National Institutes of Health

SonoMotion Inc. is a medical device company focused on developing non-invasive solutions for kidney stone disease. Founded in 2012 and based in San Mateo, California, the company offers innovative products such as Break Wave, which safely fragments large kidney stones, and Stone Clear, which aids in clearing the resulting stone fragments within 15 minutes in an office setting, without the need for general anesthesia or X-ray radiation. SonoMotion is actively involved in advancing its technology, with a stone repositioning solution currently undergoing clinical trials and a second-generation stone-breaking technology in development. The company's mission is to provide effective and cost-efficient treatments for kidney stone patients.

Neuronoff, a medical device company, is focused on the development of the Injectrode™, a novel injectable metal electrode, which is deployed via a small needle for manufacturing the neuromodulation interface inside the body on a variety of anatomical targets.

IVOS Medical is an innovative medical device company focused on advancing airway management technology.

Rhealth is a biotechnology company that focuses on delivering advanced health management solutions through an AI-driven platform tailored for hospitals. It aims to enhance the accessibility of analytical and diagnostic information for both physicians and patients. By integrating portable diagnostic and monitoring technologies, Rhealth seeks to transform the way health information is accessed and utilized, ultimately enabling healthcare providers to deliver more timely and effective care.

University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

BioCircuit Technologies, Inc. is a medical device company based in Atlanta, Georgia, founded in 2016. The company specializes in the development of noninvasive electrophysiology devices aimed at monitoring, controlling, and repairing peripheral nerves. By utilizing multi-electrode arrays and proprietary algorithms, BioCircuit's products enable clinicians to diagnose health conditions at an earlier stage, track the progression of symptoms over time, and select more precise treatments tailored to individual patients' needs. This innovative approach enhances the ability of healthcare providers to address nerve-related issues effectively.

BMI OrganBank specializes in the development of advanced medical devices and perfusion technology aimed at enhancing the preservation of organs and tissues for transplantation. By collaborating with academic institutions, the company seeks to expand the potential of organ transplantation and improve patient outcomes. Its focus includes innovative solutions that could significantly transform kidney transplantation and other organ preservation methods, ultimately benefiting thousands of patients in need of transplants. The company’s efforts also extend to developing technologies for organ preservation, such as lung ventilators and ex vivo tissue perfusion, which enable healthcare providers to deliver better medical care.

Novel Microdevices, LLC is focused on developing handheld devices for molecular diagnostics, specifically through its product, NOVEL DX. This innovative device utilizes microfluidics technology to analyze raw biological samples directly at the point of care, providing results in just 30 minutes. By enabling healthcare professionals to achieve lab-quality results without the need for a traditional laboratory setting, the device addresses various sectors including clinical diagnostics, biodefense, food safety, forensics, drug discovery, animal care, and agriculture. Founded in 2014 by Andrea Pais, Novel Microdevices is headquartered in Baltimore, Maryland.

Young Heart Valve is a Polymeric, Hyaluronan-Enhanced Transcatheter Aortic Valves which were developed by engineers with inspiration from nature. The future of heart valve intervention is being altered by Young Heart Valve. Animal tissue is no longer required thanks to Young Heart Valve. Hyaluronan is included into the leaflets of Young Heart Valve's RejuvenateTM TAVR device, forming a biomolecular interpenetrated network that has been shown to be resistant to calcification and thrombosis.

Caretaker Medical, LLC specializes in developing and manufacturing wireless patient monitoring devices. Its flagship product, CareTaker, is a wearable system that allows for continuous monitoring of vital signs, including blood pressure, heart rate, respiration rate, and other hemodynamic parameters, using a simple finger cuff. The device features integrated multi-mode radios for secure data transmission over cellular networks or Bluetooth, enabling healthcare providers to easily monitor patients' vital signs via a tablet or connected nurse station. Founded in 2014 and headquartered in Charlottesville, Virginia, with additional offices in Surrey, UK, and Beijing, China, Caretaker Medical aims to enhance patient outcomes and streamline care delivery across various healthcare settings, from hospitals to post-discharge environments.

Teal Health is dedicated to improving women's health by providing at-home cervical cancer screenings. The company has developed an FDA-approved device that allows women to perform these essential screenings in the comfort and privacy of their own homes. By simplifying the process, Teal Health aims to encourage timely screenings, which are crucial for early detection and treatment, ultimately striving to eradicate cervical cancer in the United States. The initiative is supported by a group of committed investors who share the vision of transforming women's health experiences.

Resvita Bio is engaged in the development and manufacturing of engineered probiotics aimed at treating skin-related diseases, including chronic conditions and cancer. The company focuses on creating a versatile skin microbial platform utilizing synthetic biology and metabolic engineering. This innovative approach allows for the continuous delivery of therapies that alleviate inflammation, promote tissue regeneration, and eliminate harmful bacteria. By leveraging this technology, Resvita Bio aims to offer faster and more efficient treatment alternatives for individuals suffering from chronic skin diseases.

Lasarrus is a Baltimore-based company founded in 2013 that specializes in developing wearable devices for patients with chronic obstructive pulmonary disease (COPD). The company's innovative device is designed to enhance physical therapy by facilitating telemedicine and remote monitoring. It captures physiological and range-of-motion data, allowing patients to track their health routines effectively. Lasarrus aims to provide an affordable, comfortable, and non-invasive solution that accelerates recovery for users, improving their overall health management.

Subtle Medical, Inc. is a healthcare technology company based in Menlo Park, California, that specializes in developing AI-powered medical imaging software for clinical imaging centers and hospitals. Founded in 2017, the company offers products such as SubtleMR and SubtlePET, both of which are FDA cleared and CE marked. These technologies enhance image quality in magnetic resonance imaging (MRI) and positron emission tomography (PET) exams by reducing noise and increasing sharpness, ultimately improving workflow efficiency while ensuring patient safety. Subtle Medical also features SubtleGAD, a technology recognized by the Radiological Society of North America, which aims to make imaging exams safer. The company employs a vendor-agnostic AI infrastructure that integrates seamlessly with existing scanners, allowing imaging providers to serve more patients effectively by enhancing image acquisition without disrupting their current workflow. Through its innovations, Subtle Medical seeks to improve the quality, value, and accessibility of medical imaging while significantly lowering costs and radiation exposure.

Penderia Technologies is a medical device company focused on innovative orthopedic solutions. It develops implantable, battery-less sensors for monitoring injury and healing progress in real-time, enabling personalized rehabilitation therapies.

