IndieBio is an accelerator firm specializing in Synthetic Biology. The firm runs four month accelerator programs for both companies as well as teams with an idea. It prefers to invest in startups that are using biology as the basis of their technology and invests in seed, early stages too. The firm seeks to make investments in life science, biotechnology, and synthetic biology or around the field of Biotech and businesses that use biology to solve a problem and as the basis of their technology, spanning across processes, products, and software. It seeks to invest in ideas and startups based in any geography. The firm prefers to invest $250k through equity investment. It typically makes cash investment of $50k for exchange of eight percent equity in biotech startups and may receive more $25k as Convertible Loan Note if eligible. The firm prefers to invest in teams with two co-founders minimum rather than a single founder. IndieBio was founded in 2014 and is based in San Francisco, California with an additional office in New York, New York.
MAA’VA™ is developing next generation of green building materials that can functionally replace concrete by incorporating recycled plastics, carbon sequestration, and upcycling of manufacturing waste, advancing solutions to river sand shortage crisis, water scarcity crisis, climate change crisis, waste crisis and rapid urbanization.
Pannex Therapeutics is a NY-based biopharma startup pioneering the development of Pannexin 1 channel (Panx1) blockers, a new class of cancer drugs that block multiple pathways to stop growth, spread and survival of cancer cells.
Conan MedTech develops a rapid POC diagnostic test for concussions. The company aims to revolutionize the mild traumatic brain injury diagnosis market to allow sport medicine doctors and athletic coaches and trainers to make a decision on the sideline during a game. Conan MedTech was founded in 2020 and is based in Ithaca, New York.
Avisa Myko is a biotechnology company developing natural soluble melanin for multiple uses that contribute to better health and the environment. The company focused on manufacturing water-soluble, affordable melanin and putting it to use in a wide range of applications that benefit human health and the environment. These applications include, among others, protection against ionizing radiation and electricity generation. Avisa Myko’s patented technology to produce large amounts of soluble melanin puts it at the forefront of true, or eumelanin production. The company's melanin is produced in a dissolved state, extracted to a high level of purity and is easily redissolved, facilitating applications in a variety of industries. It plans to incorporate melanin in materials, such as latex products, fabrics, laminated plastic sheets and glass to protect against harmful radiation. Avisa Myko is based in San Francisco, California.
We are a biotech startup democratizing genomic sequencing applications with proprietary technology. We developed a reliable and robust solution to bring down the cost of applications in long-read sequencers. Our solution consists in a proprietary technology that enables the invention of a myriad of new long-read applications.
Nat4Bio is an agricultural biotechnology company focused on developing naturally-sourced edible coatings to protect fresh produce from spoilage and decay. Utilizing microbial fermentation of selected fungi and bacteria, the company creates cell-free compounds that harness the active principles of these microbes without using the organisms themselves. Their first product is a natural coating for fresh lemons, designed to replace traditional waxes and chemical fungicides. The coating is formulated from a proprietary blend of glucose-based biopolymers and natural antimicrobials, which help guard against microbial pathogens, oxidation, and dehydration. In addition to lemons, Nat4Bio is prototyping similar formulations for blueberries and avocados, with plans to expand its product offerings to cover a wide range of fruit types. By providing a safer and more sustainable alternative to synthetic pesticides and waxes, Nat4Bio aims to enhance the safety, quality, and availability of fresh fruit while reducing food waste.
Cellens is a medical device company that provides clarity and focus on cancer detection. Cellens is a Tufts University spinoff company dedicated to providing patients and doctors with clarity and confidence through noninvasive cancer screening. It was founded in 2019 and is based in Medford, Massachusetts.
ClimateCrop is an agriculture technology company founded in 2021 and based in Ness Ziona. The company specializes in gene editing to enhance the ability of plants to store carbon and energy, thereby increasing crop yields in biomass and fruit production. By improving the resilience of crops to extreme weather conditions, ClimateCrop enables agricultural companies to better adapt to current and future climate challenges, ultimately leading to more sustainable and productive farming practices.
Grand Bio
Convertible Note in 2021
Grand Bio is working to improve the efficiency with which cells create their own growth factors. The firm provides supplements that boost growth factors in the medium in which cells live and thrive.
Sundial Foods utilizes a macro and microstructural engineering approach to create plant-based meat alternatives for conscious consumers. The company is passionate about making the affordable, accessible, and nutritional value of plant-based meats, made from ingredients that customers know and created using simple processes. It is headquartered in Berkeley, California in 2019.
