The National Institutes of Health (NIH) is a leading biomedical research facility in the United States, operating under the Department of Health and Human Services. Established in 1887 and based in Bethesda, Maryland, NIH is the primary agency responsible for biomedical and health-related research in the country. It comprises 27 separate institutes and centers, each focusing on different disciplines within biomedical science. NIH conducts its own scientific research through the Intramural Research Program and provides significant funding for research at external institutions via the Extramural Research Program. With a workforce that includes 1,200 principal investigators and over 4,000 postdoctoral fellows, NIH has been instrumental in major medical breakthroughs, such as the development of vaccines for hepatitis and human papillomavirus, as well as the discovery of treatments for various health conditions. As the world's largest source of medical research funding, NIH continues to advance scientific knowledge and contribute to public health improvements.
Ramona develops advanced microscopy tools designed to enhance cellular-level research by capturing detailed images over vast areas. The company's innovative microscope employs custom control electronics to efficiently process large volumes of image data from multiple micro-cameras, allowing researchers to capture and analyze extensive gigapixel datasets. This capability not only provides a wider field of view but also enables synchronous data capture, allowing for real-time observation of cellular processes. By offering a new perspective on cellular dynamics, Ramona's technology empowers researchers to make more informed decisions quickly and effectively.
Modality.AI
Grant in 2022
Modality.AI, Inc. specializes in AI-driven healthcare screening solutions that focus on monitoring and assessing patients' health through conversational interactions. The company's platform utilizes audio-visual biomarkers and engages patients via dialogue and video to provide continuous health assessments. This technology is particularly beneficial for pharmaceutical companies, as it enhances the efficiency of clinical trials for therapies targeting neurological and mental health conditions. By analyzing multimodal data, Modality.AI delivers objective measures that correlate with clinical outcomes, facilitating self-driven neurological assessments. Founded in 2018 and headquartered in San Francisco, California, Modality.AI aims to improve health evaluations and streamline the clinical trial process.
Enspectra Health
Grant in 2022
Enspectra Health, based in Mountain View, California, specializes in developing advanced imaging systems for medical applications. The company has created the first hand-held multiphoton imager for human use, enabling real-time imaging of live cellular anatomy beneath the skin. Its innovative device combines reflectance confocal and multiphoton laser scanning microscopy to produce multispectral images that reveal details not visible to the naked eye. This technology aids researchers and dermatologists in examining the structure and function of various tissues, including muscle, tendon, cartilage, and skin, thereby enhancing the diagnosis and treatment of skin conditions, particularly skin cancers. Enspectra Health aims to simplify the evaluation process for physicians and improve patient outcomes through its cutting-edge imaging solutions.
Ramona
Grant in 2021
Ramona develops advanced microscopy tools designed to enhance cellular-level research by capturing detailed images over vast areas. The company's innovative microscope employs custom control electronics to efficiently process large volumes of image data from multiple micro-cameras, allowing researchers to capture and analyze extensive gigapixel datasets. This capability not only provides a wider field of view but also enables synchronous data capture, allowing for real-time observation of cellular processes. By offering a new perspective on cellular dynamics, Ramona's technology empowers researchers to make more informed decisions quickly and effectively.
Enspectra Health
Grant in 2021
Enspectra Health, based in Mountain View, California, specializes in developing advanced imaging systems for medical applications. The company has created the first hand-held multiphoton imager for human use, enabling real-time imaging of live cellular anatomy beneath the skin. Its innovative device combines reflectance confocal and multiphoton laser scanning microscopy to produce multispectral images that reveal details not visible to the naked eye. This technology aids researchers and dermatologists in examining the structure and function of various tissues, including muscle, tendon, cartilage, and skin, thereby enhancing the diagnosis and treatment of skin conditions, particularly skin cancers. Enspectra Health aims to simplify the evaluation process for physicians and improve patient outcomes through its cutting-edge imaging solutions.
Visikol
Grant in 2021
Visikol Inc. is a company based in New Brunswick, New Jersey, specializing in advanced drug discovery services and bio-imaging technology. It develops and provides a range of products, including Visikol, an optical sectioning tool for plant tissues, and Visikol HISTO, a series of tissue clearing kits and reagents designed to enhance 3D imaging in tissue processing workflows. Visikol's technologies enable researchers to visualize specimens effectively, allowing for the identification of adulterants and assessment of sample quality. The company also offers comprehensive drug discovery services, including the development of 2D and 3D in vitro models, assays, and digital pathology solutions. By transforming tissues into high-resolution images and quantitative datasets, Visikol supports clients in making informed decisions during the drug discovery process. Additionally, the firm manufactures 3D immuno-labeling kits, facilitating rapid imaging of whole tissues and 3D cell culture models, thereby moving beyond traditional 2D sectioning methods.