University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

VenoStent, Inc. is a clinical-stage tissue engineering company based in Nashville, Tennessee, with an additional office in Houston, Texas. Founded in 2017, it specializes in the development of bioresorbable smart polymers designed to enhance vascular surgery outcomes. The company’s primary product, SelfWrap, is a perivascular wrap that functions as an external stent, providing mechanical support to veins and promoting outward growth. This innovative technology aims to reduce complications at the vein-artery junction in dialysis patients, particularly by minimizing vein collapse and improving the usability of arteriovenous fistulas (AVF). By utilizing a new class of shape-memory polymers that do not require sutures, VenoStent's approach reduces surgery time and lowers the risk of infection, ultimately enhancing the quality and length of life for patients with chronic kidney disease undergoing hemodialysis.

University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Annoviant is a healthcare company focused on the development of innovative medical devices, specifically tissue-based valve and conduit replacement products. These devices are designed to replace or repair structures that are congenitally absent or underdeveloped. Annoviant's offerings are characterized by their regenerative capabilities and resistance to thrombosis, calcification, and infection. By maintaining essential mechanical properties, these devices aim to enhance clinical outcomes for substitute conduit arteries in infants and children, ultimately reducing the need for repeated surgical interventions.

Cincinnati Children’s Hospital Medical Center is a leading institution dedicated to improving child health, attracting patients and families both regionally and internationally. Recognized for its expertise, the hospital serves as a referral center for complex surgical procedures and treatments for rare pediatric diseases. The center is committed to advancing pediatric medicine by discovering innovative and effective treatment methods, solidifying its reputation as one of the foremost facilities for pediatric care globally.

Phase provides 3D-printing medical devices for microfluidics. Phase’s proprietary platform enables PDMS (Sylgard 184) to be 3D printed at a scale and resolution that was previously unattainable.

University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Amydis is a privately-held pharmaceutical company focused on developing innovative diagnostic solutions for diseases associated with amyloid proteins. The company aims to create a universal, non-invasive diagnostic tool that is faster, more accessible, and affordable than existing tests for conditions with unmet clinical needs. Amydis has developed a platform of novel compounds that fluoresce upon binding to amyloid proteins, facilitating the diagnosis of various diseases. Its primary focus is on the early detection of Alzheimer's disease, but it also explores potential applications for detecting Parkinson’s disease, Creutzfeldt-Jakob disease, Pre-eclampsia, TTR Amyloidosis, and Cerebral Amyloid Angiopathy. By providing diagnostic capabilities for amyloid-associated diseases, Amydis empowers patients and healthcare professionals to make informed decisions about health risks.

Virtuoso Surgical focuses on developing robotic tools specifically for minimally invasive endoscopic surgery. The company's surgical system features needle-sized robotic arms that allow surgeons to navigate and operate in hard-to-reach areas of the body, addressing limitations posed by traditional endoscopes. By providing dexterous and accurate instruments, Virtuoso Surgical aims to enhance surgical precision and improve patient outcomes while also offering a cost-effective solution for healthcare providers.

On average, we spend a third of our lives in bed. Our self-positioning bed; the Korus™, combined with our AI-driven software, is designed to provide precise sleep therapies improving lifestyle and medical care that benefits sleep wellness and faster recovery at home.

Endomimetics is focused on developing advanced bio-nanometric coating technology aimed at enhancing medical care for patients with kidney diseases. The company's innovative stent coating technology is designed to closely mimic human tissue, which helps to minimize the need for additional surgeries and improves the longevity of the devices. By reducing complications associated with the implantation of foreign materials, Endomimetics' technology aims to provide better outcomes for patients, ultimately improving their overall quality of care in the management of kidney-related health issues.

Rivanna Medical, LLC is a medical technology company based in Charlottesville, Virginia, founded in 2010. The company focuses on developing and commercializing innovative ultrasound-based systems aimed at enhancing the application of spinal and epidural anesthesia through advanced 3D navigation of the lumbar spine. Its flagship product, Accuro, not only facilitates precise anesthesia delivery but also supports various diagnostic imaging needs, including musculoskeletal and abdominal anatomies. Rivanna Medical is committed to improving patient outcomes and lowering healthcare costs while minimizing patient exposure to radiation commonly associated with X-ray-based imaging techniques.

RevBio is focused on developing innovative bone repair technology through its flagship product, Tetranite, which is an injectable, self-setting, osteoconductive bone adhesive biomaterial. This synthetic adhesive is designed to bond bone to bone and bone to metal in wet environments and is currently under FDA review for various applications in oral, craniofacial, orthopedic, and neurosurgical fields. Tetranite biodegrades over time, being replaced by new bone as part of the natural bone remodeling process, and serves as a scaffold to facilitate bone growth. By reducing the duration and complexity of medical procedures, RevBio's technology enables more minimally invasive surgeries and aims to improve patient outcomes by decreasing recovery time, pain, and overall costs associated with care. The company is building a diverse portfolio of applications within both dental and orthopedic markets.

BioCircuit Technologies, Inc. is a medical device company based in Atlanta, Georgia, founded in 2016. The company specializes in the development of noninvasive electrophysiology devices aimed at monitoring, controlling, and repairing peripheral nerves. By utilizing multi-electrode arrays and proprietary algorithms, BioCircuit's products enable clinicians to diagnose health conditions at an earlier stage, track the progression of symptoms over time, and select more precise treatments tailored to individual patients' needs. This innovative approach enhances the ability of healthcare providers to address nerve-related issues effectively.

Rhaeos is a pioneering company that has developed the first wearable shunt monitor to enhance care for patients with hydrocephalus. Utilizing a novel thermal biosensor, the device allows for noninvasive, real-time monitoring of cerebrospinal fluid flow. This innovative technology, born from collaborative research at Northwestern University involving experts from engineering, medicine, and management, addresses a significant clinical need by providing timely data to improve treatment for chronic medical conditions. Rhaeos's patches are designed to detect fluid flow in various bodily systems, including blood and lymph, facilitating quicker medical responses and advancing the standard of care in neurosurgery and beyond.

AegirBio AB is a Swedish diagnostics company focused on developing innovative home testing solutions for oral health, therapeutic drug monitoring, and infectious diseases. The company has established a platform that enhances lateral flow tests, significantly improving their sensitivity and precision compared to traditional methods. AegirBio's product lineup includes the Veritope technology, which measures intact natalizumab for multiple sclerosis, alongside the MagniaReader, designed for both research and veterinary use. Their advancements enable robust, affordable, and easy-to-use testing instruments applicable across human health, veterinary, food safety, and environmental sectors. By leveraging novel techniques, AegirBio aims to expand the market for lateral flow tests and enhance patient care through more reliable diagnostics.

