National Science Foundation

Dynocardia, Inc. is a biomedical device company based in Massachusetts that specializes in wireless blood pressure measurement equipment. Founded in 2018, the company has developed a wrist-wearable device called ViTrack, which allows users to accurately and continuously measure vital health parameters, including blood pressure, heart rate, heart rhythm, and respiration rate. Utilizing an innovative optomechanical sensor, Dynocardia's technology offers a non-invasive method for blood pressure measurement, rivaling the accuracy of traditional intra-arterial measurements. The company's focus is on addressing critical unmet healthcare needs, providing a mobile, user-friendly solution for monitoring cardiovascular health.

Theromics Inc. is a biotechnology company focused on developing innovative cell therapies, particularly in the field of thermal ablation for cancer treatment. Founded in 2016 and based in West Bridgewater, Massachusetts, the company has created HeatSYNC Gel, a biopolymer thermal accelerant designed to enhance the effectiveness of microwave and radiofrequency ablation procedures. This gel improves the delivery and absorption of thermal energy in soft tissue and bone, optimizing the ablation zone's shape and volume. By increasing local tissue electrical conductivity, HeatSYNC Gel helps to prevent heat loss due to blood flow, allowing for more precise targeting of tumors and protecting surrounding healthy tissue. The gel can be administered through various methods, including syringe, laparoscope, and bronchoscope, and is intended to improve the overall efficacy of thermal ablation therapies while enabling personalized treatment approaches.

Thiozen is a company based in Belmont, Massachusetts, that specializes in innovative hydrogen gas production technology aimed at reducing greenhouse gas emissions. Founded in 2020, Thiozen employs a unique chemical process that converts hydrogen sulfide into hydrogen gas. This method not only significantly lowers greenhouse gas emissions but also allows clients to bypass the carbon emissions typically associated with hydrogen production from natural gas and the high costs linked to electrolysis. By offering a low-cost and low-emission alternative, Thiozen positions itself as a key player in the transition to cleaner energy solutions.

The Engine, established by the Massachusetts Institute of Technology (MIT) in 2016, is a venture firm focused on supporting early-stage companies that tackle significant global challenges through innovative science and engineering. The Engine prioritizes transformative ideas over immediate profitability, offering a streamlined system that accelerates the progression from concept to market. It provides a physical workspace for startups, along with essential resources such as business planning, legal assistance, and administrative support. The Engine also connects entrepreneurs with "patient capital" from like-minded investors, allowing startups to maintain greater control over their ventures. With plans to support up to 60 startups simultaneously over a 12-month period, The Engine aims to facilitate rapid development and validation of groundbreaking concepts. Additionally, it offers access to specialized equipment and lab space through the Engine Room, fostering a collaborative environment that nurtures innovation within the MIT community and beyond.

Rapid7, established in 2000, is a cybersecurity company that offers a range of solutions to help organizations proactively manage their security. Initially focusing on vulnerability management, the company has since expanded its portfolio to include detection and response, security information and event management, cloud security, threat intelligence, application security, and security orchestration, automation, and response. Rapid7 empowers businesses with visibility and insights to make informed security decisions, create action plans, and monitor progress. The company, based in Boston, is committed to helping organizations enhance their security posture and is actively involved in the cybersecurity community.

Remedium Bio is a Boston-based gene therapy company dedicated to developing curative treatments for various debilitating conditions. The company employs a modular approach to research and development, utilizing established technologies in innovative ways to address well-understood disease mechanisms. By focusing on clinically validated molecules and targeted treatment strategies, Remedium Bio aims to create effective therapies for conditions within rheumatology, endocrinology, and neurology. Its pipeline includes promising gene therapy candidates designed to tackle a wide range of diseases, including immune and age-related disorders.

Quantivly, Inc. is a technology company based in Somerville, Massachusetts, that specializes in artificial intelligence solutions for radiology. Founded in 2019, it focuses on developing software that manages and analyzes MRI imaging workflows. The company's platform enables radiology providers to access a vendor-neutral, granular source of operational data by analyzing and harmonizing scanner information. This capability supports radiology departments and imaging centers in making data-driven decisions, improving operational efficiency, and enhancing patient-centered healthcare. By offering tools for data liquidity and analysis, Quantivly aims to increase access to medical imaging and drive advancements in research and patient care within the radiology sector.

The University of Massachusetts Amherst is a public research and land-grant university that offers undergraduate, master's, and doctoral programs. It serves as the flagship campus of the University of Massachusetts system. The university has multiple academic departments and research facilities that support a range of disciplines.

QSimulate is a Boston-based company that develops cloud-based quantitative simulation tools aimed at addressing complex challenges in the chemical and pharmaceutical industries. By harnessing the principles of quantum mechanics, QSimulate’s platform facilitates quantum molecular simulations, allowing clients to tackle industrial-scale problems more effectively. The tools offered by the company automate workflows, relieving computational scientists of routine tasks and thereby increasing productivity. This innovation enables organizations to accelerate their research and development processes, ultimately enhancing their capacity to innovate and solve critical issues in their fields.

Singularity Energy, Inc. is a company focused on developing real-time carbon tracking and decision-making solutions aimed at helping corporate customers optimize their energy usage and reduce carbon emissions. Founded in 2018 by Wenbo Shi, the company utilizes artificial intelligence to integrate real-time carbon dioxide signals from the grid into its platform. This technology enables businesses, including climate regulators and sustainability directors, to visualize and co-optimize their energy resources while balancing cost and emissions. Based in Cambridge, Massachusetts, Singularity Energy provides essential data infrastructure that supports grid decarbonization efforts, allowing organizations to meet their sustainability targets with confidence and transparency.

Belmont Scientific is a chemical and battery safety technology company that specializes in process safety and risk management. The company was founded in 2011 and is based in Lowell, Massachusetts.

RaySecur Inc., based in Cambridge, Massachusetts, develops advanced 3D package scanning and imaging devices designed to detect concealed threats, including powders, solids, liquids, and chemical, biological, radiological, and explosive materials. Founded in 2018, the company offers the MailSecur system, which utilizes innovative millimeter-wave technology to provide real-time imaging and threat detection that surpasses traditional X-ray systems. RaySecur’s portable and easy-to-use devices require minimal training for mail screening and can fit in small mailrooms without the need for secure screening areas. Their technology is capable of identifying tiny quantities of substances, making it suitable for use by Fortune 500 companies and government organizations worldwide, ensuring the safety of personnel and critical assets.

Lura Health has developed a groundbreaking non-invasive health monitoring platform that utilizes saliva as a diagnostic fluid, aiming to enhance clinical outcomes in chronic disease management. Founded in 2017 and based in Cambridge, Massachusetts, the company targets various chronic disease markets, including heart disease, chronic kidney disease, diabetes, and tooth decay. Its innovative sensors are integrated into patient-friendly orthodontic devices such as removable retainers and fixed braces. These sensors continuously measure analytes in saliva and automatically transmit data to a smartphone application, allowing users to track key diagnostic metrics related to their oral health. By enabling individuals to monitor their health in real-time, Lura Health seeks to improve personal health management and empower users to take charge of their well-being.

