The National Science Foundation (NSF) is an independent federal agency established in 1950 and based in Alexandria, Virginia. It is dedicated to supporting research and education in science and engineering across a wide range of disciplines. The NSF provides significant non-dilutive funding, up to $1.5 million, to startups and small businesses through its America's Seed Fund initiative, which is part of the Small Business Innovation Research (SBIR) program mandated by Congress. With an operating budget of approximately $7.8 billion, the NSF is committed to advancing fundamental research and education, thus fostering innovation and technological development in the United States.
The San Diego Supercomputer Center (SDSC) enables international science and engineering discoveries through advances in computational science and data-intensive, high-performance computing. It provides access to a vast array of data and computational resources and services for all UC researchers who need cyberinfrastructure beyond their own laboratories, classrooms, departments, and academic units. SDSC’s research cyberinfrastructure includes: data-intensive computing resources to the academic and industrial communities through the RCI program's Triton Shared Computing Cluster (TSCC), a high-impact data analysis and preservation system featuring a large-scale disk storage facility, a data analysis facility for petascale research, and a shared research cluster; Gordon, the first high-performance supercomputer to use massive amounts of flash-based memory to speed solutions for data-intensive problems; Trestles, which also features flash-based memory, with a design tailored to the majority of user jobs rather than a handful of researchers who run jobs at thousands of core counts; a green data center equipped to house co-location servers; and an environment for all things related to data, including management, mining, curation, analysis, visualization, access and preservation as well as data storage technologies. Along with its broad spectrum of software, hardware, networking, and information resources, SDSC also offers users full-time support including 24-hour helpdesk services, code optimization, training, portal development, and a variety of other services. San Diego Supercomputer Center was founded in 1985.
Rubi Laboratories
Grant in 2024
Rubi Laboratories is a California-based company that specializes in the development of technology to manufacture carbon-negative textiles. The firm utilizes innovative sustainable solutions to convert carbon emissions into natural fibers, resulting in biodegradable textiles. Its technology directly synthesizes threads, providing a natural resource for the production of viscose that is carbon-negative, as well as being water-chemical, land-neutral, traceable, and environmentally friendly. Rubi Laboratories aims to address the environmental impact of textile manufacturing by offering a more sustainable alternative in the industry.
University of California Irvine
Grant in 2024
University of California, Irvine is a higher education institution providing diverse academic and cultural events. It also offers a variety of events such as art exhibitions, music performances, healthcare conferences, theatrical productions, and educational seminars to the general public and its student body.
University of California San Diego
Grant in 2024
The University of California San Diego (UC San Diego) is a public research university renowned for its diverse undergraduate and graduate programs across multiple disciplines. It emphasizes research, community engagement, and interdisciplinary collaboration, making it a hub for innovation and education. The university houses the School of Medicine, which prepares students for careers in healthcare by equipping them with the necessary knowledge and skills to become dedicated medical professionals. Additionally, UC San Diego fosters a multidisciplinary approach to complex systems through its human-centered design thinking labs, collaborating with various industrial partners in fields such as automation and healthcare. It actively supports student involvement in leadership and offers resources for studying abroad, enhancing the overall educational experience.
Agrology
Grant in 2023
Agrology is an agricultural technology company recognized for its contributions to sustainable farming practices and a recipient of a National Science Foundation award. Operating from offices in Alexandria, Virginia, and Salinas, California, Agrology provides real-time data that enables growers to assess the ecological and agronomic impacts of regenerative farming. The company focuses on monitoring soil health, microbial activity, carbon cycles, nitrous oxide emissions, net ecosystem exchange, and microclimatic conditions. This data helps farmers connect regenerative practices to measurable reductions in greenhouse gases and other ecological benefits. Additionally, Agrology's predictive agriculture system offers insights that assist farmers in adapting to climate change while improving soil sequestration and generating carbon credits. The company is trusted by prominent growers, researchers, and global consumer packaged goods brands.
EYSZ
Grant in 2023
EYSZ is a digital health software company based in Piedmont, California, founded in 2018. It specializes in detection algorithms that utilize oculometric and facial biometric data to reliably detect seizures and assist in the diagnosis and management of brain disorders, including epilepsy, ADHD, and depression. By employing machine learning techniques, EYSZ's software not only detects seizures but also predicts their occurrence. The platform is designed to interface and integrate with various eye-tracking systems, such as smart glasses, and therapeutic devices like neuromodulation tools, thereby enhancing the ability of clinicians to monitor and manage the neurological health of their patients effectively.
Nexilico
Grant in 2023
Nexilico, Inc. is an early-stage biotechnology company based in Albany, California, specializing in precision medicine and microbiome research and development. Founded in 2017, the company focuses on creating advanced predictive computational platforms to enhance drug design and development processes. By pioneering next-generation in silico microbiome technologies, Nexilico aims to deepen the scientific understanding of microbiomes and their impact on health and disease. This knowledge is leveraged to create innovative microbiome-based solutions that improve therapeutic outcomes for various medical treatments.
California State University, Los Angeles Endowment
Grant in 2022
California State University, Los Angeles (Cal State LA) is a leading public university located in Los Angeles, recognized for its commitment to student upward mobility. Established in 1947, the university serves over 28,000 students and boasts a network of more than 245,000 alumni. Cal State LA offers a range of nationally recognized programs across various fields, including science, the arts, business, criminal justice, engineering, nursing, education, and the humanities. The university is also notable for its facilities, which include the Luckman Fine Arts Complex, Pat Brown Institute for Public Affairs, and the Hydrogen Research and Fueling Facility. Furthermore, Cal State LA manages an endowment fund that supports scholarships, research, and academic programs, ensuring its mission of engagement and service to the community is upheld.
Sylvatex
Grant in 2022
Sylvatex, Inc. is a fuel technology company based in Los Angeles, California, founded in 2007. It specializes in the development of a unique process that combines vegetable-oil-based surfactants with microbubbles of water and ethanol to create a microemulsion. This innovative approach enables oil companies to lower their production costs while facilitating the generation of green diesel fuel. Sylvatex's technology aims to enhance the efficiency and sustainability of fuel production, contributing to a transition towards more environmentally friendly energy sources.
Xona Space Systems
Grant in 2022
Xona Space Systems, Inc. specializes in developing and manufacturing position, navigation, and timing (PNT) satellite solutions. Founded in 2019 and headquartered in San Mateo, California, the company is focused on creating a constellation of low-cost, low-Earth orbiting satellites designed to enhance navigation for various applications, including autonomous vehicles, unmanned aerial vehicles, and mobile robotics. Their flagship product, the Xona Pulsar, delivers high-power signals from low Earth orbit, ensuring secure and accurate navigation and timing services. This innovative approach aims to meet the demands of smart transportation and smart infrastructure, providing the resilience and precision necessary for modern intelligent systems to operate safely and efficiently at scale.
Protabit
Grant in 2022
Protabit specializes in protein engineering for various sectors, including industrial, agricultural, and healthcare applications. The company employs a unique platform technology that integrates computational modeling with high-throughput screening and directed evolution to enhance the diversity of protein sequences. This innovative approach allows Protabit to produce novel proteins tailored to specific needs. The development of their technology is supported by strategic partnerships with notable organizations, including Monsanto Company and the California Institute of Technology. Through its advanced methodologies, Protabit aims to advance the field of protein design and provide customized solutions for its clients.
