PTV Healthcare Capital

PTV is a healthcare venture capital firm dedicated to enabling healthcare entrepreneurs and global innovation. It is comprised of a highly collaborative team of professionals, deeply experienced as investors and operators of life science companies. PTV focuses on mid-to-late stage companies with comparatively low technical, regulatory, and financial risk that are “with the grain” of healthcare economics – improving patient outcomes while decreasing costs – in markets with significant unmet clinical needs.

Matt Crawford

Founding Managing Director

Clay Samford

Senior Associate

34 past transactions

Cardiva Medical

Debt Financing in 2018
Cardiva Medical is a medical device company that’s focused on developing and commercializing innovative vascular closure technology designed to help the body heal itself following catheterization. The company’s products include VASCADE, a vascular closure system, and Catalyst II and Catalyst III, which are designed to aid manual compression. It was founded in 2002 and headquartered in Sunnyvale, California.

Intuity Medical

Debt Financing in 2018
Intuity Medical develops blood glucose monitoring systems for diabetes management. Their POGO Automatic Blood Glucose Monitoring System is the world’s first FDA-cleared automatic, one-step blood glucose meter that combines lancing, blood collection, and analysis into a single 10-test cartridge. It provides a convenient and discreet solution for millions of patients who need to regularly test their blood glucose. The company was founded in 2002 and is headquartered in Fremont, California.

Cardiva Medical

Venture Round in 2017
Cardiva Medical is a medical device company that’s focused on developing and commercializing innovative vascular closure technology designed to help the body heal itself following catheterization. The company’s products include VASCADE, a vascular closure system, and Catalyst II and Catalyst III, which are designed to aid manual compression. It was founded in 2002 and headquartered in Sunnyvale, California.

Intuity Medical

Venture Round in 2016
Intuity Medical develops blood glucose monitoring systems for diabetes management. Their POGO Automatic Blood Glucose Monitoring System is the world’s first FDA-cleared automatic, one-step blood glucose meter that combines lancing, blood collection, and analysis into a single 10-test cartridge. It provides a convenient and discreet solution for millions of patients who need to regularly test their blood glucose. The company was founded in 2002 and is headquartered in Fremont, California.

Apollo Endosurgery

Convertible Note in 2015
Apollo Endosurgery develops medical devices for the diagnosis and treatment of gastrointestinal diseases. The company’s device-based therapies are an alternative to invasive surgical procedures, thus lowering complication rates and reducing total healthcare costs. Apollo’s products include the X-Tack™ Endoscopic HeliX Tacking System, the OverStitch™ Endoscopic Suturing System, the OverStitch Sx™ Endoscopic Suturing System, and the ORBERA® Intragastric Balloon. Apollo Endosurgery was founded upon the initial work of the Apollo Group, an international think tank of world-renowned gastroenterologists and surgeons from five leading universities (Mayo Clinic, Johns Hopkins, Medical University of South Carolina, University of Texas Medical Branch-Galveston and Chinese University-Hong Kong.) Disappointed with the pace of innovation in therapeutic flexible endoscopy, the Group assembled in 1998 (Timeline) with the goal to advance the new discipline; their specific focus was the use of long, flexible instruments deployed through a natural orifice in order to diagnose and potentially treat gastrointestinal disorders.

Cardiva Medical

Venture Round in 2014
Cardiva Medical is a medical device company that’s focused on developing and commercializing innovative vascular closure technology designed to help the body heal itself following catheterization. The company’s products include VASCADE, a vascular closure system, and Catalyst II and Catalyst III, which are designed to aid manual compression. It was founded in 2002 and headquartered in Sunnyvale, California.

Intersect ENT

Series D in 2013
Intersect ENT Inc. (formerly Sinexus) is a medical device company pioneering novel therapies for Ear, Nose, and Throat surgeons to utilize in providing improved treatment for their patients. The company was founded in 2003 by Don Eaton and is headquartered in Menlo Park, California, United States.

Tryton Medical

Venture Round in 2013
Tryton Medical, Inc. develops stent systems for the treatment of cardiovascular diseases in the United States, Austria, Belgium, Denmark, Ireland, Luxembourg, the Netherlands, Norway, Poland, Portugal, Spain, and the United Kingdom. It offers the Tryton Side Branch Stent System, which offers a strategy for treating atherosclerotic lesions in the side branch at the site of a bifurcation. The company was founded in 2003 and is based in Durham, North Carolina.

Mirna Therapeutics

Series C in 2012
Mirna Therapeutics, Inc. (Mirna) is a discovery-stage biopharmaceutical research and development company focused on miRNA-directed human oncology therapies. Featuring world-class research capabilities, a strong understanding of miRNA and cancer biology, and an expansive IP portfolio, Mirna Therapeutics is well-positioned to capitalize on the emerging field of miRNA-based therapeutics.