Dynocardia, Inc. is a biomedical device company based in Massachusetts that specializes in wireless blood pressure measurement equipment. Founded in 2018, the company has developed a wrist-wearable device called ViTrack, which allows users to accurately and continuously measure vital health parameters, including blood pressure, heart rate, heart rhythm, and respiration rate. Utilizing an innovative optomechanical sensor, Dynocardia's technology offers a non-invasive method for blood pressure measurement, rivaling the accuracy of traditional intra-arterial measurements. The company's focus is on addressing critical unmet healthcare needs, providing a mobile, user-friendly solution for monitoring cardiovascular health.

AM Batteries, founded in 2016 and headquartered in Chelmsford, Massachusetts, specializes in the manufacture of lithium-ion batteries utilizing innovative solvent-free electrode manufacturing technology. This approach aims to address the challenges associated with traditional solvent-based processes by eliminating the need for solvent recovery and electrode drying. As a result, AM Batteries' technology not only reduces energy consumption in battery production but also has the potential to enhance battery performance, enabling faster charging and lower production costs. The company's focus on dry electrode manufacturing positions it as a forward-thinking player in the battery industry, committed to improving efficiency and sustainability in battery technology.

The University of Massachusetts (UMass) Dartmouth is known for its rigorous academic programs, especially in the areas of engineering, law, marine science, and Portuguese studies.

Boston Geospatial specializes in delivering geospatial insights tailored for operators and risk managers within critical infrastructure sectors. The company has developed a comprehensive geospatial data platform that facilitates access to various satellite data providers. This platform allows users to search, compare, and analyze data in multiple ways, thereby enhancing decision-making processes and risk assessment. By offering ready-to-use insights, Boston Geospatial supports effective management and operational efficiency in vital industries.

Alloy Enterprises Inc. is a company based in Somerville, Massachusetts, that specializes in developing advanced 3D printing technologies aimed at addressing inefficiencies in conventional manufacturing processes. Founded in 2020, Alloy focuses on industrial engineering and manufacturing technology, particularly for aluminum parts. The company's innovative aluminum additive technology allows for the production of dense, low-cost parts without relying on expensive and hazardous powders. This approach helps clients overcome limitations associated with traditional manufacturing methods, fostering innovation and facilitating progress in lightweight design and emissions reduction.

Thiozen is a company based in Belmont, Massachusetts, that specializes in innovative hydrogen gas production technology aimed at reducing greenhouse gas emissions. Founded in 2020, Thiozen employs a unique chemical process that converts hydrogen sulfide into hydrogen gas. This method not only significantly lowers greenhouse gas emissions but also allows clients to bypass the carbon emissions typically associated with hydrogen production from natural gas and the high costs linked to electrolysis. By offering a low-cost and low-emission alternative, Thiozen positions itself as a key player in the transition to cleaner energy solutions.

Chibitronics specializes in the creation of circuit stickers that integrate electronics with art and craft. Founded by Jie Qi, along with collaborators Andrew Huang and Patricia Ng, the company emerged from Qi's PhD research at the MIT Media Lab. Chibitronics offers toolkits that allow users to build circuits and programs using peel-and-stick electronics, including conductive circuit stickers, coin cell batteries, and adhesive copper tape. This innovative approach enables artists, crafters, and students to explore their creativity while experiencing the functionality of lights and circuitry. By combining technology and artistic expression, Chibitronics aims to empower individuals to become creators in the field of expressive electronics.

Biko Biolabs is a research company founded in 2020 and located in Somerville, Massachusetts, that focuses on the intersection of plastic waste and regenerative agriculture. The company aims to address research and development gaps related to sustainability and self-sufficiency in traditionally marginalized communities. By providing resources to innovators, Biko Biolabs fosters the creation of new economic opportunities and trains emerging local scientists and engineers. The company emphasizes impactful research that is closely aligned with the specific needs of the communities involved, enabling tailored scientific practices and technologies that directly address fundamental community challenges.

Skyhaven Systems is a research and development firm headquartered in Steamboat Springs, Colorado, with primary laboratories in Westford, Massachusetts. Established in 2017 through the merger of Reactive Innovations, LLC, the company specializes in addressing critical needs of the U.S. Government across the Defense, Energy, Aerospace, and Environmental sectors. Skyhaven employs advanced electrochemical engineering and reaction-based chemistry to tackle complex technical challenges, working closely with agencies such as the Department of Defense, NASA, and the Environmental Protection Agency. The firm focuses on innovative chemical process technologies, including reactor design and thermal management, to develop operational prototypes and deliver research findings. As a small business, Skyhaven retains technology rights from its government-funded projects, providing the government with a royalty-free license while also enabling the firm to pursue commercialization opportunities. This strategic approach allows Skyhaven to address high-risk development areas often overlooked by larger organizations, fostering innovation through government contracts and grants. The firm actively protects its intellectual property through patents and trade secrets, positioning itself for future growth in both governmental and commercial markets.

MedChem Partners is a medicinal chemistry CRO that specializes in developing small molecule therapeutics. The company was founded in 2006 and is headquartered in Lexington, Massachusetts.

Theromics Inc. is a biotechnology company focused on developing innovative cell therapies, particularly in the field of thermal ablation for cancer treatment. Founded in 2016 and based in West Bridgewater, Massachusetts, the company has created HeatSYNC Gel, a biopolymer thermal accelerant designed to enhance the effectiveness of microwave and radiofrequency ablation procedures. This gel improves the delivery and absorption of thermal energy in soft tissue and bone, optimizing the ablation zone's shape and volume. By increasing local tissue electrical conductivity, HeatSYNC Gel helps to prevent heat loss due to blood flow, allowing for more precise targeting of tumors and protecting surrounding healthy tissue. The gel can be administered through various methods, including syringe, laparoscope, and bronchoscope, and is intended to improve the overall efficacy of thermal ablation therapies while enabling personalized treatment approaches.

Stellate DNA, founded in 2020 and based in Cambridge, Massachusetts, specializes in proprietary DNA donor technology aimed at synthesizing and producing single-strand DNA donors. The company employs a clonal synthesis platform rather than traditional chemical methods, enabling the production of customizable gene knock-in payloads. This approach ensures well-controlled production at microgram to milligram scales, assisting medical professionals in achieving minimal mutation rates and maintaining sequence uniformity. Through its innovative technology, Stellate DNA addresses the demands of the biotechnology sector while supporting advancements in genetic research and therapeutic applications.

Simpact is a Boston-based company that specializes in developing analytics and forecasting software designed to aid businesses in making informed, data-driven decisions. The software utilizes computer simulations to model target social systems, allowing clients to evaluate risks related to influencers, trends, and interventions. By doing so, Simpact enables organizations to effectively forecast the outcomes of various allocations of their limited resources, ultimately enhancing their strategic planning and decision-making processes.

