Massachusetts Life Sciences Center

The Massachusetts Life Sciences Center (MLSC) is a quasi-public agency dedicated to fostering innovation within the life sciences sector in Massachusetts. Established under the Massachusetts Life Sciences Act, the Center's mission is to create jobs and enhance scientific research that benefits public health. It provides financial support to both public and private entities engaged in life sciences research, development, and commercialization, focusing on areas such as biopharma, medical devices, diagnostics, and digital health. The MLSC operates an Accelerator Loan Program aimed at offering working capital to early-stage life sciences companies with strong potential for growth and technology commercialization. Through these initiatives, the Center aims to strengthen the ties within the Massachusetts life sciences community and promote economic development driven by innovation.

Mike Kennealy

Co-Chairman

Past deals in Boston, MA

Beth Israel Deaconess Medical Center is a prominent academic medical center located in Boston, Massachusetts, and serves as a major teaching hospital for Harvard Medical School. It offers a wide range of adult healthcare services, including specialized care in oncology, cardiology, gastrointestinal disorders, and spine health. The center is also known for its transplant services and comprehensive nursing care. In addition to patient care, Beth Israel Deaconess is deeply involved in biomedical research, focusing on areas such as vascular and transplantation studies, cancer signal transduction, and molecular imaging. The institution supports medical education through training programs for students, interns, and residents, fostering a new generation of healthcare professionals. With nearly three-quarters of a million patient visits annually, it is a key player in Boston's medical landscape and has a longstanding commitment to community service and research excellence.
Brigham and Women's Hospital (BWH) is a prominent medical institution located in Boston, Massachusetts, and serves as the largest hospital within the Longwood Medical and Academic Area. It is the second largest teaching affiliate of Harvard Medical School, featuring 793 beds. BWH, in partnership with Massachusetts General Hospital, is a founding member of Partners HealthCare, the largest healthcare provider in the state. The hospital is renowned for its comprehensive patient care, biomedical research, and educational programs, especially in fields such as heart and vascular care, cancer treatment, neurology, orthopedics, and women's health. BWH is also the second largest recipient of National Institutes of Health funding in the country, contributing to significant medical advancements, including organ transplantation. The hospital offers a wide array of outpatient services and operates a network of clinics and primary care health centers, ensuring accessible healthcare not only locally but also through global initiatives in 120 countries. Additionally, BWH is dedicated to promoting health equity and addressing healthcare disparities.

New Balance

Grant in 2020
New Balance, their job is to aid athletes in their pursuit of excellence, whether that means helping professional athletes set records and win medals, or propelling everyday athletes to achieve a new PR, run their first 5K or just to live a more healthy and active lifestyle. Their products are the perfect blend of function and fashion, giving you the performance technology you need and the style you want. Their associates around the world bring these goals to life with their high-level skills and creativity. While they offer the best product on the market, they’re also equally committed to giving back. So while they look to succeed, they believe in ensuring others have the same opportunity.
Boston Children's Hospital provides pediatric health care services. The hospital provides surgical, radiological examination, and clinical and cancer research services. Additionally, it offers diabetes, endocrinology, gastroenterology, urology, neonatology, orthopedics, and pulmonology healthcare services. The hospital also provides community service programs and postdoctoral training services. Boston Children's Hospital was founded in 1869 and is based in Boston, Massachusetts. Boston Children's Hospital operates as a subsidiary of Children's Medical Center Corporation.
Brigham and Women's Hospital (BWH) is a prominent medical institution located in Boston, Massachusetts, and serves as the largest hospital within the Longwood Medical and Academic Area. It is the second largest teaching affiliate of Harvard Medical School, featuring 793 beds. BWH, in partnership with Massachusetts General Hospital, is a founding member of Partners HealthCare, the largest healthcare provider in the state. The hospital is renowned for its comprehensive patient care, biomedical research, and educational programs, especially in fields such as heart and vascular care, cancer treatment, neurology, orthopedics, and women's health. BWH is also the second largest recipient of National Institutes of Health funding in the country, contributing to significant medical advancements, including organ transplantation. The hospital offers a wide array of outpatient services and operates a network of clinics and primary care health centers, ensuring accessible healthcare not only locally but also through global initiatives in 120 countries. Additionally, BWH is dedicated to promoting health equity and addressing healthcare disparities.
Northeastern University, established in 1898 and based in Boston, Massachusetts, is a non-profit institution that offers a wide array of undergraduate and graduate programs across nine colleges and schools. The university emphasizes experiential learning, integrating rigorous academic coursework with practical experience through its Cooperative Education Program. This unique approach allows students, particularly in the legal field at the Northeastern University School of Law, to alternate between traditional studies and full-time work placements in legal settings, enhancing their skills and professional networks. Northeastern's mission is to equip students with the knowledge, ethical values, and practical skills needed to serve clients and the public effectively. The university also maintains graduate campuses in Charlotte, North Carolina, and Seattle, further expanding its educational reach.
Harvard Medical School, established in 1782, is dedicated to advancing human health through education, research, and clinical practice. The institution fosters a diverse community and has produced numerous leaders in science and medicine who are making significant contributions worldwide. Since the early 1800s, faculty members have been at the forefront of medical innovation, achieving notable milestones such as the introduction of the smallpox vaccine to the United States. Harvard Medical School's faculty includes over 11,000 individuals, many of whom have received international recognition, including nine Nobel Prizes for groundbreaking research. The school’s main campus in Boston houses 146 tenured faculty members and serves as a hub for medical education, while its extensive network of affiliations with 16 prestigious hospitals and research institutes enhances clinical training and care. This collective expertise and commitment to problem-solving enable Harvard Medical School to lead advancements in medical education and research, ultimately benefiting communities on local, national, and global levels.

