Gossamer Bio is a San Diego-based company focused on the discovery and development of novel and differentiated therapeutic products, to address high unmet needs amongst various targeted patient populations. Founded by the former Receptos executive team, Gossamer Bio’s strategy will be to leverage an asset-rich in-licensing environment, with a focus on areas of high unmet need, utilizing a team with a strong track record of execution in immunology, inflammation, fibrosis and oncology.
Senti Biosciences is a biotechnology company focused on synthetic biology and gene circuit engineering for therapeutic applications. Senti Bio utilizes a synthetic biology platform named Gene Circuits to develop therapies that offer improved precision and control. These circuits are engineered to selectively eliminate cancer cells while sparing healthy ones, enhancing specificity for target cells, and regulating drug expression post-administration.
Celcuity is a clinical-stage biotechnology company translating discoveries of new cancer sub-types into pioneering companion diagnostics and expanded therapeutic options for cancer patients. Celcuity's 3rd generation diagnostic platform, CELsignia, analyzes living tumor cells to untangle the complexity of the cellular activity driving a patient's cancer. This allows Celcuity to discover new cancer sub-types molecular diagnostics cannot detect. Celcuity is driven to improve outcomes for patients and to transform how pharmaceutical companies define the patient populations for their targeted therapies.
Splice Bio is a gene therapy company based on technology developed in the Muir Lab at Princeton University. The company is developing novel gene therapies based on its proprietary intein platform technology to treat patients that suffer from incurable genetic diseases. The company’s platform has the potential to address two existing limitations of adeno-associated viruses (AAVs), both by increasing the size of the cargo gene that can be delivered and by expanding the range of tissues that can be targeted.
Korro Bio provides an efficient and selective method for RNA editing, leveraging natural processes common to all multi-cellular organisms. Korro Bio was created to lead the field of RNA editing. The company is advancing a proprietary platform designed to selectively edit messenger RNA and recode specific codons to effect changes in protein structure and function across multiple tissues. In 2018,
InCarey is a leading domestic comprehensive service platform focusing on the management of patients with chronic diseases and vertical diseases. It is committed to providing one-stop Internet medical, pharmaceutical, and medical services for patients with long-term, heavy-service, and high-value chronic diseases. Innovative payment services.
Belong Health works with local health plans to provide regionally informed, humanistic care to a rapidly expanding community of need.
NeueHealth is a health care service platform that focuses on improving patient experiences and outcomes through a combination of technology and local healthcare resources. It operates 61 affiliated primary care clinics that deliver both virtual and in-person clinical care to nearly 75,000 unique patients. NeueHealth is part of Bright Health Group, which also offers Medicare and commercial health plan products to approximately 623,000 consumers across 14 states. The company aims to reduce healthcare costs while enhancing access and quality of care by aligning the interests of consumers, providers, and payers. Founded in 2015 and based in Minneapolis, Minnesota, NeueHealth leverages intelligent technology to connect users with healthcare services and providers effectively.
AviadoBio mission is to transform the lives of people living with neurodegenerative disorders by developing and delivering transformative gene therapies for diseases including frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). The Company’s technology is based on pioneering research from King’s College London and the UK Dementia Research Institute.
Recludix pharma is a developing platform to discover potent and selective inhibitors of challenging protein targets. The platform approach integrates custom generated DNA-encoded libraries, massively parallel determination of structure-activity relationships, and a proprietary screening tool to ensure selectivity.
858 Therapeutics is a biotechnology company focused on discovering small molecule therapeutics for novel targets in oncology and immunology. The company emphasizes innovative approaches in synthetic lethality, innate immunity, and RNA modulation. Its lead program is a PARG inhibitor currently in early clinical development.
Vori Health offers a new care delivery model for treating musculoskeletal conditions. Its nationwide, all-inclusive medical practice is evidence-based and uniquely positioned to address a multitude of back, neck, and other joint issues. The organization offers integrated medical and rehabilitation care, physical therapy, prescriptions, imaging and lab ordering, health coaching, nutritional guidance, community support and premium instructional content. Using a unique, virtual-first care model to help patients find the best path forward, Vori Health connects patients to a trained care team that includes a board-certified, non-operative physical medicine physician, a health coach navigator, and a physical therapist who collaboratively manage the initial patient assessment and coordinate all aspects of care. Learn more at www.vorihealth.com. The company was founded in 2020 and is headquartered in New York, NY.