SpineX Inc. is a seed-stage medical device company focused on developing non-invasive neuromodulation devices aimed at addressing unmet medical needs in patients with neurological conditions. The company is engaged in clinical trials to evaluate the safety and effectiveness of its neuromodulation therapy specifically for individuals suffering from neurogenic bladder issues related to stroke, spinal cord injuries, or multiple sclerosis. SpineX's technologies are designed to enhance recovery and restore various functions, including bladder, bowel, respiration, sexual, and sensorimotor capabilities. One of its key products, the SCiP device, targets neurological dysfunction associated with conditions like cerebral palsy. By leveraging rigorously tested neuromodulation methods, SpineX aims to improve the quality of life for individuals affected by these debilitating conditions.

Subtle Medical, Inc. is a healthcare technology company based in Menlo Park, California, that specializes in developing AI-powered medical imaging software for clinical imaging centers and hospitals. Founded in 2017, the company offers products such as SubtleMR and SubtlePET, both of which are FDA cleared and CE marked. These technologies enhance image quality in magnetic resonance imaging (MRI) and positron emission tomography (PET) exams by reducing noise and increasing sharpness, ultimately improving workflow efficiency while ensuring patient safety. Subtle Medical also features SubtleGAD, a technology recognized by the Radiological Society of North America, which aims to make imaging exams safer. The company employs a vendor-agnostic AI infrastructure that integrates seamlessly with existing scanners, allowing imaging providers to serve more patients effectively by enhancing image acquisition without disrupting their current workflow. Through its innovations, Subtle Medical seeks to improve the quality, value, and accessibility of medical imaging while significantly lowering costs and radiation exposure.

Daxor Corporation is a medical device and biotechnology firm based in New York, specializing in blood volume measurement. The company developed the BVA-100 Blood Volume Analyzer, which is the first FDA-approved instrument designed to provide rapid and accurate measurement of a patient's true blood volume. This innovative device is utilized in diagnosing and treating various medical conditions, including congestive heart failure, hypertension, and anemia, among others. Daxor also offers additional services such as semen banking, blood storage, and laboratory testing. The company has established a cooperative research agreement with the Uniformed Services University of the Health Sciences to study the efficacy of the BVA-100 in assessing blood volume in traumatic injury contexts. Founded in 1970 and originally known as Idant Corporation, Daxor Corporation has positioned itself at the forefront of medical instrumentation technology.

NeuroGeneces utilizes advanced neuroscience, sleep expertise, and artificial intelligence to deliver brain health assessments aimed at enhancing cognitive longevity. The company has received funding from various reputable sources, including government agencies and private investors. Its flagship product is a sleep headband equipped with machine learning algorithms that analyze EEG data, comparing it against a proprietary normative database to determine an individual's biological brain age. This innovative approach allows healthcare practitioners to objectively evaluate brain function and develop targeted intervention strategies. Additionally, the device monitors sleep patterns, including quantity, quality, and heart rate variability, providing essential support for clinicians focused on wellness and preventative care. By identifying neurodegeneration early, NeuroGeneces aims to empower users to optimize their mental and physical performance.

Civatech Oncology is a medical device company based in Durham, North Carolina, that specializes in developing polymer-based devices for the treatment of cancer through localized low-dose-rate radiation. Founded in 2006, the company focuses on creating devices tailored for specific tumor types, utilizing its patented technology to manufacture them in various shapes and formats. Its flagship product, the CivaString, has received FDA 510k clearance for the treatment of any solid tumor. Civatech's innovative approach aims to enhance the efficacy of brachytherapy for early-stage cancers by reducing procedure times, ensuring uniform dose distribution, and minimizing patient trauma.

Diagmetrics develops innovative mask-based diagnostic systems designed to enhance testing accessibility for respiratory diseases, including Covid-19. The company's technology allows for the conversion of breath vapor into a fluid biosample, making it possible to retrofit existing masks for diagnostic purposes. This system provides users with the convenience of receiving test results directly on their smartphones via Bluetooth, enabling timely detection and monitoring of respiratory conditions. Diagmetrics aims to democratize health testing by integrating diagnostics into everyday items, thereby improving public health outcomes.

Novel Microdevices, LLC is focused on developing handheld devices for molecular diagnostics, specifically through its product, NOVEL DX. This innovative device utilizes microfluidics technology to analyze raw biological samples directly at the point of care, providing results in just 30 minutes. By enabling healthcare professionals to achieve lab-quality results without the need for a traditional laboratory setting, the device addresses various sectors including clinical diagnostics, biodefense, food safety, forensics, drug discovery, animal care, and agriculture. Founded in 2014 by Andrea Pais, Novel Microdevices is headquartered in Baltimore, Maryland.

EndoTheia is a medical equipment manufacturing company specializing in the development of advanced flexible endoscopic devices. The firm's technology incorporates micro-machined smart materials to produce highly dexterous manipulators that operate at millimeter and sub-millimeter scales. This innovation aims to enhance therapeutic outcomes for healthcare professionals conducting complex flexible endoscopic procedures. Through its focus on next-generation medical technology, EndoTheia seeks to improve the efficacy and precision of endoscopic interventions in various clinical settings.

University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

The University of Texas MD Anderson Cancer Center is a leading institution dedicated exclusively to cancer patient care, research, education, and prevention. Located in the Texas Medical Center in Houston, Texas, it was established as one of the original three comprehensive cancer centers under the National Cancer Act of 1971. MD Anderson serves as both a degree-granting academic institution and a specialized cancer treatment facility. It is affiliated with two prominent medical schools: The University of Texas Medical School at Houston and Baylor College of Medicine. Renowned for its exceptional cancer care, MD Anderson has consistently ranked among the top cancer hospitals in the United States, earning the No. 1 position in U.S. News & World Report's "Best Hospitals" survey for ten of the past twelve years. The center is widely recognized for its commitment to advancing cancer treatment and improving patient outcomes.

Sapphiros is a private equity growth and expansion firm founded in 2021 and based in Massachusetts. The company specializes in investing in growth-stage diagnostic companies, emphasizing innovative and patient-centric technologies. Its portfolio includes a diverse range of capabilities, such as advanced sample collection methods, next-generation diagnostics, computational biology, and printed electronics. By focusing on these areas, Sapphiros aims to enhance the global accessibility of essential diagnostic results for consumers, thereby contributing to advancements in healthcare and diagnostic-related innovations.

