National Institutes of Health

National Institutes of Health is a biomedical research agency of the U.S. Department of Health and Human Services, based in Bethesda, Maryland. It is the primary U.S. government organization devoted to biomedical and health research, conducting science through the Intramural Research Program and funding external research through the Extramural Research Program. The NIH comprises 27 institutes and centers and supports about 1,200 principal investigators and more than 4,000 postdoctoral fellows across basic, translational, and clinical research. It has contributed to major advances such as vaccines and therapies and is dedicated to advancing knowledge and translating discoveries into improvements in public health. Established in 1887, NIH operates as a central hub for medical research in the United States.

Francis Collins

Director

Nick Langhals

Supervisory Program Director

Past deals in Eastern US

Feinstein Institute for Medical Research

Grant in 2025
Feinstein Institute For Medical Research is the research arm of Northwell Health, the largest health care provider and private employer in New York State. Home to 50 research labs, 3,000 clinical research studies and 5,000 researchers and staff, the Feinstein Institutes raises the standard of medical innovation through its five institutes of behavioral science, bioelectronic medicine, cancer, health innovations and outcomes, and molecular medicine. We make breakthroughs in genetics, oncology, brain research, mental health, autoimmunity, and are the global scientific leader in bioelectronic medicine – a new field of science that has the potential to revolutionize medicine.

Mount Sinai Health System

Grant in 2024
Mount Sinai Health System is an integrated healthcare system based in New York, providing exceptional medical care to local and global communities. Established in 2013 through the merger of Mount Sinai Medical Center and Continuum Health Partners, it encompasses the Icahn School of Medicine and operates seven hospital campuses throughout the New York metropolitan area. The system is recognized for its excellence in research, patient care, and education across various specialties. It features a vast network of over 7,000 primary and specialty care physicians, as well as more than 45 ambulatory practices and 12 minority-owned free-standing ambulatory surgery centers. Mount Sinai is committed to improving healthcare quality and accessibility, focusing on compassionate patient experiences and the development of strong relationships between staff and patients. Additionally, its venture capital arm, Mount Sinai Ventures, invests in healthcare startups, further enhancing its capacity to innovate and respond to the diverse health needs of the populations it serves.

Allyx Therapeutics

Grant in 2024
Allyx Therapeutics, Inc. is a clinical-stage biotechnology company founded in 2018 and based in Durham, Connecticut. The company specializes in developing disease-modifying treatments for Alzheimer's Disease, with a focus on reversing neurodegeneration. Its lead product is an orally bioavailable small molecule that functions as a silent allosteric modulator of mGluR5. This innovative approach aims to provide clinicians with a therapeutic option capable of preserving cognition in patients while addressing the underlying disease mechanisms.

CytoAgents

Grant in 2024
CytoAgents is a clinical-stage biotechnology company focused on developing innovative pharmaceutical products for treating life-threatening symptoms associated with Cytokine Release Syndrome (CRS), an overreaction of the immune system causing systemic inflammation.

TransCode Therapeutics

Grant in 2024
TransCode Therapeutics, founded in 2016 and based in Boston, Massachusetts, is a biopharmaceutical company dedicated to discovering, developing, and commercializing innovative RNA therapeutics for treating metastatic cancer. Its lead therapeutic candidate targets an RNA molecule that drives metastatic disease across multiple tumor types.

Weill Cornell Medicine

Grant in 2024
Weill Cornell Medicine is a renowned academic medical center dedicated to excellence in patient care, scientific discovery, and educating future physicians. With over 300 IT professionals supporting more than 10,000 users across its institutions, it offers comprehensive technology services, including infrastructure management, security, networking, software development, and innovative solutions for clinical and research projects.

Phenomix Sciences

Grant in 2024
Founded in 2017, Phenomix Sciences is a biotechnology company specializing in metabolomics and genomics. It develops precision medicine tools for chronic disease management, focusing on obesity. The company's AI-driven platform offers a novel blood test to classify patients' unique pathophysiological phenotypes, enabling personalized treatment with improved efficacy and fewer side effects.

Behaivior

Grant in 2024
Behaivior LLC is a digital health company based in Pittsburgh, Pennsylvania, focused on predicting and preventing addiction relapses through innovative technology. Founded in 2017, Behaivior integrates wearable devices with machine learning algorithms to analyze real-time data from various physiological metrics, such as heart rate and skin temperature. The company’s platform, known as Recovery, employs this data to deliver timely interventions tailored to the needs of individuals in recovery. By utilizing a SaaS business model, Behaivior aims to democratize mental health recovery and support, assisting users in maintaining their wellness while enabling care providers to enhance their service delivery. Through its proactive approach, Behaivior seeks to improve mental health outcomes and reduce crisis events associated with addiction.

New York Society for the Prevention of Cruelty to Children

Grant in 2023
Founded in 1875, this organization provides counseling, legal aid, and educational resources to protect and support children in need across New York City.

Integral Molecular

Grant in 2023
Integral Molecular, Inc. is a biotechnology company headquartered in Philadelphia, Pennsylvania, specializing in the development of innovative technologies for drug discovery targeting challenging diseases such as cancer, HIV, and arthritis. The company is particularly known for its Lipoparticle technology, which enhances the identification and optimization of drugs aimed at integral membrane proteins. With over 20 years of expertise in membrane proteins and antibodies, Integral Molecular has supported more than 400 pharmaceutical and biotechnology companies in their research, medication discovery, and vaccine development efforts. The company's solutions are integral to various stages of the drug discovery process, focusing on the development of chemical compounds and antibodies.

Actinium Pharmaceuticals

Grant in 2023
Actinium Pharmaceuticals is a biopharmaceutical company focused on developing and commercializing therapies for life-threatening diseases using its alpha particle immunotherapy platform. Its lead product candidates include Iomab-B, in Phase III trials as an induction agent for elderly AML patients prior to bone marrow transplant, and Actimab-A, in Phase II trials for newly diagnosed AML patients aged 60 and over.

Boston University Chobanian & Avedisian School of Medicine

Grant in 2023
Boston University Chobanian & Avedisian School of Medicine is a school of medicine focus on treating disadvantaged and underserved populations.

Daxor

Grant in 2023
Daxor Corporation is a medical device and biotechnology company based in New York, founded in 1970. It specializes in blood volume measurement, offering the BVA-100 Blood Volume Analyzer, the first FDA-approved instrument for the rapid and direct measurement of a patient's true blood volume. This device is utilized in diagnosing and managing various medical conditions, including congestive heart failure, critical care medicine, hypertension, and anemia. In addition to its core product, Daxor provides cryobanking services such as semen banking and blood storage, along with andrology and general laboratory testing services. The company also collaborates with the Uniformed Services University of the Health Sciences to research the effectiveness of its diagnostic tests in traumatic injury contexts. Daxor was previously known as Idant Corporation before rebranding in May 1973.