Spiras Health is an operator of a healthcare organization designed to bring specialized treatment to a patient's home who is coping with a challenging chronic condition. Clinical services provided by their business are provided at clients' homes by a multidisciplinary team of clinicians. These services are enhanced by telehealth, two-way digital communications, and remote patient monitoring, which improves patients' quality of life and reduces the cost of unneeded hospitalizations. The company's mission is to add value by providing compassionate specialized care to patients in their homes.
Stablix Therapeutics is a biotechnology company pioneering the field of Targeted Protein Stabilization (TPS). The company’s resorted platform generates heterobifunctional small molecules (RESTORACS) that recruit deubiquitinase enzymes to remove ubiquitin from targeted proteins and consequently stabilize or increase target protein levels and activity. Stablix initially is leveraging the platform to develop programs to treat rare diseases, cancer, and immunological disorders.
Aetion delivers real-world evidence (RWE) and outcomes-based analytics solutions to life sciences companies, payers, and at-risk providers. With its patented rapid-cycle analytics technology, the Aetion Evidence Platform utilizes the everyday clinical and financial interactions of the healthcare system to unlock essential evidence about the effectiveness and value of medical treatments. Founded by Harvard Medical School faculty members and top big data technologists, Aetion enables payers and providers to collaborate with biopharmaceutical and medical device companies in real-time to develop therapeutic insights and make smart choices in inpatient care. Aetion is based in New York City and backed by investors including New Enterprise Associates (NEA), Flare Capital Partners, Lakestar, Greenspring Associates, Town Hall Ventures, McKesson Ventures, Sanofi Ventures, EDBI, Amgen Ventures, Johnson & Johnson Innovation — JJDC, Inc., UCB, and Horizon Health Services, Inc.
Vori Health offers a new care delivery model for treating musculoskeletal conditions. Its nationwide, all-inclusive medical practice is evidence-based and uniquely positioned to address a multitude of back, neck, and other joint issues. The organization offers integrated medical and rehabilitation care, physical therapy, prescriptions, imaging and lab ordering, health coaching, nutritional guidance, community support and premium instructional content. Using a unique, virtual-first care model to help patients find the best path forward, Vori Health connects patients to a trained care team that includes a board-certified, non-operative physical medicine physician, a health coach navigator, and a physical therapist who collaboratively manage the initial patient assessment and coordinate all aspects of care. Learn more at www.vorihealth.com. The company was founded in 2020 and is headquartered in New York, NY.
Code Biotherapeutics is a next-generation gene therapy company pioneering the development of targeted non-viral gene therapies to treat serious and life-threatening genetic diseases. Code Bio leverages its novel multivalent synthetic DNA delivery platform, 3DNA, which has been engineered to overcome many of the challenges inherent with viral-based gene therapies such as immunogenicity, size and delivery limitations, re-dosability, and manufacturing complexity. The company is advancing an internal pipeline focused on select rare disease programs as well as establishing partnerships to take forward programs in both rare and prevalent diseases.
Sagimet Biosciences is a clinical-stage biopharmaceutical company focused on developing novel therapeutics to treat important diseases such as the liver disease NASH and specific cancers, with focus on targeting dysfunctional metabolic pathways. The company has unique expertise in FASN biology and has created a pipeline of proprietary FASN inhibitors.
SetPoint Medical is a privately held clinical-stage healthcare company dedicated to treating patients with chronic autoimmune diseases. The company is developing a novel platform designed to stimulate the vagus nerve to activate the inflammatory reflex to produce a systemic immune-restorative effect. SetPoint Medical’s platform technology is designed to offer patients and providers a treatment alternative for rheumatoid arthritis, inflammatory bowel disease and other chronic autoimmune conditions with potentially less risk and cost than drug therapy.
Senti Biosciences is a biotechnology company focused on synthetic biology and gene circuit engineering for therapeutic applications. Senti Bio utilizes a synthetic biology platform named Gene Circuits to develop therapies that offer improved precision and control. These circuits are engineered to selectively eliminate cancer cells while sparing healthy ones, enhancing specificity for target cells, and regulating drug expression post-administration.
NeueHealth is a health care service platform that focuses on improving patient experiences and outcomes through a combination of technology and local healthcare resources. It operates 61 affiliated primary care clinics that deliver both virtual and in-person clinical care to nearly 75,000 unique patients. NeueHealth is part of Bright Health Group, which also offers Medicare and commercial health plan products to approximately 623,000 consumers across 14 states. The company aims to reduce healthcare costs while enhancing access and quality of care by aligning the interests of consumers, providers, and payers. Founded in 2015 and based in Minneapolis, Minnesota, NeueHealth leverages intelligent technology to connect users with healthcare services and providers effectively.