MRIMath
Grant in 2021
MRIMath specializes in medical imaging technology aimed at improving cancer diagnosis and treatment. The company develops solutions that assist oncologists and surgeons in identifying tumors and assessing treatment responses, thereby enhancing patient outcomes in oncology. MRIMath's innovative approach incorporates an interactive human-AI interface that offers a reliable and cost-effective tool for medical practitioners to monitor brain tumor growth. Beyond its imaging technology, MRIMath also provides hospital care, medical device services, and AI consulting, along with AI-powered software designed to streamline healthcare processes.
Xoran Technologies
Grant in 2019
Xoran Technologies, LLC is a manufacturer of advanced computed tomography (CT) imaging solutions designed for immediate diagnosis at the point of care. Based in Ann Arbor, Michigan, the company provides a range of products, including the MiniCAT for high-resolution imaging of sinuses and temporal bones, and the Xoran xCAT, a mobile cone beam CT system that captures high-resolution three-dimensional images. Xoran Technologies also offers LuminX digital radiography systems, including overhead robotic suites and various floor-mounted and mobile options. Founded in 2001, the company is dedicated to enhancing patient care by delivering innovative imaging technologies that facilitate accurate diagnoses while minimizing radiation exposure.
Ramona
Grant in 2019
Ramona develops advanced microscopy tools designed to enhance cellular-level research by capturing detailed images over vast areas. The company's innovative microscope employs custom control electronics to efficiently process large volumes of image data from multiple micro-cameras, allowing researchers to capture and analyze extensive gigapixel datasets. This capability not only provides a wider field of view but also enables synchronous data capture, allowing for real-time observation of cellular processes. By offering a new perspective on cellular dynamics, Ramona's technology empowers researchers to make more informed decisions quickly and effectively.
Visikol
Grant in 2019
Visikol Inc. is a company based in New Brunswick, New Jersey, specializing in advanced drug discovery services and bio-imaging technology. It develops and provides a range of products, including Visikol, an optical sectioning tool for plant tissues, and Visikol HISTO, a series of tissue clearing kits and reagents designed to enhance 3D imaging in tissue processing workflows. Visikol's technologies enable researchers to visualize specimens effectively, allowing for the identification of adulterants and assessment of sample quality. The company also offers comprehensive drug discovery services, including the development of 2D and 3D in vitro models, assays, and digital pathology solutions. By transforming tissues into high-resolution images and quantitative datasets, Visikol supports clients in making informed decisions during the drug discovery process. Additionally, the firm manufactures 3D immuno-labeling kits, facilitating rapid imaging of whole tissues and 3D cell culture models, thereby moving beyond traditional 2D sectioning methods.
Ramona
Grant in 2018
Ramona develops advanced microscopy tools designed to enhance cellular-level research by capturing detailed images over vast areas. The company's innovative microscope employs custom control electronics to efficiently process large volumes of image data from multiple micro-cameras, allowing researchers to capture and analyze extensive gigapixel datasets. This capability not only provides a wider field of view but also enables synchronous data capture, allowing for real-time observation of cellular processes. By offering a new perspective on cellular dynamics, Ramona's technology empowers researchers to make more informed decisions quickly and effectively.
VisionQuest Biomedical
Grant in 2018
VisionQuest Biomedical is a medical device company focused on leveraging artificial intelligence to prevent avoidable blindness. The company's flagship software application, EyeStar, aids in the diagnosis of diabetic retinopathy, while another application, Aspire, is designed to detect malarial retinopathy. Expanding its technological scope, VisionQuest has introduced i-RxTherm, which aims to identify early-stage diabetic diseases beyond ocular conditions. VisionQuest develops innovative image-based technologies to improve healthcare accessibility, particularly in diabetes and eye care, benefiting millions in the United States and globally. Their solutions enhance digital binocular indirect ophthalmoscopy examinations and utilize a neural network for effective analysis of retinal images captured with smartphone-based cameras, facilitating early detection of diabetic peripheral neuropathy and retinopathy of prematurity in various healthcare settings.