Cardiva Medical

Venture Round in 2012
Cardiva Medical is a medical device company that’s focused on developing and commercializing innovative vascular closure technology designed to help the body heal itself following catheterization. The company’s products include VASCADE, a vascular closure system, and Catalyst II and Catalyst III, which are designed to aid manual compression. It was founded in 2002 and headquartered in Sunnyvale, California.

Apollo Endosurgery

Series B in 2012
Apollo Endosurgery develops medical devices for the diagnosis and treatment of gastrointestinal diseases. The company’s device-based therapies are an alternative to invasive surgical procedures, thus lowering complication rates and reducing total healthcare costs. Apollo’s products include the X-Tack™ Endoscopic HeliX Tacking System, the OverStitch™ Endoscopic Suturing System, the OverStitch Sx™ Endoscopic Suturing System, and the ORBERA® Intragastric Balloon. Apollo Endosurgery was founded upon the initial work of the Apollo Group, an international think tank of world-renowned gastroenterologists and surgeons from five leading universities (Mayo Clinic, Johns Hopkins, Medical University of South Carolina, University of Texas Medical Branch-Galveston and Chinese University-Hong Kong.) Disappointed with the pace of innovation in therapeutic flexible endoscopy, the Group assembled in 1998 (Timeline) with the goal to advance the new discipline; their specific focus was the use of long, flexible instruments deployed through a natural orifice in order to diagnose and potentially treat gastrointestinal disorders.

Cardiva Medical

Venture Round in 2011
Cardiva Medical is a medical device company that’s focused on developing and commercializing innovative vascular closure technology designed to help the body heal itself following catheterization. The company’s products include VASCADE, a vascular closure system, and Catalyst II and Catalyst III, which are designed to aid manual compression. It was founded in 2002 and headquartered in Sunnyvale, California.

Intersect ENT

Series C in 2010
Intersect ENT Inc. (formerly Sinexus) is a medical device company pioneering novel therapies for Ear, Nose, and Throat surgeons to utilize in providing improved treatment for their patients. The company was founded in 2003 by Don Eaton and is headquartered in Menlo Park, California, United States.

IDEV Technologies

Series D in 2010
IDEV Technologies is an emerging growth medical device company focused on the development of products for endovascular and interventional applications. Currently, IDEV markets SUPERA, a novel self-expanding nitinol stent. Using a patented interwoven design, SUPERA offers improved flexibility, radial strength, and kink and crush resistance compared to other marketed stents. SUPERA is currently approved for use in the treatment of biliary strictures in the US. IDEV is currently enrolling patients in the SUPERB IDE trial to study SUPERA's safety and efficacy when used in the superficial femoral artery (SFA).

Tryton Medical

Series D in 2010
Tryton Medical, Inc. develops stent systems for the treatment of cardiovascular diseases in the United States, Austria, Belgium, Denmark, Ireland, Luxembourg, the Netherlands, Norway, Poland, Portugal, Spain, and the United Kingdom. It offers the Tryton Side Branch Stent System, which offers a strategy for treating atherosclerotic lesions in the side branch at the site of a bifurcation. The company was founded in 2003 and is based in Durham, North Carolina.

Ortho Kinematics

Series A in 2010
Ortho Kinematics is a spine diagnostics company, provides spine motion analysis and diagnostic services. The company provides information to spine clinicians to assist them in diagnosing and treating back and neck pain. Its solution includes KineGraph Vertebral Motion Analyzer, an automated functional diagnostic test for the spine that uses fluoroscopy to capture the spine in motion, producing patient-specific graphs of the kinematics for each vertebral level. The company was founded in 2006 and is based in Austin, Texas.

Ortho Kinematics

Venture Round in 2009
Ortho Kinematics is a spine diagnostics company, provides spine motion analysis and diagnostic services. The company provides information to spine clinicians to assist them in diagnosing and treating back and neck pain. Its solution includes KineGraph Vertebral Motion Analyzer, an automated functional diagnostic test for the spine that uses fluoroscopy to capture the spine in motion, producing patient-specific graphs of the kinematics for each vertebral level. The company was founded in 2006 and is based in Austin, Texas.

Alereon

Venture Round in 2008
Alereon is a fabless semiconductor company developing innovative Ultrawideband (UWB) wireless chipsets. Their mission is to simplify networking by removing cables, allowing effortless connections between PCs, consumer electronics, peripherals and mobile devices. We want to change the way consumers connect to the world.

