Trendlines

IBI-Ag is a biotechnology company dedicated to developing innovative bioinsecticides designed to provide environmentally friendly pest management solutions for agriculture. The company focuses on creating natural single-domain antibody insecticides that enhance crop production while ensuring safety for farm workers, consumers, and the environment. IBI-Ag employs advanced technology to produce efficient and selective bio-insect control solutions, which are cost-effective due to their suitability for fermentation. This approach allows farmers to cultivate their crops at lower costs while benefiting from customized biological pest control options that are based on comprehensive testing and research. Through its commitment to sustainability and innovation, IBI-Ag aims to support farmers worldwide in achieving safe and productive agricultural practices.

Arcuro Medical Ltd. is focused on developing advanced solutions for meniscus repair in the knee. Established in 2013 and based in Misgav, Israel, the company has introduced its proprietary SuperBall repair system, which features a knotless all-suture anchor and a unique delivery mechanism designed for anatomic joint repair. This innovative system allows medical professionals to perform meniscus repairs safely and effectively within the joint space using specialized suture material, addressing the needs of patients with meniscus tears. Through its technology, Arcuro Medical aims to enhance the quality and reliability of meniscus repair procedures.

Celleste Bio is a company that focuses on innovative cell culture techniques to produce high-quality cocoa ingredients. By utilizing naturally occurring cocoa cells, the company eliminates the need for traditional cocoa tree cultivation, offering a sustainable alternative to conventional cocoa production. This approach allows businesses to access environmentally friendly food ingredients without the challenges associated with growing cocoa trees. Celleste Bio's commitment to sustainability and quality positions it as a leader in providing high-value agro products while addressing the environmental impacts of conventional cocoa farming.

AgriG8 is an agricultural fintech platform focused on closing the financing gap for smallholder farmers. By integrating real-time monitoring with proprietary behavioral analysis, the company provides measurement, reporting, and verification (MRV) capabilities. This technology enables lenders to engage in predictive modeling and active monitoring, thus making investments in climate-resilient farming more attractive. AgriG8's primary objective is to facilitate access to financing for farmers who adopt climate-resilient practices, thereby promoting sustainable agriculture while enhancing financial opportunities for both farmers and lenders.

Peptobiotics is a biotechnology startup focused on livestock disease prevention through innovative synthetic biology solutions. The company specializes in the development of recombinant custom peptides cultivated from synthetic microorganisms, which serve as antibiotic alternatives for promoting animal health and growth. By providing farmers and breeders with effective tools to protect livestock against pathogens, Peptobiotics aims to enhance agricultural productivity while ensuring humane and sustainable practices. The company’s approach addresses the critical need for disease prevention in livestock without contributing to antibiotic resistance, thereby fostering a more responsible and sustainable agricultural ecosystem.

ViAqua Therapeutics Ltd is an innovative biotechnology company based in Misgav, Israel, focused on developing therapeutics for the aquaculture industry. Founded in 2014, ViAqua is pioneering an orally administered particle-based platform that aims to prevent viral epidemics affecting aquatic species. The company utilizes a proprietary RNAi nanoparticle formulation that activates a cellular response to disable viral infections. This technology enables the delivery of coated nanoparticles through feed or immersion, significantly enhancing the resistance of shrimp and other aquaculture species to viral diseases. With a management team possessing extensive experience in business development and industrial biotechnology, ViAqua Therapeutics is positioned to make a substantial impact on the health and sustainability of aquaculture practices.

Insectta Pte. Ltd., established in 2017 and based in Singapore, specializes in the production of biomaterials derived from black soldier fly insects. Its primary products include pet feed, organic plant fertilizers, and various biomaterials such as chitosan, organic semiconductors, and protein and probiotics. Insectta's innovative approach aims to create a circular economy within the insect farming industry, converting waste into high-value products for applications across agrifood, pharmaceutical, and electronics sectors.

Celleste Bio is a company that focuses on innovative cell culture techniques to produce high-quality cocoa ingredients. By utilizing naturally occurring cocoa cells, the company eliminates the need for traditional cocoa tree cultivation, offering a sustainable alternative to conventional cocoa production. This approach allows businesses to access environmentally friendly food ingredients without the challenges associated with growing cocoa trees. Celleste Bio's commitment to sustainability and quality positions it as a leader in providing high-value agro products while addressing the environmental impacts of conventional cocoa farming.

PlanetWatchers, Inc. is a technology company based in San Francisco, California, founded in 2016. It specializes in geospatial analytics and offers a software-as-a-service (SaaS) platform that enables enterprises, governments, and non-governmental organizations to monitor their natural assets across various sectors, including forestry and oil and gas. Utilizing advanced machine learning algorithms and synthetic aperture radar (SAR) technology, the company transforms extensive manual data collection into rapid automated analysis. This capability allows for efficient monitoring and alerting systems that provide critical insights for managing large-scale assets, supporting industries such as crop insurance by ensuring accurate analysis and validation of claims on a global scale.