Boston Immune Technologies & Therapeutics

Grant in 2023
Boston Immune Technologies & Therapeutics, Inc. is a biopharmaceutical company focused on developing immune-based therapies for cancer and infectious diseases. Incorporated in 2011 and located in Winchester, Massachusetts, the company has created a platform that targets the tumor necrosis factor receptor 2 (TNFR2) oncogene and the specific population of TNFR2 regulatory T cells within the tumor microenvironment. This innovative approach aims to enhance immunotherapy strategies, particularly for chronic infectious diseases, by leveraging the body's immune system to combat various health challenges.

Columbia Investment Management Company

Grant in 2023
Columbia Investment Management Company is a wholly owned subsidiary of Columbia University based in New York City. Established in 2002, it serves as the university’s investment arm, responsible for the long-term management of the endowment and other assets, while excluding real estate holdings and certain charitable giving vehicles with investment restrictions. The organization is governed by Columbia University’s board of trustees and operated by an executive management team, reflecting a commitment to high professional standards in institutional asset management.

Applied BioMath

Grant in 2023
Applied BioMath, LLC, established in 2013 and headquartered in Concord, Massachusetts, specializes in systems biology and pharmacology services aimed at accelerating drug research and development for biotechnology and pharmaceutical companies. The company employs advanced mathematical modeling and simulation techniques to provide predictive guidance and insights throughout the drug discovery process. Its offerings include pathway model development, target and biomarker discovery, and feasibility assessments for various drug targets. Additionally, Applied BioMath conducts analyses of competitor compounds and projects drug properties and dosing for clinical phases. The firm utilizes proprietary algorithms and high-performance computational biology to optimize decision-making and mitigate risks associated with late-stage attrition in drug development. With additional offices in Cambridge and Oakland, Applied BioMath collaborates strategically with industry leaders such as Sanofi and Xilio Therapeutics to enhance its service offerings.

MaineHealth

Grant in 2023
MaineHealth is a not-for-profit family of leading high-quality providers and other healthcare organizations working together so our communities are the healthiest in America. Ranked among the nation's top 100 integrated healthcare delivery networks, MaineHealth member organizations include Maine Medical Center, Franklin Community Health Network, LincolnHealth, Maine Behavioral Healthcare,

Advent Therapeutics

Grant in 2023
Advent Therapeutics specializes in developing therapies for micro-orphan indications, focusing on unmet medical needs in neonatal and pediatric patient populations. Based in Lumberville, Pennsylvania.

Barrett Technology

Grant in 2023
Barrett Technology, LLC, established in 1990 and located in Newton, Massachusetts, specializes in the design and manufacture of advanced robotic manipulators. The company has pioneered technology that enhances flexibility in articulated arms and hands, positioning itself as a leader in this field. Renowned for its innovative solutions, Barrett Technology earned recognition in the Guinness Book of World Records for its advanced manipulator technology. The company offers a high degree of versatility, catering to a wide range of applications across various industries.

Aphios

Grant in 2023
Aphios Corporation is a biotechnology company based in Woburn, Massachusetts, specializing in drug delivery platforms and the development of quality-of-life medicines. The company focuses on enhancing drug discovery and manufacturing through its innovative biotechnology and nanotechnology solutions. Aphios offers a range of therapeutic products aimed at health maintenance, disease prevention, and the treatment of various conditions, including cancers, infectious diseases, and central nervous system disorders. Notable products include Zindol, a ginger-based product, and various formulations of Taxotere for cancer treatment, which aim to improve oral bioavailability and target specific cancer cells. In addition to its therapeutic offerings, Aphios develops advanced technologies such as SuperFluids for pharmaceutical manufacturing and virology testing services, contributing to the safety and efficacy of drug therapies. Founded in 1993, Aphios continues to push the boundaries of medical science with its focus on innovative solutions for complex health challenges.

Sapphiros

Grant in 2023
Sapphiros is a private equity growth and expansion firm founded in 2021 and based in Massachusetts. The company specializes in investing in growth-stage diagnostic companies, emphasizing innovative and patient-centric technologies. Its portfolio includes a diverse range of capabilities, such as advanced sample collection methods, next-generation diagnostics, computational biology, and printed electronics. By focusing on these areas, Sapphiros aims to enhance the global accessibility of essential diagnostic results for consumers, thereby contributing to advancements in healthcare and diagnostic-related innovations.

Feinstein Institute for Medical Research

Grant in 2023
Feinstein Institute For Medical Research is the research arm of Northwell Health, the largest health care provider and private employer in New York State. Home to 50 research labs, 3,000 clinical research studies and 5,000 researchers and staff, the Feinstein Institutes raises the standard of medical innovation through its five institutes of behavioral science, bioelectronic medicine, cancer, health innovations and outcomes, and molecular medicine. We make breakthroughs in genetics, oncology, brain research, mental health, autoimmunity, and are the global scientific leader in bioelectronic medicine – a new field of science that has the potential to revolutionize medicine.

TransCode Therapeutics

Grant in 2023
TransCode Therapeutics, founded in 2016 and based in Boston, Massachusetts, is a biopharmaceutical company dedicated to discovering, developing, and commercializing innovative RNA therapeutics for treating metastatic cancer. Its lead therapeutic candidate targets an RNA molecule that drives metastatic disease across multiple tumor types.

Icahn School of Medicine at Mount Sinai

Grant in 2023
The Mount Sinai School of Medicine in New York, New York, one of the only schools in the nation with a distinctive Department of Medical Education that continually improves the quality of its teaching, offers students a variety of medical academics to shape them into compassionate assistants, professionals and industry leaders. The academics available at Mount Sinai include master's and PhD programs in areas like: * Science and Medicine * Patient Oriented Research Training and Leadership * Biomedical Sciences * Genetic Counseling * Clinical Research Besides its degree-granting programs, Mount Sinai also offers an extensive number of residencies and fellowships, some of which include: * Anesthesiology * Cardiology * Dental Medicine * Emergency Medicine * Hematology and Oncology College life at Mount Sinai is fully-immersed in the medical sciences. All your instruction, provided by medical professionals, will be delivered in a hospital setting, allowing you to familiarize yourself with the many resources and technology used in today's hospitals. Mount Sinai is also home to the Levy Library, which is fully-stocked with myriad medical resources, from journals to professional magazines to textbooks. Since each program has different admissions requirements, please contact Mount Sinai for more information on a program that interests you and your career goals. Tuition assistance is available to students through fellowship programs and Mount Sinai grants and scholarships. For more information federal sources of financial aid, please contact an aid advisor from the school.

