Pear Bio is a biotechnology company based in Boston and London that focuses on developing precision medicine therapeutics for challenging cancer cases. By analyzing tumor biopsies and blood samples from patients, the company utilizes multi-omics approaches to identify new therapeutic targets. Their proprietary immune-microtumor system allows them to test the effectiveness of drug candidates directly on patient tumor samples. Pear Bio's innovative technology includes a specialized hydrogel that cultivates tumors outside the human body, effectively simulating drug resistance and streamlining the treatment selection process. This enables the identification of the most effective therapies for individual patients, thereby reducing the reliance on trial-and-error methods in cancer treatment.
Vitarka Therapeutics develops medical technology and solutions for various types of cancer. It is based in London, United Kingdom.
Pear Bio is a biotechnology company based in Boston and London that focuses on developing precision medicine therapeutics for challenging cancer cases. By analyzing tumor biopsies and blood samples from patients, the company utilizes multi-omics approaches to identify new therapeutic targets. Their proprietary immune-microtumor system allows them to test the effectiveness of drug candidates directly on patient tumor samples. Pear Bio's innovative technology includes a specialized hydrogel that cultivates tumors outside the human body, effectively simulating drug resistance and streamlining the treatment selection process. This enables the identification of the most effective therapies for individual patients, thereby reducing the reliance on trial-and-error methods in cancer treatment.
Multus is a London-based company established in 2019 that specializes in providing affordable and efficient growth media for the cultivated meat industry. By employing a machine learning approach, Multus develops entirely animal-free growth media tailored specifically for animal cells, helping cultivated meat companies scale their production while maintaining high performance. The company focuses on optimizing growth factor proteins produced by genetically engineered microorganisms, thereby eliminating the environmental drawbacks associated with traditional animal serum-based media. This innovative solution supports the growth of diverse animal cell types and tissues, enabling clients to produce sustainable meat products while minimizing the environmental and economic impacts of conventional meat production.
All the health information we need is within us. Just below the skin. SAVA is redefining the way people interact with their health by developing the most advanced biosensing technology science has to offer, capable of accessing bodily information in a painless, real-time and affordable way.
Samphire Neuroscience provides solutions that specialize in women's health. The company was founded in 2021 and is based in London, England.
Aksense is a biotechnology company focused on developing affordable and portable nucleic acid-based diagnostic panels for the rapid and accurate detection of pathogens. The company has created a portable rapid infection diagnostic biosensor designed to enhance healthcare by providing high-quality and safe care. Aksense's technology aims to improve antibiotic prescribing practices and public health outcomes by enabling early detection and treatment of infections. This approach reduces the spread of infections and improves patient outcomes, allowing users to achieve faster recovery through cost-effective molecular testing solutions.
Carv is a pioneering company that has developed the first wearable device specifically for skiers, functioning as a digital ski coach. Designed in collaboration with Olympians, the device features a thin smart insert that fits into any ski boot and provides real-time analytics on balance, edging, rotation, and pressure. It connects wirelessly to a smartphone, delivering immediate audio feedback through earphones, which is beneficial for both casual and advanced skiers. By offering detailed metrics and technique analysis, Carv enables users to enhance their skiing skills, analyze their performance after each run, and receive live coaching while on the slopes. This innovative approach allows skiers to train, compete, and challenge themselves in a way that was previously accessible only to elite athletes.
AromatEco assists household brands in becoming more environmentally friendly by delivering renewable flavors and perfumes. Headquartered in London, UK.
Samphire Neuroscience provides solutions that specialize in women's health. The company was founded in 2021 and is based in London, England.
Asset Direct is focused on addressing the financial needs of the underbanked population by creating a global network of financial sales agents. This innovative approach involves thousands of agents, ranging from large businesses to small local shop owners, who direct clients to financial institutions that cater to underbanked individuals. The company has developed an online platform that facilitates personal loan searches, connecting consumers with poor credit to loan providers. This platform enables instant approval for credit and offers on-the-spot financing, making it easier for consumers to access necessary financial products. Additionally, Asset Direct empowers its agent network, allowing them to effectively build businesses centered around selling financial products and services. Through these initiatives, Asset Direct aims to enhance financial inclusion and provide essential support to those who traditionally face barriers in accessing credit.
Synthace Limited is a company focused on transforming the way biological experimentation is conducted across various sectors, including health, pharmaceuticals, food, energy, agri-science, and industrial biotechnology. Established in 2011 and headquartered in London, with an additional office in Cambridge, Massachusetts, Synthace offers a cloud-based platform called Antha. This platform enables life science research and development teams to streamline their experimental processes by allowing scientists to design, plan, and execute reproducible experiments without requiring coding skills. Antha facilitates the automation of laboratory experiments and the organization of experimental data, making it easier for researchers to run complex experiments that might have been previously deemed impractical. The company has also formed a strategic partnership with Microsoft to enhance its offerings.
Kyomei is a company based in Oxford, England, founded in 2021, that focuses on developing a plant-based production system aimed at creating animal proteins for the alternative meat industry. Utilizing innovative plant cell biology, Kyomei employs a unique method to scale the production of myoglobin in plants, which enhances the umami flavor of meat alternatives. This approach not only improves the taste of plant-based products but also supports efforts to reduce carbon emissions associated with traditional animal farming. Through its sustainable practices, Kyomei aims to provide consumers with flavorful plant-based meat options while contributing to a more environmentally friendly food system.
Sequential Skin is a diagnostic platform focused on skin longevity and aging, leveraging expertise in genetics, epigenetics, and the skin microbiome. The company specializes in clinical microbiome testing for skin, scalp, and female health. Its primary offering is a skin health test that employs quantitative real-time PCR (qPCR) technology to analyze specific markers within the skin microbiome. This analysis provides individuals with a detailed understanding of their skin profile, helping them identify their unique skincare needs. By delivering personalized insights, Sequential Skin empowers individuals to make informed decisions about their skincare routines.
Sequential Skin is a diagnostic platform focused on skin longevity and aging, leveraging expertise in genetics, epigenetics, and the skin microbiome. The company specializes in clinical microbiome testing for skin, scalp, and female health. Its primary offering is a skin health test that employs quantitative real-time PCR (qPCR) technology to analyze specific markers within the skin microbiome. This analysis provides individuals with a detailed understanding of their skin profile, helping them identify their unique skincare needs. By delivering personalized insights, Sequential Skin empowers individuals to make informed decisions about their skincare routines.
