Rege Nephro
Series B in 2024
Rege Nephro Co., Ltd. is a biotechnology company based in Kyoto, Japan, founded in 2019. It specializes in the research and development, production, and marketing of therapeutics for renal diseases, utilizing nephron progenitor cells and induced pluripotent stem cell (iPSC) technology from the Center for iPS Cell Research and Application at Kyoto University. The company focuses on developing innovative treatments and cell therapies for kidney, liver, and pancreas diseases, aiming to reduce the reliance on dialysis for patients with renal failure. Additionally, Rege Nephro produces kidney organoids that facilitate nephrotoxicity screening for drug discovery, enhancing applied research in the field of nephrology.
Hakko Holdings
Seed Round in 2024
Hakko Holdings is a food-tech company focused on producing and manufacturing fermented plant-based foods using innovative fermentation technology. The company specializes in enhancing nutrition and flavor through its unique processes, offering a diverse range of soy and legume-based products. Its portfolio includes high-protein, low-water-use options made from specially cultivated lupin beans and soybeans. By providing delicious and wholesome alternatives, Hakko Holdings aims to promote healthy and sustainable lifestyles for consumers.
Luxna Biotech
Series C in 2024
Luxna Biotech Co., Ltd., founded in 2017 and headquartered in Suita, Japan, specializes in the development of nucleic acid drugs. The company employs innovative technologies to expedite the practical application of these drugs, offering drug discovery support services that leverage artificial nucleic acid technology. Its mission is to alleviate suffering by contributing to improved medical treatments.
On-Chip Biotechnologies
Venture Round in 2024
On-Chip Biotechnologies Co., Ltd., founded in 2005 and based in Tokyo, Japan, specializes in the development and manufacturing of advanced medical devices for biosafety applications. The company is known for its innovative FISHMAN-R analyzer, which utilizes flow cytometry on a microfluidics chip to detect and analyze specific bacteria and cells using the Flow-FISH method. This device is capable of detecting particles ranging from 0.5μm to 20μm and can analyze small sample quantities while measuring forward scatter and scattered light in the direction of a laser. Additionally, On-Chip Biotechnologies produces cell sorting devices that enable damage-free and contamination-free separation of cells. Their technology incorporates a liquid transfer system mounted on a disposable microchannel chip, eliminating the need for additional tanks and reducing cellular stress during the sorting process.
LIGHTz is an artificial intelligence-based company that specializes in consulting, system development, and product development services. It operates an online knowledge-sharing platform designed to streamline the process of information management. By leveraging AI technology, LIGHTz's platform helps organizations efficiently manage content, create onboarding instructions for employees, and reduce training costs and time. This innovative approach enables clients to effectively transfer their expert knowledge and skills, enhancing overall productivity and operational efficiency.
Green Chemical
Seed Round in 2024
Green Chemical is a chemical manufacturing company specializing in the production of bioplastic raw materials designed to replace petroleum-based products. The company utilizes innovative catalyst and production technology to convert inedible biomass resources into hydroxymethylfurfural, a crucial aromatic compound for bioplastics and various other chemicals. By focusing on sustainable practices, Green Chemical aims to expand the bioplastics market by offering a carbon-neutral alternative to traditional plastics, thereby promoting environmentally friendly solutions in the chemical industry.
RevolKa is a biotechnology company focused on developing bio-products and pharmaceuticals for the healthcare sector. The firm aims to enhance global health by cultivating and evolving proteins, which are essential components of bio-products, through the application of artificial intelligence. This innovative approach enables medical researchers to deliver reliable and timely medical services, thereby contributing to improved health outcomes worldwide.
AZUL Energy
Series A in 2023
AZUL Energy is a pioneering company focused on enhancing air battery performance through innovative catalyst technology. The company specializes in the development and manufacturing of metal-free catalytic electrodes and electrolysis catalysts, which are designed to optimize energy systems and promote a recycling-oriented society. AZUL Energy's research has demonstrated that its catalyst electrodes, which utilize unique pigments, outperform traditional materials such as platinum carbon. By providing cost-effective and resource-efficient solutions, AZUL Energy aims to facilitate the production of green hydrogen and support the transition to sustainable energy practices. Through its eco-friendly products, the company also advocates for new lifestyles that align with environmental sustainability.
