National Science Foundation

Harpe Bioherbicide Solutions is a Raleigh-based company that provides sustainable weed-management solutions for organic and industrial agriculture. Harpe Bio's technologies deliver natural crop protection by utilizing a variety of plant extracts. The plant extracts serve as a platform that may be tailored to various weed management circumstances. Harpe's herbicide platform can be used alone or in conjunction with any currently marketed herbicide. Harpe's new modes and areas of action will improve synthetic herbicide efficacy, including the reduction of resistant weed populations.

The University of North Carolina Wilmington, the state's coastal university, is dedicated to the integration of teaching and mentoring with research and service. University of North Carolina Wilmington, commitment to student engagement, creative inquiry, critical thinking, thoughtful expression and responsible citizenship is expressed in our baccalaureate and master's programs, as well as doctoral programs in areas of expertise that serve state needs. Our culture reflects our values of diversity and globalization, ethics and integrity, and excellence and innovation.

North Carolina A&T State University is so many things to so many people, both in our state and around the country. North Carolina A&T State University is an HBCU. We are a top-flight research university, the largest historically black university (HBCU) in the country, the #1 producer of degrees awarded to African Americans in North Carolina and nationally recognized or our excellence in science, technology, mathematics and engineering (STEM) education. We are a diverse community, bound by intense pride and tradition, with fiercely loyal alumni who hold positions of importance and influence in companies and government agencies across the state, the country and the world. We are achievers, driven by a curious, limitless, fearless spirit that fuels discovery and innovation, resulting in 41 patents issued based on our research, as well as numerous spin-off and start-up companies. We are inclusive and welcoming, with students from many backgrounds and cultures, every part of our state, our nation and countries around the globe. We are passionate, driven by a desire to do more, be more and make more of a difference. Since we opened our doors in 1892, we have focused on giving every student the hands-on opportunities, core knowledge and global perspective that will lead them to make real and lasting change in their lives and the lives of others. At N.C. A&T, we have so much to be proud of, and you can learn more about those "Points of Pride" here. You can also use the links below to learn more about what makes N.C. A&T unique, from our leadership and history to our many rankings and recognitions.

The University of North Carolina at Greensboro, also known as UNCG and UNC Greensboro, is a public coeducational and research university in Greensboro in North Carolina in the United States of America, and it is a constituent institution of the system of the University of North Carolina. However, the University of North Carolina at Greensboro is a stand-alone university and awards its own degrees like all members of the system of the University of North Carolina . The Southern Association of Colleges and Schools Commission on Colleges accredits the University of North Carolina at Greensboro to award baccalaureate, masters, specialist, and doctoral degrees.

Ecoclosure, founded in 2019 and based in Charlotte, North Carolina, specializes in regenerable building enclosures designed for commercial, industrial, and residential applications. The company focuses on developing technology that aims to improve indoor air quality while reducing energy consumption in buildings. Its innovative enclosures are equipped with monitoring and automation features, allowing for customized solutions tailored to various building programs, climate zones, and orientations. By prioritizing the creation of healthy indoor environments, Ecoclosure enhances occupant well-being and revitalizes indoor air quality.

ColoWrap, LLC is a medical device company based in Durham, North Carolina, focused on enhancing the colonoscopy experience. Founded in 2012, the company has developed a non-invasive device designed to prevent looping in the colon during procedures. This device applies sustained, adjustable pressure to the lower abdomen, specifically targeting the sigmoid and transverse colon, which reduces the need for manual pressure and frequent patient repositioning. Made from latex-free materials similar to those used in high-performance wetsuits, the device aims to improve patient comfort while allowing medical practitioners to perform colonoscopies with minimal invasion.

Minerva Lithium, founded in 2020 in Greensboro, North Carolina, specializes in developing advanced extraction techniques for critical minerals, particularly lithium. The company focuses on direct lithium extraction technology designed to enhance the recovery of lithium while also recovering usable water. Utilizing a proprietary nano mosaic membrane filter system, Minerva Lithium enables various sectors, including renewable energy, automotive, and technology, to extract high-grade pure minerals from non-traditional water resources. Its innovative approach aims to accelerate the development of clean energy technologies and support the growing lithium market.

North Carolina Central University (NCCU), established in 1910, is a historically black college located in Durham, North Carolina. It has built a strong reputation for its commitment to academic excellence, research, and cultural awareness. NCCU offers over 100 programs across nearly 30 academic departments, providing both undergraduate and graduate degrees. Notable offerings include unique programs such as a master’s degree in Jazz Studies and a bachelor’s degree in Apparel Design, alongside joint graduate programs in law and business. The university actively promotes diversity, welcoming students of all races and ethnicities, and provides various financial aid options, including institutional scholarships and need-based government programs. With a focus on preparing students for success in a global marketplace, NCCU continues to play a vital role in higher education and community development.