Behaivior

Grant in 2023
Behaivior LLC is a digital health company based in Pittsburgh, Pennsylvania, focused on predicting and preventing addiction relapses through innovative technology. Founded in 2017, Behaivior integrates wearable devices with machine learning algorithms to analyze real-time data from various physiological metrics, such as heart rate and skin temperature. The company’s platform, known as Recovery, employs this data to deliver timely interventions tailored to the needs of individuals in recovery. By utilizing a SaaS business model, Behaivior aims to democratize mental health recovery and support, assisting users in maintaining their wellness while enabling care providers to enhance their service delivery. Through its proactive approach, Behaivior seeks to improve mental health outcomes and reduce crisis events associated with addiction.

Albert Einstein College of Medicine

Grant in 2023
Albert Einstein College of Medicine is a research-intensive medical school located in the Bronx, New York, established in 1953. The institution offers a variety of academic programs, including medical degrees and graduate programs in biomedical sciences, along with advanced training in clinical and research fields. Committed to fostering a diverse student body, the college emphasizes both medical education and groundbreaking scientific research. Through partnerships with hospitals and research institutions, Albert Einstein College of Medicine aims to advance healthcare and improve patient outcomes while preparing students to become compassionate physicians and innovative scientific investigators.

University of Pittsburgh

Grant in 2023
Founded in 1787, the University of Pittsburgh is a renowned research university offering professional medical education through its School of Medicine since 1886. It is ranked No. 24 worldwide and No. 9 among U.S. public universities.

Albert Einstein College of Medicine

Grant in 2022
Albert Einstein College of Medicine is a research-intensive medical school located in the Bronx, New York, established in 1953. The institution offers a variety of academic programs, including medical degrees and graduate programs in biomedical sciences, along with advanced training in clinical and research fields. Committed to fostering a diverse student body, the college emphasizes both medical education and groundbreaking scientific research. Through partnerships with hospitals and research institutions, Albert Einstein College of Medicine aims to advance healthcare and improve patient outcomes while preparing students to become compassionate physicians and innovative scientific investigators.

ActuatedMedical

Grant in 2022
Actuated Medical, Inc. is a medical device company based in Bellefonte, Pennsylvania, that focuses on designing, developing, and manufacturing innovative solutions for healthcare. Established in 2006, the company specializes in devices that facilitate occlusion clearing, tissue penetration, and MRI-guided surgical procedures. Their product line includes systems like TubeClear and NG-Clear, which are designed to clear clogs in feeding tubes, as well as devices for controlled tissue penetration, such as the GentleSharp Device and OsteoAccess System. Additionally, Actuated Medical offers MRI-compatible technologies, including direct drive piezoelectric ultrasonic motors that enhance diagnostic and surgical capabilities during imaging procedures. The company's commitment to improving patient care is reflected in their range of minimally invasive instruments and transdermal delivery systems. Actuated Medical was previously known as Piezo Resonance Innovations, Inc. before rebranding in September 2011.

Albert Einstein College of Medicine

Grant in 2022
Albert Einstein College of Medicine is a research-intensive medical school located in the Bronx, New York, established in 1953. The institution offers a variety of academic programs, including medical degrees and graduate programs in biomedical sciences, along with advanced training in clinical and research fields. Committed to fostering a diverse student body, the college emphasizes both medical education and groundbreaking scientific research. Through partnerships with hospitals and research institutions, Albert Einstein College of Medicine aims to advance healthcare and improve patient outcomes while preparing students to become compassionate physicians and innovative scientific investigators.

Feinstein Institute for Medical Research

Grant in 2022
Feinstein Institute For Medical Research is the research arm of Northwell Health, the largest health care provider and private employer in New York State. Home to 50 research labs, 3,000 clinical research studies and 5,000 researchers and staff, the Feinstein Institutes raises the standard of medical innovation through its five institutes of behavioral science, bioelectronic medicine, cancer, health innovations and outcomes, and molecular medicine. We make breakthroughs in genetics, oncology, brain research, mental health, autoimmunity, and are the global scientific leader in bioelectronic medicine – a new field of science that has the potential to revolutionize medicine.

Albert Einstein College of Medicine

Grant in 2022
Albert Einstein College of Medicine is a research-intensive medical school located in the Bronx, New York, established in 1953. The institution offers a variety of academic programs, including medical degrees and graduate programs in biomedical sciences, along with advanced training in clinical and research fields. Committed to fostering a diverse student body, the college emphasizes both medical education and groundbreaking scientific research. Through partnerships with hospitals and research institutions, Albert Einstein College of Medicine aims to advance healthcare and improve patient outcomes while preparing students to become compassionate physicians and innovative scientific investigators.

Worcester Polytechnic Institute

Grant in 2022
Worcester Polytechnic Institute (WPI), located in Worcester, Massachusetts, is a prestigious technological university founded in 1865. Renowned for its commitment to project-based learning, WPI emphasizes practical application of theoretical knowledge to address real-world challenges. The university boasts a distinguished faculty and state-of-the-art research facilities, fostering an environment rich in innovation and collaboration. WPI attracts ambitious students eager to engage in hands-on experiences that prepare them to make meaningful contributions to society. With a strong focus on developing skills that are crucial in today’s dynamic landscape, WPI positions itself as a leader in education and research, dedicated to empowering its students and faculty to achieve excellence.

Babson College

Grant in 2022
Babson College is an independent, not-for-profit institution renowned for its focus on entrepreneurship education. It is accredited by prestigious organizations including the Association to Advance Collegiate Schools of Business and the European Quality Improvement System. The college offers a comprehensive undergraduate program that integrates business and liberal arts, alongside the F.W. Olin Graduate School of Business, which provides highly regarded MBA and MS degrees. Babson also features an Executive Education program tailored for professionals seeking to enhance their skills in a dynamic business landscape. The faculty is distinguished, with a significant majority holding doctoral degrees and possessing extensive real-world experience in various fields. Babson engages in global research initiatives that serve as benchmarks for numerous authorities worldwide, and operates Babson Global, which collaborates with diverse partners to promote entrepreneurship education. Additionally, the Summer Venture Program supports aspiring entrepreneurs through an intensive 10-week experience that includes mentorship, resources, and networking opportunities, culminating in a showcase event that connects participants with the broader startup community.

Oligomerix

Grant in 2022
Founded in 2006, Oligomerix is a biopharmaceutical company dedicated to developing therapeutics for Alzheimer's and related neurodegenerative diseases. It focuses on tau oligomer and tau protease inhibitor programs for small molecule drug discovery, and develops antibody fragments for tau oligomers as biomarkers.

Feinstein Institute for Medical Research

Grant in 2022
Feinstein Institute For Medical Research is the research arm of Northwell Health, the largest health care provider and private employer in New York State. Home to 50 research labs, 3,000 clinical research studies and 5,000 researchers and staff, the Feinstein Institutes raises the standard of medical innovation through its five institutes of behavioral science, bioelectronic medicine, cancer, health innovations and outcomes, and molecular medicine. We make breakthroughs in genetics, oncology, brain research, mental health, autoimmunity, and are the global scientific leader in bioelectronic medicine – a new field of science that has the potential to revolutionize medicine.