Proton Intelligence provides biomarker monitoring to manage chronic disease and save lives. The first biomarker is potassium, targeting hyperkalemia in chronic kidney disease (CKD) patients who have additional co-morbidities ProtonIntel was founded in 2020 and was headquartered in Vancouver, Canada.
Kyomei develops a meat protein production system using plant cell biology. It uses sustainable ways to add flavor on meat-based alternatives. Kyomei was founded in 2021 and is based in Oxford, England.
Helex, founded in 2021 and based in New York, specializes in developing innovative genomic medicines specifically for renal conditions. The company leverages its proprietary genomics data and bioinformatics platform to create, verify, and distribute therapy-specific guide RNAs (gRNAs). By employing data-driven deep-learning models and high throughput next-generation sequencing data from CRISPR edits on human cell lines, Helex provides reliable predictions and validations in-house. This approach supports clients in expediting the development of CRISPR-based drug discovery and cell and gene therapies, emphasizing non-viral targeted delivery and genome editing for kidney-related therapies.
Finless Foods provides cellular-agriculture technologies to create accessible plant-based and cell-cultured seafood alternatives. Finless Foods offers a variety of food choices that cater to different tastes and dietary requirements. They provide consumers with responsibly produced food items to help them expand their daily eating habits while also contributing to a more sustainable future and promoting better ocean health.
AvantGuard creats innovative solutions that manage surfaces and provide long-term protection against viruses, bacteria, and fungi/mold, in a variety of applications.
Sundial Foods utilizes a macro and microstructural engineering approach to create plant-based meat alternatives for conscious consumers. The company is passionate about making the affordable, accessible, and nutritional value of plant-based meats, made from ingredients that customers know and created using simple processes. It is headquartered in Berkeley, California in 2019.
Proteinea makes biotherapeutics design smarter, safer, and faster by leveraging novel deep-learning models & platforms integrated with smart experimental throughput.
Basin Genomics is combining scientific backgrounds in genomics and oncology with startup expertise to translate genetic discoveries into advances in personalized clinical care as it strives to develop technology that will decrease the rates of cervical cancer globally.
Nyoka Design Labs leverages advances in clean tech to build inspiring, earth-friendly innovations. Starting with the Nyoka Light Wand, a non-toxic glow stick powered with bioluminescence, to prevent the billion toxic, single-use plastic glow sticks that enter our environment every single year.
NovoNutrients is working to turn waste CO2 into high-value, low-cost proteins and additives for food and feed by developing proprietary microbes and advanced gas fermentation systems.
Canaery is focused on developing a neural interface that digitizes the sense of smell to analyze the scent fingerprints of objects. This innovative technology is designed to identify hazardous compounds at critical locations such as ports and inspection points. By utilizing this neurotech device, clients can detect not only the presence of dangerous substances but also gain insights into the nature and condition of the objects being inspected.
California Cultured is a food company creating sustainable, lab-grown cocoa that is less bitter and requires less sugar to be tasty. It produces cocoa intended to provide cocoa that is less bitter and requires less sugar. The company's product entices cocoa cells to grow by stimulation by food ingredients that are found in any grocery store and produce cocoa cells that is good for human health, enabling customers to avail premium quality cocoa products. California Cultured was founded in 2020 and is headquartered in Davis, California.
Cayuga Biotech is a startup developing novel hemostatic drugs and devices to reduce uncontrollable bleeding which is a leading cause of death from traumatic injuries. The company's polyphosphate-based drug accelerates the body's own clotting process to contain clotting at the injury site and thus minimize the risk of side effects. Cayuga is developing drugs for indications that treat traumatic hemorrhage as well as rare bleeding disorders.
Convalesce is a therapeutic company enabling stem cell-based therapy for neurodegenerative conditions like Parkinson's, harnessing state-of-art biomaterials.
Membio's single-use 0.2-10 L benchtop bioreactor system uses a proprietary design to provide a constant environment for cells at all scales. One technique will provide the same outcomes at all scales, whether at 0.2 L, 10 L, or anywhere in between. Fully automated single-use bioreactors designed by the business to enable cost-effective and scalable manufacture.
Carbix transforms atmospheric carbon dioxide into carbonates, which are raw materials for industrial products. Its novel bioreactor captures CO2 from industrial plant flue gas, and in just hours converts CO2 and mineral inputs, into raw materials for construction products and beyond.