Mytide Therapeutics

Grant in 2019
Mytide is committed to providing peptides to serve a diverse array of applications. During their beta phase, they intend to work closely with partners to overcome challenges in synthesizing and purifying particular classes of peptides of interest, identify useful peptide modifications, and design and construct peptide libraries. We provide initial partners access to their cloud platform for immediate ordering, properties calculator, order tracking, and interactive data display with guaranteed purities of >90%, 3 mg quantities, and 5-day turnaround of peptides up to length 40 AA.

Gel4Med

Grant in 2019
Gel4Med LLC is a Boston-based medical technology company founded in 2015, specializing in the development of innovative biomaterials for tissue treatment and regeneration. The company focuses on creating an antimicrobial tissue-scaffolding matrix designed to eliminate antibiotic-resistant bacteria while promoting tissue regeneration. Its platform employs bioinspired engineering approaches to address healthcare challenges, particularly in wound care and tissue regeneration. The core technology features self-assembling peptides that function as an antibacterial barrier and enhance healing, enabling patients to prevent infections during surgical procedures. Through its advancements in regenerative medicine, Gel4Med aims to improve patient outcomes significantly.

XGenomes

Grant in 2019
XGenomes LLC develops technology to read DNA sequence information. The company's technology works by unzipping strands of DNA and sequencing them concurrently. Its DNA sequencing technology serves clinical research and development, industrial biotechnology, and ancestry industry. The company was incorporated in 2018 and is based in Boston, Massachusetts.

UrSure

Grant in 2019
UrSure, Inc. is a Boston-based company that develops and commercializes diagnostic urine tests designed to measure adherence to HIV medications, including pre-exposure prophylaxis (PrEP). Founded in 2015, UrSure focuses on creating patient-friendly diagnostic tests aimed at improving medication adherence. The company offers both urine and blood test kits specifically for assessing adherence to HIV treatment regimens. Through its innovative diagnostic solutions, UrSure addresses a critical need in managing HIV care and prevention.

Flaskworks

Grant in 2019
Flaskworks specializes in the development of immunotherapeutics, particularly focusing on dendritic cell-based vaccines aimed at treating cancer and other diseases. The company has created innovative technology to manufacture dendritic cells and has designed modular, closed, and disposable systems that help eliminate bottlenecks in therapy production. This advancement enables physicians to provide more effective treatments to patients, enhancing the overall success of immunotherapy.

