National Institutes of Health

The National Institutes of Health (NIH) is a leading biomedical research facility in the United States, operating under the Department of Health and Human Services. Established in 1887 and based in Bethesda, Maryland, NIH is the primary agency responsible for biomedical and health-related research in the country. It comprises 27 separate institutes and centers, each focusing on different disciplines within biomedical science. NIH conducts its own scientific research through the Intramural Research Program and provides significant funding for research at external institutions via the Extramural Research Program. With a workforce that includes 1,200 principal investigators and over 4,000 postdoctoral fellows, NIH has been instrumental in major medical breakthroughs, such as the development of vaccines for hepatitis and human papillomavirus, as well as the discovery of treatments for various health conditions. As the world's largest source of medical research funding, NIH continues to advance scientific knowledge and contribute to public health improvements.

Francis Collins

Director

Nick Langhals

Supervisory Program Director

Past deals in Health Diagnostics

LUCID DIAGNOSTICS

Grant in 2025
Lucid Diagnostics is a commercial-stage, cancer-prevention medical diagnostics company. Lucid focuses on patients with gastroesophageal disease (GERD), also known as chronic heartburn, who are at risk of developing esophageal precancer and cancer. Lucid’s EsoGuard Esophageal DNA Test is performed on samples collected in a brief noninvasive office procedure with its EsoCheck Esophageal Cell Collection Device, a diagnostic test capable of serving as a widespread screening tool to prevent cancer and cancer deaths through early detection of esophageal precancer in at-risk GERD patients.

University of Arkansas for Medical Sciences

Grant in 2025
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

BioCircuit Technologies

Grant in 2024
BioCircuit Technologies, Inc. is a medical device company based in Atlanta, Georgia, founded in 2016. The company specializes in developing noninvasive electrophysiology devices that monitor, control, and repair peripheral nerves. By utilizing multi-electrode arrays and proprietary algorithms, BioCircuit's products enable clinicians to diagnose health conditions more effectively, track the progression of symptoms over time, and select tailored treatments for individual patients. This innovative approach enhances the ability of healthcare providers to address nerve-related health issues with greater precision and efficiency.

Novel Microdevices

Grant in 2024
Novel Microdevices, LLC is a medical device company that specializes in the development of handheld devices for molecular diagnostics. Founded in 2014 and headquartered in Annapolis, Maryland, the company has created the NOVEL DX device, which employs microfluidics technology to analyze raw biological samples at the point of care. This device delivers results in approximately 30 minutes, allowing healthcare professionals to achieve lab-quality diagnostics without the need for a traditional laboratory setting. Novel Microdevices caters to various sectors, including clinical diagnostics, biodefense, food safety, forensics, drug discovery, animal care, and agriculture, thus addressing a wide range of applications in health and safety.

CareTaker Medical

Grant in 2024
CareTaker Medical develops wireless patient monitoring devices. Its flagship product, CareTaker, is a wearable system that measures continuous beat-by-beat blood pressure, heart rate, respiration rate, and other hemodynamic parameters using only a finger cuff. The device securely transmits data over cellular networks or Bluetooth to enable remote patient monitoring within hospitals and during transport.

Pip Care

Grant in 2024
Pip Care is a healthcare company offering a personalized surgical journey platform that digitizes and automates perioperative processes for health systems. The platform supports care teams from preparation to recovery, with a perioperative care app to help patients prepare for and recover from surgery. The company also provides certified health coaches who develop personalized recovery plans with daily tasks and curated advice, enabling patients to track appointments and stay prepared. By aligning care teams and patient steps, Pip Care aims to improve surgical outcomes and efficiency for health systems.

Teal Health

Grant in 2024
Teal Health specializes in developing at-home cervical cancer screening devices, aiming to enhance convenience, privacy, and accessibility for women. Their FDA-approved platform includes a sampling device, virtual consultations with licensed providers, secure laboratory testing, an online results portal, and coordination of follow-up care.

Amissa Health

Grant in 2024
Amissa develops mobile and wearable application solutions aimed at alleviating the challenges of Alzheimer's care. The company’s technology empowers caregivers by allowing them to geo-fence and locate loved ones who may wander, remotely monitor their activity and health, and predict behaviors associated with Alzheimer's. In addition to these features, Amissa offers wearable biosensors integrated with a cloud-based data platform that collects biometric data on activity levels, sleep patterns, and physiological changes. This comprehensive approach not only aids caregivers in monitoring patients but also provides valuable insights for researchers seeking to understand disease progression, ultimately enhancing the quality of life for individuals with dementia and related disorders.

Lasarrus

Grant in 2024
Lasarrus is a medical device company founded in 2013 and headquartered in Baltimore, Maryland. The company specializes in developing wearable devices aimed at enhancing the physical therapy experience for patients, particularly those with chronic obstructive pulmonary disease. Lasarrus's innovative device facilitates remote monitoring and telemedicine by capturing physiological and range-of-motion data from various points on the body. This technology provides patients with an affordable, comfortable, and non-invasive means to track their health routines and accelerate their recovery process.

Subtle Medical

Grant in 2024
Subtle Medical is a healthcare technology company that develops artificial‑intelligence software for magnetic resonance and positron emission tomography imaging. Its flagship products, SubtleMR and SubtlePET, are FDA‑cleared and CE‑marked tools that enhance image quality by reducing noise and sharpening detail, allowing scans to be performed faster and with lower radiation or contrast dose. The company’s deep‑learning algorithms integrate with any scanner without changing existing workflows, enabling imaging centers and hospitals to increase throughput and improve patient safety. Subtle Medical also offers a vendor‑agnostic AI platform that delivers analytics and support to clinical imaging providers. Founded in 2017 and headquartered in Menlo Park, California, the firm has received an NIH SBIR grant and an RSNA award for its GAD technology.

Precision Epigenomics

Grant in 2024
Precision Epigenomics, established in 2020 and based in Tucson, Arizona, specializes in molecular diagnostics for cancer. The company focuses on developing innovative molecular diagnostic assays, leveraging DNA methylation analysis, an epigenetic modification, to enhance cancer diagnosis and treatment. Their offerings aim to address unmet clinical needs, aiding clinicians in improved patient management.

Penderia Technologies

Grant in 2024
Penderia Technologies is a medical device company focused on innovative orthopedic solutions. It develops implantable, battery-less sensors for monitoring injury and healing progress in real-time, enabling personalized rehabilitation therapies.