Phytolon Ltd is a company based in Misgav, Israel, specializing in the development of natural food colorants. Founded in 2000, Phytolon utilizes a novel fermentation technology that employs baker's yeast cells as biofactories to produce high-quality, plant-based food colors. This innovative approach offers a healthy alternative to synthetic food dyes, providing food manufacturers with safe, cost-effective, and stable all-natural color solutions. The company's mission is to leverage scientific advancements to promote human health and environmental sustainability in the food industry.

TierraSpec is a technology company focused on measuring and validating carbon sequestration in agricultural soils. It has developed a platform that utilizes remote sensing combined with advanced machine learning modeling and unique testing methods. This innovative approach enables farmers to accurately assess the carbon content in their fields, facilitating their participation in carbon credit markets. By providing precise measurements of carbon sequestration, TierraSpec aims to support sustainable agricultural practices and contribute to climate change mitigation efforts.

SetBone Medical is a healthcare company focused on developing innovative bone cement specifically for the treatment of vertebral compression fractures (VCF), primarily caused by osteoporosis. The company's technology features an advanced acrylic formulation that avoids toxic monomers, ensuring safety during medical procedures. Additionally, SetBone Medical's bone cement has a low exothermic reaction, which maintains a reduced curing temperature to prevent damage to surrounding tissues. This allows orthopedic surgeons to perform treatments for spinal fractures more effectively and with a lower risk of complications.

AgriG8 is an agricultural fintech platform focused on closing the financing gap for smallholder farmers. By integrating real-time monitoring with proprietary behavioral analysis, the company provides measurement, reporting, and verification (MRV) capabilities. This technology enables lenders to engage in predictive modeling and active monitoring, thus making investments in climate-resilient farming more attractive. AgriG8's primary objective is to facilitate access to financing for farmers who adopt climate-resilient practices, thereby promoting sustainable agriculture while enhancing financial opportunities for both farmers and lenders.

FruitSpec Ltd. is a company that specializes in designing and manufacturing hyperspectral sensor systems for fruit yield estimation. Founded in 2016 and based in Tel Aviv, Israel, FruitSpec provides innovative sensor pods that scan and analyze orchards to generate detailed reports. These reports include quantitative data on fruit counts and size distributions, as well as heat maps illustrating the distribution of fruit quantities within specific orchards. Utilizing advanced hyper-spectral imaging and deep learning algorithms, FruitSpec's technology assists farmers, distributors, and insurance companies in optimizing the demand-to-supply process. By enabling agribusinesses to capture essential farm data and predict yields early in the season, FruitSpec enhances decision-making capabilities in the fruit value chain.

Vensica is a medical technology company focused on developing an innovative ultrasound-based drug delivery system for the treatment of urinary bladder conditions, particularly overactive bladder (OAB) and bladder cancer. The company's approach seeks to overcome the limitations of traditional drug administration methods, which involve catheter insertion and are often painful and ineffective. By utilizing ultrasound technology, Vensica's system allows for a needle-free, quick, and pain-free drug instillation procedure. The application of ultrasound enhances drug uptake and penetration into the bladder wall, aiming to improve treatment efficacy and reduce the high recurrence rates commonly associated with urinary bladder cancer. This method represents a significant advancement in therapeutic approaches, enabling healthcare providers to offer safer and more effective treatment options for patients.

Fidmi Medical is an Israeli start-up established in 2014, focused on the development of innovative feeding devices aimed at improving nutrition delivery and enhancing the quality of life for patients unable to consume food orally. The company's devices address the limitations of existing feeding methods by providing a secure, reliable, and discreet solution for enteral feeding. Fidmi Medical's technology facilitates the direct delivery of food, liquids, and medications into the stomach, ensuring ease of use with straightforward insertion, replacement, and removal procedures.

CoreBone is a developer of a bioactive bone graft material intended for dental, orthopedic, and spine applications. The company specializes in a patented technology that incorporates bioactive minerals, such as silicium, into the structure of corals during their growth. This innovative approach results in a 100% mineral bone graft material that exhibits bone-like qualities, including strength, porosity, resorption, and bioactivity, while eliminating the risks associated with human or animal-derived materials. Founded by CEO Ohad Schwartz and CTO Prof. Itzhak Binederman, CoreBone has established a strong intellectual property portfolio and possesses significant expertise in cultivating coral for medical use, positioning itself as a leader in the development of natural alternatives for bone grafting.

AgroScout Ltd. is an Israeli company established in 2017 that specializes in developing an artificial intelligence-based platform aimed at enhancing sustainable farming practices. The company's technology provides precision agriculture solutions by utilizing advanced analytics and high-resolution aerial imagery to assess crop health and monitor for pests and diseases. AgroScout's platform supports farmers by offering insights on crop emergence, stand counts, canopy coverage, and biomass throughout the growing season. This continuous monitoring allows for early detection of infestations, enabling more effective curative treatments and reducing pesticide use. By delivering actionable insights into crop management and regional outbreak predictions, AgroScout aims to improve crop yields and profitability while fostering a more sustainable food production supply chain.

