MassChallenge

CloEE is an AI-driven digital advisor for discrete manufacturers. It enhances sustainability by improving Overall Equipment Efficiency (OEE), reducing energy consumption by 30%, and minimizing emergency stops by 95%. CloEE leverages generative AI to deliver continuous improvement using real-time data from manufacturing equipment, MES, and ERP systems. It empowers manufacturers to tackle production downtime, delivery delays, low OEE, high defect rates, and excessive energy costs.

Fili Pari is a company specializing in the design of mineral-based clothing, aiming to redefine traditional fashion concepts. The company produces women's apparel using enhanced marble powders, which are integrated into a wearable membrane containing marble dust. This innovative material provides consumers with garments that are waterproof, breathable, windproof, and flame-retardant, offering an alternative to conventional clothing products. Fili Pari focuses on combining innovation, quality, and sustainability in its offerings.

EcoAct Tanzania is a manufacturer of eco-friendly building materials that recycles post-consumer plastic waste, packaging materials, and agricultural waste into durable plastic lumber. Using chemical-free extrusion and energy-conscious processes, the company creates timber substitutes that resist rot and termites and offer an affordable alternative to wood for construction and outdoor applications.

Xibus Systems develops and markets innovative microbiological analytics tools. These tools test consumable solutions for pathogens, allergens, and spoilage organisms in the food and beverage industry. The company is headquartered in Somerville, Massachusetts.

Seprify develops and sells cellulose-based white pigments and opacifiers, aiming to replace titanium dioxide in various industries. Their plant-derived solutions are renewable, biocompatible, and scalable, promoting sustainability and safety in product manufacturing.

Tree for the The goal is to increase the electric guitar's accessibility while concurrently shifting the source of its materials from an extractive, colonialist origin to a sustainable one.

FluxWorks specializes in the development and manufacturing of magnetic gears and integrated motors. Their products offer superior powertrain solutions, characterized by low weight, reliability, lubrication-free operation, and minimal maintenance costs.

AC3D is a US-based company developing vertically integrated 3D printing technology for the construction industry. Its mission is to address global housing needs, waste reduction, and climate change through automated additive manufacturing. By providing comprehensive solutions including printers, materials, software, and house designs, AC3D aims to make construction cheaper, greener, and more productive.

3D Architech specializes in innovative metal manufacturing solutions using proprietary low-cost 3D printing technology. This enables enhanced design flexibility, improved sustainability, and increased versatility in metal component production.

Crimagno is a manufacturer of high-end hybrid design and sports shoes for men and women, focusing on sustainability through the use of eco-friendly materials. The company aims to create stylish and gender-neutral footwear by combining expertise in industrial design with responsible production practices. Crimagno's commitment to sustainability ensures that its products are environmentally friendly, appealing to customers who prioritize ecological considerations in their purchasing decisions.

Seprify develops and sells cellulose-based white pigments and opacifiers, aiming to replace titanium dioxide in various industries. Their plant-derived solutions are renewable, biocompatible, and scalable, promoting sustainability and safety in product manufacturing.

We founded AtomicAI to bring advances in computing and machine learning to nanomaterials manufacturing. We believe that nanomaterials will transform energy, electronics, and quantum technologies. But nanomaterials are really hard to make. We're here to help.

Wave Company specializes in innovative smart apparel designed to enhance human movement. Utilizing proprietary conductive silicone technology, Elecsil, the company creates advanced sportswear and smart wear that measure and improve recovery and performance. Wave Company also licenses its core material technology to various industries.

Advanced Microfluidics, based in Ecublens, Switzerland, is a machinery manufacturing company that specializes in developing and producing high-end lab equipment components. Their primary focus is on automated liquid handling systems, which are designed to minimize cross-contamination and reduce internal volume, ensuring precise and efficient fluidic performance. The company's products cater to both laboratory and industrial sectors, providing solutions with no dead volumes.

Founded in 2018, M Aerospace RTC is an aerospace company based in Austin, Texas. It specializes in large-scale metal 3D printing technology and services, offering a wide range of metal materials and the capacity to produce large pieces.

Refined Imaging is a technology company that develops and applies interferometry-based imaging solutions. Their core product is an advanced platform specializing in microfabrication, X-ray, and neutron grating interferometry, which generates detailed images by harnessing electromagnetic wave interactions. This platform enables industries to enhance the performance of gratings with support structures. Notably, Refined Imaging offers a unique cyber-physical trust anchor service that facilitates the authentication of additively manufactured parts and detection of counterfeit items. Their imaging process is repeatable, allowing for data comparison against blockchain records to provide definitive yes or no responses for authentication purposes.

Founded in 2016, LabsCubed specializes in manufacturing automated material testing systems. These systems are designed to efficiently load tensile samples and plastic materials for numerical simulation, aiding companies in creating innovative materials.

Founded in 2017 and headquartered in Boston, Southie Autonomy develops robot software that enables industrial robots to be repurposed and redeployed by users without specialized skills. Its system aims to reduce time, cost, and skill barriers for applications like kitting, palletizing, and simple assembly.

Femly is a Maryland-based producer of plant-based, environmentally friendly feminine hygiene products, including organic cotton tampons, pads, and cups. The company sells online and through a monthly subscription model, delivering to individual customers as well as restrooms in hotels, coworking facilities, and colleges. Founded in 2016, Femly emphasizes sustainable materials and easy access to menstrual care, offering convenient, health-conscious options that align with environmental values.

