GreenMark Biomedical
Grant in 2025
GreenMark Biomedical Inc. is a minimally invasive healthcare company focused on developing innovative technologies utilizing biopolymer nanoparticles derived from natural starch. Founded in 2016 and based in East Lansing, Michigan, with a laboratory in Ann Arbor, the company specializes in dental and medical applications. Its dental technologies include a mouth rinse product that illuminates cavities and early-stage lesions, allowing dentists to accurately diagnose and treat tooth decay. Additionally, GreenMark's medical technologies are designed for targeted delivery of anti-cancer drugs, enhancing treatment precision. The company aims to provide health benefits through its advanced nanoparticle-based solutions, promoting less invasive and more effective healthcare practices.
University of Michigan
Grant in 2024
The University of Michigan, one of the largest universities in the Midwest, offers a diverse array of academic programs that attract over 40,000 undergraduate, graduate, and professional students. Its renowned schools include the Stephen Ross School of Business, the College of Engineering, and prominent law and medical schools. The university also has a vibrant arts scene, highlighted by its Musical Theatre program and the annual Ann Arbor Film Festival, which draws filmmakers globally. In addition to its educational endeavors, the University of Michigan actively manages a significant endowment, investing in alternative assets such as private equity, real estate, and infrastructure to support its mission and enhance its resources. The institution consistently ranks highly in national assessments, reflecting its commitment to academic excellence and innovation.
Rosalind Franklin University of Medicine and Science
Grant in 2024
Rosalind Franklin University of Medicine and Science, established in 1912, is a North Chicago, Illinois-based institution dedicated to educating future health science leaders. It comprises five schools offering degrees such as Doctor of Medicine, Doctor of Podiatric Medicine, Nurse Anesthesia, Physical Therapy, and Physician's Assistant. The university fosters research and provides opportunities for students to engage in it, both on campus and through partnerships with nearby institutions. It aims to enrich students' lives professionally, mentally, and socially through various organizations and activities. Admission requirements vary by school but generally seek students with a strong scientific background and leadership skills. The university offers financial aid to eligible students who demonstrate need.
Cincinnati Children’s
Grant in 2024
Cincinnati Children’s Hospital Medical Center is a leading institution dedicated to improving child health, attracting patients and families both regionally and internationally. Recognized for its expertise, the hospital serves as a referral center for complex surgical procedures and treatments for rare pediatric diseases. The center is committed to advancing pediatric medicine by discovering innovative and effective treatment methods, solidifying its reputation as one of the foremost facilities for pediatric care globally.
Lamassu Pharma
Grant in 2024
Lamassu Pharma is a biotech startup developing small-molecule therapies for severe acute pancreatitis, with a lead candidate developed at Mayo Clinic that has shown strong preclinical results in reducing mortality and morbidity. The company is advancing this compound through safety testing in preparation for definitive clinical trials, aiming to deliver life-saving treatments to patients. In addition, Lamassu develops other small-molecule therapeutics targeting urgent medical needs, including potential cancer treatments, pursuing multiple candidates through clinical development. The organization emphasizes a patient-centric, evidence-based research approach to accelerate translation of science into therapies for unmet medical needs.
Rhaeos is a pioneering company that has developed the world's first wearable shunt monitor, designed to enhance the quality of care for patients with hydrocephalus. Utilizing a novel thermal biosensor, Rhaeos addresses a critical clinical need by offering noninvasive, wireless patches that detect fluid flow in various bodily systems, including blood, lymph, and cerebrospinal fluid. This innovative technology enables timely treatment for chronic medical conditions, particularly in the field of neurosurgery. Founded through collaborative efforts at Northwestern University, Rhaeos exemplifies a multidisciplinary approach, integrating expertise from engineering, medicine, and management to advance patient care.
Neurodon Corporation is a biopharmaceutical company focused on discovering and developing disease-modifying therapeutic candidates for intractable diseases. Established in 2019 and headquartered in Crown Point, Indiana, Neurodon specializes in molecular therapies that address endoplasmic reticulum (ER) stress, a significant factor in cell dysfunction and death. The company's innovative approach aims to restore calcium homeostasis through first-in-class modulators, addressing conditions such as Alzheimer's disease, Parkinson's disease, Huntington's disease, diabetes, and other rare diseases. Neurodon has made significant progress, with two candidates currently in IND-enabling studies and plans to enter clinical trials in 2025. The company has raised over $11 million through various funding sources, including state and federal grants, partnerships, and angel investments, and is actively seeking additional funding to support its first human studies for diabetes and rare disease programs.
University of Minnesota Medical School
Grant in 2023
University of Minnesota Medical School educates students, provides patient care, and performs biomedical and clinical research. UMN Medical School offers medical, graduate, and undergraduate degree programs, as well as continuing professional development.
The Medical School has two campuses based in the Twin Cities and Duluth, Minnesota. The Twin Cities campus is an interdisciplinary research center. The Duluth campus educates 130 first and second-year medical students committed to practicing in rural or American Indian communities.
Medical College of Wisconsin
Grant in 2023
The Medical College of Wisconsin, established in 1893 and located in Milwaukee, is dedicated to advancing education and research in the health sciences. It prepares the next generation of physicians, scientists, and healthcare professionals through a variety of graduate programs, including bioethics, healthcare technologies management, and pharmacology. The college employs a unique Discovery Curriculum that emphasizes personalized education, combining classroom instruction with hands-on clinical experiences guided by experienced faculty and medical technicians. The Student Teaching Assessment Resource Center (STAR) provides a platform for students and professionals to hone their clinical skills using advanced medical simulators. The college also offers financial aid opportunities and reduced tuition for Wisconsin residents. Its mission encompasses not only education but also the discovery and application of new biomedical knowledge, aiming to enhance community health and deliver high-quality patient care.
Avera McKennan Hospital School of Radiologic Technology
Grant in 2023
The Avera McKennan Hospital School of Radiologic Technology in Sioux Falls, South Dakota, offers a 24 month Radiologic Technology program that is rooted in the Roman Catholic healing ministry of the Gospel. Avera McKennan strives to produce students who uphold Christian values throughout their medical career.