Perceptive Navigation
Grant in 2018
Perceptive Navigation LLC is a pre-clinical stage medical device company based in Baltimore, Maryland, focused on developing interventional medical devices for image-guided surgery. Its flagship product, Vu-Path, is an innovative intracorporeal ultrasound device that combines forward-viewing ultrasound imaging with a working portal for the introduction of needles, biopsy instruments, guide wires, and therapeutic delivery. Designed to enhance the safety and efficacy of minimally invasive procedures across various medical specialties, including radiology, cardiology, interventional oncology, and urology, Vu-Path addresses critical limitations of existing imaging techniques, which can be costly, cumbersome, and risky. The device aims to provide accurate and precise access to internal structures, thereby reducing procedural times and enhancing overall patient care. By replacing traditional imaging methods like surface ultrasound, CT, X-Ray, and MRI, Vu-Path is positioned to streamline complex surgical operations while minimizing resource requirements. Perceptive Navigation was incorporated in 2012 and continues to advance its technology to meet the needs of the medical community.
Modulim
Grant in 2017
Modulim is a leader in light-based imaging technology focused on tissue and vascular assessment through spatial frequency domain imaging (SFDI). The company has developed the Clarifi Imaging System, which aids clinicians in identifying patients at risk for complications such as diabetic foot ulcers and amputations due to compromised circulation. By enabling timely interventions, this technology plays a crucial role in preserving patients' limbs and lives. Additionally, Modulim's devices are applicable in research, aesthetics, and medicine, providing professionals with transformative tools for the prevention, diagnosis, and treatment of various medical skin conditions.
Ramona
Grant in 2017
Ramona develops advanced microscopy tools designed to enhance cellular-level research by capturing detailed images over vast areas. The company's innovative microscope employs custom control electronics to efficiently process large volumes of image data from multiple micro-cameras, allowing researchers to capture and analyze extensive gigapixel datasets. This capability not only provides a wider field of view but also enables synchronous data capture, allowing for real-time observation of cellular processes. By offering a new perspective on cellular dynamics, Ramona's technology empowers researchers to make more informed decisions quickly and effectively.
VisionQuest Biomedical
Grant in 2016
VisionQuest Biomedical is a medical device company focused on leveraging artificial intelligence to prevent avoidable blindness. The company's flagship software application, EyeStar, aids in the diagnosis of diabetic retinopathy, while another application, Aspire, is designed to detect malarial retinopathy. Expanding its technological scope, VisionQuest has introduced i-RxTherm, which aims to identify early-stage diabetic diseases beyond ocular conditions. VisionQuest develops innovative image-based technologies to improve healthcare accessibility, particularly in diabetes and eye care, benefiting millions in the United States and globally. Their solutions enhance digital binocular indirect ophthalmoscopy examinations and utilize a neural network for effective analysis of retinal images captured with smartphone-based cameras, facilitating early detection of diabetic peripheral neuropathy and retinopathy of prematurity in various healthcare settings.
VisionQuest Biomedical
Grant in 2015
VisionQuest Biomedical is a medical device company focused on leveraging artificial intelligence to prevent avoidable blindness. The company's flagship software application, EyeStar, aids in the diagnosis of diabetic retinopathy, while another application, Aspire, is designed to detect malarial retinopathy. Expanding its technological scope, VisionQuest has introduced i-RxTherm, which aims to identify early-stage diabetic diseases beyond ocular conditions. VisionQuest develops innovative image-based technologies to improve healthcare accessibility, particularly in diabetes and eye care, benefiting millions in the United States and globally. Their solutions enhance digital binocular indirect ophthalmoscopy examinations and utilize a neural network for effective analysis of retinal images captured with smartphone-based cameras, facilitating early detection of diabetic peripheral neuropathy and retinopathy of prematurity in various healthcare settings.
VisionQuest Biomedical
Grant in 2015
VisionQuest Biomedical is a medical device company focused on leveraging artificial intelligence to prevent avoidable blindness. The company's flagship software application, EyeStar, aids in the diagnosis of diabetic retinopathy, while another application, Aspire, is designed to detect malarial retinopathy. Expanding its technological scope, VisionQuest has introduced i-RxTherm, which aims to identify early-stage diabetic diseases beyond ocular conditions. VisionQuest develops innovative image-based technologies to improve healthcare accessibility, particularly in diabetes and eye care, benefiting millions in the United States and globally. Their solutions enhance digital binocular indirect ophthalmoscopy examinations and utilize a neural network for effective analysis of retinal images captured with smartphone-based cameras, facilitating early detection of diabetic peripheral neuropathy and retinopathy of prematurity in various healthcare settings.
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