LIGHTz
Venture Round in 2023
LIGHTz is an artificial intelligence-based company that specializes in consulting, system development, and product development services. It operates an online knowledge-sharing platform designed to streamline the process of information management. By leveraging AI technology, LIGHTz's platform helps organizations efficiently manage content, create onboarding instructions for employees, and reduce training costs and time. This innovative approach enables clients to effectively transfer their expert knowledge and skills, enhancing overall productivity and operational efficiency.
SEQSENSE develops autonomous mobile robots and related products.
ElevationSpace
Seed Round in 2022
ElevationSpace is a space startup focused on on-orbit construction and transportation. The company develops platforms for space utilization and recovery, facilitating scientific research and experimentation in microgravity environments. By manufacturing small artificial satellites designed to return deliverables to Earth, ElevationSpace provides clients with essential services for conducting space experiments and advancing research activities. Their innovative approach aims to enhance the capabilities of space operations and broaden the applications of satellite technology.
Epigeneron
Venture Round in 2021
Epigeneron, Inc. is a biotechnology company based in Chuo, Japan, founded in 2015. The company focuses on the research, development, manufacturing, and marketing of pharmaceutical drugs, particularly in the areas of cancer, dementia, metabolic disorders, and infectious diseases. Epigeneron specializes in drug discovery, offering services that include the development of epigenetic and antimicrobial drugs. The company employs advanced techniques such as chromatin immunoprecipitation to isolate specific genomic regions, thereby facilitating the identification of molecules that interact with these regions. This innovative approach enables the development of gene therapies aimed at treating severe immune diseases and other serious health conditions, including fibrosis and disorders of the central nervous system. Additionally, Epigeneron is involved in the manufacture and sale of research reagents, diagnostic agents, and research equipment, alongside supporting drug discovery efforts through information services and intellectual property transfer.
ALE is a pioneering company founded in 2011 that specializes in creating innovative space entertainment experiences, including the world's first man-made meteor showers. By utilizing microsatellites to release particles that create atmospheric phenomena, ALE aims to merge meteor science with entertainment, stimulating public curiosity about space and science. The company operates with two primary goals: to entertain and inspire people while collecting valuable data from the mesosphere to enhance understanding of atmospheric phenomena and contribute to climate change research. ALE fosters a collaborative community of scientists, decision-makers, and the general public, promoting the exploration of the universe and encouraging a sustainable future on Earth. Through its unique approach, ALE connects scientific knowledge with societal interest, making the cosmos an engaging cultural sphere.
Sound Wave Innovation
Venture Round in 2020
Sound Wave Innovation is a medical device manufacturer specializing in the development of advanced ultrasound and shockwave systems. The company focuses on creating minimally invasive treatment technologies that utilize low-power pulsed wave ultrasound and shockwave ablation catheter systems. These innovative devices are designed to assist medical professionals in treating conditions such as severe angina pectoris, mild dementia, and arrhythmia. By prioritizing technological innovation, Sound Wave Innovation aims to enhance health and welfare through its cutting-edge medical solutions. An online inquiry form is available on the company’s website for interested parties.
Epigno Inc., founded in 2016 and based in Tokyo, Japan, specializes in management solutions for medical and nursing care institutions. The company focuses on enhancing human resource management, particularly for nursing staff, by alleviating their workload and improving retention rates within healthcare organizations. Epigno’s platform aims to support the ongoing education and evaluation of nurses, thereby fostering a more effective and sustainable healthcare environment. By addressing the challenges faced by medical and nursing personnel, Epigno contributes to a more efficient operational framework that ultimately benefits patients and their families.