Cameron Health

Series E in 2008
Cameron Health, Inc., a development stage medical device company, is creating the next generation of implantable electronic device utilizing state-of-the-art technologies. They are a team of specialized, high technology, creative individuals with decades of experience in solving difficult medical problems. Their current target is the development of a family of devices that will afford patient treatment that has been, until now, unattainable with the current therapeutic modalities and technologies.

Intersect ENT

Series B in 2008
Intersect ENT Inc. (formerly Sinexus) is a medical device company pioneering novel therapies for Ear, Nose, and Throat surgeons to utilize in providing improved treatment for their patients. The company was founded in 2003 by Don Eaton and is headquartered in Menlo Park, California, United States.

Cardiva Medical

Series D in 2008
Cardiva Medical is a medical device company that’s focused on developing and commercializing innovative vascular closure technology designed to help the body heal itself following catheterization. The company’s products include VASCADE, a vascular closure system, and Catalyst II and Catalyst III, which are designed to aid manual compression. It was founded in 2002 and headquartered in Sunnyvale, California.

IDEV Technologies

Series C in 2008
IDEV Technologies is an emerging growth medical device company focused on the development of products for endovascular and interventional applications. Currently, IDEV markets SUPERA, a novel self-expanding nitinol stent. Using a patented interwoven design, SUPERA offers improved flexibility, radial strength, and kink and crush resistance compared to other marketed stents. SUPERA is currently approved for use in the treatment of biliary strictures in the US. IDEV is currently enrolling patients in the SUPERB IDE trial to study SUPERA's safety and efficacy when used in the superficial femoral artery (SFA).

Accumetrics

Series D in 2008
Accumetrics is a privately-held company that develops, manufactures, and markets the VerifyNow System, a comprehensive suite of assays for the assessment of platelet function. Accumetrics, based in San Diego, California, was founded in 1996, sold to Radiometer in 2000, and repurchased by company management and investors in 2003.

Asuragen

Series B in 2007
Asuragen is a fully integrated diagnostics company focused on molecular oncology and early detection of cancer, with an emphasis on microRNA. Asuragen's current diagnostics product portfolio consists of Signature® Genetic and Oncology Testing products, as well as industry leading controls and standards engineered using its patented Armored RNA® technology. In addition to its diagnostics products, Asuragen offers GLP testing services and an established cGMP manufacturing facility that allow it to span the spectrum of discovery, testing, production and commercialization.

Apollo Endosurgery

Series A in 2007
Apollo Endosurgery develops medical devices for the diagnosis and treatment of gastrointestinal diseases. The company’s device-based therapies are an alternative to invasive surgical procedures, thus lowering complication rates and reducing total healthcare costs. Apollo’s products include the X-Tack™ Endoscopic HeliX Tacking System, the OverStitch™ Endoscopic Suturing System, the OverStitch Sx™ Endoscopic Suturing System, and the ORBERA® Intragastric Balloon. Apollo Endosurgery was founded upon the initial work of the Apollo Group, an international think tank of world-renowned gastroenterologists and surgeons from five leading universities (Mayo Clinic, Johns Hopkins, Medical University of South Carolina, University of Texas Medical Branch-Galveston and Chinese University-Hong Kong.) Disappointed with the pace of innovation in therapeutic flexible endoscopy, the Group assembled in 1998 (Timeline) with the goal to advance the new discipline; their specific focus was the use of long, flexible instruments deployed through a natural orifice in order to diagnose and potentially treat gastrointestinal disorders.

LDR Holding

Series C in 2007
LDR Holding Corporation develops and markets implantable spine systems and instrumentation for patients and the surgeon community in the United States and internationally. Its spinal surgery solutions include cervical and lumbar artificial disc systems, pedicle screw systems, implant systems, cervical cages, synthetic bone substitutes, and ALIF and TLIF devices, as well as VerteBRIDGE product, a direct lateral and oblique lumbar system for surgical applications. The company offers its products through partnerships with surgeons and distributors in Australia, Argentina, Austria, Belgium, Denmark, Greece, the Netherlands, Italy, Japan, Korea, Mexico, Malaysia, Peru, Portugal, South Africa, Spain, China, Switzerland, Taiwan, Thailand, Turkey, and the United Kingdom. LDR Holding Corporation was formerly known as LDR Spine USA, Inc. and changed its name after acquiring LDR Médical. The company was founded in 2004 and is based in Austin, Texas with additional offices in Troyes, France; Beijing, China; Sao Paolo, Brazil; and Munich, Germany.

Alereon

Series B in 2007
Alereon is a fabless semiconductor company developing innovative Ultrawideband (UWB) wireless chipsets. Their mission is to simplify networking by removing cables, allowing effortless connections between PCs, consumer electronics, peripherals and mobile devices. We want to change the way consumers connect to the world.