Korro Bio provides an efficient and selective method for RNA editing, leveraging natural processes common to all multi-cellular organisms. Korro Bio was created to lead the field of RNA editing. The company is advancing a proprietary platform designed to selectively edit messenger RNA and recode specific codons to effect changes in protein structure and function across multiple tissues. In 2018,
MBX Biosciences is a biotechnology company that develops therapies to treat rare endocrine diseases where there is inadequate treatment available. It focuses on the discovery, development, and commercialization of first-in-class endocrine therapeutics.
Tempus is a technology company improving precision medicine through the practical application of artificial intelligence in healthcare. Their platform is designed to analyze and interpret clinical and molecular data to help healthcare providers deliver more personalized and effective treatments.
Geron is a biotechnology company that specializes in developing blood cancer treatments for hematologic malignancies. The company's Imetelstat, an investigational first-in-class telomerase inhibitor, harnesses Nobel Prize-winning science in a treatment that may change the underlying course of these diseases. Geron was established in 1990 and is headquartered in Foster City, California.
ERYtech Pharma specializes in the encapsulation of therapeutic molecules and enzymes in red blood cells. It has achieved a major breakthrough in the fields of cancer and enzyme therapy by significantly increasing the therapeutic index of the encapsulated molecule or enzyme.
ChromaCode is a molecular diagnostics company focusing on bioinformatics. It leverages patented mathematical methods and algorithmic enhancements to enrich signal processing from life science instrumentation. The company uses this to extract new information on biochemistry reactions and substantially increase the performance capabilities of today’s gold-standard biochemical assays at a very low cost. ChromaCode was founded in 2012, ChromaCode is headquartered in Carlsbad, California.
NeueHealth is a health care service platform that focuses on improving patient experiences and outcomes through a combination of technology and local healthcare resources. It operates 61 affiliated primary care clinics that deliver both virtual and in-person clinical care to nearly 75,000 unique patients. NeueHealth is part of Bright Health Group, which also offers Medicare and commercial health plan products to approximately 623,000 consumers across 14 states. The company aims to reduce healthcare costs while enhancing access and quality of care by aligning the interests of consumers, providers, and payers. Founded in 2015 and based in Minneapolis, Minnesota, NeueHealth leverages intelligent technology to connect users with healthcare services and providers effectively.
SetPoint Medical is a privately held clinical-stage healthcare company dedicated to treating patients with chronic autoimmune diseases. The company is developing a novel platform designed to stimulate the vagus nerve to activate the inflammatory reflex to produce a systemic immune-restorative effect. SetPoint Medical’s platform technology is designed to offer patients and providers a treatment alternative for rheumatoid arthritis, inflammatory bowel disease and other chronic autoimmune conditions with potentially less risk and cost than drug therapy.
Sagimet Biosciences is a clinical-stage biopharmaceutical company focused on developing novel therapeutics to treat important diseases such as the liver disease NASH and specific cancers, with focus on targeting dysfunctional metabolic pathways. The company has unique expertise in FASN biology and has created a pipeline of proprietary FASN inhibitors.
Tempus is a technology company improving precision medicine through the practical application of artificial intelligence in healthcare. Their platform is designed to analyze and interpret clinical and molecular data to help healthcare providers deliver more personalized and effective treatments.
Barricaid develops a bone-anchored implant that reduces the incidence of reherniation and reoperation in patients with large annular defects. It is designed to prevent reherniation by physically blocking the annulus at the post-surgery defect. The anchor component is comprised of titanium alloy that is placed into either the caudal or cranial-adjacent vertebral body to secure the device in position.
Aetion delivers real-world evidence (RWE) and outcomes-based analytics solutions to life sciences companies, payers, and at-risk providers. With its patented rapid-cycle analytics technology, the Aetion Evidence Platform utilizes the everyday clinical and financial interactions of the healthcare system to unlock essential evidence about the effectiveness and value of medical treatments. Founded by Harvard Medical School faculty members and top big data technologists, Aetion enables payers and providers to collaborate with biopharmaceutical and medical device companies in real-time to develop therapeutic insights and make smart choices in inpatient care. Aetion is based in New York City and backed by investors including New Enterprise Associates (NEA), Flare Capital Partners, Lakestar, Greenspring Associates, Town Hall Ventures, McKesson Ventures, Sanofi Ventures, EDBI, Amgen Ventures, Johnson & Johnson Innovation — JJDC, Inc., UCB, and Horizon Health Services, Inc.