Xheme is a technology company based in Newton, Massachusetts, founded in 2019. The company specializes in developing advanced blood bag technology that enhances the shelf life of blood and platelets. In addition to its focus on the healthcare sector, Xheme also creates specialty chemicals aimed at improving product quality, sustainability, and safety across various industrial applications. Its innovative products are designed to be programmable, offering multiple protective functions such as resistance to oxidation, ultraviolet light, corrosion, and microbial threats. This dual approach enables industries to preserve both the aesthetic and functional integrity of their products over time.

Heila Technologies develops a platform that connects solar arrays, batteries, and other distributed energy resources (DERs) to create self-managing microgrids. The Heila IQ Platform is a decentralized optimization system that simplifies the integration and operation of these resources, allowing for autonomous management and optimization. This technology transforms various components, such as batteries and solar arrays, into independent intelligent agents capable of self-organization and regulation. Heila Technologies serves a diverse clientele, including utility representatives, developers, energy users, and public officials. Founded in 2017 and based in Somerville, Massachusetts, the company aims to facilitate the commercialization of its platform, providing granular analysis and data-driven recommendations to enhance the resilience and efficiency of energy networks while promoting energy savings and reducing carbon emissions.

Irradiant Technologies, founded in 2020 and based in Cambridge, Massachusetts, specializes in advanced nanofabrication utilizing implosion fabrication lithography. The company focuses on developing a platform that facilitates the ultrafast three-dimensional assembly of mixed materials, such as conductors, semiconductors, dielectrics, proteins, and DNA, with nanoscale precision and gradient control. This innovative approach enables the creation of novel photonic and optical components, providing light-based alternatives for applications in telecommunications, computation, and sensing.

FluidForm Bio is a biotechnology company focused on creating living human tissue to enhance disease treatment. Utilizing its patented FRESH technology, the company specializes in 3D bioprinting, which enables the production of high-quality tissue that mimics real human tissue by integrating cells and proteins without additional materials. This innovative platform allows for the design and fabrication of complex tissue structures with embedded vasculature and multiple materials within a single print. Through collaborations with leading life science companies, FluidForm Bio's technology has been validated for various applications, paving the way for novel therapeutic programs in the healthcare sector. Founded in 2018 and headquartered in Waltham, Massachusetts, FluidForm Bio aims to provide better treatment options for patients through its transformational approach to tissue engineering.

Aliro Technologies, Inc., founded in 2019 and headquartered in Boston, Massachusetts, specializes in developing cloud-based software for quantum computing. The company's platform provides a hardware-independent toolkit that facilitates the creation of quantum algorithms and applications, catering to developers in the quantum environment. Known for its product AliroNet™, the company focuses on emulating, piloting, and deploying entanglement-based quantum networks that support various applications, including secure communications and distributed quantum sensing. Emerging from NarangLab at Harvard University, Aliro Technologies boasts a team of experts in quantum and classical networking and actively contributes to the advancement of quantum networking technologies. Its users range from utility companies and telecommunications providers to public sector organizations and researchers engaged in building scalable quantum systems. The company collaborates with industry and academic partners through initiatives like the Quantum Economic Development Consortium and the NSF Center for Quantum Networks, while also participating in several quantum networking standards groups.

SiTration, founded by Brendan Smith in 2020 and based in Cambridge, Massachusetts, specializes in the development of ultra-durable filtration membranes tailored for efficient separations in harsh environments. The company's innovative technology enhances energy efficiency in challenging industrial applications by integrating the low cost and exceptional durability of various advanced commercial membranes. This enables users to achieve resource-efficient operations even in demanding conditions, setting SiTration apart in the filtration industry.

Enable Therapeutics is a biotechnology company developing a patented drug delivery platform. The company was founded in 2020 and is headquartered in Hopedale, Massachusetts.

SilarTek, founded in 2020 and based in Leominster, Massachusetts, focuses on developing innovative solar silicon technology to enhance the affordability of solar panels. The company employs molten salt electrolysis combined with advanced molten salt compositions to produce low-cost solar-grade silicon. This technology aims to make solar energy more accessible to a broader consumer base, facilitating the adoption of renewable energy solutions.

Spero Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Cambridge, Massachusetts, dedicated to developing innovative treatments for multi-drug resistant (MDR) bacterial infections and rare diseases. Founded in 2013, the company is advancing several product candidates, including tebipenem pivoxil hydrobromide, an oral carbapenem-class antibiotic aimed at treating MDR gram-negative infections in adults. Additionally, Spero is developing SPR206, an intravenous agent for MDR gram-negative infections in hospital settings, and SPR720, an oral antibiotic targeting pulmonary non-tuberculous mycobacterial disease. The company collaborates with various partners, including Meiji Seika Pharma to support tebipenem HBr's development and the Bill & Melinda Gates Medical Research Institute for SPR720. Spero Therapeutics employs a focused approach to drug development, emphasizing novel mechanisms to address the urgent need for effective therapeutics against serious bacterial infections.

Quantivly, Inc. is a technology company based in Somerville, Massachusetts, that specializes in artificial intelligence solutions for radiology. Founded in 2019, it focuses on developing software that manages and analyzes MRI imaging workflows. The company's platform enables radiology providers to access a vendor-neutral, granular source of operational data by analyzing and harmonizing scanner information. This capability supports radiology departments and imaging centers in making data-driven decisions, improving operational efficiency, and enhancing patient-centered healthcare. By offering tools for data liquidity and analysis, Quantivly aims to increase access to medical imaging and drive advancements in research and patient care within the radiology sector.

GreenSight Agronomics, Inc., established in 2015 and headquartered in Brookline, Massachusetts, specializes in manufacturing drones tailored for turfgrass and agricultural applications. The company operates a cloud-based platform that integrates automated drone systems, advanced sensors, and data analytics to provide actionable insights for land managers. GreenSight's services include plant health monitoring, irrigation management, crop protection, and labor management, primarily serving the golf course industry with potential savings of over $1 billion annually through water reduction alone. The company aims to expand its services to other agricultural sectors, such as farms and energy infrastructure, using its advanced sensor technology and autonomous drone capabilities.

Vaxess Technologies, Inc. is a biotechnology company based in Boston, Massachusetts, founded in 2011. The company focuses on developing and commercializing innovative silk biomaterial technologies. Its key product, the MIMIX microneedle platform, facilitates the transdermal delivery of vaccines and therapeutics. This sustained release patch technology allows for a controlled release of vaccines, mimicking the natural infection process to enhance immune response and effectiveness. Vaxess's patch is engineered for stability, eliminating the need for refrigeration, which enables shipping and application in low-resource settings. In addition to its vaccine delivery systems, Vaxess is also engaged in creating novel therapies aimed at oncology care and infectious diseases, ultimately striving to improve patient outcomes with reduced treatment burdens.