Albert Einstein College of Medicine

Grant in 2022
Albert Einstein College of Medicine is a research-intensive medical school located in the Bronx, New York, established in 1953. The institution offers a variety of academic programs, including medical degrees and graduate programs in biomedical sciences, along with advanced training in clinical and research fields. Committed to fostering a diverse student body, the college emphasizes both medical education and groundbreaking scientific research. Through partnerships with hospitals and research institutions, Albert Einstein College of Medicine aims to advance healthcare and improve patient outcomes while preparing students to become compassionate physicians and innovative scientific investigators.

Albert Einstein College of Medicine

Grant in 2022
Albert Einstein College of Medicine is a research-intensive medical school located in the Bronx, New York, established in 1953. The institution offers a variety of academic programs, including medical degrees and graduate programs in biomedical sciences, along with advanced training in clinical and research fields. Committed to fostering a diverse student body, the college emphasizes both medical education and groundbreaking scientific research. Through partnerships with hospitals and research institutions, Albert Einstein College of Medicine aims to advance healthcare and improve patient outcomes while preparing students to become compassionate physicians and innovative scientific investigators.

Simulations Plus

Grant in 2022
Founded in 1996, Simulations Plus develops Absorption, Distribution, Metabolism, Excretion and Toxicity (ADMET) and Physiologically-Based Pharmacokinetic (PBPK) modeling software for the pharmaceutical industry. Its software aids in predicting key endpoints, reducing R&D costs, and supporting better project decisions. With over 60 employees, Simulations Plus serves major pharmaceutical companies and regulatory agencies worldwide.

NYU Langone Health

Grant in 2022
NYU Langone Health is a nonprofit academic medical center located in New York City, recognized for its commitment to patient-centered care, research, and medical education. The organization offers a comprehensive range of healthcare services, diagnosing and treating various conditions, including lung diseases, joint and muscle disorders, neurological disorders, blood disorders, and gastrointestinal issues. As a center of excellence, NYU Langone Health integrates advanced medical practices with innovative research to enhance patient outcomes and contribute to advancements in healthcare.

Weill Cornell Medicine

Grant in 2022
Weill Cornell Medicine is a renowned academic medical center dedicated to excellence in patient care, scientific discovery, and educating future physicians. With over 300 IT professionals supporting more than 10,000 users across its institutions, it offers comprehensive technology services, including infrastructure management, security, networking, software development, and innovative solutions for clinical and research projects.

Epicore Biosystems

Series A in 2022
Epicore Biosystems, Inc. is a Cambridge, Massachusetts-based company that develops and commercializes a proprietary wearable microfluidic sensing platform designed for athletes. Founded in 2017, the company focuses on analyzing small droplets of sweat directly from the skin to measure a range of health and performance metrics. Its technology allows for non-invasive monitoring of sweat biomarkers, skin health, and physiological states in real-time, facilitating personalized management of hydration, nutrition, and overall health. Epicore's innovative platform is grounded in extensive research in microfluidics and soft materials, aiming to enhance athletic performance and health management through accessible and cost-effective solutions.

Mustang Bio

Grant in 2021
Mustang Bio, Inc. is a clinical-stage biopharmaceutical company dedicated to developing innovative cell and gene therapies aimed at curing hematologic cancers, solid tumors, and rare genetic diseases. The company’s pipeline includes gene therapy programs for rare genetic disorders and chimeric antigen receptor (CAR) T cell therapies targeting various malignancies. Notable developments include MB-107, a potential curative gene therapy for X-linked severe combined immunodeficiency, and several CAR T therapies such as MB-102 for acute myeloid leukemia, MB-106 for B-cell lymphomas, and programs targeting glioblastoma and solid tumors like breast and pancreatic cancers. Mustang Bio has established collaborations with institutions such as Nationwide Children’s Hospital and Beth Israel Deaconess Medical Center to advance its research initiatives. Founded in 2015 and headquartered in New York, the company operates as a subsidiary of Fortress Biotech, Inc.

Albert Einstein College of Medicine

Grant in 2021
Albert Einstein College of Medicine is a research-intensive medical school located in the Bronx, New York, established in 1953. The institution offers a variety of academic programs, including medical degrees and graduate programs in biomedical sciences, along with advanced training in clinical and research fields. Committed to fostering a diverse student body, the college emphasizes both medical education and groundbreaking scientific research. Through partnerships with hospitals and research institutions, Albert Einstein College of Medicine aims to advance healthcare and improve patient outcomes while preparing students to become compassionate physicians and innovative scientific investigators.

SeLux Diagnostics

Grant in 2021
SeLux Diagnostics, Inc. is a biotechnology company based in Charlestown, Massachusetts, focused on developing a next-generation phenotyping platform for antibiotic susceptibility testing and diagnostics of infectious diseases. Established in 2014, the company utilizes synthetic amplifier technology to enhance the speed and complexity of antibiotic susceptibility testing, thereby significantly improving patient care. By facilitating the rapid selection of personalized antimicrobial therapies, SeLux aims to transform the management of infectious diseases, ultimately saving lives, reducing hospital stays, and combating the growing issue of antibiotic resistance through more targeted treatments.

Drexel University

Grant in 2021
Founded in 1891, Drexel is a comprehensive global research university ranked among the top 100 in the U.S., with approximately 26,000 students. Known for its leadership in experiential learning through co-op programs and a history of academic technology firsts, Drexel offers over 200 degree programs across 15 colleges and schools. It is committed to being civically engaged, with community partnerships integrated into service and academics.

Feinstein Institute for Medical Research

Grant in 2021
Feinstein Institute For Medical Research is the research arm of Northwell Health, the largest health care provider and private employer in New York State. Home to 50 research labs, 3,000 clinical research studies and 5,000 researchers and staff, the Feinstein Institutes raises the standard of medical innovation through its five institutes of behavioral science, bioelectronic medicine, cancer, health innovations and outcomes, and molecular medicine. We make breakthroughs in genetics, oncology, brain research, mental health, autoimmunity, and are the global scientific leader in bioelectronic medicine – a new field of science that has the potential to revolutionize medicine.

TransCode Therapeutics

Grant in 2021
TransCode Therapeutics, founded in 2016 and based in Boston, Massachusetts, is a biopharmaceutical company dedicated to discovering, developing, and commercializing innovative RNA therapeutics for treating metastatic cancer. Its lead therapeutic candidate targets an RNA molecule that drives metastatic disease across multiple tumor types.

Feinstein Institute for Medical Research

Grant in 2021
Feinstein Institute For Medical Research is the research arm of Northwell Health, the largest health care provider and private employer in New York State. Home to 50 research labs, 3,000 clinical research studies and 5,000 researchers and staff, the Feinstein Institutes raises the standard of medical innovation through its five institutes of behavioral science, bioelectronic medicine, cancer, health innovations and outcomes, and molecular medicine. We make breakthroughs in genetics, oncology, brain research, mental health, autoimmunity, and are the global scientific leader in bioelectronic medicine – a new field of science that has the potential to revolutionize medicine.