Tiburio Therapeutics is a developer of drug compounds intended to treat tumors and endocrine diseases.The company's compounds aid in the treatment of non-functioning pituitary adenoma using a dopamine-somatostatin chimeric molecule that has the potential to shrink or halt tumor growth, providing patients with effective treatment for rare neuroendocrine tumors and endocrine diseases.
Xenon Pharmaceuticals is a biopharmaceutical company focused on the development of novel medicines through the application of our proprietary discovery platform, which we refer to as Extreme Genetics. Our product candidates are based on genetic insights derived from our research of families where individuals exhibit severe traits or phenotypes. They apply their expertise to predict which phenotypes are caused by single-gene defects. By identifying and characterizing the single-gene defects responsible for such severe phenotypes, they gain valuable insights into their function in human biology and their potential as drug targets. Given that these targets are often involved in diseases beyond the rare genetic disorders in which they are first identified, they are developing proprietary product candidates to treat both orphans as well as more prevalent diseases
Curzion Pharmaceuticals
Venture Round in 2019
Curzion Pharmaceuticals is a privately held development-stage biopharma company, and its development-stage oral selective lysophosphatidic acid 1 receptor (LPAR1) antagonist, CZN001 (renamed HZN-825).
NeueHealth is a health care service platform that focuses on improving patient experiences and outcomes through a combination of technology and local healthcare resources. It operates 61 affiliated primary care clinics that deliver both virtual and in-person clinical care to nearly 75,000 unique patients. NeueHealth is part of Bright Health Group, which also offers Medicare and commercial health plan products to approximately 623,000 consumers across 14 states. The company aims to reduce healthcare costs while enhancing access and quality of care by aligning the interests of consumers, providers, and payers. Founded in 2015 and based in Minneapolis, Minnesota, NeueHealth leverages intelligent technology to connect users with healthcare services and providers effectively.
Tempus is a technology company improving precision medicine through the practical application of artificial intelligence in healthcare. Their platform is designed to analyze and interpret clinical and molecular data to help healthcare providers deliver more personalized and effective treatments.
MORE Health delivers access to the best physicians in the world via its cloud-based medical collaboration platform. Hope Lewis was inspired to found MORE Health after several clients suffering from a variety of medical conditions approached her to help them find the most effective treatments possible. Initially delivered as a concierge service to private clients worldwide, MORE Health now also delivers this service to U.S. companies as an employer-provided supplemental health benefit. In the event a serious medical issue arises, their employees can access the extraordinary level of care offered by their Physician Specialists with a Co-Diagnosis or Independent Second Opinion. MORE Health’s mission is to offer you and your family access to the best medical minds in the world, exactly at the moment you need their experience; when you are faced with decisions regarding a serious, life-changing illness. Their vision is to become the virtual global hospital for serious illness, by providing the highest quality of diagnosis and treatment.
MEI Pharma is a oncology company focused on the clinical development of novel therapies for cancer. The Company’s clinical development pipeline includes lead drug candidate Pracinostat, a potential best-in-class, oral histone deacetylase (HDAC) inhibitor. Pracinostat has been tested in more than 150 patients in multiple Phase I and exploratory Phase II clinical trials, including advanced hematologic malignancies such as myelodysplastic syndrome, acute myeloid leukemia and myelofibrosis. The Company expects to initiate a randomized Phase II trial of Pracinostat in combination with standard-of-care in at least one hematologic malignancy toward the middle of 2013. In addition, MEI Pharma is developing two drug candidates derived from its isoflavone-based technology platform, ME-143 and ME-344. Results from a Phase I trial of intravenous ME-143 in heavily treated patients with solid refractory tumors were presented at the American Society of Clinical Oncology Annual Meeting in June 2012. A Phase I clinical trial of intravenous ME-344 in patients with solid refractory tumors is ongoing.