PhagePro

Grant in 2019
PhagePro is an early-stage biotechnology therapeutics company that develops bacteriophage-based products to help the world's most vulnerable communities.
University of Massachusetts Lowell is a high-ranking university, with several nationally recognized academic departments. Located about 30 minutes from Boston in Lowell, Massachusetts, UMass Lowell offers more than 100 degree programs at the undergraduate and graduate levels. UMass Lowell has several nationally recognized, research-oriented programs, including science and engineering. These programs undertake groundbreaking research and also provide exceptional work opportunities for its students and graduates. Other programs at UMass Lowell include liberal and fine arts, humanities, health-related programs, teacher education and social sciences. UMass Lowell also offers a range of internship opportunities for students who wish to gain experience in their field of study. Student life options at UMass Lowell include more than 100 diverse student organizations, leadership programs and community service opportunities. Lowell’s admissions policies are moderately competitive. Financial aid is available to eligible students through loans, academic scholarships and other sources to help cover tuition.
Boston University School of Medicine is one of the graduate schools of Boston University. It holds the unique distinction as the first institution in the world to formally educate female physicians. Boston University School of Medicine offers MA, MS, and PhD degrees through its Division of Graduate Medical Sciences (GMS). GMS offers MA degrees in bioimaging, clinical investigation, medical sciences, mental health counseling, and behavioral medicine. MS degrees are available in biomedical forensics, forensic anthropology, and genetic counseling. GMS also grants MD and PhD degrees in areas such as anatomy and neurobiology, biomedical neuroscience, genetics and genomics, microbiology, pathology and laboratory medicine, behavioral neuroscience, biophysics, immunology, molecular medicine, pharmacology, biochemistry, cell and molecular biology, medical nutrition sciences, oral biology, and physiology. Originally known as the New England Female Medical College, the university was subsequently renamed Boston University School of Medicine in 1873. It is notably also the first medical school in the United States to award an M.D. degree to an African-American woman in 1864. As the only medical school located in the South End neighborhood of Boston, Massachusetts, Boston University School of Medicine and Boston Medical Center, its primary teaching hospital, operates the largest 24-hour Level I trauma center in New England, the largest network of regional community health centers, and possesses the most diverse patient base in New England. Boston University School of Medicine is also the home of the world-renowned Framingham Heart Study, from which all knowledge of cardiovascular disease risk factors were originally discovered. Notable alumni of the medical school include Marcia Angell, former editor-in-chief of the prestigious New England Journal of Medicine and the only woman to hold the position in the journal's almost 200 year history, as well as Louis Wade Sullivan, former Secretary of the U.S. Department of Health and Human Services and founder of Morehouse School of Medicine. Boston University School of Medicine is ranked 30th on the 2014 list of Best Medical Schools by the U.S. News and World Report. Boston University School of Medicine was founded in 1848 and is based in Boston, Massachusetts, United States.
Boston Children's Hospital provides pediatric health care services. The hospital provides surgical, radiological examination, and clinical and cancer research services. Additionally, it offers diabetes, endocrinology, gastroenterology, urology, neonatology, orthopedics, and pulmonology healthcare services. The hospital also provides community service programs and postdoctoral training services. Boston Children's Hospital was founded in 1869 and is based in Boston, Massachusetts. Boston Children's Hospital operates as a subsidiary of Children's Medical Center Corporation.
Massachusetts General Hospital, established in 1811, is an independent non-profit private foundation located in Boston, Massachusetts. It was founded with the mission to provide care to the sick, regardless of their socioeconomic status. As the first teaching hospital for Harvard University’s medical school, it has consistently redefined excellence in healthcare through a commitment to collaboration, innovation, and education. The hospital prioritizes the well-being of its patients, striving to deliver safe and compassionate care while advancing medical research and education. With a focus on serving diverse communities, Massachusetts General Hospital emphasizes the importance of inclusion and equity in its practices, ensuring that it meets the needs of all individuals it serves.
Brigham and Women's Hospital (BWH) is a prominent medical institution located in Boston, Massachusetts, and serves as the largest hospital within the Longwood Medical and Academic Area. It is the second largest teaching affiliate of Harvard Medical School, featuring 793 beds. BWH, in partnership with Massachusetts General Hospital, is a founding member of Partners HealthCare, the largest healthcare provider in the state. The hospital is renowned for its comprehensive patient care, biomedical research, and educational programs, especially in fields such as heart and vascular care, cancer treatment, neurology, orthopedics, and women's health. BWH is also the second largest recipient of National Institutes of Health funding in the country, contributing to significant medical advancements, including organ transplantation. The hospital offers a wide array of outpatient services and operates a network of clinics and primary care health centers, ensuring accessible healthcare not only locally but also through global initiatives in 120 countries. Additionally, BWH is dedicated to promoting health equity and addressing healthcare disparities.
Northeastern University, established in 1898 and based in Boston, Massachusetts, is a non-profit institution that offers a wide array of undergraduate and graduate programs across nine colleges and schools. The university emphasizes experiential learning, integrating rigorous academic coursework with practical experience through its Cooperative Education Program. This unique approach allows students, particularly in the legal field at the Northeastern University School of Law, to alternate between traditional studies and full-time work placements in legal settings, enhancing their skills and professional networks. Northeastern's mission is to equip students with the knowledge, ethical values, and practical skills needed to serve clients and the public effectively. The university also maintains graduate campuses in Charlotte, North Carolina, and Seattle, further expanding its educational reach.