This technology marks a start to real-time bacteria detection. Currently, bacteria monitoring is done through manual weekly or monthly samples that are sent to the lab for analysis. Normally, lab analysis takes around 18 - 72 hours until results are available. Ecoli Sense wants to innovate real-time monitoring by making this technology available for bacteria detection.
Chi Botanic creates plant stem cells that we can grow into plant products and ingredients at industrial scale. We generate plant cell cultures representing just the parts or components that we want. Plant cell cultures grow much faster than whole plants. Also, while a fraction of a normal plant makes what we want, our entire cultures can synthesize the desired product. We can grow without the limitations of climate, weather, geography, or season and without fertilizers, pesticides, herbicides with far less water, energy, or shipping requirements to provide safer, and often enhanced natural productsWe make plant stem cells that we can grow into plant products and ingredients at industrial scale. We generate plant cell cultures representing just the parts or components that we want. Plant cell cultures grow much faster than whole plants. Also, while a fraction of a normal plant makes what we want, our entire cultures can synthesize the desired product. We can grow without the limitations of climate, weather, geography, or season and without fertilizers, pesticides, herbicides with far less water, energy, or shipping requirements to provide safer, and often enhanced natural products
Chi Botanic creates plant stem cells that we can grow into plant products and ingredients at industrial scale. We generate plant cell cultures representing just the parts or components that we want. Plant cell cultures grow much faster than whole plants. Also, while a fraction of a normal plant makes what we want, our entire cultures can synthesize the desired product. We can grow without the limitations of climate, weather, geography, or season and without fertilizers, pesticides, herbicides with far less water, energy, or shipping requirements to provide safer, and often enhanced natural productsWe make plant stem cells that we can grow into plant products and ingredients at industrial scale. We generate plant cell cultures representing just the parts or components that we want. Plant cell cultures grow much faster than whole plants. Also, while a fraction of a normal plant makes what we want, our entire cultures can synthesize the desired product. We can grow without the limitations of climate, weather, geography, or season and without fertilizers, pesticides, herbicides with far less water, energy, or shipping requirements to provide safer, and often enhanced natural products
Blue Planet Ecosystems turns sunlight into seafood by replicating aquatic ecosystems. We enable the production of organic seafood close to the consumer on any piece of land. https://www.youtube.com/watch?v=0GkJ8RxfoK4
Avisa Myko is a biotechnology company developing natural soluble melanin for multiple uses that contribute to better health and the environment. The company focused on manufacturing water-soluble, affordable melanin and putting it to use in a wide range of applications that benefit human health and the environment. These applications include, among others, protection against ionizing radiation and electricity generation. Avisa Myko’s patented technology to produce large amounts of soluble melanin puts it at the forefront of true, or eumelanin production. The company's melanin is produced in a dissolved state, extracted to a high level of purity and is easily redissolved, facilitating applications in a variety of industries. It plans to incorporate melanin in materials, such as latex products, fabrics, laminated plastic sheets and glass to protect against harmful radiation. Avisa Myko is based in San Francisco, California.
At Pando Nutrition, Inc. we are solving the antibiotic resistance crisis with genetically engineered probiotics that support livestock health and performance without the use of medically significant drugs.
Membio's single-use 0.2-10 L benchtop bioreactor system uses a proprietary design to provide a constant environment for cells at all scales. One technique will provide the same outcomes at all scales, whether at 0.2 L, 10 L, or anywhere in between. Fully automated single-use bioreactors designed by the business to enable cost-effective and scalable manufacture.
Dahlia Biosciences is a biotechnology company based in California, founded in 2011. It focuses on DNA analysis and diagnostics, specializing in single-cell RNA analysis tools that are applicable for both research and diagnostic purposes. The company develops RNA detection tools utilizing CRISPR-Cas9 technology, which allows for the detection of multiple DNA and RNA biomarkers directly within cells and tissues. This innovative approach enables scientists to study and isolate cells with high precision and resolution, facilitating advancements in precision medicine research.
DNALite Therapeutics is an early-stage preclinical biotechnology company committed to bringing the next generation of drugs to the gastrointestinal tract. It develops oral lipid nanoparticle technology to deliver mRNA and pDNA into the intestine using the oral route of administration. Its drug aims to use the intestinal tract to secrete proteins into the bloodstream turning any protein biologic into an oral drug.