Sensor-Kinesis Corporation develops innovative medical devices focused on pathogen and virus detection. Founded in 2013 and based in Los Angeles, the company is advancing proprietary biosensor technology that integrates flexible micro biosensor chips with computer systems. These chips are designed to detect specific biomolecules and can be printed on various surfaces, enabling widespread application across multiple industries, including healthcare, food safety, and pharmaceuticals. By linking these sensors to smart devices, users can transmit and analyze biological signals in real time, facilitating improved health monitoring. Sensor-Kinesis aims to empower healthcare professionals and individuals with affordable, portable devices that provide enhanced detection capabilities for diseases and health-related risks, promoting better health outcomes and safety.

Vivani Medical is a preclinical-stage biopharmaceutical company focused on developing innovative medical solutions for chronic diseases and visual impairments. The company specializes in creating implantable visual prosthetics, including a retinal prosthesis designed to restore sight to individuals blinded by outer retinal degenerations such as Retinitis Pigmentosa. Utilizing its proprietary NanoPortal technology, Vivani Medical manufactures miniaturized, subdermal implants that facilitate long-term, consistent delivery of various medications. Through its commitment to research and development, Vivani Medical aims to enhance the quality of life for patients, enabling greater independence for those affected by vision loss and chronic conditions. Founded in 1998 and based in Sylmar, California, the company operates with two main divisions: Biopharm and Neuromodulation, focusing on innovative solutions in the medical field.

Prapela is a company that offers noninvasive stimulation therapy designed to enhance the health of newborns, specifically targeting issues such as irregular breathing and low oxygenation. By placing a reusable pad inside a hospital bassinet or incubator, Prapela provides gentle stimulation that supports the natural processes of breathing control and oxygenation. This therapy aims to improve cardiorespiratory outcomes while reducing the need for pharmacotherapy and minimizing the duration of conventional treatments for severe medical conditions. Since its inception, Prapela has garnered significant recognition as a leading pediatric medical device startup, receiving multiple awards and over $8 million in grants. The company collaborates with neonatologists, the National Institutes of Health, and the FDA to develop and refine its solutions, contributing to better health outcomes for newborns.

Actuated Medical, Inc. engages in outsourced research and development, designing and modeling, prototyping, and manufacturing medical devices. It offers occlusion clearing systems, such as NG-Clear for removing and disintegrating nasogastric (NG) tube clogs; and PEG-Clear for clearing and breaking up percutaneous endoscopic gastrostomy (PEG) tube clogs. The company also provides controlled tissue penetration systems, including resonance assisted insertion lancets for humane blood sampling of research subjects; low insertion force epidural systems for the entry of epidural needles; and resonance assisted vascular entry needles for aiding in vascular access for compromised and difficult access patients. In addition, Actuated Medical, Inc. offers magnetic resonance imaging compatible systems, such as direct drive motor for improving patient care by enabling various diagnostic and surgical procedures to be performed during MRI imaging; and transdermal patches for administering long-term and controlled-delivery medications subcutaneously. The company was formerly known as Piezo Resonance Innovations, Inc. and changed its name to Actuated Medical, Inc. in September 2011. Actuated Medical, Inc. was founded in 2006 and is based in Bellefonte, Pennsylvania.

PharmaJet, Inc. is a company that specializes in the development and marketing of needle-free injection devices for the vaccine delivery sector. Founded in 2005 and headquartered in Golden, Colorado, PharmaJet offers products under the Stratis and Tropis brands. These innovative devices utilize a narrow stream of fluid to deliver vaccines intramuscularly, subcutaneously, or intradermally without the use of needles. This technology aims to address significant issues associated with traditional needle-syringe methods, such as the risk of needle-stick injuries, potential needle reuse, cross-contamination, and the disposal of sharps waste. By providing a user-friendly and cost-effective alternative for fluid injection, PharmaJet's products enhance safety and comfort for both healthcare providers and patients, while also contributing to a positive return on investment in the immunization market.

Linshom is focused on providing continuous respiratory monitoring solutions that include measurements of Tidal Volume at the patient's bedside or in home settings. The company has developed a wearable sensor that is FDA cleared, designed to enable continuous, predictive respiratory monitoring. This technology allows for early detection of respiratory decline, which can help prevent costly rapid response situations, ICU transfers, and potential fatalities. By addressing a critical unmet medical need, Linshom aims to enhance patient care and improve outcomes through advanced respiratory monitoring capabilities.

BIOS Health is a pioneering company focused on developing neural digital therapies by leveraging data from the human nervous system. By identifying neural biomarkers that correlate nerve activity to specific medical conditions, BIOS aims to revolutionize precision medicine. Their research offers the potential for innovative treatments for a range of chronic diseases, including hypertension, diabetes, and neurodegenerative disorders such as Parkinson's and Alzheimer's. Co-founded by experts from Cambridge University, the team includes professionals from diverse fields such as neuroscience, machine learning, and biotechnology. Additionally, BIOS is working on prosthetic connectors that standardize connections between bionic devices and neural systems, facilitating neural control and feedback for amputees. This dual approach positions BIOS at the forefront of improving the quality of life for individuals with chronic conditions and those requiring prosthetic solutions.

University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Neurovations, a patient care and innovation company, was founded in 1992 by CEO Dr. Eric Grigsby. Today, Neurovations is a national leader in medical device and pharmaceutical innovation, clinical research, and a world-class education program focusing in pain and neuroscience. Dr. Grigsby is deeply connected to the healthcare community through our non-profit HealthRoots Foundation. Our unwavering mission is to inspire hope and to contribute to the health and well-being of our patients and communities through integrated clinical practice, research, and education.

Rescue Biomedical Services is a medical equipment repair company serving Southern California.

Efemoral Medical is a medical technology company focused on creating durable, minimally invasive treatment solutions for patients with peripheral vascular disease. The company's flagship product, the Efemoral Vascular Scaffold System (EVSS) featuring FlexStep Technology, aims to improve treatment strategies for peripheral artery disease (PAD) interventions. This innovative technology includes a bioresorbable intravascular stent designed to maintain or enhance the patency of blood vessels, specifically in peripheral locations, thereby enabling healthcare providers to deliver effective treatments for patients suffering from this condition.

