JDRF T1D Fund

Zucara Therapeutics Inc. is a biotechnology company focused on developing innovative therapeutics to prevent hypoglycemia, or low blood sugar, in patients with diabetes. Established in 2014 and headquartered in Toronto, Canada, with an additional office in Vancouver, Zucara is pioneering a once-daily treatment that aims to regulate the hormone somatostatin in the pancreas. This treatment specifically targets somatostatin type 2 receptors, which are not effectively controlled in patients with Type 1 diabetes. Zucara's approach presents a significant advancement in diabetes care by functioning as a preventative measure against hypoglycemia, contrasting with existing therapies that only provide rescue during acute episodes. Through its pre-clinical technology, Zucara Therapeutics aims to restore natural glucose levels in the blood, ultimately enhancing the quality of life for individuals living with diabetes.

Aspect Biosystems Ltd. is a biotechnology company based in Vancouver, Canada, specializing in 3D bioprinting and tissue engineering. Founded in 2013, the company leverages proprietary microfluidic 3D bioprinting technology to develop bioprinted tissue therapeutics aimed at transforming disease treatment. By integrating therapeutic cells and materials science, Aspect Biosystems creates allogeneic cell-based tissue therapeutics that can replace or repair damaged organ functions. The company also provides a Lab-on-a-printer technology that allows precise control over biomaterial composition and structure during tissue fabrication. Its innovative platform supports the development of novel therapeutics and enhances understanding in fundamental biology and disease research, catering to pharmaceutical firms and academic institutions focused on respiratory diseases and regenerative medicine. Aspect Biosystems is actively collaborating with researchers and industry leaders to address significant challenges in the field of regenerative medicine.