University of Arkansas for Medical Sciences

Grant in 2024
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Immunovia

Grant in 2024
Immunovia is a diagnostics company focused on the early detection of pancreatic cancer and other complex diseases. It develops and commercializes innovative diagnostic tools using its proprietary technology platform, IMMray, which is based on antibody microarray analysis. The company conducts clinical trials and validation studies to ensure the accuracy and reliability of its tests. By collaborating with medical institutions and research centers worldwide, Immunovia aims to bring its diagnostic solutions to market, significantly impacting the treatment and management of pancreatic cancer and potentially improving survival rates. Its approach to utilizing blood-based biomarkers may also enable early detection strategies for other cancers and autoimmune diseases.

Metabolon

Grant in 2024
Metabolon develops metabolomics-based platforms and clinical diagnostic tests for early disease detection and precision medicine. It offers blood tests like QUANTOSE IR and QUANTOSE IGT, and Meta IMD for inherited metabolic disorders. The company serves various sectors including academia, biotech/pharmaceuticals, and precision medicine. It has strategic partnerships with major pharmaceutical companies and other industries.

Nanopath

Grant in 2024
Nanopath is a molecular diagnostics company that develops innovative platforms for rapid disease diagnosis. Its technology enables point-of-care testing, eliminating the need for nucleic acid amplification and supporting multiplexed detection. This allows patients and healthcare providers to access accurate diagnostic results within standard office visits, improving healthcare outcomes.

University of Arkansas for Medical Sciences

Grant in 2024
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Behaivior

Grant in 2024
Behaivior LLC is a digital health company based in Pittsburgh, Pennsylvania, focused on predicting and preventing addiction relapses through innovative technology. Founded in 2017, Behaivior integrates wearable devices with machine learning algorithms to analyze real-time data from various physiological metrics, such as heart rate and skin temperature. The company’s platform, known as Recovery, employs this data to deliver timely interventions tailored to the needs of individuals in recovery. By utilizing a SaaS business model, Behaivior aims to democratize mental health recovery and support, assisting users in maintaining their wellness while enabling care providers to enhance their service delivery. Through its proactive approach, Behaivior seeks to improve mental health outcomes and reduce crisis events associated with addiction.

Maxim Biotech

Grant in 2024
Maxim Biotech provides vitro diagnostic testing development and testing solutions.

BetterAge

Grant in 2024
BetterAge is a company dedicated to enhancing the health and well-being of older adults through innovative technology solutions. Founded on the principle that all adults can age well regardless of their current circumstances, BetterAge has developed a digital platform designed exclusively for this demographic. The platform provides personalized, objective content tailored to the needs of older adults, offering education and information about disease risks and actionable insights to support informed decision-making. By fostering a network of experts in aging services, health, and technology, BetterAge aims to create thriving communities where older adults can lead active and healthy lives.

University of Arkansas for Medical Sciences

Grant in 2024
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

RNAConnect

Grant in 2024
RNAConnect specializes in developing enzymatic tools for visualizing and manipulating RNA, with a focus on low-abundance and long, structured RNAs. Their core product is a reverse transcriptase designed to provide greater visibility into these challenging RNA types and their various isoforms. This enzyme is optimized to synthesize cDNA with high fidelity and processivity, enabling researchers to study complex RNA template structures without the need for heat.

University of Arkansas for Medical Sciences

Grant in 2023
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

BioCircuit Technologies

Grant in 2023
BioCircuit Technologies, Inc. is a medical device company based in Atlanta, Georgia, founded in 2016. The company specializes in developing noninvasive electrophysiology devices that monitor, control, and repair peripheral nerves. By utilizing multi-electrode arrays and proprietary algorithms, BioCircuit's products enable clinicians to diagnose health conditions more effectively, track the progression of symptoms over time, and select tailored treatments for individual patients. This innovative approach enhances the ability of healthcare providers to address nerve-related health issues with greater precision and efficiency.

Magnasense

Grant in 2023
Founded in Finland in 2003, Magnasense specializes in developing and manufacturing lateral flow tests for various applications. These include human health, environmental analysis, and veterinary testing. The company's innovative magnetic labeling technique enables quantitative measurements, enhancing reliability and sensitivity. Magnasense offers a Pilot Feasibility test service and operates as a subsidiary of LifeAssays AB.

Base Pair Biotechnologies

Grant in 2023
Base Pair Biotechnologies, Inc. is a biotechnology company based in Pearland, Texas, specializing in the research, development, and discovery of aptamer affinity ligands. Established in 2012, the company offers custom aptamer development services and a catalog of ready-made aptamers. Its innovative platform incorporates novel libraries and proprietary methods for multiplexing the aptamer discovery process, allowing for efficient screening and validation. Base Pair Biotechnologies collaborates with academic, commercial, and government institutions to create advanced tools and technologies across various sectors, including diagnostics, therapeutics, animal testing, agriculture, and environmental testing. The company's expertise in aptamer research, which began in 2004, has positioned it as a leader in the field, enabling clients to obtain high-quality aptamers with reduced time and cost.

Satio

Grant in 2023
Satio develops biotechnology platforms for patch-based blood collection from consumers, using dried blood spots and whole blood samples. The technology enables simple, low-cost, convenient, and painless collection and includes patch portfolios that support potential drug delivery. The company focuses on providing real-time diagnostic and therapeutic insights to global communities, helping individuals act on these insights with confidence.

Strykagen

Grant in 2023
Strykagen manufactures transforming diagnostics and therapeutics for life-threatening rare muscle diseases.

Burst Diagnostics

Grant in 2023
Burst Diagnostics is a company focused on advancing at-home and point-of-care testing through innovative diagnostic solutions. It has developed a rapid antigen diagnostics platform designed to deliver automated laboratory analysis in a user-friendly format. The company specializes in a paper-based testing system that enables immediate deployment from laboratory settings to home use. This system provides comparable sensitivity and specificity to traditional laboratory ELISA tests in an accessible format resembling a lateral flow assay. Burst Diagnostics aims to enhance the capabilities of medical communities, enabling efficient testing for various conditions, including SARS-CoV-2, among others.

Subtle Medical

Grant in 2023
Subtle Medical is a healthcare technology company that develops artificial‑intelligence software for magnetic resonance and positron emission tomography imaging. Its flagship products, SubtleMR and SubtlePET, are FDA‑cleared and CE‑marked tools that enhance image quality by reducing noise and sharpening detail, allowing scans to be performed faster and with lower radiation or contrast dose. The company’s deep‑learning algorithms integrate with any scanner without changing existing workflows, enabling imaging centers and hospitals to increase throughput and improve patient safety. Subtle Medical also offers a vendor‑agnostic AI platform that delivers analytics and support to clinical imaging providers. Founded in 2017 and headquartered in Menlo Park, California, the firm has received an NIH SBIR grant and an RSNA award for its GAD technology.