Ernest Pharmaceuticals is a biotechnology company based in Hadley, Massachusetts, founded in 2016. The company specializes in developing innovative bacterial therapeutics aimed at treating cancer. Its unique approach involves programming bacteria to deliver intracellular macromolecules directly into tumor tissues. These engineered bacteria are motile, allowing them to actively penetrate and target metastatic diseases and inoperable tumors. Through these advancements, Ernest Pharmaceuticals aims to enhance treatment options for patients facing challenging cancer diagnoses.

Millimeter Wave Systems, founded in 2016 and headquartered in Amherst, Massachusetts, specializes in millimeter wave and microwave hardware solutions. The company develops a range of products, including subsystems, modules, components, and antennas, as well as advanced technologies such as cryogenic quantum-limited parametric amplifiers and latching junction ferrite circulators. These innovations are utilized in various applications, including medical scanners, sensors, automobile radars, and high data-rate communications. Millimeter Wave Systems aims to provide consistent quality in production while offering customizable solutions tailored to specific industry needs.

Thinking Robots, founded in 2010 and based in Boston, Massachusetts, specializes in software solutions for robotic tasks applicable across various robotic platforms. The company develops custom software that integrates natural language dialogue, sensors, and actuators to enhance robotic architecture. This technology enables robots to interact with humans and includes high-level planning capabilities, allowing developers to create interactive and teachable robots that can be directly instructed by users.

Leading Edge Equipment Technologies, Inc. is a manufacturer and supplier of equipment for solar panel production. Founded in 2008 and based in Wilmington, Massachusetts, the company specializes in developing kerfless, single-crystal silicon wafers designed to enhance the efficiency and reduce the costs of solar cells and panels. Their innovative floating silicon method eliminates the need for wire-sawing large silicon ingots, utilizing less energy-intensive furnaces and resulting in higher efficiency solar cells. This technology not only lowers manufacturing costs but also reduces emissions, making it an environmentally friendly option for solar panel manufacturers. Formerly known as Leading Edge Crystal Technologies, the company rebranded in May 2020 to reflect its focus on advanced equipment technologies in the renewable energy sector.

Armada Marine Robotics, based in Falmouth, Massachusetts, specializes in developing asymmetric propulsion technology. This innovation allows for enhanced marine maneuverability, offering both thrust and steering from a single motor. The company's systems enable customers to create more efficient and agile underwater vehicles.

ActivSignal, established in 2016 and based in Natick, Massachusetts, specializes in biotechnology. The company focuses on developing innovative protein profiling technologies, primarily serving the proteomics research sector. Their tools enable scientists to analyze multiple signaling pathways simultaneously, providing insights into cellular pathway activation or inhibition profiles.

Travera, LLC is a biotechnology company based in Cambridge, Massachusetts, founded in 2017. It specializes in a unique measurement technology that utilizes the Suspended Microchannel Resonator (SMR), a MEMS device capable of detecting minute changes in the weight of individual cancer cells. This technology focuses on the Mass Accumulation Rate (MAR) biomarker, which indicates how cancer cells respond to various drugs within hours of exposure. By measuring these rapid changes, Travera enables oncologists to make informed decisions about which therapies to prescribe based on the actual responses of a patient’s tumor cells. This approach aims to enhance the effectiveness of cancer treatment by distinguishing between natural cell death and drug-induced cell death, thereby improving patient outcomes.

Lura Health has developed a groundbreaking non-invasive health monitoring platform that utilizes saliva as a diagnostic fluid, aiming to enhance clinical outcomes in chronic disease management. Founded in 2017 and based in Cambridge, Massachusetts, the company targets various chronic disease markets, including heart disease, chronic kidney disease, diabetes, and tooth decay. Its innovative sensors are integrated into patient-friendly orthodontic devices such as removable retainers and fixed braces. These sensors continuously measure analytes in saliva and automatically transmit data to a smartphone application, allowing users to track key diagnostic metrics related to their oral health. By enabling individuals to monitor their health in real-time, Lura Health seeks to improve personal health management and empower users to take charge of their well-being.

Metalmark Innovations, Inc. develops advanced 3D nanostructured coatings designed to treat airborne pollutants and toxins, thereby enhancing indoor air quality. The company offers its innovative materials as coating additives for various applications, including building materials and vehicle interiors. Its technology effectively targets and breaks down harmful substances such as hydrocarbons, carbon monoxide, ozone, PM2.5, volatile organic compounds, odors, and germs in diverse transportation settings, including airplanes, ships, trains, cars, and buses. Founded in 2017 and based in Boston, Massachusetts, Metalmark Innovations aims to address the pressing challenges of air pollution and climate change through its cutting-edge air cleaning solutions. The company was previously known as Aircrew Technologies, Inc. before rebranding in January 2019.

Mizar Imaging, founded in 2017 and based in Woods Hole, Massachusetts, specializes in developing modular light sheet illumination systems aimed at enhancing research and microscopy experiences. The company's innovative system is designed for high-resolution imaging and can be integrated with most modern inverted microscopes. It is compatible with high numerical aperture objectives, which helps reduce photobleaching, thereby facilitating longer imaging sessions of living cells.

Infinite Cooling Inc. specializes in water recovery systems designed for power plants and other industrial facilities. Founded in 2017 and based in Massachusetts, the company focuses on mitigating water scarcity by employing innovative technology that utilizes high-voltage electric fields to capture and recycle water evaporating from cooling towers. This approach allows power plants, data centers, and factories to significantly reduce water consumption and treatment costs, thereby promoting more sustainable operations. Through its efforts in wastewater management and recycling, Infinite Cooling aims to address environmental challenges related to water waste in industrial processes.

VeraMorph is a pharmaceutical company established in 2017 and located in Mansfield, Massachusetts. The company specializes in developing an innovative oral drug delivery technology centered around proprietary oral hydrogel tablets. This technology is designed to enhance drug stability, expedite dissolution rates, and maintain prolonged high saturation levels, allowing for higher drug loading compared to existing formulations. By providing contract manufacturing and formulation services, VeraMorph aims to assist pharmaceutical companies in improving the performance of their products while reducing both costs and the time required to bring new drugs to market.

Ichosia Biotechnology, founded in 2019 and based in Worcester, Massachusetts, focuses on the development of derived red blood cells by leveraging natural genetic processes. The company has created a platform that genetically engineers human stem cells to produce red blood cells, aiming to support healthcare providers and patients in need. This innovative approach enables the provision of blood on demand for patients at risk, addressing critical shortages and improving patient care in medical settings.

Alloy Enterprises Inc. is a company based in Somerville, Massachusetts, that specializes in developing advanced 3D printing technologies aimed at addressing inefficiencies in conventional manufacturing processes. Founded in 2020, Alloy focuses on industrial engineering and manufacturing technology, particularly for aluminum parts. The company's innovative aluminum additive technology allows for the production of dense, low-cost parts without relying on expensive and hazardous powders. This approach helps clients overcome limitations associated with traditional manufacturing methods, fostering innovation and facilitating progress in lightweight design and emissions reduction.