Year Up

Grant in 2018
Year Up's mission is to close the Opportunity Divide by providing urban young adults with the skills, experience, and support that will empower them to reach their potential through professional careers and higher education.

Insightfil

Grant in 2017
Insightfil focuses on enhancing patient outcomes by addressing medication errors and improving adherence rates. The company offers a medication adherence platform that automates the dispensing of pills based on doctors' prescriptions and includes a reminder system to ensure patients take their medications as directed. By striving to increase medication adherence from the typical rate of 40% to the National Institutes of Health goal of 75%, Insightfil aims to optimize healthcare professionals' time and reduce the costs and risks associated with medication administration. Their innovative "Personalized Wellness Portfolio" connects patients, clinics, and pill manufacturers, marking it as a pioneering solution in therapy administration.

Artaic

Grant in 2017
Artaic, LLC, established in 2007 and based in Boston, Massachusetts, specializes in designing and fabricating custom tile work for both commercial and residential markets. The company offers a wide range of mosaic and tile designs suitable for various applications including bathrooms, backsplashes, flooring, hotels, kitchens, lobbies, outdoor spaces, pools, and restaurants. In addition to its design services, Artaic provides installation services to clients. The company employs advanced technology, utilizing computer-aided design software, a cloud-based logistics system, and an innovative robotic mosaic assembly system to ensure precision and efficiency in its projects. Artaic has garnered support through investments from angel investors and corporate offices, as well as significant non-dilutive grant funding from various organizations.

Aldatu Biosciences

Grant in 2017
Aldatu Biosciences Inc. is a biotechnology company based in Cambridge, Massachusetts, that specializes in developing diagnostic tools to address drug resistance in antiretroviral treatments for HIV. Utilizing its proprietary PANDAA platform, which stands for pan degenerate amplification and adaptation, the company provides advanced genotyping solutions that help healthcare providers tailor HIV treatments to individual patients. This approach aims to enhance patient outcomes while also reducing the overall costs associated with HIV care. Founded in 2014, Aldatu is focused on tackling diagnostic challenges in global health, particularly in infectious diseases, and is dedicated to improving the quality of patient care and healthcare efficiency.