FLITE Material Sciences is a surface engineering company that specializes in the protection of industrial surfaces from rust, ice, and fouling through innovative patented laser techniques. By replacing toxic and temporary chemical coatings with environmentally friendly methods, FLITE enhances the safety and resilience of products. Its advanced techniques not only prevent corrosion and ice buildup but also improve the adhesion of lubricants and other treatments. This approach significantly reduces or eliminates the need for millions of liters of chemicals traditionally used in priming, painting, and cleaning processes, allowing clients to create durable surfaces without environmental impact or adhesion issues.

Endeavor Composites specializes in producing non-woven reinforcing fiber mats designed for advanced composites manufacturing. Utilizing both virgin and recycled fibers, the company's unique process enables zero waste solutions, ensuring defect-free, fully isotropic mats with consistent quality. This innovation caters primarily to the automotive industry, significantly reducing production waste and manufacturing costs.

Spiral Technology is a developer of an augmented reality platform aimed at enhancing the efficiency of factory workers during quality inspections. By leveraging Augmented Reality and Machine Learning, the company provides software solutions that facilitate the creation of accurate inspection records, thereby reducing error rates. The platform is designed to power mixed reality headsets, delivering essential intelligence directly to the workforce. This technology empowers field workers by integrating machine intelligence and computer vision, enabling them to concentrate on and identify issues that arise at the intersection of various systems. Through its innovative approach, Spiral Technology seeks to improve operational accuracy and efficiency in industrial settings.

Rotor X supplies aircraft components to defence contractors for advanced tactics. It involves the manufacturing of customised aircraft and helicopter kits. They support the existing helicopter owners around the world with parts and maintenance services. An online inquiry form is available on their websites.

RoadPrintz, Inc. is a manufacturer based in Cleveland Heights, Ohio, specializing in robotic equipment designed for comprehensive road painting and pavement markings. Incorporated in 2018, the company produces machines that survey, map, paint, and repaint road markings, including turn arrows and lane separators. RoadPrintz aims to enhance road safety by making effective visual street markings more affordable and accessible. Its robotic street painting systems enable traffic engineers and road painting contractors to efficiently specify and apply paint schemes on roads, thereby reducing the risk of accidents and improving overall road safety.

NanoFlowX is a manufacturer specializing in conformal coatings that provide advanced protection for electronic devices across various industries. The company has developed patented IP68 technology, which delivers exceptional waterproofing and dust resistance. Its coatings are applied through a streamlined two-step process that takes only two minutes, eliminating the need for masking and facilitating rework. This innovative approach allows manufacturers to produce weatherized devices more efficiently, resulting in faster turnaround times and reduced costs. NanoFlowX's partnerships with organizations such as IMSA WeatherTech and the Lucas Oil Off Road Regional series further underscore its commitment to providing versatile and reliable solutions in the electronics market.

Visense is a technology company focused on enhancing industrial production through a remote error monitoring and diagnosis solution. By utilizing sensor and camera equipment coupled with advanced data analytics and machine learning, Visense delivers real-time insights into production errors. This innovative approach enables users to identify and resolve incidents with remarkable speed and accuracy, cutting the time required for error diagnosis and resolution by 50%. Additionally, Visense's system supports improved machine planning and promotes error prevention, ultimately leading to enhanced production quality and increased machine availability.

Ottan is a startup dedicated to the circular economy. It upcycles food and agricultural waste into sustainable bio-composite materials, offering durable and aesthetically pleasing alternatives to wood, stone, or acrylic surfaces for industries such as cladding, furniture, and housewares.

Sayetech designs, manufactures, and services smart agricultural machinery tailored for African conditions. Their products enhance productivity and mechanization in smallholder farming, featuring durable equipment, embedded IoT devices, mobile app integration, and affordable access to modern tools.

Loo Works limited manufactures sustainable components from solid waste materials to create container based toilet in every home

Nautilus Defense specializes in the creation and manufacture of advanced textile and composite-integrated systems aimed at monitoring structural assets and their environments. The company develops integrated maritime surveillance systems and cospas-sarsat meosar global deployment solutions. Its offerings include strain-sensing yarns, antennas, wearable systems, deployable systems, device arrays, and micrometers. Nautilus Defense is committed to rapid experimental development, delivering innovative material-based capabilities that enhance the performance of textile-integrated systems for its clients.

IndustrialML is a Boston-based startup founded in 2018 by Arjun Chandar, AJ Perez, and Hunter Ashmore. The company specializes in developing enterprise software aimed at enhancing the efficiency of industrial operations. Its software solutions focus on maximizing uptime and minimizing scrap by collecting, cleaning, and curating data from factory sensors and enterprise IT systems. By integrating process monitoring with real-time analytics, IndustrialML provides actionable insights to operators and engineers, helping to keep production lines running smoothly. Through its innovative technology, the company supports industrial clients in making their factories smarter and more productive.

Elemental Coatings specializes in advanced anti-icing coatings designed to prevent ice buildup on various surfaces. Utilizing proprietary technology and unique materials properties, their coatings significantly reduce ice adhesion strength while maintaining durability and stability against chemicals and UV rays. Highly customizable, these coatings have applications across aerospace, automotive, trucking, power transmission, and consumer sectors where ice accumulation is a concern.

Kügar is an industrial automation company that offers robotic automation solutions. It specializes in the fields of industrial engineering, manufacturing, and robotics. It was founded in 2013 and headquartered in San Francisco, California.