Equinom is an innovative food-tech company focused on developing non-GMO plant-based ingredients through a unique combination of agricultural expertise, culinary knowledge, and advanced technology. By addressing the historical emphasis on crops primarily for animal feed, Equinom aims to meet the increasing demand for plant-based foods, which is projected to only meet half of the expected market needs. The company employs proprietary Manna™ technology, utilizing artificial intelligence to accelerate the breeding of high-yield crops naturally, without genetic modification. This approach not only enhances the flavor and nutritional value of meat and dairy alternatives but also promotes biodiversity and climate resilience, essential for future food security. Collaborating with partners such as Meatless Farm and Roquette, Equinom has established itself as a trusted supplier of superior ingredients, supported by significant investments from industry leaders like BASF and Roquette. Through its commitment to sustainable development and precision breeding, Equinom is positioned to play a critical role in the evolving landscape of plant-based consumption.

IBI-Ag is a biotechnology company dedicated to developing innovative bioinsecticides designed to provide environmentally friendly pest management solutions for agriculture. The company focuses on creating natural single-domain antibody insecticides that enhance crop production while ensuring safety for farm workers, consumers, and the environment. IBI-Ag employs advanced technology to produce efficient and selective bio-insect control solutions, which are cost-effective due to their suitability for fermentation. This approach allows farmers to cultivate their crops at lower costs while benefiting from customized biological pest control options that are based on comprehensive testing and research. Through its commitment to sustainability and innovation, IBI-Ag aims to support farmers worldwide in achieving safe and productive agricultural practices.

ViAqua Therapeutics Ltd is an innovative biotechnology company based in Misgav, Israel, focused on developing therapeutics for the aquaculture industry. Founded in 2014, ViAqua is pioneering an orally administered particle-based platform that aims to prevent viral epidemics affecting aquatic species. The company utilizes a proprietary RNAi nanoparticle formulation that activates a cellular response to disable viral infections. This technology enables the delivery of coated nanoparticles through feed or immersion, significantly enhancing the resistance of shrimp and other aquaculture species to viral diseases. With a management team possessing extensive experience in business development and industrial biotechnology, ViAqua Therapeutics is positioned to make a substantial impact on the health and sustainability of aquaculture practices.

PlanetWatchers, Inc. is a technology company based in San Francisco, California, founded in 2016. It specializes in geospatial analytics and offers a software-as-a-service (SaaS) platform that enables enterprises, governments, and non-governmental organizations to monitor their natural assets across various sectors, including forestry and oil and gas. Utilizing advanced machine learning algorithms and synthetic aperture radar (SAR) technology, the company transforms extensive manual data collection into rapid automated analysis. This capability allows for efficient monitoring and alerting systems that provide critical insights for managing large-scale assets, supporting industries such as crop insurance by ensuring accurate analysis and validation of claims on a global scale.

ZygoFix is a medical device company specializing in spine technology. It has developed an innovative three-dimensional-printed implant designed to lock the facet joint of the lumbar spine. This device leverages the anatomy of the spine to provide stability, eliminating the need for traditional external screw-based bridges and reducing the reliance on pedicle screws. By doing so, ZygoFix aims to minimize the risks associated with improper screw placement, thereby enhancing safety in spinal surgeries. The company's focus on advancing spinal stability reflects its commitment to improving patient outcomes in the medical field.

Limaca Medical is focused on advancing the field of precision medicine through the development of an innovative ultrasound-guided biopsy system. This cutting-edge device enhances the diagnostic process for tumors in the gastrointestinal system by providing reliable, high-quality core tissue samples. Traditional methods often deliver subpar tissue samples, hindering accurate diagnosis and clinical outcomes. Limaca Medical's electro-mechanically driven endoscopic device addresses these shortcomings, enabling medical practitioners to obtain superior tissue specimens for histopathologic analysis, thereby improving diagnostic accuracy and patient care.

Phytolon Ltd is a company based in Misgav, Israel, specializing in the development of natural food colorants. Founded in 2000, Phytolon utilizes a novel fermentation technology that employs baker's yeast cells as biofactories to produce high-quality, plant-based food colors. This innovative approach offers a healthy alternative to synthetic food dyes, providing food manufacturers with safe, cost-effective, and stable all-natural color solutions. The company's mission is to leverage scientific advancements to promote human health and environmental sustainability in the food industry.