Kaleido, Inc. is a developer of a cloud-based blockchain platform that simplifies the creation and management of enterprise private blockchain networks. Based in Raleigh, North Carolina, the company offers a versatile platform that supports various protocols, including Ethereum, Polygon Edge, and Hyperledger, allowing organizations to build multi-region and multi-cloud blockchain networks. Kaleido's services include features such as token transfer, identity management, document storage, and integrated analytics, all designed to meet the rigorous demands of regulated industries. The platform ensures high availability and disaster recovery, achieving 99.99% uptime over the past four years, and is certified for security and compliance. Kaleido serves a diverse clientele, ranging from web3 startups to large enterprises, facilitating the adoption of digital asset technologies and the digitization of critical business processes across sectors such as finance, healthcare, insurance, and supply chains.

Gradient Medical, founded in 2020 and based in Raleigh, North Carolina, specializes in developing innovative interventional oncology services, specifically focused on ACE therapy. This therapy utilizes electrical pulses designed to target cancer cells and disrupt essential biological functions. By incorporating real-time sensing technology, Gradient Medical provides clinicians with enhanced control over the treatment area, which optimizes therapeutic effectiveness and reduces treatment durations. This approach enables healthcare professionals to effectively treat large, inoperable tumors located near vital structures, addressing a critical need in cancer care.

Novo Aero Technology, Inc. specializes in the development of Vertical Take-off and Landing (VTOL) aircraft. Founded in 2018 and based in Raleigh, North Carolina, the company utilizes an innovative lift-generating mechanism that incorporates ducted propellers positioned within the central fuselage. This design approach allows for a more compact powertrain with fewer moving parts compared to traditional helicopters, resulting in improved fuel efficiency. By enhancing the capabilities of VTOL aircraft, Novo Aero Technology aims to provide significant advantages to helicopter and business jet manufacturers over conventional aircraft designs.

BioAesthetics LLC, founded in 2015 as a spin-out from Tulane University, is focused on developing innovative reconstruction options for breast cancer patients following mastectomies. The company specializes in a tissue-engineered nipple-areolar complex (NAC) that serves as an acellular graft to be used by plastic and reconstructive surgeons during the breast reconstruction phase. This product allows the patient's own cells to integrate with the graft, facilitating the regeneration of a natural nipple and areola. Currently in the pre-clinical phase, this patent-pending technology aims to provide a more effective and aesthetically pleasing solution for patients who have experienced incomplete or removed NACs due to illness, surgery, or congenital conditions. BioAesthetics is headquartered in Research Triangle Park, North Carolina.

Minerva Lithium, founded in 2020 in Greensboro, North Carolina, specializes in developing advanced extraction techniques for critical minerals, particularly lithium. The company focuses on direct lithium extraction technology designed to enhance the recovery of lithium while also recovering usable water. Utilizing a proprietary nano mosaic membrane filter system, Minerva Lithium enables various sectors, including renewable energy, automotive, and technology, to extract high-grade pure minerals from non-traditional water resources. Its innovative approach aims to accelerate the development of clean energy technologies and support the growing lithium market.

Inanovate Inc. specializes in developing protein screening and analysis products for the life sciences sector. The company offers the Bio-ID platform, a protein screening biochip that provides real-time, sensitive kinetic data on multiple protein interactions. This technology is applicable in various areas, including protein research, drug development, quality control, biomarker profiling, validation, and clinical diagnostics. Inanovate also provides biomarker alliance programs, i-Slide nano-particle surface technology for protein immobilization, and a range of protein micro-array services, such as assay development and support. The company serves researchers, clinical centers, and biotech and pharmaceutical firms. Founded in 2006 and headquartered in Sioux Falls, South Dakota, Inanovate has an additional office in Raleigh, North Carolina, and operates in the United States and the United Kingdom.

Lumedica specializes in developing low-cost, high-performance Optical Coherence Tomography (OCT) imaging technologies. The company is focused on bringing its first fully patented OCT device to market, which aims to enhance the monitoring and detection of eye diseases by providing detailed imaging of the retina and related structures. Lumedica's technology leverages advanced optical components to improve eye imaging capabilities, allowing eye specialists to identify abnormalities and monitor minute changes in the eye effectively. The firm has a strong background in scientific innovation and product development and is currently supported by grants from the National Institutes of Health and the State of North Carolina.