The school's academics are designed to prepare students to take the American Registry of Radiologic Technology's certification exam. To be qualified to sit for the exam, students must have earned an associate's degrees. Since this degree does not have to be in Radiologic Technology, Avera McKennan participates with a number of colleges and universities throughout South Dakota to help its students earn their credentials to take the exam.
Your instruction will be delivered through lectures, demonstrations and guided clinical experiences at the Sioux Falls Veterans Administration Center. Since your education will be completed in real hospitals, you will gain valuable work experience during your college life to prepare you for the demands of the career.
Avera McKennan's coursework emphasizes the healing power of Christ's ministry. Students are expected to embody these qualities and be willing to dedicate their lives to helping others.
To apply, students must submit an application, high school or college transcript, ACT scores and three letters of recommendation. Admissions are determined based on upon an applicant's character and willingness to succeed.
For information on the availability of financial aid and other tuition assistance programs, please contact Avera McKennan.
Michigan State University
Grant in 2023
Michigan State University, founded in 1855 and located in East Lansing, Michigan, is a comprehensive educational institution offering a wide range of undergraduate, graduate, and research programs across various fields, including business, humanities, science and technology, and public affairs. Its academic structure comprises several colleges, including the Eli Broad College of Business and the Eli Broad Graduate School of Management, among others. In addition to its educational mission, Michigan State University manages an endowment fund with $200 million in assets, employing alternative investment strategies such as buyouts, hedge funds, and venture capital. The endowment aims for a net internal rate of return of 10%, with allocations of up to 11% of total assets dedicated to alternative investments. This fund has been operational since 1988, highlighting the university's commitment to financial stewardship in support of its educational objectives.
Washington University School Of Medicine
Grant in 2023
Washington University School of Medicine is the medical school of Washington University in St. Louis.A leader in medical research, teaching and patient care, Washington University School of Medicine is currently ranked fourth in the nation by U.S. News & World Report.
The School’s 2,100 employed and volunteer faculty physicians and clinicians -- known as Washington University Physicians -- are also medical staff members of Barnes-Jewish and St. Louis Children’s hospitals. The clinical practice group provides care to more than 430,000 children and adults at 49 clinical sites annually.
Together, the institutions located on the Washington University Medical Center campus employ more than 21,000 clinicians, scientists, residents, fellows, administrators and support staff.
The Indiana CTSI
Grant in 2023
The Indiana CTSI is dedicated to leveraging and strengthening the state’s life sciences community to achieve better health for people in Indiana.Leadership and staff at the Indiana CTSI are working to develop the best processes and resources to enable the efficient translation of scientific discoveries to patient care.Indiana CTSI programs and partnerships are designed to educate, attract and retain top research talent in the state for generations to come.
Cleveland Clinic
Grant in 2023
Cleveland Clinic is a non-profit academic medical center that integrates clinical and hospital care with research and education. Its mission is to provide better care for the sick, investigate medical problems, and advance the education of those who serve.
Case Western Reserve University
Grant in 2022
Case Western Reserve University (CWRU) is a private research university located in Cleveland's University Circle. Established in 1843, it comprises various schools including Medicine, Law, Engineering, Arts and Sciences, Nursing, Social Sciences, Dental Medicine, Management, and Mandel School of Applied Social Sciences. CWRU is renowned for its biomedical discoveries, medical education, and top-ranked programs such as international law, health law, and intellectual property law. It offers practical experiences like real-client work and full-time practice experiences to students across various disciplines. The university is accredited by several professional associations and holds membership in the Association of American Universities.
Cellular Logistics
Grant in 2022
Cellular Logistics, Inc. is a biotechnology company founded in 2016 and headquartered in Sun Prairie, Wisconsin. The company specializes in the development of an acellular biomaterial aimed at enhancing cell survival rates and retention in regenerative medicine therapies. This innovative biomaterial serves as a stand-alone therapeutic for applications related to cardiac and tissue vascularization and offers an effective cell delivery mechanism for regenerative treatments. By improving post-injection cell retention, Cellular Logistics aims to enhance patient outcomes in regenerative medicine.
Indiana University School of Medicine
Grant in 2022
The Indiana University School of Medicine is the largest medical school in the United States. The IU School of Medicine, which is made up of five fundamental science departments and twenty clinical departments, provides superior training for students interested in pursuing a medical degree. The school launched a new medical education curriculum with the Class of 2020 that better represents the modern U.S. health care environment and delivery methods, preparing students to practice medicine in a team-based, multidisciplinary setting.
Case Western Reserve University
Grant in 2022
Case Western Reserve University (CWRU) is a private research university located in Cleveland's University Circle. Established in 1843, it comprises various schools including Medicine, Law, Engineering, Arts and Sciences, Nursing, Social Sciences, Dental Medicine, Management, and Mandel School of Applied Social Sciences. CWRU is renowned for its biomedical discoveries, medical education, and top-ranked programs such as international law, health law, and intellectual property law. It offers practical experiences like real-client work and full-time practice experiences to students across various disciplines. The university is accredited by several professional associations and holds membership in the Association of American Universities.
Cleveland Clinic
Grant in 2022
Cleveland Clinic is a non-profit academic medical center that integrates clinical and hospital care with research and education. Its mission is to provide better care for the sick, investigate medical problems, and advance the education of those who serve.
Eastern Michigan University
Grant in 2022
Founded in 1849, Eastern Michigan University is a public institution offering comprehensive academic programs. It provides over 200 undergraduate and graduate degrees across various fields such as arts, sciences, business, education, health professions, and more. The university is known for its unique majors like Arts Management and Music Therapy, and its programs in Special Education and Forensics are nationally recognized.
Genomenon, Inc. is a software development company based in Ann Arbor, Michigan, that specializes in tools for genetic diagnosis and discovery. Founded in 2014, it provides a suite of diagnostic and discovery solutions that enable physicians, researchers, and pharmaceutical companies to rapidly and accurately identify disease-causing variants from genomic sequencing data. The company’s flagship product, GENOMENON, automates the analysis of next-generation sequencing data, thereby enhancing decision-making processes in clinical settings and accelerating discoveries in genomics. With its focus on improving cancer diagnosis and treatment, Genomenon aims to support better patient outcomes through its innovative software solutions.