Pear Bio is a biotechnology company based in Boston and London that focuses on developing precision medicine therapeutics for challenging cancer cases. By analyzing tumor biopsies and blood samples from patients, the company utilizes multi-omics approaches to identify new therapeutic targets. Their proprietary immune-microtumor system allows them to test the effectiveness of drug candidates directly on patient tumor samples. Pear Bio's innovative technology includes a specialized hydrogel that cultivates tumors outside the human body, effectively simulating drug resistance and streamlining the treatment selection process. This enables the identification of the most effective therapies for individual patients, thereby reducing the reliance on trial-and-error methods in cancer treatment.
Circadia Health specializes in developing AI-powered, FDA-approved contactless patient monitoring systems aimed at enhancing clinical outcomes. The technology enables the detection of respiratory complications from up to eight feet away, eliminating the need for physical devices on the patient or bed. By continuously monitoring respiratory rates, Circadia's system allows clinicians to predict medical events such as congestive heart failure, pneumonia, and sepsis, often hours or days in advance. A team of virtual nurses analyzes device data in conjunction with patients' electronic health records to provide personalized, predictive risk alerts around the clock. This innovative approach not only facilitates remote assessments but also aims to reduce healthcare costs while improving patient care across various settings, from hospitals to home environments.
Asset Direct is focused on addressing the financial needs of the underbanked population by creating a global network of financial sales agents. This innovative approach involves thousands of agents, ranging from large businesses to small local shop owners, who direct clients to financial institutions that cater to underbanked individuals. The company has developed an online platform that facilitates personal loan searches, connecting consumers with poor credit to loan providers. This platform enables instant approval for credit and offers on-the-spot financing, making it easier for consumers to access necessary financial products. Additionally, Asset Direct empowers its agent network, allowing them to effectively build businesses centered around selling financial products and services. Through these initiatives, Asset Direct aims to enhance financial inclusion and provide essential support to those who traditionally face barriers in accessing credit.
Kutanios is a biotechnology company based in London that specializes in the development of innovative compounds for various skincare applications, including anti-aging, sun protection, and anti-acne treatments. The firm focuses on creating biodegradable molecules that utilize a novel mechanism of action, which targets lipid peroxides generated by environmental factors such as sunlight, pollution, and tobacco smoke. By employing green technology in the manufacturing process, Kutanios aims to provide effective solutions that help prevent skin aging, sunburn, and skin cancers, catering to the needs of consumers seeking safer and more effective skincare options.
Kutanios is a biotechnology company based in London that specializes in the development of innovative compounds for various skincare applications, including anti-aging, sun protection, and anti-acne treatments. The firm focuses on creating biodegradable molecules that utilize a novel mechanism of action, which targets lipid peroxides generated by environmental factors such as sunlight, pollution, and tobacco smoke. By employing green technology in the manufacturing process, Kutanios aims to provide effective solutions that help prevent skin aging, sunburn, and skin cancers, catering to the needs of consumers seeking safer and more effective skincare options.
Untap Health has developed a pathogen monitoring platform focused on enhancing community health by detecting infections before they escalate into outbreaks. The platform analyzes wastewater samples from various sources, including commercial sites, schools, and wastewater treatment facilities, to identify viruses present in sewage. By leveraging high-frequency data, Untap provides early warnings of potential health incidents, facilitating timely interventions. This non-invasive and anonymized approach enables communities to maintain cleanliness and safety, effectively contributing to public health monitoring and management.
Multus is a London-based company established in 2019 that specializes in providing affordable and efficient growth media for the cultivated meat industry. By employing a machine learning approach, Multus develops entirely animal-free growth media tailored specifically for animal cells, helping cultivated meat companies scale their production while maintaining high performance. The company focuses on optimizing growth factor proteins produced by genetically engineered microorganisms, thereby eliminating the environmental drawbacks associated with traditional animal serum-based media. This innovative solution supports the growth of diverse animal cell types and tissues, enabling clients to produce sustainable meat products while minimizing the environmental and economic impacts of conventional meat production.
Sequential Skin is a diagnostic platform focused on skin longevity and aging, leveraging expertise in genetics, epigenetics, and the skin microbiome. The company specializes in clinical microbiome testing for skin, scalp, and female health. Its primary offering is a skin health test that employs quantitative real-time PCR (qPCR) technology to analyze specific markers within the skin microbiome. This analysis provides individuals with a detailed understanding of their skin profile, helping them identify their unique skincare needs. By delivering personalized insights, Sequential Skin empowers individuals to make informed decisions about their skincare routines.
Caura Ltd. is a London-based company established in 2018 that specializes in vehicle management solutions. The company offers a platform that enables drivers to efficiently handle various aspects of car ownership, including payments for parking, tolls, congestion charges, MOTs, vehicle tax, and insurance. Additionally, Caura provides a product called Caura Protect, which allows users to purchase and manage motor insurance through a network of insurers. The company also focuses on developing microelectronic devices that monitor health metrics such as lactate and glucose levels, along with heart-rate and accelerometry data. Furthermore, Caura creates application software that connects to these devices to generate reports and analyze the collected data.
Verifoxx provides a next-generation trust framework that facilitates secure and verifiable data collaboration while ensuring the raw source data remains confidential. The company specializes in developing blockchain software that simplifies the identity verification process for consumers, emphasizing privacy and security. Its innovative solution allows for privacy-first identity verification and efficient management of sensitive data, enabling businesses to authenticate identities without requiring customers to disclose personal information or payment details. Verifoxx aims to serve as a universal layer that connects companies, individuals, and devices, ensuring secure interactions whenever data proof is necessary.
Multus is a London-based company established in 2019 that specializes in providing affordable and efficient growth media for the cultivated meat industry. By employing a machine learning approach, Multus develops entirely animal-free growth media tailored specifically for animal cells, helping cultivated meat companies scale their production while maintaining high performance. The company focuses on optimizing growth factor proteins produced by genetically engineered microorganisms, thereby eliminating the environmental drawbacks associated with traditional animal serum-based media. This innovative solution supports the growth of diverse animal cell types and tissues, enabling clients to produce sustainable meat products while minimizing the environmental and economic impacts of conventional meat production.
Neurocess offers services as a wearable technology product that increases the training performance and reduces the risk of injury by analyzing the muscle of professional athletes.
