PTV Healthcare Capital

Cardiva Medical, Inc. is a medical device company that specializes in vascular access management products designed to facilitate the body's healing process after catheterization procedures. The company offers several innovative products, including the VASCADE VCS, an extravascular and bioabsorbable femoral access closure system that promotes rapid hemostasis while reducing complications. Additionally, Cardiva Medical provides the Cardiva CATALYST, a manual compression assistance device that enhances coagulation for patients requiring temporary hemostasis. Another key product is the VASCADE MVP, which is used for multi-site venous closure during electrophysiology procedures, such as cardiac ablation. Founded in 2002 and headquartered in Santa Clara, California, Cardiva Medical serves physicians and cardiac centers throughout the United States, focusing on transforming vascular closure practices to improve patient outcomes.

Intuity Medical, Inc. is a company focused on developing innovative blood glucose monitoring systems for diabetes management. Founded in 2002 and headquartered in Fremont, California, Intuity Medical is known for its POGO Automatic Blood Glucose Monitoring System, which is the first FDA-cleared automatic device that integrates lancing, blood collection, and analysis into a single 10-test cartridge. This system offers a convenient and discreet solution for individuals who need to regularly monitor their blood glucose levels, making it easier for millions of patients to manage their diabetes effectively. The company was previously named Rosedale Medical, Inc. before rebranding in June 2007.

Cardiva Medical, Inc. is a medical device company that specializes in vascular access management products designed to facilitate the body's healing process after catheterization procedures. The company offers several innovative products, including the VASCADE VCS, an extravascular and bioabsorbable femoral access closure system that promotes rapid hemostasis while reducing complications. Additionally, Cardiva Medical provides the Cardiva CATALYST, a manual compression assistance device that enhances coagulation for patients requiring temporary hemostasis. Another key product is the VASCADE MVP, which is used for multi-site venous closure during electrophysiology procedures, such as cardiac ablation. Founded in 2002 and headquartered in Santa Clara, California, Cardiva Medical serves physicians and cardiac centers throughout the United States, focusing on transforming vascular closure practices to improve patient outcomes.

Intuity Medical, Inc. is a company focused on developing innovative blood glucose monitoring systems for diabetes management. Founded in 2002 and headquartered in Fremont, California, Intuity Medical is known for its POGO Automatic Blood Glucose Monitoring System, which is the first FDA-cleared automatic device that integrates lancing, blood collection, and analysis into a single 10-test cartridge. This system offers a convenient and discreet solution for individuals who need to regularly monitor their blood glucose levels, making it easier for millions of patients to manage their diabetes effectively. The company was previously named Rosedale Medical, Inc. before rebranding in June 2007.

Apollo Endosurgery, Inc. is a medical technology company based in Austin, Texas, specializing in the design, development, and commercialization of innovative medical devices for gastrointestinal health. Founded in 2005, the company focuses on advancing therapeutic endoscopy as a less invasive alternative to traditional surgical procedures, thereby reducing complication rates and overall healthcare costs. Its product portfolio includes the OverStitch and OverStitch Sx Endoscopic Suturing Systems, which enable physicians to place full-thickness sutures and secure tissue approximation through flexible endoscopy. Additionally, Apollo offers the X-Tack Endoscopic HeliX Tacking System and the Orbera Intragastric Balloon, which aids in weight management by reducing stomach capacity. The company's devices cater to gastroenterologists and bariatric surgeons, addressing various gastrointestinal conditions such as acute perforations and chronic fistulas. Apollo Endosurgery's commitment to innovation is rooted in the collaborative efforts of a distinguished group of gastroenterologists and surgeons who aimed to enhance the field of therapeutic endoscopy.

Cardiva Medical, Inc. is a medical device company that specializes in vascular access management products designed to facilitate the body's healing process after catheterization procedures. The company offers several innovative products, including the VASCADE VCS, an extravascular and bioabsorbable femoral access closure system that promotes rapid hemostasis while reducing complications. Additionally, Cardiva Medical provides the Cardiva CATALYST, a manual compression assistance device that enhances coagulation for patients requiring temporary hemostasis. Another key product is the VASCADE MVP, which is used for multi-site venous closure during electrophysiology procedures, such as cardiac ablation. Founded in 2002 and headquartered in Santa Clara, California, Cardiva Medical serves physicians and cardiac centers throughout the United States, focusing on transforming vascular closure practices to improve patient outcomes.