InThePendant is a technological platform founded in 2019 and headquartered in Lexington, Massachusetts. The company focuses on delivering meaningful insights through its innovative solutions. By leveraging advanced technology, InThePendant aims to enhance understanding and decision-making for its users.

GelSight, Inc. specializes in advanced sensor technology solutions for precise surface measurements. The company has developed the GelSight benchtop scanner, which captures the surface geometry of various materials and accurately measures rigid objects across a wide range of scales. Their innovative technology allows for detailed three-dimensional visualization and measurement, revealing features that are not discernible to the naked eye, and providing dimensional accuracy to single-digit microns. GelSight's products are utilized in diverse sectors, including aerospace, electronics, and forensics, as well as in academic and research environments. Founded in 2011 and headquartered in Waltham, Massachusetts, GelSight continues to enhance its offerings while addressing the evolving surface measurement needs of its clients.

Boston Materials, Inc. is a manufacturer of advanced composite materials, specializing in 3D reinforced carbon fiber pre-pregs. Founded in 2016 and based in Bedford, Massachusetts, the company utilizes patented Z-axis Fiber technology, which incorporates vertically aligned carbon fibers to enhance energy transfer properties. Its product line includes Carbon Supercomposite, a magnetically assembled carbon fiber pre-preg, which finds applications across various sectors such as aerospace, automotive, marine, wind energy, and sports equipment. Boston Materials' advanced materials aim to improve thermal, electrical, and mechanical properties, offering a roll-to-roll manufacturing process with in-line quality control and an annual production capacity of one million square meters. These innovations enable industries like semiconductors and electrified vehicles to achieve greater efficiency, reliability, and weight reduction while addressing critical challenges in durability and performance.

Bitome is a Boston-based company specializing in connected medical devices, focusing on noninvasive hydration monitoring technology. Established two years ago, Bitome's first product is designed to monitor hydration status, with significant applications in fields such as dialysis, diabetes management, sports performance, and maternal/fetal health. One of its primary uses is in assessing volume status in patients with congestive heart failure (CHF), a critical but challenging biometric to measure that is closely linked to patient outcomes. By enhancing hydration monitoring, Bitome aims to revolutionize CHF management in a manner similar to how glucose monitoring transformed diabetes care.

Root AI, Inc. is a company that specializes in manufacturing artificial intelligence robots designed for indoor farming. Founded in 2018 and based in Woburn, Massachusetts, the company has developed Virgo 1, an autonomous robot specifically engineered for harvesting tomatoes. This robot excels in picking tomatoes without causing bruising and can assess ripeness with greater accuracy than human laborers. Root AI aims to enhance the efficiency of indoor agriculture by integrating advanced vision systems and AI technology, enabling growers to produce high-quality, chemical-free crops while maximizing productivity in smart farm environments.

Quisigamond Community College, located in Worcester, MA, serves over 13,000 students and offers more than 70 associate degree and certificate programs. In addition to the traditional student academic program, Quisigamond offers online classes specifically geared toward working students or professionals who want to enhance their skills or build new ones. Those classes include Business Administration, Fire Science, Criminal Justice, Computer Science and Hospitality Management. Certificates are available in business administration/insurance or medical office options, Hotel and Restaurant Management, Early Childhood Education, and Law Enforcement. Various healthcare certificates are also offered including Surgery Technology, basic Paramedic and Dental Assisting. Associate Degrees are offered in Deaf Studies, Biomedical Engineering, Electromechanical Technology, Telecommunications Technology and Energy Utility. Quisigamond has developed outstanding relationships with potential employers in the central Massachusetts area including Intel, Verizon, Kennedy Diecasting, UPS and Ken-Weld and sponsors regular collaborations for workforce training. The Children’s School is available for enrolled students and members of the community with children between the ages of 2 to 5 years and also operates as a training center for Early Childhood Education students . The Division of Continuing Education hosts non-credit courses, workshops and seminars that are widely attended by the community and students.

JuliaHub is a platform that facilitates modeling, simulation, and the development of user-built applications, primarily targeting scientists, engineers, and innovators. Established in 2015 by Viral Shah in Cambridge, Massachusetts, JuliaHub provides high-performance computing capabilities that enable users to bring their innovative ideas to fruition at any scale. The platform supports the open-source Julia programming language, which is designed to simplify programming tasks related to data science, machine learning, and scientific computing. This includes applications in research, backtesting, trading, and contract modeling. With features that emphasize ease of use and an intuitive syntax, JuliaHub enhances the user experience while maintaining robust performance for complex data analysis and computations.

Singularity Energy, Inc. is a company focused on developing real-time carbon tracking and decision-making solutions aimed at helping corporate customers optimize their energy usage and reduce carbon emissions. Founded in 2018 by Wenbo Shi, the company utilizes artificial intelligence to integrate real-time carbon dioxide signals from the grid into its platform. This technology enables businesses, including climate regulators and sustainability directors, to visualize and co-optimize their energy resources while balancing cost and emissions. Based in Cambridge, Massachusetts, Singularity Energy provides essential data infrastructure that supports grid decarbonization efforts, allowing organizations to meet their sustainability targets with confidence and transparency.

Belmont Scientific is a chemical and battery safety technology company that specializes in process safety and risk management. The company was founded in 2011 and is based in Lowell, Massachusetts.

RaySecur Inc., based in Cambridge, Massachusetts, develops advanced 3D package scanning and imaging devices designed to detect concealed threats, including powders, solids, liquids, and chemical, biological, radiological, and explosive materials. Founded in 2018, the company offers the MailSecur system, which utilizes innovative millimeter-wave technology to provide real-time imaging and threat detection that surpasses traditional X-ray systems. RaySecur’s portable and easy-to-use devices require minimal training for mail screening and can fit in small mailrooms without the need for secure screening areas. Their technology is capable of identifying tiny quantities of substances, making it suitable for use by Fortune 500 companies and government organizations worldwide, ensuring the safety of personnel and critical assets.

Ras Labs, LLC, founded in 2003 and based in Quincy, Massachusetts, specializes in the development and production of Synthetic Muscle, a polymer-based material that mimics natural movement by expanding and contracting in response to electrical impulses. This innovative technology is designed to enhance the interaction between mechanical devices and humans, with a focus on applications in prosthetics, rehabilitative robotics, and protective devices. In addition to Synthetic Muscle, Ras Labs creates robotic arm products that utilize material science advancements and data engineering to improve automation processes. These products include tactile sensors for robotic fingers, enabling gentle gripping of fragile objects and providing touch detection and location feedback, thus facilitating adaptable responses in automated gripping systems.

