National Science Foundation

The National Science Foundation (NSF) is an independent federal agency established in 1950 and based in Alexandria, Virginia. It is dedicated to supporting research and education in science and engineering across a wide range of disciplines. The NSF provides significant non-dilutive funding, up to $1.5 million, to startups and small businesses through its America's Seed Fund initiative, which is part of the Small Business Innovation Research (SBIR) program mandated by Congress. With an operating budget of approximately $7.8 billion, the NSF is committed to advancing fundamental research and education, thus fostering innovation and technological development in the United States.

James Donlon

Program Director

Hayes, Kenneth B.

Innovation Corps (I-Corps) Adjunct Instructor

Sethuraman Panchanathan

Director

Past deals in Non-Profit

The Institute for Integrative and Innovative Research (I³R) at the University of Arkansas is a new model of public research and economic development. It works with commercial, philanthropic, non-profit, and governmental organizations to deliver positive societal impact by bringing the discoveries of the future to the world in real-time.

Ocean

Grant in 2022
Ocean is a social enterprise that aims to provide low-income households in India with safe and affordable roofing. The company was founded in 2017 by Alexa Bednar and is based in Seattle, Washington.

CodeCrew

Grant in 2021
CodeCrew empowers kids from underrepresented communities to be tech innovators and leaders through practical, hands-on computer science training. Today, they have multiple summer camps, multiple after-school programs, eight in-school electives programs, a young adult Code School, and a number of special events.

Jet-Set Offset

Grant in 2021
Jet-Set Offset is a donation-based carbon-offsetting tool designed to address the environmental impact of air travel. It provides a consumer-friendly alternative to traditional carbon marketplaces by facilitating automatic, mileage-based donations from travelers to nonprofit environmental organizations. When travelers or companies subscribe to Jet-Set Offset, they can support their chosen nonprofit with a contribution of one cent per mile flown. This innovative platform connects eco-conscious travelers with organizations focused on local climate solutions, including certified carbon offset projects, advocacy, education, renewable energy, reforestation, and conservation efforts. By raising awareness and encouraging action, Jet-Set Offset aims to inspire both individuals and businesses to contribute positively to the environment while traveling.

NLM Photonics

Grant in 2021
NLM Photonics is a semiconductor technology company focused on developing advanced electro-optic modulation technology aimed at enhancing networking, computing, and sensing applications. Originating from over two decades of research at the University of Washington, the company's patented Hybrid Organic Electro-Optic (OEO) Technology facilitates efficient data transfer between electronic components and photonics, which is crucial for applications like fiber optics and LIDAR. This technology addresses the power and bandwidth limitations of existing silicon photonics platforms by enabling low-voltage, low-power integration that can be retrofitted into existing manufacturing processes with minimal disruption. NLM's solutions provide significant improvements in power efficiency and scalable bandwidth, making them attractive to hyperscale data center operators and commercial fabs. The company's growth is supported by strategic partnerships with major industry players, enhancing its position in the rapidly evolving photonics landscape.

Impact Proteomics

Grant in 2021
Produces kits for protein sample preparation to enable better drug and biomarker discovery. vision is to be the leader of protein sample preparation, enabling the discovery of important therapeutics and diagnostics and bringing them to market faster than ever before.
Digital Harbor Foundation is comprised of people who love what they do and work hard day-in and day-out to make a difference in the lives of the youth they serve. They think hard about education, technology, and innovation, and work even harder to overcome the socio-economic barriers that impede forward progress for too many. They are not perfect but they care about their work and give it everything they have every day.

AgThera

Grant in 2020
AgThera is a biotechnology company focused on discovering, developing, and commercializing innovative antimicrobial medicines for infectious diseases. The company specializes in advanced probiotics that are engineered to effectively eliminate pathogens, including antibiotic-resistant bacteria. AgThera’s platform utilizes probiotic bacteria that express and secrete antimicrobial peptides, providing a novel approach to combatting infections. The company's research and development efforts are supported by grants from the US National Science Foundation and the US Department of Agriculture, enabling the advancement of its AI-enhanced R&D program. AgThera aims to facilitate the development of drugs for both human and livestock use, addressing the growing concern of antibiotic resistance in various medical and agricultural settings.