Intersect ENT, Inc. is a medical device company focused on developing innovative therapies for patients with ear, nose, and throat conditions. Founded in 2003 and headquartered in Menlo Park, California, the company specializes in drug delivery products aimed at enhancing treatment outcomes for chronic sinusitis and other related ailments. Its key offerings include the PROPEL and PROPEL mini drug-releasing implants, designed for patients undergoing sinus surgery, as well as the PROPEL Contour implant, which targets frontal and maxillary sinus ostia. Additionally, Intersect ENT provides SINUVA, a steroid-releasing implant intended for use in a physician office setting to address refractory disease. The company was previously known as Sinexus, Inc. before rebranding in 2009.

Tryton Medical, Inc. is a medical device company based in Durham, North Carolina, specializing in the development and manufacturing of side branch stent systems designed to treat coronary bifurcation lesions in patients with cardiovascular diseases. Founded in 2003, the company provides its innovative Tryton Side Branch Stent System, which targets atherosclerotic lesions at bifurcation sites. Tryton Medical distributes its products through a global network of distributors and also addresses investigational needs within the United States. The company's offerings are available in several countries, including Austria, Belgium, Denmark, Ireland, Luxembourg, the Netherlands, Norway, Poland, Portugal, Spain, and the United Kingdom.

Mirna Therapeutics, Inc. (Mirna) is a discovery-stage biopharmaceutical research and development company focused on miRNA-directed human oncology therapies. Featuring world-class research capabilities, a strong understanding of miRNA and cancer biology, and an expansive IP portfolio, Mirna Therapeutics is well-positioned to capitalize on the emerging field of miRNA-based therapeutics.

Cardiva Medical, Inc. is a medical device company that specializes in vascular access management products designed to facilitate the body's healing process after catheterization procedures. The company offers several innovative products, including the VASCADE VCS, an extravascular and bioabsorbable femoral access closure system that promotes rapid hemostasis while reducing complications. Additionally, Cardiva Medical provides the Cardiva CATALYST, a manual compression assistance device that enhances coagulation for patients requiring temporary hemostasis. Another key product is the VASCADE MVP, which is used for multi-site venous closure during electrophysiology procedures, such as cardiac ablation. Founded in 2002 and headquartered in Santa Clara, California, Cardiva Medical serves physicians and cardiac centers throughout the United States, focusing on transforming vascular closure practices to improve patient outcomes.

Apollo Endosurgery, Inc. is a medical technology company based in Austin, Texas, specializing in the design, development, and commercialization of innovative medical devices for gastrointestinal health. Founded in 2005, the company focuses on advancing therapeutic endoscopy as a less invasive alternative to traditional surgical procedures, thereby reducing complication rates and overall healthcare costs. Its product portfolio includes the OverStitch and OverStitch Sx Endoscopic Suturing Systems, which enable physicians to place full-thickness sutures and secure tissue approximation through flexible endoscopy. Additionally, Apollo offers the X-Tack Endoscopic HeliX Tacking System and the Orbera Intragastric Balloon, which aids in weight management by reducing stomach capacity. The company's devices cater to gastroenterologists and bariatric surgeons, addressing various gastrointestinal conditions such as acute perforations and chronic fistulas. Apollo Endosurgery's commitment to innovation is rooted in the collaborative efforts of a distinguished group of gastroenterologists and surgeons who aimed to enhance the field of therapeutic endoscopy.