Synthace Limited is a company focused on transforming the way biological experimentation is conducted across various sectors, including health, pharmaceuticals, food, energy, agri-science, and industrial biotechnology. Established in 2011 and headquartered in London, with an additional office in Cambridge, Massachusetts, Synthace offers a cloud-based platform called Antha. This platform enables life science research and development teams to streamline their experimental processes by allowing scientists to design, plan, and execute reproducible experiments without requiring coding skills. Antha facilitates the automation of laboratory experiments and the organization of experimental data, making it easier for researchers to run complex experiments that might have been previously deemed impractical. The company has also formed a strategic partnership with Microsoft to enhance its offerings.
Sequential Skin is a diagnostic platform focused on skin longevity and aging, leveraging expertise in genetics, epigenetics, and the skin microbiome. The company specializes in clinical microbiome testing for skin, scalp, and female health. Its primary offering is a skin health test that employs quantitative real-time PCR (qPCR) technology to analyze specific markers within the skin microbiome. This analysis provides individuals with a detailed understanding of their skin profile, helping them identify their unique skincare needs. By delivering personalized insights, Sequential Skin empowers individuals to make informed decisions about their skincare routines.
Flowbio is a wellness and fitness services company that specializes in hydration monitoring for athletes, including triathletes, cyclists, and runners. The firm has developed a real-time hydration biosensor platform that utilizes a wearable, non-invasive patch to analyze sweat and assess key biomarkers, focusing initially on electrolytes and total body fluid loss. This technology enables users to receive personalized recommendations to enhance their athletic performance by better managing their hydration levels.
Magellan Life Sciences Ltd. is a synthetic biology company based in London, United Kingdom, specializing in the development of plant-based proteins for the food and beverage industries. Established in 2018, the company focuses on creating innovative protein sweeteners, including brazzein, utilizing its proprietary protein engineering and expression platforms. These novel protein-based molecules are designed to offer non-calorific alternatives that address sugar content and associated health concerns. By providing advanced solutions for the food, health, and nutrition sectors, Magellan Life Sciences aims to meet the growing demand for healthier ingredients in consumer products.
Carv is a pioneering company that has developed the first wearable device specifically for skiers, functioning as a digital ski coach. Designed in collaboration with Olympians, the device features a thin smart insert that fits into any ski boot and provides real-time analytics on balance, edging, rotation, and pressure. It connects wirelessly to a smartphone, delivering immediate audio feedback through earphones, which is beneficial for both casual and advanced skiers. By offering detailed metrics and technique analysis, Carv enables users to enhance their skiing skills, analyze their performance after each run, and receive live coaching while on the slopes. This innovative approach allows skiers to train, compete, and challenge themselves in a way that was previously accessible only to elite athletes.
Aō Air specializes in the manufacture and retail of advanced face masks aimed at providing clean air for individuals in polluted megacities such as Beijing and London. The company utilizes patented air purifying technology, which has been independently validated to be significantly more effective than traditional masks, filtering out dust and smoke particles through an active nanofiltration system. This innovative approach allows users to commute and exercise without the risks associated with pollution, promoting respiratory health while ensuring comfort and style. Aō Air's mission focuses on empowering urban residents to reclaim their environment and breathe clean air amidst increasing urban pollution challenges.
Arthronica Ltd is a London-based company that specializes in developing an artificial intelligence platform for patient monitoring and rehabilitation, particularly focused on chronic rheumatic conditions such as arthritis. Established in 2018, the company utilizes advanced technologies, including skeletal tracking, visual strength assessments, image analysis, and video analysis, to create solutions that assist medical practitioners in monitoring and predicting disease activities. Arthronica's innovative system incorporates force-sensing vision and 3D CAD modeling to measure swelling, thereby providing critical insights into disease progression. The company is actively engaged in clinical trials in both the United Kingdom and the United States to further validate its technology and enhance patient care. Additionally, Arthronica has participated in the Entrepreneur First program, which supports individuals in building technology companies.
Flowbio is a wellness and fitness services company that specializes in hydration monitoring for athletes, including triathletes, cyclists, and runners. The firm has developed a real-time hydration biosensor platform that utilizes a wearable, non-invasive patch to analyze sweat and assess key biomarkers, focusing initially on electrolytes and total body fluid loss. This technology enables users to receive personalized recommendations to enhance their athletic performance by better managing their hydration levels.
Moona is a company focused on enhancing sleep quality through innovative technology. It offers a smart sleep device that regulates head temperature, adapting to the user’s needs throughout the night. The system, developed in 2016 and headquartered in Paris, France, utilizes a water-based cooling and heating mechanism within a thin membrane combined with memory foam. This design allows for a natural adjustment of body temperature, aiding users in falling asleep more comfortably. Additionally, Moona provides an online payment solution that offers customers a £5 discount on their purchases when using its service. For an annual subscription fee, users can enjoy unlimited discounts when shopping with Moona's retail partners, making it a cost-effective option for frequent shoppers.
Non Equity Assistance in 2020
Brightcure is solving the lack of treatment options available for patients suffering from recurrent urinary tract infections (UTIs). UTIs are one of world’s most common infections, affecting 50% of women and 12% of men worldwide. Current UTI treatments are not effective, can cause serious side effects, and often accelerate antibiotic-resistant infections. Total UTI costs currently amount over $ 8.6B per year. With UTI bacteria becoming increasingly difficult to treat, the size of the UTI market is expected to reach $ 12.41B by 2025. Brightcure utilizes the natural microbiome to reduce harmful bacteria and replenish the good bacteria in the vaginal flora. Brightcure’s bioactive intimate cream boosts the natural immune system to promote a healthy urinary tract. BrightCure was founded in 2019 and is headquartered in London, England. In 2020, BrightCure got a seed investment from SOSV and was selected as 1 out of 9 companies to be part of the world's largest biotech accelerator, Indiebio, to develop its first product. BrightCure has been selected as one of the Top 7 companies of the McKinsey Venture Challenge, Top 5 of the Mayor of London Competition, has won Imperial College's White City Innovation Program, and has taken part in the finals of ‘The Pitch’ London Competition being selected among 850 other applications.