Unlocked Labs

Grant in 2020
Unlocked Labs specializes in developing innovative probiotics aimed at addressing chronic health conditions by utilizing genetically optimized microbial strains. The company focuses on activating dormant microbial abilities to effectively digest compounds that can lead to health issues. Their first product targets the risk of kidney stones by breaking down stone-forming compounds derived from healthy foods like leafy vegetables. Unlocked Labs employs alternative regulatory pathways to expedite the availability of safe and effective probiotic solutions for consumers. By harnessing the natural detoxifying capabilities of symbiotic microbes, their products aim to reduce acid levels in the body, making them both affordable and accessible to a wide audience.

Erisyon

Grant in 2020
Erisyon Inc. is a biotechnology company based in Austin, Texas, founded in 2018. It specializes in the research and development of a novel single molecule protein sequencer, which has the potential to revolutionize disease detection, treatment, and monitoring. The technology has diverse applications across several fields, including oncology for personalized cancer therapies, diagnostics for disease discovery, plant science for enhancing crop growth, drug development for creating new pharmaceuticals, and industrial biology. By leveraging over a decade of research from the University of Texas at Austin's Center for Systems and Synthetic Biology, Erisyon aims to contribute to advancements that promote health, safety, and abundance in society.

Impactivo Consulting

Grant in 2020
Impactivo is a social impact consulting firm that specializes in the field of health and healthcare, childhood and education and philanthropy. They produce solutions that translate research and policy to action and build systemic, operational and strategic funding capacity. Impactivo offers a wide array of services in Strategic Funding, Financial Sustainability, and Program Management to support leaders at the forefront of social innovation in making strategy and organization decisions that lead to exceptional results. They are dedicated to the development of positions that improve the health status, educational attainment, and general wellbeing of the people of people who live in Puerto Rico and abroad.

MathBRIX

Grant in 2019
MathBRIX is a for-profit EdTech business, with initial support from the National Science Foundation Small Business Research Program (NSF/SBIR). The venture is developing a SaaS math program for children 3-8, which emphasizes higher-order thinking skills and concept acquisition. Children are guided through visual puzzles and games designed to help them see the big ideas behind math, rather than memorize facts. Virtual toy building bricks take the place of traditional manipulatives, with studs on the surface representing numeric value. The platform adjusts to each child's level and comes with a suite of analytics that track learning outcomes. Off computer hands-on projects further extend learning. The MathBRIX mission is to create new learning technologies that will make a significant social and economic impact over time. For the US to remain a world economic leader, all children must be able to think mathematically and problem-solve. Children behind in kindergarten, often stay behind through the remaining school years. Only 40% of U.S. fourth grade students are deemed proficient on national math assessments. Early intervention is key. The visual strategies are derived from the federally-funded Comprehensive School Mathematics Program. Twenty years of research found CSMP students had greater ability to solve novel math problems. CSMP was effective with the gifted as well as the learning challenged. MathBRIX testing with over 500 students confirms high student engagement, feasibility, promise of learning. A larger test is underway in 34 districts nation-wide. In 2018, pre-school and parent education components will be developed with the Parents as Teachers National Center.

Ocean

Grant in 2019
Ocean is a social enterprise that aims to provide low-income households in India with safe and affordable roofing. The company was founded in 2017 by Alexa Bednar and is based in Seattle, Washington.

Camerad

Grant in 2019
This organization primarily operates in the Diagnostic Apparatus, Medical business / industry within the Measuring, Photographic, Medical, & Optical Goods, & Clocks sector. This organization has been operating for approximately a year.

INFINI D Learning

Grant in 2019
Infini-D Learning gives pupils the chance to creatively put what they learn in the classroom into practice. Each student's understanding of classroom material is tested in several subject areas with creative technical and social skill training through game-like simulation modules, compelling team assignments, and immersive surroundings. When a teacher uses it, they have access to an application that keeps them involved in the learning process, gives them the ability to teach their lessons, and brings the subject matter to life in a way that has never been possible before.
Arizona State University is a public research university located in Tempe, Arizona, offering a wide range of undergraduate, graduate, and professional programs across various disciplines. The institution emphasizes inclusivity and aims to measure its success by the diversity of its student body. Arizona State University engages in research initiatives that prioritize the public good, demonstrating a commitment to enhancing the economic, social, and cultural vitality of the surrounding communities. Through its comprehensive educational services, the university plays a vital role in fostering higher education and contributing to the overall development of the region.

Central Inventions

Grant in 2019
Central Inventions brings powerful engineering techniques to the classrooms and machine shops where future engineers learn. Comprised of both engineers and teachers, the organization wants all students to have equal access to technology, starting with critical math and science literacy topics. Central Inventions also seeks to helps students see and understand the power of engineering to solve complex problems via actionable solutions.

