Targeted Technology

Cardiovate, Inc. is a medical technology company based in San Antonio, Texas, founded in 2012. The company focuses on developing innovative products for tissue regeneration and repair, specifically targeting vascular health. Its flagship product, NeoVessel, is a vascular graft designed to enhance the regeneration and repair of vascular tissues. By utilizing proprietary materials and processes, Cardiovate aims to address clinical needs in the healthcare sector, ultimately reducing failure rates and lowering the overall cost of care through advancements in vascular regeneration technology.

neoSurgical Limited is a medical device company based in Campus, Ireland, specializing in innovative solutions for laparoscopic abdominal surgery. Founded in 2007, the company has developed neoClose, a device designed to facilitate the closure of laparoscopic wounds and reduce the risk of complications such as herniation. By enhancing the safety and efficiency of laparoscopic port site closure, neoSurgical aims to improve surgical outcomes for both patients and surgeons in the field of minimally invasive surgery.

Aerin Medical Inc. is a health technology company based in Sunnyvale, California, specializing in non-invasive treatment solutions for nasal breathing disorders. Established in 2011, the company has developed therapeutic devices that utilize low-power radiofrequency energy to remodel nasal soft tissues, effectively addressing the underlying causes of nasal congestion. Its primary products include the VivAer procedure for nasal airway obstruction and the RhinAer procedure for chronic rhinitis, both of which employ proprietary temperature-controlled technology. These solutions offer ENT physicians appealing alternatives to invasive surgery, allowing them to treat patients under local anesthesia with minimal to no downtime. Aerin Medical aims to meet the unmet needs of individuals suffering from chronic nasal airway conditions through its innovative and office-friendly product offerings.

Roxy’s Remedies provides natural grooming products for dogs with canine atopic dermatitis. Roxy’s Remedies' product line is formulated with sustainably cultivated, pharmaceutical-grade East Indian Sandalwood Oil (EISO) produced by TFS Corporation Ltd. EISO is a natural, calming ingredient that has been used as a traditional skin healing agent and is being developed by Santalis as a prescription drug for human skin conditions.

StemBioSys, Inc. is a biomedical company based in San Antonio, Texas, established in 2010. The company specializes in the isolation, expansion, and delivery of adult stem cells for various applications, including research, diagnostics, and clinical use. StemBioSys develops proprietary technologies, such as its advanced BM-HPME stem cell culture system, which mimics the natural environment of stem cells, promoting their growth and viability. The company's innovations aim to support regenerative medicine and address a range of human diseases, including diabetes, Alzheimer’s, Parkinson’s, inflammatory disorders, and osteoarthritis. By identifying clinical applications and collaborating with other organizations, StemBioSys seeks to advance stem cell technologies for broader use in healthcare.

Xenex is a company focused on reducing healthcare-associated infections (HAIs) through its advanced ultraviolet disinfection technology. Founded in 2009 and based in San Antonio, Texas, Xenex has developed a portable device that utilizes pulsed xenon UV light to eliminate harmful microorganisms in hospital environments. Since launching its disinfection system in June 2010, the company’s devices have been integrated into infection control protocols in nearly three hundred hospitals across the United States. By effectively reducing the bacterial load that contributes to HAIs, Xenex aims to enhance patient safety and safeguard healthcare staff, ultimately striving to save lives and alleviate suffering in healthcare settings.

DNAtrix, Inc. is a clinical-stage biotechnology company based in Texas that specializes in developing virus-driven immunotherapies for cancer treatment. The company’s leading product, DNX-2401, is an oncolytic immunotherapy designed to target and kill glioblastoma cells, a particularly aggressive form of brain cancer. This therapy has shown promising early results, with over 35 patients treated. DNAtrix is also developing additional armed DNX viruses, specifically DNX-2440 and DNX-2450, aimed at treating various solid tumors, as well as MYX-135, which targets hematological malignancies. With a focus on harnessing modified viruses to selectively destroy cancer cells while stimulating the immune system, DNAtrix seeks to expand its platform to address other cancers, including brain metastases, ovarian, and pancreatic cancers. The company was incorporated in 2005 and maintains its headquarters in Houston, Texas, with an additional office in San Diego, California.