Helixbind

Grant in 2021
Helixbind is a biotechnology company based in Worcester, Massachusetts. Founded in 2012, it specializes in developing a pathogen identification platform designed to rapidly detect and identify bloodstream infections directly from whole blood specimens, enabling timely targeted antimicrobial interventions.

CaroGen Corporation

Grant in 2021
CaroGen Corporation is a biopharmaceutical company developing recombinant virus-like vesicles for vaccines against infectious diseases. Its platform technology enables the creation of vaccines targeting hepatitis B, C, influenza, and other viral agents.

CytoAgents

Grant in 2021
CytoAgents is a clinical-stage biotechnology company focused on developing innovative pharmaceutical products for treating life-threatening symptoms associated with Cytokine Release Syndrome (CRS), an overreaction of the immune system causing systemic inflammation.

Soligenix

Grant in 2020
Soligenix, Inc., a late-stage biopharmaceutical company based in Princeton, New Jersey, focuses on developing and commercializing treatments for rare diseases and serious side effects of cancer therapies, where there is an unmet medical need. The company operates through two segments: Specialized BioTherapeutics and Public Health Solutions. The Specialized BioTherapeutics segment develops therapies such as SGX301 for cutaneous T-cell lymphoma, SGX942 for oral mucositis in head and neck cancer, and proprietary formulations of oral beclomethasone for gastrointestinal disorders. The Public Health Solutions segment works on biodefense vaccines and therapeutics, including RiVax, a ricin toxin vaccine, and SGX943, a therapeutic candidate for antibiotic-resistant and emerging infectious diseases.

University of Vermont

Grant in 2020
The University of Vermont (UVM) is a public research university established in 1791, making it one of the oldest universities in the United States. Located in Burlington, Vermont, UVM offers a wide range of academic programs through its various schools and colleges, including business, social sciences, science, and medicine. Notable features of the campus include the historic University Green, the Dudley H. Davis Center, which is recognized for its environmental sustainability, the Fleming Museum of Art, and the Gutterson/Patrick athletic complex. The university's College of Medicine is affiliated with Fletcher Allen Health Care, the largest hospital complex in Vermont. UVM's extensive academic offerings and affiliations contribute to its role as a significant educational institution in the region.

University of Massachusetts Amherst

Grant in 2020
The University of Massachusetts Amherst is a public research and land-grant university that offers undergraduate, master's, and doctoral programs. It serves as the flagship campus of the University of Massachusetts system. The university has multiple academic departments and research facilities that support a range of disciplines.

Albert Einstein College of Medicine

Grant in 2020
Albert Einstein College of Medicine is a research-intensive medical school located in the Bronx, New York, established in 1953. The institution offers a variety of academic programs, including medical degrees and graduate programs in biomedical sciences, along with advanced training in clinical and research fields. Committed to fostering a diverse student body, the college emphasizes both medical education and groundbreaking scientific research. Through partnerships with hospitals and research institutions, Albert Einstein College of Medicine aims to advance healthcare and improve patient outcomes while preparing students to become compassionate physicians and innovative scientific investigators.

Helixbind

Grant in 2020
Helixbind is a biotechnology company based in Worcester, Massachusetts. Founded in 2012, it specializes in developing a pathogen identification platform designed to rapidly detect and identify bloodstream infections directly from whole blood specimens, enabling timely targeted antimicrobial interventions.

CytoAgents

Grant in 2020
CytoAgents is a clinical-stage biotechnology company focused on developing innovative pharmaceutical products for treating life-threatening symptoms associated with Cytokine Release Syndrome (CRS), an overreaction of the immune system causing systemic inflammation.

Akelos

Grant in 2020
Akelos, Inc. is a biopharmaceutical company founded in 2018 and headquartered in New York, New York. The company focuses on developing innovative non-narcotic drugs aimed at treating chronic and neuropathic pain, addressing the pressing issue of the opioid epidemic. Currently, Akelos is advancing two drug candidates through pre-clinical development, which serve as alternatives to traditional opioid therapies. In addition to its internal research efforts, Akelos has established collaborations to further develop and commercialize its novel, non-opioid anti-hyperalgesic drugs. The company's mission is to provide effective treatments for neuropathic pain while mitigating the risks associated with opioid use.

WindGap Medical

Grant in 2020
Founded in 2011, WindGap Medical specializes in the development and manufacturing of compact epinephrine autoinjectors for treating anaphylaxis. Headquartered in Watertown, Massachusetts.

Rutgers University–New Brunswick

Grant in 2019
Rutgers University–New Brunswick serves as the flagship campus of Rutgers, The State University of New Jersey. It is a prominent research university dedicated to providing high-quality education and fostering innovative research across various disciplines. The institution emphasizes a commitment to excellence in teaching and aims to enhance the welfare of local, national, and global communities through its service initiatives. Rutgers University–New Brunswick plays a vital role in advancing knowledge and contributing to societal improvement through its academic programs and research endeavors.

Rutgers University Endowment

Grant in 2019
Rutgers University, established in 1766 and recognized as the eighth-oldest college in the United States, serves as a prominent institution for higher education in New Jersey. As the largest university within the state's university system, Rutgers offers a comprehensive range of academic programs, including over 100 bachelor's, 100 master's, and 80 doctoral and professional degrees across its 175 academic departments and 29 colleges. The university's endowment fund, managed from its New Brunswick campus, serves as a vital financial resource, providing a stable income stream to supplement tuition and state funding. This endowment supports various initiatives, including student aid, innovative teaching programs, pioneering research, and the development of new technologies, thereby reinforcing Rutgers' commitment to academic excellence and community engagement.

POP Biotechnologies

Grant in 2019
POP Biotechnologies, based in Buffalo, New York, is a life sciences company dedicated to enhancing patients' health through innovative nanomedicine solutions. The company focuses on developing targeted therapies for cancer and other serious diseases, utilizing its proprietary nanoparticle-based drug delivery systems activated by near-infrared light. This technology enables precise, controlled release of therapeutic payloads, aiming to improve patient outcomes in oncology and infectious disease treatment.

Thetis Pharmaceuticals

Grant in 2019
Thetis Pharmaceuticals LLC is a biopharmaceutical company based in Branford, Connecticut, founded in 2011. The company focuses on developing immuno-resolving therapeutic solutions aimed at treating inflammatory bowel diseases and other inflammatory conditions. Utilizing its proprietary HEALER technology platform, Thetis Pharmaceuticals creates novel small molecule drugs that leverage the pharmacological properties of lipids to promote tissue regeneration and manage inflammation effectively. The company's research has yielded resolvins, which are potent agonists designed to facilitate inflammation resolution and tissue repair. These therapies aim to help healthcare professionals regulate the body's inflammatory response without compromising immune function, addressing the challenges associated with overactive inflammation in various diseases.