Cardiva Medical, Inc. is a medical device company that specializes in vascular access management products designed to facilitate the body's healing process after catheterization procedures. The company offers several innovative products, including the VASCADE VCS, an extravascular and bioabsorbable femoral access closure system that promotes rapid hemostasis while reducing complications. Additionally, Cardiva Medical provides the Cardiva CATALYST, a manual compression assistance device that enhances coagulation for patients requiring temporary hemostasis. Another key product is the VASCADE MVP, which is used for multi-site venous closure during electrophysiology procedures, such as cardiac ablation. Founded in 2002 and headquartered in Santa Clara, California, Cardiva Medical serves physicians and cardiac centers throughout the United States, focusing on transforming vascular closure practices to improve patient outcomes.

Intersect ENT, Inc. is a medical device company focused on developing innovative therapies for patients with ear, nose, and throat conditions. Founded in 2003 and headquartered in Menlo Park, California, the company specializes in drug delivery products aimed at enhancing treatment outcomes for chronic sinusitis and other related ailments. Its key offerings include the PROPEL and PROPEL mini drug-releasing implants, designed for patients undergoing sinus surgery, as well as the PROPEL Contour implant, which targets frontal and maxillary sinus ostia. Additionally, Intersect ENT provides SINUVA, a steroid-releasing implant intended for use in a physician office setting to address refractory disease. The company was previously known as Sinexus, Inc. before rebranding in 2009.

IDEV Technologies is a medical device company dedicated to developing innovative products for endovascular and interventional applications, particularly in the fields of interventional radiology, gastroenterology, vascular surgery, and cardiology. The company markets SUPERA, a unique self-expanding nitinol stent designed with a patented interwoven structure that enhances flexibility, radial strength, and resistance to kinking and crushing. SUPERA has received approval for treating biliary strictures in the United States. Additionally, IDEV is actively enrolling patients in the SUPERB IDE trial to evaluate the stent's safety and efficacy for use in the superficial femoral artery.

Tryton Medical, Inc. is a medical device company based in Durham, North Carolina, specializing in the development and manufacturing of side branch stent systems designed to treat coronary bifurcation lesions in patients with cardiovascular diseases. Founded in 2003, the company provides its innovative Tryton Side Branch Stent System, which targets atherosclerotic lesions at bifurcation sites. Tryton Medical distributes its products through a global network of distributors and also addresses investigational needs within the United States. The company's offerings are available in several countries, including Austria, Belgium, Denmark, Ireland, Luxembourg, the Netherlands, Norway, Poland, Portugal, Spain, and the United Kingdom.

Ortho Kinematics, Inc. is a healthcare diagnostics company based in Austin, Texas, specializing in spine imaging informatics. Established in 2006, it develops advanced diagnostic technology solutions for assessing spinal instability. The company offers the KineGraph Vertebral Motion Analyzer, an automated system that utilizes fluoroscopy to capture spine motion, generating patient-specific graphs that aid clinicians in diagnosing and treating back and neck pain. Additionally, Ortho Kinematics provides cloud-based analysis of instability testing results along with video X-ray imaging services through its imaging center. The company's innovations support spine clinicians by delivering critical insights into spinal health.

Ortho Kinematics, Inc. is a healthcare diagnostics company based in Austin, Texas, specializing in spine imaging informatics. Established in 2006, it develops advanced diagnostic technology solutions for assessing spinal instability. The company offers the KineGraph Vertebral Motion Analyzer, an automated system that utilizes fluoroscopy to capture spine motion, generating patient-specific graphs that aid clinicians in diagnosing and treating back and neck pain. Additionally, Ortho Kinematics provides cloud-based analysis of instability testing results along with video X-ray imaging services through its imaging center. The company's innovations support spine clinicians by delivering critical insights into spinal health.

Alereon, Inc. is a fabless semiconductor company based in Austin, Texas, specializing in the development and marketing of ultra wideband (UWB) wireless chipsets for various applications. The company offers products such as the AL5100 RF transceiver, which integrates multiple analog front-end components for seamless connectivity, and the AL5350 MAC/BBP, designed for WiMedia UWB systems. Alereon aims to simplify networking by eliminating the need for cables, allowing for easy connections between personal computers, consumer electronics, and mobile devices. Their offerings include pre-built evaluation kits for demonstration and prototyping, as well as wireless USB adapter kits and Ethernet cable replacement solutions. The company serves a diverse range of markets, including consumer electronics, medical, and military and public safety sectors. Founded in 2003, Alereon continues to innovate in wireless technology to enhance connectivity for its customers.