Buck Institute

Grant in 2023
The Buck Institute is the nation’s first independent research facility focused solely on understanding the connection between aging and chronic disease. Their mission is to increase the healthy years of life. At the Buck Institute, world-class scientists work in a uniquely collaborative environment to understand how normal aging contributes to the development of conditions specifically associated with getting older such as Alzheimer’s and Parkinson’s diseases, cancer, stroke, osteoporosis, heart disease, diabetes, macular degeneration and glaucoma. Their interdisciplinary approach brings scientists from disparate fields together to develop diagnostic tests and treatments to prevent or delay these maladies. The stakes have never been higher. While it’s true that people are living longer, those “extra” years are often marked by disability and pain. In addition to personal hardship, there is also a cost to society. The financial burden of treating the chronic diseases of aging is expected to rise steadily as Baby Boomers get older. There is an urgency to Their mission.

REST Technologies

Grant in 2023
REST Technologies engages in diagnostic sleep testing services.

PediaMetrix

Grant in 2023
PediaMetrix is a pediatric health technology company that develops AI-powered cranial measurement and monitoring tools to detect and manage head shape abnormalities in newborns. Its SoftSpot platform provides quantitative cranial measurements via a smartphone app, enabling at-home and in-office use, and offers data-driven guidance and repositioning instructions for parents. The system also gives pediatricians access to simplified analysis and data from the app to support clinical decisions, and is supported by FDA-cleared digital tools for pediatric head assessment. Founded in 2018, the company is based in Rockville, Maryland, and leverages computer vision and artificial intelligence to lower healthcare costs and improve outcomes in pediatric head care.

Curi Bio

Grant in 2023
Curi Bio is a biotechnology company dedicated to enhancing drug discovery and development through innovative technologies that leverage human stem cells, systems biology, and data analytics. The company aims to streamline the identification and development of new medicines by providing advanced biosystem platforms that integrate human cells and data. Curi Bio's technology offers a range of products designed for cell and tissue engineering, drug discovery, disease modeling, and fundamental cell biology research. By enabling in vivo maturation and alignment of various cell types, the company allows drug developers to conduct more accurate safety and efficacy tests on new drug candidates, ultimately fostering the advancement of next-generation human medicines.

University of Oklahoma - Health Sciences Center

Grant in 2023
University of Oklahoma Health Sciences Center, as a comprehensive academic health center, is to educate students, residents, and other trainees in professional and graduate programs to become Oklahoma’s future team of healthcare leaders, clinicians, researchers, and educators; to advance distinctive basic, translational, clinical, and population research; to innovate and commercialize discoveries; and to deliver exceptional patient care across the full breadth of adult, women’s, and children’s specialties.

Morehouse School of Medicine

Grant in 2023
Founded in 1975, Morehouse School of Medicine is a private medical school located in Atlanta, Georgia. It offers a Doctor of Medicine (MD) program with specializations in Family Medicine, Internal Medicine, Obstetrics and Gynecology, Pediatrics, Psychiatry and Behavioral Sciences, and Surgery. The school also provides master's degrees in Public Health and Biomedical Sciences. Morehouse is committed to educating minority students and reducing health disparities.

Inherent Biosciences

Grant in 2023
Inherent Biosciences is a molecular diagnostics company focused on transforming the traditional trial and error approach in medicine. The company leverages its innovative epigenetic medicine platform to address various health challenges by identifying gene dysregulation and its associated pathways. By translating biological insights into actionable information, Inherent Biosciences aims to enhance treatment strategies for conditions such as pain, infertility, embryo quality, autism, rheumatoid arthritis, psoriatic arthritis, fetal heart disease, and COVID-19. This approach not only guides healthcare professionals in managing complex diseases but also seeks to provide personalized insights that empower patients in their health journeys.

DiagMetrics

Grant in 2023
DiagMetrics is a company that specializes in mask-based diagnostic systems designed to detect respiratory diseases, including Covid-19. Their innovative technology allows for the retrofitting of existing masks to convert breath vapor into a fluid biosample, facilitating non-invasive testing. The system is equipped with Bluetooth capabilities, enabling users to receive test results directly on their smartphones. By providing accessible and efficient diagnostic solutions, DiagMetrics aims to democratize testing and enhance the early detection of respiratory illnesses.

Novel Microdevices

Grant in 2023
Novel Microdevices, LLC is a medical device company that specializes in the development of handheld devices for molecular diagnostics. Founded in 2014 and headquartered in Annapolis, Maryland, the company has created the NOVEL DX device, which employs microfluidics technology to analyze raw biological samples at the point of care. This device delivers results in approximately 30 minutes, allowing healthcare professionals to achieve lab-quality diagnostics without the need for a traditional laboratory setting. Novel Microdevices caters to various sectors, including clinical diagnostics, biodefense, food safety, forensics, drug discovery, animal care, and agriculture, thus addressing a wide range of applications in health and safety.

Access to Advanced Health Institute

Grant in 2023
Access to Advanced Health Institute is a nonprofit biotech research institute that brings together specialists, technologies, and platforms to offer accessible goods and solutions for leveraging the immune system to alleviate disease.

University of Arkansas for Medical Sciences

Grant in 2023
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

CO-DIAGNOSTICS

Grant in 2023
Co-Diagnostics, Inc. is a molecular diagnostics company based in Salt Lake City, Utah, founded in 2013. The company specializes in the development, manufacture, and marketing of advanced diagnostic technologies that focus on the detection and analysis of nucleic acid molecules, such as DNA and RNA. In addition to creating reagents for diagnostic tests, Co-Diagnostics offers self-contained lab systems that incorporate diagnostic equipment from other manufacturers. The company also leverages its proprietary technology to design targeted tests for identifying genetic markers, which can be utilized in various industries beyond infectious diseases, while licensing these tests to specific customers.

Weill Cornell Medicine

Grant in 2023
Weill Cornell Medicine is an outpatient radiology diagnostic center that provides superior imaging and interpretation services.

The University of Texas MD Anderson Cancer Center

Grant in 2023
The University of Texas MD Anderson Cancer Center is a leading institution dedicated exclusively to cancer patient care, research, education, and prevention. Located in the Texas Medical Center in Houston, Texas, it was established as one of the original three comprehensive cancer centers under the National Cancer Act of 1971. MD Anderson serves as both a degree-granting academic institution and a specialized cancer treatment facility. It is affiliated with two prominent medical schools: The University of Texas Medical School at Houston and Baylor College of Medicine. Renowned for its exceptional cancer care, MD Anderson has consistently ranked among the top cancer hospitals in the United States, earning the No. 1 position in U.S. News & World Report's "Best Hospitals" survey for ten of the past twelve years. The center is widely recognized for its commitment to advancing cancer treatment and improving patient outcomes.