Brightcure is solving the lack of treatment options available for patients suffering from recurrent urinary tract infections (UTIs). UTIs are one of world’s most common infections, affecting 50% of women and 12% of men worldwide. Current UTI treatments are not effective, can cause serious side effects, and often accelerate antibiotic-resistant infections. Total UTI costs currently amount over $ 8.6B per year. With UTI bacteria becoming increasingly difficult to treat, the size of the UTI market is expected to reach $ 12.41B by 2025. Brightcure utilizes the natural microbiome to reduce harmful bacteria and replenish the good bacteria in the vaginal flora. Brightcure’s bioactive intimate cream boosts the natural immune system to promote a healthy urinary tract. BrightCure was founded in 2019 and is headquartered in London, England. In 2020, BrightCure got a seed investment from SOSV and was selected as 1 out of 9 companies to be part of the world's largest biotech accelerator, Indiebio, to develop its first product. BrightCure has been selected as one of the Top 7 companies of the McKinsey Venture Challenge, Top 5 of the Mayor of London Competition, has won Imperial College's White City Innovation Program, and has taken part in the finals of ‘The Pitch’ London Competition being selected among 850 other applications.
Machine Medicine Technologies Ltd is a healthcare company that develops an artificial intelligence platform designed to assess motor characteristics in Parkinson's disease patients using video clips. Its flagship product, KELVIN-PD, employs computer vision and pose estimation techniques to objectively track patient movements, capturing key metrics related to symptoms such as tremors and bradykinesia. This platform facilitates the secure storage and management of patient data and is accessible from any device, making it both affordable and user-friendly. Established in 2017 and headquartered in London, the company aims to enhance the understanding of the brain and advance neuro-therapeutics by providing interpretable tools for behavioral measurement.
Liberum was started in September 2007 to provide a different style of broking in an industry where clients and staff were treated poorly by other institutions. Clients wanted to work with those they could trust, who knew their needs and who worked through thick and thin. They didn’t want fair-weather friends. Staff wanted a place that keenly sought their ideas, trusted their convictions and encouraged their development. Since then they have navigated a steady course and grown alongside their clients. Now they are adding new analysts and sales staff to meet client needs, expanding their coverage and innovating in the creation and delivery of unique insight for investors.
Liberum was started in September 2007 to provide a different style of broking in an industry where clients and staff were treated poorly by other institutions. Clients wanted to work with those they could trust, who knew their needs and who worked through thick and thin. They didn’t want fair-weather friends. Staff wanted a place that keenly sought their ideas, trusted their convictions and encouraged their development. Since then they have navigated a steady course and grown alongside their clients. Now they are adding new analysts and sales staff to meet client needs, expanding their coverage and innovating in the creation and delivery of unique insight for investors.
Our mission is to use technology to protect and maintain the built environment. Our first product, a patent pending unique wall climbing robot can be used for exterior painting, warehouse painting and building and infrastructure inspection and surveying.
Multus is a London-based company established in 2019 that specializes in providing affordable and efficient growth media for the cultivated meat industry. By employing a machine learning approach, Multus develops entirely animal-free growth media tailored specifically for animal cells, helping cultivated meat companies scale their production while maintaining high performance. The company focuses on optimizing growth factor proteins produced by genetically engineered microorganisms, thereby eliminating the environmental drawbacks associated with traditional animal serum-based media. This innovative solution supports the growth of diverse animal cell types and tissues, enabling clients to produce sustainable meat products while minimizing the environmental and economic impacts of conventional meat production.
Scindo is a cleantech start-up focused on developing innovative enzyme systems aimed at creating sustainable alternatives to petrochemical ingredients across various industries. The company specializes in upcycling plastic waste into valuable molecules and converting agricultural feedstocks into natural ingredients. By utilizing a novel biological platform, Scindo enables low-energy and economically viable recycling solutions, transforming low-value waste products into high-value compounds. This approach offers clients and stakeholders a practical alternative to landfill disposal and incineration, contributing to more sustainable waste management practices.
Pear Bio is a biotechnology company based in Boston and London that focuses on developing precision medicine therapeutics for challenging cancer cases. By analyzing tumor biopsies and blood samples from patients, the company utilizes multi-omics approaches to identify new therapeutic targets. Their proprietary immune-microtumor system allows them to test the effectiveness of drug candidates directly on patient tumor samples. Pear Bio's innovative technology includes a specialized hydrogel that cultivates tumors outside the human body, effectively simulating drug resistance and streamlining the treatment selection process. This enables the identification of the most effective therapies for individual patients, thereby reducing the reliance on trial-and-error methods in cancer treatment.
Aō Air specializes in the manufacture and retail of advanced face masks aimed at providing clean air for individuals in polluted megacities such as Beijing and London. The company utilizes patented air purifying technology, which has been independently validated to be significantly more effective than traditional masks, filtering out dust and smoke particles through an active nanofiltration system. This innovative approach allows users to commute and exercise without the risks associated with pollution, promoting respiratory health while ensuring comfort and style. Aō Air's mission focuses on empowering urban residents to reclaim their environment and breathe clean air amidst increasing urban pollution challenges.
Synthace Limited is a company focused on transforming the way biological experimentation is conducted across various sectors, including health, pharmaceuticals, food, energy, agri-science, and industrial biotechnology. Established in 2011 and headquartered in London, with an additional office in Cambridge, Massachusetts, Synthace offers a cloud-based platform called Antha. This platform enables life science research and development teams to streamline their experimental processes by allowing scientists to design, plan, and execute reproducible experiments without requiring coding skills. Antha facilitates the automation of laboratory experiments and the organization of experimental data, making it easier for researchers to run complex experiments that might have been previously deemed impractical. The company has also formed a strategic partnership with Microsoft to enhance its offerings.
Aksense is a biotechnology company focused on developing affordable and portable nucleic acid-based diagnostic panels for the rapid and accurate detection of pathogens. The company has created a portable rapid infection diagnostic biosensor designed to enhance healthcare by providing high-quality and safe care. Aksense's technology aims to improve antibiotic prescribing practices and public health outcomes by enabling early detection and treatment of infections. This approach reduces the spread of infections and improves patient outcomes, allowing users to achieve faster recovery through cost-effective molecular testing solutions.
Breather is an app and a provider of space-as-a-service, with a growing network of private workspaces built for productivity. It enables businesses to access flexible workspace by the hour, day, or month. Every space is designed to be comfortable, private, and productive, with plug-and-play technology that ensures that can get to work as soon as the arrival. Founded by CEO Julien Smith in 2012, the company has grown to include hundreds of locations in 10 major across the globe including New York, San Francisco, Los Angeles, and London.
eFanswer is the living community that gives you a chance to interact with your idols, discover all the curiosity and create a unique ebook with your FASK (questions).