Cameron Health, Inc. is a development-stage medical device company focused on creating advanced implantable electronic devices aimed at improving patient care in the field of cardiac health. The company specializes in the development and manufacturing of subcutaneous implantable defibrillator (S-ICD) systems designed for patients at risk of life-threatening ventricular tachyarrhythmias. Their product line includes the SQ-RX pulse generator, which is essential for managing cardiac arrhythmias, and the Q-TRAK subcutaneous electrode, designed for optimal placement within the body. Additionally, the Q-TECH programmer enables wireless communication with the SQ-RX device, enhancing device functionality. Cameron Health's mission is to address unmet medical needs through innovative technology, leveraging the expertise of its team to tackle complex medical challenges.

Intersect ENT, Inc. is a medical device company focused on developing innovative therapies for patients with ear, nose, and throat conditions. Founded in 2003 and headquartered in Menlo Park, California, the company specializes in drug delivery products aimed at enhancing treatment outcomes for chronic sinusitis and other related ailments. Its key offerings include the PROPEL and PROPEL mini drug-releasing implants, designed for patients undergoing sinus surgery, as well as the PROPEL Contour implant, which targets frontal and maxillary sinus ostia. Additionally, Intersect ENT provides SINUVA, a steroid-releasing implant intended for use in a physician office setting to address refractory disease. The company was previously known as Sinexus, Inc. before rebranding in 2009.

Cardiva Medical, Inc. is a medical device company that specializes in vascular access management products designed to facilitate the body's healing process after catheterization procedures. The company offers several innovative products, including the VASCADE VCS, an extravascular and bioabsorbable femoral access closure system that promotes rapid hemostasis while reducing complications. Additionally, Cardiva Medical provides the Cardiva CATALYST, a manual compression assistance device that enhances coagulation for patients requiring temporary hemostasis. Another key product is the VASCADE MVP, which is used for multi-site venous closure during electrophysiology procedures, such as cardiac ablation. Founded in 2002 and headquartered in Santa Clara, California, Cardiva Medical serves physicians and cardiac centers throughout the United States, focusing on transforming vascular closure practices to improve patient outcomes.

IDEV Technologies is a medical device company dedicated to developing innovative products for endovascular and interventional applications, particularly in the fields of interventional radiology, gastroenterology, vascular surgery, and cardiology. The company markets SUPERA, a unique self-expanding nitinol stent designed with a patented interwoven structure that enhances flexibility, radial strength, and resistance to kinking and crushing. SUPERA has received approval for treating biliary strictures in the United States. Additionally, IDEV is actively enrolling patients in the SUPERB IDE trial to evaluate the stent's safety and efficacy for use in the superficial femoral artery.

Accumetrics is a privately-held company based in San Diego, California, that specializes in the development, manufacturing, and marketing of the VerifyNow System, which includes a comprehensive suite of assays for assessing platelet function. Founded in 1996, the company initially sold to Radiometer in 2000 but was repurchased by its management and investors in 2003. Accumetrics focuses on diagnostic instrumentation and test kits designed to measure individual responses to various antiplatelet agents, providing essential tools for healthcare professionals in the evaluation of platelet activity and ensuring effective patient treatment.

Asuragen, Inc. is a molecular diagnostics company based in Austin, Texas, focused on providing patient management solutions for oncology and genetic disorders. Founded in 2005, Asuragen develops and commercializes diagnostic products for clinical laboratories and biopharma partners. Its product portfolio includes the AmplideX FMR1 PCR reagents for detecting CGG repeats in the fragile X mental retardation gene, various cancer testing kits like QUANTIDEX, and the Signature technology for multiplex analysis of nucleic acid sequences, which includes assays for mutations in KRAS and BRAF genes. In addition to these diagnostic tools, Asuragen offers GLP testing services, cGMP manufacturing capabilities, and expertise in biomarker discovery and regulatory processes. This integrated approach facilitates the development, testing, and commercialization of diagnostic solutions aimed at improving treatment outcomes in oncology and genetic conditions.