Benanova specializes in developing environmentally benign nanoparticle systems for various industries, including disinfectants, cosmetics, and agriculture. The company's innovative Environmentally-benign Nanoparticles (EbNPs) are crafted from natural materials, offering high efficacy while being safe for both humans and the environment. These proprietary nanoparticles are reportedly 100 times more effective than traditional nanosilver, positioning them as advanced alternatives for antimicrobial and antifungal applications. Benanova is also working on customized solutions aimed at reducing chemical use in agricultural practices by up to 90%, thus minimizing environmental impact and costs associated with crop protection. The technology behind these products was developed by researchers at North Carolina State University, and the focus on sustainable, advanced functionality reflects Benanova's commitment to creating lasting benefits for consumers, society, and nature.

MuukTest is a software testing platform based in Raleigh, North Carolina, founded in 2019. The company specializes in codeless test automation, allowing software developers to create, execute, and manage automated tests efficiently. By leveraging artificial intelligence, MuukTest enhances testing productivity, reportedly increasing it by up to 26 times. This innovation enables clients to minimize the time spent on manual testing processes and infrastructure management, allowing them to concentrate on more valuable tasks within their software development lifecycle.

RENCI develops and deploys advanced technologies to enable research discoveries and practical innovations. RENCI collaborates with researchers, government, and industry to engage and solve problems affecting North Carolina, the United States, and the world. RENCI is a critical catalyst for data-driven discoveries that lead to improved health, a safer environment, and increased economic and business success.

Ecoclosure, founded in 2019 and based in Charlotte, North Carolina, specializes in regenerable building enclosures designed for commercial, industrial, and residential applications. The company focuses on developing technology that aims to improve indoor air quality while reducing energy consumption in buildings. Its innovative enclosures are equipped with monitoring and automation features, allowing for customized solutions tailored to various building programs, climate zones, and orientations. By prioritizing the creation of healthy indoor environments, Ecoclosure enhances occupant well-being and revitalizes indoor air quality.

Third Floor Materials, founded in 2016 and based in Raleigh, North Carolina, specializes in algorithmic technology that enhances infrared spectroscopy and optical components for specialized infrared applications. The company employs various advanced manufacturing techniques, including magnetron sputtering, plasma-assisted molecular beam epitaxy, pulsed laser deposition, resistive and e-beam evaporation, metal-organic vapor phase epitaxy, and chemical solution deposition. These methods enable Third Floor Materials to provide coating services on diverse substrate materials and shapes. Through its innovative technology, the company supports users in photonic design, concept development, and feasibility studies.

Kampanics is a research and development company based in Oak Ridge, North Carolina, specializing in microacoustic devices and piezomems technology. Founded by Kushal Bhattacharjee, the company focuses on assisting clients in areas such as signal processing, sensing, and energy harvesting. By collaborating with academic institutions, corporate partners, and industry experts, Kampanics aims to facilitate the development of innovative products and services in these technological fields.

Microgrid Labs, Inc. is a software and consulting company based in Durham, North Carolina, specializing in the development of solutions for microgrids, electric vehicle infrastructure, and solar forecasting. Founded in 2015, the company focuses on planning and modeling for fleet electrification and microgrid projects, offering services that include initial assessments, feasibility studies, and simulation. By providing consulting and software solutions, Microgrid Labs supports clients throughout the implementation and operations phases, helping them design economically viable projects while optimizing energy storage and management systems.

Benanova specializes in developing environmentally benign nanoparticle systems for various industries, including disinfectants, cosmetics, and agriculture. The company's innovative Environmentally-benign Nanoparticles (EbNPs) are crafted from natural materials, offering high efficacy while being safe for both humans and the environment. These proprietary nanoparticles are reportedly 100 times more effective than traditional nanosilver, positioning them as advanced alternatives for antimicrobial and antifungal applications. Benanova is also working on customized solutions aimed at reducing chemical use in agricultural practices by up to 90%, thus minimizing environmental impact and costs associated with crop protection. The technology behind these products was developed by researchers at North Carolina State University, and the focus on sustainable, advanced functionality reflects Benanova's commitment to creating lasting benefits for consumers, society, and nature.