Skuchain
Grant in 2022
Skuchain, Inc. is a company that specializes in developing blockchain-based products aimed at enhancing B2B trade and supply chain finance. Founded in 2014 and based in Mountain View, California, Skuchain offers a platform that includes features for procurement, contract management, financing arrangements, and inventory tracking. One of its notable products is BRACKETS, a smart lock system that automates monetary transactions when contractual agreements are fulfilled. The company’s currency-agnostic approach ensures that businesses can achieve greater transparency, security, and efficiency throughout their supply chains, catering primarily to banks and manufacturers.
Evolution Devices
Grant in 2022
Evolution Devices, Inc. is a neuro rehabilitation technology company based in Berkeley, California, focused on enhancing mobility for individuals with neurological impairments. The company’s flagship product, EvoWalk, is a bio-electronic wearable device that utilizes functional electrical stimulation and artificial intelligence to track walking patterns and personalize rehabilitation therapy. EvoWalk is designed for patients recovering from conditions such as stroke, multiple sclerosis, ALS, cerebral palsy, traumatic brain injury, and incomplete spinal cord injury. The device employs sensors that deliver electrical stimulation to leg muscles and the peroneal nerve, aiding in foot elevation during walking. This technology aims to eliminate foot drop, reduce fatigue, and minimize the risk of tripping accidents. Evolution Devices, formerly known as Foot++, Inc., was established in 2017 and rebranded in September 2019.
CoLabs
Grant in 2022
CoLabs Inc. is a medical device manufacturing company based in Morgan Hill, California, established in 2012. The company specializes in developing Ventor, an emergency airway and ventilation system designed to enhance airway management and ventilation during cardiac arrest situations. This innovative device aims to provide medical professionals with a new approach to effectively manage patients experiencing cardiac arrest, facilitating better diagnosis and treatment during critical emergencies.
Oculogenex
Grant in 2022
Oculogenex is a biopharmaceutical company based in La Habra, California, established in 2020. The company specializes in developing gene therapies specifically aimed at treating retinal disorders. Its innovative approach involves ocular regenerative gene therapy that protects retinal pigment epithelial cells from oxidative stress-induced damage, which is a contributing factor to macular degeneration. By focusing on these therapies, Oculogenex aims to enhance the detection and treatment of various retinal disorders, ultimately supporting researchers in advancing novel drug solutions in this critical area of healthcare.
Obsidian Sensors
Grant in 2022
Obsidian Sensors is a company based in La Jolla, California, founded in 2017, that specializes in developing glass microelectromechanical systems (MEMS) aimed at enhancing the thermal sensor industry. Their technology utilizes infrared imaging for various applications, including security cameras and autonomous vehicles. By focusing on manufacturing processes that lower costs while maintaining or exceeding industry standards, Obsidian Sensors provides businesses with an efficient alternative to traditional silicon MEMS-based sensors.
California Lutheran University Endowment
Grant in 2022
California Lutheran University, located in Thousand Oaks, California, emphasizes a personalized educational experience through small class sizes and dedicated faculty who foster open-mindedness among undergraduate and graduate students. The university is committed to helping students pursue their passions and discover their purpose, ultimately preparing them to make meaningful contributions to their communities and the world. In 2014, California Lutheran University established a multi-purpose entrepreneurship center to support education, co-working, and start-up incubation. Additionally, the university manages an endowment fund that finances scholarships, professorships, and academic programs, with its assets overseen by the executive management team.
Acrigen Biosciences
Grant in 2022
Acrigen Biosciences focuses on enhancing the safety and efficacy of gene editing technologies, particularly those based on the CRISPR-Cas system. Founded in 2019 and headquartered in Berkeley, California, the company develops innovative solutions that aim to produce effective in vivo drug therapies to combat various diseases. Acrigen's proprietary technologies include Acro proteins that regulate the CRISPR-Cas gene editing process and an advanced bioinformatics discovery software platform that identifies suitable CRISPR systems for human therapeutic applications. Through these advancements, Acrigen Biosciences seeks to improve the precision, efficacy, and safety of genetic therapies, ultimately contributing to the potential prevention and cure of debilitating diseases.
PHYTunes
Grant in 2022
PHYTunes, based in Palo Alto, California, addresses mobility challenges and handover interruptions for various applications, including robotics, automated mobile robots, automated guided vehicles, VoIP, and mobile real-time video. The company has developed a patented technology that creates a Single Frequency Wi-Fi Network capable of covering spaces up to 100,000 square feet, offering deployment at a significantly lower cost compared to traditional WLAN providers. Additionally, PHYTunes is working on a converged Wi-Fi and mid-band 5G solution for private networks, allowing for the simultaneous distribution of both network types across multiple carriers. This innovative approach utilizes existing wire-line infrastructure, such as telephone lines and fiber-optic cables, to enhance the coverage of high-frequency mobile systems, thus enabling cellular network providers and businesses to improve connectivity for their customers.
InvVax
Grant in 2022
InvVax, Inc. is a vaccine development company based in Los Angeles, California, founded in 2012. The company focuses on creating innovative vaccines, with its primary product being a universal influenza vaccine aimed at preventing pandemics. Utilizing a proprietary platform, InvVax's technology analyzes influenza proteins to address virus mutations, thereby enhancing the effectiveness of vaccines. In addition to its work on influenza, InvVax is exploring vaccine candidates for other viral infections, including HIV, Hepatitis B, and Hepatitis C.
Ambi Robotics
Grant in 2022
Ambi Robotics is an artificial intelligence and robotics company founded in 2018 and based in Berkeley, California. The company focuses on developing advanced AI-powered robotic systems aimed at enhancing e-commerce operations and simplifying supply chain processes. Ambi Robotics offers a range of innovative solutions, including a robotic put wall, a configurable modular kitting line, and a sophisticated robot operating system that utilizes simulation-to-reality technology. These systems are designed to improve operational accuracy and efficiency while helping clients reduce costs, ultimately allowing human workers to focus on more complex tasks.
DNALite Therapeutics
Grant in 2021
DNALite Therapeutics, Inc. is a biopharmaceutical company focused on developing gene therapy treatments specifically for the gastrointestinal tract. Founded in 2016 and based in San Francisco, California, DNALite utilizes innovative oral lipid nanoparticle technology to deliver mRNA and pDNA directly to intestinal stem cells. This approach targets the underlying causes of diseases such as Familial Adenomatous Polyposis, a hereditary form of colorectal cancer that often necessitates invasive surgeries in adolescents. By enabling the intestinal tract to secrete therapeutic proteins into the bloodstream, DNALite aims to transform conventional protein biologics into oral medications, potentially improving patient outcomes and accessibility to treatment.