Kringle Pharma
Venture Round in 2020
Kringle Pharma, Inc. is a biopharmaceutical company based in Ibaraki, Japan, founded in 2001. The company specializes in the research and development of hepatocyte growth factor (HGF) protein medicines, which have regenerative healing properties for liver cells and other organs. Kringle Pharma focuses on creating HGF products aimed at treating a range of conditions, including acute spinal cord injury, amyotrophic lateral sclerosis (ALS), acute kidney injury associated with ALS, and vocal fold scars. Additionally, the company explores the therapeutic potential of NK4, a bi-functional molecule that acts as an HGF-antagonist with antiangiogenic properties, targeting cancer therapies. Kringle Pharma's innovative approach positions it at the forefront of developing treatments for intractable diseases.
Piezo Studio
Series A in 2019
Piezo Studio Inc. is a manufacturing company based in Sendai, Japan, specializing in the design, development, and pre-production of electronic devices. Founded in 2014, the company offers a range of products, including resonators, sensing devices, and material filters for low power wireless communications. In addition to its product offerings, Piezo Studio provides cut and polish services for crystals, as well as consulting and material evaluation services, enhancing its capabilities in material development. Through its comprehensive approach, the company aims to meet the diverse needs of the electronics market.
Goryo Chemical
Venture Round in 2019
Goryo Chemical, Inc. is a Japanese company specializing in the development of fluorescent probes and functional dyes for applications in chemical biology and diagnostics. Founded in 2010 and headquartered in Sapporo, with an additional office in Tokyo, the company offers a range of products including AcidiFluor, CalFluor, GlycoFluor, and MetalloFluor, among others. These fluorescent probes are designed for cellular analysis, assay, and imaging, enabling selective staining of acidic organelles such as lysosomes and late endosomes. Goryo Chemical also provides bioluminescent probes, labeling services, and custom synthesis, catering to various needs in molecularly-targeted drug and immunoassay applications. The company serves its customers through a network of distributors both domestically and internationally.
AI Silk
Venture Round in 2019
AI Silk Corporation, established in 2015 and based in Sendai, Japan, specializes in the manufacture and sale of innovative conductive fibers. The company's flagship product, AI Silk, is created using a unique dyeing technique that imbues natural silk with conductivity. This advancement allows for the production of electrodes that address common issues associated with traditional medical electrodes, such as discomfort, skin irritation, and measurement inaccuracies caused by sweat. AI Silk’s technology not only enhances the comfort of conductive clothing but also minimizes the risk of allergic reactions, making it suitable for a wide range of applications beyond the healthcare sector. The company also offers simplified manufacturing kits, further promoting the use of its advanced materials in various industries.
Future Standard
Series C in 2019
Future Standard Co., Ltd., established in Tokyo, Japan, in March 2014, specializes in video analysis software. It develops AI-driven image processing solutions, transforming camera footage into actionable data. The company's platform offers cloud-based computer vision technologies and middleware, allowing clients to tailor video analysis services to their specific requirements and budget.
TBA is a biotech firm that provides rapid genetic testing to create a safe and healthy community. They will work to strengthen the neighborhood and contribute to building a safe and healthy society. They will seek to spread awareness of the STH approach, which enables quick genetic testing and helps to build a safe and healthy society.
SpinSensingFactory
Venture Round in 2018
SpinSensingFactory Co., Ltd. is a manufacturing company based in Sendai, Japan, specializing in the development, production, and sale of magnetic sensors and biological sensing systems. Founded in 2018, the company focuses on creating ultra-sensitive, compact, and lightweight tunnel magnetoresistive effect sensors, which cater to various industrial and medical applications. These advanced sensors enable clients to utilize cutting-edge technology in their operations, enhancing the efficiency and effectiveness of their sensing needs.