Eko Health is a leading digital health company advancing how healthcare professionals detect and monitor heart and lung disease with its portfolio of digital stethoscopes, patient and provider software, and AI-powered analysis. Its FDA-cleared platform is used by hundreds of thousands of healthcare professionals worldwide, allowing them to detect earlier and with higher accuracy, diagnose with more confidence, manage treatment effectively, and ultimately give their patients the best care possible. Eko Health is headquartered in Emeryville, California, with over $125 million in funding from Highland Capital Partners, Questa Capital, Artis Ventures, DigiTx Partners, NTTVC, Morningside Technology Ventures Limited, Mayo Clinic, Sutter Health, and others. For more information visit www.ekohealth.com.

Evaxion Biotech A/S is a clinical-stage biotechnology company focused on utilizing artificial intelligence to decode the human immune system and develop innovative immunotherapies for cancer and infectious diseases. The company leverages its proprietary AI-immunology technology to create a diverse pipeline of product candidates, which includes three patient-specific cancer immunotherapies—two of which are in Phase I/IIa clinical trials. In addition to its cancer treatments, Evaxion is also advancing a portfolio of vaccines aimed at preventing bacterial and viral infections, with one program targeting Methicillin-resistant Staphylococcus aureus currently in preclinical development. By combining AI with immunology, Evaxion seeks to improve therapeutic efficacy for patients with unmet medical needs.

Matregenix is a MedTech company based in Irvine, California, founded in 2018 by Sherif Soliman. The company specializes in the development and manufacturing of advanced nanofibrous materials tailored for various medical applications. Its flagship product, MatriNova, is a barrier membrane designed for periodontal surgeries, featuring customizable characteristics that enhance its performance. Utilizing electrospinning technology, Matregenix produces materials with predictable resorption times and improved handling properties. In addition to its focus on the biomedical sector, the company also offers comprehensive contract development and manufacturing services aimed at assisting manufacturers in bringing innovative products to market.

Sequitur Health, founded in 2019 and based in Scottsdale, Arizona, specializes in the development of innovative medical devices aimed at enhancing patient care and improving quality of life. The company focuses on addressing unmet needs of patients and physicians by leveraging technological advancements. By collaborating with educational and medical institutions in Arizona, Sequitur Health creates solutions that enable healthcare providers to deliver timely and effective care to patients.

Virtuoso Surgical focuses on developing robotic tools specifically for minimally invasive endoscopic surgery. The company's surgical system features needle-sized robotic arms that allow surgeons to navigate and operate in hard-to-reach areas of the body, addressing limitations posed by traditional endoscopes. By providing dexterous and accurate instruments, Virtuoso Surgical aims to enhance surgical precision and improve patient outcomes while also offering a cost-effective solution for healthcare providers.

PETcoil, founded in 2018, is a company focused on enhancing healthcare through innovative medical imaging technology. Originating from research at Stanford University, the company has developed a groundbreaking radiofrequency-penetrable PET insert system that allows for simultaneous PET and MRI imaging. This patented portable PET scanner can be integrated into existing MRI machines, providing clinicians with the ability to obtain more precise and detailed images of patients' bodies. PETcoil's mission is to create affordable, high-performance molecular imaging systems that facilitate early and accurate disease diagnosis, making multi-modality medical imaging accessible to all patients in need.

Vivani Medical is a preclinical-stage biopharmaceutical company focused on developing innovative medical solutions for chronic diseases and visual impairments. The company specializes in creating implantable visual prosthetics, including a retinal prosthesis designed to restore sight to individuals blinded by outer retinal degenerations such as Retinitis Pigmentosa. Utilizing its proprietary NanoPortal technology, Vivani Medical manufactures miniaturized, subdermal implants that facilitate long-term, consistent delivery of various medications. Through its commitment to research and development, Vivani Medical aims to enhance the quality of life for patients, enabling greater independence for those affected by vision loss and chronic conditions. Founded in 1998 and based in Sylmar, California, the company operates with two main divisions: Biopharm and Neuromodulation, focusing on innovative solutions in the medical field.

Eliaz Therapeutics has developed a patented medical device that selectively removes galectin-3 from human blood, addressing currently untreatable life-threatening diseases. This device targets galectin-3, a protein associated with conditions such as diabetes, chronic kidney disease, organ fibrosis, and cancer. By employing a single-use apheresis column that utilizes a proprietary capturing molecule, the device effectively eliminates both bound and free galectin-3 from circulation. This innovative approach offers a less invasive treatment option with fewer side effects compared to traditional therapies, enabling physicians to provide effective care for patients suffering from acute kidney injury, sepsis, and other inflammatory and fibrotic diseases. The device is designed for easy integration into existing hospital practices, enhancing its potential for widespread adoption.

Ramona develops advanced microscopy tools designed to enhance cellular-level research by capturing detailed images over vast areas. The company's innovative microscope employs custom control electronics to efficiently process large volumes of image data from multiple micro-cameras, allowing researchers to capture and analyze extensive gigapixel datasets. This capability not only provides a wider field of view but also enables synchronous data capture, allowing for real-time observation of cellular processes. By offering a new perspective on cellular dynamics, Ramona's technology empowers researchers to make more informed decisions quickly and effectively.

Bright Uro is an early-stage medical technology company focused on developing innovative diagnostic devices for urology. The company has created a glean urodynamics system that combines advanced hardware, software, and data science to deliver wireless, catheter-free urodynamics. This system aims to enhance the accuracy and comfort of urological assessments, ultimately transforming the standard of care for patients with lower urinary tract symptoms and diseases. By providing actionable insights, Bright Uro empowers clinicians to improve patient outcomes and streamline the treatment process.

Sonavex, Inc. is a Baltimore-based company founded in 2013 that specializes in advanced imaging technology aimed at enhancing surgical outcomes. The company has developed a proprietary ultrasound-based platform that enables clinicians to detect anastomotic blood clots and assess critical intravascular flow metrics directly at the point of care. This technology not only facilitates the measurement of blood flow and vessel morphology but also includes bioresorbable and echogenic equipment to mark at-risk blood vessels for future assessments. By providing actionable data, Sonavex supports healthcare providers in monitoring and improving patient care, particularly in the context of post-operative complications.

University of Arkansas for Medical Sciences is an academic health center focusing on medical education, research, and clinical programs. It offers various medical services, including specialized care in areas such as women's health, cancer treatment, orthopedics, stroke care, and trauma.