Rubi Laboratories
Grant in 2021
Rubi Laboratories is a California-based company that specializes in the development of technology to manufacture carbon-negative textiles. The firm utilizes innovative sustainable solutions to convert carbon emissions into natural fibers, resulting in biodegradable textiles. Its technology directly synthesizes threads, providing a natural resource for the production of viscose that is carbon-negative, as well as being water-chemical, land-neutral, traceable, and environmentally friendly. Rubi Laboratories aims to address the environmental impact of textile manufacturing by offering a more sustainable alternative in the industry.
EYSZ
Grant in 2021
EYSZ is a digital health software company based in Piedmont, California, founded in 2018. It specializes in detection algorithms that utilize oculometric and facial biometric data to reliably detect seizures and assist in the diagnosis and management of brain disorders, including epilepsy, ADHD, and depression. By employing machine learning techniques, EYSZ's software not only detects seizures but also predicts their occurrence. The platform is designed to interface and integrate with various eye-tracking systems, such as smart glasses, and therapeutic devices like neuromodulation tools, thereby enhancing the ability of clinicians to monitor and manage the neurological health of their patients effectively.
Vulcan Biologics
Grant in 2021
Vulcan Biologics is a biotechnology company based in Irvine, California, established in 2019. It specializes in the modulation of the microbiome through the use of bacteriophages, which are viruses that specifically infect bacteria without harming human cells. This innovative platform aims to achieve stable and persistent changes in the gut microbiome, facilitating the treatment of gluten-related disorders such as gluten sensitivity and celiac disease. By altering the composition of gut bacteria, Vulcan Biologics enables healthcare providers to offer targeted therapeutic solutions for individuals affected by these conditions.
Foli Research
Grant in 2021
Foli Research, founded in 2019 and located in Berkeley, California, specializes in advanced manufacturing services aimed at addressing engineering challenges. The company employs first principles analysis and computational design to deliver effective solutions, enabling manufacturers and the energy sector to achieve their growth objectives. Through its innovative approach, Foli Research supports engineers in overcoming complex problems, thereby enhancing efficiency and effectiveness in their operations.
Synvivia
Grant in 2021
Synvivia, Inc. is a biotechnology company founded in 2016 and based in Berkeley, California. It specializes in developing synthetic biology products, particularly ON-OFF switches for genetically engineered organisms. These protein switches can be controlled by small molecules, allowing for precise manipulation of biological functions. By integrating these switches into organisms, Synvivia aims to create engineered life forms that can be effectively used in healthcare. The company also focuses on generating biosensors that enhance enzymatic activities, facilitating easier disease diagnosis and enabling healthcare providers to deliver appropriate treatments.
Epirus
Grant in 2021
Epirus, Inc. is a technology company based in Hawthorne, California, specializing in the design and development of advanced defense systems that utilize artificial intelligence and directed energy. Founded in 2018, the company focuses on creating solid-state, software-defined high-power microwave solutions aimed at countering unmanned aircraft systems and other asymmetric threats. Its flagship product, ELECTROMAGNETIC PULSE, serves as a counter-infrastructure solution that can simultaneously target multiple threats, effectively neutralizing drones and swarms. By integrating AI and machine learning with advanced electronics, Epirus enhances the detection and tracking of objects of interest, offering innovative capabilities in electronic warfare and power management for both defense and commercial sectors.
Envivo Bio
Grant in 2021
Envivo Bio develops a non-invasive device that collects microbiome samples from all regions of the human gastrointestinal tract. The company is based in San Carlos, California.
Swift Solar
Grant in 2021
Swift Solar Inc. is a company that designs and manufactures lightweight solar panels and systems, focusing on advanced solar technology. Established in 2017 and headquartered in San Carlos, California, with an additional site in Golden, Colorado, Swift Solar specializes in perovskite solar cells, which are engineered to be more efficient and cost-effective than conventional solar panels. The company’s innovative approach involves creating ultra-thin perovskite films that absorb various parts of the solar spectrum, resulting in high-efficiency tandem solar cells. These cells not only enhance solar conversion efficiency but also provide significant weight advantages, making them suitable for applications in aerospace, automotive, and building sectors. Swift Solar emphasizes domestic manufacturing and utilizes abundant raw materials to ensure scalability in its operations.
STL Scientific
Grant in 2021
STL Scientific develops a non-invasive screening tool for detecting overweight trucks on the road in real-time. The company's headquarters are in Temple City, California.
Fortiphyte
Grant in 2021
Fortiphyte offers agricultural protection products that help to protect crops from disease and reduce fungicide use. The company was founded in 2017 and is based in Berkeley, California.
Serinus Labs
Grant in 2021
Serinus Labs, Inc. is a manufacturer of nano-scale silicon gas sensors, established in 2017 and located in Berkeley, California. The company specializes in developing integrated chip-scale gas sensors tailored for various industries, including health and safety, automotive, consumer electronics, and healthcare. Serinus Labs offers custom solutions for both established and emerging gas sensor markets, focusing on applications such as Li-ion battery state-of-health monitoring. Their ultra-low-power trace gas sensors contribute to enhancing battery intelligence, particularly in electric vehicles, addressing critical needs in strategic markets.
Frontier Bio
Grant in 2021
Frontier Bio Corporation, based in Oakland, California, develops and manufactures advanced bioprinting technologies to create lab-grown human tissues. Established in 2018, the company offers the FLUX-1, a 3D bioprinter that integrates conventional bioprinting methods with electro-hydrodynamic printing capabilities. This technology enables the production of complex tissues, such as skin, cartilage, and bone, while also facilitating drug toxicity testing, tissue implants, drug screening, and disease modeling. Frontier Bio aims to replace animal studies with ethically developed human tissues, ultimately working towards eliminating the organ transplant waitlist and improving patient outcomes. The company focuses on achieving complete cell survivability during the printing process, ensuring the viability of the printed tissues for various medical applications.
Quintessent
Grant in 2021
Quintessent Inc., founded in 2019 and based in Santa Barbara, California, specializes in the commercialization of quantum dot-based lasers and photonic integrated circuits. The company focuses on developing optical connectivity technology that enhances large-scale computing systems. By utilizing advanced semiconductor materials and innovative laser architectures, Quintessent's solutions facilitate the scaling of high-bandwidth communication channels within optical networks. This technology supports applications in optical networking, deep learning systems, and sensing, positioning Quintessent at the forefront of advancements in these critical areas.
Ecate
Grant in 2021
Ecate, founded in 2020 and based in Los Angeles, California, is focused on developing advanced medical devices that create neural interfaces to bridge the gap between human and machine intelligence. The company utilizes nanoparticles and nanotechnology to engineer bi-directional neural interfaces equipped with customized nanopatterned electrodes. This innovative technology aims to restore sensory and motor communication for individuals with paralysis, enabling them to regain control of lost functions and improve their quality of life.
TRGel
Grant in 2021
TRGel, founded in 2010 and located in Irvine, California, specializes in the development of glucose-based biopolymers designed to serve as an alternative to calcium alginate for encapsulation purposes. The company’s biopolymers are crafted from biocompatible materials, which encompass thermoresponsive hydrogels with adjustable gelation temperatures. These innovative biopolymers enable researchers to utilize them effectively as vehicles for drug delivery, expanding the possibilities for applications in various fields.
