Panakes Fund I

Vivasure Medical Limited, a medical device company, engages in the research, development, and manufacture of arterial and venous closure devices based on its patented PerQseal technology. The company develops polymer implants and delivery systems that primarily focused on minimally invasive vessel closures in cardiology, interventional radiology, and vascular surgery areas. Its lead product is an absorbable patch-based large-bore percutaneous closure device that is designed to enable closure of large arteriotomies in transcatheter procedures, such as those used for transcatheter aortic valve replacement (TAVR) and endovascular aneurysm repair (EVAR). Vivasure Medical Limited was incorporated in 2008 and is based in Galway, Ireland.

Seventeen is a medtech startup. The company intends to use the funds to finalize the technology and clinically validate it in order to obtain the CE mark.

MMI S.r.l manufactures and develops micro instruments to support surgical interventions at a dimensional scale. The company develops wristed micro instruments and their fabrication process. The company also develops and offers robotic platform. The company's proprietary robotic platform and wristed micro instruments simplifies reconstruction procedures after traumatic injuries and after tumor removal in breast, head, and bones. The company was founded in 2015 and is headquartered in Calci, Italy.

Endostart is a developed a novel proprietary Magnetic Balloon Anchoring Technology.

Echolight S.r.l., a research based biomed company, develops a non-invasive solution for early diagnosis of osteoporosis. It offers EchoS, an ultrasound device for bone characterization with an approach assessing bone micro-architecture that enables the scanning of central sites. The company was founded in 2011 and is based in Lecce, Italy.

The company intends to use the funds to accelerate the development of its platform of topical non-steroidal treatments for atopic dermatitis both in children and adults, as well as other types of dermatological disorders.

SamanTree Medical SA, a medical microscopy device company, develops micro-optics based digital microscopy systems with XXL field of view for research, diagnostic, and surgical applications. The company develops a surgical digital microscope that precisely assesses tumor margins by visualizing the cellular structure of the living tissue in real time. Its digital microscope improves surgical treatment decisions and resection accuracy, while reducing the re-operation rates and cutting the overall cost of procedures. The company was incorporated in 2014 and is based in Ecublens, Switzerland.

Alesi Surgical was founded in 2009 to develop and commercialise products that improve the safety, efficacy and outcomes of surgical procedures. The company is a spin-out from the Welsh Institute for Minimal Access Therapy (WIMAT), a leading surgical training centre in the UK. Alesi Surgical has a unique level of access to experienced surgeons, surgical trainers and trainees, which allows it to identify issues in procedures and design devices to address these issues.

MMI S.r.l manufactures and develops micro instruments to support surgical interventions at a dimensional scale. The company develops wristed micro instruments and their fabrication process. The company also develops and offers robotic platform. The company's proprietary robotic platform and wristed micro instruments simplifies reconstruction procedures after traumatic injuries and after tumor removal in breast, head, and bones. The company was founded in 2015 and is headquartered in Calci, Italy.

Enterprise Therapeutics is a drug discovery company dedicated to the research and development of novel therapies for the treatment of respiratory diseases. In diseases such as cystic fibrosis, asthma and COPD the lungs become congested with mucus leading to difficulty in breathing. New disease modifying therapies that target the underlying mechanisms of mucus congestion will reduce the frequency of lung infections and improve patient quality of life.

Allotex, Inc., an ophthalmic biologics and device company, develops contact lens. The company develops allograft corneal inlays and onlays that address all the refractive needs. It develops therapeutic solutions for the treatment of presbyopia, hyperopia, and myopia. The company was incorporated in 2013 and is based in Boston, Massachusetts.

EBAMed SA is a Swiss startup based in Geneva whose mission is to enable safe and effective non-invasive treatments of heart arrhythmias with protontherapy. The company is currently developing a medical device to enable non-invasive heart motion imaging and real-time synchronization of the therapeutic beam. This device consists in both hardware and software components and expands treatment possibilities for existing protontherapy centres, enabling them for the first time to treat heart patients.

CARTHERA SAS designs and develops therapeutic ultrasound-based medical devices for treating brain disorders. The company’s devices include SONOPROBE, which is used for treatment of brain disorders including brain tumors, epilepsy, metastases, and meningioma and SONOCLOUD, an intracranial ultrasound implant that is used to increase the intracerebral bioavailability of chemotherapy in the treatment of primary brain tumors. The company was founded in 2010 and is headquartered in Paris, France.