Apollo Endosurgery, Inc. is a medical technology company based in Austin, Texas, specializing in the design, development, and commercialization of innovative medical devices for gastrointestinal health. Founded in 2005, the company focuses on advancing therapeutic endoscopy as a less invasive alternative to traditional surgical procedures, thereby reducing complication rates and overall healthcare costs. Its product portfolio includes the OverStitch and OverStitch Sx Endoscopic Suturing Systems, which enable physicians to place full-thickness sutures and secure tissue approximation through flexible endoscopy. Additionally, Apollo offers the X-Tack Endoscopic HeliX Tacking System and the Orbera Intragastric Balloon, which aids in weight management by reducing stomach capacity. The company's devices cater to gastroenterologists and bariatric surgeons, addressing various gastrointestinal conditions such as acute perforations and chronic fistulas. Apollo Endosurgery's commitment to innovation is rooted in the collaborative efforts of a distinguished group of gastroenterologists and surgeons who aimed to enhance the field of therapeutic endoscopy.

LDR Holding Corporation is a medical device company that specializes in developing and marketing implantable spine systems and instrumentation for both patients and surgeons. The company offers a range of spinal surgery solutions, including artificial disc systems, pedicle screw systems, cervical cages, and various implant systems designed for cervical and lumbar applications. LDR Holding also provides synthetic bone substitutes and innovative surgical technologies, such as the VerteBRIDGE product, which is tailored for specific surgical procedures. Its products are distributed in numerous countries, including Australia, Japan, and various European nations, through partnerships with surgeons and distributors. Founded in 2004 and headquartered in Austin, Texas, LDR Holding has expanded its presence internationally with additional offices in France, China, Brazil, and Germany. The company was previously known as LDR Spine USA, Inc. before rebranding following its acquisition of LDR Médical.

Alereon, Inc. is a fabless semiconductor company based in Austin, Texas, specializing in the development and marketing of ultra wideband (UWB) wireless chipsets for various applications. The company offers products such as the AL5100 RF transceiver, which integrates multiple analog front-end components for seamless connectivity, and the AL5350 MAC/BBP, designed for WiMedia UWB systems. Alereon aims to simplify networking by eliminating the need for cables, allowing for easy connections between personal computers, consumer electronics, and mobile devices. Their offerings include pre-built evaluation kits for demonstration and prototyping, as well as wireless USB adapter kits and Ethernet cable replacement solutions. The company serves a diverse range of markets, including consumer electronics, medical, and military and public safety sectors. Founded in 2003, Alereon continues to innovate in wireless technology to enhance connectivity for its customers.

On-X Life Technologies Inc. specializes in the development, manufacturing, and marketing of artificial heart valve replacement and repair products. The company's diverse product portfolio includes aortic and mitral heart valves equipped with standard, anatomic, and Conform-X sewing rings, as well as ascending aortic prostheses and chordal repair products. Additionally, On-X offers cardiovascular specialty products and provides technical services related to carbon-based technology, encompassing medical design, product development, and manufacturing. Founded in 1994 and based in Austin, Texas, the company was previously known as Medical Carbon Research Institute and rebranded in 2007. As of January 2016, On-X operates as a subsidiary of CryoLife Inc.

BioSET, Inc. specializes in the research and development of synthetic bioactive peptides aimed at enhancing bone and soft tissue repair. The company offers a range of medical devices, including AMPLEX, an implantable combination device designed for surgical bone graft applications in spine fusion and other orthopedic procedures. BioSET's product portfolio also includes innovations for sports medicine, peptide signaling molecules, and various scaffold biomaterials, all intended for use in musculoskeletal applications such as trauma, fracture repair, and soft tissue treatments. Founded in 2001 and based in Rockville, Maryland, BioSET operates as a subsidiary of Ferring Pharmaceuticals Inc.

