SignalFire, established in 2013 and headquartered in San Francisco, is a venture capital firm focusing on early-stage investments in technology companies. It specializes in seed, small series A, and series B rounds, typically investing up to $5 million per deal. The firm concentrates on consumer sectors like mobile, media, e-commerce, and enterprise areas such as SaaS, big data, and machine learning. SignalFire differentiates itself by providing data-driven insights and tailored advisory programs to its portfolio companies, drawing on a distributed network of industry experts.
Managing Director and Head, Competitive Intelligence
Elaine Zelby
Partner
Past deals in Predictive Analytics
Justpoint
Series A in 2025
Justpoint is an artificial intelligence-driven platform that connects individuals seeking personal injury litigation with appropriate attorneys and resources. By employing predictive analytics, Justpoint enhances transparency and efficiency in the process of identifying qualified litigators, moving away from traditional advertising methods. The platform assists law firms by managing back-office tasks and streamlining the discovery process, allowing attorneys to quickly assess the merits of claims and achieve optimal outcomes. With a network of over 1,000 law firms and access to more than 300,000 historical claims across 33 states, Justpoint aims to improve access to justice while facilitating better matches between plaintiffs and legal representation.
Qualified Health
Seed Round in 2025
Qualified Health is a technology company specializing in generative artificial intelligence (AI) for healthcare. It provides an infrastructure solution that ensures safe and effective use of AI in medicine, offering features such as continuous algorithm performance monitoring, active AI governance, and customizable AI agents tailored to healthcare needs. The company partners with leading health systems in the U.S. to revolutionize healthcare through AI.
Zeotap
Venture Round in 2024
Zeotap GmbH operates a customer intelligence platform that assists brands in understanding their customers and predicting their behavior. Founded in 2014 and headquartered in Berlin, Germany, with additional offices in New York, Bengaluru, Madrid, and Milan, Zeotap offers three main data solutions. The Zeotap Customer Data Platform (CDP) enables brands to integrate, unify, segment, and orchestrate customer data securely. Zeotap Data facilitates effective targeting through the activation of a wide range of Champion Segments across numerous programmatic and social platforms. Additionally, Zeotap ID+ serves as a universal marketing ID initiative, ensuring addressability in a cookieless future. The platform adheres to data privacy and security standards, allowing companies to manage and monetize diverse datasets while leveraging first-party data to enhance customer acquisition and loyalty.
Centaur Labs
Series B in 2024
Centaur Labs specializes in medical data annotation services, aimed at enhancing medical decision-making and diagnostics. The company utilizes a platform that connects a global network of students and professionals, who compete to provide high-quality data labeling. This collaborative model ensures exceptional accuracy and scalability in annotating medical and scientific data. By analyzing medical cases and labeling data effectively, Centaur Labs contributes to the development of advanced medical AI technologies, ultimately helping patients achieve better healthcare outcomes while potentially reducing costs.
Unify
Seed Round in 2024
Combine All Models for Faster, Cheaper, and Better Responses Than Any Single Model
Praia Health
Series A in 2024
Praia Health is a technology company that specializes in digital health solutions for hospitals. Its platform aims to enhance patient care by creating personalized health journeys, connecting patients to relevant services and resources, and providing hospitals with comprehensive patient profiles that extend beyond clinical records. This enables healthcare providers to offer more tailored and specialized care throughout the patient's health journey, fostering stronger patient relationships.
CodaMetrix
Series B in 2024
CodaMetrix is a developer of an AI-powered platform focused on automating healthcare revenue cycle management and medical coding. The platform utilizes machine learning, deep learning, and natural language processing to accurately translate clinical notes into billing and diagnostic codes. This automation not only meets coding requirements but also significantly reduces the workload for human coders. By continuously learning from clinical evidence within electronic health records and drawing from a comprehensive library of data points from national health systems, CodaMetrix enhances coding efficiency and quality, ultimately allowing healthcare providers to optimize their operations.