Vessi Medical is an Israeli medical device startup focused on innovating treatment for Non-Muscle-Invasive Bladder Cancer (NMIBC) through a novel surface cryotherapy approach. This technique employs extreme cold to freeze and eliminate abnormal tissue, providing a minimally invasive alternative to the standard TransUrethral Resection of Bladder Tumor (TURBT), which is often inadequate and requires invasive surgery under general anesthesia. Vessi's technology, comprising a standalone console and a disposable catheter, allows for targeted cell destruction while safeguarding healthy bladder tissue. This office-based procedure not only reduces the need for costly hospital stays and repeat surgeries but also addresses the high recurrence rate of NMIBC, which affects millions globally. With promising proof of concept already demonstrated in animal studies, Vessi aims to capture the $1.2 billion NMIBC market, while also exploring future applications for treating overactive bladder and urinary tract infections. The company is supported by experienced professionals in the medical device and cryotherapy sectors, ensuring a strong foundation for its innovations.

Saturas Ltd. is an Israeli company that specializes in the development and manufacture of sensor-based irrigation systems designed for precision agriculture. Founded in 2013 and based in Misgav, the company creates innovative miniature stem water potential sensors that are embedded in the trunks of trees, vines, and plants. These sensors provide accurate and continuous measurements of water status, enabling farmers to optimize irrigation practices, reduce water consumption, and enhance fruit production and quality. The Saturas system includes miniature implanted sensors, wireless transponders, and a central control unit that communicates with irrigation controllers. This setup allows for real-time monitoring and automated irrigation tailored to the specific needs of crops, which can result in increased yields and improved fruit characteristics such as size and sugar content. Overall, Saturas aims to improve water efficiency in agriculture while supporting farmers in maximizing their crop productivity.

Insectta Pte. Ltd., established in 2017 and based in Singapore, specializes in the production of biomaterials derived from black soldier fly insects. Its primary products include pet feed, organic plant fertilizers, and various biomaterials such as chitosan, organic semiconductors, and protein and probiotics. Insectta's innovative approach aims to create a circular economy within the insect farming industry, converting waste into high-value products for applications across agrifood, pharmaceutical, and electronics sectors.

AgroScout Ltd. is an Israeli company established in 2017 that specializes in developing an artificial intelligence-based platform aimed at enhancing sustainable farming practices. The company's technology provides precision agriculture solutions by utilizing advanced analytics and high-resolution aerial imagery to assess crop health and monitor for pests and diseases. AgroScout's platform supports farmers by offering insights on crop emergence, stand counts, canopy coverage, and biomass throughout the growing season. This continuous monitoring allows for early detection of infestations, enabling more effective curative treatments and reducing pesticide use. By delivering actionable insights into crop management and regional outbreak predictions, AgroScout aims to improve crop yields and profitability while fostering a more sustainable food production supply chain.

OrthoSpin Limited is a medical technology company based in Misgav, Israel, founded in 2014. It specializes in the development of innovative robotic external fixation systems designed to enhance patient treatment for bone injuries and limb deformities. The company's dynamic external fixators aim to address the challenges associated with traditional systems, which can be cumbersome and painful while requiring significant maintenance. OrthoSpin's proprietary technology incorporates a lightweight motor and a control box that facilitate automatic, continuous adjustments to the fixation frame without patient involvement. This smart system not only helps ensure that prescribed treatment protocols are followed but also allows physicians to monitor patient progress in real-time and make necessary adjustments to treatment plans. The company's focus on improving clinical outcomes and reducing complications positions it as a significant player in the orthopedic field.

AlgaHealth is focused on the development of innovative microalgal sources for the production of high-quality fucoxanthin, a compound with applications in health and cosmetics. The company has created a novel microalgae cultivation algorithm that enhances efficiency by 15% to 50%, alongside processing protocols designed to significantly reduce production costs to about 20% of current levels. In addition to fucoxanthin, AlgaHealth aims to produce polysaccharides as a by-product, thereby offering a secondary source of valuable microalgal products. The company's advanced methods for cultivating microalgae inland and its unique strains will allow for the commercial production of premium-quality fucoxanthin, catering to the growing market demand for quality additives in health supplements and skincare products. This positions AlgaHealth as a key player in sustainable biotechnology practices and the advancement of effective health solutions.

Equinom is an innovative food-tech company focused on developing non-GMO plant-based ingredients through a unique combination of agricultural expertise, culinary knowledge, and advanced technology. By addressing the historical emphasis on crops primarily for animal feed, Equinom aims to meet the increasing demand for plant-based foods, which is projected to only meet half of the expected market needs. The company employs proprietary Manna™ technology, utilizing artificial intelligence to accelerate the breeding of high-yield crops naturally, without genetic modification. This approach not only enhances the flavor and nutritional value of meat and dairy alternatives but also promotes biodiversity and climate resilience, essential for future food security. Collaborating with partners such as Meatless Farm and Roquette, Equinom has established itself as a trusted supplier of superior ingredients, supported by significant investments from industry leaders like BASF and Roquette. Through its commitment to sustainable development and precision breeding, Equinom is positioned to play a critical role in the evolving landscape of plant-based consumption.