LDR Holding Corporation is a medical device company that specializes in developing and marketing implantable spine systems and instrumentation for both patients and surgeons. The company offers a range of spinal surgery solutions, including artificial disc systems, pedicle screw systems, cervical cages, and various implant systems designed for cervical and lumbar applications. LDR Holding also provides synthetic bone substitutes and innovative surgical technologies, such as the VerteBRIDGE product, which is tailored for specific surgical procedures. Its products are distributed in numerous countries, including Australia, Japan, and various European nations, through partnerships with surgeons and distributors. Founded in 2004 and headquartered in Austin, Texas, LDR Holding has expanded its presence internationally with additional offices in France, China, Brazil, and Germany. The company was previously known as LDR Spine USA, Inc. before rebranding following its acquisition of LDR Médical.

GlycoMimetics, Inc. is a clinical-stage biotechnology company dedicated to the discovery and development of innovative glycomimetic drugs aimed at addressing significant unmet medical needs associated with diseases influenced by carbohydrate biology. The company’s lead drug candidate, rivipansel, is a pan-selectin antagonist that has completed Phase III clinical trials for treating vaso-occlusive crises in sickle cell disease. Additionally, GlycoMimetics is developing uproleselan, an E-selectin inhibitor that is being tested in combination with chemotherapy for acute myeloid leukemia (AML) and in a Phase III trial for relapsed/refractory AML. The company also offers GMI-1359, which targets E-selectin and a chemokine receptor, having completed Phase I clinical trials, and is involved in developing other candidates, including GMI-1687 and Galectin-3. GlycoMimetics has established research collaborations, including an agreement with the National Cancer Institute and a partnership with Apollomics for the commercialization of uproleselan and GMI-1687. Founded in 2003, the company is headquartered in Rockville, Maryland.

BioMimetic Therapeutics is a biotechnology company focused on developing biologically active drug-device combination products that stimulate the body's natural tissue regenerative processes. Founded in 1999 and headquartered in Franklin, Tennessee, the company offers a range of products targeting various orthopedic and sports medicine conditions. These include Augment Injectable and Augment Rotator Cuff, which are designed for applications such as foot and ankle fusions, wrist fracture healing, and rotator cuff tear surgical treatment. Additionally, the Augment Tendinopathy Injection addresses injuries related to tendon overuse. Through its innovative approaches, BioMimetic Therapeutics aims to improve healing outcomes for patients with skeletal and associated tissue injuries.

GlycoMimetics, Inc. is a clinical-stage biotechnology company dedicated to the discovery and development of innovative glycomimetic drugs aimed at addressing significant unmet medical needs associated with diseases influenced by carbohydrate biology. The company’s lead drug candidate, rivipansel, is a pan-selectin antagonist that has completed Phase III clinical trials for treating vaso-occlusive crises in sickle cell disease. Additionally, GlycoMimetics is developing uproleselan, an E-selectin inhibitor that is being tested in combination with chemotherapy for acute myeloid leukemia (AML) and in a Phase III trial for relapsed/refractory AML. The company also offers GMI-1359, which targets E-selectin and a chemokine receptor, having completed Phase I clinical trials, and is involved in developing other candidates, including GMI-1687 and Galectin-3. GlycoMimetics has established research collaborations, including an agreement with the National Cancer Institute and a partnership with Apollomics for the commercialization of uproleselan and GMI-1687. Founded in 2003, the company is headquartered in Rockville, Maryland.

Alereon, Inc. is a fabless semiconductor company based in Austin, Texas, specializing in the development and marketing of ultra wideband (UWB) wireless chipsets for various applications. The company offers products such as the AL5100 RF transceiver, which integrates multiple analog front-end components for seamless connectivity, and the AL5350 MAC/BBP, designed for WiMedia UWB systems. Alereon aims to simplify networking by eliminating the need for cables, allowing for easy connections between personal computers, consumer electronics, and mobile devices. Their offerings include pre-built evaluation kits for demonstration and prototyping, as well as wireless USB adapter kits and Ethernet cable replacement solutions. The company serves a diverse range of markets, including consumer electronics, medical, and military and public safety sectors. Founded in 2003, Alereon continues to innovate in wireless technology to enhance connectivity for its customers.