Aetion delivers real-world evidence (RWE) and outcomes-based analytics solutions to life sciences companies, payers, and at-risk providers. With its patented rapid-cycle analytics technology, the Aetion Evidence Platform utilizes the everyday clinical and financial interactions of the healthcare system to unlock essential evidence about the effectiveness and value of medical treatments. Founded by Harvard Medical School faculty members and top big data technologists, Aetion enables payers and providers to collaborate with biopharmaceutical and medical device companies in real-time to develop therapeutic insights and make smart choices in inpatient care. Aetion is based in New York City and backed by investors including New Enterprise Associates (NEA), Flare Capital Partners, Lakestar, Greenspring Associates, Town Hall Ventures, McKesson Ventures, Sanofi Ventures, EDBI, Amgen Ventures, Johnson & Johnson Innovation — JJDC, Inc., UCB, and Horizon Health Services, Inc.
Tempus is a technology company improving precision medicine through the practical application of artificial intelligence in healthcare. Their platform is designed to analyze and interpret clinical and molecular data to help healthcare providers deliver more personalized and effective treatments.
MORE Health delivers access to the best physicians in the world via its cloud-based medical collaboration platform. Hope Lewis was inspired to found MORE Health after several clients suffering from a variety of medical conditions approached her to help them find the most effective treatments possible. Initially delivered as a concierge service to private clients worldwide, MORE Health now also delivers this service to U.S. companies as an employer-provided supplemental health benefit. In the event a serious medical issue arises, their employees can access the extraordinary level of care offered by their Physician Specialists with a Co-Diagnosis or Independent Second Opinion. MORE Health’s mission is to offer you and your family access to the best medical minds in the world, exactly at the moment you need their experience; when you are faced with decisions regarding a serious, life-changing illness. Their vision is to become the virtual global hospital for serious illness, by providing the highest quality of diagnosis and treatment.
Radiology Partners Holdings, LLC, founded in 2012 and headquartered in Manhattan Beach, California, operates within the healthcare sector as a radiology practice center. The company is dedicated to transforming the way radiologists deliver services, catering to hospitals, referring physicians, and patients. By focusing on enhancing the efficiency and effectiveness of radiology services, Radiology Partners aims to improve patient care and support healthcare facilities in meeting their diagnostic needs.
Senti Biosciences is a biotechnology company focused on synthetic biology and gene circuit engineering for therapeutic applications. Senti Bio utilizes a synthetic biology platform named Gene Circuits to develop therapies that offer improved precision and control. These circuits are engineered to selectively eliminate cancer cells while sparing healthy ones, enhancing specificity for target cells, and regulating drug expression post-administration.
FIRE1 and is based in Dublin, Ireland, will focus on developing novel therapeutic devices.
Korro Bio provides an efficient and selective method for RNA editing, leveraging natural processes common to all multi-cellular organisms. Korro Bio was created to lead the field of RNA editing. The company is advancing a proprietary platform designed to selectively edit messenger RNA and recode specific codons to effect changes in protein structure and function across multiple tissues. In 2018,
Tempus is a technology company improving precision medicine through the practical application of artificial intelligence in healthcare. Their platform is designed to analyze and interpret clinical and molecular data to help healthcare providers deliver more personalized and effective treatments.
SetPoint Medical is a privately held clinical-stage healthcare company dedicated to treating patients with chronic autoimmune diseases. The company is developing a novel platform designed to stimulate the vagus nerve to activate the inflammatory reflex to produce a systemic immune-restorative effect. SetPoint Medical’s platform technology is designed to offer patients and providers a treatment alternative for rheumatoid arthritis, inflammatory bowel disease and other chronic autoimmune conditions with potentially less risk and cost than drug therapy.
NeueHealth is a health care service platform that focuses on improving patient experiences and outcomes through a combination of technology and local healthcare resources. It operates 61 affiliated primary care clinics that deliver both virtual and in-person clinical care to nearly 75,000 unique patients. NeueHealth is part of Bright Health Group, which also offers Medicare and commercial health plan products to approximately 623,000 consumers across 14 states. The company aims to reduce healthcare costs while enhancing access and quality of care by aligning the interests of consumers, providers, and payers. Founded in 2015 and based in Minneapolis, Minnesota, NeueHealth leverages intelligent technology to connect users with healthcare services and providers effectively.
Synlogic is a biotechnology company that develops synthetic biotic medicines to perform metabolic functions to treat diseases. The company's lead programs target patients with rare genetic metabolic diseases, including phenylketonuria and secondary hyperoxaluria. Synlogic is also hard at work on synthetic biotics to address more prevalent conditions, including inflammatory bowel disease, cancer, and other metabolic conditions.