VitalFlo Inc. is a digital health company based in Raleigh, North Carolina, established in 2017. It specializes in manufacturing handheld spirometers for asthmatic patients, allowing them to monitor their lung health and medication use. In addition to the spirometers, VitalFlo develops software that connects patients with chronic respiratory conditions to their healthcare providers. The company's remote monitoring system tracks lung function and environmental factors that may trigger asthma attacks, providing actionable insights to clinical teams. This innovative approach aims to reduce emergency room visits by offering timely recommendations to patients, thereby redefining asthma management and enhancing overall care.

North Carolina A&T State University is so many things to so many people, both in our state and around the country. North Carolina A&T State University is an HBCU. We are a top-flight research university, the largest historically black university (HBCU) in the country, the #1 producer of degrees awarded to African Americans in North Carolina and nationally recognized or our excellence in science, technology, mathematics and engineering (STEM) education. We are a diverse community, bound by intense pride and tradition, with fiercely loyal alumni who hold positions of importance and influence in companies and government agencies across the state, the country and the world. We are achievers, driven by a curious, limitless, fearless spirit that fuels discovery and innovation, resulting in 41 patents issued based on our research, as well as numerous spin-off and start-up companies. We are inclusive and welcoming, with students from many backgrounds and cultures, every part of our state, our nation and countries around the globe. We are passionate, driven by a desire to do more, be more and make more of a difference. Since we opened our doors in 1892, we have focused on giving every student the hands-on opportunities, core knowledge and global perspective that will lead them to make real and lasting change in their lives and the lives of others. At N.C. A&T, we have so much to be proud of, and you can learn more about those "Points of Pride" here. You can also use the links below to learn more about what makes N.C. A&T unique, from our leadership and history to our many rankings and recognitions.

The University of North Carolina at Greensboro, also known as UNCG and UNC Greensboro, is a public coeducational and research university in Greensboro in North Carolina in the United States of America, and it is a constituent institution of the system of the University of North Carolina. However, the University of North Carolina at Greensboro is a stand-alone university and awards its own degrees like all members of the system of the University of North Carolina . The Southern Association of Colleges and Schools Commission on Colleges accredits the University of North Carolina at Greensboro to award baccalaureate, masters, specialist, and doctoral degrees.

3i Nanotech, founded in 2018 and located in Greensboro, North Carolina, specializes in developing point-of-care technology for the monitoring of protein biomarkers in human samples. The company's innovative platform employs a proprietary system for biomarker identification, which aids in the early detection of cardiac biomarkers and infectious diseases. By providing medical professionals with advanced prehospital testing capabilities, 3i Nanotech enhances the capacity for timely diagnosis of infections, thereby improving patient care and outcomes.

Telli Technologies develops sensors for SiC and GaN power electronics. The company was founded in 2016 and is headquartered in Charlotte, North Carolina.

Allumia, LLC specializes in energy efficiency solutions, focusing on lighting upgrades for commercial, athletic, automotive, and industrial sectors. Founded in 2013 and headquartered in Seattle, Washington, with additional offices in Los Angeles and Durham, the company designs, funds, installs, and manages lighting projects. Allumia evaluates existing lighting systems and provides tailored proposals that include updated designs and anticipated savings. The company also supplies replacement lamps, drivers, and other lighting hardware, along with ongoing maintenance services. Utilizing a software and Internet of Things platform, Allumia streamlines the financing and management of energy efficiency projects, enabling clients to achieve complete equipment upgrades at reduced costs while maximizing energy savings. The company serves customers directly and collaborates with utility partners to enhance the efficiency of their operations across the nation.

Genoverde Biosciences is a biotechnology company based in Raleigh, North Carolina, founded in 2015. The company specializes in developing cell wall gene technology aimed at enhancing lignocellulosic energy crops, which are crucial for producing liquid fuels from plant sugars. By improving the secondary cell wall thickness of non-food bioenergy crops, Genoverde's technology increases biomass yield, allowing farmers to generate higher revenue through greater wood density. This innovation not only supports the production of bioenergy but also contributes to the sustainability of energy resources derived from plant materials.

Lumedica specializes in developing low-cost, high-performance Optical Coherence Tomography (OCT) imaging technologies. The company is focused on bringing its first fully patented OCT device to market, which aims to enhance the monitoring and detection of eye diseases by providing detailed imaging of the retina and related structures. Lumedica's technology leverages advanced optical components to improve eye imaging capabilities, allowing eye specialists to identify abnormalities and monitor minute changes in the eye effectively. The firm has a strong background in scientific innovation and product development and is currently supported by grants from the National Institutes of Health and the State of North Carolina.