Andluca
Grant in 2021
Andluca is a company that specializes in the development of innovative smart glass and smart window products, utilizing UV light and solar energy to enhance energy efficiency in buildings and homes. Founded in 2017 as a spin-out from Princeton University, Andluca has established its operations in New York and California. The company focuses on advanced solar materials, coatings, and embedded systems that enable glass and window products to respond intelligently to environmental changes. Its products can be installed like conventional windows or facades, offering a cost-effective solution that reduces installation time and the carbon footprint typically associated with traditional smart window technologies. Through partnerships with window and facade manufacturers, Andluca provides a diverse range of smart glass options to its clients.
Lucata
Grant in 2021
Lucata Corporation specializes in developing advanced hardware and software technology to enhance memory utilization for various industries. Founded in 2008 and headquartered in New York, with additional offices in South Bend, Indiana, and Palo Alto, Lucata produces motherboards, node cards, and memory servers designed for high-performance analytics. The company employs patented migrating thread technology to enable organizations to perform extensive multi-hop analytics and graph analysis on massive databases, facilitating insights from complex data structures with up to one trillion vertices. Lucata's solutions cater to sectors such as financial services, cybersecurity, healthcare, and telecommunications, allowing users to leverage existing graph database software for deeper analysis without the need for extensive software layers. The company's architecture is energy-efficient, supports linear performance scaling, and significantly reduces latency, making it a powerful option for organizations tackling big data challenges.
Lumina Instruments
Grant in 2021
Lumina Instruments specializes in the development of laser optical scanning equipment tailored for the expanding glass market in high-tech industries. Founded in 2019 and based in San Jose, California, the company focuses on enhancing production efficiency through its advanced technology. Their equipment offers thin-film defect detection capabilities, allowing businesses to effectively map and classify a variety of substrates, including transparent, translucent, and opaque materials of diverse shapes. This innovation supports improved yield and management in manufacturing processes, catering to the needs of modern high-tech applications.
Intellerce
Grant in 2021
Intellerce is a San Diego-based company founded in 2020 that specializes in developing a video streaming platform aimed at significantly lowering the costs associated with streaming video-on-demand content. The platform leverages artificial intelligence to minimize reliance on data centers and Content Distribution Networks (CDNs), which not only reduces streaming expenses but also decreases energy consumption and the carbon footprint of cloud computing infrastructures. By optimizing these processes, Intellerce enables video companies to provide a high-quality streaming experience for their users while promoting sustainability in the digital content delivery space.
Novel Farms
Pre Seed Round in 2021
Novel Farms, Inc. is a company based in Berkeley, California, founded in 2020, that specializes in the production of cell-based meat products aimed at ethical consumers. Utilizing microbial fermentation and proprietary tissue engineering technology, Novel Farms develops cruelty-free and affordable 3D bioscaffolds, which enable the creation of structured meat products that replicate the taste and texture of traditional gourmet meats. The company focuses on making cell-based meat a desirable culinary option for a new generation of consumers, promoting a more sustainable and ethical approach to meat consumption. Through its innovative methods, Novel Farms seeks to achieve price parity with conventional meat, making its offerings accessible to a broader audience while transforming the future of food.
Revelata
Grant in 2021
Revelata develops an artificial intelligence platform for extracting data from complex financial documents. It's first product, deepKPI, automatically surfaces hard-to-get KPI time series that are buried within billions of pages of SEC filings. The company was founded in 2020 and is headquartered in Palo Alto, California.
Prisms VR
Grant in 2021
Prisms VR is a STEM education platform based in San Francisco, California, founded by Anurupa Ganguly. The company specializes in creating immersive educational experiences using virtual reality technology. Its software features modules designed to provide realistic 3D environments that facilitate problem-solving and enhance understanding of complex concepts. These modules support content remediation and reinforce lessons learned in class, making them valuable for both in-person and remote learning settings. The platform aims to assist teachers and parents in teaching and fostering spatial thinking skills in students, ultimately enriching the educational experience.
Paramita Therapeutics
Grant in 2021
Paramita Therapeutics is a biotech company established in 2018 and based in San Diego, California. The company is dedicated to developing innovative therapeutics for cancer and infectious diseases. It specializes in efficiently transitioning new therapeutics into clinical settings using a patented, multifunctional chemical platform. This approach allows Paramita Therapeutics to create multivalent drug conjugates derived from recognized and approved molecules with established safety and toxicology profiles. By leveraging its expertise, the company aims to provide patients with access to effective cancer treatments and dual-function therapeutic and vaccine products.
Kapalya
Grant in 2021
Kapalya Inc. specializes in developing a mobile application that facilitates secure access to corporate and cloud servers for both Apple iOS and Android devices. The Kapalya app enables users to navigate and transfer files between various platforms, including corporate SharePoint farms, Windows file shares, and cloud storage applications, utilizing fingerprint recognition for enhanced security. The company also provides real-time encryption key management, ensuring the protection of sensitive files both at-rest and in-transit across multiple endpoints and cloud platforms. Kapalya's services cater to chief information officers, chief information security officers, executives, and enterprise users, allowing them to securely manage and share encrypted files. Founded in 2015, Kapalya is headquartered in Honolulu, Hawaii, with an additional office in Berkeley, California.
Novel Farms
Grant in 2021
Novel Farms, Inc. is a company based in Berkeley, California, founded in 2020, that specializes in the production of cell-based meat products aimed at ethical consumers. Utilizing microbial fermentation and proprietary tissue engineering technology, Novel Farms develops cruelty-free and affordable 3D bioscaffolds, which enable the creation of structured meat products that replicate the taste and texture of traditional gourmet meats. The company focuses on making cell-based meat a desirable culinary option for a new generation of consumers, promoting a more sustainable and ethical approach to meat consumption. Through its innovative methods, Novel Farms seeks to achieve price parity with conventional meat, making its offerings accessible to a broader audience while transforming the future of food.
rivieh
Grant in 2021
Rivieh is a technology company based in Los Angeles, California, that specializes in developing hardware solutions to convert properties into smart buildings. Founded in 2018, Rivieh's platform integrates essential components for controlling lighting, heating, ventilation, air conditioning (HVAC), music, and smart assistants. This integration allows hoteliers to provide guests with a seamless smart home experience while simultaneously reducing energy consumption and lowering maintenance costs.
Semiotic AI
Grant in 2021
Semiotic AI is a company that specializes in encrypted computing services utilizing Fully Homomorphic Encryption (FHE) to enhance data security and privacy in cloud environments. By allowing organizations to perform data analytics on sensitive information without compromising its integrity, Semiotic AI addresses critical concerns related to data protection. The company's technology also safeguards proprietary models by encrypting them prior to deployment. Founded in 2020 and headquartered in Los Altos, California, Semiotic AI aims to play a significant role in the evolving landscape of cloud computing, artificial intelligence, and emerging technologies. In addition, the company develops automated decision-making tools that leverage AI and cryptography to facilitate decentralized markets on the blockchain, enhancing price efficiency and usability for businesses and consumers alike. The founders bring extensive experience in cryptography and AI, positioning Semiotic AI as a key player in the future of secure data management.