Aksense is a biotechnology company focused on developing affordable and portable nucleic acid-based diagnostic panels for the rapid and accurate detection of pathogens. The company has created a portable rapid infection diagnostic biosensor designed to enhance healthcare by providing high-quality and safe care. Aksense's technology aims to improve antibiotic prescribing practices and public health outcomes by enabling early detection and treatment of infections. This approach reduces the spread of infections and improves patient outcomes, allowing users to achieve faster recovery through cost-effective molecular testing solutions.
Chemicle is developing a cost effective and clean chemical process to convert dairy waste into bio-plastic precursors. These are the building blocks of high-performance and totally recyclable plastics, whose production could decrease emissions during the manufacturing phase up to 70%.
AI Nutrition develops an AI that automates online grocery shopping and precision nutrition for better health outcomes.
Arthronica Ltd is a London-based company that specializes in developing an artificial intelligence platform for patient monitoring and rehabilitation, particularly focused on chronic rheumatic conditions such as arthritis. Established in 2018, the company utilizes advanced technologies, including skeletal tracking, visual strength assessments, image analysis, and video analysis, to create solutions that assist medical practitioners in monitoring and predicting disease activities. Arthronica's innovative system incorporates force-sensing vision and 3D CAD modeling to measure swelling, thereby providing critical insights into disease progression. The company is actively engaged in clinical trials in both the United Kingdom and the United States to further validate its technology and enhance patient care. Additionally, Arthronica has participated in the Entrepreneur First program, which supports individuals in building technology companies.
Volatile AI works with all of the major existing chemical sensing technologies aimed at gas detection and screening. By combining these existing sensors with AI algorithms, company's solution can speed up the detection and profiling of ingredients and substances in manufacturing processes by up to 20x.
CorNatural specializes in the development of bio-based sustainable products, focusing on transforming waste streams from industrial processes into value-added items. The company employs innovative synthetic biology and genetic engineering techniques to create a diverse range of natural products. By prioritizing sustainability, CorNatural aims to provide solutions that not only enhance product quality but also help mitigate pollution, benefiting governments, businesses, and individuals alike.
Rize is a virtual marketplace for clinical trials. It is a patient management platform used to reinvent how patients and researchers interact. The company's patient-centric platform matches people with the appropriate clinical trial and offers the ability to participate digitally. Rize Health was founded in 2019 and is headquartered in London, Ontario.
The way we move around cities is changing rapidly. More and more people are using small, shareable electric vehicles to commute - yet, the way we charge these electric vehicles is cumbersome, expensive and hinders global adoption. We’ve made it our mission to empower anyone with access to electricity to distribute energy for transport, accelerating our transition to sustainable urban mobility. Our network of battery swap stations enable local merchants to sell energy from within their store, providing instant recharge in multiple locations across the city. Founded in 2016, we’re a passionate team of engineers, designers and operations experts working on some of the most exciting hardware in the city. We’re backed by SOS Ventures and have graduated HAX, the #1 hardware accelerator in the world.
ZiO Health is a biotechnology company that focuses on transforming laboratory testing through its proprietary pocket-sized technology, which allows for point-of-care diagnostics. By combining advanced biosensor technology with machine learning algorithms, ZiO Health provides real-time testing results tailored to each patient's unique profile. This innovative approach enables users to measure, test, and detect the molecular composition of various substances, facilitating personalized health insights. The company's devices aim to optimize health management and enhance patient outcomes, allowing individuals to conduct quality home diagnostics and take proactive steps in preventing illness.
All the health information we need is within us. Just below the skin. SAVA is redefining the way people interact with their health by developing the most advanced biosensing technology science has to offer, capable of accessing bodily information in a painless, real-time and affordable way.
Machine Medicine Technologies Ltd is a healthcare company that develops an artificial intelligence platform designed to assess motor characteristics in Parkinson's disease patients using video clips. Its flagship product, KELVIN-PD, employs computer vision and pose estimation techniques to objectively track patient movements, capturing key metrics related to symptoms such as tremors and bradykinesia. This platform facilitates the secure storage and management of patient data and is accessible from any device, making it both affordable and user-friendly. Established in 2017 and headquartered in London, the company aims to enhance the understanding of the brain and advance neuro-therapeutics by providing interpretable tools for behavioral measurement.
The way we move around cities is changing rapidly. More and more people are using small, shareable electric vehicles to commute - yet, the way we charge these electric vehicles is cumbersome, expensive and hinders global adoption. We’ve made it our mission to empower anyone with access to electricity to distribute energy for transport, accelerating our transition to sustainable urban mobility. Our network of battery swap stations enable local merchants to sell energy from within their store, providing instant recharge in multiple locations across the city. Founded in 2016, we’re a passionate team of engineers, designers and operations experts working on some of the most exciting hardware in the city. We’re backed by SOS Ventures and have graduated HAX, the #1 hardware accelerator in the world.
Machine Medicine Technologies Ltd is a healthcare company that develops an artificial intelligence platform designed to assess motor characteristics in Parkinson's disease patients using video clips. Its flagship product, KELVIN-PD, employs computer vision and pose estimation techniques to objectively track patient movements, capturing key metrics related to symptoms such as tremors and bradykinesia. This platform facilitates the secure storage and management of patient data and is accessible from any device, making it both affordable and user-friendly. Established in 2017 and headquartered in London, the company aims to enhance the understanding of the brain and advance neuro-therapeutics by providing interpretable tools for behavioral measurement.
Chronomics Ltd is a tech-bio company based in Norwich, United Kingdom, founded in 2017. It specializes in manufacturing testing kits and developing an artificial intelligence platform for DNA methylation analysis. The company provides insights into biological age, smoke exposure, metabolic state, health risks, eye color, and hereditary intolerance. Chronomics aims to make biological information more accessible and actionable, addressing the complexities and costs associated with obtaining such data. By creating bio-infrastructure across various sectors, the company enhances the use of biomarkers to inform everyday decisions in areas such as telehealth, travel, and wellness. Through partnerships with major organizations, Chronomics seeks to transform the way biological information is utilized for diagnosis, personalization, and evaluation of health-related offerings.