University of Alabama at Birmingham

Grant in 2023
The University of Alabama at Birmingham (UAB), established in 1969, is a distinguished institution located in Birmingham, Alabama. It offers a diverse range of over 130 undergraduate and graduate programs, including degrees in the arts, sciences, business, education, engineering, and public health. UAB is particularly renowned for its medical school, which encompasses one of the largest university medical centers in the United States. The university has produced numerous scholars and award recipients, such as Fulbright, Rhodes, and Truman scholars, reflecting the high caliber of its education. Student life at UAB is dynamic, featuring more than 150 student organizations, an active Greek community, and a top-ranking recreation and fitness center, alongside year-round intramural sports. Most students reside in on-campus housing, and UAB provides financial aid and departmental fellowships to support those in need of tuition assistance. Through its commitment to education, research, and community service, UAB addresses both local and global challenges while fostering a culture of discovery and innovation.

Shirley Ryan AbilityLab

Grant in 2023
Shirley Ryan AbilityLab is a translational research hospital. Their services include spinal cord injury recovery, brain injury recovery, COVID recovery, pediatric and adolescent rehabilitation, nursing, cancer rehabilitation, limb loss and impairment, and pain management.

Domus Diagnostics

Grant in 2023
Domus Diagnostics is a healthcare company based in Park City, Utah, founded in 2021. It specializes in providing a care diagnostics platform focused on respiratory disease home testing services. The company's devices are designed for everyday infectious disease testing and support governments and institutions in conducting large-scale testing during new infectious disease outbreaks. This approach aims to facilitate early treatment and prevent the spread of diseases, potentially mitigating pandemic-scale impacts.

University of Alabama at Birmingham

Grant in 2023
The University of Alabama at Birmingham (UAB), established in 1969, is a distinguished institution located in Birmingham, Alabama. It offers a diverse range of over 130 undergraduate and graduate programs, including degrees in the arts, sciences, business, education, engineering, and public health. UAB is particularly renowned for its medical school, which encompasses one of the largest university medical centers in the United States. The university has produced numerous scholars and award recipients, such as Fulbright, Rhodes, and Truman scholars, reflecting the high caliber of its education. Student life at UAB is dynamic, featuring more than 150 student organizations, an active Greek community, and a top-ranking recreation and fitness center, alongside year-round intramural sports. Most students reside in on-campus housing, and UAB provides financial aid and departmental fellowships to support those in need of tuition assistance. Through its commitment to education, research, and community service, UAB addresses both local and global challenges while fostering a culture of discovery and innovation.

Sapphiros

Grant in 2023
Sapphiros is a private equity growth and expansion firm founded in 2021 and based in Massachusetts. The company specializes in investing in growth-stage diagnostic companies, emphasizing innovative and patient-centric technologies. Its portfolio includes a diverse range of capabilities, such as advanced sample collection methods, next-generation diagnostics, computational biology, and printed electronics. By focusing on these areas, Sapphiros aims to enhance the global accessibility of essential diagnostic results for consumers, thereby contributing to advancements in healthcare and diagnostic-related innovations.

Autonomous Medical Devices

Grant in 2023
Sensor-Kinesis Corporation develops innovative medical devices focused on pathogen and virus detection. Founded in 2013 and based in Los Angeles, the company is advancing proprietary biosensor technology that integrates flexible micro biosensor chips with computer systems. These chips are designed to detect specific biomolecules and can be printed on various surfaces, enabling widespread application across multiple industries, including healthcare, food safety, and pharmaceuticals. By linking these sensors to smart devices, users can transmit and analyze biological signals in real time, facilitating improved health monitoring. Sensor-Kinesis aims to empower healthcare professionals and individuals with affordable, portable devices that provide enhanced detection capabilities for diseases and health-related risks, promoting better health outcomes and safety.

Second Sight

Grant in 2023
Founded in 1998, Second Sight is a medical device company dedicated to developing implantable visual prosthetics. Their primary product, the Argus II Retinal Prosthesis System, is designed to provide artificial vision to individuals blinded by outer retinal degenerations such as Retinitis Pigmentosa.

AivoCode

Grant in 2023
AivoCode Inc., established as a biotechnology company, specializes in innovative solutions for critical neurological disorders like traumatic brain injury and neurodegenerative diseases such as Alzheimer's. The company's proprietary technology revolves around unique peptides that selectively target molecular changes in affected brain regions, facilitating the delivery of various therapeutics and diagnostics. These peptides also exhibit intrinsic therapeutic properties. Notably, AivoCode's development has been solely funded through non-dilutive federal grants.

Behaivior

Grant in 2023
Behaivior LLC is a digital health company based in Pittsburgh, Pennsylvania, focused on predicting and preventing addiction relapses through innovative technology. Founded in 2017, Behaivior integrates wearable devices with machine learning algorithms to analyze real-time data from various physiological metrics, such as heart rate and skin temperature. The company’s platform, known as Recovery, employs this data to deliver timely interventions tailored to the needs of individuals in recovery. By utilizing a SaaS business model, Behaivior aims to democratize mental health recovery and support, assisting users in maintaining their wellness while enabling care providers to enhance their service delivery. Through its proactive approach, Behaivior seeks to improve mental health outcomes and reduce crisis events associated with addiction.

MedCognetics

Grant in 2023
MedCognetics is a company that develops advanced artificial intelligence software aimed at enhancing the capabilities of radiologists in cancer detection. Its innovative platform utilizes artificial intelligence and machine learning to identify the earliest manifestations of cancer, particularly in mammography. By streamlining workflow, the technology enables radiologists to prioritize patients with questionable results, thereby improving efficiency and accuracy in diagnosis. The software provides a summarized view of processed case images and highlights areas of concern, facilitating prompt detection and treatment of cancer cells. MedCognetics contributes to reducing breast cancer mortality by enabling earlier identification of the disease.

