility to treatment.

QuantumCyte, Inc. is a technology platform company based in Sunnyvale, California, that specializes in cell analysis systems aimed at predicting drug efficacy and improving cancer treatment outcomes. Founded in 2014, QuantumCyte develops automated microdissection solutions for molecular pathology, utilizing digital tissue maps to isolate regions of interest that contain important biomarkers. By harnessing artificial intelligence in digital pathology, the company enables healthcare providers to perform precise single-cell analysis, enhancing the understanding of immune system and cancer biology.

Chronus Health, Inc. is a company that specializes in developing a portable diagnostic platform aimed at delivering rapid point-of-care lab results, specifically for complete blood count and comprehensive metabolic panel tests. Founded in 2017 and based in Mountain View, California, the company's innovative system utilizes microfluidics and semiconductor technology, combined with data analytics, to provide healthcare providers with real-time test results. This capability allows for immediate diagnosis at the point of care, enhancing the efficiency of treatment and significantly improving patient outcomes. By enabling doctors to obtain lab results in minutes, Chronus Health facilitates timely decision-making in clinical settings.

The EVERY Company, formerly known as Clara Foods, specializes in producing animal-free proteins for the food and beverage industry. Founded in 2014 and based in South San Francisco, California, the company utilizes advanced fermentation technology to create functional and nutritional proteins derived from microorganisms. Its product line includes baking ingredients, nutritional supplements, and egg white alternatives that are free from pathogens and suitable for various culinary applications, such as cakes and meringues. The EVERY Company aims to provide a sustainable, healthier, and kinder alternative to traditional animal agriculture by decoupling protein production from animals, thereby offering consumers healthy and affordable protein options without added sugars.

New Culture is a food and beverage company based in San Francisco, California, founded in 2018. The company specializes in producing animal-free cheese using innovative methods that involve microflora to create dairy proteins. By focusing on sustainable and ethical practices, New Culture aims to revolutionize the cheese-making process, offering a variety of delicious and healthy cheese alternatives. Their products are designed to reduce dependency on animal agriculture while providing consumers with access to nutritious dairy-like options.

Prellis Biologics, Inc. specializes in creating human tissues for drug development and the eventual production of human organs for transplantation. Founded in 2016 and based in San Francisco, California, the company employs advanced bioprinting technology to develop vascularized human tissues and organs, aiming to overcome the challenges associated with microvasculature. Its innovative products include TissueWorkshop, Organoids, Vascular Bundles, Tissue Chips, and Holograph X. Prellis Biologics also focuses on accurately replicating the human immune response through lymph node organoids, which can be utilized for various applications such as antibody discovery and immunogenicity assessment. By addressing critical issues in early-stage drug development and translational pharmacology, Prellis Biologics seeks to improve patient outcomes in healthcare.

CASPR Biotech, founded in 2018 and located in San Francisco, California, specializes in the development of a CRISPR-based platform for diagnosing antimicrobial resistances (AMR) and infectious diseases. The company creates portable diagnostic kits that enable the detection of specific DNA and RNA sequences, as well as signature amino acid sequences associated with infectious diseases and genetic mutations. These kits aim to provide healthcare professionals with a simple, rapid, and cost-effective solution for molecular detection, enhancing the accuracy and efficiency of clinical diagnostics.

Guided Clarity, Inc. is a biotechnology company based in San Francisco, California, established in 2018. The company specializes in the development and manufacturing of bioactive peptides aimed at promoting mitochondrial health, particularly for the aging population. Its product line includes medical foods that isolate specific bioactive proteins known for their potential to renew mitochondrial function. Guided Clarity is focused on addressing the health needs associated with aging through innovative nutritional solutions.

Filtricine, Inc. is a clinical-stage biotechnology company based in Santa Clara, California, focused on developing therapeutic products for cancer treatment. Founded in 2017, the company specializes in a novel nutrient modulation platform that targets and depletes essential nutrients critical for cancer cell growth. By exploiting the metabolic vulnerabilities of cancer cells, Filtricine aims to halt the spread of cancer without relying on traditional drug substances. This approach allows healthcare professionals to utilize targeted nutrient deprivation therapy to address a broad spectrum of cancers effectively.

Geltor, Inc. is a biodesign company based in San Leandro, California, that specializes in producing bioactive, animal-free collagens and proteins for various applications in beauty, nutrition, and wellness. Established in 2015, Geltor offers innovative products such as Collume, which promotes skincare cellular regeneration and dermal synthesis, and HumaColl21, which enhances skin health by boosting collagen and elastin levels. Additionally, the company provides vegan collagen peptides and other novel proteins designed for functional food and nutraceutical formulations. Geltor's products are sustainably cultivated and clinically validated, allowing businesses to create effective, plant-based solutions that contribute to a more sustainable future.