Tacit Therapeutics
Grant in 2021
Tacit Therapeutics is a biotechnology company focused on developing RNA-targeted treatments to address genetic diseases. Founded in 2021 and based in South San Francisco, California, the company utilizes pre-existing components of human cells to create innovative, non-immunogenic methods for repairing mutated genes. By offering a broadly applicable approach to gene modification, Tacit Therapeutics aims to provide effective solutions for genetic conditions that were previously deemed untreatable, thereby enabling advancements in the treatment of devastating diseases.
Cruz Foam
Seed Round in 2021
Cruz Foam, Inc. is a manufacturer of structural foams that addresses the issue of plastic pollution by providing eco-friendly alternatives to conventional petroleum-based foams. Founded in 2017 and based in Santa Cruz, California, the company transforms chitin, a biopolymer derived from shrimp shells, into biodegradable packaging materials. Cruz Foam's products are used across various industries, including consumer packaging, electronics, automotive, and shipping, offering scalable and compostable solutions that can be integrated into existing supply chains at competitive costs. By focusing on sustainability, Cruz Foam aims to empower industry leaders to adopt environmentally friendly practices and reduce reliance on single-use plastics.
Cruz Foam
Grant in 2021
Cruz Foam, Inc. is a manufacturer of structural foams that addresses the issue of plastic pollution by providing eco-friendly alternatives to conventional petroleum-based foams. Founded in 2017 and based in Santa Cruz, California, the company transforms chitin, a biopolymer derived from shrimp shells, into biodegradable packaging materials. Cruz Foam's products are used across various industries, including consumer packaging, electronics, automotive, and shipping, offering scalable and compostable solutions that can be integrated into existing supply chains at competitive costs. By focusing on sustainability, Cruz Foam aims to empower industry leaders to adopt environmentally friendly practices and reduce reliance on single-use plastics.
Caribou Biofuels
Grant in 2021
Caribou Biofuels manufactures biofuels for the conversion of biomass into fuels. The company was established in 2017 and is based in Modesto, California.
Carrisan Technologies
Grant in 2021
Carrisan Technologies is a food technology company established in 2019 and located in Davis, California. The company specializes in developing innovative antimicrobial solutions aimed at preventing the spread of foodborne illnesses and minimizing food losses. Its technology encompasses antimicrobial coatings for equipment surfaces, methods for biofilm removal, and sanitation processes for food production. Carrisan Technologies serves various sectors, including agriculture, food processing, and foodservice, providing effective measures to combat cross-contamination in these industries.
Oculogenex
Grant in 2021
Oculogenex is a biopharmaceutical company based in La Habra, California, established in 2020. The company specializes in developing gene therapies specifically aimed at treating retinal disorders. Its innovative approach involves ocular regenerative gene therapy that protects retinal pigment epithelial cells from oxidative stress-induced damage, which is a contributing factor to macular degeneration. By focusing on these therapies, Oculogenex aims to enhance the detection and treatment of various retinal disorders, ultimately supporting researchers in advancing novel drug solutions in this critical area of healthcare.
Rebel Research
Grant in 2021
Rebel Research, founded in 2020 and based in Torrance, California, focuses on developing innovative technologies to tackle significant challenges in energy and environmental sustainability. The company operates an environmental technology laboratory that fosters creativity and idea generation, allowing scientists and engineers to explore and implement solutions for a sustainable and equitable future. Through its commitment to addressing pressing global issues, Rebel Research aims to contribute positively to both the environment and society.
Pomodyne
Grant in 2021
Pomodyne is a technology company based in Mountain View, California, focused on transforming fruit crop cultivation. Founded in 2019, the company employs plant biotechnology and controlled environment agriculture to tackle significant challenges such as climate change, food safety, and food security. By innovating agricultural practices, Pomodyne aims to enhance the efficiency and sustainability of the agriculture industry, ultimately contributing to a more secure food system.
Benchmark Labs
Grant in 2021
Benchmark Labs, based in San Francisco, California, specializes in AI-driven weather forecasting tailored for the agricultural sector and other industries. The company delivers precise, asset-specific forecasts that help clients navigate the challenges posed by changing weather patterns. By utilizing Internet of Things (IoT) sensors from various manufacturers, Benchmark Labs provides critical data that enables organizations to optimize renewable energy generation and manage water allocation effectively. The accuracy of their forecasts is essential for maintaining infrastructure and operational efficiency in the face of increasing weather variability.
Coreshell
Grant in 2021
Coreshell Technologies, Inc. is a company focused on developing advanced lithium-ion batteries, primarily targeting the electric vehicle and grid storage markets. Founded in 2017 and based in Berkeley, California, Coreshell has pioneered a nanolayer thin-film coating technology that addresses the degradation issues commonly faced by rechargeable batteries. This innovative coating protects battery electrodes from chemical reactions that can diminish capacity and safety, thereby enhancing the overall performance and durability of the batteries. By seamlessly integrating into existing manufacturing processes, Coreshell's technology aims to significantly improve battery capacity, safety, and cost-effectiveness, facilitating a smoother transition to electric transportation and renewable energy solutions.
Cartilage
Grant in 2021
Cartilage is a company based in Irvine, California, founded in 2019, that focuses on developing tissue-engineered products for the regeneration of cartilage. The company addresses both focal and large cartilage defects by utilizing a viscous injectable solution designed to enhance cartilage integration. This innovative approach aims to treat early signs of cartilage injury, allowing patients to heal effectively without the limitations associated with existing treatment options.
NeyroblastGX
Grant in 2021
NeyroblastGX is a biotechnology company established in 2020 and based in Murrieta, California, focused on developing theranostic products aimed at treating neurodegenerative and infectious diseases. The company’s product offerings include a blood-based biomarker diagnostic for Alzheimer's, genetically engineered dendritic cells designed to eliminate custom-made human organoids for drug screening, cellular toxicity assessment, and disease pathology. Additionally, NeyroblastGX develops an oral supplement intended to enhance protective immunity, providing patients with a comprehensive portfolio of diagnostics, drugs, and therapies to combat life-threatening conditions.
VeriSIM Life
Grant in 2021
VeriSIM Life, Inc. is a biotechnology company based in San Francisco, California, established in 2017. It specializes in developing disease-specific biosimulation models that utilize artificial intelligence to predict the clinical outcomes of new drugs prior to clinical trials. The company offers a range of tailored solutions designed for pre-clinical and clinical programs, all centered around its validated BIOiSIM platform, which accommodates small molecules, large molecules, and viruses. By replacing traditional animal testing with sophisticated software simulations, VeriSIM Life aims to enhance the accuracy and efficiency of drug development, ultimately contributing to increased human life expectancy and the personalization of healthcare treatments.
Florica Therapeutics
Grant in 2021
Florica Therapeutics, founded in 2019 and based in Livermore, California, focuses on developing exosome-based therapeutics aimed at extending lifespan and preventing age-related diseases. The company specializes in delivering drugs to the brain, offering innovative treatment alternatives for serious conditions such as leukemia and Tay-Sachs disease. By advancing these therapeutics, Florica Therapeutics seeks to improve patient outcomes and enhance the quality of life for individuals affected by terminal illnesses.