Appia is a prominent mobile user acquisition network that specializes in delivering mobile app downloads to over 1 billion users across 200 countries. The company provides a marketplace platform for mobile application developers, offering them a distribution point while enabling advertisers to acquire high-value customers. Appia's advanced technology and extensive network ensure that applications reach a large and engaged audience, maximizing app installs and profit per install for its clients. With a diverse portfolio of trusted brands, Appia has established itself as a leader in mobile app discovery. The company operates from offices in San Francisco, California, and Durham, North Carolina, along with global sales offices, and has gained recognition for its rapid growth and innovation in the mobile advertising space.

High Road Learning promotes a dual-language approach to personalizing English-language learners' literacy growth. The company is based in Raleigh, North Carolina.

Benanova specializes in developing environmentally benign nanoparticle systems for various industries, including disinfectants, cosmetics, and agriculture. The company's innovative Environmentally-benign Nanoparticles (EbNPs) are crafted from natural materials, offering high efficacy while being safe for both humans and the environment. These proprietary nanoparticles are reportedly 100 times more effective than traditional nanosilver, positioning them as advanced alternatives for antimicrobial and antifungal applications. Benanova is also working on customized solutions aimed at reducing chemical use in agricultural practices by up to 90%, thus minimizing environmental impact and costs associated with crop protection. The technology behind these products was developed by researchers at North Carolina State University, and the focus on sustainable, advanced functionality reflects Benanova's commitment to creating lasting benefits for consumers, society, and nature.

Microgrid Labs, Inc. is a software and consulting company based in Durham, North Carolina, specializing in the development of solutions for microgrids, electric vehicle infrastructure, and solar forecasting. Founded in 2015, the company focuses on planning and modeling for fleet electrification and microgrid projects, offering services that include initial assessments, feasibility studies, and simulation. By providing consulting and software solutions, Microgrid Labs supports clients throughout the implementation and operations phases, helping them design economically viable projects while optimizing energy storage and management systems.

VitalFlo Inc. is a digital health company based in Raleigh, North Carolina, established in 2017. It specializes in manufacturing handheld spirometers for asthmatic patients, allowing them to monitor their lung health and medication use. In addition to the spirometers, VitalFlo develops software that connects patients with chronic respiratory conditions to their healthcare providers. The company's remote monitoring system tracks lung function and environmental factors that may trigger asthma attacks, providing actionable insights to clinical teams. This innovative approach aims to reduce emergency room visits by offering timely recommendations to patients, thereby redefining asthma management and enhancing overall care.

Techverse, Inc., established in 1997 and based in Cary, North Carolina, is a research and development firm specializing in advanced energy generation and utilization concepts. The company offers consulting services, including process design, model simulations, and experimental studies, to improve process and energy efficiency. Techverse utilizes specialized membrane separation processes and conducts laboratory, pilot, and full-scale experimental studies to develop and optimize energy-efficient technologies. The company operates on an as-needed basis, renting laboratory and office space from the First Flight Venture Center, and collaborates with partners to access specialized facilities. Techverse generates revenue through consulting services and industrial customer contracts, while also securing government funding, primarily through the SBIR program. Dr. Ashok Damle serves as the founder and president of Techverse, Inc.

MAA Laboratories is a pharmaceutical company specializing in the development of innovative nanotechnology for drug delivery. Founded in 2013 and headquartered in Durham, North Carolina, the company focuses on creating small, water-soluble drug molecules using its proprietary NanoCont technology. This technology enables the formulation of oral nanomedicines that address various challenges related to drug delivery and solubility. MAA Laboratories is actively engaged in developing medications for conditions such as Alzheimer’s disease and migraines, serving clients in the pharmaceutical industry with its advanced drug development platform.

Redbud Labs, Inc. specializes in the development and manufacturing of MEMS and microfluidics technologies tailored for the life science industry. The company produces actuated surface-attached posts films, which facilitate the manipulation of fluids, cells, and reagents at the microscale, thereby enhancing mixing efficiency and reducing assay times. Additionally, Redbud Labs is known for its innovative MXR, the first fully modular microfluidic mixer, utilized by leading biotechnology firms to enhance assay performance. The company offers cartridge-based automated sample preparation platforms, which simplify laboratory workflows while maintaining high performance. Founded in 2010 and based in Chapel Hill, North Carolina, Redbud Labs draws on advanced research from the University of North Carolina to provide solutions that address complex microfluidic challenges in research, drug discovery, and diagnostics.