Michigan State University
Grant in 2021
Michigan State University, founded in 1855 and located in East Lansing, Michigan, is a comprehensive educational institution offering a wide range of undergraduate, graduate, and research programs across various fields, including business, humanities, science and technology, and public affairs. Its academic structure comprises several colleges, including the Eli Broad College of Business and the Eli Broad Graduate School of Management, among others. In addition to its educational mission, Michigan State University manages an endowment fund with $200 million in assets, employing alternative investment strategies such as buyouts, hedge funds, and venture capital. The endowment aims for a net internal rate of return of 10%, with allocations of up to 11% of total assets dedicated to alternative investments. This fund has been operational since 1988, highlighting the university's commitment to financial stewardship in support of its educational objectives.
Cytonus Therapeutics
Grant in 2021
Cytonus Therapeutics, Inc. is a biotechnology company founded in 2018 and located in Columbus, Ohio. The company specializes in developing immune-oncology and gene therapies aimed at addressing devastating and rare diseases. Cytonus employs a synthetic biology approach through its proprietary Cargocyte technology, which enables precision delivery of therapeutics and in vivo production of innovative treatments. By integrating AI-driven drug discovery methods, Cytonus is focused on creating first-in-class therapeutics to treat immune-related disorders effectively.
Northwestern University
Grant in 2021
Northwestern University, established in 1851, is a comprehensive research university offering over 120 undergraduate programs and more than 140 graduate and professional degrees across its 12 schools and colleges. It provides educational services, including internship opportunities, career guidance, financial aid options such as loans, grants, and scholarships, and exam certification resources to its approximately 8,500 undergraduate students and 9,000 graduate/professional students. The university is renowned for its law school, founded in 1859, which offers Juris Doctor (J.D.) degrees and various master's programs, along with executive education and clinical legal education opportunities. Northwestern University is headquartered in Evanston, Illinois, with additional campuses in Chicago and Doha, Qatar.
Cytonus Therapeutics
Grant in 2021
Cytonus Therapeutics, Inc. is a biotechnology company founded in 2018 and located in Columbus, Ohio. The company specializes in developing immune-oncology and gene therapies aimed at addressing devastating and rare diseases. Cytonus employs a synthetic biology approach through its proprietary Cargocyte technology, which enables precision delivery of therapeutics and in vivo production of innovative treatments. By integrating AI-driven drug discovery methods, Cytonus is focused on creating first-in-class therapeutics to treat immune-related disorders effectively.
Cardialen, Inc. is a medical device company based in Minneapolis, Minnesota, that specializes in developing innovative therapies for heart arrhythmias, particularly atrial fibrillation. Founded in 2008, the company focuses on creating implantable devices that provide low-energy, pain-free cardioversion therapies to restore normal heart rhythm. These devices utilize a proprietary technology that delivers a sequential series of low-voltage pulses to effectively address atrial fibrillation and other related conditions, such as rapid ventricular tachycardia and ventricular fibrillation, while minimizing patient discomfort and protecting heart tissue from damage. By targeting significant unmet medical needs, Cardialen aims to improve the quality of life for individuals suffering from these heart conditions.
Indiana University Bloomington
Grant in 2020
Founded in 1820, Indiana University Bloomington is a public research-intensive university committed to liberal arts and sciences education. It offers professional, medical, and technological programs, aiming to create, disseminate, preserve, and apply knowledge through cutting-edge research, scholarship, and creative activity.
Ocuphire Pharma
Grant in 2020
Ocuphire Pharma is a clinical-stage biopharmaceutical company focused on developing and commercializing therapies for various ophthalmic disorders. Its lead product candidate, Nyxol eye drops, is a once-daily preservative-free formulation of phentolamine mesylate aimed at reducing pupil size for indications such as night vision disturbances, glaucoma, pharmacologically-induced mydriasis, and presbyopia.
Cytonus Therapeutics
Grant in 2020
Cytonus Therapeutics, Inc. is a biotechnology company founded in 2018 and located in Columbus, Ohio. The company specializes in developing immune-oncology and gene therapies aimed at addressing devastating and rare diseases. Cytonus employs a synthetic biology approach through its proprietary Cargocyte technology, which enables precision delivery of therapeutics and in vivo production of innovative treatments. By integrating AI-driven drug discovery methods, Cytonus is focused on creating first-in-class therapeutics to treat immune-related disorders effectively.
Cytonus Therapeutics
Grant in 2020
Cytonus Therapeutics, Inc. is a biotechnology company founded in 2018 and located in Columbus, Ohio. The company specializes in developing immune-oncology and gene therapies aimed at addressing devastating and rare diseases. Cytonus employs a synthetic biology approach through its proprietary Cargocyte technology, which enables precision delivery of therapeutics and in vivo production of innovative treatments. By integrating AI-driven drug discovery methods, Cytonus is focused on creating first-in-class therapeutics to treat immune-related disorders effectively.
iotaMotion, Inc. is a company focused on developing and manufacturing innovative cochlear ear implants to address hearing loss. Established in 2015 and based in Iowa City, Iowa, iotaMotion offers a robotic-assisted surgical system that standardizes the insertion of cochlear implant electrodes. This system is designed to enhance accessibility for both surgeons and patients, effectively reducing surgical variability by controlling the speed and acceleration of electrode insertion. By personalizing the insertion approach, iotaMotion enables healthcare professionals to deliver more precise and individualized cochlear intervention treatments, ultimately improving patient outcomes in hearing restoration.
PhotoniCare is a medical device company that develops ear-diagnosis devices using light-based technology to see through the eardrum into the middle ear, enabling clinicians to visualize the contents and determine whether antibiotics or surgical interventions are needed. Its flagship device, TOMi Scope, uses near-infrared light to provide views beyond the eardrum and support assessment through optical coherence imaging. The company's imaging platform aims to extend its applications beyond otology and improve clinical decision-making in middle-ear infections. PhotoniCare was founded in 2013 and is based in Champaign, Illinois.