Daika developed a formulation that enables digital fabrication of wood using existing mass manufacturing technologies. Daika offers a circular economy option for the industry as well as ground-breaking new applications for natural wood resources. These products preserve the distinctive features of wood, such as warmth, feel, and acoustics, and can be handled in the same manner as conventional wood.

Adapt fit manufactures magnetic sewn strips in the place of buttons and zippers to provide easy way of dressing to patients.

Founded in 2016, Asystom specializes in predictive maintenance solutions for industrial equipment. Their stand-alone system combines sensors and embedded intelligence to monitor all components, regardless of age or design, preventing breakdowns and minimizing downtime.

Applied Bioplastics is a company focused on providing sustainable alternatives to petroleum-based plastics. Its mission is to eliminate dependence on virgin plastics by offering affordable, high-grade recycled options that incorporate sustainably sourced plant materials from developing nations. This approach not only reduces costs but also addresses the economic barriers that hinder companies from adopting recycled plastics. The company's bioplastic products are designed to lower carbon dioxide emissions and minimize habitat destruction, combining plant fibers with standard, recycled, or biobased polymers. These materials can be injection molded or extruded, making them suitable for a wide range of applications across various industries, including household goods, automotive, appliances, electronics, and outdoor equipment, all while maintaining quality and performance.

SimpleJohn is a video instruction app for manufacturing companies that helps capture and distribute important operating procedures.

NALA Membranes develops reverse osmosis membranes that are chlorine-stable and chlorine-resistant, designed to enhance water purification efficiency while reducing waste, energy use, and operating costs. The membranes are durable and resistant to fouling and biofouling, enabling longer service life even in challenging industrial wastewater applications and allowing operation at lower pressures. By lowering energy consumption and greenhouse gas emissions, the technology supports more sustainable and cost-effective water treatment across industries.

Global Security Advancements helps the consumers and defense industry along with firearm manufacturers and retail companies. It develops, manufactures, and markets "TRA-SOR" the "World's First IoT Safe Storage System".

Ouli is a skincare manufacturing company s[ecializes in regenerating axolotl salamander and synthetic biology to extract.

Enzymit is a biotechnology company focused on revolutionizing global manufacturing through sustainable and efficient bio-production methods. It specializes in developing cell-free bio-production technology that aims to eliminate the inefficiencies and complexities associated with traditional bio-production. Enzymit employs artificial intelligence and deep learning algorithms to design novel enzymes, which serve as molecular machines capable of transforming abundant feedstocks into valuable products, including pharmaceuticals, cosmetics, food, and materials. The company’s small, modular bio-reactors facilitate this process, promoting resource independence while minimizing environmental impact. By moving away from conventional whole-cell methods to utilizing nature's elemental building blocks, Enzymit enhances cost-effectiveness, efficiency, and sustainability in bio-production, while also providing greater flexibility in product customization for various industries.

RobotAI develops advanced artificial intelligence software that enhances the capabilities of standard RGB cameras, transforming them into sophisticated 3D measurement devices. This innovative technology allows for the recognition of objects along with their positions and orientations from a single image, enabling a variety of automation tasks such as pick and place, palletizing, and bin picking. RobotAI's solution is distinguished by its speed, precision, and cost-effectiveness compared to alternative active vision systems. The company focuses on teaching robots to perceive objects in a manner similar to human vision. RobotAI has established projects and paid proof of concepts with notable clients, including Whirlpool, Denso, ABB, Ford, and Deutsche Telekom, showcasing its impact across various industries.

TechnoCarbon Technologies France is a French startup that specializes in developing high-performance, low-carbon-footprint composite materials. Their flagship product, CarbonFibreStone™ (CFS™), aims to revolutionize the architecture and industry sectors by providing an eco-friendly alternative to traditional materials such as reinforced concrete, steel, and aluminum. These conventional materials are known for their intensive air pollution and depletion of natural resources. TechnoCarbon's patented technology enables the creation of a new family of materials suitable for various applications, including construction, infrastructure, aerospace, defense, luxury goods, furniture, and HiFi audio. By offering high-performance composite materials, TechnoCarbon helps industrial clients achieve technical performance while saving energy and natural resources, all with a significantly lower carbon footprint.

Rapid Liquid Print is working on 3D printers that create stretchy products for industrial materials. Their services include medical devices, footwear, home goods, furniture, aviation, and automotive components.

re:3D reduces production complexity by providing affordable, industrial 3D printers that transform big ideas into tangible realities. With a build volume of eight cubic feet and robust construction, Gigabot can print objects 30x larger than competing desktop models. Up until now, personal 3D printing has been limited to toys and trinkets, while the Gigabot will bring your biggest dreams to life. re:3D's customer base comprises an esteemed group of designers, small business owners, manufacturers, educators, prototypists, and hobbyists in over 30 countries around the globe. Currently, re:3D is scaling manufacturing operations, and exploring alternate materials and feedstocks with global leaders in material and life sciences.

USEFULL is a company dedicated to creating a zero-waste future by eliminating plastics and single-use packaging within college and corporate dining operations. It offers a sustainable solution through its stainless steel, returnable takeout containers, designed for ease of use akin to checking out a library book. These containers are durable and can be used for at least three years before being recycled, contributing to significant reductions in waste, water usage, and emissions. By integrating a proprietary application, USEFULL simplifies the checkout and return process, enabling organizations to save money while effectively promoting their sustainability initiatives and driving lasting behavior change among customers.

Naya’s platform brings the entire physical product design journey into one digital studio, from prompt to product, allowing teams to 10x their outcomes — speed, cost, and customer love.