Microgrid Labs, Inc. is a software and consulting company based in Durham, North Carolina, specializing in the development of solutions for microgrids, electric vehicle infrastructure, and solar forecasting. Founded in 2015, the company focuses on planning and modeling for fleet electrification and microgrid projects, offering services that include initial assessments, feasibility studies, and simulation. By providing consulting and software solutions, Microgrid Labs supports clients throughout the implementation and operations phases, helping them design economically viable projects while optimizing energy storage and management systems.

Metalytics is a biotechnology company based in Morrisville, NC, founded in 2016. The firm specializes in cell factory analysis, offering technology-enabled services designed to assist cell engineers in the biotechnology and pharmaceutical sectors. Its flagship product, CoreMFATM, facilitates optimal cell line selection and identifies the best conditions for cell line production. Metalytics' services enable the mapping of metabolism within industrial cell factories, allowing for the determination of metabolic rates in living cells, which is otherwise difficult to measure. This capability aids synthetic biology and pharmaceutical companies in enhancing their production processes and addressing complex production challenges, ultimately contributing to a deeper understanding of metabolic pathways.

BTI Targetry specializes in the development and deployment of high-performance targets for radionuclide production. The company was founded in 2002 and is headquartered in Cary, North Carolina.

Roundtable Analytics, Inc. specializes in developing predictive analytics software solutions tailored for the healthcare sector. The company provides OptimizED, a platform designed to enhance performance improvement initiatives by utilizing advanced predictive analytics and simulation modeling. This tool aims to optimize patient flow, reduce walk-outs, maximize resource utilization, minimize practice variability, and uncover new revenue opportunities. OptimizED serves as an insights platform for emergency departments, equipping teams with both historical and real-time data to benchmark and track performance while identifying areas for improvement. Founded in 2013 and headquartered in Durham, North Carolina, Roundtable Analytics combines expertise from mathematics, statistics, computer science, and operations research to address significant challenges within the healthcare industry.

Genoverde Biosciences is a biotechnology company based in Raleigh, North Carolina, founded in 2015. The company specializes in developing cell wall gene technology aimed at enhancing lignocellulosic energy crops, which are crucial for producing liquid fuels from plant sugars. By improving the secondary cell wall thickness of non-food bioenergy crops, Genoverde's technology increases biomass yield, allowing farmers to generate higher revenue through greater wood density. This innovation not only supports the production of bioenergy but also contributes to the sustainability of energy resources derived from plant materials.

Alievio, Inc. is an innovative medical device company based in Research Triangle Park, North Carolina, focused on developing solutions for glaucoma patients. The company has introduced Sollevio, a novel noninvasive device designed for the titration of postoperative intraocular pressure in individuals with refractory glaucoma. This device aims to address the complications commonly associated with traditional glaucoma surgeries and offers ophthalmologists a new tool to halt the progression of the disease. Founded in 2010 and originally known as Camras Vision, Inc., Alievio rebranded in June 2019 to reflect its commitment to advancing glaucoma treatment.

Akoustis Technologies, Inc. is a high-tech semiconductor company based in Huntersville, North Carolina, that specializes in the development, design, manufacturing, and sale of radio frequency (RF) filter products for the mobile wireless device industry. Established in 2013, the company operates through two main segments: Foundry Fabrication Services and RF Filters. The Foundry Fabrication Services segment offers engineering review and semiconductor wafer-manufacturing services, while the RF Filters segment focuses on producing innovative amplifier and filter products for various applications, including smartphones, tablets, cellular infrastructure, Wi-Fi equipment, and military uses. Akoustis utilizes a proprietary microelectromechanical systems-based technology known as XBAW to create its filters, enabling efficient production and unique performance characteristics. The company generates revenue primarily through individual customer purchase orders.

Redbud Labs, Inc. specializes in the development and manufacturing of MEMS and microfluidics technologies tailored for the life science industry. The company produces actuated surface-attached posts films, which facilitate the manipulation of fluids, cells, and reagents at the microscale, thereby enhancing mixing efficiency and reducing assay times. Additionally, Redbud Labs is known for its innovative MXR, the first fully modular microfluidic mixer, utilized by leading biotechnology firms to enhance assay performance. The company offers cartridge-based automated sample preparation platforms, which simplify laboratory workflows while maintaining high performance. Founded in 2010 and based in Chapel Hill, North Carolina, Redbud Labs draws on advanced research from the University of North Carolina to provide solutions that address complex microfluidic challenges in research, drug discovery, and diagnostics.