Nim
Pre Seed Round in 2024
Generative Video for Professionals
Kolena
Series A in 2023
Kolena is a machine learning testing platform that enables ML teams to rigorously evaluate model behavior. The platform helps identify and track failure modes, allowing engineering, sales, and customers to gain a clearer understanding of model performance and pinpoint potential gaps. By providing a robust testing infrastructure, Kolena facilitates the quality assurance of machine learning software models and their updates, thereby streamlining and enhancing machine learning and analytics projects for its clients.
Karat Financial
Series B in 2023
Karat Financial is a fintech company that specializes in providing credit card services tailored to the unique needs of creators and influencers. It offers the Karat Black Card, which uses an algorithm considering financial and social statistics to set credit limits and offer customized rewards. By understanding the often unpredictable income and diverse revenue streams of creators, Karat aims to provide them with accessible capital and financial tools that traditional banks may not offer.
CodaMetrix
Series A in 2023
CodaMetrix is a developer of an AI-powered platform focused on automating healthcare revenue cycle management and medical coding. The platform utilizes machine learning, deep learning, and natural language processing to accurately translate clinical notes into billing and diagnostic codes. This automation not only meets coding requirements but also significantly reduces the workload for human coders. By continuously learning from clinical evidence within electronic health records and drawing from a comprehensive library of data points from national health systems, CodaMetrix enhances coding efficiency and quality, ultimately allowing healthcare providers to optimize their operations.
OneSignal
Series C in 2022
OneSignal, Inc., established in 2011 and headquartered in San Mateo, California, specializes in customer engagement solutions. It offers a multi-channel platform that facilitates businesses to deliver over 8 billion messages daily, creating meaningful customer connections through personalized and timely mobile and web push notifications. The platform, which supports various major mobile application development platforms, leverages machine learning to optimize message delivery and enhance engagement.
Praisidio
Seed Round in 2021
Praisidio, Inc. is a San Francisco-based company that designs and develops augmented intelligence tools aimed at mitigating talent risk within organizations. Established in 2019, Praisidio leverages generative AI to integrate with HR and business platforms, providing rapid, ChatGPT-like responses to employee-related inquiries. The company specializes in artificial intelligence-driven software for employee retention, delivering data-driven insights that enable businesses to manage talent risks effectively. With features that include instant pre-built and customizable reports, users can quickly gather information by asking questions and selecting various chart types and report views. By focusing on employee care, Praisidio helps enterprises prevent revenue loss associated with talent turnover.
Karat Financial
Series A in 2021
Karat Financial is a fintech company that specializes in providing credit card services tailored to the unique needs of creators and influencers. It offers the Karat Black Card, which uses an algorithm considering financial and social statistics to set credit limits and offer customized rewards. By understanding the often unpredictable income and diverse revenue streams of creators, Karat aims to provide them with accessible capital and financial tools that traditional banks may not offer.
Kolena
Seed Round in 2021
Kolena is a machine learning testing platform that enables ML teams to rigorously evaluate model behavior. The platform helps identify and track failure modes, allowing engineering, sales, and customers to gain a clearer understanding of model performance and pinpoint potential gaps. By providing a robust testing infrastructure, Kolena facilitates the quality assurance of machine learning software models and their updates, thereby streamlining and enhancing machine learning and analytics projects for its clients.
January AI
Venture Round in 2021
January AI, founded in 2017 by Noosheen Hashemi, is a precision health start-up based in Menlo Park, California. The company focuses on empowering individuals to take control of their health by utilizing multi-omic science and artificial intelligence. January AI develops a platform that offers personalized biological insights, enabling users to understand their health through a suite of software and consumer products. One of its key innovations is a virtual continuous glucose monitor that provides real-time glucose insights and predictions, utilizing data from heart rate and glucose levels. This approach allows users to align their health habits with their unique biological needs, facilitating informed decisions regarding diet, exercise, and overall well-being. By prioritizing an integrated health strategy, January AI aims to transform the consumer health landscape, focusing on proactive management rather than reactive treatment.