Neurodon Corporation is a biopharmaceutical company focused on discovering and developing disease-modifying therapeutic candidates for intractable diseases. Established in 2019 and headquartered in Crown Point, Indiana, Neurodon specializes in molecular therapies that address endoplasmic reticulum (ER) stress, a significant factor in cell dysfunction and death. The company's innovative approach aims to restore calcium homeostasis through first-in-class modulators, addressing conditions such as Alzheimer's disease, Parkinson's disease, Huntington's disease, diabetes, and other rare diseases. Neurodon has made significant progress, with two candidates currently in IND-enabling studies and plans to enter clinical trials in 2025. The company has raised over $11 million through various funding sources, including state and federal grants, partnerships, and angel investments, and is actively seeking additional funding to support its first human studies for diabetes and rare disease programs.
Cleveland Clinic
Grant in 2020
Cleveland Clinic is a non-profit academic medical center that integrates clinical and hospital care with research and education. Its mission is to provide better care for the sick, investigate medical problems, and advance the education of those who serve.
Cytonus Therapeutics
Grant in 2020
Cytonus Therapeutics, Inc. is a biotechnology company founded in 2018 and located in Columbus, Ohio. The company specializes in developing immune-oncology and gene therapies aimed at addressing devastating and rare diseases. Cytonus employs a synthetic biology approach through its proprietary Cargocyte technology, which enables precision delivery of therapeutics and in vivo production of innovative treatments. By integrating AI-driven drug discovery methods, Cytonus is focused on creating first-in-class therapeutics to treat immune-related disorders effectively.
Washington University School Of Medicine
Grant in 2019
Washington University School of Medicine is the medical school of Washington University in St. Louis.A leader in medical research, teaching and patient care, Washington University School of Medicine is currently ranked fourth in the nation by U.S. News & World Report.
The School’s 2,100 employed and volunteer faculty physicians and clinicians -- known as Washington University Physicians -- are also medical staff members of Barnes-Jewish and St. Louis Children’s hospitals. The clinical practice group provides care to more than 430,000 children and adults at 49 clinical sites annually.
Together, the institutions located on the Washington University Medical Center campus employ more than 21,000 clinicians, scientists, residents, fellows, administrators and support staff.
Cleveland Clinic
Grant in 2019
Cleveland Clinic is a non-profit academic medical center that integrates clinical and hospital care with research and education. Its mission is to provide better care for the sick, investigate medical problems, and advance the education of those who serve.
OmniLife, Inc. is a specialized communication platform focused on enhancing care coordination for transplant patients and their healthcare teams. Founded in 2016 and based in Coralville, Iowa, the company offers TXP Chat, a mobile messaging application designed to facilitate communication related to organ referrals, allocation, procurement, and transplantation. OmniLife serves a diverse array of providers within the healthcare industry, including hospital systems, Accountable Care Organizations (ACOs), and group practices. The platform is unique in its ability to manage the entire workflow of transplant programs, addressing critical aspects such as organ intake management, patient referrals, evaluations, and waitlist management. By streamlining these processes, OmniLife aims to improve the efficiency and effectiveness of life-saving medical care.
Xoran Technologies
Grant in 2019
Xoran Technologies designs and manufactures computed tomography imaging systems for point-of-care diagnosis. The company offers MiniCAT, a high-resolution CT system for bone window imaging of the sinuses, temporal bones, and skull base; Xoran xCAT, a mobile cone-beam CT system that delivers high-resolution 3D images; and XoranConnect, a web-based tool for viewing and archiving medical images. It also provides LuminX digital radiography systems, including an overhead robotic DR suite, a floor-mounted tube stand, and U-Arm and straight-arm configurations. Founded in 2001 and based in Ann Arbor, Michigan, Xoran focuses on patient-friendly imaging solutions designed to enable instant diagnosis at the point of care, with an emphasis on accessible, low radiation dose CT imaging to support clinicians.
University of Illinois Chicago
Grant in 2019
A major research university in the heart of one of the world's greatest cities, UIC provides a world-class education for its students. We are committed to creating and disseminating new knowledge as a university of growing national and international stature.
The largest university in the Chicago area, UIC has 27,580 students, 15 colleges-including the nation's largest medical school-and annual research expenditures exceeding $335 million. UIC operates the state's major public medical center and serves as the principal educator of Illinois' physicians, dentists, pharmacists, nurses and other health-care professionals.
A truly global institution, more than a third of UIC students speak English as a second language. UIC's student body-approximately 61 percent undergraduate and 39 percent graduate and professional-is recognized as one of the nation's most diverse. We consider this one of our greatest strengths.
Founded in 2008 by Dr. Michela Gallagher, AgeneBio is a neuroscience pharmaceutical company dedicated to developing treatments for memory disorders. Its primary focus is on Amnestic Mild Cognitive Impairment (aMCI) and Alzheimer's disease (AD), aiming to prevent neurodegeneration and preserve cognitive function.
University of Missouri
Grant in 2019
Founded in 1839, the University of Missouri is a comprehensive public university located in Columbia, Missouri. It offers over 280 degree programs across various fields, including medicine and law. With around 30,000 students from diverse backgrounds, Mizzou is known for its competitive admissions process considering factors such as GPA, SAT/ACT scores, and extracurricular involvement. The university provides academic merit scholarships and federal aid to support students financially.
Recovery Force
Grant in 2019
Founded in 2013, Recovery Force is a digital health company specializing in wearable medical technology. It manufactures and supplies healthcare apparel, including sleeves and shoes, designed to enhance circulation, reduce post-operative pain, and improve patient mobility.
Precision Virologics
Grant in 2019
Precision Virologics, Inc. is a biotechnology company based in Saint Louis, Missouri, focused on developing biologically targeted vaccines for emerging infectious diseases. Established in 2016, the company utilizes an innovative adenoviral vector technology that incorporates camelid antibodies directed towards activated dendritic cells, effectively delivering proprietary antigen epitopes to target pathogens. One of its key vaccine candidates is PV-ZIKV, designed to combat the Zika virus, which boasts advantages such as a lack of cross-reactivity among flaviviruses and enhanced potency compared to competitors. Precision Virologics aims to provide next-generation vaccines that not only address Zika but also have the potential to target other infectious diseases like chikungunya and dengue, facilitating more effective immune responses.
The University of Chicago Medicine
Grant in 2018
The University of Chicago Medicine is an academic medical institution that operates as a hospital which provides healthcare services. In addition, it provides medical education.