MMI S.r.l manufactures and develops micro instruments to support surgical interventions at a dimensional scale. The company develops wristed micro instruments and their fabrication process. The company also develops and offers robotic platform. The company's proprietary robotic platform and wristed micro instruments simplifies reconstruction procedures after traumatic injuries and after tumor removal in breast, head, and bones. The company was founded in 2015 and is headquartered in Calci, Italy.

Vivasure Medical Limited, a medical device company, engages in the research, development, and manufacture of arterial and venous closure devices based on its patented PerQseal technology. The company develops polymer implants and delivery systems that primarily focused on minimally invasive vessel closures in cardiology, interventional radiology, and vascular surgery areas. Its lead product is an absorbable patch-based large-bore percutaneous closure device that is designed to enable closure of large arteriotomies in transcatheter procedures, such as those used for transcatheter aortic valve replacement (TAVR) and endovascular aneurysm repair (EVAR). Vivasure Medical Limited was incorporated in 2008 and is based in Galway, Ireland.

Diadem Srl engages in the drug development for Alzheimer’s disease. The company was founded in 2012 and is based in Brescia, Italy.

InnovHeart s.r.l. manufactures transcatheter mitral valve replacement (TMVR) systems for the treatment of mitral valve disease. The company offers Saturn TMVR system a mitral heart valve designed for trans-apical or trans-septal delivery systems. InnovHeart s.r.l. was founded in 2015 and is based in Milan, Italy with an additional office in Newton, Massachusetts.

CARTHERA SAS designs and develops therapeutic ultrasound-based medical devices for treating brain disorders. The company’s devices include SONOPROBE, which is used for treatment of brain disorders including brain tumors, epilepsy, metastases, and meningioma and SONOCLOUD, an intracranial ultrasound implant that is used to increase the intracerebral bioavailability of chemotherapy in the treatment of primary brain tumors. The company was founded in 2010 and is headquartered in Paris, France.

Neuromod Devices Limited, a medical device company, specializes in the research and development of neuromodulation treatments for chronic tinnitus. Its mutebutton is a bi-modal neuromodulation device that focuses on promoting positive therapeutic change in the human nervous system. The company was founded in 2010 and is based in Dublin, Ireland.

Nouscom are a well established team that has worked together for many years in previous successful enterprises, including IRBM/Merck and Okairos, and are veterans in the field of oncolytic and genetic vaccines. The company is headquartered in Basel, Switzerland and has operations in Rome, Italy. The NousCom team is lead by experienced enterpreneurs that worked together for many years in previous successful enterprises, such as Okairos, under the leadership of Prof. Riccardo Cortese, who conceived the ideas behind those companies.

SamanTree Medical SA, a medical microscopy device company, develops micro-optics based digital microscopy systems with XXL field of view for research, diagnostic, and surgical applications. The company develops a surgical digital microscope that precisely assesses tumor margins by visualizing the cellular structure of the living tissue in real time. Its digital microscope improves surgical treatment decisions and resection accuracy, while reducing the re-operation rates and cutting the overall cost of procedures. The company was incorporated in 2014 and is based in Ecublens, Switzerland.

InnovHeart s.r.l. manufactures transcatheter mitral valve replacement (TMVR) systems for the treatment of mitral valve disease. The company offers Saturn TMVR system a mitral heart valve designed for trans-apical or trans-septal delivery systems. InnovHeart s.r.l. was founded in 2015 and is based in Milan, Italy with an additional office in Newton, Massachusetts.

Complement Therapeutics operates as a preclinical stage company. Complement Therapeutics develops a precision medicine diagnostic platform allowing it to stratify patients based on their complement-activation profile with the potential to enable both patient selection and serving as an efficacy biomarker in future clinical studies.

Salvia is a young innovative start-up company active in the emerging field of “BioElectronics” that is inspired by biology and electronics to provide innovative therapeutic solutions. The name Salvia is derived from the Latin word salvere, which means "to stay healthy".​They are driven to deliver bioelectronic solutions that restore health for people suffering from severe neurologic disorders; their ambition is to make these novel therapies widely accessible. The Salvia team consists of experienced entrepreneurs, engineers and scientists with diverse professional backgrounds and proven track-record throughout the medical device industry (Sapiens, Medtronic, Philips, St Jude, BioSensors International, Kyphon, etc).