Enspectra Health, based in Mountain View, California, specializes in developing advanced imaging systems for medical applications. The company has created the first hand-held multiphoton imager for human use, enabling real-time imaging of live cellular anatomy beneath the skin. Its innovative device combines reflectance confocal and multiphoton laser scanning microscopy to produce multispectral images that reveal details not visible to the naked eye. This technology aids researchers and dermatologists in examining the structure and function of various tissues, including muscle, tendon, cartilage, and skin, thereby enhancing the diagnosis and treatment of skin conditions, particularly skin cancers. Enspectra Health aims to simplify the evaluation process for physicians and improve patient outcomes through its cutting-edge imaging solutions.

Epicore Biosystems, Inc. is a Cambridge, Massachusetts-based company founded in 2017 that specializes in developing and commercializing a wearable microfluidic sensing platform. This innovative technology analyzes small droplets of sweat directly from the skin to provide insights into health, hydration, and athletic performance. The platform is designed to measure various biomarkers, including proteomics and inflammatory markers, allowing for personalized management of health and nutrition. Epicore's approach leverages over two decades of research in microfluidics and soft materials conducted by leading experts at Northwestern University. By offering a non-invasive and cost-effective solution, Epicore aims to enhance athletic performance and improve overall health monitoring for users.

Meridian Bioscience is an integrated life science company that develops, manufactures, and distributes clinical diagnostic test kits for gastrointestinal, viral, respiratory, and parasitic infectious diseases. The company specializes in molecular and immunological reagents, providing tools that support the discovery and diagnosis of various medical conditions. In addition to diagnostic test kits, Meridian offers bulk antigens, antibodies, PCR and qPCR reagents, nucleotides, and bioresearch reagents, serving researchers and other diagnostic manufacturers. Moreover, the company engages in contract development and manufacturing of proteins and other biologicals under cGMP conditions, catering to biopharmaceutical and biotechnology firms involved in drug and vaccine research. Meridian operates through three segments: U.S. Diagnostics, European Diagnostics, and Life Science, emphasizing its commitment to enhancing healthcare outcomes through innovative solutions.

Subtle Medical, Inc. is a healthcare technology company based in Menlo Park, California, that specializes in developing AI-powered medical imaging software for clinical imaging centers and hospitals. Founded in 2017, the company offers products such as SubtleMR and SubtlePET, both of which are FDA cleared and CE marked. These technologies enhance image quality in magnetic resonance imaging (MRI) and positron emission tomography (PET) exams by reducing noise and increasing sharpness, ultimately improving workflow efficiency while ensuring patient safety. Subtle Medical also features SubtleGAD, a technology recognized by the Radiological Society of North America, which aims to make imaging exams safer. The company employs a vendor-agnostic AI infrastructure that integrates seamlessly with existing scanners, allowing imaging providers to serve more patients effectively by enhancing image acquisition without disrupting their current workflow. Through its innovations, Subtle Medical seeks to improve the quality, value, and accessibility of medical imaging while significantly lowering costs and radiation exposure.

Phase provides 3D-printing medical devices for microfluidics. Phase’s proprietary platform enables PDMS (Sylgard 184) to be 3D printed at a scale and resolution that was previously unattainable.

Bleep provides best new CPAP solution on the market. Not sleeping sucks. Not sleeping and spending a fortune on CPAP devices that leak, fall off or leave marks on your face sucks even worse. That’s why they invented the DreamPort Sleep Solution – the world’s first-ever mask less CPAP device. The result is the smallest, lightest, most ergonomically accommodating CPAP solution on the market – a device that fits comfortably and doesn’t restrict your movement – enabling patients to get a better night’s sleep. Their goal is simple – to make the best bleeping CPAP products on the planet. They won’t stop until every sleep apnea patient is sleeping like a baby.

Medentum Innovations promotes health equity and transforming healthcare through affordable, high-performance point-of-care devices and AI diagnostics.

Delpor, Inc. is engaged in the development of innovative drug delivery technologies that facilitate the sustained or pattern-specific release of proteins, peptides, and small molecules via a small non-mechanical subcutaneous implant. The company offers several technologies, including Prozor, which delivers antipsychotics and other small molecule drugs, and NANOPOR, designed for sustained release through specialized membrane architecture. Additionally, Delpor has developed the Delos PUMP, a self-contained device that allows for the pulsed delivery of medications at programmed intervals, benefiting treatments such as hormones for fertility, diabetes management, and pain relief. Founded in 2009 and located in San Francisco, California, Delpor aims to enhance medication adherence and patient convenience by providing an alternative to frequent injections through its implantable solutions.

Lightengale is a developer of medical devices focused on enhancing safety in healthcare settings, particularly in intensive care units. The company has created an innovative infusion line that utilizes light-emitting cables to illuminate individual intravenous (IV) lines from the pump to the patient. This design addresses the critical issue of line mix-ups and medication delivery errors, which can pose significant risks to patient safety. By providing visual cues for nurses to accurately trace IV lines, Lightengale's technology allows healthcare professionals to dedicate more time to patient care, ultimately improving the overall quality of medical treatment.

Annoviant is a healthcare company focused on the development of innovative medical devices, specifically tissue-based valve and conduit replacement products. These devices are designed to replace or repair structures that are congenitally absent or underdeveloped. Annoviant's offerings are characterized by their regenerative capabilities and resistance to thrombosis, calcification, and infection. By maintaining essential mechanical properties, these devices aim to enhance clinical outcomes for substitute conduit arteries in infants and children, ultimately reducing the need for repeated surgical interventions.

Autonomous Healthcare is a medical technology company focused on transforming clinical care workflows through automation. By developing advanced healthcare technologies, it aims to revolutionize critical care and peri-operative care. The company's solutions continuously analyze bedside monitoring data to identify and address adverse events, thereby enhancing patient safety and care efficiency. This innovative approach enables healthcare professionals to reduce hospital lengths of stay for patients, ultimately improving overall healthcare outcomes.

ThermoGenesis Holdings develops and markets automated technologies for chimeric antigen receptor (CAR)-T and other cell-based therapies. The company offers a range of solutions for clinical biobanking, point-of-care applications, and automation in immuno-oncology. Key products include the AXP Automated Cell Separation System for isolating stem cells from umbilical cord blood, the BioArchive Automated Cryopreservation System for cryogenic storage, the PXP Point-of-Care System for processing autologous stem cells at surgical centers or clinics, and the CAR-TXpress platform for streamlining CAR-T immunotherapy manufacturing. Additionally, ThermoGenesis provides X-Series products for various cell purification tasks and the AR-TXpress Platform for large-scale cellular processing. Founded in 1986 and headquartered in Rancho Cordova, California, the company was formerly known as Cesca Therapeutics Inc.