Chemeleon

Grant in 2023
Chemeleon is a company that has developed an innovative platform technology for rapid and affordable diagnostics capable of detecting a wide array of analytes, including drugs, proteins, and viruses. Their proprietary in vitro diagnostic format delivers a colorimetric readout within minutes, visible to the naked eye, and does not require reagents, instruments, or specialized training. This decentralized testing approach empowers clinicians to extend point-of-care diagnostics and allows individuals to self-administer tests at the point of need. Chemeleon's diagnostics utilize highly selective molecular receptors combined with colorimetric nanomaterial reporters, facilitating immediate and actionable diagnoses that can significantly improve patient outcomes while reducing healthcare costs. Notably, the company developed a diagnostic for detecting beta-2-transferrin, a biomarker for Cerebrospinal Fluid leaks, resulting in substantial reductions in morbidity and healthcare expenses. With a focus on providing specificity and selectivity comparable to lab-based tests but in a fraction of the time and cost, Chemeleon's technology stands to transform healthcare accessibility, especially in resource-limited environments.

Levl

Grant in 2023
Is my medication working? Levl helps you reveal the answer. Levl measures the effectiveness of medications and offers insights to get the most out of mental health treatments. Levl helps people stick to their treatment while supporting clinicians in optimizing the medication.

ActuatedMedical

Grant in 2022
Actuated Medical, Inc. is a medical device company based in Bellefonte, Pennsylvania, that focuses on designing, developing, and manufacturing innovative solutions for healthcare. Established in 2006, the company specializes in devices that facilitate occlusion clearing, tissue penetration, and MRI-guided surgical procedures. Their product line includes systems like TubeClear and NG-Clear, which are designed to clear clogs in feeding tubes, as well as devices for controlled tissue penetration, such as the GentleSharp Device and OsteoAccess System. Additionally, Actuated Medical offers MRI-compatible technologies, including direct drive piezoelectric ultrasonic motors that enhance diagnostic and surgical capabilities during imaging procedures. The company's commitment to improving patient care is reflected in their range of minimally invasive instruments and transdermal delivery systems. Actuated Medical was previously known as Piezo Resonance Innovations, Inc. before rebranding in September 2011.

PharmaJet

Grant in 2022
PharmaJet develops and markets needle-free jet injectors for vaccine delivery, enabling administration without a needle and reducing sharps injuries, needle reuse, cross-contamination, and medical waste. Its Stratis and Tropis platforms are designed to deliver vaccines intramuscular, subcutaneous, or intradermal across various volumes, offering a potential return on investment by lowering risk and waste. Founded in 2005 and based in Golden, Colorado, PharmaJet focuses on delivering safe, user-friendly devices that support immunization programs and aim to simplify injections while expanding access to vaccination.

Linshom

Grant in 2022
Linshom is a healthcare technology company that develops wearable, FDA-cleared sensors for continuous, predictive respiratory monitoring at the patient's bedside or home. Their core product, an operating room quality respiratory profile, enables early detection of respiratory decline, reducing costly rapid response activations and ICU transfers, thereby improving patient outcomes and lowering healthcare costs.

BIOS

Grant in 2022
BIOS Health is a pioneering company focused on developing neural digital therapies by harnessing data-driven insights from the human nervous system. Co-founded by researchers from Cambridge University, the firm aims to revolutionize precision medicine through the identification of neural biomarkers that link nerve activity to various medical conditions. BIOS's innovative approach holds promise for treating chronic diseases such as hypertension, diabetes, rheumatoid arthritis, and neurodegenerative disorders like Parkinson's and Alzheimer's. The company's expertise encompasses a diverse range of fields, including neuroscience, machine learning, software engineering, and biotechnology, allowing it to create advanced solutions for improving the quality of life for individuals suffering from these conditions. Additionally, BIOS is engaged in developing prosthetic connectors that standardize the interface between bionic devices and the body's nervous and soft-tissue systems, enabling enhanced control and feedback for patients with prosthetics.

Sequentify

Grant in 2022
Sequentify develops innovative technology that combines synthetic biology and AI software tools for targeted DNA sequencing applications. These include cancer diagnostics, carrier screening, COVID-19 surveillance, and other genomic research areas.

University of Arkansas for Medical Sciences

Grant in 2022
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Georgia CTSA

Grant in 2022
The Georgia Clinical & Translational Science Alliance (Georgia CTSA) is an inter-institutional magnet that concentrates basic, translational, and clinical research investigators, community clinicians, professional societies, and industry collaborators in dynamic clinical and translational research projects. Emory engaged three of its close academic partners - Morehouse School of Medicine (MSM), Georgia Institute of Technology (Georgia Tech), and the University of Georgia (UGA) - to form the Georgia CTSA. This partnership, a strategic multi-institutional alliance, offers compelling, unique, and synergistic advantages to research and patients statewide. Emory is a national leader in healthcare and biomedical research as well as an outstanding leader in clinical and translational research training and education. Morehouse School of Medicine is a nationally recognized historically black institution that brings ethnic diversity to biomedical research, addresses health disparities through successful community engagement research, and serves as a pipeline for training minority researchers. Georgia Tech is a national leader in biomedical engineering and the application of innovative systems engineering to healthcare solutions. UGA has a proven track record in outstanding basic and translational research and, as the State’s land-grant institution, offers a robust statewide network that enhances community outreach, service, and research. These institutions extend their current partnerships in healthcare, education, and cutting-edge interdisciplinary research to synergize Georgia CTSA. Created in 2017 as one of a national consortium striving to improve the way biomedical research is conducted across the country. The consortium, funded through the National Center for Advancing Translational Sciences, part of the National Institutes of Health's Clinical and Translational Science Awards (CTSA), shares a common vision to translate laboratory discoveries into treatments for patients, engage communities in clinical research efforts and train the next generation of clinical investigators.

Coprata

Grant in 2022
Coprata is a digital health and technology platform that offers innovative solutions for gut health monitoring through hands-free stool sampling and automated bowel movement analysis. By utilizing artificial intelligence and normal toilet usage, the company enables individuals to track their gut health and understand the impact of lifestyle choices, providing early warnings of potential health changes. Coprata's technology focuses on detecting and managing both acute and chronic gastrointestinal diseases while also offering insights into infectious diseases. With an emphasis on non-invasive methods, the platform allows for discreet health monitoring without significantly altering daily routines. The company aims to enhance personalized wellness and explores future applications in preventative health and remote patient monitoring.

Eko Health

Grant in 2022
Eko Health is a leading digital health company advancing how healthcare professionals detect and monitor heart and lung disease with its portfolio of digital stethoscopes, patient and provider software, and AI-powered analysis. Its FDA-cleared platform is used by hundreds of thousands of healthcare professionals worldwide, allowing them to detect earlier and with higher accuracy, diagnose with more confidence, manage treatment effectively, and ultimately give their patients the best care possible. Eko Health is headquartered in Emeryville, California, with over $125 million in funding from Highland Capital Partners, Questa Capital, Artis Ventures, DigiTx Partners, NTTVC, Morningside Technology Ventures Limited, Mayo Clinic, Sutter Health, and others. For more information visit www.ekohealth.com.