PD Aerospace
Corporate Round in 2018
PD Aerospace, Ltd. is a Japanese company based in Nagoya, founded in 2007, specializing in the development and manufacture of rocket and spacecraft engines and components. The company focuses on creating a fully reusable sub-orbital spacecraft capable of reaching altitudes of 100 kilometers, facilitating space travel and experiments in the unique environment of space. PD Aerospace also provides technical support for customer product development and new business initiatives, aiming to make space more accessible. Additionally, the company is engaged in the development of a hybrid rocket-jet craft designed to transport up to eight passengers on suborbital flights, thereby enhancing commercial space travel opportunities.
Ball Wave
Series B in 2018
Ball Wave Inc. is a technology company based in Sendai, Japan, established in 2015. It specializes in the development, manufacturing, and sale of advanced sensors, including trance moisture sensors, mini sensors, and ball surface acoustic wave (SAW) gas sensors. These spherical sensors and analyzers are designed for chemical sensing, delivering high sensitivity, small size, and rapid response times. Ball Wave's innovative sensor technology enables users to detect various environmental attributes, such as moisture and hydrogen, at the nanoscale, thus positioning the company at the forefront of sensor technology.
JAMPT Corporation
Venture Round in 2018
JAMPT Corporation, founded in 2017 and based in Tagajho, Japan, specializes in the manufacturing and sale of additive manufacturing (AM) metal powder. As the first service bureau in Japan dedicated to metal AM, the company provides a wide range of services that encompass powder development, prototype modeling, and mass production. It leverages academic expertise from Tohoku University and collaborates with industry partners to enhance its technological capabilities. JAMPT Corporation is committed to optimizing the manufacturing process for its clients by offering integrated support in contract modeling, material development, and product development, thereby improving quality and efficiency in metal AM applications.
Kringle Pharma
Venture Round in 2018
Kringle Pharma, Inc. is a biopharmaceutical company based in Ibaraki, Japan, founded in 2001. The company specializes in the research and development of hepatocyte growth factor (HGF) protein medicines, which have regenerative healing properties for liver cells and other organs. Kringle Pharma focuses on creating HGF products aimed at treating a range of conditions, including acute spinal cord injury, amyotrophic lateral sclerosis (ALS), acute kidney injury associated with ALS, and vocal fold scars. Additionally, the company explores the therapeutic potential of NK4, a bi-functional molecule that acts as an HGF-antagonist with antiangiogenic properties, targeting cancer therapies. Kringle Pharma's innovative approach positions it at the forefront of developing treatments for intractable diseases.
RTi-cast
Venture Round in 2018
RTi-cast is a company focused on providing real-time data related to tsunami inundation and damage estimation systems. Its platform offers critical forecast information and calculation results that help individuals and organizations take necessary precautions against natural disasters. In addition to its data services, RTi-cast is involved in research, development, education, and consulting on disaster-related phenomena. The company's efforts aim to enhance public awareness and preparedness, enabling communities to better protect themselves from the impacts of tsunamis and other natural disasters.
AI Silk
Venture Round in 2018
AI Silk Corporation, established in 2015 and based in Sendai, Japan, specializes in the manufacture and sale of innovative conductive fibers. The company's flagship product, AI Silk, is created using a unique dyeing technique that imbues natural silk with conductivity. This advancement allows for the production of electrodes that address common issues associated with traditional medical electrodes, such as discomfort, skin irritation, and measurement inaccuracies caused by sweat. AI Silk’s technology not only enhances the comfort of conductive clothing but also minimizes the risk of allergic reactions, making it suitable for a wide range of applications beyond the healthcare sector. The company also offers simplified manufacturing kits, further promoting the use of its advanced materials in various industries.
Renascience
Venture Round in 2018
Renascience is a research and development firm focused on creating innovative medical solutions to address various health challenges. The company employs a range of modalities, including pharmaceuticals, medical devices, and artificial intelligence, to develop treatments and enhance patient care. By combining advanced research techniques with practical applications, Renascience aims to improve medical outcomes and contribute to the advancement of healthcare.