The University of Chicago Medicine is comprised of the University of Chicago Pritzker School of Medicine; University of Chicago Biological Sciences Division; and University of Chicago Medical Center.
The institution’s physicians are members of the University of Chicago Physicians Group which includes about 900 physicians and covers the full array of medical and surgical specialties. Its physicians are faculty members of the Pritzker School of Medicine.
The University of Chicago Medicine was founded in 1927 and is based in Chicago, Illinois.
Founded in 2008 by Dr. Michela Gallagher, AgeneBio is a neuroscience pharmaceutical company dedicated to developing treatments for memory disorders. Its primary focus is on Amnestic Mild Cognitive Impairment (aMCI) and Alzheimer's disease (AD), aiming to prevent neurodegeneration and preserve cognitive function.
Novosteo Inc. is a biotechnology company based in West Lafayette, Indiana, founded in 2017. The firm specializes in developing and manufacturing innovative drugs aimed at healing bone fractures and addressing related conditions that significantly impact patients' morbidity, mortality, and quality of life. With scientific guidance from co-founders Stewart Low and Philip Low of Purdue University, Novosteo utilizes a proprietary chemistry approach to bone targeting, which allows for the delivery of anabolic agents directly to fracture surfaces. This unique method focuses on accelerating bone regeneration and improving healing outcomes, thereby mitigating the debilitating effects associated with bone injuries and enhancing patient mobility and productivity.
Precision Virologics
Grant in 2018
Precision Virologics, Inc. is a biotechnology company based in Saint Louis, Missouri, focused on developing biologically targeted vaccines for emerging infectious diseases. Established in 2016, the company utilizes an innovative adenoviral vector technology that incorporates camelid antibodies directed towards activated dendritic cells, effectively delivering proprietary antigen epitopes to target pathogens. One of its key vaccine candidates is PV-ZIKV, designed to combat the Zika virus, which boasts advantages such as a lack of cross-reactivity among flaviviruses and enhanced potency compared to competitors. Precision Virologics aims to provide next-generation vaccines that not only address Zika but also have the potential to target other infectious diseases like chikungunya and dengue, facilitating more effective immune responses.
Neurodon Corporation is a biopharmaceutical company focused on discovering and developing disease-modifying therapeutic candidates for intractable diseases. Established in 2019 and headquartered in Crown Point, Indiana, Neurodon specializes in molecular therapies that address endoplasmic reticulum (ER) stress, a significant factor in cell dysfunction and death. The company's innovative approach aims to restore calcium homeostasis through first-in-class modulators, addressing conditions such as Alzheimer's disease, Parkinson's disease, Huntington's disease, diabetes, and other rare diseases. Neurodon has made significant progress, with two candidates currently in IND-enabling studies and plans to enter clinical trials in 2025. The company has raised over $11 million through various funding sources, including state and federal grants, partnerships, and angel investments, and is actively seeking additional funding to support its first human studies for diabetes and rare disease programs.
Intact Genomics
Grant in 2018
Intact Genomics specializes in large DNA fragment cloning and metagenomic technologies. Located in St. Louis, Missouri, they offer services to explore the genome structure and function of various species.
The Indiana CTSI
Grant in 2018
The Indiana CTSI is dedicated to leveraging and strengthening the state’s life sciences community to achieve better health for people in Indiana.Leadership and staff at the Indiana CTSI are working to develop the best processes and resources to enable the efficient translation of scientific discoveries to patient care.Indiana CTSI programs and partnerships are designed to educate, attract and retain top research talent in the state for generations to come.
Kent State University
Grant in 2018
Kent State University, located in Kent, Ohio, is a prominent public doctoral university established in 1910, recognized for its high research activity. As the highest-ranking public university in Northern Ohio, it offers a diverse array of academic programs, including undergraduate majors in fields such as Biomedical Sciences, Communication Studies, Psychology, and Visual Communication and Design. Students have access to over 300 academic programs across Kent State's eight campuses and can participate in more than 200 student organizations, fostering a vibrant campus life. The university provides various financial aid options, including need-based awards and graduate assistantships, to support students in their educational pursuits. Admissions for freshmen require a minimum GPA and standardized test scores, though alternative pathways exist for those who do not meet these criteria. Kent State University plays a vital role in the educational landscape of Ohio, contributing to the development of its students through comprehensive academic and extracurricular offerings.
Humanetics Corporation
Grant in 2018
Humanetics Corporation is a clinical-stage pharmaceutical company based in Edina, Minnesota, founded in 1988. The company specializes in the discovery, development, and commercialization of drugs targeting urgent medical needs, particularly in the areas of oncology and biodefense. Humanetics focuses on radiation modulators, with its lead candidate BIO 300 designed to protect normal tissues from radiation damage and to treat the effects of acute radiation exposure, such as radiation-induced pneumonitis and pulmonary fibrosis. The company has developed BIO 300 for applications in both oncology and medical countermeasures. Since 2003, Humanetics has collaborated with the Armed Forces Radiobiology Research Institute to advance its research, leading to the progression of multiple clinical programs targeting various solid tumors, including lung, prostate, head and neck cancers.
Artio Medical
Grant in 2018
Artio Medical, Inc. is a medical device company focused on developing and commercializing catheter-based solutions for cardiovascular diseases. Based in Olathe, Kansas, the company specializes in endovascular devices designed for embolization of vessels, aneurysms, and other vascular structures. Its product offerings include Solus Gold and Solus Flex, both embolization devices featuring unique delivery systems, as well as Aneura and Endura, which combine coils and accessory balloons for the immediate occlusion of saccular and cerebral aneurysms, respectively. Artio Medical was founded in 2011 and was previously known as Metactive Medical, Inc. before rebranding in February 2020. The company operates as a subsidiary of Novita Therapeutics, LLC, and its innovations aim to enhance the speed and safety of vascular occlusion procedures for physicians.
University of Illinois Chicago
Grant in 2018
A major research university in the heart of one of the world's greatest cities, UIC provides a world-class education for its students. We are committed to creating and disseminating new knowledge as a university of growing national and international stature.