Scott Massey met Ivan Ball while working together on a NASA funded research project at Purdue University in an effort to create life support systems for future space colonies. What started as an introduction to an the innovating technology of hydroponics, left them both wondering why there was not a standard, aeroponic device for consumers to grow their own produce. After extensively researching patents of existing systems on the market, Scott and Ivan realized that the design they were drawing out on napkins had not yet been conceived. It was at that moment, Heliponix™ (formerly Hydro Grow) was founded. What started as a dream for these young engineers who wanted to make a difference in the world became a literal kitchen startup in an apartment on campus at Purdue University as Ivan and Scott built their initial prototypes which were funded by working night shifts as full-time students.

Enzymit is a biotechnology company focused on revolutionizing global manufacturing through sustainable and efficient bio-production methods. It specializes in developing cell-free bio-production technology that aims to eliminate the inefficiencies and complexities associated with traditional bio-production. Enzymit employs artificial intelligence and deep learning algorithms to design novel enzymes, which serve as molecular machines capable of transforming abundant feedstocks into valuable products, including pharmaceuticals, cosmetics, food, and materials. The company’s small, modular bio-reactors facilitate this process, promoting resource independence while minimizing environmental impact. By moving away from conventional whole-cell methods to utilizing nature's elemental building blocks, Enzymit enhances cost-effectiveness, efficiency, and sustainability in bio-production, while also providing greater flexibility in product customization for various industries.

Polybion manufactures sustainable bio-assembled materials using waste as a raw material. Their products aim to reduce environmental impact by replacing petroleum- or animal-derived textile materials, enabling designers and engineers to enhance sustainability.

Rezztek is a company focused on enhancing the performance of hockey players through innovative equipment. It manufactures hockey stick blades designed to improve puck control and facilitate faster, more accurate shots. Rezztek emphasizes customization, allowing players to tailor products to their specific needs. Additionally, the company offers a platform for branding and advertising, aiming to elevate the marketing and visibility of hockey-related products. Through its commitment to high-quality materials and performance enhancement, Rezztek seeks to redefine the standards of hockey equipment and promote the sport effectively.

māk studio is an interior design company that specializes in providing fabrication and design services. The company focuses on creating custom and customizable furniture for commercial interiors, offering impressive interior elements such as branding walls and tailored furniture that align with each client's unique vision and brand. With the launch of its new online platform, māk tech, the company aims to simplify the design-to-production process, making these sophisticated interior solutions accessible to a broader audience.

Rhythmo is a company focused on educating teenagers in music and STEM through innovative products. It manufactures music production instruments, including a MIDI drum machine and speaker combo, packaged in a cardboard box. This offering is accompanied by an application, sound packs, and tutorials, making it an accessible and cost-effective solution for young learners interested in music production. Rhythmo's products are designed to encourage creativity and customization, providing a hands-on approach to music education while integrating technology and engineering concepts.

MDM Wound Ventures Inc. is a medical device manufacturing company based in Schertz, Texas, focused on developing innovative products for wound care and surgical applications. The company is known for its EZ Debribe, a sharp debridement instrument designed to provide clinicians with a precise and disposable option for debriding wounds. Founded in 2014, MDM Wound Ventures aims to enhance patient outcomes while reducing costs in the healthcare sector. The company specializes in manufacturing debridement equipment characterized by a uniform cutting plane and cutting flutes, allowing for effective and efficient wound treatment.

Hangio is a manufacturer specializing in innovative clothing hangers designed to preserve garments' quality. Their hangers are flexible, durable, and adaptable to various collar types and neckline depths, preventing damage such as shoulder bumps, slippage, wrinkles, creases, and collar stretching.

Multiscale Systems produces industrial innovations through technical engineering services and a robust in-house R&D program. The company specializes in metamaterial composites and focuses on advanced manufacturing.

Invent Boston design, manufactures and supplies every day routines.

Watttron GmbH is a technology company based in Freital, Germany, that specializes in the development and production of advanced heating systems designed for applications requiring high precision in temperature control. Established in 2016, Watttron offers innovative matrix heating and sealing systems, as well as customized heating solutions and simulation services. Its patented technology allows for heterogeneous heating, which is beneficial in various industrial processes, including polymer processing, packaging, additive manufacturing, microelectronics, biotechnology, automotive, and medicine. The company's focus on energy efficiency and precise temperature management enables clients to effectively process bio-based and recycled materials, positioning Watttron as a leader in the field of intelligent heating solutions.

MakersValley is an online B2B platform that connects apparel manufacturers with fashion designers globally. It aims to democratize manufacturing by providing access to high-end Italian manufacturers and personalized guidance throughout the production process.

Magnomer is a Boston-based manufacturer specializing in innovative magnetic inks designed to enhance the recyclability of plastic packaging within a circular economy framework. Founded in 2017, the company has developed a product called Design2Recycle™, which serves as a design tool for consumer brands and manufacturers. This technology incorporates printable magnetizable inks that improve the recyclability of multi-layer plastics without necessitating changes in existing manufacturing processes. By offering coatings for inks used in such packaging, Magnomer enables recycling facilities to more effectively separate these materials using magnetic sorting technology, addressing the challenges posed by traditional recycling methods.