Aldatu Biosciences

Grant in 2017
Aldatu Biosciences Inc. is a biotechnology company based in Cambridge, Massachusetts, that specializes in developing diagnostic tools to address drug resistance in antiretroviral treatments for HIV. Utilizing its proprietary PANDAA platform, which stands for pan degenerate amplification and adaptation, the company provides advanced genotyping solutions that help healthcare providers tailor HIV treatments to individual patients. This approach aims to enhance patient outcomes while also reducing the overall costs associated with HIV care. Founded in 2014, Aldatu is focused on tackling diagnostic challenges in global health, particularly in infectious diseases, and is dedicated to improving the quality of patient care and healthcare efficiency.
Full Investment Portfolio: U.S. Government Money Market Fund - 0.67% U.S. Government Securities - 7.01% U.S. Equity Securities - 6.58% U.S. Equity Mutual Funds - 12.01% International Equity Securities - 3.07% International Equity Mutual Funds - 19.89% Alternative Investments - 50.77% Founded in 1947, the Dana-Farber Cancer Institute, Inc. is a non-profit organisation based in the United States. The foundation provides cancer treatment to adults and children.
Harvard Medical School, established in 1782, is dedicated to advancing human health through education, research, and clinical practice. The institution fosters a diverse community and has produced numerous leaders in science and medicine who are making significant contributions worldwide. Since the early 1800s, faculty members have been at the forefront of medical innovation, achieving notable milestones such as the introduction of the smallpox vaccine to the United States. Harvard Medical School's faculty includes over 11,000 individuals, many of whom have received international recognition, including nine Nobel Prizes for groundbreaking research. The school’s main campus in Boston houses 146 tenured faculty members and serves as a hub for medical education, while its extensive network of affiliations with 16 prestigious hospitals and research institutes enhances clinical training and care. This collective expertise and commitment to problem-solving enable Harvard Medical School to lead advancements in medical education and research, ultimately benefiting communities on local, national, and global levels.
University of Massachusetts Lowell is a high-ranking university, with several nationally recognized academic departments. Located about 30 minutes from Boston in Lowell, Massachusetts, UMass Lowell offers more than 100 degree programs at the undergraduate and graduate levels. UMass Lowell has several nationally recognized, research-oriented programs, including science and engineering. These programs undertake groundbreaking research and also provide exceptional work opportunities for its students and graduates. Other programs at UMass Lowell include liberal and fine arts, humanities, health-related programs, teacher education and social sciences. UMass Lowell also offers a range of internship opportunities for students who wish to gain experience in their field of study. Student life options at UMass Lowell include more than 100 diverse student organizations, leadership programs and community service opportunities. Lowell’s admissions policies are moderately competitive. Financial aid is available to eligible students through loans, academic scholarships and other sources to help cover tuition.
East Boston High School is a public high school located in the neighborhood of East Boston in Boston, Massachusetts, United States.
Boston Educational Development Foundation helps to build a fundraising and program operations capacity for public schools in Boston.

Snowden International

Grant in 2017
Snowden International School is a multicultural, multilingual urban high school in the center of Copley Square, Boston. Snowden International is a college preparatory high school with international studies and a world language focus that offers a rigorous academic curriculum.

Artaic

Grant in 2016
Artaic, LLC, established in 2007 and based in Boston, Massachusetts, specializes in designing and fabricating custom tile work for both commercial and residential markets. The company offers a wide range of mosaic and tile designs suitable for various applications including bathrooms, backsplashes, flooring, hotels, kitchens, lobbies, outdoor spaces, pools, and restaurants. In addition to its design services, Artaic provides installation services to clients. The company employs advanced technology, utilizing computer-aided design software, a cloud-based logistics system, and an innovative robotic mosaic assembly system to ensure precision and efficiency in its projects. Artaic has garnered support through investments from angel investors and corporate offices, as well as significant non-dilutive grant funding from various organizations.

Insightfil

Grant in 2016
Insightfil focuses on enhancing patient outcomes by addressing medication errors and improving adherence rates. The company offers a medication adherence platform that automates the dispensing of pills based on doctors' prescriptions and includes a reminder system to ensure patients take their medications as directed. By striving to increase medication adherence from the typical rate of 40% to the National Institutes of Health goal of 75%, Insightfil aims to optimize healthcare professionals' time and reduce the costs and risks associated with medication administration. Their innovative "Personalized Wellness Portfolio" connects patients, clinics, and pill manufacturers, marking it as a pioneering solution in therapy administration.

Akili Interactive

Grant in 2015
Akili Interactive Labs, Inc. is a digital medicine company based in Boston, Massachusetts, that develops innovative platform technology to enhance cognitive abilities through video game-like experiences. Incorporated in 2011, the company focuses on creating clinically validated cognitive therapeutics, assessments, and diagnostics that can be prescribed and monitored by physicians remotely. Akili's cognitive engine supports multiple clinical game versions designed for patient engagement and remote data capture. Its proprietary adaptive mechanics allow the software to personalize to each patient's ability level automatically, without requiring clinician input. This approach aims to provide a cost-effective alternative to traditional medical treatments, making advanced cognitive therapies accessible to patients regardless of their location.

Agile Devices

Grant in 2015
Agile Devices offer catheter-based interventional procedures helping patients during a stroke. It helps medical practitioners reduce the procedure time to respond to time bound emergencies.