SonoVol, Inc. specializes in developing and manufacturing ultrasound imaging systems tailored for the biotechnology and pharmaceutical sectors. The company's flagship product, Vega, is a preclinical imaging platform that utilizes acoustic angiography technology. Designed to streamline the preclinical screening process, the fully automated benchtop platform enables researchers in pharmaceutical, biotech, government, and academic markets to efficiently assess tumor size, location, morphology, and vascular density. Its robotic motion control ensures precise transducer movement, leading to consistent results across studies, regardless of the user. Founded in 2012 and headquartered in Durham, North Carolina, SonoVol aims to enhance the capabilities of researchers and clinicians in detecting and treating tumors effectively.

BTI Targetry specializes in the development and deployment of high-performance targets for radionuclide production. The company was founded in 2002 and is headquartered in Cary, North Carolina.

Edison Agrosciences, Inc. is an agricultural biotechnology company based in Durham, North Carolina, focused on developing innovative solutions for producing plant-based industrial materials. Founded in 2013, the company primarily aims to create alternative rubber crops for various applications, including consumer, medical, and industrial products. Edison employs advanced computational breeding and agronomic techniques to enhance rubber concentration in underutilized plant parts, thereby improving yield per acre. The company is building a robust intellectual property portfolio and forming strategic partnerships to support the validation of its crop and product innovations. With a leadership team experienced in the industry, Edison Agrosciences is committed to providing sustainable biomaterials through its agricultural practices.

Roundtable Analytics, Inc. specializes in developing predictive analytics software solutions tailored for the healthcare sector. The company provides OptimizED, a platform designed to enhance performance improvement initiatives by utilizing advanced predictive analytics and simulation modeling. This tool aims to optimize patient flow, reduce walk-outs, maximize resource utilization, minimize practice variability, and uncover new revenue opportunities. OptimizED serves as an insights platform for emergency departments, equipping teams with both historical and real-time data to benchmark and track performance while identifying areas for improvement. Founded in 2013 and headquartered in Durham, North Carolina, Roundtable Analytics combines expertise from mathematics, statistics, computer science, and operations research to address significant challenges within the healthcare industry.

Akoustis Technologies, Inc. is a high-tech semiconductor company based in Huntersville, North Carolina, that specializes in the development, design, manufacturing, and sale of radio frequency (RF) filter products for the mobile wireless device industry. Established in 2013, the company operates through two main segments: Foundry Fabrication Services and RF Filters. The Foundry Fabrication Services segment offers engineering review and semiconductor wafer-manufacturing services, while the RF Filters segment focuses on producing innovative amplifier and filter products for various applications, including smartphones, tablets, cellular infrastructure, Wi-Fi equipment, and military uses. Akoustis utilizes a proprietary microelectromechanical systems-based technology known as XBAW to create its filters, enabling efficient production and unique performance characteristics. The company generates revenue primarily through individual customer purchase orders.

Alievio, Inc. is an innovative medical device company based in Research Triangle Park, North Carolina, focused on developing solutions for glaucoma patients. The company has introduced Sollevio, a novel noninvasive device designed for the titration of postoperative intraocular pressure in individuals with refractory glaucoma. This device aims to address the complications commonly associated with traditional glaucoma surgeries and offers ophthalmologists a new tool to halt the progression of the disease. Founded in 2010 and originally known as Camras Vision, Inc., Alievio rebranded in June 2019 to reflect its commitment to advancing glaucoma treatment.

GridBridge, Inc. specializes in designing, developing, and deploying advanced power delivery solutions aimed at modernizing power systems. Founded in 2012 and based in Raleigh, North Carolina, the company focuses on enhancing distribution efficiency and reliability through its innovative Energy Router technology. This platform integrates renewable energy generation and energy storage, significantly optimizing electric distribution flow. GridBridge serves both consumers and electric utilities, providing versatile and dependable solutions to support the evolution of power systems. As of 2017, it operates as a subsidiary of Electric Research and Manufacturing Cooperative, Inc.

InfoSense is a technology-driven company established in 2007 as a spin-off from the University of North Carolina at Charlotte, focusing on commercializing an innovative acoustic inspection technology developed by Dr. Ivan Howitt. The company specializes in creating tools for rapid assessment of sewer lines, enabling the non-invasive detection of blockages in small-diameter gravity sewers. By employing a patented active transmit and receive method, InfoSense's technology allows for quick inspections, providing blockage assessment in under three minutes at a significantly lower cost than traditional methods. This technology enables wastewater operators to efficiently target pipe cleaning resources, enhancing overall maintenance and operational effectiveness within the wastewater collection industry.