The University of Massachusetts (UMass) Dartmouth is known for its rigorous academic programs, especially in the areas of engineering, law, marine science, and Portuguese studies.

DeepHealth, Inc. is a radiology artificial intelligence and machine learning company based in Cambridge, Massachusetts, founded in 2015. The company specializes in developing solutions for the medical interpretation of mammography exams, leveraging data science and imaging analysis to support radiologists in their diagnostic processes. By utilizing machine learning, DeepHealth distills extensive insights from medical experts into software designed to enhance the accuracy and reliability of radiological assessments. The company's mission is to improve patient care by providing trustworthy products that are grounded in rigorous scientific research and integrated into clinical practice.

Boston Children's Museum, founded in 1913 by the Science Teachers' Bureau, is the second oldest children's museum in the world and a significant educational institution in Boston, Massachusetts. As an independent non-profit foundation, it is dedicated to promoting the healthy development of all children, enabling them to reach their potential and contribute to society. The museum provides engaging, hands-on experiences that foster joyful discovery, instill an appreciation for the world, and develop foundational skills. For over a century, it has served as a vital resource for both children and educators, facilitating the exchange of ideas and materials that enhance the teaching of science and learning. The foundation's operations are overseen by a Board of Trustees, ensuring its mission remains aligned with its commitment to childhood education and development.

Sober Grid, Inc. is a digital health company that operates a sober social network aimed at supporting individuals in recovery from substance use disorders. Incorporated in 2015 and based in Boston, Massachusetts, the company has developed a mobile application available on both iOS and Android platforms. The app allows users to connect with others who are also navigating sobriety, fostering a community where they can share experiences and challenges. Sober Grid's platform is utilized in over 170 countries and has been accessed more than 20 million times. It integrates features such as GPS locator interfaces, direct messaging, and educational resources, while also offering certified coaching services available 24/7. The app employs a unique community-based approach to chronic disease management, utilizing predictive analytics to anticipate relapse risks and provide timely interventions. Sober Grid's commitment to improving health outcomes is supported by research collaborations with esteemed institutions like Harvard Medical School and the University of Pennsylvania, demonstrating its effectiveness in reducing relapse rates among users.

Infinite Cooling Inc. specializes in water recovery systems designed for power plants and other industrial facilities. Founded in 2017 and based in Massachusetts, the company focuses on mitigating water scarcity by employing innovative technology that utilizes high-voltage electric fields to capture and recycle water evaporating from cooling towers. This approach allows power plants, data centers, and factories to significantly reduce water consumption and treatment costs, thereby promoting more sustainable operations. Through its efforts in wastewater management and recycling, Infinite Cooling aims to address environmental challenges related to water waste in industrial processes.

Elephant Stem develops a video game platform to assist students in learning statistics. The company is based in Cambridge, Massachusetts.

Heila Technologies develops a platform that connects solar arrays, batteries, and other distributed energy resources (DERs) to create self-managing microgrids. The Heila IQ Platform is a decentralized optimization system that simplifies the integration and operation of these resources, allowing for autonomous management and optimization. This technology transforms various components, such as batteries and solar arrays, into independent intelligent agents capable of self-organization and regulation. Heila Technologies serves a diverse clientele, including utility representatives, developers, energy users, and public officials. Founded in 2017 and based in Somerville, Massachusetts, the company aims to facilitate the commercialization of its platform, providing granular analysis and data-driven recommendations to enhance the resilience and efficiency of energy networks while promoting energy savings and reducing carbon emissions.

Ecto specializes in technology that merges data and biology to enhance the efficiency and sustainability of the aquaculture industry. By collaborating with farmers, Ecto streamlines production and health management through advanced molecular tools and digital technologies. Their innovative solutions have helped farmers generate over 51 million additional healthy servings of protein. The company operates offices in Boston, Atlanta, and Stavanger, Norway, serving a global customer base. Founded in 2013 at Harvard Innovation Labs by Dmitry Kozachenok and James Webb, Ecto has secured competitive research grants from prominent organizations such as the US National Science Foundation, the US Department of Agriculture, and Innovation Norway. Their farm management platform simplifies data recording and offers real-time insights, enabling farmers to monitor operations effectively, detect diseases, and manage production cycles in challenging environments.

AmberWave, Inc. is a research and development company specializing in photovoltaic technology solutions for commercial buildings, as well as semiconductor manufacturing technologies. Founded in 1998, the company has developed a range of advanced materials and technologies, including Strained Silicon, which enhances microchip performance while reducing power consumption, and Aspect Ratio Trapping, used for silicon-based photonics and photovoltaic applications. AmberWave aims to provide high-value products for underrepresented markets and new applications, focusing on substrate engineering for integrated circuits, semiconductor lighting, and photovoltaics. The company is headquartered in Salem, New Hampshire, and was previously known as AmberWave Systems Corporation before changing its name in 2010.

Boston Microtechnology is a semiconductor company that specializes in the development of CMOS-integrated isolated AC/DC conversion. The company was founded in 2014 and is based in Burlington, Massachusetts.

University of Massachusetts Lowell is a high-ranking university, with several nationally recognized academic departments. Located about 30 minutes from Boston in Lowell, Massachusetts, UMass Lowell offers more than 100 degree programs at the undergraduate and graduate levels. UMass Lowell has several nationally recognized, research-oriented programs, including science and engineering. These programs undertake groundbreaking research and also provide exceptional work opportunities for its students and graduates. Other programs at UMass Lowell include liberal and fine arts, humanities, health-related programs, teacher education and social sciences. UMass Lowell also offers a range of internship opportunities for students who wish to gain experience in their field of study. Student life options at UMass Lowell include more than 100 diverse student organizations, leadership programs and community service opportunities. Lowell’s admissions policies are moderately competitive. Financial aid is available to eligible students through loans, academic scholarships and other sources to help cover tuition.

Metalmark Innovations, Inc. develops advanced 3D nanostructured coatings designed to treat airborne pollutants and toxins, thereby enhancing indoor air quality. The company offers its innovative materials as coating additives for various applications, including building materials and vehicle interiors. Its technology effectively targets and breaks down harmful substances such as hydrocarbons, carbon monoxide, ozone, PM2.5, volatile organic compounds, odors, and germs in diverse transportation settings, including airplanes, ships, trains, cars, and buses. Founded in 2017 and based in Boston, Massachusetts, Metalmark Innovations aims to address the pressing challenges of air pollution and climate change through its cutting-edge air cleaning solutions. The company was previously known as Aircrew Technologies, Inc. before rebranding in January 2019.

Travera, LLC is a biotechnology company based in Cambridge, Massachusetts, founded in 2017. It specializes in a unique measurement technology that utilizes the Suspended Microchannel Resonator (SMR), a MEMS device capable of detecting minute changes in the weight of individual cancer cells. This technology focuses on the Mass Accumulation Rate (MAR) biomarker, which indicates how cancer cells respond to various drugs within hours of exposure. By measuring these rapid changes, Travera enables oncologists to make informed decisions about which therapies to prescribe based on the actual responses of a patient’s tumor cells. This approach aims to enhance the effectiveness of cancer treatment by distinguishing between natural cell death and drug-induced cell death, thereby improving patient outcomes.