Impact Proteomics

Grant in 2019
Produces kits for protein sample preparation to enable better drug and biomarker discovery. vision is to be the leader of protein sample preparation, enabling the discovery of important therapeutics and diagnostics and bringing them to market faster than ever before.

The Local Crowd

Grant in 2018
The Local Crowd

BE MORE with Anu

Grant in 2018
BE MORE with Anu helps people and organizations maximize performance, increase profits, reduce wasted costs and meet diversity, equity and inclusion (DEI) goals and aspirations.

Digital Promise

Grant in 2018
Digital Promise provides support to advance technologies that can transform teaching and learning. It is a non-profit organization originated by the U.S. Congress as part of the 2008 re-authorization of the higher education opportunity act. Digital Promise was founded in 2011 and is based in Washington, District of Columbia.

Impactivo Consulting

Grant in 2017
Impactivo is a social impact consulting firm that specializes in the field of health and healthcare, childhood and education and philanthropy. They produce solutions that translate research and policy to action and build systemic, operational and strategic funding capacity. Impactivo offers a wide array of services in Strategic Funding, Financial Sustainability, and Program Management to support leaders at the forefront of social innovation in making strategy and organization decisions that lead to exceptional results. They are dedicated to the development of positions that improve the health status, educational attainment, and general wellbeing of the people of people who live in Puerto Rico and abroad.

AgThera

Grant in 2017
AgThera is a biotechnology company focused on discovering, developing, and commercializing innovative antimicrobial medicines for infectious diseases. The company specializes in advanced probiotics that are engineered to effectively eliminate pathogens, including antibiotic-resistant bacteria. AgThera’s platform utilizes probiotic bacteria that express and secrete antimicrobial peptides, providing a novel approach to combatting infections. The company's research and development efforts are supported by grants from the US National Science Foundation and the US Department of Agriculture, enabling the advancement of its AI-enhanced R&D program. AgThera aims to facilitate the development of drugs for both human and livestock use, addressing the growing concern of antibiotic resistance in various medical and agricultural settings.

TeraProbes

Grant in 2017
TeraProbes specializes in fully automated non-contact on-wafer probing systems. The company was founded in 2014 as a result of our research at The Ohio State University's Department of Electrical and Computer Engineering. We believe that our non-contact probing technology can help alleviate the pains associated with contact probe wear and tear, contact repeatability, and the extremely high hardware and operation costs associated with the on-wafer device and IC characterization in the high-speed electronics industry.

DuKorp Studio

Grant in 2017
DuKode Studio is a creative computing firm that focuses on forward-facing data transpositions to many forms, including software, animation, print, electronic machines, and physical objects for arts + culture, science, research, and nonprofit organizations.

Camerad

Grant in 2016
This organization primarily operates in the Diagnostic Apparatus, Medical business / industry within the Measuring, Photographic, Medical, & Optical Goods, & Clocks sector. This organization has been operating for approximately a year.
Biomed Simulation is improving clinician performance through patient-free simulation. They offer products that include lung simulators and beating heart simulators.

Strange Loop Games

Grant in 2016
Strange Loop Games creates a metaverse network of gaming worlds that are owned and governed by their citizens.
The Berkeley Engineering Fund is dedicated to supporting the University of California, Berkeley's College of Engineering by providing financial resources that enhance educational opportunities for students. This fund plays a crucial role in fostering academic excellence and innovation within the college, which is known for its diverse range of engineering and science programs. The college offers comprehensive services such as academic advising, tutoring, and career development to ensure students receive robust support throughout their educational journey. By contributing to the university's initiatives, the Berkeley Engineering Fund helps maintain the college's reputation for stellar research and quality education, ultimately benefiting both the institution and its students.

AgThera

Grant in 2016
AgThera is a biotechnology company focused on discovering, developing, and commercializing innovative antimicrobial medicines for infectious diseases. The company specializes in advanced probiotics that are engineered to effectively eliminate pathogens, including antibiotic-resistant bacteria. AgThera’s platform utilizes probiotic bacteria that express and secrete antimicrobial peptides, providing a novel approach to combatting infections. The company's research and development efforts are supported by grants from the US National Science Foundation and the US Department of Agriculture, enabling the advancement of its AI-enhanced R&D program. AgThera aims to facilitate the development of drugs for both human and livestock use, addressing the growing concern of antibiotic resistance in various medical and agricultural settings.

Uncopiers, Inc.