Bluegrass Vascular Technologies, Inc. is a medical technology company focused on developing and commercializing innovative devices to improve vascular access procedures for patients with obstructed central venous systems. The company's flagship product, the Surfacer Inside-Out Access Catheter System, allows physicians to achieve central venous access by inserting a guide wire through the femoral vein and guiding it to exit at either the jugular or subclavian vein. This system is designed to enhance patient safety and reduce complications during vascular access procedures. Founded in 2010 and headquartered in San Antonio, Texas, Bluegrass Vascular Technologies serves patients both in the United States and internationally.

Xenex is a company focused on reducing healthcare-associated infections (HAIs) through its advanced ultraviolet disinfection technology. Founded in 2009 and based in San Antonio, Texas, Xenex has developed a portable device that utilizes pulsed xenon UV light to eliminate harmful microorganisms in hospital environments. Since launching its disinfection system in June 2010, the company’s devices have been integrated into infection control protocols in nearly three hundred hospitals across the United States. By effectively reducing the bacterial load that contributes to HAIs, Xenex aims to enhance patient safety and safeguard healthcare staff, ultimately striving to save lives and alleviate suffering in healthcare settings.

ViroXis Corporation is a bio-pharmaceutical company based in San Antonio, Texas, specializing in the development and commercialization of botanical pharmaceuticals derived from East Indian sandalwood oil. The company has developed a proprietary botanical ointment that utilizes a defined mixture from Santalum album, aimed at treating human papillomavirus (HPV) infections of the skin in both children and adults. Additionally, ViroXis is working on an EISO cream to address other HPV-related conditions. The company has established strategic partnerships with TFS Corporation Ltd. and DPT Laboratories, Inc. Founded in 2006, ViroXis operates as a subsidiary of TFS Corporation Ltd. as of 2015.

Bi02 Medical, Inc. specializes in the design, development, manufacture, and commercialization of medical devices aimed at addressing clinical needs. The company's flagship product, the Angel Catheter, is an inferior vena cava (IVC) filter designed to protect against prophylactic pulmonary embolism and facilitate access to the central venous system in critically ill patients. This device allows for the administration of medications, fluids, and blood products, as well as blood sampling and monitoring of central venous pressure. Bi02 Medical's products are distributed globally through various partners. Founded in 2006, the company is headquartered in San Antonio, Texas, and operates a research and development and manufacturing facility in Golden, Colorado.

Bi02 Medical, Inc. specializes in the design, development, manufacture, and commercialization of medical devices aimed at addressing clinical needs. The company's flagship product, the Angel Catheter, is an inferior vena cava (IVC) filter designed to protect against prophylactic pulmonary embolism and facilitate access to the central venous system in critically ill patients. This device allows for the administration of medications, fluids, and blood products, as well as blood sampling and monitoring of central venous pressure. Bi02 Medical's products are distributed globally through various partners. Founded in 2006, the company is headquartered in San Antonio, Texas, and operates a research and development and manufacturing facility in Golden, Colorado.

Vidacare Corporation is a medical device company based in San Antonio, Texas, specializing in intraosseous access devices designed for use in diagnostic, monitoring, and therapeutic applications. The company’s flagship product, the EZ-IO Product System, enables controlled vascular access through the intraosseous route, particularly beneficial in emergency situations where traditional vascular access methods are ineffective. The EZ-IO power driver is engineered to penetrate the intraosseous space using a hollow needle and integrated stylet, ensuring accurate placement. Additionally, the EZ-IO Vascular Access Pack equips emergency medical personnel with the necessary tools to establish vascular access quickly. Vidacare also offers a range of hematology and oncology products, including systems for bone marrow aspiration and biopsy. Its innovations are utilized in various settings, including pre-hospital care, emergency response, and military operations, catering to the needs of healthcare providers in critical situations. Founded in 2001, Vidacare continues to advance intraosseous access technology for the medical community.