ActivSignal, established in 2016 and based in Natick, Massachusetts, specializes in biotechnology. The company focuses on developing innovative protein profiling technologies, primarily serving the proteomics research sector. Their tools enable scientists to analyze multiple signaling pathways simultaneously, providing insights into cellular pathway activation or inhibition profiles.

Helios Applied Science develops ultra-portable innovations for first-response rescue and humanitarian relief. The company is based in Hyde Park, Massachusetts.

3Derm Systems, Inc. is a Boston-based company that specializes in 3D dermatology solutions. Founded in 2011, it has developed a handheld skin imager along with cloud-based software that enables users to capture, store, and transmit high-resolution 3D images of the skin to dermatologists. This innovative system allows non-dermatologists to take clinical-quality images remotely, facilitating efficient monitoring of skin conditions, particularly for patients at risk of skin cancer. By enabling images to be reviewed at medical kiosks and other referral sites, 3Derm helps dermatologists manage high patient volumes while reserving in-office visits for those requiring immediate attention. The company's approach aims to reduce healthcare costs, decrease wait times, and enhance access to dermatological care, allowing patients to monitor their skin from home instead of making frequent, often inconvenient, clinic appointments. 3Derm Systems operates as a subsidiary of Digital Diagnostics, Inc. as of August 2020.

Millimeter Wave Systems, founded in 2016 and headquartered in Amherst, Massachusetts, specializes in millimeter wave and microwave hardware solutions. The company develops a range of products, including subsystems, modules, components, and antennas, as well as advanced technologies such as cryogenic quantum-limited parametric amplifiers and latching junction ferrite circulators. These innovations are utilized in various applications, including medical scanners, sensors, automobile radars, and high data-rate communications. Millimeter Wave Systems aims to provide consistent quality in production while offering customizable solutions tailored to specific industry needs.

Gel4Med LLC is a Boston-based medical technology company established in 2015, specializing in the development of innovative biomaterials for tissue treatment and regeneration. The company focuses on creating an antimicrobial tissue-scaffolding matrix designed to eliminate antibiotic-resistant bacteria while promoting tissue regeneration. By utilizing bioinspired and engineered materials, Gel4Med aims to address significant healthcare challenges, particularly in wound care. Their leading technology employs a self-assembling peptide mechanism that acts as both an antibacterial barrier and a promoter of tissue regeneration, thus enhancing patient outcomes and preventing infections during surgical procedures.

Root AI, Inc. is a company that specializes in manufacturing artificial intelligence robots designed for indoor farming. Founded in 2018 and based in Woburn, Massachusetts, the company has developed Virgo 1, an autonomous robot specifically engineered for harvesting tomatoes. This robot excels in picking tomatoes without causing bruising and can assess ripeness with greater accuracy than human laborers. Root AI aims to enhance the efficiency of indoor agriculture by integrating advanced vision systems and AI technology, enabling growers to produce high-quality, chemical-free crops while maximizing productivity in smart farm environments.

Vaxess Technologies, Inc. is a biotechnology company based in Boston, Massachusetts, founded in 2011. The company focuses on developing and commercializing innovative silk biomaterial technologies. Its key product, the MIMIX microneedle platform, facilitates the transdermal delivery of vaccines and therapeutics. This sustained release patch technology allows for a controlled release of vaccines, mimicking the natural infection process to enhance immune response and effectiveness. Vaxess's patch is engineered for stability, eliminating the need for refrigeration, which enables shipping and application in low-resource settings. In addition to its vaccine delivery systems, Vaxess is also engaged in creating novel therapies aimed at oncology care and infectious diseases, ultimately striving to improve patient outcomes with reduced treatment burdens.

NanoView Biosciences is a biotechnology company that specializes in the development of technologies for the characterization of extracellular vesicles, particularly exosomes. Founded in 2015 and based in Boston, Massachusetts, the company utilizes its proprietary ExoView technology to provide high-throughput and cost-effective analysis solutions for life science researchers. NanoView's products, which include the ExoView R100 and ExoView tetraspanin, enable precise detection and multiparametric characterization of exosomes from complex biological samples such as blood, serum, plasma, and urine. In addition to its core products, the company offers custom assays, sample services, and a support platform to aid researchers in understanding the biological roles of exosomes and utilizing them as biomarkers for disease diagnosis, treatment, and monitoring.

Embr Labs Inc. is a company based in Somerville, Massachusetts, that specializes in developing thermal comfort devices aimed at enhancing human well-being. Founded in 2014 and originally known as Wristify Inc., Embr Labs has created innovative technology that uses temperature to influence the autonomic nervous system, helping users manage conditions such as hot flashes, sleep disturbances, and anxiety. The company's wearable devices, combined with a mobile app and cloud infrastructure, provide a unique platform for thermal stimulation and digital interventions, allowing users to track and manage their symptoms effectively. With tens of thousands of customers across 170 countries, Embr Labs has recorded over 100 million minutes of thermal interventions. The technology originated from the founders' work as engineering students at MIT and has received significant backing from investors and over $2.5 million in grants from various organizations.

Via Separations, Inc. is focused on developing innovative membrane-based products for industrial liquid separation in challenging environments. Founded in 2016 and based in Somerville, Massachusetts, the company aims to address the significant energy waste in the chemical separation process, which accounts for 12% of U.S. energy consumption. By employing its advanced membrane technology, Via Separations can reduce energy use by up to 90% and enhance product output. Their highly selective and robust membrane filters replace traditional heat-based separation methods, contributing to industrial decarbonization efforts. The company is currently conducting pilot trials in pulp and paper facilities, with the goal of eliminating 100 million metric tons of CO2 emissions by 2050. Originating from MIT's Department of Material Science & Engineering, Via Separations has successfully scaled its technology and demonstrated working prototypes at a commercial level.

Elektrofi is a preclinical-stage company based in Boston, Massachusetts, focused on advancing drug delivery methods to enhance patient experiences. Established in 2016, the company has developed a formulation system capable of processing a diverse array of therapeutic molecules, including large and complex proteins such as monoclonal antibodies, bispecifics, and fusion proteins. Its innovative technology aims to improve subcutaneous administration, allowing drug manufacturers to create breakthrough therapies that empower patients with more control over how they receive essential medications.

The University of Massachusetts Amherst is a public research and land-grant university that offers undergraduate, master's, and doctoral programs. It serves as the flagship campus of the University of Massachusetts system. The university has multiple academic departments and research facilities that support a range of disciplines.