Precision Medicine for Infectious Diseases. Antibiotic Adjuvant is the only system designed to affect 90% of physician hospital antibiotic prescriptions, providing intelligent coordination of heretofore chaotic usage patterns. Antibiotic Adjuvant offers automated resistance control.
Chronus Health is a portable platform that enables doctors to provide real-time treatment based on actual lab results. The company developing a portable CLIA waived system to deliver point-of-care lab results in minutes. It allows for real-time diagnosis at the point-of-care providing lab results in minutes, dramatically improving patient outcomes. Chronus Health was founded in 2017 and is headquartered in Mountain View, California, United States.
NovoNutrients is working to turn waste CO2 into high-value, low-cost proteins and additives for food and feed by developing proprietary microbes and advanced gas fermentation systems.
Electro-Active Technologies LLC is focused on developing a modular system for producing renewable hydrogen from organic waste. Founded in 2017 and headquartered in Knoxville, Tennessee, the company employs a bioelectrochemical process that degrades organic materials into electrons and protons, generating low-cost hydrogen. This innovative approach not only provides a renewable energy source but also addresses environmental concerns, as it offers a carbon-negative pathway to hydrogen production. The company specifically targets food waste, which significantly contributes to global greenhouse gas emissions, as well as high-strength wastewater. By transforming waste into renewable products, Electro-Active Technologies aims to enhance sustainability for businesses and communities alike.
Hexafly they provide breeding and bio-conversion technologies, for protein and oil products for the aquaculture, animal feed and plant nutrition industries.
Convalesce is a therapeutic company enabling stem cell-based therapy for neurodegenerative conditions like Parkinson's, harnessing state-of-art biomaterials.
Prellis Biologics is building human tissues for drug development, and ultimately, developing human organs for transplantation. Bioprinting vascularized human tissue and organs will revolutionize healthcare. Prellis Biologics' technology leverages massive gains in print speed and resolution to break the microvasculature barrier. The company was founded in 2016 and is based in San Francisco, California.
Sun Genomics is a precision nutrition company focused on curing dysbiosis through the gut microflora and personalized solutions. Its flagship product Floré, is a microbiome test and custom synbiotics solution that utilizes whole-genome sequencing to evaluate different digestive system data points and ensure that customers receive a completely personalized product based on their unique gut profiles. The company also offers: Floré Tots, Kids, and Baby, available for kids up to age 0-12, and comes in an easy digestive powder to mix with their favorite drink. Floré Clinical, which is specifically for professional practitioners and their patients. Floré Defense, Balance, and Performance for sports teams and athletes.
sRNAlytics developed a computational platform to diagnose and subtype disease using small RNAs. We offer our technology and services to drug developers to identify companion diagnostics and uncover new therapeutic targets.
Scaled Biolabs is pioneering a Cell Therapy Discovery Engine, working at the frontier of microfluidics, automation, and machine learning to develop best-in-class cell-based medicines. This engine enables leading biotech and pharma companies to survey hundreds of parameters across tens of thousands of experimental processes, providing an unprecedented window into cell-driven biology. This enables the development of novel and optimal cell-based products and processes, simplifying manufacturing, reducing time to market, and improving clinical outcomes. Scaled Biolabs also develops cell therapy assets internally, including a CIRM-funded program focusing on iPSC-derived dopaminergic neurons as a curative cell therapy for Parkinson’s disease.
Our mission is to discover novel therapeutics for diseases with the highest unmet need, pushing the boundaries of drug discovery through innovative and world-class science. Our award-winning small-molecule drug discovery platform uniquely integrates a novel synthesis design strategy, computational modelling, and patient-derived cell-based screening to rapidly and cost-effectively unlock targets considered undruggable using existing approaches. Proteorex’s headquarters are in JLABS @ Toronto, with an office in San Francisco.
Stelvio Oncology is developing a personalized approach to glioblastoma treatment. Their team has core competencies of scientific creativity, clinical excellence and professional management required to successfully commercialize novel drug therapies and precision medicine diagnostics.
NotCo is a food industry. They use technology to recreate the same products. They create food systems. They produce plant-based meat and dairy substitutes. They used artificial intelligence to make plant-based food that functions and animal-based tastes.
Prellis Biologics is building human tissues for drug development, and ultimately, developing human organs for transplantation. Bioprinting vascularized human tissue and organs will revolutionize healthcare. Prellis Biologics' technology leverages massive gains in print speed and resolution to break the microvasculature barrier. The company was founded in 2016 and is based in San Francisco, California.