Labrador Systems
Grant in 2021
Labrador Systems, Inc. is a technology company based in Oak Park, California, focused on developing assistive robots to enhance daily living. Founded in 2017, the company aims to improve the quality of life for individuals by creating a new generation of personal robots that address everyday needs. By leveraging advanced robotics hardware and software, Labrador Systems designs practical applications to support home health and assist individuals in their daily activities.
GRI Bio
Grant in 2021
GRI Bio, Inc. is a clinical-stage biotechnology company based in La Jolla, California, focused on developing innovative therapies for liver disease and autoimmune disorders. The company specializes in harnessing Natural Killer T (NKT) cell-based therapies to address dysregulated immune responses associated with inflammatory and fibrotic diseases. One of its primary product candidates, GRI-0621, is an oral small molecule that inhibits type 1 NKT cells, aiming to restore immune system balance in patients with liver conditions. Additionally, GRI Bio is advancing GRI-0803, an oral agonist targeting type 2 NKT cells. Established in 2009, GRI Bio is committed to discovering and commercializing effective treatments for serious health challenges linked to immune system dysfunction.
Fathhome
Grant in 2021
Fathhome is a company based in Oakland, California, that specializes in the development of a sanitizing device designed for the dry sanitization of various household items. Founded in 2015, Fathhome's innovative device employs air pressure and ionization technology to effectively sanitize items such as packages, clothes, shoes, helmets, personal protective equipment, and electronic devices like phones and computers. This approach allows users to eliminate harmful viruses and bacteria without the need for water, detergents, or chemicals, providing a convenient and effective solution for maintaining cleanliness in everyday life.
Biomilitus
Grant in 2021
Biomilitus is a biotechnology company founded in 2019 and based in Sacramento, California. The company focuses on utilizing insect larvae to produce animal feed, aiming to reduce land usage and lower carbon emissions. By employing low-cost agricultural by-products as feed for the insects, Biomilitus offers a sustainable alternative to traditional animal-feed ingredients that are high in protein and fat and rich in essential amino acids. This innovative approach not only addresses waste management by decreasing transportation costs associated with agricultural by-products but also contributes to a more environmentally friendly animal feed solution.
Discrete Lattice Industries
Grant in 2021
Discrete Lattice Industries, founded in 2020 and based in Laguna Beach, California, specializes in the development of programmable and cellular materials designed to minimize dependence on fixed tooling. The company focuses on creating customizable products through the discrete assembly of modular and building-block components. This innovative approach not only enhances material efficiency but also improves structural performance. Discrete Lattice Industries aims to serve various sectors, including infrastructure, transportation, and renewable energy, by providing solutions that increase operational efficiency and adaptability in these markets.
Seven Biosciences
Grant in 2020
Seven Biosciences provides drug discovery platforms for G-protein coupled receptors. The company, based in Davis, California, was founded by Grace Mizuno and Lin Tian.
Symbrosia
Grant in 2020
Symbrosia is a California-based cleantech startup founded in 2018 that focuses on reducing livestock methane emissions through innovative feed supplements. The company has developed a proprietary product called Seagraze, which is derived from fast-growing Asparagopsis seaweed strains. By incorporating this seaweed into cattle feed, Symbrosia enables ranchers and livestock producers to significantly lower greenhouse gas emissions associated with livestock farming. Through its efforts, Symbrosia aims to promote sustainable agricultural practices while addressing environmental challenges linked to livestock methane production.
Flotherm
Grant in 2020
Flotherm is a company based in Los Angeles, California, that specializes in the development of a thermal compression device aimed at maintaining normothermia during surgical procedures. This innovative device is designed to provide perioperative warming without obstructing access to the surgical site or increasing the risk of contamination. By integrating dynamic compression with lower-limb warming, Flotherm's technology allows surgeons to effectively manage the risks associated with accidental hypothermia and deep-vein thrombosis. The device enhances perioperative compliance while seamlessly fitting into existing surgical workflows.
Monterey Bay Aquariam Research Institute
Grant in 2020
MBARI was founded in 1987 by engineer David Packard. Among his many accomplishments, David Packard (along with William Hewlett) started the Hewlett-Packard Company, a maker of computers and electronic equipment. After helping his daughters, Julie Packard and Nancy Burnett, develop the Monterey Bay Aquarium in 1984, David Packard established MBARI as a private, not-for-profit oceanographic research center, with offices and laboratories in Pacific Grove, on the Monterey Peninsula.
ClimateAI
Grant in 2020
ClimateAI, Inc. is an enterprise climate platform established in 2017 and headquartered in San Francisco, California. The company specializes in providing cloud-based software solutions that help businesses assess and adapt to physical climate risks. Its platform utilizes a climate decision engine and open-source satellite imagery, applying statistical analysis and machine learning techniques to deliver insights for various sectors, including agriculture, energy, construction, and asset management. By enabling users to make informed decisions regarding risk management and investment valuations, ClimateAI aims to climate-proof the global economy, thereby minimizing losses to lives, livelihoods, and the environment.
Sown To Grow
Grant in 2020
Sown To Grow, Inc. is a company based in Oakland, California, that specializes in a student goal-setting and reflection platform designed to enhance student well-being and academic performance. Founded in 2015, the platform empowers students to establish personal learning goals, track their progress, and engage in reflective practices to foster a growth mindset and student agency. Additionally, it offers various assignments from third-party programs that facilitate learning and enable teachers to monitor student growth effectively. Through this approach, Sown To Grow aims to support both students and educators in the learning process.
Cactus Medical
Grant in 2020
Cactus Medical provides physicians with a standardized method for evaluating middle ear effusion. The company was founded in 2017 and is headquartered in Irvine, California.
Dascena
Grant in 2020
Dascena, Inc. is a healthcare technology company based in Oakland, California, that specializes in developing machine learning algorithms aimed at enhancing patient care and early disease intervention. Founded in 2018, Dascena focuses on creating algorithmic software that processes electronic health record data to predict critical conditions such as acute decompensation, sepsis, and acute kidney injury. By leveraging extensive clinical research, the company provides tools that support clinical decision-making, facilitate point-of-care diagnostics, and serve as biopharma companion diagnostics. Dascena's innovations address significant unmet healthcare needs, ultimately aiming to improve care outcomes and save lives through timely and accurate interventions.
Acrigen Biosciences
Grant in 2020
Acrigen Biosciences focuses on enhancing the safety and efficacy of gene editing technologies, particularly those based on the CRISPR-Cas system. Founded in 2019 and headquartered in Berkeley, California, the company develops innovative solutions that aim to produce effective in vivo drug therapies to combat various diseases. Acrigen's proprietary technologies include Acro proteins that regulate the CRISPR-Cas gene editing process and an advanced bioinformatics discovery software platform that identifies suitable CRISPR systems for human therapeutic applications. Through these advancements, Acrigen Biosciences seeks to improve the precision, efficacy, and safety of genetic therapies, ultimately contributing to the potential prevention and cure of debilitating diseases.