Grant in 2016
Uncopiers, Inc. is dedicated to developing environmentally responsible solutions to critical problems using its liquid fracture technology. Liquid fracture is a unique way of controlling and concentrating energy at nanometer length scales. One only needs silent sound and clean water to implement this chemical free, environmentally friendly, and energy efficient processing technique.

bioProtonics

Grant in 2015
bioProtonics provides the resolving power needed to measure the ultra-fine tissue changes that are the earliest harbingers of disease, thus enabling the most effective application of therapeutics. The company was founded in 2018 and is headquartered in Santa Barbara, California, United States.
The Center for Open Science (COS) is a non-profit organization building free tools for open scientific practices, including its flagship infrastructure Open Science Framework (osf.io).
American Society for Engineering Education is a nonprofit organization. They support engineering and engineering technology education, research, and careers. The organization develops policies and programs that enhance professional opportunities for engineering faculty members. Their activities support increased student enrollment in engineering and engineering technology colleges and universities.

US Ignite

Grant in 2015
US Ignite is a nonprofit organization based in Washington, D.C., founded in 2011 by Glenn Ricart and Joe Kochan. The organization focuses on developing next-generation applications aimed at providing transformative public benefits. US Ignite serves as an accelerator for technology research, supporting developers, communities, and individuals in creating innovative solutions that address societal challenges.
The Center for Open Science (COS) is a non-profit organization building free tools for open scientific practices, including its flagship infrastructure Open Science Framework (osf.io).

STEMKids

Grant in 2014
STEMKids builds tools and programs to connect America’s STEM experts with teachers, kids and administrators.

Up-Grade.me

Grant in 2014
Upgrademe Inc. is an innovative adaptive learning platform that can help anyone achieve their educational and career goals.

Purdue Research Park

Grant in 2013
The mission of the Purdue Research Foundation is to advance Purdue University's quest for preeminence in discovery, learning, and engagement through effective stewardship of assets. The Foundation seeks to: 1) Support Purdue's discovery, learning, and engagement priorities in close association with the University's strategic plan implementation and related administrative functions. 2) Provide flexibility of resources for their agile deployment. 3) Realize Purdue's technology transfer interests. 4) Oversee Purdue's intellectual property management. 5) Develop, manage, and deploy real estate and financial assets. 6) Engage Purdue Research Park resources to support business incubation. 7) Advance Purdue's role in economic development.

Dynamic Ideas

Grant in 2013
Dynamic Ideas’ mission is to publish scientific books that have quality and originality in the areas of Applied Mathematics, Operations.

The Fred Rogers

Grant in 2013
Founded by Fred Rogers in 1971 (as Family Communications, Inc.) to produce "Mister Rogers' Neighborhood" and other materials for children and families. This past year we changed our name to The Fred Rogers Company. We're proud to be building on Fred's legacy in innovative ways through a wide variety of media, and engaging new generations of children and families with his timeless wisdom.
EDC is a global nonprofit organization that designs, delivers and evaluates innovative programs to address some of the world's most urgent challenges in education, health, and economic opportunity. Working with public-sector and private partners, we harness the power of people and systems to improve education, health promotion and care, workforce preparation, communications technologies, and civic engagement.

MassChallenge

Grant in 2013
MassChallenge is a non-profit startup accelerator dedicated to supporting promising startups across various industries worldwide without taking equity. With locations in Boston, Israel, Mexico, Switzerland, Texas, and the UK, it offers expert mentorship, tailored curricula, and access to corporate partners, along with significant cash prizes for top startups. The organization fosters economic growth through programs like Bridge to MassChallenge in multiple countries and initiatives such as PULSE@MassChallenge, which focuses on digital health innovation. Additionally, MassChallenge has specialized programs like MassChallenge FinTech and MassChallenge HealthTech, designed to create partnerships between startups and established enterprises to drive innovation in financial services and digital health, respectively. To date, MassChallenge alumni have collectively raised over $2 billion in funding, generated approximately $900 million in revenue, and created over 65,000 jobs, underscoring its impact on the global innovation ecosystem.

SDIT Pro

Grant in 2012
SDIT Pro is an IT service and consulting firm that provides multiple services for its clients. SDIT Pro delivers services such as business IT support, network design, server design, business phone systems, IP cameras, home automation, and commercial and residential audio/video. SDIT Pro was established in San Diego, California.