On-X Life Technologies

Venture Round in 2007
On-X Life Technologies develops, manufactures, and offers artificial heart valve replacement and repair products. The company’s product portfolio includes Aortic Heart Valve with Standard Sewing Ring, Aortic Heart Valve with Conform-X Sewing Ring, Aortic Heart Valve with Anatomic Sewing Ring, Mitral Heart Valve with Standard Sewing Ring, Mitral Heart Valve with Conform-X Sewing Ring, Ascending Aortic Prosthesis, Chord-XTM ePTFE Suture, CO2 diffusion catheters, and more. On-X Life Technologies was incorporated in 1994 and is based in Austin, Texas.

BioSET

Venture Round in 2007
BioSurface Engineering Technologies, Inc., also known as BioSET, engages in developing proprietary therapeutic peptides as medical devices to improve bone and soft tissue repair. The company focuses on developing devices for orthobiologics applications. Its products include AMPLEX, an implantable combination device of the B2A peptide and a synthetic ceramic scaffold for use as a surgical bone graft implant for lumbar degenerative disc disease, as well as for use in spine, cervical spine, and foot and ankle fusion surgeries. The company also develops products for sports medicine applications based on its F2A peptide; and peptide signaling molecules and various scaffold biomaterials for use in musculoskeletal applications, including trauma, fracture repair, and other soft tissue treatments. BioSurface Engineering Technologies, Inc. was founded in 2001 and is based in Rockville, Maryland.

LDR Holding

Series B in 2006
LDR Holding Corporation develops and markets implantable spine systems and instrumentation for patients and the surgeon community in the United States and internationally. Its spinal surgery solutions include cervical and lumbar artificial disc systems, pedicle screw systems, implant systems, cervical cages, synthetic bone substitutes, and ALIF and TLIF devices, as well as VerteBRIDGE product, a direct lateral and oblique lumbar system for surgical applications. The company offers its products through partnerships with surgeons and distributors in Australia, Argentina, Austria, Belgium, Denmark, Greece, the Netherlands, Italy, Japan, Korea, Mexico, Malaysia, Peru, Portugal, South Africa, Spain, China, Switzerland, Taiwan, Thailand, Turkey, and the United Kingdom. LDR Holding Corporation was formerly known as LDR Spine USA, Inc. and changed its name after acquiring LDR Médical. The company was founded in 2004 and is based in Austin, Texas with additional offices in Troyes, France; Beijing, China; Sao Paolo, Brazil; and Munich, Germany.

Crescent Biopharma

Series B in 2006
GlycoMimetics, Inc., a biopharmaceutical company, engages in the design and development of small molecule therapeutics to mimic the functions of bioactive carbohydrates. Its products include GMI-1070, a synthetic glycomimetic molecule designed to inhibit selectin types, such as E, P, and L-selectin; and GMI-1051, a small molecular weight compound for the treatment or prevention of infections caused by pseudomonas aeruginosa. The company was founded in 2003 and is based in Gaithersburg, Maryland. GlycoMimetics, Inc. acquired by Crescent BioPharma in an Reverse Merger, where GlycoMimetics changed its name to Crescent BioPharma, Inc.

BioMimetic Therapeutics

Series C in 2005
BioMimetic Therapeutics is a biotechnology company that develops products to help stimulate the body natural tissue regenerative process. The company's products and product candidates include Augment Injectable and Augment Rotator Cuff for several orthopedic and sports medicine indications comprising the treatment of foot and ankle fusions, the stimulation of wrist fracture healing, and the surgical treatment of rotator cuff tears, as well as Augment Tendinopathy Injection for injuries cause of tendon overuse. BioMimetic Therapeutics was founded on 1999 and is headquartered in Franklin, Tennessee.

Crescent Biopharma

Series A in 2004
GlycoMimetics, Inc., a biopharmaceutical company, engages in the design and development of small molecule therapeutics to mimic the functions of bioactive carbohydrates. Its products include GMI-1070, a synthetic glycomimetic molecule designed to inhibit selectin types, such as E, P, and L-selectin; and GMI-1051, a small molecular weight compound for the treatment or prevention of infections caused by pseudomonas aeruginosa. The company was founded in 2003 and is based in Gaithersburg, Maryland. GlycoMimetics, Inc. acquired by Crescent BioPharma in an Reverse Merger, where GlycoMimetics changed its name to Crescent BioPharma, Inc.

Alereon

Series A in 2004
Alereon is a fabless semiconductor company developing innovative Ultrawideband (UWB) wireless chipsets. Their mission is to simplify networking by removing cables, allowing effortless connections between PCs, consumer electronics, peripherals and mobile devices. We want to change the way consumers connect to the world.
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