Main Sequence Ventures

Main Sequence Ventures, established in 2017 and based in Eveleigh, Australia, is a venture capital firm that invests in early-stage companies developing deep tech or frontier technologies to address global challenges. The firm backs ambitious founders creating the next set of global industries, with investments supported by the Australian National Science Agency, CSIRO, the Australian Federal Government, and private investors. Main Sequence leverages world-class research from Australian public research organizations, including CSIRO and universities, to identify and nurture promising startups.

Alezeia Brown

Investment Manager

Danielle Haj Moussa

Associate

Gabrielle Munzer

Partner

Mike Nicholls

Partner

Jun Qu

Investment Manager

Alejandra Romero

Associate

Past deals in Autonomous Vehicles

Arkeus

Venture Round in 2025
Arkeus is a technology company that specializes in the rapid development of autonomous optical systems for various surveillance and reconnaissance missions. These systems, optimized for surface sensors, aircraft, and drones, are designed to expedite decision-making in challenging environments, supporting applications such as intelligence gathering, border protection, force protection, and search and rescue across land, sea, and space.

Breaker

Pre Seed Round in 2025
Breaker develops cutting-edge software that transforms the interaction between humans and machines. Our platform leverages advanced decision-making, natural language communication, and enhanced perception to enable sophisticated autonomous capabilities in machines previously only achievable with human oversight. Designed for diverse industries, Breakers’ software facilitates a new level of efficiency and versatility in uncrewed systems, promising to revolutionize the way autonomous assets operate and collaborate with humans. Our mission is to make intelligent, autonomous collaboration a reality, bridging the gap between human intuition and machine precision.

Arkeus

Seed Round in 2023
Arkeus is a technology company that specializes in the rapid development of autonomous optical systems for various surveillance and reconnaissance missions. These systems, optimized for surface sensors, aircraft, and drones, are designed to expedite decision-making in challenging environments, supporting applications such as intelligence gathering, border protection, force protection, and search and rescue across land, sea, and space.

Advanced Navigation

Series B in 2022
Advanced Navigation, established in 2012 and based in Sydney, Australia, specializes in developing and manufacturing high-quality navigational technologies and robotics. The company's portfolio includes acoustic underwater navigation systems, GNSS/INS devices, MEMS AHRS, logging and post-processing units, satellite compasses, speed sensors, subsea antennas, and INS. With a background in mission-critical robotics and expertise spanning sensors, GNSS, inertial navigation, RF technologies, acoustics, robotics, AI, and algorithms, Advanced Navigation's products are designed to operate accurately under challenging conditions, serving clients in manufacturing and warehousing facilities to enhance process optimization and productivity.

Emesent

Series A in 2022
Emesent is a technology company focused on automating the collection and analysis of critical data in challenging underground environments. Its flagship product, Hovermap, is a LiDAR-mapping and autonomy payload designed for industrial drones, enabling them to operate and map in GPS-denied areas such as underground mines. Through Hovermap and other innovative solutions, Emesent enhances efficiency, safety, and operational insights for clients in sectors like mining and infrastructure. The company's team of experienced roboticists and engineers is dedicated to advancing drone autonomy and data analytics for various industrial applications, making Emesent a leader in its field.

Baraja

Series B in 2021
Baraja is a technology company that specializes in advanced LiDAR systems for autonomous vehicles. It has developed a unique platform called Spectrum-Scan™, which revolutionizes traditional LiDAR by utilizing a prism to refract light instead of relying on fragile moving parts. This innovative approach enables Baraja's technology to achieve exceptional range, precision, and reliability, even in challenging environments. By connecting a wavelength-tunable laser to prism-like optics via robust optical fiber, Baraja's system allows autonomous vehicles to instantly scan their surroundings from multiple angles with high detail and adaptability.

Advanced Navigation

Series A in 2019
Advanced Navigation, established in 2012 and based in Sydney, Australia, specializes in developing and manufacturing high-quality navigational technologies and robotics. The company's portfolio includes acoustic underwater navigation systems, GNSS/INS devices, MEMS AHRS, logging and post-processing units, satellite compasses, speed sensors, subsea antennas, and INS. With a background in mission-critical robotics and expertise spanning sensors, GNSS, inertial navigation, RF technologies, acoustics, robotics, AI, and algorithms, Advanced Navigation's products are designed to operate accurately under challenging conditions, serving clients in manufacturing and warehousing facilities to enhance process optimization and productivity.

Baraja

Series A in 2019
Baraja is a technology company that specializes in advanced LiDAR systems for autonomous vehicles. It has developed a unique platform called Spectrum-Scan™, which revolutionizes traditional LiDAR by utilizing a prism to refract light instead of relying on fragile moving parts. This innovative approach enables Baraja's technology to achieve exceptional range, precision, and reliability, even in challenging environments. By connecting a wavelength-tunable laser to prism-like optics via robust optical fiber, Baraja's system allows autonomous vehicles to instantly scan their surroundings from multiple angles with high detail and adaptability.

Emesent

Seed Round in 2018
Emesent is a technology company focused on automating the collection and analysis of critical data in challenging underground environments. Its flagship product, Hovermap, is a LiDAR-mapping and autonomy payload designed for industrial drones, enabling them to operate and map in GPS-denied areas such as underground mines. Through Hovermap and other innovative solutions, Emesent enhances efficiency, safety, and operational insights for clients in sectors like mining and infrastructure. The company's team of experienced roboticists and engineers is dedicated to advancing drone autonomy and data analytics for various industrial applications, making Emesent a leader in its field.
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