Ispace Technologies
Series A in 2018
Ispace Technologies is a Tokyo-based company specializing in space resource exploration, particularly focused on developing micro-robotic technology to facilitate the identification, extraction, and transportation of lunar resources, such as ice, essential for sustaining human life in space. Founded in 2013, Ispace is recognized for its innovative approach, utilizing 3D printing and commercially available products to create efficient and cost-effective solutions. The company is also involved in the Google Lunar XPRIZE Competition through its Team HAKUTO, which has gained recognition for its advancements in mobility and aims to land a privately funded robot on the Moon. Ispace’s micro-robots are designed to explore larger lunar areas quickly and economically, making significant strides towards establishing a sustainable presence in outer space.
Sendai Smart Machines
Venture Round in 2017
Sendai Smart Machines Co., Ltd. specializes in the development and manufacture of high-sensitivity sensors and sensor networks, focusing on the Industrial Internet of Things (IIoT). The company creates MEMS-based IoT devices, including innovative vibration energy harvesters designed to operate reliably in harsh environments, such as those found in automobiles, railways, and industrial plants. These devices facilitate continuous wireless data transmission without the need for wired power sources or battery charging, contributing to a safer and more efficient social infrastructure. By addressing the challenges of severe vibratory conditions, Sendai Smart Machines enables clients to monitor critical data effectively and sustainably.
Tohoku Magnet Institute
Venture Round in 2017
Tohoku Magnet Institute specializes in the development, manufacturing, sales, and licensing of ultra-low-loss soft magnetic materials, including ribbons and particulates. These advanced materials serve as magnetic core components for a variety of applications, including home appliances, industrial equipment, automobiles, and energy systems. By offering alternatives to traditional silicon steel sheets, Tohoku Magnet Institute's products enhance energy efficiency and improve performance in electrical devices. The company's innovative approach addresses the growing demand for energy-saving solutions in the electrical and electronics industries.
Pan Solution Technologies
Venture Round in 2017
Pan Solution Technologies specializes in the development of advanced evaluation technology for solar power generation and semiconductor manufacturing. The company produces materials for solar cells and inspection equipment designed to address challenges within the semiconductor industry. Its innovative technology measures energy conversion efficiency in silicon wafers and quantifies the number of electrons contributing to power generation through a singular parameter. This capability enables semiconductor manufacturers to enhance quality, reduce costs, and improve production efficiency. By focusing on both solar energy and semiconductor applications, Pan Solution Technologies aims to contribute to the advancement of sustainable energy solutions and optimize manufacturing processes.
HG Precision
Venture Round in 2017
HG Precision provides metal and injection molding manufactures, industrial and electronics manufactures,medical pharmaceutical and automotive and aircraft manufactures and automation equipment manufacturers.
Neu, Inc. operates a managed online cleaning platform that connects housekeepers and domestic workers with providers of vacation rental cleaning services. Founded in 2017 and based in Seattle, Washington, the company aims to streamline the cleaning industry by employing technology to bridge traditional methods with modern efficiencies. Neu focuses on enhancing the customer experience for vacation rental hosts through a user-friendly interface and a network of skilled cleaners. By positioning itself to disrupt the service industry, Neu aspires to become a leading entity in the cleaning sector.
Piezo Studio
Venture Round in 2017
Piezo Studio Inc. is a manufacturing company based in Sendai, Japan, specializing in the design, development, and pre-production of electronic devices. Founded in 2014, the company offers a range of products, including resonators, sensing devices, and material filters for low power wireless communications. In addition to its product offerings, Piezo Studio provides cut and polish services for crystals, as well as consulting and material evaluation services, enhancing its capabilities in material development. Through its comprehensive approach, the company aims to meet the diverse needs of the electronics market.
TMS Japan
Venture Round in 2017
TMS Co., Ltd. is a Tokyo-based clinical-stage biotechnology company specializing in the development of drug candidates and medical technologies derived from academic research. Founded in 2005, TMS focuses on fungus-derived small molecule compounds known as SMTPs, which exhibit dual modes of action, providing both thrombolytic and anti-inflammatory effects. The company's lead compound, TMS-007, is currently undergoing Phase IIa clinical trials for the treatment of acute ischemic stroke and is partnered with a prominent biotech firm. TMS aims to advance its innovative medical products to address significant health challenges.