Barricaid develops a bone-anchored implant that reduces the incidence of reherniation and reoperation in patients with large annular defects. It is designed to prevent reherniation by physically blocking the annulus at the post-surgery defect. The anchor component is comprised of titanium alloy that is placed into either the caudal or cranial-adjacent vertebral body to secure the device in position.
Radiology Partners Holdings, LLC, founded in 2012 and headquartered in Manhattan Beach, California, operates within the healthcare sector as a radiology practice center. The company is dedicated to transforming the way radiologists deliver services, catering to hospitals, referring physicians, and patients. By focusing on enhancing the efficiency and effectiveness of radiology services, Radiology Partners aims to improve patient care and support healthcare facilities in meeting their diagnostic needs.
EPIX Therapeutics develops and manufactures products for use in electrophysiology based on microwave radiometry technology. Its products provide real-time feedback of energy delivered by catheters during cardiac ablation procedures. The company has a strategic relationship with Hansen Medical Inc. Advanced Cardiac Therapeutics, Inc. (ACT), a medical device company that designs and manufactures a catheter-based system for the treatment of patients with atrial fibrillation (AFIB), today announced it has changed its name to EPIX Therapeutics, Inc.
ChromaCode is a molecular diagnostics company focusing on bioinformatics. It leverages patented mathematical methods and algorithmic enhancements to enrich signal processing from life science instrumentation. The company uses this to extract new information on biochemistry reactions and substantially increase the performance capabilities of today’s gold-standard biochemical assays at a very low cost. ChromaCode was founded in 2012, ChromaCode is headquartered in Carlsbad, California.
SetPoint Medical is a privately held clinical-stage healthcare company dedicated to treating patients with chronic autoimmune diseases. The company is developing a novel platform designed to stimulate the vagus nerve to activate the inflammatory reflex to produce a systemic immune-restorative effect. SetPoint Medical’s platform technology is designed to offer patients and providers a treatment alternative for rheumatoid arthritis, inflammatory bowel disease and other chronic autoimmune conditions with potentially less risk and cost than drug therapy.
Immunomedics is a biopharmaceutical company that specializes in developing monoclonal antibody-based products for the treatment of cancer and other serious diseases. Its corporate objective is to become a fully-integrated biopharmaceutical company. The company was founded in 1982 and headquartered in Morris Plains, New Jersey.
Trillium Therapeutics Inc. operates as a biopharmaceutical research and development company. It focuses on the immune system and its regulation. The company specializes in the discovery and development of protein therapeutics, such as monoclonal antibodies, secreted proteins, and peptides. It involves in therapeutic areas, including autoimmune disease, cancer, necrotizing enterocolitis, and transplantation. Trillium Therapeutics Inc. was formerly known as Transplantation Technologies Inc. and changed its name in May 2003. The company was founded in 1996 and is based in Toronto, Canada.
Cleave Therapeutics develops oncology pharmaceuticals designed to target neurodengeneration and pathways used by cancer cells to grow. The company is engaged in the discovery of novel, small-molecule drugs that affect protein-degradation pathways, upon which cancer cells depend for survival, enabling patients to get cured from cancer.
Docent Health's mission is to help health systems build and retain lasting patient relationships. We are combining best practices from other industries to help health systems deliver the vision of customer-centric care by combining cutting edge consumer technology, retail based strategic marketing, and hospitality inspired service excellence with deep provider experience to increase customer lifetime value and grow market share.
AVEO is a late-stage biopharmaceutical company focused on the discovery and development of targeted cancer therapeutics. AVEO's proprietary, integrated cancer biology platform enables the company to pursue highly efficient drug development strategies in oncology that increase the probability of clinical success and provides a discovery engine for high-value targets and therapies. This approach has resulted in a balanced pipeline of novel cancer therapies focused on well-validated targets (VEGFR, EGFR) and promising novel targets (HGF, FGFR, ErbB3 and NOTCH), as well as collaborations with Eli Lilly, Merck, OSI Pharmaceuticals, Schering-Plough, and Biogen Idec. The company was established in 2001 and is based in Cambridge, Massachusetts.
FIRE1 and is based in Dublin, Ireland, will focus on developing novel therapeutic devices.
LinkDoc offer private hospital deployed in line with the US HIPAA Act standards. Coupled with the financial level security solutions to protect patient privacy and data without fear.