Arkana Laboratories

Grant in 2022
Arkana Laboratories offers renal pathology, neuropathology and testing, apol1, and biopharmaceutical services. It is a provider of esoteric pathologic services and a centre for pathology focused on improving care for patients. For inquiries, email, telephone numbers, and physical addresses are available on their website.

Matregenix

Grant in 2022
Matregenix is a MedTech company founded in 2018 by Sherif Soliman and based in Irvine, California. The company specializes in the development and manufacturing of advanced nanofibrous materials for various medical applications. Its flagship product, MatriNova, is a barrier membrane designed specifically for periodontal surgeries, featuring customizable properties such as predictable resorption time and ease of handling. Matregenix employs electrospinning technology to create innovative membrane solutions that cater to the filtration and biomedical sectors. In addition to its product offerings, the company provides comprehensive contract development and manufacturing services, assisting manufacturers in bringing their medical products to market effectively.

PediaMetrix

Grant in 2022
PediaMetrix is a pediatric health technology company that develops AI-powered cranial measurement and monitoring tools to detect and manage head shape abnormalities in newborns. Its SoftSpot platform provides quantitative cranial measurements via a smartphone app, enabling at-home and in-office use, and offers data-driven guidance and repositioning instructions for parents. The system also gives pediatricians access to simplified analysis and data from the app to support clinical decisions, and is supported by FDA-cleared digital tools for pediatric head assessment. Founded in 2018, the company is based in Rockville, Maryland, and leverages computer vision and artificial intelligence to lower healthcare costs and improve outcomes in pediatric head care.

PETcoil

Grant in 2022
Founded in 2018, PETcoil is a medical technology company dedicated to improving healthcare through innovative imaging solutions. With roots tracing back to Stanford University, their core technology enables simultaneous PET and MRI imaging using a radiofrequency-penetrable PET insert system. Their mission is to create affordable, high-performance molecular imaging systems that empower doctors for early and accurate disease diagnosis.

Second Sight

Grant in 2022
Founded in 1998, Second Sight is a medical device company dedicated to developing implantable visual prosthetics. Their primary product, the Argus II Retinal Prosthesis System, is designed to provide artificial vision to individuals blinded by outer retinal degenerations such as Retinitis Pigmentosa.

Aural Analytics

Grant in 2022
Aural Analytics, Inc. is a Scottsdale, Arizona-based company founded in 2015 that specializes in brain health monitoring through innovative technology. The company has developed a multi-modal analytics platform that utilizes artificial intelligence, signal processing, and speech analytics to detect subtle changes in neurological health. By converting smartphones and tablets into effective brain health monitors, Aural Analytics enables the collection of objective and interpretable data. This technology supplements traditional functional rating scales used in clinical trials, providing continuous and reliable metrics for assessing the effectiveness of medical interventions. Aural Analytics' platform captures clinically relevant speech, fine motor, and linguistic samples to offer healthcare professionals accurate assessments of patient health, thereby enhancing the understanding of disease progression.

Reliant Glycosciences

Grant in 2022
Reliant Glycosciences is a biotechnology company dedicated to developing diagnostic and prognostic tools specifically for patients with IgA nephropathy. The company focuses on creating assays that identify biomarkers associated with this condition, which possess diagnostic and prognostic value. By characterizing disease-specific biomarkers, Reliant Glycosciences aims to facilitate the development and testing of innovative, targeted therapies for IgA nephropathy. This approach not only supports the advancement of transformative treatments but also enhances the overall understanding of the disease, ultimately benefiting patients affected by this condition.

Modality.AI

Grant in 2022
Modality.AI, Inc. is a healthcare technology company based in San Francisco, California, founded in 2018. It specializes in AI-powered solutions that enhance the efficiency of clinical trials for neurological and mental health therapies. The company's platform utilizes conversational AI to engage patients through naturalistic spoken interaction, allowing for continuous health assessments anytime and anywhere. By analyzing multimodal data, including audio-visual biomarkers, Modality.AI provides objective measures that correlate with clinical outcomes. This innovative approach enables pharmaceutical companies to conduct self-driven assessments and improve the monitoring of health conditions, ultimately facilitating more effective clinical trials.

Sonavex

Grant in 2022
Sonavex develops imaging technologies for vascular and surgical care, employing ultrasound to detect postoperative blood clots at the point of care and to measure intravascular flow metrics for timely decision making. It also develops bioresorbable, echogenic devices to mark at-risk vessels and to collect data on arteriovenous fistula flow, diameter, and depth at dialysis clinics to assess maturation and anticipate future complications. Based in Baltimore, Maryland, Sonavex focuses on delivering data-driven visualization of vessel health to improve surgical and dialysis patient outcomes.

University of Arkansas for Medical Sciences

Grant in 2022
University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Dascena

Grant in 2022
Dascena, Inc. is a healthcare technology company based in Oakland, California, that specializes in developing machine learning algorithms aimed at enhancing disease detection and improving patient care outcomes. Established in 2018, Dascena's flagship product, AlgoDiagnostics, autonomously processes electronic health record data to facilitate early intervention for conditions such as acute decompensation, sepsis, and acute kidney injury. The company focuses on addressing unmet healthcare needs through its innovative solutions in clinical decision support, point-of-care diagnostics, and biopharma companion diagnostics. By leveraging intensive clinical research, Dascena aims to enable clinical practitioners to make timely and accurate interventions, ultimately saving lives and enhancing the delivery of care.

Enspectra Health

Grant in 2022
Enspectra Health, based in Mountain View, California, develops advanced imaging systems for medical research and diagnosis. Founded in 2012, the company has pioneered the world's first handheld multiphoton imager for human use, capable of visualizing beneath the skin in real-time. Its innovative system combines reflectance confocal and multiphoton laser scanning microscopy to generate multispectral images, enhancing dermatologists' ability to diagnose and treat skin conditions, particularly cancers. Enspectra Health delivers these imaging systems to researchers studying various tissues and has a track record of delivering such systems since its inception.

Arc Bio

Grant in 2022
Arc Bio is a bioscience company specializing in microbial detection through the development of innovative metagenomic next-generation sequencing solutions. The company's platform offers an integrated workflow that streamlines the process from primary sample collection to quantitative results, ensuring fast, precise, and cost-effective analyses. Arc Bio’s tools include advanced software for detecting antimicrobial resistance (AMR) genes, which automates the identification of both pathogens and antibiotic resistance sequences. This capability allows clients to quickly and accurately annotate gram-negative bacterial DNA sequences in under five minutes, enhancing the efficiency and effectiveness of microbial diagnostics.