Rutgers School of Dental Medicine (RSDM)

Grant in 2019
On July 1, 2013, the New Jersey Medical and Health Sciences Education Restructuring Act went into effect, integrating Rutgers, The State University of New Jersey, with most of the schools of the University of Medicine and Dentistry of New Jersey (UMDNJ), including New Jersey Dental School.

Hackensack Meridian Health

Grant in 2019
Hackensack Meridian Health is a not-for-profit healthcare organization based in New Jersey that provides a comprehensive range of medical services and life-enhancing care. The organization operates a network that includes ambulatory care centers, surgery centers, home health services, long-term care facilities, and assisted living communities. Additionally, it offers ambulance services, lifesaving air medical transportation, rehabilitation services, urgent care, and fitness and wellness centers. Through its integrated approach, Hackensack Meridian Health aims to deliver innovative research and improve health outcomes for the communities it serves.

Skelmet

Grant in 2019
Founded in 2015, Skelmet specializes in designing and producing custom-fit head-worn products. Utilizing advanced 3D scanning and printing technologies, the company offers bespoke sunglasses tailored to individual facial measurements, ensuring optimal fit and performance for various sports activities.

CaroGen Corporation

Grant in 2019
CaroGen Corporation is a biopharmaceutical company developing recombinant virus-like vesicles for vaccines against infectious diseases. Its platform technology enables the creation of vaccines targeting hepatitis B, C, influenza, and other viral agents.

Rhode Island Hospital

Grant in 2019
Rhode Island Hospital operates as a hospital in Rhode Island. It offers cancer care, cardiac care, clinical coordinating, colorectal care, dental care, diabetes and endocrinology, diagnostic imaging (radiology), education, emergency medicine, medical simulation, mental health, neurosciences, nursing, oncology, orthopedics, pain management, rehabilitation, social work, stroke, surgery, trauma care, and transplantation services. The company also provides breast imaging, pediatric, cardiovascular surgery programs, electrophysiology, endoscopy, and sleep disorder services; and treatment for mood disorders, such as major depression, chronic major depression, and bipolar disorders. In addition, it offers treatment for tumors and vascular malformations in the brain; and mental health services for problem gamblers. Rhode Island Hospital was founded in 1863 and is based in Providence, Rhode Island.

University of Massachusetts Medical School

Grant in 2019
The University of Massachusetts Medical School (UMMS), founded in 1962 and located in Worcester, Massachusetts, is dedicated to providing affordable, high-quality medical education with a focus on increasing the number of primary care physicians in underserved areas. The institution aims to advance health and wellness in diverse communities both locally and globally through its commitment to education, research, healthcare delivery, and public service. Consistently recognized as a leading medical school for primary care education, UMMS plays a vital role in shaping healthcare professionals and addressing public health challenges.

Pennsylvania State University

Grant in 2018
Pennsylvania State University, founded in 1855, is Pennsylvania’s largest public university and the state’s only land‑grant institution. It operates 24 campuses across the Commonwealth, offering a broad range of undergraduate, graduate, and professional programs. The university emphasizes teaching, research, and public service, collaborating with partners to apply knowledge to community needs. Its specialized schools include the College of Medicine, Dickinson School of Law, World Campus, and Pennsylvania College of Technology. Students from around the world enroll, and many transfer from other Penn State campuses to the flagship University Park campus. The university’s governance is overseen by a board of trustees, and its assets are managed to support students, faculty, staff, and the broader community.

University of Vermont

Grant in 2018
The University of Vermont (UVM) is a public research university established in 1791, making it one of the oldest universities in the United States. Located in Burlington, Vermont, UVM offers a wide range of academic programs through its various schools and colleges, including business, social sciences, science, and medicine. Notable features of the campus include the historic University Green, the Dudley H. Davis Center, which is recognized for its environmental sustainability, the Fleming Museum of Art, and the Gutterson/Patrick athletic complex. The university's College of Medicine is affiliated with Fletcher Allen Health Care, the largest hospital complex in Vermont. UVM's extensive academic offerings and affiliations contribute to its role as a significant educational institution in the region.

Quadrant Biosciences

Grant in 2018
Quadrant Biosciences develops epigenetic diagnostic solutions and biomarker technologies for early detection of neurological and developmental disorders, focusing on autism spectrum disorder, concussion, and Parkinson's disease. It advances research through collaborations with academic and medical institutions to discover novel biomarkers and apply RNA analysis in patient diagnostics, potentially informing care during neurological conditions and broader health challenges. Based in Syracuse, New York, the company aims to deliver innovative diagnostics and related care solutions to improve health outcomes.

University of Rhode Island

Grant in 2018
If you reside in the Kingston, Rhode Island area and are looking for an undergraduate or graduate program for academic study, why not check out the University of Rhode Island? Programs available to choose from as a major include the interesting Animal and Veterinary Science, Business Administration, Civil and Environmental Engineering, Geology and Geological Oceanography, Human Development and Family Studies, International Engineering, Journalism, and Nursing, among many others. URI has a festive student life which includes both entertainment events and organizations which can help students get a leg up in the career search. Study abroad programs are offered during the summer and school year. There is also a strong Greek life, Student Senate, dining, and athletic programs. Other services include a counseling center and health services. If you qualify for financial aid like the Centennial and University Scholarships, your entire tuition may be covered. There are also grants and loans that can help cover tuition and other educational expenses. When it comes time to search for a job, the career service center can help students with writing resumes, interview preparation, meeting potential employers, and much more.

Aquinnah Pharmaceuticals

Grant in 2018
Aquinnah Pharmaceuticals, Inc., founded in 2014 and based in Cambridge, Massachusetts, is a pharmaceutical company dedicated to developing therapies for amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. The company focuses on innovative research aimed at modulating neurodegenerative stress granules, which are thought to play a significant role in the pathology of ALS. Through its specialized approach, Aquinnah Pharmaceuticals aims to address critical unmet medical needs in the field of neurodegeneration.

Behaivior

Grant in 2018
Behaivior LLC is a digital health company based in Pittsburgh, Pennsylvania, focused on predicting and preventing addiction relapses through innovative technology. Founded in 2017, Behaivior integrates wearable devices with machine learning algorithms to analyze real-time data from various physiological metrics, such as heart rate and skin temperature. The company’s platform, known as Recovery, employs this data to deliver timely interventions tailored to the needs of individuals in recovery. By utilizing a SaaS business model, Behaivior aims to democratize mental health recovery and support, assisting users in maintaining their wellness while enabling care providers to enhance their service delivery. Through its proactive approach, Behaivior seeks to improve mental health outcomes and reduce crisis events associated with addiction.