AquiNovo is a company focused on developing innovative feed additives aimed at enhancing fish growth in the aquaculture industry. As the demand for fish protein rises and marine resources become increasingly depleted, AquiNovo addresses the need for sustainable solutions that optimize fish yields while utilizing existing resources and infrastructures. The company’s platform specializes in the creation of non-genetically modified and non-hormonal peptides that significantly improve gut performance and overall health in fish. This advancement not only boosts production yields for farmers but also offers potential treatments for gastrointestinal conditions in both production and companion animals, thereby contributing to the sustainability and efficiency of aquaculture practices.

ProJini Agchem is developing a solution focused on new type of molecular targets: protein-protein interactions. While such interactions are at the core of any organism, it is very challenging to develop inhibitors for such systems via conventional approaches due to their spatial and chemical characteristics. The platform, developed by scientists Maayan Gal, PhD and Itay Bloch at the Migal Galilee Research Institute Ltd., leverages a combination of computational-biophysical methods to tackle this significant challenge. ProJini Agchem received an exclusive license to use this platform to develop novel pesticides with new modes of action.

BioFishency Ltd. is an Israeli company founded in 2013, specializing in innovative water treatment systems for land-based aquaculture. The company has developed a cost-effective, all-in-one solution that integrates various water treatment methods to enhance the conditions for fish farming. BioFishency's system addresses two critical challenges in aquaculture: limited water availability and the buildup of toxic ammonia, which is produced by fish waste. By improving water quality, the system allows fish farms to double or triple their production while utilizing their existing infrastructure. This approach not only increases profitability for farmers but also promotes sustainability by minimizing ecological impact and resource use.

The Agency for Science, Technology and Research (A*STAR) is a Singaporean government agency established in 1991, dedicated to promoting scientific research and technological innovation. It oversees 18 research entities focused on biomedical sciences and physical sciences and engineering, primarily located in Biopolis and Fusionopolis. A*STAR plays a crucial role in advancing Singapore's economic sectors by providing essential intellectual, human, and industrial resources to industry partners. Additionally, the agency supports extramural research collaborations with universities, hospitals, and research centers, both locally and internationally, while nurturing talent and leadership within the research community.

Saturas Ltd. is an Israeli company that specializes in the development and manufacture of sensor-based irrigation systems designed for precision agriculture. Founded in 2013 and based in Misgav, the company creates innovative miniature stem water potential sensors that are embedded in the trunks of trees, vines, and plants. These sensors provide accurate and continuous measurements of water status, enabling farmers to optimize irrigation practices, reduce water consumption, and enhance fruit production and quality. The Saturas system includes miniature implanted sensors, wireless transponders, and a central control unit that communicates with irrigation controllers. This setup allows for real-time monitoring and automated irrigation tailored to the specific needs of crops, which can result in increased yields and improved fruit characteristics such as size and sugar content. Overall, Saturas aims to improve water efficiency in agriculture while supporting farmers in maximizing their crop productivity.

AlgaHealth is focused on the development of innovative microalgal sources for the production of high-quality fucoxanthin, a compound with applications in health and cosmetics. The company has created a novel microalgae cultivation algorithm that enhances efficiency by 15% to 50%, alongside processing protocols designed to significantly reduce production costs to about 20% of current levels. In addition to fucoxanthin, AlgaHealth aims to produce polysaccharides as a by-product, thereby offering a secondary source of valuable microalgal products. The company's advanced methods for cultivating microalgae inland and its unique strains will allow for the commercial production of premium-quality fucoxanthin, catering to the growing market demand for quality additives in health supplements and skincare products. This positions AlgaHealth as a key player in sustainable biotechnology practices and the advancement of effective health solutions.

ElastiMed Ltd. is a medical device company specializing in innovative compression therapy solutions. Founded in 2015 and based in M.P. Misgav, Israel, ElastiMed develops wearable devices that utilize advanced smart materials to enhance circulation in the legs. Their flagship product, a smart compression sock, employs proprietary technology to compress and massage the legs in response to electrical stimulation. This device is aimed at treating chronic venous insufficiency and preventing conditions such as deep vein thrombosis, swelling, and leg ulcers. ElastiMed's solutions offer patients a comfortable, effective, and affordable treatment option, catering particularly to the needs of elderly individuals suffering from venous and lymphatic diseases.

FruitSpec Ltd. is a company that specializes in designing and manufacturing hyperspectral sensor systems for fruit yield estimation. Founded in 2016 and based in Tel Aviv, Israel, FruitSpec provides innovative sensor pods that scan and analyze orchards to generate detailed reports. These reports include quantitative data on fruit counts and size distributions, as well as heat maps illustrating the distribution of fruit quantities within specific orchards. Utilizing advanced hyper-spectral imaging and deep learning algorithms, FruitSpec's technology assists farmers, distributors, and insurance companies in optimizing the demand-to-supply process. By enabling agribusinesses to capture essential farm data and predict yields early in the season, FruitSpec enhances decision-making capabilities in the fruit value chain.