KnipBio, Inc. is a biotechnology company based in Lowell, Massachusetts, established in 2013. It focuses on developing sustainable and responsible feed solutions for the aquaculture industry, primarily through its innovative product, KnipBio Meal (KBM). This product serves as a protein-rich replacement for traditional fishmeal, combining the benefits of high-quality protein and carotenoids in a single, effective formulation. KnipBio employs naturally occurring microbe strains that convert abundant and low-cost feedstocks, such as ethanol and methanol, into nutritious single-cell protein. By addressing the challenges of animal nutrition, KnipBio aims to provide livestock owners with affordable and efficient feed alternatives, contributing to the evolution of sustainable aquaculture practices.

Leading Edge Equipment Technologies, Inc. is a manufacturer and supplier of equipment for solar panel production. Founded in 2008 and based in Wilmington, Massachusetts, the company specializes in developing kerfless, single-crystal silicon wafers designed to enhance the efficiency and reduce the costs of solar cells and panels. Their innovative floating silicon method eliminates the need for wire-sawing large silicon ingots, utilizing less energy-intensive furnaces and resulting in higher efficiency solar cells. This technology not only lowers manufacturing costs but also reduces emissions, making it an environmentally friendly option for solar panel manufacturers. Formerly known as Leading Edge Crystal Technologies, the company rebranded in May 2020 to reflect its focus on advanced equipment technologies in the renewable energy sector.

AI Strike provides big data and AI technology solutions and decision support systems that improve the bottom line of clients. The company's headquarters are in Shrewsbury, Massachusetts.

Realtime Robotics, Inc. is focused on developing advanced motion planning and control processors that enable robots and autonomous vehicles to react instantaneously to their surroundings. Founded in 2016 and based in Boston, Massachusetts, the company offers a collision-free motion planning platform that allows for safe operation of single or multiple robots in unstructured environments. Their specialized RapidPlan processor generates safe motion plans in microseconds, effectively eliminating the trade-off between speed and safety in automation. This innovative technology accommodates real-time changes in dynamic environments, enabling robots to navigate around both known static objects and other moving entities while performing various tasks. By addressing the limitations of traditional automation, Realtime Robotics is broadening the applications of robotics across industries and facilitating the adoption of autonomous vehicles.

Articulate Biosciences is a preclinical stage medical device company that specializes in the development of injectable viscoelastic gels aimed at treating arthritis and other soft tissue diseases. Founded in 2016 as a spin-out from Boston University, the company focuses on creating gels that utilize tissue-protecting and function-restoring biomedical polymers. These innovative gels are designed to alleviate chronic joint pain, providing relief and restoring mobility for patients suffering from osteoarthritis.

Boston Materials, Inc. is a manufacturer of advanced composite materials, specializing in 3D reinforced carbon fiber pre-pregs. Founded in 2016 and based in Bedford, Massachusetts, the company utilizes patented Z-axis Fiber technology, which incorporates vertically aligned carbon fibers to enhance energy transfer properties. Its product line includes Carbon Supercomposite, a magnetically assembled carbon fiber pre-preg, which finds applications across various sectors such as aerospace, automotive, marine, wind energy, and sports equipment. Boston Materials' advanced materials aim to improve thermal, electrical, and mechanical properties, offering a roll-to-roll manufacturing process with in-line quality control and an annual production capacity of one million square meters. These innovations enable industries like semiconductors and electrified vehicles to achieve greater efficiency, reliability, and weight reduction while addressing critical challenges in durability and performance.

Ernest Pharmaceuticals is a biotechnology company based in Hadley, Massachusetts, founded in 2016. The company specializes in developing innovative bacterial therapeutics aimed at treating cancer. Its unique approach involves programming bacteria to deliver intracellular macromolecules directly into tumor tissues. These engineered bacteria are motile, allowing them to actively penetrate and target metastatic diseases and inoperable tumors. Through these advancements, Ernest Pharmaceuticals aims to enhance treatment options for patients facing challenging cancer diagnoses.

KnipBio, Inc. is a biotechnology company based in Lowell, Massachusetts, established in 2013. It focuses on developing sustainable and responsible feed solutions for the aquaculture industry, primarily through its innovative product, KnipBio Meal (KBM). This product serves as a protein-rich replacement for traditional fishmeal, combining the benefits of high-quality protein and carotenoids in a single, effective formulation. KnipBio employs naturally occurring microbe strains that convert abundant and low-cost feedstocks, such as ethanol and methanol, into nutritious single-cell protein. By addressing the challenges of animal nutrition, KnipBio aims to provide livestock owners with affordable and efficient feed alternatives, contributing to the evolution of sustainable aquaculture practices.

Anfiro, Inc. is a water technology start-up based in Cambridge, Massachusetts, founded in 2014. The company specializes in developing advanced reverse osmosis polymer membranes that are both chlorine resistant and exhibit high permeability. By utilizing self-assembling polymers, Anfiro's membranes significantly outperform traditional technologies, leading to reduced costs for desalinating and purifying water. This innovative approach not only enhances efficiency in water treatment processes but also aims to address global freshwater scarcity by making clean and affordable water more accessible. Through its cutting-edge membrane technology, Anfiro seeks to contribute to sustainable water solutions for a better future.

GelSight, Inc. specializes in advanced sensor technology solutions for precise surface measurements. The company has developed the GelSight benchtop scanner, which captures the surface geometry of various materials and accurately measures rigid objects across a wide range of scales. Their innovative technology allows for detailed three-dimensional visualization and measurement, revealing features that are not discernible to the naked eye, and providing dimensional accuracy to single-digit microns. GelSight's products are utilized in diverse sectors, including aerospace, electronics, and forensics, as well as in academic and research environments. Founded in 2011 and headquartered in Waltham, Massachusetts, GelSight continues to enhance its offerings while addressing the evolving surface measurement needs of its clients.

Neurable Inc. is a neurotechnology company based in Cambridge, Massachusetts, founded in 2016. The company focuses on developing artificial intelligence software that translates brain activity into actionable insights, allowing users to control software and devices solely with their thoughts. Neurable's technology facilitates various applications, including gaming, operating toys, and driving vehicles, as well as enhancing experiences in virtual and augmented reality. By leveraging patented signal processing methods and a multidisciplinary approach that combines neuroscience, biology, statistics, and machine learning, Neurable aims to create high-performance brain-computer interfaces that are accessible and user-friendly.

QSM Diagnostics, Inc. is a Boston-based company founded in 2014 as a spin-off from the Goluch Group at Northeastern University. The company specializes in the development and manufacture of point-of-care diagnostics for the rapid identification of bacterial infections, particularly focusing on ear infections caused by Pseudomonas aeruginosa in dogs. QSM Diagnostics offers testing kits that utilize single-use disposable sensor technology to detect target molecules at the wound site. This innovation aids veterinarians and physicians in enhancing their diagnostic accuracy and treatment plans, ultimately improving animal care. With decades of experience in medical device development, QSM Diagnostics is committed to advancing veterinary diagnostics through its electrochemical sensors and medical devices.