NeueHealth is a health care service platform that focuses on improving patient experiences and outcomes through a combination of technology and local healthcare resources. It operates 61 affiliated primary care clinics that deliver both virtual and in-person clinical care to nearly 75,000 unique patients. NeueHealth is part of Bright Health Group, which also offers Medicare and commercial health plan products to approximately 623,000 consumers across 14 states. The company aims to reduce healthcare costs while enhancing access and quality of care by aligning the interests of consumers, providers, and payers. Founded in 2015 and based in Minneapolis, Minnesota, NeueHealth leverages intelligent technology to connect users with healthcare services and providers effectively.
Founded in 2010, TESARO is a privately held oncology-focused biopharmaceutical company dedicated to improving the lives of cancer patients. The Company intends to leverage the experience and competencies of its management team to identify, acquire and develop promising drug candidates; and to commercialize safer and more effective products for the treatment and support of cancer patients. TESARO is developing rolapitant, a potent, selective neurokinin-1 receptor antagonist that has completed Phase 2 clinical testing for the prevention of chemotherapy induced nausea and vomiting, and is advancing its ALK inhibitor program for oncology indications. Phase 3 clinical testing of rolapitant is planned to commence during 2011 and the first ALK inhibitor clinical trial is targeted to begin in 2012. TESARO was co-founded by former executives of MGI PHARMA, an oncology and acute-care focused biopharmaceutical company that Eisai Co., Ltd. acquired in 2008 for $3.9 billion. TESARO is headquartered in Waltham, Massachusetts.
Synlogic is a biotechnology company that develops synthetic biotic medicines to perform metabolic functions to treat diseases. The company's lead programs target patients with rare genetic metabolic diseases, including phenylketonuria and secondary hyperoxaluria. Synlogic is also hard at work on synthetic biotics to address more prevalent conditions, including inflammatory bowel disease, cancer, and other metabolic conditions.
AVEO is a late-stage biopharmaceutical company focused on the discovery and development of targeted cancer therapeutics. AVEO's proprietary, integrated cancer biology platform enables the company to pursue highly efficient drug development strategies in oncology that increase the probability of clinical success and provides a discovery engine for high-value targets and therapies. This approach has resulted in a balanced pipeline of novel cancer therapies focused on well-validated targets (VEGFR, EGFR) and promising novel targets (HGF, FGFR, ErbB3 and NOTCH), as well as collaborations with Eli Lilly, Merck, OSI Pharmaceuticals, Schering-Plough, and Biogen Idec. The company was established in 2001 and is based in Cambridge, Massachusetts.
Cascadian Therapeutics, a clinical-stage biopharmaceutical company, researches and develops, and sells therapeutic products for the treatment of cancer in the United States. The company lead clinical-stage product candidate is tucatinib, an orally active and HER2-selective small molecule tyrosine kinase inhibitor, which is in two Phase Ib trials, one in combination with Kadcyla and another in combination with Xeloda and/or Herceptin. It is also developing Checkpoint kinase 1, a protein kinase that is in pre-clinical studies to regulate the cell division cycle, as well as to DNA damage and replication stress. In addition, the company focuses on the development of novel antibodies and T-cell immunoreceptor with Ig and ITM domains, an inhibitory receptor expressed on T-cells and NK cells that negatively regulate immune response to cancers. It has a license agreement with Array BioPharma Inc. to develop, manufacture and commercialize tucatinib; research collaboration agreement with Sentinel Oncology Ltd. for the discovery of novel Chk1 inhibitors; and collaboration agreement with Adimab LLC for the discovery of novel antibodies against d immunotherapy targets in oncology.
23andMe is a human genome research company enabling users to study their ancestry, genealogy, and inherited traits. A startup co-founded by Linda Avey and Anne Wojcicki, the wife of Google co-founder Sergey Brin, 23andMe has plans to make the human genome searchable. Brin, along with Google, gave 23andMe $3.9 million as part of a series A in May of 2007. The company was named after the number of chromosome pairs in humans. They aim to help people understand what their genes mean by indexing them and highlighting significant findings. 23andMe allows its clients/users to study their ancestry, genealogy and inherited traits. The company also markets to researchers and scientists, for whom they provide neatly categorized and easily searchable data. One reason the Google investment in 23andMe made sense was that this company could enable the search giant to index another facet of the world's information. With the Biotech and Health Care industries growing rapidly, 23andMe could help Google get and maintain a market hold in these already multi-billion dollar areas.