Vibrato Medical is focused on developing a noninvasive therapeutic ultrasound device aimed at treating Critical Limb Ischemia and Peripheral Arterial Disease. This innovative technology is designed to enhance tissue perfusion, alleviate symptoms, and prevent limb loss by promoting vasodilation and vessel growth. Drawing on extensive research and the latest advancements in ultrasound technology, Vibrato Medical's device is the first of its kind that can be worn and used conveniently at home without the need for surgical incisions. This approach offers patients an accessible and effective option for managing their conditions.

On average, we spend a third of our lives in bed. Our self-positioning bed; the Korus™, combined with our AI-driven software, is designed to provide precise sleep therapies improving lifestyle and medical care that benefits sleep wellness and faster recovery at home.

Amydis is a privately-held pharmaceutical company focused on developing innovative diagnostic solutions for diseases associated with amyloid proteins. The company aims to create a universal, non-invasive diagnostic tool that is faster, more accessible, and affordable than existing tests for conditions with unmet clinical needs. Amydis has developed a platform of novel compounds that fluoresce upon binding to amyloid proteins, facilitating the diagnosis of various diseases. Its primary focus is on the early detection of Alzheimer's disease, but it also explores potential applications for detecting Parkinson’s disease, Creutzfeldt-Jakob disease, Pre-eclampsia, TTR Amyloidosis, and Cerebral Amyloid Angiopathy. By providing diagnostic capabilities for amyloid-associated diseases, Amydis empowers patients and healthcare professionals to make informed decisions about health risks.

Eclipse Regenesis is a development-stage medical device company dedicated to leveraging the body's natural tissue regeneration mechanisms to treat significant health conditions. The company is focused on its flagship product, the Eclipse XL1 System™, which employs distraction enterogenesis to mechanically stimulate the production of new, fully functional intestinal tissue. This innovative approach aims to address Short Bowel Syndrome (SBS), a condition that currently has no cure and leads to severe nutritional malabsorption due to insufficient functional small intestine. Supported by over 15 years of scientific research and collaboration with SBS experts globally, Eclipse Regenesis is committed to advancing restorative therapies for patients suffering from this challenging disorder. The Eclipse XL1 System is still investigational and not yet available for commercial use.

Hesperos, Inc. specializes in the development of Human-on-a-Chip microfluidic systems aimed at transforming toxicology testing and drug discovery efficacy evaluations. Founded by Michael L. Shuler and James J. Hickman, the company focuses on creating pumpless platforms that utilize serum-free cellular mediums to facilitate communication between multi-organ systems. Their innovative technology incorporates integrated computational pharmacokinetics and pharmacodynamics modeling, allowing for live physiological response assessments through functional readouts from various tissues, including neurons, cardiac, muscle, and barrier tissues, as well as the liver and pancreas. This approach enables clients to predict in vivo functions without relying on animal models, advancing the field of biomedical research.

NeuroPace, Inc. is a medical device company based in Mountain View, California, that specializes in developing and manufacturing implantable devices for treating neurological disorders, particularly epilepsy. The company's primary product is the Responsive Neurostimulator (RNS) System, designed for patients with medically refractory partial epilepsy. This system includes a small implantable neurostimulator that monitors brain activity and delivers targeted electrical pulses to specific seizure onset areas. The RNS System comprises both implantable components, such as depth leads and cortical strip leads, and external products, including a programmer that facilitates communication with the implanted device. Founded in 1997, NeuroPace aims to transform the lives of individuals suffering from epilepsy by significantly reducing or eliminating seizures through its innovative technology. The company primarily generates revenue from sales of the RNS System to hospitals and medical facilities that perform the implantation procedures.

Ramona develops advanced microscopy tools designed to enhance cellular-level research by capturing detailed images over vast areas. The company's innovative microscope employs custom control electronics to efficiently process large volumes of image data from multiple micro-cameras, allowing researchers to capture and analyze extensive gigapixel datasets. This capability not only provides a wider field of view but also enables synchronous data capture, allowing for real-time observation of cellular processes. By offering a new perspective on cellular dynamics, Ramona's technology empowers researchers to make more informed decisions quickly and effectively.

Enspectra Health, based in Mountain View, California, specializes in developing advanced imaging systems for medical applications. The company has created the first hand-held multiphoton imager for human use, enabling real-time imaging of live cellular anatomy beneath the skin. Its innovative device combines reflectance confocal and multiphoton laser scanning microscopy to produce multispectral images that reveal details not visible to the naked eye. This technology aids researchers and dermatologists in examining the structure and function of various tissues, including muscle, tendon, cartilage, and skin, thereby enhancing the diagnosis and treatment of skin conditions, particularly skin cancers. Enspectra Health aims to simplify the evaluation process for physicians and improve patient outcomes through its cutting-edge imaging solutions.

Prapela is a company that offers noninvasive stimulation therapy designed to enhance the health of newborns, specifically targeting issues such as irregular breathing and low oxygenation. By placing a reusable pad inside a hospital bassinet or incubator, Prapela provides gentle stimulation that supports the natural processes of breathing control and oxygenation. This therapy aims to improve cardiorespiratory outcomes while reducing the need for pharmacotherapy and minimizing the duration of conventional treatments for severe medical conditions. Since its inception, Prapela has garnered significant recognition as a leading pediatric medical device startup, receiving multiple awards and over $8 million in grants. The company collaborates with neonatologists, the National Institutes of Health, and the FDA to develop and refine its solutions, contributing to better health outcomes for newborns.

BiVACOR, Inc., founded in 2008 and based in Houston, Texas, specializes in the design and manufacture of centrifugal heart pumps aimed at replacing the functions of failing hearts. The company has developed an innovative artificial heart-pumping device that features a compact design with a magnetically levitated rotor situated between opposing pump casings. This advanced rotary blood pump technology is engineered to deliver the necessary cardiac output while minimizing the risks of blood-cell damage and clotting. BiVACOR's team comprises skilled engineers, medical specialists, and business executives who collaborate to enhance this groundbreaking technology. The company also maintains an international office in Brisbane, Australia, fostering a strong network to support its mission.

BioCircuit Technologies, Inc. is a medical device company based in Atlanta, Georgia, founded in 2016. The company specializes in the development of noninvasive electrophysiology devices aimed at monitoring, controlling, and repairing peripheral nerves. By utilizing multi-electrode arrays and proprietary algorithms, BioCircuit's products enable clinicians to diagnose health conditions at an earlier stage, track the progression of symptoms over time, and select more precise treatments tailored to individual patients' needs. This innovative approach enhances the ability of healthcare providers to address nerve-related issues effectively.