TMS Co., Ltd., established in 2005 and headquartered in Tokyo, Japan, is a clinical-stage biotechnology company. It specializes in developing drug candidates and medical technologies derived from academic research. TMS focuses on a unique group of small molecule compounds, known as SMTPs, which exhibit both thrombolytic and anti-inflammatory properties. The company's lead compound, TMS-007, is currently in a Phase IIa clinical trial for the treatment of acute ischemic stroke, in partnership with Biogen.
Sendai Smart Machines
Venture Round in 2016
Sendai Smart Machines Co., Ltd. specializes in the development and manufacture of high-sensitivity sensors and sensor networks, focusing on the Industrial Internet of Things (IIoT). The company creates MEMS-based IoT devices, including innovative vibration energy harvesters designed to operate reliably in harsh environments, such as those found in automobiles, railways, and industrial plants. These devices facilitate continuous wireless data transmission without the need for wired power sources or battery charging, contributing to a safer and more efficient social infrastructure. By addressing the challenges of severe vibratory conditions, Sendai Smart Machines enables clients to monitor critical data effectively and sustainably.
HG Precision
Venture Round in 2016
HG Precision provides metal and injection molding manufactures, industrial and electronics manufactures,medical pharmaceutical and automotive and aircraft manufactures and automation equipment manufacturers.
Tohoku Magnet Institute
Venture Round in 2016
Tohoku Magnet Institute specializes in the development, manufacturing, sales, and licensing of ultra-low-loss soft magnetic materials, including ribbons and particulates. These advanced materials serve as magnetic core components for a variety of applications, including home appliances, industrial equipment, automobiles, and energy systems. By offering alternatives to traditional silicon steel sheets, Tohoku Magnet Institute's products enhance energy efficiency and improve performance in electrical devices. The company's innovative approach addresses the growing demand for energy-saving solutions in the electrical and electronics industries.
Ball Wave
Series A in 2016
Ball Wave Inc. is a technology company based in Sendai, Japan, established in 2015. It specializes in the development, manufacturing, and sale of advanced sensors, including trance moisture sensors, mini sensors, and ball surface acoustic wave (SAW) gas sensors. These spherical sensors and analyzers are designed for chemical sensing, delivering high sensitivity, small size, and rapid response times. Ball Wave's innovative sensor technology enables users to detect various environmental attributes, such as moisture and hydrogen, at the nanoscale, thus positioning the company at the forefront of sensor technology.
HG Precision
Seed Round in 2016
HG Precision provides metal and injection molding manufactures, industrial and electronics manufactures,medical pharmaceutical and automotive and aircraft manufactures and automation equipment manufacturers.
HG Precision
Seed Round in 2016
HG Precision provides metal and injection molding manufactures, industrial and electronics manufactures,medical pharmaceutical and automotive and aircraft manufactures and automation equipment manufacturers.
Tohoku Magnet Institute
Venture Round in 2015
Tohoku Magnet Institute specializes in the development, manufacturing, sales, and licensing of ultra-low-loss soft magnetic materials, including ribbons and particulates. These advanced materials serve as magnetic core components for a variety of applications, including home appliances, industrial equipment, automobiles, and energy systems. By offering alternatives to traditional silicon steel sheets, Tohoku Magnet Institute's products enhance energy efficiency and improve performance in electrical devices. The company's innovative approach addresses the growing demand for energy-saving solutions in the electrical and electronics industries.
RevolKa is a biotechnology company focused on developing bio-products and pharmaceuticals for the healthcare sector. The firm aims to enhance global health by cultivating and evolving proteins, which are essential components of bio-products, through the application of artificial intelligence. This innovative approach enables medical researchers to deliver reliable and timely medical services, thereby contributing to improved health outcomes worldwide.