Synthace Limited is a company focused on transforming the way biological experimentation is conducted across various sectors, including health, pharmaceuticals, food, energy, agri-science, and industrial biotechnology. Established in 2011 and headquartered in London, with an additional office in Cambridge, Massachusetts, Synthace offers a cloud-based platform called Antha. This platform enables life science research and development teams to streamline their experimental processes by allowing scientists to design, plan, and execute reproducible experiments without requiring coding skills. Antha facilitates the automation of laboratory experiments and the organization of experimental data, making it easier for researchers to run complex experiments that might have been previously deemed impractical. The company has also formed a strategic partnership with Microsoft to enhance its offerings.
Circadia Health specializes in developing AI-powered, FDA-approved contactless patient monitoring systems aimed at enhancing clinical outcomes. The technology enables the detection of respiratory complications from up to eight feet away, eliminating the need for physical devices on the patient or bed. By continuously monitoring respiratory rates, Circadia's system allows clinicians to predict medical events such as congestive heart failure, pneumonia, and sepsis, often hours or days in advance. A team of virtual nurses analyzes device data in conjunction with patients' electronic health records to provide personalized, predictive risk alerts around the clock. This innovative approach not only facilitates remote assessments but also aims to reduce healthcare costs while improving patient care across various settings, from hospitals to home environments.
Machine Medicine Technologies Ltd is a healthcare company that develops an artificial intelligence platform designed to assess motor characteristics in Parkinson's disease patients using video clips. Its flagship product, KELVIN-PD, employs computer vision and pose estimation techniques to objectively track patient movements, capturing key metrics related to symptoms such as tremors and bradykinesia. This platform facilitates the secure storage and management of patient data and is accessible from any device, making it both affordable and user-friendly. Established in 2017 and headquartered in London, the company aims to enhance the understanding of the brain and advance neuro-therapeutics by providing interpretable tools for behavioral measurement.
The way we move around cities is changing rapidly. More and more people are using small, shareable electric vehicles to commute - yet, the way we charge these electric vehicles is cumbersome, expensive and hinders global adoption. We’ve made it our mission to empower anyone with access to electricity to distribute energy for transport, accelerating our transition to sustainable urban mobility. Our network of battery swap stations enable local merchants to sell energy from within their store, providing instant recharge in multiple locations across the city. Founded in 2016, we’re a passionate team of engineers, designers and operations experts working on some of the most exciting hardware in the city. We’re backed by SOS Ventures and have graduated HAX, the #1 hardware accelerator in the world.
The way we move around cities is changing rapidly. More and more people are using small, shareable electric vehicles to commute - yet, the way we charge these electric vehicles is cumbersome, expensive and hinders global adoption. We’ve made it our mission to empower anyone with access to electricity to distribute energy for transport, accelerating our transition to sustainable urban mobility. Our network of battery swap stations enable local merchants to sell energy from within their store, providing instant recharge in multiple locations across the city. Founded in 2016, we’re a passionate team of engineers, designers and operations experts working on some of the most exciting hardware in the city. We’re backed by SOS Ventures and have graduated HAX, the #1 hardware accelerator in the world.
LOTaDATA curates geospatial ground truth data sets on a global scale. We combine public and private data for discerning customers to help them make smarter decisions.
ZiO Health is a biotechnology company that focuses on transforming laboratory testing through its proprietary pocket-sized technology, which allows for point-of-care diagnostics. By combining advanced biosensor technology with machine learning algorithms, ZiO Health provides real-time testing results tailored to each patient's unique profile. This innovative approach enables users to measure, test, and detect the molecular composition of various substances, facilitating personalized health insights. The company's devices aim to optimize health management and enhance patient outcomes, allowing individuals to conduct quality home diagnostics and take proactive steps in preventing illness.
Synthace Limited is a company focused on transforming the way biological experimentation is conducted across various sectors, including health, pharmaceuticals, food, energy, agri-science, and industrial biotechnology. Established in 2011 and headquartered in London, with an additional office in Cambridge, Massachusetts, Synthace offers a cloud-based platform called Antha. This platform enables life science research and development teams to streamline their experimental processes by allowing scientists to design, plan, and execute reproducible experiments without requiring coding skills. Antha facilitates the automation of laboratory experiments and the organization of experimental data, making it easier for researchers to run complex experiments that might have been previously deemed impractical. The company has also formed a strategic partnership with Microsoft to enhance its offerings.
Moona is a company focused on enhancing sleep quality through innovative technology. It offers a smart sleep device that regulates head temperature, adapting to the user’s needs throughout the night. The system, developed in 2016 and headquartered in Paris, France, utilizes a water-based cooling and heating mechanism within a thin membrane combined with memory foam. This design allows for a natural adjustment of body temperature, aiding users in falling asleep more comfortably. Additionally, Moona provides an online payment solution that offers customers a £5 discount on their purchases when using its service. For an annual subscription fee, users can enjoy unlimited discounts when shopping with Moona's retail partners, making it a cost-effective option for frequent shoppers.
The way we move around cities is changing rapidly. More and more people are using small, shareable electric vehicles to commute - yet, the way we charge these electric vehicles is cumbersome, expensive and hinders global adoption. We’ve made it our mission to empower anyone with access to electricity to distribute energy for transport, accelerating our transition to sustainable urban mobility. Our network of battery swap stations enable local merchants to sell energy from within their store, providing instant recharge in multiple locations across the city. Founded in 2016, we’re a passionate team of engineers, designers and operations experts working on some of the most exciting hardware in the city. We’re backed by SOS Ventures and have graduated HAX, the #1 hardware accelerator in the world.
Chronomics Ltd is a tech-bio company based in Norwich, United Kingdom, founded in 2017. It specializes in manufacturing testing kits and developing an artificial intelligence platform for DNA methylation analysis. The company provides insights into biological age, smoke exposure, metabolic state, health risks, eye color, and hereditary intolerance. Chronomics aims to make biological information more accessible and actionable, addressing the complexities and costs associated with obtaining such data. By creating bio-infrastructure across various sectors, the company enhances the use of biomarkers to inform everyday decisions in areas such as telehealth, travel, and wellness. Through partnerships with major organizations, Chronomics seeks to transform the way biological information is utilized for diagnosis, personalization, and evaluation of health-related offerings.
NeuroCreate Ltd. operates FlowCreate Innovator, an artificial intelligence platform that enhances productivity and efficiency in strategizing, problem-solving, and idea generation. Founded in 2017 and based in London, the company leverages neuroscience to optimize human cognition and work processes. By fostering a mental state known as "Flow," NeuroCreate's tools enable users to overcome challenges with ease, improving their overall well-being and creative output. The platform emphasizes a human-centered approach, aiming to integrate AI as a collaborator that enhances both work efficiency and mental health. Additionally, NeuroCreate employs a unique method known as 'NeuroDesign,' which applies neuroscience principles to create ethical digital products that support cognitive and emotional well-being at work.