The largest university in the Chicago area, UIC has 27,580 students, 15 colleges-including the nation's largest medical school-and annual research expenditures exceeding $335 million. UIC operates the state's major public medical center and serves as the principal educator of Illinois' physicians, dentists, pharmacists, nurses and other health-care professionals.
A truly global institution, more than a third of UIC students speak English as a second language. UIC's student body-approximately 61 percent undergraduate and 39 percent graduate and professional-is recognized as one of the nation's most diverse. We consider this one of our greatest strengths.
SentiAR is a digital health software company developing a 3D augmented reality holographic platform that provides real-time visualization of a patient’s anatomy and catheter location during interventional procedures. Spun out from Washington University, it uses real-time mapping data and imaging from CT/MRI to render holographic views over the patient in the catheterization laboratory, with clinician-controlled visualization. The platform aims to improve precision and safety in procedures addressing cardiac arrhythmias. The company focuses on delivering an immersive visualization solution for interventional cardiology and related specialties.
Case Western Reserve University
Grant in 2018
Case Western Reserve University (CWRU) is a private research university located in Cleveland's University Circle. Established in 1843, it comprises various schools including Medicine, Law, Engineering, Arts and Sciences, Nursing, Social Sciences, Dental Medicine, Management, and Mandel School of Applied Social Sciences. CWRU is renowned for its biomedical discoveries, medical education, and top-ranked programs such as international law, health law, and intellectual property law. It offers practical experiences like real-client work and full-time practice experiences to students across various disciplines. The university is accredited by several professional associations and holds membership in the Association of American Universities.
Cleveland Clinic
Grant in 2017
Cleveland Clinic is a non-profit academic medical center that integrates clinical and hospital care with research and education. Its mission is to provide better care for the sick, investigate medical problems, and advance the education of those who serve.
Washington University in St. Louis
Grant in 2017
Founded in 1853, Washington University in St. Louis is a medium-sized, independent university dedicated to challenging its faculty and students to pursue new knowledge and understanding in an ever-changing world. It promotes higher education and rigorous research as fundamental to an open, vibrant society.
Nervive Inc. is a medical device company based in Akron, Ohio, that specializes in developing innovative treatments for brain ischemia. Established in 2010, Nervive has created VitalFlow, a non-invasive platform technology designed to address various conditions associated with brain ischemia, including cerebral artery vasospasm, ischemic stroke, and traumatic brain injury. By focusing on research, development, and commercialization, the company aims to enhance patient outcomes and facilitate faster recovery for individuals affected by these critical neurological conditions.
Washington University School Of Medicine
Grant in 2017
Washington University School of Medicine is the medical school of Washington University in St. Louis.A leader in medical research, teaching and patient care, Washington University School of Medicine is currently ranked fourth in the nation by U.S. News & World Report.
The School’s 2,100 employed and volunteer faculty physicians and clinicians -- known as Washington University Physicians -- are also medical staff members of Barnes-Jewish and St. Louis Children’s hospitals. The clinical practice group provides care to more than 430,000 children and adults at 49 clinical sites annually.
Together, the institutions located on the Washington University Medical Center campus employ more than 21,000 clinicians, scientists, residents, fellows, administrators and support staff.
Cleveland Clinic
Grant in 2017
Cleveland Clinic is a non-profit academic medical center that integrates clinical and hospital care with research and education. Its mission is to provide better care for the sick, investigate medical problems, and advance the education of those who serve.
University of Michigan
Grant in 2017
The University of Michigan, one of the largest universities in the Midwest, offers a diverse array of academic programs that attract over 40,000 undergraduate, graduate, and professional students. Its renowned schools include the Stephen Ross School of Business, the College of Engineering, and prominent law and medical schools. The university also has a vibrant arts scene, highlighted by its Musical Theatre program and the annual Ann Arbor Film Festival, which draws filmmakers globally. In addition to its educational endeavors, the University of Michigan actively manages a significant endowment, investing in alternative assets such as private equity, real estate, and infrastructure to support its mission and enhance its resources. The institution consistently ranks highly in national assessments, reflecting its commitment to academic excellence and innovation.
Fast Biomedical
Grant in 2017
Fast Biomedical is a clinical-stage medical technology company based in Indiana, dedicated to the development and commercialization of an innovative technology for quantifying critical health parameters that have historically been difficult to measure. The company's primary focus is on assessing blood volume and kidney function in a clinically viable manner. Fast Biomedical's technology utilizes a fluorescent compound to enhance the detection of kidney infections, allowing for faster identification of acute kidney failure compared to traditional lab tests. By injecting markers into a patient's bloodstream that fluoresce when analyzed with their device, physicians can more effectively monitor kidney health and improve patient outcomes.
Genomenon, Inc. is a software development company based in Ann Arbor, Michigan, that specializes in tools for genetic diagnosis and discovery. Founded in 2014, it provides a suite of diagnostic and discovery solutions that enable physicians, researchers, and pharmaceutical companies to rapidly and accurately identify disease-causing variants from genomic sequencing data. The company’s flagship product, GENOMENON, automates the analysis of next-generation sequencing data, thereby enhancing decision-making processes in clinical settings and accelerating discoveries in genomics. With its focus on improving cancer diagnosis and treatment, Genomenon aims to support better patient outcomes through its innovative software solutions.
ONL Therapeutics
Grant in 2017
ONL Therapeutics is a biopharmaceutical company headquartered in Ann Arbor, Michigan, that develops small‑molecule peptide therapeutics to protect photoreceptors and preserve vision. Its pipeline focuses on targeting the FAS apoptotic pathway to prevent photoreceptor loss in retinal diseases such as retinal detachment, aiming to improve surgical outcomes and reduce vision loss. Founded in 2006, the company seeks to bring novel treatments for serious, vision‑threatening retinal conditions.
Indiana University Bloomington
Grant in 2017
Founded in 1820, Indiana University Bloomington is a public research-intensive university committed to liberal arts and sciences education. It offers professional, medical, and technological programs, aiming to create, disseminate, preserve, and apply knowledge through cutting-edge research, scholarship, and creative activity.