Folia Water, Inc., established in 2016 and based in Pittsburgh, Pennsylvania, is a manufacturing company specializing in affordable water filtration solutions. The company's core product, Folia Filters™, is an innovative water filter made from antimicrobial filter paper infused with silver nanoparticles. This patented technology, which transforms ordinary paper into a super material, enables Folia Water to produce low-cost filters that reduce waterborne pathogens, making clean drinking water accessible to a broader range of consumers, particularly those in developing regions. The company's mission is to improve global health and sustainability by providing high-quality, affordable water filtration products.

ApreX Biotech is a developer of advanced organs-on-chips systems aimed at transforming pharmaceutical development and personalized medicine. The company specializes in utilizing innovative origami folding techniques to create intricate 3D tissue architectures from simple, easily manufactured 2D patterns. This technology enables ApreX Biotech to facilitate the advancement of products across various sectors, including pharmaceuticals, chemicals, food, and cosmetics. By providing a cutting-edge platform for in vitro testing, ApreX Biotech supports clients in developing more effective and tailored solutions in their respective industries.

The 1854 Cycling Company manufactures high-performance electric cycles designed for consumers seeking confidence and resilience in challenging environments. They also provide accessories to enhance cycling experiences, promoting health and fitness.

Takachar is a company focused on transforming agricultural waste into valuable products, particularly eco-friendly cooking fuel. Operating primarily in Kenya, it has developed low-cost technologies that enable the conversion of unmanaged agricultural residues into charcoal, a non-toxic and affordable energy source for low-income households. Over the past three years, Takachar has established or assisted seven locally run waste-to-charcoal enterprises, some of which have achieved operational profitability. The company has successfully created approximately 100 jobs and sold 50 tons of its eco-char product. By utilizing oxygen-lean torrefaction reactors, Takachar helps farmers reduce waste through recycling, allowing them to generate additional income while preventing open burning of agricultural residues. The company aims to demonstrate the financial sustainability of these enterprises as a foundation for expanding its franchise network in the future.

MotionTech is a company that has developed innovative silicone 3D printing technology aimed at transforming the orthopaedic industry. It offers a service known as "Your Liner," which enables prosthetic technicians globally to order customized silicone equipment tailored to the specific needs of their patients. MotionTech addresses the issue of prosthetic discomfort by providing a 3D scanner that captures the precise shape of a patient's stump. This data is then utilized to create a custom-made silicone sleeve that redistributes pressure and minimizes friction, enhancing comfort for the user. By promoting mass customization over traditional mass production, MotionTech seeks to drive a significant shift in orthopaedic care, ultimately improving the quality of life for individuals requiring prosthetic solutions.

Social Fabric is a sustainable textile center committed to promoting the use of textiles and clothing that minimize ecological and social footprints. The company operates a community-based association that emphasizes the integration of refugees in Switzerland and sustainability in textile production. Through its atelier, Social Fabric aims to provide customers with meaningful and customized garments that reflect principles of a circular economy, innovative technology, and ethical labor practices. By combining decentralised manufacturing with a focus on sustainability, Social Fabric enables individuals to access high-quality, sustainable textile products tailored to their needs.

Founded in 2018, Komp-ACT specializes in manufacturing electric motion technologies for the automation industry. Its flagship product, Modula, is an innovative electric actuator solution designed to reduce weight and maintenance costs while minimizing energy consumption and CO2 emissions.

Novamet Sarl, established in 2014 and located in Saint-Sulpice, Switzerland, specializes in optimizing aluminum melting and recycling processes through its innovative data-driven platform. The company offers a product called SmartMelt, which utilizes online data acquisition, numerical modeling, and machine learning to enhance the efficiency of industrial furnaces in the aluminum sector. By integrating real-time data analysis with advanced simulation techniques, Novamet's system collects information from sensors placed within melting furnaces. This enables the prediction of optimal melting cycles, allowing aluminum and metallurgy plants to improve energy efficiency and overall productivity during production.

MotionTech is a company that has developed innovative silicone 3D printing technology aimed at transforming the orthopaedic industry. It offers a service known as "Your Liner," which enables prosthetic technicians globally to order customized silicone equipment tailored to the specific needs of their patients. MotionTech addresses the issue of prosthetic discomfort by providing a 3D scanner that captures the precise shape of a patient's stump. This data is then utilized to create a custom-made silicone sleeve that redistributes pressure and minimizes friction, enhancing comfort for the user. By promoting mass customization over traditional mass production, MotionTech seeks to drive a significant shift in orthopaedic care, ultimately improving the quality of life for individuals requiring prosthetic solutions.

Sea Machines Robotics, headquartered in Boston, Massachusetts, specializes in developing and manufacturing advanced autonomous control and navigation systems for the commercial marine industry. Established in 2014, the company produces systems like SM300 for remote vessel command, SM200 for collaborative operations, SM400 for AI-powered situational awareness on container ships, RC NXT for PLC-based wireless control, and DP-NXT for crew reduction or elimination on vessels. Sea Machines offers solutions for various unmanned applications, including bathymetric surveys, AUV-tendering, subsea asset inspection, passive acoustic monitoring, and dual towing.

Facterra specializes in collaborative performance management software tailored for the manufacturing industry, focusing on industrial after-sales services and asset management. The company offers a cloud-based platform that integrates asset management, maintenance, and energy and water management functions. This user-friendly system enables manufacturing businesses to mobilize staff across maintenance, quality, and production teams, facilitating cross-functional initiatives. By connecting various data sources, including ERP systems and automation tools, Facterra enhances operational efficiency. Its solutions are designed to optimize asset performance and maintenance activities, thus supporting both machine builders and producers in the food and beverage sector.