Gordian Surgical Ltd. is a company specializing in the development of laparoscopic equipment, founded in 2012 and based in Misgav, Israel. The company has created the TroClose 1200, an integrated port closure solution that facilitates the opening and suturing of the abdominal wall during laparoscopic procedures. With three U.S. patents covering various aspects of laparoscopic technology, including trocar systems and suture anchor deployment methods, Gordian Surgical aims to provide surgeons with a simple, secure, and effective product for abdominal wall closure. The company's innovative technology enhances surgical procedures by ensuring improved closure of the internal tissue layer, thereby increasing safety and efficiency in laparoscopic surgeries. Following the development of an initial prototype, Gordian Surgical began preclinical trials in mid-2013.

EdenShield Ltd. is an Israel-based AgTech company founded in 2012, specializing in the development of nontoxic insect control products for greenhouse crops. The company offers a range of organic and chemical-free solutions, including EdenNet, EdenDirect, and EdenForte, which are formulated from botanical extracts and nutrients derived from native Israeli semi-desert plants. These products utilize proprietary aromatic ingredients that mask plant odors and reduce insect attraction, effectively preventing pest-related damage and the spread of viruses. EdenShield's innovative approach helps growers enhance the yield and health of crops, including cannabis, vegetables, and flowers, while promoting environmentally friendly agricultural practices.

MetoMotion is a company focused on creating a multipurpose robotic system, known as GRoW, aimed at addressing labor-intensive tasks in greenhouse vegetable production, particularly for greenhouse tomatoes. The company's robotic platform leverages artificial intelligence to identify and locate ripe fruit, facilitating seamless integration with existing farming systems. This innovation allows growers to enhance their greenhouse operations by providing valuable insights that can lead to increased yield and quality while minimizing waste. By reducing reliance on human labor, MetoMotion seeks to lower operational costs and improve efficiency in the agricultural sector.

Hargol™ FoodTech is the world's first commercial grasshopper farm! Grasshoppers are nature's most efficient protein source. Hargol™ FoodTech revolutionize the protein ingredient industry by providing a healthier and more sustainable and affordable alternative, becoming the leading intensive rearing company of grasshoppers in the world. The company is at the forefront of high quality nutrients and healthy grasshoppers supply to markets around the world, improving current market wild-harvested supply by providing year-round availability, nutrients content & quality and costs reduction. For its first line of products, Hargol FoodTech relies on methods and technologies of intensive breeding and growing of three grasshopper species that are processed into protein powders. The company is offering grasshopper based protein ingredient in North America markets to food/ingredient manufacturers and whole grasshoppers. Hargol™ FoodTech have thus far been attracting the interest of food producers, distributors and retailers in the North America, Europe and other regions of the world with whole grasshoppers, grasshopper’s nutrient-rich powder and innovative food products. With the expected 70% rise in demand for animal source protein over the next decades and with existing animal source protein taking a big toll on the environment there is a need for an alternative – Both sustainable and affordable for populations around the globe. Enhanced by their vegetarian diet grasshoppers’ nutrient content is superior compare to other insects or animal source protein: Over 70% whole protein, Omega-3 & Omega-6, Zinc, Iron, & Folic acid. Grasshoppers are also the only Kosher and Halal insect in the world!

Saturas Ltd. is an Israeli company that specializes in the development and manufacture of sensor-based irrigation systems designed for precision agriculture. Founded in 2013 and based in Misgav, the company creates innovative miniature stem water potential sensors that are embedded in the trunks of trees, vines, and plants. These sensors provide accurate and continuous measurements of water status, enabling farmers to optimize irrigation practices, reduce water consumption, and enhance fruit production and quality. The Saturas system includes miniature implanted sensors, wireless transponders, and a central control unit that communicates with irrigation controllers. This setup allows for real-time monitoring and automated irrigation tailored to the specific needs of crops, which can result in increased yields and improved fruit characteristics such as size and sugar content. Overall, Saturas aims to improve water efficiency in agriculture while supporting farmers in maximizing their crop productivity.

EdenShield Ltd. is an Israel-based AgTech company founded in 2012, specializing in the development of nontoxic insect control products for greenhouse crops. The company offers a range of organic and chemical-free solutions, including EdenNet, EdenDirect, and EdenForte, which are formulated from botanical extracts and nutrients derived from native Israeli semi-desert plants. These products utilize proprietary aromatic ingredients that mask plant odors and reduce insect attraction, effectively preventing pest-related damage and the spread of viruses. EdenShield's innovative approach helps growers enhance the yield and health of crops, including cannabis, vegetables, and flowers, while promoting environmentally friendly agricultural practices.