Epicore Biosystems

Series A in 2022
Epicore Biosystems, Inc. is a Cambridge, Massachusetts-based company that develops and commercializes a proprietary wearable microfluidic sensing platform designed for athletes. Founded in 2017, the company focuses on analyzing small droplets of sweat directly from the skin to measure a range of health and performance metrics. Its technology allows for non-invasive monitoring of sweat biomarkers, skin health, and physiological states in real-time, facilitating personalized management of hydration, nutrition, and overall health. Epicore's innovative platform is grounded in extensive research in microfluidics and soft materials, aiming to enhance athletic performance and health management through accessible and cost-effective solutions.

Subtle Medical

Grant in 2022
Subtle Medical is a healthcare technology company that develops artificial‑intelligence software for magnetic resonance and positron emission tomography imaging. Its flagship products, SubtleMR and SubtlePET, are FDA‑cleared and CE‑marked tools that enhance image quality by reducing noise and sharpening detail, allowing scans to be performed faster and with lower radiation or contrast dose. The company’s deep‑learning algorithms integrate with any scanner without changing existing workflows, enabling imaging centers and hospitals to increase throughput and improve patient safety. Subtle Medical also offers a vendor‑agnostic AI platform that delivers analytics and support to clinical imaging providers. Founded in 2017 and headquartered in Menlo Park, California, the firm has received an NIH SBIR grant and an RSNA award for its GAD technology.

HQ Science

Grant in 2021
HQ Science is a biotechnology company at the forefront of molecular diagnostics innovation.

Inflammatix

Grant in 2021
Inflammatix is a molecular diagnostics company based in Burlingame, California, founded in 2016. It specializes in developing rapid tests that analyze the immune system to address significant clinical and public health issues. The company's initial focus is on creating tests for acute bacterial and viral infections, as well as sepsis, utilizing patent-pending biomarkers exclusively licensed from Stanford University. Inflammatix also builds a diagnostics pipeline based on host response, which includes tests for tropical infections, autoimmune diseases, transplant rejection, and other conditions.

University of Alabama at Birmingham

Grant in 2021
The University of Alabama at Birmingham (UAB), established in 1969, is a distinguished institution located in Birmingham, Alabama. It offers a diverse range of over 130 undergraduate and graduate programs, including degrees in the arts, sciences, business, education, engineering, and public health. UAB is particularly renowned for its medical school, which encompasses one of the largest university medical centers in the United States. The university has produced numerous scholars and award recipients, such as Fulbright, Rhodes, and Truman scholars, reflecting the high caliber of its education. Student life at UAB is dynamic, featuring more than 150 student organizations, an active Greek community, and a top-ranking recreation and fitness center, alongside year-round intramural sports. Most students reside in on-campus housing, and UAB provides financial aid and departmental fellowships to support those in need of tuition assistance. Through its commitment to education, research, and community service, UAB addresses both local and global challenges while fostering a culture of discovery and innovation.

Anavasi Diagnostics

Grant in 2021
Anavasi Diagnostics is a medical technology company specializing in molecular diagnostic testing. The company has developed a clinical diagnostic platform aimed at providing rapid diagnosis of COVID-19. This platform enables the molecular analysis of patient samples in point-of-care settings, utilizing proprietary test kits specifically designed for COVID-19. By offering a rapid and affordable diagnostic solution, Anavasi Diagnostics equips medical personnel with the tools necessary for early detection and diagnosis of the virus, thereby enhancing patient care and response during health crises.

Viora Health

Pre Seed Round in 2021
Viora Health is a health and wellness company focused on advancing health equity among diverse populations. It develops tech-enabled, human-centered programs that utilize social and behavioral engagement to enhance the capacity, satisfaction, outcomes, and revenue for healthcare providers. Viora Health's offerings are designed to improve adherence to diabetes prevention and support patients through online tools that track data and report progress to diabetes prevention programs, facilitating compliance with insurance requirements. Funded by reputable organizations such as the American Heart Association, the National Institutes of Health, Johnson and Johnson, and the National Science Foundation, Viora Health's initiatives have shown significant success, achieving a 75% satisfaction score and double retention rates, while also leading to improved patient outcomes such as reduced stress, increased social support, and better access to food.

SeLux Diagnostics

Grant in 2021
SeLux Diagnostics, Inc. is a biotechnology company based in Charlestown, Massachusetts, focused on developing a next-generation phenotyping platform for antibiotic susceptibility testing and diagnostics of infectious diseases. Established in 2014, the company utilizes synthetic amplifier technology to enhance the speed and complexity of antibiotic susceptibility testing, thereby significantly improving patient care. By facilitating the rapid selection of personalized antimicrobial therapies, SeLux aims to transform the management of infectious diseases, ultimately saving lives, reducing hospital stays, and combating the growing issue of antibiotic resistance through more targeted treatments.

Chosen Diagnostics

Grant in 2021
Chosen Diagnostics is a developer of innovative biomarker diagnostic kits designed to enhance healthcare delivery for neonates. The company's primary focus is on diagnosing a prevalent and life-threatening bowel disease in preterm infants. Its diagnostic kit provides more accurate results compared to existing options, facilitating earlier medical intervention. By enabling healthcare professionals to detect critical conditions sooner, Chosen Diagnostics aims to improve treatment outcomes for thousands of low birth weight preterm infants, ultimately contributing to better health and survival rates in this vulnerable population.

Amplo Biotechnology

Grant in 2021
Amplo Biotechnology is a biopharmaceutical company focused on developing innovative Adeno-Associated Viral (AAV) therapies aimed at treating defects related to the neuromuscular junction. These defects can lead to severe health issues, including paralysis and difficulties with breathing and swallowing. The company's lead program, AAV-Dok7, was created by Professor Yuji Yamanashi's research team at the Institute of Medical Science at the University of Tokyo, and it holds promise for addressing various congenital myasthenic syndromes and other rare, severe diseases. Amplo's therapies are administered through intravascular injection, which initiates specific molecular events necessary for effective treatment, thereby enhancing the potential for curative outcomes in affected patients.

Benten Technologies

Grant in 2021
Benten Technologies is a social impact company dedicated to democratizing healthcare through digital therapeutics. With approximately $9 million in non-dilutive funding, the company is developing a pipeline of innovative healthcare solutions aimed at improving access to medical services. In addition to its focus on healthcare, Benten Technologies offers technology consulting services, including application development, management consulting, quality assurance, and research and development. By leveraging proven system integration methodologies and expertise, the company aims to deliver value-driven business solutions that enhance operational efficiency for various organizations.