Raydiant Oximetry
Grant in 2020
Raydiant Oximetry, Inc. is a medical device company founded in 2015 and headquartered in Mountain View, California. The company focuses on improving childbirth outcomes for mothers and infants by developing a low-cost, non-invasive device that monitors fetal oxygen levels during labor. This innovative technology aims to provide real-time insights into fetal oxygenation, which can help clinicians make informed decisions and reduce the risks associated with childbirth, such as birth injuries and unnecessary cesarean sections. By enhancing patient care and potentially lowering healthcare costs, Raydiant Oximetry's device addresses critical needs in maternal and fetal health.
Intact Therapeutics
Grant in 2020
Intact Therapeutics is a biotechnology company based in Belmont, California, founded in 2015. The company focuses on developing a thermosensitive drug delivery platform, specifically smart gels designed for the treatment of gastrointestinal disorders, including ulcerative colitis. Their proprietary gel technology remains in a liquid state at room temperature, transforming into a mucoadhesive gel at body temperature. This innovative approach allows for targeted drug delivery, providing localized concentrations of medication while minimizing systemic exposure. The gel's design enhances drug retention, efficacy, and patient comfort, offering a painless healing option for individuals suffering from inflammatory bowel diseases.
Sinovia
Grant in 2020
Sinovia Technologies, founded in 2011 and based in San Francisco, specializes in the manufacture of transparent electrodes and flexible printed organic light-emitting diode (OLED) displays. The company employs advanced roll-to-roll printing processes, similar to those used in label and packaging production, to create cost-competitive OLED displays for a variety of applications, including touch screens for mobile devices and IoT indicators. Sinovia's products are noted for being thinner, brighter, and more energy-efficient than traditional LED and LCD displays, allowing for innovative design possibilities such as integration on curved surfaces. The company focuses on delivering high-quality, durable electronics that meet the evolving needs of hardware designers.
Koya Medical
Grant in 2020
Koya Medical, Inc., founded in 2018 and based in Oakland, California, specializes in developing innovative therapeutic devices aimed at treating cancer-related chronic lymphedema and various venous diseases. The company focuses on creating wearable technology that delivers active compression therapy, which is designed to enhance movement and mobility for patients. Koya Medical's approach offers a personalized alternative to traditional compression methods, utilizing a sensor-based closed-loop system to provide tailored compression patterns. This technology addresses the needs of patients suffering from conditions such as lymphedema, chronic edema, and chronic venous insufficiency, thereby improving their quality of care and overall treatment outcomes.
ChameleonCloud
Grant in 2020
Cloud services have become ubiquitous to all major 21st century economic activities. However, cloud services and technologies can be significantly more powerful than they are now. A persistent barrier to further advancement has been the lack of a large-scale and open cloud research platforms. With funding from the National Science Foundation (NSF), the Chameleon project will provide such a large-scale platform to the open research community allowing them explore transformative concepts in deeply programmable cloud services, design, and core technologies. Chameleon will allow users to explore problems ranging from the creation of Software as a Service to kernel support for virtualization. This broad range of supported research includes many other areas such as developing Platforms as a Service, creating new and optimizing existing Infrastructure as a Service components, investigating software-defined networking, and optimizing virtualization technologies. The Chameleon testbed, will be deployed at the University of Chicago and the Texas Advanced Computing Center and will consist of 650 multi-core cloud nodes, 5PB of total disk space, and leverage 100 Gbps connection between the sites. While a large part of the testbed will consist of homogenous hardware to support large-scale experiments, a portion of it will support heterogeneous units allowing experimentation with high-memory, large-disk, low-power, GPU, and co-processor units. The project will also leverage existing FutureGrid hardware at the University of Chicago and the Texas Advanced Computing Center in its first year to provide a transition period for the existing FutureGrid community of experimental users. To support the broad range of experiments experiments described above, the project will support a graduated configuration system allowing full user configurability of the software stack, from provisioning of bare metal and network interconnects to delivery of fully functioning cloud environments. A special feature of Chameleon is that it provides for an exceptionally close integration of clouds and networks, which substantially enhances the capabilities of both. In addition, to facilitate experiments, Chameleon will support a set of services designed to meet researchers needs, including support for experimental management, reproducibility, and repositories of trace and workload data of production cloud workloads. The project is led by the Computation Institute at the University of Chicago and partners from the Texas Advanced Computing Center at the University of Texas at Austin, the International Center for Advanced Internet Research at Northwestern University, the Ohio State University, and University of Texas at San Antonio, comprising a highly qualified and experienced team. The team includes members from the NSF supported FutureGrid project and from the GENI community, both forerunners of the NSFCloud solicitation under which this project is funded. Chameleon will also form a set of partnerships with commercial and academic clouds, such as Rackspace, CERN and Open Science Data Cloud (OSDC), and will partner with other testbeds, notably GENI and INRIA's Grid'5000 testbed.
EyePredict
Grant in 2020
EyePredict is a developer of commercializing predictive attention software which is intended to improve health commonly for neurological and psychiatric conditions to allow marketplaces to optimize commercial displays. The company intends to improve decision making for attention development which reflects upon patterns in mental dysfunction using neuroscience based software technology to predict visual attention. EyePredict was established by Ran Carmi in Los Angeles, California.
Maui Imaging
Grant in 2020
Maui Imaging, Inc., established in 2006 and located in Sunnyvale, California, specializes in the manufacture of advanced ultrasound imaging devices. The company offers innovative technology that enables imaging through and around various materials, including bones, metals, plastics, gas, and soft tissue. Utilizing techniques such as Computed Echo Tomography and adaptive beam forming, Maui Imaging's systems capture 3D images that traditional ultrasound methods cannot achieve. This capability enhances diagnostic and treatment options within the healthcare industry, providing valuable insights for medical professionals.
WideSense
Grant in 2020
WideSense is dedicated to promoting the adoption of clean and efficient mobility through its innovative solutions for electric vehicle fleet management. The company offers a physics-based, AI-powered software platform that assists planners and operators in designing, deploying, and managing electric vehicle fleets effectively. Its services focus on ensuring operational reliability while maximizing vehicle utilization and minimizing electricity costs. By providing tools for capital planning and continuous performance monitoring, WideSense enables fleet operators to enhance their operational efficiency and profitability. Headquartered in Berkeley, California, the company is rapidly expanding its global reach, serving major metropolitan and commercial fleet operators with expertise in software, machine learning, and fleet management.
Maverick Space Systems
Grant in 2020
Maverick Space Systems, founded in 2019 and headquartered in San Luis Obispo, California, specializes in satellite deployment hardware along with integration and launch brokering services. The company provides customized and cost-effective solutions for satellite deployment, managing development and launch campaigns for university programs, government missions, and commercial constellations. By offering seamless, turn-key services, Maverick Space Systems enables its customers to efficiently and effectively place their payloads into orbit across North America.
Obsidio
Grant in 2020
Obsidio, Inc. is a medical device company founded in 2018 and based in Solana Beach, California. The company specializes in developing shear-thinning hydrogel biomaterial technology, which is used to manufacture therapeutic devices and universal gel embolization materials. This technology allows for minimally invasive procedures to inject embolic materials through catheters, effectively stopping undesirable blood flow in vessels throughout the body. Obsidio's products are applicable in various medical scenarios, including the treatment of hemorrhages, aneurysms, and tumors, as well as managing conditions related to coagulopathy. By focusing on interventional radiology and oncology, Obsidio aims to provide precise and durable solutions for vascular occlusion.