Catalyst AgTech Ltd. is an Israeli company focused on developing innovative technology for the agriculture sector, specifically aimed at minimizing the environmental impact of agrochemical products. The company has created a customizable technology with a self-destruction mechanism designed for use in persistent pesticides, herbicides, and fungicides. This patented catalyst technology effectively breaks down specific chemicals in fertilizers, significantly reducing their harmful effects after application and preventing groundwater contamination. By addressing the growing demand for essential pesticides while mitigating adverse environmental consequences, Catalyst AgTech offers a solution that promotes sustainable agricultural practices. The company is supported by an experienced management team and benefits from scientific collaboration with the Weizmann Institute of Science.

Valentis Nanotech, established in 2013, specializes in the production of innovative polymeric films, coatings, and compounds utilizing cellulose nanocrystals (CNC) combined with nanoparticles. The company's patented technology enables the creation of biodegradable and transparent materials derived from plant pulp waste, resulting in films that are thin, strong, and environmentally friendly. These films offer enhanced properties, such as improved strength, better spectral control, and effective barriers against UV rays, oxygen, and moisture. Valentis has engaged in collaborations with a prominent agricultural thermoplastics company in Israel since July 2014, focusing on new product development to meet specific industry needs.

LapSpace Medical Ltd. is a company based in Misgav, Israel, that specializes in the development of innovative devices for laparoscopic surgery. Founded in 2011, the company focuses on creating an inflatable balloon retractor designed to enhance surgical procedures. This retractor effectively and gently retracts abdominal organs, such as the intestines, thereby minimizing complications and shortening operating times. Additionally, it reduces the need for extra assistance during surgery, ultimately leading to lower costs and facilitating quicker patient recovery with minimal incisions. The LapSpace team combines extensive business expertise with medical knowledge, positioning the company as a key player in advancing laparoscopic techniques.

ApiFix Ltd. is a medical device company based in Misgav, Israel, specializing in the development of a minimally invasive scoliosis correction system designed for adolescents with Adolescent Idiopathic Scoliosis (AIS), particularly those classified as Lenke Type 1 or Type 5, with Cobb angles ranging from 35 to 55 degrees. Founded in 2011, ApiFix offers an innovative approach that contrasts with traditional scoliosis surgeries by utilizing a miniature ratchet mechanism to facilitate gradual corrections as the patient bends in the corrective direction. This system allows for a less invasive surgical intervention, coupled with a correction process that extends over several months, supported by specialized physical therapy. As of April 2020, ApiFix operates as a subsidiary of OrthoPediatrics Corp.

MitrAssist is a medical device company focused on addressing mitral valve regurgitation (MR) through an innovative and minimally invasive approach. The company has developed a proprietary mitral valve implant that complements the natural mitral valve rather than replacing or repairing it. This unique "valve-in-valve" technique enhances the functionality of the existing valve, providing an effective treatment option for patients suffering from MR. MitrAssist's implant is designed to address the challenges associated with MR, offering a solution that surpasses current minimally invasive alternatives. By prioritizing patient health and comfort, MitrAssist aims to significantly improve treatment outcomes for individuals with this condition.

Immunovative Therapies Ltd. is a biopharmaceutical company based in Jerusalem, Israel, focused on developing innovative immunotherapy products to treat cancer and infectious diseases in adult patients. Established in 2004, the company specializes in using living immune cells as active ingredients in its therapies. Key products include AlloStim, which utilizes activated T-Stim cells for infusion; CryoVax, an in-situ therapeutic cancer vaccine targeting disseminated metastatic tumors; CRCL, a source of patient-specific tumor antigens; and AlloVax, an individualized anti-cancer vaccine designed to educate the immune system during cancer remission to prevent recurrence. Immunovative Therapies develops treatment protocols for various conditions, including hematological malignancies, prostate cancer, breast cancer, glioblastoma multiforme, colorectal cancer with liver metastases, kidney cancer, and non-small cell lung cancer. The company's mission is to enhance patient quality of life and provide effective treatment options through its novel immunotherapeutic approaches.

InnoLap Surgical develops a device for scarless laparoscopic procedures. The device comprises a handle, thin 3 mm needle, and 5-10 mm detachable and replaceable operating heads. The company was founded in 2012 and is based in Misgav, Israel. As of September 30, 2013, InnoLap Surgical Ltd. operates as a subsidiary of Teleflex Incorporated.

Polytouch Medical is dedicated to advancing minimally invasive surgery through the development of innovative solutions for laparoscopic procedures, particularly in hernia repair. The company specializes in hernia mesh placement technologies, with its flagship product, PatchAssist, designed to facilitate the treatment of ventral hernias. By collaborating closely with physicians, Polytouch Medical focuses on enhancing mesh deployment and placement techniques, thereby enabling quicker treatment initiation and increasing the likelihood of successful outcomes for patients. The company prides itself on its dedicated workforce, medical advisors who translate ideas into practical applications, and board members who assist in bringing these products to market.