Encelo Laboratories Limited, founded in 2017 and based in London, develops innovative cell isolation tools that provide researchers with non-invasive, on-demand, and remote access to individual cells. Its flagship product, the Cell Isolation Cup, enables the selective isolation of live cells from urine, preserving them for shipment. The company's technology aims to enhance personalized medicine by facilitating universal access to stem cells and making stem cell treatments more cost-effective. Encelo's solutions serve a diverse clientele, including pharmaceutical companies, academic researchers, biobanks, and clinicians, supporting advancements in stem cell research, cell separation, and cell sequencing. By offering unprecedented access to human cells, the company aims to empower researchers and improve outcomes in personalized medicine.
Magellan Life Sciences Ltd. is a synthetic biology company based in London, United Kingdom, specializing in the development of plant-based proteins for the food and beverage industries. Established in 2018, the company focuses on creating innovative protein sweeteners, including brazzein, utilizing its proprietary protein engineering and expression platforms. These novel protein-based molecules are designed to offer non-calorific alternatives that address sugar content and associated health concerns. By providing advanced solutions for the food, health, and nutrition sectors, Magellan Life Sciences aims to meet the growing demand for healthier ingredients in consumer products.
Caura Ltd. is a London-based company established in 2018 that specializes in vehicle management solutions. The company offers a platform that enables drivers to efficiently handle various aspects of car ownership, including payments for parking, tolls, congestion charges, MOTs, vehicle tax, and insurance. Additionally, Caura provides a product called Caura Protect, which allows users to purchase and manage motor insurance through a network of insurers. The company also focuses on developing microelectronic devices that monitor health metrics such as lactate and glucose levels, along with heart-rate and accelerometry data. Furthermore, Caura creates application software that connects to these devices to generate reports and analyze the collected data.
Equity Crowdfunding in 2017
Kokoon Technology Limited is a digital health company based in London, United Kingdom, specializing in sleep enhancement solutions. Founded in 2013, the company manufactures sleep sensing headphones that incorporate EEG brainwave sensing technology to monitor sleep patterns. These headphones feature active noise cancellation, noise isolation, and white noise capabilities for improved sleep quality. Additionally, Kokoon offers a mobile application that includes an audio relaxation library and sleep analysis tools, utilizing movement and EEG sensors to gain insights into individual sleep behaviors. By combining advances in sensor technology and data science, Kokoon aims to personalize and enhance the sleep experience for users.
Moona is a company focused on enhancing sleep quality through innovative technology. It offers a smart sleep device that regulates head temperature, adapting to the user’s needs throughout the night. The system, developed in 2016 and headquartered in Paris, France, utilizes a water-based cooling and heating mechanism within a thin membrane combined with memory foam. This design allows for a natural adjustment of body temperature, aiding users in falling asleep more comfortably. Additionally, Moona provides an online payment solution that offers customers a £5 discount on their purchases when using its service. For an annual subscription fee, users can enjoy unlimited discounts when shopping with Moona's retail partners, making it a cost-effective option for frequent shoppers.
Synthace Limited is a company focused on transforming the way biological experimentation is conducted across various sectors, including health, pharmaceuticals, food, energy, agri-science, and industrial biotechnology. Established in 2011 and headquartered in London, with an additional office in Cambridge, Massachusetts, Synthace offers a cloud-based platform called Antha. This platform enables life science research and development teams to streamline their experimental processes by allowing scientists to design, plan, and execute reproducible experiments without requiring coding skills. Antha facilitates the automation of laboratory experiments and the organization of experimental data, making it easier for researchers to run complex experiments that might have been previously deemed impractical. The company has also formed a strategic partnership with Microsoft to enhance its offerings.
The way we move around cities is changing rapidly. More and more people are using small, shareable electric vehicles to commute - yet, the way we charge these electric vehicles is cumbersome, expensive and hinders global adoption. We’ve made it our mission to empower anyone with access to electricity to distribute energy for transport, accelerating our transition to sustainable urban mobility. Our network of battery swap stations enable local merchants to sell energy from within their store, providing instant recharge in multiple locations across the city. Founded in 2016, we’re a passionate team of engineers, designers and operations experts working on some of the most exciting hardware in the city. We’re backed by SOS Ventures and have graduated HAX, the #1 hardware accelerator in the world.
Carv is a pioneering company that has developed the first wearable device specifically for skiers, functioning as a digital ski coach. Designed in collaboration with Olympians, the device features a thin smart insert that fits into any ski boot and provides real-time analytics on balance, edging, rotation, and pressure. It connects wirelessly to a smartphone, delivering immediate audio feedback through earphones, which is beneficial for both casual and advanced skiers. By offering detailed metrics and technique analysis, Carv enables users to enhance their skiing skills, analyze their performance after each run, and receive live coaching while on the slopes. This innovative approach allows skiers to train, compete, and challenge themselves in a way that was previously accessible only to elite athletes.
ZiO Health is a biotechnology company that focuses on transforming laboratory testing through its proprietary pocket-sized technology, which allows for point-of-care diagnostics. By combining advanced biosensor technology with machine learning algorithms, ZiO Health provides real-time testing results tailored to each patient's unique profile. This innovative approach enables users to measure, test, and detect the molecular composition of various substances, facilitating personalized health insights. The company's devices aim to optimize health management and enhance patient outcomes, allowing individuals to conduct quality home diagnostics and take proactive steps in preventing illness.
eFanswer is the living community that gives you a chance to interact with your idols, discover all the curiosity and create a unique ebook with your FASK (questions).
Aō Air specializes in the manufacture and retail of advanced face masks aimed at providing clean air for individuals in polluted megacities such as Beijing and London. The company utilizes patented air purifying technology, which has been independently validated to be significantly more effective than traditional masks, filtering out dust and smoke particles through an active nanofiltration system. This innovative approach allows users to commute and exercise without the risks associated with pollution, promoting respiratory health while ensuring comfort and style. Aō Air's mission focuses on empowering urban residents to reclaim their environment and breathe clean air amidst increasing urban pollution challenges.