PrintCB specializes in developing copper inks for printed electronics manufacturing. Its innovative materials replace silver, significantly reducing production costs in a $70B market. Based in Ness Ziona, Israel.

HICS provides real-time nano-accuracy measurement and inspection solutions. Founded in 2014 and based in Seoul, South Korea, the company developed a machine-vision platform backed by 3D-NDM/R and 3D-NDM/T technology that measures nanoscale depth and detects defects and foreign materials in real time, supplying quantitative data on 3D nanoscale defects to enable industries such as LED panel manufacturing to perform rigid nano inspection with enhanced speed and accuracy.

Tangi0 Ltd is a London-based company that specializes in the research, development, and manufacturing of an innovative touch-sensitive material designed to replace traditional electronic sensors. Founded in 2015, Tangi0's technology provides a flexible solution for creating three-dimensional controls that are ergonomic, intuitive, and engaging. The company's manufacturing process is assembly-free and cost-effective. Tangi0 is actively developing a range of computer peripheral products and seeking joint development partnerships with major players in the automotive and gaming sectors, aiming to enhance the functionality and user experience of various applications.

Insolight is an energy company founded in 2015 that specializes in the development and manufacturing of advanced solar panels. The company has achieved record efficiency levels of 29 percent for its solar modules, significantly lowering residential solar electricity costs. Insolight utilizes innovative optical technology that combines high efficiency with the ease of mounting similar to standard flat panels. The company has also demonstrated its capabilities through third-party validations, achieving 36 percent efficiency on lab prototypes and 29 percent on pre-industrial modules. Insolight's business model focuses on developing intellectual property, controlling wholesale distribution, and outsourcing manufacturing. Additionally, the company is engaged in creating photovoltaic systems aimed at reducing solar electricity costs in the agricultural sector, employing integrated tracking methods to optimize energy production based on the sun's position.

Distran develops advanced acoustic sensing technology to improve safety and environmental performance in industrial settings. Originating from ETH Zurich's Autonomous System Lab, the company creates phased-array ultrasound sensors that spatially filter background noise to locate defects such as leaks or discharges from a safe distance, addressing limits of traditional sensors. The technology enables remote, early defect detection and non-contact monitoring, supporting safer work practices and reduced environmental impact. Distran serves industries including oil and gas, power generation, chemistry, and composite engineering, helping operators monitor machinery, identify issues promptly, and optimize maintenance. By combining directional sensing with robust performance in noisy environments, the company aims to enhance reliability, protect workers, and lower the environmental footprint of industrial operations.

Fortify is an advanced manufacturing startup focused on transforming additive manufacturing by producing custom, high-performance products. The company has developed a patented technology that integrates 3D printing with magnetics to create aligned reinforced carbon fiber composites. Using a combination of digital light processing and magnetic techniques, Fortify enables engineers to design and manufacture items with optimized material properties tailored for specific applications. Its product offerings range from injection mold tooling to high-performance components suitable for demanding environments. Fortify's innovative approach allows digital component manufacturers to access durable and high-performance composites more efficiently and at reduced costs.

Tranquilo, Inc. is a company based in Tampa, Florida, that specializes in the design and manufacture of portable and vibrating mats aimed at soothing babies and facilitating quicker sleep. Founded in 2015, the Tranquilo Soothing Mat is lightweight and portable, making it convenient for parents to use while traveling or on the go. The mat mimics the sounds and motions of a mother's womb, providing a calming effect for crying infants. As of November 28, 2018, Tranquilo operates as a subsidiary of Baby Boom Consumer Products, Inc.

Stokes Firestarters specializes in manufacturing all-natural, non-chemical fire starters made from recycled pulp, wax, and sustainably harvested wood sawdust. The company emphasizes environmentally friendly practices by utilizing only natural materials, ensuring a safe and reliable way to ignite fires. Initially created as holiday gifts using household materials, Stokes Firestarters has grown significantly and is now available in over 300 retail locations across eight states, including prominent retailers such as Whole Foods, Market Basket, Stop and Shop, and Shaws. The fire starters are designed for use with wood and charcoal, providing effective ignition with just one match. Stokes Firestarters are produced in Natick, Massachusetts, in collaboration with Charles River Industries.

Induo is a textile company that specializes in the development and sale of innovative fabrics designed for apparel brands. The company's flagship product, INDUO® fabric, utilizes invisible technology to create cotton materials that are both stain and perspiration resistant. This unique approach allows Induo to maintain the soft touch and comfort associated with high-end cotton while also focusing on sustainability by recycling complex material blends and poorly sorted apparel waste. By providing breathable and durable fabrics, Induo enables its customers to enjoy comfortable clothing at an affordable price.

RethinkResource is a company focused on developing a cross-industrial smart sourcing platform designed for producing companies. The platform aims to facilitate the implementation of a circular economy by transforming industrial side-streams into sustainable and innovative products. RethinkResource offers services in innovation management, product development, and circular engineering, enabling producers and brand owners to responsibly manage their material streams. Through its efforts, the company aspires to foster resource stewardship and support the emergence of industry leaders committed to sustainable practices.

Induo is a textile company that specializes in the development and sale of innovative fabrics designed for apparel brands. The company's flagship product, INDUO® fabric, utilizes invisible technology to create cotton materials that are both stain and perspiration resistant. This unique approach allows Induo to maintain the soft touch and comfort associated with high-end cotton while also focusing on sustainability by recycling complex material blends and poorly sorted apparel waste. By providing breathable and durable fabrics, Induo enables its customers to enjoy comfortable clothing at an affordable price.