SonoVol, Inc. specializes in developing and manufacturing ultrasound imaging systems tailored for the biotechnology and pharmaceutical sectors. The company's flagship product, Vega, is a preclinical imaging platform that utilizes acoustic angiography technology. Designed to streamline the preclinical screening process, the fully automated benchtop platform enables researchers in pharmaceutical, biotech, government, and academic markets to efficiently assess tumor size, location, morphology, and vascular density. Its robotic motion control ensures precise transducer movement, leading to consistent results across studies, regardless of the user. Founded in 2012 and headquartered in Durham, North Carolina, SonoVol aims to enhance the capabilities of researchers and clinicians in detecting and treating tumors effectively.

The Center for the Environmental Implications of NanoTechnology (CEINT) is exploring the relationship between a vast array of nanomaterials— from natural, to manufactured, to those produced incidentally by human activities— and their potential environmental exposure, biological effects, and ecological impacts. Headquartered at Duke University, CEINT is a collaborative effort bringing together researchers from Duke, Carnegie Mellon University, Howard University, Virginia Tech, University of Kentucky, and Stanford University. CEINT academic collaborations include on-going activities coordinated with faculty at Baylor, Clemson, North Carolina State, and North Carolina Central universities, with researchers at NIST and EPA government labs, and with key international partners.

Xanofi, Inc. is a nanotechnology company based in Raleigh, North Carolina, specializing in the development and production of nanofibers from polymers. Established in 2010, Xanofi has introduced a new platform process that significantly enhances the efficiency of nanofiber manufacturing. This innovative approach allows for the easy integration of nanofiber production into existing manufacturing environments, enabling businesses to produce short and staple nanofibers at high yields. By providing advanced nanofiber components, Xanofi is transforming the way nanofibers are utilized across various applications, particularly in processes that require the spraying or dispersion of liquids for wetlaid manufacturing.

GrassRoots Biotechnology, based in Durham, North Carolina, specializes in genomic technologies aimed at enhancing crop production. The company focuses on gene expression and various agricultural technologies to develop improved biofuel feedstocks, including biomass crops like switchgrass and sorghum. By conducting research in these areas, GrassRoots Biotechnology aims to enable farmers to cultivate more productive and sustainable crops, contributing to advancements in agricultural practices and biofuel production.

GridBridge, Inc. specializes in designing, developing, and deploying advanced power delivery solutions aimed at modernizing power systems. Founded in 2012 and based in Raleigh, North Carolina, the company focuses on enhancing distribution efficiency and reliability through its innovative Energy Router technology. This platform integrates renewable energy generation and energy storage, significantly optimizing electric distribution flow. GridBridge serves both consumers and electric utilities, providing versatile and dependable solutions to support the evolution of power systems. As of 2017, it operates as a subsidiary of Electric Research and Manufacturing Cooperative, Inc.

Alievio, Inc. is an innovative medical device company based in Research Triangle Park, North Carolina, focused on developing solutions for glaucoma patients. The company has introduced Sollevio, a novel noninvasive device designed for the titration of postoperative intraocular pressure in individuals with refractory glaucoma. This device aims to address the complications commonly associated with traditional glaucoma surgeries and offers ophthalmologists a new tool to halt the progression of the disease. Founded in 2010 and originally known as Camras Vision, Inc., Alievio rebranded in June 2019 to reflect its commitment to advancing glaucoma treatment.

Agile Sciences is a biotechnology company based in Raleigh, North Carolina, specializing in solutions for the biopharma industry. Founded in 2007, the company focuses on addressing the challenges posed by antibiotic resistance and biofilms. Agile Sciences is developing biopharmaceuticals that utilize aminoimidazole small molecules to inhibit bacterial resistance mechanisms, thereby enhancing the efficacy of existing antibiotics. This innovative approach aims to provide effective treatments for life-threatening infections, particularly in patients with conditions such as cystic fibrosis and chronic wounds. Through its dedicated research and development efforts, Agile Sciences seeks to improve the options available to healthcare providers in combating antibiotic-resistant infections.

EnSolve Biosystems, Inc. is a biotechnology company based in Raleigh, North Carolina, that focuses on developing and manufacturing solutions for filtering and cleaning maritime and industrial waste. The company's product lineup includes PetroLiminator, which effectively separates oil from water, and GF 2010, a liquid detergent designed to dissolve and biologically consume grease and oils. Additionally, EnSolve offers EnCell, which eliminates organic wastes from water, and EnFlow, a technology that employs catalytic and biotechnological processes for air filtration. The company was founded in 1995 and is committed to providing innovative solutions for environmental cleanup and waste management.