Oncodisc
Grant in 2020
Oncodisc, Inc. is a California-based company that specializes in the development of connected vascular access devices designed for oncology patients. Its flagship product is an implantable vascular access port that not only facilitates medication delivery but also monitors patients' health during high-risk outpatient therapies. The device is equipped with advanced sensors and wireless communication capabilities, allowing for real-time monitoring and early detection of complications. Oncodisc also provides data analytics solutions that alert healthcare providers to patients showing early signs of issues, which can lead to timely interventions and reduced hospitalizations. Additionally, the company offers a Remote Care Platform that includes mobile tools for validated patient-reported outcomes, telehealth services, and enhanced patient engagement. Established in 2018, Oncodisc aims to improve cancer care through innovative technology that fosters personalized treatment and better communication between patients and healthcare providers.
ACatechol
Grant in 2020
ACatechol, founded in 2016 and based in Pasadena, California, specializes in the development of biological-protein-based adhesives and biomimetic surface technologies. The company's innovative products are designed to prevent the spread of diseases by utilizing nanocomposite coatings and surface modifications applicable to various materials such as medical devices, implants, and textiles. These advanced coatings are effective in eliminating a wide range of bacteria and viruses, even in moist conditions. This capability enables the production of underwater glues, adhesives, coatings, and primers, offering a safer and more efficient alternative to traditional silane-based grafting methods, which can be slow, toxic, and inconsistent.
Evolution Devices
Grant in 2020
Evolution Devices, Inc. is a neuro rehabilitation technology company based in Berkeley, California, focused on enhancing mobility for individuals with neurological impairments. The company’s flagship product, EvoWalk, is a bio-electronic wearable device that utilizes functional electrical stimulation and artificial intelligence to track walking patterns and personalize rehabilitation therapy. EvoWalk is designed for patients recovering from conditions such as stroke, multiple sclerosis, ALS, cerebral palsy, traumatic brain injury, and incomplete spinal cord injury. The device employs sensors that deliver electrical stimulation to leg muscles and the peroneal nerve, aiding in foot elevation during walking. This technology aims to eliminate foot drop, reduce fatigue, and minimize the risk of tripping accidents. Evolution Devices, formerly known as Foot++, Inc., was established in 2017 and rebranded in September 2019.
Resource Chemical
Grant in 2020
ReSource Chemical is a company based in Berkeley, California, focused on developing high-performance plastics derived from carbon dioxide. The company utilizes a proprietary bio-based platform to create chemicals that enable the production of environmentally friendly plastics with superior physical properties compared to traditional fossil fuel-based plastics. By converting CO2 into these innovative materials, ReSource Chemical aims to provide sustainable alternatives that do not contribute to environmental pollution.
Hubly Surgical
Non Equity Assistance in 2020
Hubly Surgical Inc. is a medical technology company focused on enhancing patient outcomes and improving the quality of care in neurosurgery. Founded in 2018 and based in San Francisco, California, with an additional office in Chicago, the company has developed an integrated electric drill system that replaces traditional free-hand techniques. This innovative device aims to reduce the rate of lethal complications associated with surgical drilling and is designed to facilitate bedside intracranial access, decreasing the reliance on operating rooms. Hubly's mission is to make its safety technology the standard of care for medical drilling, ensuring that both standard and underserved settings can benefit from improved surgical procedures.
Prisms VR
Grant in 2020
Prisms VR is a STEM education platform based in San Francisco, California, founded by Anurupa Ganguly. The company specializes in creating immersive educational experiences using virtual reality technology. Its software features modules designed to provide realistic 3D environments that facilitate problem-solving and enhance understanding of complex concepts. These modules support content remediation and reinforce lessons learned in class, making them valuable for both in-person and remote learning settings. The platform aims to assist teachers and parents in teaching and fostering spatial thinking skills in students, ultimately enriching the educational experience.
Xona Space Systems
Grant in 2020
Xona Space Systems, Inc. specializes in developing and manufacturing position, navigation, and timing (PNT) satellite solutions. Founded in 2019 and headquartered in San Mateo, California, the company is focused on creating a constellation of low-cost, low-Earth orbiting satellites designed to enhance navigation for various applications, including autonomous vehicles, unmanned aerial vehicles, and mobile robotics. Their flagship product, the Xona Pulsar, delivers high-power signals from low Earth orbit, ensuring secure and accurate navigation and timing services. This innovative approach aims to meet the demands of smart transportation and smart infrastructure, providing the resilience and precision necessary for modern intelligent systems to operate safely and efficiently at scale.
Protabit
Grant in 2020
Protabit specializes in protein engineering for various sectors, including industrial, agricultural, and healthcare applications. The company employs a unique platform technology that integrates computational modeling with high-throughput screening and directed evolution to enhance the diversity of protein sequences. This innovative approach allows Protabit to produce novel proteins tailored to specific needs. The development of their technology is supported by strategic partnerships with notable organizations, including Monsanto Company and the California Institute of Technology. Through its advanced methodologies, Protabit aims to advance the field of protein design and provide customized solutions for its clients.
Wield
Grant in 2020
Wield is a company that develops advanced prosthetic systems aimed at restoring mobility and independence for individuals with limb loss. Founded in 2020 and based in San Francisco, California, Wield's platform utilizes innovative materials and biomimetic design to create functional and aesthetically appealing prosthetics. By integrating technology that allows users to control these devices through computers, Wield empowers individuals to engage fully in their daily lives and pursue their personal goals.
Curated Networks
Grant in 2020
Curated Networks, founded in 2019 and based in Santa Cruz, California, specializes in innovative link-layer and network-layer routing solutions. The company aims to transform traditional static network configurations by introducing a dynamic approach that enhances quality of service, policy-based routing, and 5G slicing capabilities. By providing a comprehensive suite of performance and policy options within a secure, default-deny framework, Curated Networks enables network operators to adopt either centralized or distributed architectures. This approach is designed to reduce network fragility, streamline administration, and lower operational costs, thereby offering a more flexible and efficient networking solution.
Obsidian Sensors
Grant in 2020
Obsidian Sensors is a company based in La Jolla, California, founded in 2017, that specializes in developing glass microelectromechanical systems (MEMS) aimed at enhancing the thermal sensor industry. Their technology utilizes infrared imaging for various applications, including security cameras and autonomous vehicles. By focusing on manufacturing processes that lower costs while maintaining or exceeding industry standards, Obsidian Sensors provides businesses with an efficient alternative to traditional silicon MEMS-based sensors.
Foli Research
Grant in 2020
Foli Research, founded in 2019 and located in Berkeley, California, specializes in advanced manufacturing services aimed at addressing engineering challenges. The company employs first principles analysis and computational design to deliver effective solutions, enabling manufacturers and the energy sector to achieve their growth objectives. Through its innovative approach, Foli Research supports engineers in overcoming complex problems, thereby enhancing efficiency and effectiveness in their operations.
Logisic Devices
Grant in 2020
Logisic Devices manufactures power semiconductor devices. The company was founded in 2019 and is headquartered in San Jose, California.
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