Danger!Awesome LLC, incorporated in 2014 and located in Cambridge, Massachusetts, specializes in laser-cutting and engraving services for a diverse range of materials, including wood, plastic, paper, and leather. The company caters to a wide array of clients, such as architects, artists, engineers, students, and small business owners. In addition to its core services, Danger!Awesome is developing an innovative super-powered professional solid-state laser cutter designed to deliver high performance at a consumer-friendly price point. This new device aims to replace traditional CO2-based laser systems, which are often prohibitively expensive, making laser technology more accessible to libraries, schools, and community spaces. The company also offers a membership-based community makerspace, allowing customers to collaborate with designers and technicians to create customized products tailored to their specific needs.

MagnebotiX, founded in 2014 and based in Zurich, specializes in the development and production of advanced magnetic manipulation systems. The company focuses on creating magnetic field generators and micromagnetic agents, utilizing their extensive expertise in the field. Their innovative products are designed to facilitate both fundamental and applied scientific research, enabling users to perform complex micromanipulation tasks wirelessly. MagnebotiX’s systems are particularly valuable as untethered mechanical probes, allowing access to otherwise unreachable areas and enabling targeted cargo delivery for minimally invasive biological studies. By leveraging the transmission of power and guidance through applied magnetic fields, MagnebotiX supports a wide range of research applications in the field of magnetic phenomena and magnetic microrobots.

Response Technologies, LLC, founded in 2015 and based in Coventry, Rhode Island, specializes in additive manufacturing and advanced material science. The company focuses on developing innovative techniques for creating 3D textile structures and reinforced composites, which are particularly beneficial for industries such as national defense, energy, aerospace, automotive, and transportation. One of its key products includes explosion-resistant fuel tanks, which enhance safety and effectiveness in fuel containment. As a subsidiary of Bell Textron Inc., Response Technologies is committed to addressing the material science and additive manufacturing needs of diverse sectors, ensuring that clients receive high-quality fuel cells and components tailored to their specific requirements.

Flying Spark Ltd, established in 2014 and headquartered in Ramat Gan, Israel, specializes in the production of protein powder derived from fruit fly larvae. The company's primary products are dietary protein whole powder, reduced fat powder, and oil, all of which are rich in essential nutrients like iron, calcium, magnesium, and dietary fibers, as well as amino acids. These products cater to various industries, including food and feed for human consumption, and cosmetics, due to their white color, mild taste, and aroma, which facilitate easy incorporation into diverse applications.

Blackburn Energy develops and manufactures RelGen, a vehicle electrification technology that converts the kinetic energy from a truck's drive shaft into electricity stored in a battery array to power truck subsystems such as electric APUs, liftgates, climate control, and sensors. The RelGen system, along with a 48V charging platform and anti-idling solutions, enables fleets to reduce fuel use, lower maintenance costs, and cut emissions by powering accessories without engine idle. The company promotes integrated systems including kinetic energy recovery, electric AC, and heat recovery, and serves commercial trucking fleets, liftgates and bucket service vehicles, and fleets supporting overnight accommodations and driver-assist features. Based in Amesbury, Massachusetts, Blackburn Energy was established in 2008 and has provided electrification solutions to large users including fleets associated with General Motors, AB InBev, and the US Marines.

New Valence Robotics Corporation, founded in 2013 and based in Boston, Massachusetts, specializes in designing and leasing advanced 3D printing solutions. As a subsidiary of Cincinnati Incorporated, the company focuses on delivering innovative automated enterprise 3D printing technologies to address significant industry challenges. Their research and development program, NVLABS, has pioneered the capability to print with multiple metals in a single build, including materials such as stainless steel and titanium. The flagship product, NVPro™, is recognized as the world's first fully automated end-to-end 3D printing solution, featuring patented automated part removal and the ability to operate continuously around the clock. This technology allows users to achieve ultra-high printing speeds, significantly exceeding current market offerings, and provides a cost-effective solution while enhancing accessibility and usability through a cloud-based interface.

Mebotics is a technology company specializing in hybrid desktop manufacturing solutions that integrate 3D printing and CNC milling capabilities. Their innovative machines enable additive manufacturing using multiple plastics, as well as subtractive manufacturing with woods and metals. Designed with a rugged and self-cleaning chassis, these machines feature a fully networkable onboard computer and a range of safety features, making them suitable for diverse environments such as labs, offices, and outdoor settings. Mebotics aims to democratize access to advanced machine-shop technologies, providing prototypers and small-scale manufacturers with affordable and versatile manufacturing options.

PolyDrop develops conductive polymer additives for coatings, composites, and batteries. Originating at the University of Washington, its patented material science enables safe, stable, and affordable conductive polymers. The additives provide anti-static and anti-corrosion protection at low loading, enabling existing coatings and plastics to become static-dissipative in electronics, marine, textiles, flooring, and related applications. The technology has been integrated in electronics and coatings industries, transforming coatings and plastics into dissipative materials while maintaining performance and cost efficiency.

Eulysis UK Limited is a device development company dedicated to enhancing the storage and delivery of pharmaceutical products. The company has introduced a revolutionary product known as the Single Vial System, which employs an innovative manufacturing process. This system enables the combination of a lyophilized active ingredient and its diluent for reconstitution within a single container. Traditionally, pharmaceutical products like vaccines and antibiotics have been stored and delivered in two separate containers, leading to inefficiencies and heightened risks such as contamination and increased raw material usage. By consolidating the components into one vial, Eulysis aims to streamline production, reduce transportation and storage costs, and minimize potential safety concerns.