ZiO Health is a biotechnology company that focuses on transforming laboratory testing through its proprietary pocket-sized technology, which allows for point-of-care diagnostics. By combining advanced biosensor technology with machine learning algorithms, ZiO Health provides real-time testing results tailored to each patient's unique profile. This innovative approach enables users to measure, test, and detect the molecular composition of various substances, facilitating personalized health insights. The company's devices aim to optimize health management and enhance patient outcomes, allowing individuals to conduct quality home diagnostics and take proactive steps in preventing illness.
LOTaDATA curates geospatial ground truth data sets on a global scale. We combine public and private data for discerning customers to help them make smarter decisions.
Circadia Health specializes in developing AI-powered, FDA-approved contactless patient monitoring systems aimed at enhancing clinical outcomes. The technology enables the detection of respiratory complications from up to eight feet away, eliminating the need for physical devices on the patient or bed. By continuously monitoring respiratory rates, Circadia's system allows clinicians to predict medical events such as congestive heart failure, pneumonia, and sepsis, often hours or days in advance. A team of virtual nurses analyzes device data in conjunction with patients' electronic health records to provide personalized, predictive risk alerts around the clock. This innovative approach not only facilitates remote assessments but also aims to reduce healthcare costs while improving patient care across various settings, from hospitals to home environments.
Néit Luggage, the world’s first Smart, Collapsible, Hard Case Luggage. Without compromising durability nor protection of your personal belongings, Néit Luggage is able to go from about 35CM to less than 8CM and simply slide under your bed or get hung next to your suits or dresses thanks to their carabiner-style handle. Not only smart in the respect that it reduces in size in a cramped space, but it also has GPS incorporated with their Travel Lifestyle app, making sure you’re never hung out to dry.
Kokoon Technology Limited is a digital health company based in London, United Kingdom, specializing in sleep enhancement solutions. Founded in 2013, the company manufactures sleep sensing headphones that incorporate EEG brainwave sensing technology to monitor sleep patterns. These headphones feature active noise cancellation, noise isolation, and white noise capabilities for improved sleep quality. Additionally, Kokoon offers a mobile application that includes an audio relaxation library and sleep analysis tools, utilizing movement and EEG sensors to gain insights into individual sleep behaviors. By combining advances in sensor technology and data science, Kokoon aims to personalize and enhance the sleep experience for users.
Breather is an app and a provider of space-as-a-service, with a growing network of private workspaces built for productivity. It enables businesses to access flexible workspace by the hour, day, or month. Every space is designed to be comfortable, private, and productive, with plug-and-play technology that ensures that can get to work as soon as the arrival. Founded by CEO Julien Smith in 2012, the company has grown to include hundreds of locations in 10 major across the globe including New York, San Francisco, Los Angeles, and London.
Kokoon Technology Limited is a digital health company based in London, United Kingdom, specializing in sleep enhancement solutions. Founded in 2013, the company manufactures sleep sensing headphones that incorporate EEG brainwave sensing technology to monitor sleep patterns. These headphones feature active noise cancellation, noise isolation, and white noise capabilities for improved sleep quality. Additionally, Kokoon offers a mobile application that includes an audio relaxation library and sleep analysis tools, utilizing movement and EEG sensors to gain insights into individual sleep behaviors. By combining advances in sensor technology and data science, Kokoon aims to personalize and enhance the sleep experience for users.
Carv is a pioneering company that has developed the first wearable device specifically for skiers, functioning as a digital ski coach. Designed in collaboration with Olympians, the device features a thin smart insert that fits into any ski boot and provides real-time analytics on balance, edging, rotation, and pressure. It connects wirelessly to a smartphone, delivering immediate audio feedback through earphones, which is beneficial for both casual and advanced skiers. By offering detailed metrics and technique analysis, Carv enables users to enhance their skiing skills, analyze their performance after each run, and receive live coaching while on the slopes. This innovative approach allows skiers to train, compete, and challenge themselves in a way that was previously accessible only to elite athletes.
Synthace Limited is a company focused on transforming the way biological experimentation is conducted across various sectors, including health, pharmaceuticals, food, energy, agri-science, and industrial biotechnology. Established in 2011 and headquartered in London, with an additional office in Cambridge, Massachusetts, Synthace offers a cloud-based platform called Antha. This platform enables life science research and development teams to streamline their experimental processes by allowing scientists to design, plan, and execute reproducible experiments without requiring coding skills. Antha facilitates the automation of laboratory experiments and the organization of experimental data, making it easier for researchers to run complex experiments that might have been previously deemed impractical. The company has also formed a strategic partnership with Microsoft to enhance its offerings.
FlickTek specializes in innovative human-machine interface (HMI) solutions that enhance user interaction through advanced sensor technology. The company focuses on developing systems that accurately read and interpret finger movements and gestures, utilizing biometric signals generated by the dynamics of tendons and body tissues. This technology enables users to control electronic devices, such as smartwatches, through simple gestures, thereby improving accessibility and user experience. With a strong foundation in biomedicine and engineering, FlickTek is committed to advancing biotechnology and foreseeing future trends, ultimately aiming to improve quality of life through seamless technological integration.
Gamer Guides is a publisher based in Manchester, UK, specializing in interactive digital strategy guides for video games. The company offers a platform that provides comprehensive game information, walkthroughs, and strategies, catering to both gaming professionals and enthusiasts. Its guides are accessible through an iOS app and the website www.gamerguides.com, allowing users to find reliable and engaging resources for navigating various video games. By centralizing game-related information, Gamer Guides aims to enhance the gaming experience for its users.
Yoyo Wallet Limited is a mobile wallet company based in London, United Kingdom, that facilitates customer transactions for retailers, universities, and corporate locations. Founded in 2013 and originally known as JustYoyo Limited, the company rebranded in April 2015. Yoyo Wallet enables users to make payments using their smartphones, processing over 150,000 monthly in-store transactions by integrating payment and loyalty features through a simple scanning process. Additionally, it offers a marketing platform that enhances digital customer engagement for retailers, allowing them to deliver loyalty programs and rewards tailored to individual buying patterns.
Breather is an app and a provider of space-as-a-service, with a growing network of private workspaces built for productivity. It enables businesses to access flexible workspace by the hour, day, or month. Every space is designed to be comfortable, private, and productive, with plug-and-play technology that ensures that can get to work as soon as the arrival. Founded by CEO Julien Smith in 2012, the company has grown to include hundreds of locations in 10 major across the globe including New York, San Francisco, Los Angeles, and London.