Thetis Pharmaceuticals

Grant in 2018
Thetis Pharmaceuticals LLC is a biopharmaceutical company based in Branford, Connecticut, founded in 2011. The company focuses on developing immuno-resolving therapeutic solutions aimed at treating inflammatory bowel diseases and other inflammatory conditions. Utilizing its proprietary HEALER technology platform, Thetis Pharmaceuticals creates novel small molecule drugs that leverage the pharmacological properties of lipids to promote tissue regeneration and manage inflammation effectively. The company's research has yielded resolvins, which are potent agonists designed to facilitate inflammation resolution and tissue repair. These therapies aim to help healthcare professionals regulate the body's inflammatory response without compromising immune function, addressing the challenges associated with overactive inflammation in various diseases.

Envisagenics

Grant in 2018
Envisagenics is a Huntington, New York-based company that develops a predictive analytics and bioinformatics platform to accelerate RNA therapeutics discovery. The cloud-based SpliceCore platform analyzes RNA sequencing data with artificial intelligence to identify splicing errors linked to disease, predict drug targets, and guide the design of RNA-based therapies. By translating transcriptomic insights into actionable targets, Envisagenics aims to reduce the time, cost, and risk of pharmaceutical development and to support partnerships with biopharma organizations. The firm focuses on uncovering RNA splicing alterations and translating them into therapeutic candidates, enabling researchers to validate targets and biomarkers more efficiently. The company originated as a spinout from Cold Spring Harbor Laboratory and emphasizes the use of AI and machine learning to simplify complex biomedical data for therapeutic discovery.

Windtree Therapeutics

Grant in 2018
Windtree Therapeutics is a clinical-stage biotechnology company focused on developing novel surfactant therapies for respiratory diseases. Its proprietary technology platform includes KL4 surfactant, structurally similar to endogenous pulmonary surfactant, and novel drug-delivery technologies enabling noninvasive administration via aerosolization.

Rutgers University Endowment

Grant in 2018
Rutgers University, established in 1766 and recognized as the eighth-oldest college in the United States, serves as a prominent institution for higher education in New Jersey. As the largest university within the state's university system, Rutgers offers a comprehensive range of academic programs, including over 100 bachelor's, 100 master's, and 80 doctoral and professional degrees across its 175 academic departments and 29 colleges. The university's endowment fund, managed from its New Brunswick campus, serves as a vital financial resource, providing a stable income stream to supplement tuition and state funding. This endowment supports various initiatives, including student aid, innovative teaching programs, pioneering research, and the development of new technologies, thereby reinforcing Rutgers' commitment to academic excellence and community engagement.

Epivax Oncology

Grant in 2018
EpiVax Oncology is a biotechnology company focused on developing personalized immunotherapies for cancer treatment. Based in New York, the company specializes in precision cancer mutanome-directed and neo-epitope therapies, utilizing advanced immuno-oncology and neoantigen discovery solutions. EpiVax Oncology's platform relies on optimal neo-epitopes selected through proprietary, validated predictive algorithms to address unmet medical needs that current cancer therapeutic approaches do not adequately cover. The company was established in 2017 with the goal of providing innovative clinical research and development platforms for various types of precision cancer immunotherapies.

PhaseBio Pharmaceuticals

Grant in 2018
PhaseBio Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing novel therapies for cardiopulmonary diseases. Its lead product candidate, PB2452, is a reversal agent for the antiplatelet drug ticagrelor, intended to manage uncontrolled bleeding events or urgent surgeries. PhaseBio is also developing PB1046 for pulmonary arterial hypertension and PB6440 for resistant hypertension.

Vaxess Technologies

Grant in 2017
Vaxess Technologies is a biotechnology company focused on silk biomaterial platforms for vaccine and therapeutic delivery. It develops the MIMIX microneedle patch for transdermal, sustained-release delivery of vaccines and therapies, designed to improve stability and ease of use, including formulations that do not require cold chain storage. The MATRIX formulation and drying platform supports thermostable vaccine, therapeutic, and diagnostic products. The company aims to enable long-term immune responses and easier distribution, including in low-resource settings. Its technology supports oncology and infectious disease applications, including therapies that promote durable anti-tumor immunity and improved treatment outcomes. Founded in 2011 and based in Boston, the company positions its platforms to enable stable, targeted delivery and potentially reduce treatment burden for patients.

Thetis Pharmaceuticals

Grant in 2017
Thetis Pharmaceuticals LLC is a biopharmaceutical company based in Branford, Connecticut, founded in 2011. The company focuses on developing immuno-resolving therapeutic solutions aimed at treating inflammatory bowel diseases and other inflammatory conditions. Utilizing its proprietary HEALER technology platform, Thetis Pharmaceuticals creates novel small molecule drugs that leverage the pharmacological properties of lipids to promote tissue regeneration and manage inflammation effectively. The company's research has yielded resolvins, which are potent agonists designed to facilitate inflammation resolution and tissue repair. These therapies aim to help healthcare professionals regulate the body's inflammatory response without compromising immune function, addressing the challenges associated with overactive inflammation in various diseases.

The Jackson Laboratory

Grant in 2017
The Jackson Laboratory, established in 1929 and headquartered in Bar Harbor, Maine, with a facility in California, specializes in mammalian genetics research. It provides international laboratories with scientific services and genetic resources, while also educating students through courses, internships, and collaborative programs. The company's primary focus is discovering the genetic basis for preventing, treating, and curing human diseases across various areas such as cancers, immunology, metabolic diseases, and neurobiology. Additionally, it offers comprehensive mouse breeding and research services tailored to the mouse-based biomedical research community, including breeding management, cryopreservation, phenotyping, and study-ready induced models.

Soligenix

Grant in 2017
Soligenix, Inc., a late-stage biopharmaceutical company based in Princeton, New Jersey, focuses on developing and commercializing treatments for rare diseases and serious side effects of cancer therapies, where there is an unmet medical need. The company operates through two segments: Specialized BioTherapeutics and Public Health Solutions. The Specialized BioTherapeutics segment develops therapies such as SGX301 for cutaneous T-cell lymphoma, SGX942 for oral mucositis in head and neck cancer, and proprietary formulations of oral beclomethasone for gastrointestinal disorders. The Public Health Solutions segment works on biodefense vaccines and therapeutics, including RiVax, a ricin toxin vaccine, and SGX943, a therapeutic candidate for antibiotic-resistant and emerging infectious diseases.

Novo Biosciences

Grant in 2017
Novo Biosciences, Inc. is a biotechnology company founded in 2013 and based in Bar Harbor, Maine. The company specializes in the development of small molecule therapies aimed at reversing the damage caused by heart attacks. Its innovative drugs activate dormant genetic mechanisms that promote self-repair and tissue regeneration, allowing both humans and animals to heal more effectively. By harnessing these natural processes, Novo Biosciences seeks to improve health outcomes for patients suffering from life-threatening cardiac conditions.