Zeotap
Series C in 2020
Zeotap GmbH operates a customer intelligence platform that assists brands in understanding their customers and predicting their behavior. Founded in 2014 and headquartered in Berlin, Germany, with additional offices in New York, Bengaluru, Madrid, and Milan, Zeotap offers three main data solutions. The Zeotap Customer Data Platform (CDP) enables brands to integrate, unify, segment, and orchestrate customer data securely. Zeotap Data facilitates effective targeting through the activation of a wide range of Champion Segments across numerous programmatic and social platforms. Additionally, Zeotap ID+ serves as a universal marketing ID initiative, ensuring addressability in a cookieless future. The platform adheres to data privacy and security standards, allowing companies to manage and monetize diverse datasets while leveraging first-party data to enhance customer acquisition and loyalty.
PreDxion Bio
Seed Round in 2020
PreDxion Bio is an early-stage healthcare company revolutionizing testing and treatment through low-cost, user-friendly at-home diagnostics. Enabled by PreDxion’s proprietary multiplexed localized surface plasmon resonance (LSPR) technology, our first product is a rapid, saliva-based test for COVID-19, flu, pneumonia, common cold, and other respiratory diseases.
Karat Financial
Seed Round in 2020
Karat Financial is a fintech company that specializes in providing credit card services tailored to the unique needs of creators and influencers. It offers the Karat Black Card, which uses an algorithm considering financial and social statistics to set credit limits and offer customized rewards. By understanding the often unpredictable income and diverse revenue streams of creators, Karat aims to provide them with accessible capital and financial tools that traditional banks may not offer.
Zendrive
Series B in 2019
Zendrive Inc. is a San Francisco-based company that develops a mobile application designed to track various driving metrics, including speed, location, direction, and acceleration, using smartphone sensors. Founded in 2013 and initially known as Inner Circle Technologies, Zendrive focuses on enhancing road safety through data analytics. The company's platform employs artificial intelligence algorithms to analyze sensor data, delivering actionable insights related to driving behaviors such as speeding, hard braking, phone usage, and collision events. By leveraging this data, Zendrive aims to improve safety for passengers and drivers globally, offering behavioral coaching and incentives to encourage safer driving practices. As the transportation landscape shifts towards shared and on-demand services, Zendrive plays a crucial role in addressing the evolving safety needs within this context.
OneSignal
Series B in 2019
OneSignal, Inc., established in 2011 and headquartered in San Mateo, California, specializes in customer engagement solutions. It offers a multi-channel platform that facilitates businesses to deliver over 8 billion messages daily, creating meaningful customer connections through personalized and timely mobile and web push notifications. The platform, which supports various major mobile application development platforms, leverages machine learning to optimize message delivery and enhance engagement.
OneSignal
Series A in 2017
OneSignal, Inc., established in 2011 and headquartered in San Mateo, California, specializes in customer engagement solutions. It offers a multi-channel platform that facilitates businesses to deliver over 8 billion messages daily, creating meaningful customer connections through personalized and timely mobile and web push notifications. The platform, which supports various major mobile application development platforms, leverages machine learning to optimize message delivery and enhance engagement.
Juvo
Series B in 2017
Juvo Mobile Inc. is focused on creating financial identities for creditworthy individuals who are often excluded from traditional financial systems. Founded in 2014 and headquartered in San Francisco, with additional offices in São Paulo, Singapore, and Miami, Juvo collaborates with mobile network operators to leverage its proprietary Identity Scoring technology. This technology utilizes data science, machine learning, and game mechanics to develop identity-based relationships with prepaid users, thereby facilitating access to mobile financial services that were previously unattainable. By transforming subscriber consumption with real-time credit, Juvo aims to deepen connections between mobile operators and their subscribers, ultimately enhancing their ability to provide essential financial services. The company is privately held and supported by prominent figures in technology, mobile, and finance.
Nim
Generative Video for Professionals
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