Nemours

Grant in 2021
The Nemours Foundation is a non-profit organization established in 1936 and headquartered in Jacksonville, Florida. Its mission is to enhance the health and well-being of children globally by providing high-quality care and programs that are often not readily accessible, regardless of a family's financial situation. The foundation focuses on leadership and innovative services aimed at restoring and improving children's health. Its assets are managed by a board of directors, ensuring a commitment to excellence and distinction in all initiatives. Through its various programs and services, the Nemours Foundation strives to make a significant impact on pediatric health.

Nanoscope Therapeutics

Grant in 2021
Nanoscope Therapeutics Inc. is a biotechnology company based in Bedford, Texas, focused on developing innovative gene therapies aimed at restoring vision for individuals affected by retinal degenerative diseases, such as retinitis pigmentosa and dry age-related macular degeneration. Established in 2017, the company specializes in light-sensitive molecules and employs light-assisted gene delivery techniques to enable targeted treatment that re-sensitizes the retina, allowing patients to perceive low light levels. By utilizing a unique optogenetic approach, Nanoscope Therapeutics aims to deliver a solution for vision loss in patients where no effective cure currently exists, thereby advancing the potential for vision restoration in millions of affected individuals.

Hesperos

Grant in 2021
Hesperos, Inc. specializes in the development of Human-on-a-Chip microfluidic systems aimed at transforming toxicology testing and drug discovery efficacy evaluations. Founded by Michael L. Shuler and James J. Hickman, the company has pioneered advancements in creating individual organ-on-a-chip constructs and interconnected multi-organ systems. Hesperos's innovative pumpless platforms utilize serum-free cellular mediums to facilitate communication between multiple organ systems. The systems also incorporate integrated computational pharmacokinetics and pharmacodynamics modeling to assess live physiological responses through functional readouts from various tissues, including neurons, cardiac, muscle, and barrier tissues, as well as responses from the liver and pancreas. This technology enables clients to predict in vivo functions without relying on animal models, marking a significant step forward in biomedical research and development.

ID Genomics

Grant in 2021
ID Genomics is a company that focuses on nucleotide sequence-based molecular diagnostics and the epidemiological analysis of microbial pathogens. It offers rapid and high-resolution clonal identification services tailored for clinical microbiology, research laboratories, and academia. Utilizing advanced techniques such as expanded multi-locus sequence typing (MLST) and genome-wide polymorphism annotation, the company creates customized phylogenetic and genomic analyses alongside comprehensive databases. ID Genomics also develops a genomics bar-coding-based diagnostic system that integrates molecular diagnostics with epidemiological surveillance and big-data tools. This system aids healthcare providers in accurately matching infectious agents with appropriate antibiotic treatments, enabling personalized medical care for patients with infectious diseases, often before they leave the clinic.

Helixbind

Grant in 2021
Helixbind is a biotechnology company based in Worcester, Massachusetts. Founded in 2012, it specializes in developing a pathogen identification platform designed to rapidly detect and identify bloodstream infections directly from whole blood specimens, enabling timely targeted antimicrobial interventions.

Inso Biosciences

Grant in 2021
Inso Biosciences is an early-stage biotechnology company focused on developing innovative hardware platforms and tools for genomic sample handling. Utilizing patented microfluidic technology originally invented at Cornell University, Inso Biosciences enhances the efficiency of processing cellular material. The company's platform is designed to facilitate genomic analysis, including applications in long-read DNA extraction, multiomic sample processing, and pathogen surveillance. By enabling healthcare and biotechnology companies to effectively separate and isolate cellular components, Inso Biosciences aims to transform the landscape of biological sample preparation.

Enspectra Health

Grant in 2021
Enspectra Health, based in Mountain View, California, develops advanced imaging systems for medical research and diagnosis. Founded in 2012, the company has pioneered the world's first handheld multiphoton imager for human use, capable of visualizing beneath the skin in real-time. Its innovative system combines reflectance confocal and multiphoton laser scanning microscopy to generate multispectral images, enhancing dermatologists' ability to diagnose and treat skin conditions, particularly cancers. Enspectra Health delivers these imaging systems to researchers studying various tissues and has a track record of delivering such systems since its inception.

AvantGen

Grant in 2021
AvantGen is a biotechnology company based in San Diego, established in 2006, that specializes in the discovery and optimization of therapeutic antibodies. The company operates two divisions: Therapeutic and Research & Diagnostic. Its Therapeutic Division focuses on novel human antibody discovery, humanization, and affinity maturation, utilizing its proprietary yeast display system and a comprehensive database of natural human antibodies. AvantGen offers a range of advanced technologies, including fully human antibody libraries and cell engager technology, to support pharmaceutical and biotechnology companies in their therapeutic development efforts. By providing services, establishing partnerships, and offering licensing opportunities, AvantGen aims to expedite the process of bringing antibody-based therapies to market.

BioCircuit Technologies

Grant in 2021
BioCircuit Technologies, Inc. is a medical device company based in Atlanta, Georgia, founded in 2016. The company specializes in developing noninvasive electrophysiology devices that monitor, control, and repair peripheral nerves. By utilizing multi-electrode arrays and proprietary algorithms, BioCircuit's products enable clinicians to diagnose health conditions more effectively, track the progression of symptoms over time, and select tailored treatments for individual patients. This innovative approach enhances the ability of healthcare providers to address nerve-related health issues with greater precision and efficiency.

CaroGen

Grant in 2021
CaroGen Corporation is a biopharmaceutical company based in Farmington, Connecticut, founded in 2012. The company specializes in developing recombinant and replication proficient virus-like vesicle (VLV) technology for the creation of vaccines targeting infectious and chronic diseases. CaroGen's innovative platform, developed by Professor John Rose at Yale University School of Medicine, enables the delivery of genes for various therapeutic proteins, including antigens and cytokines. The company is actively advancing a portfolio of vaccine candidates addressing significant viral agents such as hepatitis B, hepatitis C, and influenza, among others. By focusing on immunotherapy approaches, CaroGen aims to enhance treatment efficacy against a broad array of diseases.

Xtrava Health

Grant in 2021
Xtrava Health, established in 2014 and headquartered in Santa Clara, California, specializes in developing contactless bio-sensing technology for health and wellness applications. The company's flagship product, Butterfly, is a wearable child wellness monitor that automatically tracks vital signs, sleep patterns, feeding, diaper changes, and activities, providing parents with comprehensive insights. Xtrava Health also develops and commercializes simple, accurate, and affordable diagnostic products for both professional and at-home use, focusing on respiratory health, employee wellness, and baby monitoring.
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