Stem Pharm develops synthetic biomaterials and neural organoid platforms to support drug discovery, toxicity screening, and regenerative medicine. Founded in 2015 and based near the University of Wisconsin campus in Fitchburg, the company leverages biomaterials science and cell-material interactions to create organoid models and cell-friendly coatings for manufacturing cell-based therapies. It focuses on brain-related inflammation and uses neural organoid technology as a discovery platform, while also producing hydrogel biomaterials that support cell and tissue culture for disease modeling, drug discovery, and toxicology applications.
Cleveland Clinic
Grant in 2016
Cleveland Clinic is a non-profit academic medical center that integrates clinical and hospital care with research and education. Its mission is to provide better care for the sick, investigate medical problems, and advance the education of those who serve.
SAb Biotherapeutics
Grant in 2016
SAB Biotherapeutics is a clinical-stage biopharmaceutical company established in 2014, headquartered in Sioux Falls, South Dakota with additional offices in Cambridge, Massachusetts. The company specializes in developing immunotherapies using its proprietary DiversitAb platform, which employs transchromosomic cattle to produce large quantities of targeted human polyclonal antibodies without relying on human plasma or serum. SAB's pipeline includes therapies for conditions such as Type 1 diabetes (SAB-142), seasonal influenza (SAB-176), and Middle East Respiratory Syndrome Coronavirus (MERS-CoV, SAB-301).
Intact Genomics
Grant in 2016
Intact Genomics specializes in large DNA fragment cloning and metagenomic technologies. Located in St. Louis, Missouri, they offer services to explore the genome structure and function of various species.
Founded in 1863, Mayo Clinic is a non-profit organization based in Minnesota, United States. It provides comprehensive medical care services across various specialties, conducts extensive research, and offers education in clinical medicine.
SpeechVive Inc. is a medical technology company based in Lafayette, Indiana, that focuses on developing innovative communication solutions for individuals with Parkinson's disease. Founded in 2011, the company specializes in the design and manufacture of a wearable speech device aimed at enhancing the speech capabilities of patients. This device effectively reduces background noise, thereby improving the user's ability to hear and facilitating increased speech volume and clarity. By addressing the communication challenges faced by those with Parkinson's disease, SpeechVive aims to help patients lead more normal and fulfilling lives.
KinaSense LLC is a biotechnology company focused on developing innovative products for cancer drug testing during the pre-clinical and clinical phases of drug discovery. Based in West Lafayette, Indiana, the company specializes in cancer diagnostic solutions and drug discovery technologies, particularly in the area of tyrosine kinase inhibitors (TKIs), which are employed in treating various cancer types. KinaSense aims to enhance the predictive capabilities of current diagnostic tools, enabling healthcare providers to match patients more effectively with the appropriate TKIs based on individual responses. Through its assays and cell-based kits, KinaSense is committed to improving patient outcomes by facilitating personalized care tailored to the specific efficacy and selectivity of TKIs. Established in 2013, the company continues to focus on advancing cancer treatment through its innovative approaches.
Stemina Biomarker Discovery
Grant in 2015
Stemina Biomarker Discovery, Inc. is a company based in Madison, Wisconsin, that specializes in the discovery and development of human cellular models and molecular biomarkers aimed at improving drug safety and human health. Founded in 2006, Stemina focuses on toxicity screening for drug candidates, chemical compounds, and various consumer products, including cosmetics and tobacco ingredients. Its notable offerings include the Cardio quickPredict, a cardiotoxicity assay that assesses the potential cardiotoxic effects of compounds using human induced pluripotent stem cell-derived cardiomyocytes. Additionally, the devTOX quickPredict assay evaluates developmental toxicity, while the devTOXqp assay utilizes human embryonic and induced pluripotent stem cells to signal potential disruptions to human development. The company employs metabolomics and mass spectrometry to analyze the metabolic responses of cells to various substances, facilitating insights into human responses and enhancing the drug development process.
Northwestern University
Grant in 2015
Northwestern University, established in 1851, is a comprehensive research university offering over 120 undergraduate programs and more than 140 graduate and professional degrees across its 12 schools and colleges. It provides educational services, including internship opportunities, career guidance, financial aid options such as loans, grants, and scholarships, and exam certification resources to its approximately 8,500 undergraduate students and 9,000 graduate/professional students. The university is renowned for its law school, founded in 1859, which offers Juris Doctor (J.D.) degrees and various master's programs, along with executive education and clinical legal education opportunities. Northwestern University is headquartered in Evanston, Illinois, with additional campuses in Chicago and Doha, Qatar.
Isto Technologies
Grant in 2015
ISTO Technologies, Inc., an orthobiologics company, develops biologic products to regenerate and restore function to damaged cartilage and bone. It offers InQu, a resorbable bone graft extender and substitute; NuQu, a cell-based injectable therapy for disc regeneration; and DeNovo ET, an engineered cartilage implant for the repair and regeneration of knee cartilage. The company provides its products through distributors. ISTO Technologies, Inc. was founded in 1997 and is based in St. Louis, Missouri.
Sterilucent
Venture Round in 2015
Sterilucent is a healthcare company based in Minneapolis, Minnesota, founded in 2004. It specializes in the development and marketing of vaporized hydrogen peroxide technology, which provides innovative sterilization products. The company's offerings are designed to effectively sterilize moisture and heat-sensitive reusable medical devices, ensuring that they are safe and properly prepared for patient procedures. Sterilucent's sterilization solutions are noted for their low operating costs and efficiency, making them valuable for healthcare facilities aiming to maintain high standards of patient safety and equipment reliability.
Xavier University
Grant in 2014
Xavier University, established in 1831 in Cincinnati, Ohio, is a Jesuit Catholic institution that serves approximately 7,000 students. It offers a diverse range of educational opportunities through its three colleges, providing more than 90 undergraduate majors, 55 minors, and 19 graduate programs. As the sixth-oldest Catholic university in the United States, Xavier is one of 28 Jesuit colleges and universities across the country, emphasizing a commitment to academic excellence and the development of ethical leadership. As a non-profit organization, it focuses on nurturing the intellectual and moral growth of its students within a supportive educational environment.
Founded in 1863, Mayo Clinic is a non-profit organization based in Minnesota, United States. It provides comprehensive medical care services across various specialties, conducts extensive research, and offers education in clinical medicine.
