The National Institutes of Health (NIH) is a leading biomedical research facility in the United States, operating under the Department of Health and Human Services. Established in 1887 and based in Bethesda, Maryland, NIH is the primary agency responsible for biomedical and health-related research in the country. It comprises 27 separate institutes and centers, each focusing on different disciplines within biomedical science. NIH conducts its own scientific research through the Intramural Research Program and provides significant funding for research at external institutions via the Extramural Research Program. With a workforce that includes 1,200 principal investigators and over 4,000 postdoctoral fellows, NIH has been instrumental in major medical breakthroughs, such as the development of vaccines for hepatitis and human papillomavirus, as well as the discovery of treatments for various health conditions. As the world's largest source of medical research funding, NIH continues to advance scientific knowledge and contribute to public health improvements.
GreenMark Biomedical Inc. is a healthcare company focused on developing minimally invasive technologies utilizing biopolymer nanoparticles derived from natural starch. Founded in 2016 and based in East Lansing, Michigan, with a laboratory in Ann Arbor, the company aims to enhance diagnostic and treatment capabilities in dentistry and oncology. GreenMark offers a mouth rinse product that highlights cavities and early-stage lesions, allowing dentists to accurately assess dental issues using standard dental curing lamps. Additionally, the company is working on medical applications that target anti-cancer drug delivery, facilitating site-specific treatments. Through its innovative approach, GreenMark Biomedical seeks to provide effective health-based solutions that improve patient care.
University of Michigan
Grant in 2024
The University of Michigan, one of the largest universities in the Midwest, offers a diverse array of academic programs that attract over 40,000 undergraduate, graduate, and professional students. Its renowned schools include the Stephen Ross School of Business, the College of Engineering, and prominent law and medical schools. The university also has a vibrant arts scene, highlighted by its Musical Theatre program and the annual Ann Arbor Film Festival, which draws filmmakers globally. In addition to its educational endeavors, the University of Michigan actively manages a significant endowment, investing in alternative assets such as private equity, real estate, and infrastructure to support its mission and enhance its resources. The institution consistently ranks highly in national assessments, reflecting its commitment to academic excellence and innovation.
Michigan State University
Grant in 2023
Michigan State University, founded in 1855 and located in East Lansing, Michigan, is a comprehensive educational institution offering a wide range of undergraduate, graduate, and research programs across various fields, including business, humanities, science and technology, and public affairs. Its academic structure comprises several colleges, including the Eli Broad College of Business and the Eli Broad Graduate School of Management, among others. In addition to its educational mission, Michigan State University manages an endowment fund with $200 million in assets, employing alternative investment strategies such as buyouts, hedge funds, and venture capital. The endowment aims for a net internal rate of return of 10%, with allocations of up to 11% of total assets dedicated to alternative investments. This fund has been operational since 1988, highlighting the university's commitment to financial stewardship in support of its educational objectives.
Eastern Michigan University Foundation
Grant in 2022
Eastern Michigan University, located in Ypsilanti, Michigan, is a comprehensive educational institution established in 1849. It offers a wide range of undergraduate and graduate programs, including unique and nationally recognized majors such as Aviation Flight Technology, Music Therapy, and Occupational Therapy. The university's academic offerings span various fields, including the arts, sciences, social sciences, and business management. Eastern Michigan is known for its commitment to quality education, with several programs, such as Special Education and Forensics, receiving national acclaim. The university fosters a vibrant campus life with over 200 student organizations. To enroll, first-time freshmen must submit an application along with academic transcripts and standardized test scores, typically requiring a minimum GPA of 2.0. The Eastern Michigan University Foundation, established in 1989, manages an endowment to provide financial support for students and educational programs, enhancing the overall academic experience at the university.
Genomenon
Grant in 2022
Genomenon, Inc. is a software development company based in Ann Arbor, Michigan, that specializes in tools for genetic diagnosis and discovery. Founded in 2014, it provides a suite of diagnostic and discovery solutions that enable physicians, researchers, and pharmaceutical companies to rapidly and accurately identify disease-causing variants from genomic sequencing data. The company’s flagship product, GENOMENON, automates the analysis of next-generation sequencing data, thereby enhancing decision-making processes in clinical settings and accelerating discoveries in genomics. With its focus on improving cancer diagnosis and treatment, Genomenon aims to support better patient outcomes through its innovative software solutions.