Artaic

Grant in 2015
Artaic, LLC, established in 2007 and based in Boston, Massachusetts, specializes in designing and fabricating custom tile work for both commercial and residential markets. The company offers a wide range of mosaic and tile designs suitable for various applications including bathrooms, backsplashes, flooring, hotels, kitchens, lobbies, outdoor spaces, pools, and restaurants. In addition to its design services, Artaic provides installation services to clients. The company employs advanced technology, utilizing computer-aided design software, a cloud-based logistics system, and an innovative robotic mosaic assembly system to ensure precision and efficiency in its projects. Artaic has garnered support through investments from angel investors and corporate offices, as well as significant non-dilutive grant funding from various organizations.

Insightfil

Grant in 2015
Insightfil focuses on enhancing patient outcomes by addressing medication errors and improving adherence rates. The company offers a medication adherence platform that automates the dispensing of pills based on doctors' prescriptions and includes a reminder system to ensure patients take their medications as directed. By striving to increase medication adherence from the typical rate of 40% to the National Institutes of Health goal of 75%, Insightfil aims to optimize healthcare professionals' time and reduce the costs and risks associated with medication administration. Their innovative "Personalized Wellness Portfolio" connects patients, clinics, and pill manufacturers, marking it as a pioneering solution in therapy administration.

Vaxess Technologies

Debt Financing in 2013
Vaxess Technologies, Inc. is a biotechnology company based in Boston, Massachusetts, founded in 2011. It specializes in developing and commercializing silk biomaterial technologies aimed at improving vaccine delivery and storage. The company has created the MIMIX microneedle platform, which facilitates transdermal delivery of vaccines and therapies, and the MATRIX formulation and drying platform, which enhances the stability of vaccines, therapeutics, and diagnostic products. By utilizing a silk-derived protein, Vaxess enables vaccines to be stored and transported without refrigeration, thereby reducing distribution costs and increasing access to essential healthcare products globally.

Sample6

Debt Financing in 2012
Sample6 is a biotechnology company that specializes in the development of a synthetic-biology based diagnostic system for bacteria. Its innovative technology enables enrichment-free detection of harmful bacteria, identifying levels as low as 1 CFU/ml within just four hours. The proprietary Bioillumination Platform, created by a team of researchers including Professor Tim Lu from MIT, allows for the engineering of bioparticles that target specific unwanted bacteria, illuminating them for detection. This system is coupled with sensitive sensor technology that provides rapid on-site results without the need for a laboratory. Sample6 aims to enhance public health and safety by enabling quick and efficient detection of harmful bacteria across various industries, including food production, retail, and healthcare, addressing environments where humans and bacteria interact.
Full Investment Portfolio: U.S. Government Money Market Fund - 0.67% U.S. Government Securities - 7.01% U.S. Equity Securities - 6.58% U.S. Equity Mutual Funds - 12.01% International Equity Securities - 3.07% International Equity Mutual Funds - 19.89% Alternative Investments - 50.77% Founded in 1947, the Dana-Farber Cancer Institute, Inc. is a non-profit organisation based in the United States. The foundation provides cancer treatment to adults and children.

Joslin Diabetes Center

Debt Financing in 2012
Joslin Diabetes Center, a teaching and research affiliate of Harvard Medical School, is a one-of-a-kind institution on the front lines of the world epidemic of diabetes — leading the battle to conquer diabetes in all of its forms through cutting-edge research and innovative approaches to clinical care and education.

Immunetics

Grant in 2011
Immunetics, Inc. is a biotechnology company based in Boston, Massachusetts, that develops and markets immunoassay and molecular probe technology solutions for the diagnosis of infectious diseases. Founded in 1987, the company offers a range of diagnostic assays, including the C6 B.burgdorferi ELISA Kit for Lyme disease, the QuickELISA Anthrax-PA Kit for anthrax antibody detection, and the BacTx Test for bacterial contamination in platelets. Immunetics also produces the Miniblotter instrument system for various assay applications and the QualiCode western blot assays for challenging diagnoses. The company sells its products through distributors in multiple countries, including those in Europe, North America, and Asia. Immunetics has issued patents for its tests and is actively developing new assays for diseases such as Babesiosis and Chagas disease, which pose emerging risks to the blood supply.
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