Voxel8 Inc. is a Somerville, Massachusetts-based company that specializes in designing and manufacturing advanced electronic devices and digital 3D printing technologies. Incorporated in 2013, Voxel8 offers desktop 3D printers that utilize thermoplastics and UV resins, enabling the rapid fabrication of customizable electronic devices. The company's proprietary Project Wire software facilitates the design of 3D printable electronics, streamlining the production process. Voxel8's unique technology is particularly applicable in textile applications, allowing for the zonal tuning of mechanical properties and the enhancement of aesthetic features in products such as footwear, apparel, and medical devices. This additive manufacturing approach minimizes waste and supports sustainability through the use of bio-based materials. Voxel8's innovations enable customization of individual prints, enhancing performance characteristics like abrasion resistance, cushioning, and grip, while also incorporating full-color graphics and 3D embellishments. The technology was developed in collaboration with Professor Jennifer Lewis at Harvard University, positioning Voxel8 at the forefront of digital manufacturing in the textile and electronic sectors.

DropWise Technologies Corp. is a manufacturer of advanced coating materials aimed at enhancing the efficiency and longevity of heat exchange equipment in various industries, including power generation and HVAC/R. The company utilizes a unique vapor-based deposition process to create ultra-thin, durable coatings that are chemically grafted to metal surfaces, significantly improving thermal transport and reducing fouling and corrosion. This innovative technology allows power plants to generate the same amount of electricity while using less coolant water, thereby helping to offset carbon emissions. By offering coatings that are hundreds of times thinner than conventional solutions, DropWise addresses critical challenges in thermal fluid systems, allowing for increased heat transfer and operational efficiency. Established in 2014 and headquartered in Cambridge, Massachusetts, DropWise Technologies leverages intellectual property from leading MIT labs to develop a diverse library of coating materials tailored for various applications, including desalination and chemical refining.

Ashton Instruments is a startup based in Cambridge that specializes in the manufacturing of advanced cycling power meters. Their innovative product is designed to be easily inserted into the hollow spindles of SRAM or FSA cranksets for both road and mountain bikes, utilizing a plug-and-play form factor. The power meter functions as a reliable training and performance tracking tool for cyclists, incorporating features such as auto-zeroing and temperature compensation to ensure accurate data across various riding conditions. Equipped with both ANT+ and Bluetooth connectivity, the device is constructed from durable aluminum and is installed in the bottom bracket, making it a robust solution for cyclists seeking to enhance their performance metrics.

Flatev AG is a Swiss company that specializes in the manufacturing of innovative tortilla makers and dough pods. Since its incorporation in 2012, the company has developed a unique machine capable of preparing fresh tortillas and other flatbreads within a minute, utilizing a pod system akin to that of a coffee machine. This technology allows users to transform capsules of dough into high-quality bread, reminiscent of handmade varieties, eliminating the need for pre-packaged options. Flatev's product line includes various types of tortilla dough pods, such as corn and flour. The company aims to distribute its machines through department stores, kitchen supply retailers, and wholesale warehouse clubs, while its dough pods will be available in grocery stores. With offices in Zurich, Switzerland, as well as Bridgeton and Brooklyn in the United States, Flatev is positioned to bring a taste of authentic flatbreads to homes and food establishments alike.

Lallitara is an environmentally conscious apparel brand that specializes in creating stylish, one-of-a-kind products by upcycling vintage sari fabrics. The company offers a range of eco-friendly apparel, accessories, and home products that allow customers to express their personal style while supporting sustainable practices. By repurposing traditional Indian saris, Lallitara not only provides unique fashion options but also contributes to the livelihoods of India's informal recycling community by ensuring fair wages. Additionally, the brand emphasizes domestic manufacturing, aligning itself with the 'Made in America' movement. Overall, Lallitara combines fashion with a commitment to social and environmental responsibility.

CONTINUUS Pharmaceuticals, Inc. specializes in integrated continuous manufacturing technology for small molecule pharmaceuticals. Founded in 2012 and based in Woburn, Massachusetts, the company operates under a Build-Own-Operate model, collaborating with pharmaceutical and generic companies to design, build, and manage manufacturing processes directly at client sites. This approach provides clients with a comprehensive solution for their development and manufacturing needs. CONTINUUS leverages its Integrated Continuous Manufacturing (ICM) platform, which was initially developed through a significant research initiative involving Novartis and MIT. Additionally, the company is working with hospital systems and pharmacy chains to create a generic drug business that focuses on producing high-quality, low-cost medications in the United States. By employing advanced technologies, CONTINUUS aims to reduce pharmaceutical costs and enhance manufacturing efficiency.

Veraquel Technologies is commercializing a transformative platform technology for the synthesis and manufacturing of peptides, applicable from discovery to large-scale production. This patented technology has the potential to eliminate the need for labor-intensive column separations, revolutionizing the process of manufacturing scale-up and enabling the high-throughput parallel purification of peptides for library-based approaches to drug discovery.

DrinkSavvy is a Boston-based company that manufactures and distributes drinkware such as plastic cups, straws, and stirrers. Its products feature a proprietary, patented technology, integrating indicators into barware in order to provide consumers with a colorimetric indication of the presence of illicit drugs such as GHB, Ketamine, and Rohypnol in their drink. DrinkSavvy was founded in 2009 and is based in Boston, M.A.