Dahlia Biosciences is a biotechnology company based in California, founded in 2011. It focuses on DNA analysis and diagnostics, specializing in single-cell RNA analysis tools that are applicable for both research and diagnostic purposes. The company develops RNA detection tools utilizing CRISPR-Cas9 technology, which allows for the detection of multiple DNA and RNA biomarkers directly within cells and tissues. This innovative approach enables scientists to study and isolate cells with high precision and resolution, facilitating advancements in precision medicine research.

Prime Roots is a San Francisco-based company founded in 2017 that specializes in plant-based food products, particularly meat and seafood alternatives. Utilizing koji mycelium, the company creates vegetarian offerings such as salmon burgers that replicate the taste, texture, and nutrition of traditional meat and seafood. By leveraging natural koji proteins, Prime Roots aims to reduce the reliance on carbon-intensive animal agriculture, providing both meat-eaters and vegans with protein-rich and sustainable food options. In addition to its product offerings, the company also organizes food events for its members.

Stämm Biotech is a San Francisco-based company specializing in advanced bioproduction systems designed to address the scaling challenges in the biotech industry. Founded in 2014, Stämm has developed an innovative biomanufacturing solution that integrates microfluidics, electroporation, and robotics, resulting in a compact, all-in-one Bioprocessor. This system has demonstrated productivity levels at least 70 times greater than traditional bioreactors, enabling clients to miniaturize bioreactors and optimize conditions more efficiently. Stämm's technology incorporates various sensors to monitor biological, physical, and chemical variations throughout the bioprocess, facilitating a streamlined approach to microbial growth and monoclonal cell line development. By transforming large-scale biotech operations into a more manageable micro-factory network, Stämm aims to unlock significant market potential in the coming years.

Convalesce Inc. is a therapeutic company based in San Francisco, California, focused on developing stem cell-based therapies for neurodegenerative conditions, particularly Parkinson's disease. Founded in 2018, Convalesce utilizes advanced biomaterials to enhance the efficacy of stem cell treatments. Their innovative implantable biomaterials aim to improve stem cell survival and facilitate the differentiation of these cells into neurons after implantation. By addressing critical challenges in stem cell therapy, Convalesce seeks to enable healthcare professionals to regenerate neuronal networks lost due to degeneration, ultimately offering new hope for patients suffering from debilitating neurological disorders.

Chronus Health, Inc. is a company that specializes in developing a portable diagnostic platform aimed at delivering rapid point-of-care lab results, specifically for complete blood count and comprehensive metabolic panel tests. Founded in 2017 and based in Mountain View, California, the company's innovative system utilizes microfluidics and semiconductor technology, combined with data analytics, to provide healthcare providers with real-time test results. This capability allows for immediate diagnosis at the point of care, enhancing the efficiency of treatment and significantly improving patient outcomes. By enabling doctors to obtain lab results in minutes, Chronus Health facilitates timely decision-making in clinical settings.

Filtricine, Inc. is a clinical-stage biotechnology company based in Santa Clara, California, focused on developing therapeutic products for cancer treatment. Founded in 2017, the company specializes in a novel nutrient modulation platform that targets and depletes essential nutrients critical for cancer cell growth. By exploiting the metabolic vulnerabilities of cancer cells, Filtricine aims to halt the spread of cancer without relying on traditional drug substances. This approach allows healthcare professionals to utilize targeted nutrient deprivation therapy to address a broad spectrum of cancers effectively.

QuantumCyte, Inc. is a technology platform company based in Sunnyvale, California, that specializes in cell analysis systems aimed at predicting drug efficacy and improving cancer treatment outcomes. Founded in 2014, QuantumCyte develops automated microdissection solutions for molecular pathology, utilizing digital tissue maps to isolate regions of interest that contain important biomarkers. By harnessing artificial intelligence in digital pathology, the company enables healthcare providers to perform precise single-cell analysis, enhancing the understanding of immune system and cancer biology.

Prellis Biologics, Inc. specializes in creating human tissues for drug development and the eventual production of human organs for transplantation. Founded in 2016 and based in San Francisco, California, the company employs advanced bioprinting technology to develop vascularized human tissues and organs, aiming to overcome the challenges associated with microvasculature. Its innovative products include TissueWorkshop, Organoids, Vascular Bundles, Tissue Chips, and Holograph X. Prellis Biologics also focuses on accurately replicating the human immune response through lymph node organoids, which can be utilized for various applications such as antibody discovery and immunogenicity assessment. By addressing critical issues in early-stage drug development and translational pharmacology, Prellis Biologics seeks to improve patient outcomes in healthcare.