Proteostasis Therapeutics is discovering and developing novel small molecule therapeutics designed to control the body's protein homeostasis, or Proteostasis Network. The Proteostasis Network maintains the body's natural balance of proteins to protect us from numerous diseases. These novel therapies, or Proteostasis Regulators, are designed to treat multiple genetic and degenerative disorders associated with deficiencies of the Proteostasis Network, such as emphysema, type II diabetes, Alzheimer's Disease and Huntington's Disease.
Ra Pharma is developing Cyclomimetics, a new drug class with the diversity and specificity of antibodies, coupled with the many benefits of small molecules. Ra Pharma is leveraging its ability to rapidly generate drug candidates to develop its own portfolio of products and partnerships focused on intracellular protein-protein interactions and other innovative approaches to addressing unmet medical needs. It was founded in 2008 and headquartered in Cambridge, Massachusetts.
MEDIAN Technologies develops medical imaging software and services dedicated to oncology clinical trials, cancer screening, and clinical practice. The company standardizes and automates the interpretation of medical images in oncology to optimize the diagnosis of cancer patients and the assessment of their response to therapy. The company serves two primary markets: drug development and patient care. MEDIAN Technologies has a strategic partnership with a contract research organization to offer integrated imaging services for clinical trials to biopharma sponsors worldwide, and a strategic partnership with Canon to develop new imaging technologies, and to address the patient care market. MEDIAN Technologies was founded in 2002 and is based in Sophia-Antipolis, France.
XTuit Pharmaceuticals develops pharmaceutical preparations for use in the diagnosis and treatment of oncological, tumor, and inflammatory diseases. The company is pursuing novel approaches to improving cancer therapy by targeting the tumor microenvironment. It was incorporated in 2011 and is based in Waltham, Massachusetts.
MORE Health delivers access to the best physicians in the world via its cloud-based medical collaboration platform. Hope Lewis was inspired to found MORE Health after several clients suffering from a variety of medical conditions approached her to help them find the most effective treatments possible. Initially delivered as a concierge service to private clients worldwide, MORE Health now also delivers this service to U.S. companies as an employer-provided supplemental health benefit. In the event a serious medical issue arises, their employees can access the extraordinary level of care offered by their Physician Specialists with a Co-Diagnosis or Independent Second Opinion. MORE Health’s mission is to offer you and your family access to the best medical minds in the world, exactly at the moment you need their experience; when you are faced with decisions regarding a serious, life-changing illness. Their vision is to become the virtual global hospital for serious illness, by providing the highest quality of diagnosis and treatment.
CRISPR Therapeutics is focused on the development of transformative medicines using its proprietary CRISPR/Cas9 gene-editing platform. CRISPR/Cas9 is a revolutionary technology that allows for precise, directed changes to genomic DNA. They have licensed the foundational CRISPR/Cas9 patent estate for human therapeutic use from their scientific founder, Dr. Emmanuelle Charpentier, who co-invented the application of CRISPR/Cas9 for gene editing. CRISPR Therapeutics’ vision is to cure serious human diseases at the molecular level using CRISPR-Cas9. The company is headquartered in Basel, Switzerland and has operations in London, UK.
Mirna Therapeutics, Inc. (Mirna) is a discovery-stage biopharmaceutical research and development company focused on miRNA-directed human oncology therapies. Featuring world-class research capabilities, a strong understanding of miRNA and cancer biology, and an expansive IP portfolio, Mirna Therapeutics is well-positioned to capitalize on the emerging field of miRNA-based therapeutics.
CRISPR Therapeutics is focused on the development of transformative medicines using its proprietary CRISPR/Cas9 gene-editing platform. CRISPR/Cas9 is a revolutionary technology that allows for precise, directed changes to genomic DNA. They have licensed the foundational CRISPR/Cas9 patent estate for human therapeutic use from their scientific founder, Dr. Emmanuelle Charpentier, who co-invented the application of CRISPR/Cas9 for gene editing. CRISPR Therapeutics’ vision is to cure serious human diseases at the molecular level using CRISPR-Cas9. The company is headquartered in Basel, Switzerland and has operations in London, UK.
Champions Oncology was founded by some of the world’s most renowned specialists in the field of cancer diagnosis, treatment, and research. Our team is comprised of seasoned oncology professionals passionately dedicated to working with you to accelerate oncology drug development, improve outcomes and extend lives. Our core platform, the Champions TumorGraft™ offers an enhanced xenograft mouse avatar model for growing and testing human tumors.