Michigan State University
Grant in 2021
Michigan State University, founded in 1855 and located in East Lansing, Michigan, is a comprehensive educational institution offering a wide range of undergraduate, graduate, and research programs across various fields, including business, humanities, science and technology, and public affairs. Its academic structure comprises several colleges, including the Eli Broad College of Business and the Eli Broad Graduate School of Management, among others. In addition to its educational mission, Michigan State University manages an endowment fund with $200 million in assets, employing alternative investment strategies such as buyouts, hedge funds, and venture capital. The endowment aims for a net internal rate of return of 10%, with allocations of up to 11% of total assets dedicated to alternative investments. This fund has been operational since 1988, highlighting the university's commitment to financial stewardship in support of its educational objectives.
Ocuphire Pharma
Grant in 2020
Ocuphire Pharma, Inc. is a clinical-stage biopharmaceutical company based in Farmington Hills, Michigan, dedicated to developing and commercializing therapies for various ophthalmic disorders. The company's primary focus is on innovative treatment options for front and back of the eye conditions, with its lead product candidate, Nyxol eye drops, currently in Phase 3 clinical development. Nyxol is a once-daily, preservative-free formulation aimed at addressing issues such as dim light or night vision disturbances, pharmacologically-induced mydriasis, and presbyopia. Additionally, Ocuphire is advancing another candidate, APX3330, a twice-daily oral tablet, which is entering Phase 2 clinical trials to target diabetic retinopathy and diabetic macular edema by inhibiting angiogenesis and inflammation. The company also seeks to explore opportunities for acquiring additional ophthalmic assets and forming strategic partnerships for global commercialization.
Xoran Technologies
Grant in 2019
Xoran Technologies, LLC is a manufacturer of advanced computed tomography (CT) imaging solutions designed for immediate diagnosis at the point of care. Based in Ann Arbor, Michigan, the company provides a range of products, including the MiniCAT for high-resolution imaging of sinuses and temporal bones, and the Xoran xCAT, a mobile cone beam CT system that captures high-resolution three-dimensional images. Xoran Technologies also offers LuminX digital radiography systems, including overhead robotic suites and various floor-mounted and mobile options. Founded in 2001, the company is dedicated to enhancing patient care by delivering innovative imaging technologies that facilitate accurate diagnoses while minimizing radiation exposure.
University of Michigan
Grant in 2017
The University of Michigan, one of the largest universities in the Midwest, offers a diverse array of academic programs that attract over 40,000 undergraduate, graduate, and professional students. Its renowned schools include the Stephen Ross School of Business, the College of Engineering, and prominent law and medical schools. The university also has a vibrant arts scene, highlighted by its Musical Theatre program and the annual Ann Arbor Film Festival, which draws filmmakers globally. In addition to its educational endeavors, the University of Michigan actively manages a significant endowment, investing in alternative assets such as private equity, real estate, and infrastructure to support its mission and enhance its resources. The institution consistently ranks highly in national assessments, reflecting its commitment to academic excellence and innovation.
Genomenon
Grant in 2017
Genomenon, Inc. is a software development company based in Ann Arbor, Michigan, that specializes in tools for genetic diagnosis and discovery. Founded in 2014, it provides a suite of diagnostic and discovery solutions that enable physicians, researchers, and pharmaceutical companies to rapidly and accurately identify disease-causing variants from genomic sequencing data. The company’s flagship product, GENOMENON, automates the analysis of next-generation sequencing data, thereby enhancing decision-making processes in clinical settings and accelerating discoveries in genomics. With its focus on improving cancer diagnosis and treatment, Genomenon aims to support better patient outcomes through its innovative software solutions.
ONL Therapeutics
Grant in 2017
ONL Therapeutics is a biopharmaceutical company focused on developing innovative therapeutics to protect and improve vision in patients with retinal diseases and conditions. Founded in 2006 and headquartered in Ann Arbor, Michigan, the company specializes in creating photoreceptor protective agents that target the FAS apoptotic pathway. Its drug programs aim to safeguard photoreceptors, thereby enhancing outcomes for patients undergoing surgeries related to retinal detachment and other serious vision-threatening issues. Through its research and development efforts, ONL Therapeutics seeks to provide effective solutions for preserving sight and improving the quality of life for individuals affected by these conditions.
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