Nanopareil

Grant in 2012
Nanopareil, LLC specializes in producing advanced separation modules made from functionalized nanofibers. Founded in 2011 and headquartered in Dakota Dunes, South Dakota, the company serves various industries, including biopharmaceuticals, biofuels, and water purification. Nanopareil's proprietary nanofiber filters utilize a randomly overlaid mat of electrospun nanofibers, offering a unique separation medium that enables both size-based and adsorptive separation. This innovative approach enhances process efficiencies and economics, making it particularly valuable for applications in biopharmaceutical production, water treatment, and air purification. By reducing processing times, minimizing waste, and decreasing the required volume of separation media, Nanopareil supports biomedical researchers in lowering costs and improving manufacturing processes. The company is a subsidiary of ProMetic BioSciences Ltd. as of September 2020.

Uncopiers, Inc.

Grant in 2011
Uncopiers, Inc. is dedicated to developing environmentally responsible solutions to critical problems using its liquid fracture technology. Liquid fracture is a unique way of controlling and concentrating energy at nanometer length scales. One only needs silent sound and clean water to implement this chemical free, environmentally friendly, and energy efficient processing technique.
EDC is a global nonprofit organization that designs, delivers and evaluates innovative programs to address some of the world's most urgent challenges in education, health, and economic opportunity. Working with public-sector and private partners, we harness the power of people and systems to improve education, health promotion and care, workforce preparation, communications technologies, and civic engagement.
DVIRC is a leading private, non-profit economic development organization established in 1988 to serve the needs of nearly 5,000 Small to Midsized advanced manufacturing Enterprises (SME) in five counties throughout the Philadelphia region. The organization's primary focus is to grow business value for clients through consulting services, talent development and regional, state and federal resource assistance, helping to establish the region as an internationally recognized leader in manufacturing competitiveness. We believe growing business value improves the standard of living and quality of life for those that live and/or work in the region. A diverse board of directors comprised of executives from the manufacturing, banking, legal and economic development communities govern the DVIRC.

Uncopiers, Inc.

Grant in 2010
Uncopiers, Inc. is dedicated to developing environmentally responsible solutions to critical problems using its liquid fracture technology. Liquid fracture is a unique way of controlling and concentrating energy at nanometer length scales. One only needs silent sound and clean water to implement this chemical free, environmentally friendly, and energy efficient processing technique.

Uncopiers, Inc.

Grant in 2009
Uncopiers, Inc. is dedicated to developing environmentally responsible solutions to critical problems using its liquid fracture technology. Liquid fracture is a unique way of controlling and concentrating energy at nanometer length scales. One only needs silent sound and clean water to implement this chemical free, environmentally friendly, and energy efficient processing technique.

Uncopiers, Inc.

Grant in 2007
Uncopiers, Inc. is dedicated to developing environmentally responsible solutions to critical problems using its liquid fracture technology. Liquid fracture is a unique way of controlling and concentrating energy at nanometer length scales. One only needs silent sound and clean water to implement this chemical free, environmentally friendly, and energy efficient processing technique.

Uncopiers, Inc.

Grant in 2006
Uncopiers, Inc. is dedicated to developing environmentally responsible solutions to critical problems using its liquid fracture technology. Liquid fracture is a unique way of controlling and concentrating energy at nanometer length scales. One only needs silent sound and clean water to implement this chemical free, environmentally friendly, and energy efficient processing technique.

Uncopiers, Inc.

Grant in 2005
Uncopiers, Inc. is dedicated to developing environmentally responsible solutions to critical problems using its liquid fracture technology. Liquid fracture is a unique way of controlling and concentrating energy at nanometer length scales. One only needs silent sound and clean water to implement this chemical free, environmentally friendly, and energy efficient processing technique.

Uncopiers, Inc.

Grant in 2004
Uncopiers, Inc. is dedicated to developing environmentally responsible solutions to critical problems using its liquid fracture technology. Liquid fracture is a unique way of controlling and concentrating energy at nanometer length scales. One only needs silent sound and clean water to implement this chemical free, environmentally friendly, and energy efficient processing technique.

Uncopiers, Inc.

Grant in 2002
Uncopiers, Inc. is dedicated to developing environmentally responsible solutions to critical problems using its liquid fracture technology. Liquid fracture is a unique way of controlling and concentrating energy at nanometer length scales. One only needs silent sound and clean water to implement this chemical free, environmentally friendly, and energy efficient processing technique.

Uncopiers, Inc.

Grant in 2001
Uncopiers, Inc. is dedicated to developing environmentally responsible solutions to critical problems using its liquid fracture technology. Liquid fracture is a unique way of controlling and concentrating energy at nanometer length scales. One only needs silent sound and clean water to implement this chemical free, environmentally friendly, and energy efficient processing technique.
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