Nephera Ltd., established in 2008 and headquartered in Misgav, Israel, specializes in developing medical devices for treating kidney dysfunction associated with chronic health conditions. The company's flagship product is an implantable pulse generator designed to enhance and maintain kidney functionality in patients suffering from congestive heart failure (CHF). This device operates by modulating sympathetic nerve activity through electrical stimulation of the urinary tract, thereby preserving renal function and improving diuretic therapy outcomes during frequent hospitalizations.

Inspiro Medical Ltd. is a medical device company focused on creating an innovative inhalation platform that facilitates the delivery of both small molecules, including corticosteroids and beta agonists, and larger macromolecules, such as antibodies and vaccines. The company is actively conducting clinical trials involving its proprietary dry powder inhaler, Inspiromatic, specifically targeting children with asthma. Through its advanced technology, Inspiro Medical aims to enhance treatment options for respiratory diseases.

Stimatix GI is an early-stage startup founded in June 2009, operating under the Misgav Venture Accelerator with funding from the Office of the Chief Scientist. The company specializes in the development of innovative ostomy appliances, particularly its Artificial Ostomy Sphincter (AOS) product line, which includes the AOS-1000 and AOS-C2000. These unique colostomy devices enable voluntary bowel evacuation, providing users with greater control over their routines. Designed to be aesthetically pleasing and user-friendly, the AOS products effectively seal the stoma, addressing the common challenges associated with traditional adhesive bags. By offering a low-profile solution, Stimatix GI enhances the quality of life for individuals with stomas, restoring functions similar to those of a healthy anus and rectum while minimizing skin irritation and discomfort often associated with ostomy care.

ETView Medical Ltd. specializes in advanced airway management solutions by integrating continuous direct airway visualization with its medical products. The company has developed patented single-use single and double-lumen endotracheal tubes, which are equipped with a high-resolution video imaging system. These innovative tubes, such as the VivaSight SL and DL, feature a miniature camera and light source that assist medical professionals during difficult intubations. ETView Medical aims to enhance the safety and efficacy of airway management through its cutting-edge imaging technologies and related medical accessories.

The URINFO 2000 fluid monitoring system is the only feasible solution for the accurate, real-time, and continuous monitoring of urine output. The product is based on FlowSense’s patented optical flow sensing technology. URINFO2000 has been used in the critical care setting to optimize fluid and electrolyte balance, treat acute kidney injury, and prevent renal failure.

VivoText is a creative digital speech platform that specializes in expressive speech synthesis for the entertainment and media sectors. The company develops a text-to-speech engine that allows content creators to craft personalized and scalable audio content using virtual human voices. VivoText's technology enables users to maintain creative control over the emotional expression and nuances of the speech output, making it particularly valuable for industries such as publishing, gaming, and marketing. By providing advanced tools for narration, voiceover, and complex spoken content, VivoText empowers voice artists to create lifelike digital speech that meets individual preferences and enhances engagement with audiences.

LifeBond Ltd. is a developer and manufacturer of absorbable bio-surgical medical devices focused on tissue repair, aiming to enhance patient recovery and support the body's natural healing process. Founded in 2006 and based in Caesarea, Israel, the company offers a range of products, including the LifeSeal Surgical Sealant, which provides reinforcement to minimize post-operative complications such as staple-line leakage in various surgical procedures. Another key product, LifeMesh Self-Fixating Mesh, is designed for secure fixation during hernia repair, addressing post-surgical complications effectively. In addition to these products, LifeBond is engaged in the development of tissue adhesives and absorbable hemostats. Their innovative devices are designed to meet a variety of surgical needs and are available in markets including China, the United States, and Europe, although many products remain investigational and have not yet received market approval.

BioSight Ltd., established in 1999 and headquartered in Lod, Israel, is a biopharmaceutical company specializing in the development of innovative cancer-targeted pro-drugs. It focuses on creating non-toxic conjugates like its cytarabine-asparagine conjugate for treating acute myeloid leukemia patients worldwide. BioSight's proprietary technology, S2DOT™, enables targeted drug release inside cancer cells, minimizing systemic toxicity compared to conventional chemotherapy treatments.

Immunovative Therapies Ltd. is a biopharmaceutical company based in Jerusalem, Israel, focused on developing innovative immunotherapy products to treat cancer and infectious diseases in adult patients. Established in 2004, the company specializes in using living immune cells as active ingredients in its therapies. Key products include AlloStim, which utilizes activated T-Stim cells for infusion; CryoVax, an in-situ therapeutic cancer vaccine targeting disseminated metastatic tumors; CRCL, a source of patient-specific tumor antigens; and AlloVax, an individualized anti-cancer vaccine designed to educate the immune system during cancer remission to prevent recurrence. Immunovative Therapies develops treatment protocols for various conditions, including hematological malignancies, prostate cancer, breast cancer, glioblastoma multiforme, colorectal cancer with liver metastases, kidney cancer, and non-small cell lung cancer. The company's mission is to enhance patient quality of life and provide effective treatment options through its novel immunotherapeutic approaches.