NeuroQore is comprised of a team of passionate and motivated scientists, engineers, and clinicians dedicated to developing pioneering neuromodulation treatments for various neurobehavioral conditions. We collaborate with world-class universities and research clinics, in order to investigate ways to transform lives. At NeuroQore, we strive to create a world with effective solutions to devastating disorders: major depressive disorder and suicidality.
AnimalBiome provides personalized nutrition services rooted in the science of the microbiome to improve the gut health of dogs and cats. AnimalBiome’s microbiome tests characterize the gut microbiome of individual pets to help provide useful nutrition recommendations, and its restorative supplements are made with material sourced directly from healthy pets to introduce missing beneficial microbes and balance the microbiome.
Ria Health is an online platform that offers telehealth services for individuals seeking to change their relationship with alcohol, providing personalized treatment plans, access to licensed healthcare professionals, and support through digital tools and resources for alcohol use disorder. The platform includes medication-assisted treatment options, behavioral therapies, and continuous monitoring to help users track their progress and maintain accountability. Additionally, Ria Health features a mobile app that allows users to access educational materials, connect with support groups, and communicate with care teams, ensuring a comprehensive approach to managing alcohol consumption and promoting healthier habits.
Mendel is a clinical AI platform for life sciences and healthcare organizations that deciphers health data with clinician-like logic. It indexes structured and unstructured data and replaces the complexity of querying with the simplicity of chatting.
Headquartered in South San Francisco, Jungla is a biotechnology company delivering robust and scalable results for clinical genetic and genomic testing. To achieve this, Jungla develops and combines advances in functional genomics, computational biophysics, and computer science to proactively inform on the risk of variants in our genome. Jungla aims to empower clinical genetic testing with quantitative, model-driven guidance to complement and enhance observational data. Whereas existing solutions routinely used in the market have demonstrably poor accuracies, Jungla delivers robust, scalable, and auditable support with dramatically higher accuracies and increasingly mechanistic cellular and biophysical insights. We are supported by leading technology and healthcare investors.
Twenty five percent of the world’s arable land is currently unusable due salt groundwater contamination and more arid environments. Endura Bio is engineering salt and drought tolerant plants to be more salt and drought tolerant to increase yields from marginal lands globally, unlocking the potential to feed the world.
Joywell Foods is developing the first healthy, protein sweeteners. Derived from exotic plants, protein sweeteners are rare compounds that provide an amazing taste without the calories. These proteins, produced through fermentation, have no glycemic impact and do not affect the gut microbiome. The company has received regulatory approvals, including FDA "no questions" letters and GRAS status for multiple proteins
Amino Labs is a biotechnology company that aims to make genetic engineering accessible to everyone. It works to enable the next industrial revolution of personalized manufacturing using biology and help solve the world's biggest problem from fuel to food to medicine. Driven by ground-breaking technology and UX, Amino Labs' easy-to-use kits are giving rise to the next 99 million bioengineers, from the ages of 8 and up. The company was founded in 2015 and is based in Lethbridge, Canada.
UPSIDE Foods (formerly known as Memphis Meats) develops meat produced directly from animal cells without the need to raise and slaughter actual animals. This approach requires significantly less water, land, and energy than conventional meat production, enabling consumers to enjoy meat that is clean, humane, and free of harmful chemicals. Co-founded and led by Dr. Uma Valeti in 2015, UPSIDE Foods is headquartered in Berkeley, California.
There is a tangled mess of wires, electrode stickers and blood pressure cuffs in the ICUs, ERs and operating rooms of modern medical facilities. The design of these instruments presents many challenges which include patient safety and comfort, measurement accuracy and reliability, equipment sterilization or disposability, burdensome ancillary staff requirements, and most importantly delays in care during critical diagnostic and resuscitative efforts. V-Sense Medical Devices use NASA radar technology to monitor vital signs without any contact with the patient. It does not require wearables, leads, contacts, stickers, or wires. Please sign up to our newsletter to stay in touch, and check our news and blog pages!
Zymochem provides a carbon-efficient bio-manufacturing platform that converts renewable feedstocks into bio-based materials without compromising price, performance, scale, or sustainability while minimizing CO2 loss during production. It also accelerates a real-zero economy by relieving carbon emissions in product development, use, and end-of-life.
Making the next generation of performance BioFabrics.
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