Xtrava Health, established in 2014 and headquartered in Santa Clara, California, specializes in developing contactless bio-sensing technology for health and wellness applications. The company's flagship product, Butterfly, is a wearable child wellness monitor that automatically tracks vital signs, sleep patterns, feeding, diaper changes, and activities, providing parents with comprehensive insights. Xtrava Health also develops and commercializes simple, accurate, and affordable diagnostic products for both professional and at-home use, focusing on respiratory health and employee wellness monitoring.

MRIMath specializes in medical imaging technology aimed at improving cancer diagnosis and treatment. The company develops solutions that assist oncologists and surgeons in identifying tumors and assessing treatment responses, thereby enhancing patient outcomes in oncology. MRIMath's innovative approach incorporates an interactive human-AI interface that offers a reliable and cost-effective tool for medical practitioners to monitor brain tumor growth. Beyond its imaging technology, MRIMath also provides hospital care, medical device services, and AI consulting, along with AI-powered software designed to streamline healthcare processes.

Neurotype is a medical device company dedicated to addressing the challenges of addiction, particularly the environmental triggers that can lead to drug cravings and relapse. Its flagship product, the NeuromarkR platform, consists of a headset and accompanying software that objectively measures brain signatures associated with drug cravings. This innovative technology aims to enhance treatment for individuals recovering from addiction by identifying specific triggers linked to their past drug use. Neurotype's approach incorporates tailored psychotherapy strategies, including Cognitive Behavioral Therapy and Mindfulness-Based Treatment, to provide targeted interventions that help patients manage their cravings more effectively. By focusing on the underlying brain circuits involved in addiction, Neurotype seeks to improve mental and behavioral healthcare for those affected by substance use disorders.

Abterra Biosciences specializes in antibody discovery and sequencing services aimed at enhancing therapeutic antibody development. The company utilizes advanced technologies, including next-generation sequencing, mass spectrometry, and machine learning, to analyze antibody responses and rapidly identify high-affinity therapeutic antibodies. Its innovative platform, Alicanto, streamlines the discovery process by identifying target-specific antibodies directly from serum, eliminating the need for traditional and time-consuming methods such as cell selection and cloning. By combining the expertise of data scientists and biologists, Abterra Biosciences aims to provide healthcare researchers with new insights and efficient solutions in the field of antibody therapeutics.

Meridian Bioscience is an integrated life science company that develops, manufactures, and distributes clinical diagnostic test kits for gastrointestinal, viral, respiratory, and parasitic infectious diseases. The company specializes in molecular and immunological reagents, providing tools that support the discovery and diagnosis of various medical conditions. In addition to diagnostic test kits, Meridian offers bulk antigens, antibodies, PCR and qPCR reagents, nucleotides, and bioresearch reagents, serving researchers and other diagnostic manufacturers. Moreover, the company engages in contract development and manufacturing of proteins and other biologicals under cGMP conditions, catering to biopharmaceutical and biotechnology firms involved in drug and vaccine research. Meridian operates through three segments: U.S. Diagnostics, European Diagnostics, and Life Science, emphasizing its commitment to enhancing healthcare outcomes through innovative solutions.

Abterra Biosciences specializes in antibody discovery and sequencing services aimed at enhancing therapeutic antibody development. The company utilizes advanced technologies, including next-generation sequencing, mass spectrometry, and machine learning, to analyze antibody responses and rapidly identify high-affinity therapeutic antibodies. Its innovative platform, Alicanto, streamlines the discovery process by identifying target-specific antibodies directly from serum, eliminating the need for traditional and time-consuming methods such as cell selection and cloning. By combining the expertise of data scientists and biologists, Abterra Biosciences aims to provide healthcare researchers with new insights and efficient solutions in the field of antibody therapeutics.

Versiti provides innovative, value-added solutions in the fields of transfusion medicine, transplantation, and blood-related diseases.

CardiaLen, Inc. is a medical device company based in Minneapolis, Minnesota, specializing in the development of innovative therapies for atrial fibrillation and other heart arrhythmias. Founded in 2008, the company is focused on creating implantable, low-energy cardioverter devices that offer pain-free cardioversion therapies. These devices monitor the heartbeat and employ a proprietary series of low-energy pulses to restore normal heart rhythm while minimizing discomfort and preventing damage to heart tissue. By addressing significant unmet needs in the treatment of atrial fibrillation, CardiaLen aims to enhance patient outcomes and reduce reliance on high-energy defibrillation shocks.

Meridian Bioscience is an integrated life science company that develops, manufactures, and distributes clinical diagnostic test kits for gastrointestinal, viral, respiratory, and parasitic infectious diseases. The company specializes in molecular and immunological reagents, providing tools that support the discovery and diagnosis of various medical conditions. In addition to diagnostic test kits, Meridian offers bulk antigens, antibodies, PCR and qPCR reagents, nucleotides, and bioresearch reagents, serving researchers and other diagnostic manufacturers. Moreover, the company engages in contract development and manufacturing of proteins and other biologicals under cGMP conditions, catering to biopharmaceutical and biotechnology firms involved in drug and vaccine research. Meridian operates through three segments: U.S. Diagnostics, European Diagnostics, and Life Science, emphasizing its commitment to enhancing healthcare outcomes through innovative solutions.

Biomotum specializes in the design and manufacturing of wearable robotic exoskeletons aimed at improving mobility for individuals facing challenges in walking. The company addresses the growing health issues related to mobility impairments, particularly for those affected by neurological disorders such as stroke and cerebral palsy. Biomotum's innovative systems integrate advanced assistive technology, offering a user-friendly therapeutic solution that features real-time training insights, compatibility with tele-rehabilitation, and built-in progress reporting. This approach enhances the rehabilitation process for users, empowering them to regain mobility and improve their quality of life.

EYSZ is a digital health software company based in Piedmont, California, founded in 2018. It specializes in detection algorithms that utilize oculometric and facial biometric data to reliably detect seizures and assist in the diagnosis and management of brain disorders, including epilepsy, ADHD, and depression. By employing machine learning techniques, EYSZ's software not only detects seizures but also predicts their occurrence. The platform is designed to interface and integrate with various eye-tracking systems, such as smart glasses, and therapeutic devices like neuromodulation tools, thereby enhancing the ability of clinicians to monitor and manage the neurological health of their patients effectively.