North Dakota University
Grant in 2014
The University of North Dakota (UND), located in Grand Forks, North Dakota, is recognized as one of the top 100 doctoral research universities in the United States. Established in 1883, UND offers a diverse array of over 300 undergraduate, master’s, and doctoral programs, including the prestigious School of Aerospace Sciences. The university focuses on academic excellence and integrity, providing students with numerous opportunities for personal growth and leadership development. With a vibrant campus life, students can engage in more than 200 clubs and organizations, participate in events such as career fairs and international food festivals, and contribute to various philanthropic activities. Admissions require prospective students to submit applications along with official transcripts and standardized test scores, with favorable tuition rates for North Dakota residents. The university also offers a range of financial aid options, including scholarships, grants, and work-study programs, encouraging students to pursue their educational goals while benefiting from a supportive academic environment.
IntelliWheels
Grant in 2014
IntelliWheels, Inc. is a startup based at the University of Illinois at Urbana-Champaign that focuses on developing innovative technology to enhance mobility options for wheelchair users. The company offers a range of products, including specialized wheelchair gloves and easy push wheels, which aim to improve grip and ease of movement for users. These products are designed to fit comfortably in the hands of wheelchair users, ultimately promoting increased physical activity, independence, and overall well-being. Through its advancements in wheelchair technology, IntelliWheels seeks to address the unique challenges faced by individuals who rely on wheelchairs for mobility.
Northwestern University
Grant in 2014
Northwestern University, established in 1851, is a comprehensive research university offering over 120 undergraduate programs and more than 140 graduate and professional degrees across its 12 schools and colleges. It provides educational services, including internship opportunities, career guidance, financial aid options such as loans, grants, and scholarships, and exam certification resources to its approximately 8,500 undergraduate students and 9,000 graduate/professional students. The university is renowned for its law school, founded in 1859, which offers Juris Doctor (J.D.) degrees and various master's programs, along with executive education and clinical legal education opportunities. Northwestern University is headquartered in Evanston, Illinois, with additional campuses in Chicago and Doha, Qatar.
TCARE, Inc. is a company that specializes in developing a caregiver support software-as-a-service (SaaS) solution aimed at preventing family caregiver burnout. Founded in 2017 and based in Saint Louis, Missouri, TCARE offers a cloud-based technology suite that allows care professionals to assess risk factors associated with caregiver burnout and implement timely interventions. Its platform serves various stakeholders, including organizations, care professionals, and family caregivers across the United States. By providing an evidence-based support program, TCARE not only aids in delaying or preventing nursing home placements but also helps reduce long-term care claims for Medicaid and life insurance carriers.
University of Nebraska Medical Center
Grant in 2013
University of Nebraska Medical Center is the public center of health sciences research, patient care, and education in Omaha, Nebraska. It delivers education across medical and health fields, including nursing, pharmacy, physical therapy, physician assisting, and dental and medical training, with programs that train future doctors and dentists. The center conducts extensive research at its Durham Research Centers, pursuing advances in cancer treatments and transplant medicine. Small class sizes and close collaboration with faculty provide hands-on learning. It supports allied health programs such as clinical laboratory science, cytotechnology, medical sonography, and radiation therapy, and offers funding through research assistantships and fellowships. Beyond education and research, UNMC aims to improve patient care and contribute to the health of its state and communities through outreach and discovery.
Washington University School Of Medicine
Grant in 2013
Washington University School of Medicine is the medical school of Washington University in St. Louis.A leader in medical research, teaching and patient care, Washington University School of Medicine is currently ranked fourth in the nation by U.S. News & World Report.
The School’s 2,100 employed and volunteer faculty physicians and clinicians -- known as Washington University Physicians -- are also medical staff members of Barnes-Jewish and St. Louis Children’s hospitals. The clinical practice group provides care to more than 430,000 children and adults at 49 clinical sites annually.
Together, the institutions located on the Washington University Medical Center campus employ more than 21,000 clinicians, scientists, residents, fellows, administrators and support staff.
NeoClone is a research-oriented company established in 1999 by three scientists from the University of Wisconsin, focusing on the development of monoclonal antibodies for biotechnology and research applications. The company employs retroviral transformation technology to enhance the production process of monoclonal antibodies, which allows for quicker development times and reduced costs. This innovative approach enables NeoClone to deliver customized antibodies to researchers and scientists more efficiently, addressing the growing demand for advanced antibody solutions in various scientific fields.
Promentis Pharmaceuticals
Grant in 2012
Founded in 2006, Promentis Pharmaceuticals is a biopharmaceutical company based in Milwaukee, Wisconsin. It develops therapies targeting the central nervous system for treating neuropsychiatric disorders such as impulse control disorders and obsessive-compulsive disorder.
AquaMost, Inc. is a Madison, Wisconsin-based company specializing in the development and manufacturing of chemical-free water treatment solutions. Founded in 2006, AquaMost's flagship product, the SX Reactor, integrates multiple bacteria-killing technologies, including onsite generation of chlorine and hydroxyl radicals combined with ultraviolet irradiation, achieving over 99% efficacy in eliminating bacteria. This innovative system is particularly tailored for the oil and gas industry, but its applications extend to various sectors including food and beverage, drinking water treatment, dairy, and other industrial uses. AquaMost also provides delivery, setup, and maintenance support for its systems, which have been deployed in regions such as Texas, Colorado, Utah, and Canada.
NeoClone is a research-oriented company established in 1999 by three scientists from the University of Wisconsin, focusing on the development of monoclonal antibodies for biotechnology and research applications. The company employs retroviral transformation technology to enhance the production process of monoclonal antibodies, which allows for quicker development times and reduced costs. This innovative approach enables NeoClone to deliver customized antibodies to researchers and scientists more efficiently, addressing the growing demand for advanced antibody solutions in various scientific fields.
Isto Technologies
Grant in 2002
ISTO Technologies, Inc., an orthobiologics company, develops biologic products to regenerate and restore function to damaged cartilage and bone. It offers InQu, a resorbable bone graft extender and substitute; NuQu, a cell-based injectable therapy for disc regeneration; and DeNovo ET, an engineered cartilage implant for the repair and regeneration of knee cartilage. The company provides its products through distributors. ISTO Technologies, Inc. was founded in 1997 and is based in St. Louis, Missouri.