Mobile Sense Technologies

Grant in 2017
Mobile Sense Technologies, Inc. specializes in the development of innovative wearable wireless sensor bands for cardiac monitoring. Its primary product, SensBand, is designed to be worn on the arm or wrist and enables automatic monitoring, detection, and reporting of dangerous heart arrhythmias directly to patients and their healthcare providers. Founded in 2016 and based in Farmington, Connecticut, the company has invested significant resources into creating a platform for differentiated wearables. The technology includes non-adhesive, wireless, and waterproof sensors that provide continuous ECG and PPG recordings, allowing for 24/7 monitoring and classification of heart conditions. Mobile Sense Technologies aims to transform the traditional diagnostic market by utilizing advanced wearables that facilitate long-term management of cardiac health.

Maine Medical Center

Grant in 2017
Maine Medical Center is a 637 licensed-bed teaching hospital located at 22 Bramhall Street in Portland, Maine

The Jackson Laboratory

Grant in 2017
The Jackson Laboratory, established in 1929 and headquartered in Bar Harbor, Maine, with a facility in California, specializes in mammalian genetics research. It provides international laboratories with scientific services and genetic resources, while also educating students through courses, internships, and collaborative programs. The company's primary focus is discovering the genetic basis for preventing, treating, and curing human diseases across various areas such as cancers, immunology, metabolic diseases, and neurobiology. Additionally, it offers comprehensive mouse breeding and research services tailored to the mouse-based biomedical research community, including breeding management, cryopreservation, phenotyping, and study-ready induced models.

Helixbind

Grant in 2017
Helixbind is a biotechnology company based in Worcester, Massachusetts. Founded in 2012, it specializes in developing a pathogen identification platform designed to rapidly detect and identify bloodstream infections directly from whole blood specimens, enabling timely targeted antimicrobial interventions.

Emulate

Grant in 2017
Emulate is a biotechnology company that develops organ-on-a-chip human emulation technology to model how diseases, medicines, chemicals, and foods affect human health. Its platform includes lung, intestinal, liver, and skin organ chips that reproduce normal biology and disease states, enabling human-relevant insights beyond traditional cell culture or animal models. The company also provides drug development tools and instrumentation software to support research and development workflows for researchers across biotechnology, pharmaceutical, consumer health, cosmetics, chemical, food, and agrochemical sectors, as well as government agencies and academic institutions. Founded in 2013 and headquartered in Boston, Emulate aims to accelerate understanding of human biology and improve human health outcomes.

Aldatu Biosciences

Grant in 2017
Founded in 2014, Aldatu Biosciences specializes in adaptive PCR diagnostics for global health. Its proprietary PANDAA technology enables detection of highly variable genomic regions, empowering healthcare providers to improve patient outcomes and reduce costs, particularly in HIV care.

Coriell Institute for Medical Research

Grant in 2016
Coriell Institute for Medical Research, founded in 1953 and based in Camden, New Jersey, is an independent non-profit research center dedicated to the study of the human genome. Expert staff and pioneering programs in the fields of personalized medicine, cell biology, cytogenetics, genotyping, and biobanking drive Their mission. The emerging field of personalized medicine draws upon a person’s genomic information to tailor treatments and prescription drug dosing to optimize health outcomes. The Coriell Personalized Medicine Collaborative (CPMC) research study is seeking to understand the usefulness of genetic risk and pharmacogenomics in clinical decision-making and healthcare management.

EpiVax

Grant in 2016
EpiVax, Inc. is a biotechnology company specializing in computational immunology tools. Established in 1998 and based in Providence, Rhode Island, EpiVax focuses on developing innovative solutions to assess and mitigate immunogenic risks associated with protein therapeutics. The company offers a range of services, including interactive protein screening, immunogenicity predictions for antibody candidates, and informatics tools for evaluating host cell protein contaminants. Additionally, EpiVax provides deimmunization services to reduce immunogenicity in therapeutic proteins and develops epitope-based vaccines targeting diseases such as smallpox, tularemia, tuberculosis, and influenza. Its advanced platform also facilitates the design of epitope-driven vaccines and includes capabilities for lab-based immunogenicity assays and T cell assays. Through its comprehensive analytical capabilities, EpiVax aims to enhance the development of immunotherapeutics while minimizing side effects for patients.

SAb Biotherapeutics

Grant in 2016
SAB Biotherapeutics is a clinical-stage biopharmaceutical company established in 2014, headquartered in Sioux Falls, South Dakota with additional offices in Cambridge, Massachusetts. The company specializes in developing immunotherapies using its proprietary DiversitAb platform, which employs transchromosomic cattle to produce large quantities of targeted human polyclonal antibodies without relying on human plasma or serum. SAB's pipeline includes therapies for conditions such as Type 1 diabetes (SAB-142), seasonal influenza (SAB-176), and Middle East Respiratory Syndrome Coronavirus (MERS-CoV, SAB-301).

Helixbind

Grant in 2016
Helixbind is a biotechnology company based in Worcester, Massachusetts. Founded in 2012, it specializes in developing a pathogen identification platform designed to rapidly detect and identify bloodstream infections directly from whole blood specimens, enabling timely targeted antimicrobial interventions.

Embera NeuroTherapeutics

Grant in 2016
Embera NeuroTherapeutics, Inc. is a pharmaceutical company based in Sudbury, Massachusetts, founded in 2005. The company is focused on developing innovative treatments for smoking cessation, cocaine dependence, and other addictions, an area where effective drug therapies are limited or nonexistent. Embera's flagship product, EMB-001, combines the benzodiazepine oxazepam with metyrapone, a cortisol synthesis inhibitor, to target the stress response system and specific brain functions linked to cravings and relapse. This dual-action approach aims to modulate various stress-related pathways, thereby reducing the cravings that drive addictive behaviors. By addressing the underlying mechanisms of addiction, Embera NeuroTherapeutics seeks to offer a more effective solution for individuals struggling with these disorders.

Cyteir Therapeutics

Grant in 2016
Cyteir Therapeutics, Inc. is a clinical-stage biotechnology company dedicated to developing innovative therapies based on DNA repair biology for cancer treatment and synthetic lethality in autoimmune diseases. Founded in 2012 and headquartered in Lexington, Massachusetts, the company focuses on precision targeting of critical DNA repair factors to induce self-destruction in diseased cells through an overload of DNA damage. Cyteir employs an integrated drug development platform that addresses the imbalance between DNA damage and repair, resulting in a pipeline of small molecule therapeutics aimed at various disease states, including hematological malignancies, solid tumors, and chronic autoimmune disorders. Its lead compound, CYT-0851, is an oral investigational drug designed to inhibit RAD51-mediated homologous recombination, targeting specific vulnerabilities in cancer cells.

Soterix Medical

Grant in 2016
Soterix Medical develops medical devices and accessories for neuromodulation and brain stimulation, including transcranial electrical stimulation and high-definition transcranial electrical stimulation, to provide safe and effective neuromodulation options for clinicians and patients. Based in New York, the company focuses on user-friendly technology that supports clinical and research applications in brain stimulation.
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