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Cala Health, Inc. is a bioelectronic medicine company based in Burlingame, California, founded in 2013. The company specializes in developing wearable neuromodulation therapies aimed at treating chronic diseases. Its flagship product, Cala Trio, is a non-invasive prescription therapy designed to provide transient relief from hand tremors in adults with essential tremor. By integrating advancements in neuroscience and technology, Cala Health focuses on individualized peripheral nerve stimulation to enhance patient outcomes. In addition to its work on essential tremor, the company is also developing therapies for conditions such as Parkinson's disease, as well as exploring applications in psychiatry, cardiology, and autoimmune disorders.

TailorMed Medical Ltd., established in 2017 and based in Tel Aviv, Israel, specializes in health IT solutions. The company develops and provides financial navigation technology and systems, designed to streamline and automate financial processes for both patients and healthcare providers. Their offerings include TailorMed Financial Navigation, a platform to manage and automate financial processes; TailorMed Financial Insights, an analytics and reporting dashboard to track and measure key performance indicators; and TailorMed Pharmacy, a platform to simplify drug ordering, tracking, and billing based on patient treatment regimens.

Grin is a digital orthodontic platform designed to provide comprehensive teeth straightening solutions for patients of all types, connecting them with local orthodontists through their smart devices. The platform emphasizes responsible and accessible care, leveraging a network of trusted orthodontic specialists to deliver quality treatment aimed at achieving optimal smiles. Grin incorporates patent-pending technology in its Grin App and Grin Scope, which allows for remote monitoring of orthodontic progress and facilitates telemedicine consultations, thereby enhancing the convenience of the treatment journey. By enabling high-quality self-scans and virtual check-ins, Grin aims to improve patient outcomes while reducing chair time for orthodontic practitioners. Founded in 2019 by Dr. Adam Schulhof, Pamela Oren-Artzi, and Alon Lipnik, Grin operates from its bases in New York and Austin, focusing on blending modern technology with traditional orthodontic care.

Monogoto is a cloud-based cellular network provider that specializes in delivering global cellular connectivity alongside secure private LTE networks. Its API-driven Infrastructure-as-a-Service is designed to seamlessly integrate with existing enterprise IT infrastructure, offering hundreds of ready-to-use APIs. Monogoto's services cater to advanced use cases such as IoT, Private LTE, and 5G, ensuring that users can enjoy worldwide roaming capabilities and optimal continuous connectivity. The company provides full audit capabilities for network events, including anomaly detection and automated alerts, enhancing security and compliance. With a business model that eliminates capital expenditure and enables consumption on an "as-a-Service" basis, Monogoto's solution supports on-premise local breakout topologies for private networks, making it an enterprise-friendly option for organizations seeking reliable and efficient cellular connectivity. Its network spans globally, with public connectivity available in 180 countries.

Brightside Health, Inc. is a telemedicine platform based in San Francisco, California, focused on providing evidence-based mental health treatments for anxiety and depression. Established in 2017, the company offers a mobile application that facilitates personalized treatment experiences through video consultations, messaging, and ongoing support, including medication delivery. Brightside Health employs precision psychiatry and clinically proven therapeutic approaches to evaluate and monitor patients' mental health. Its platform provides tools and resources for lifestyle management, therapy referrals, and progress tracking, enabling individuals to access quality care and improve their well-being. The company was previously known as Good Measure, Inc. before rebranding in February 2018.

BioProtect Ltd. is an international medical device startup founded in 2004 and headquartered in Israel, with subsidiaries in Germany and the United States. The company specializes in the development and commercialization of biodegradable balloon spacers designed to protect normal tissue during radiation therapy for cancer. Its flagship product, the ProSpace balloon spacer, has received CE marking and demonstrates superior efficacy and safety in safeguarding the rectum during prostate cancer radiation therapy. By creating a temporary separation between the rectum and targeted tissues, BioProtect's technology significantly reduces the risk of serious and chronic side effects associated with radiation treatment while enhancing tumor control. Additionally, the company's platform of biodegradable implantable balloons addresses a variety of unmet clinical needs in the growing radiotherapy spacers market.

FeelBetter is a healthcare optimization platform founded in 2018 and based in Tel Aviv, Israel. The company focuses on value-based models to identify at-risk patients and appropriate interventions. Its platform enhances financial and clinical outcomes by analyzing individual patients' health journeys and diagnosing necessary interventions before deterioration occurs. By delivering personalized data and actionable insights, FeelBetter enables healthcare organizations to improve patient outcomes and overall business results.

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FEMSelect Inc., founded in 2012, is a medical device company focused on improving women's health through innovative surgical solutions. Based in Newark, Delaware, FEMSelect develops minimally-invasive and mesh-free systems for pelvic floor ligament fixation. Their flagship product, EnPlace, is designed to treat pelvic organ prolapse (POP) by precisely guiding, inserting, and deploying an anchor unit through the vaginal wall to stabilize the pelvic floor ligament. The procedure typically takes around 30 minutes and does not require overnight hospital stays or result in significant scarring.

Future Family, Inc. is a subscription-based fertility company founded in 2016 and headquartered in San Francisco, California. It provides comprehensive healthcare solutions for individuals and couples navigating fertility challenges, offering plans that cover all associated costs. The company's services include personalized fertility planning, clinic matching, and a dedicated nurse concierge, ensuring 24/7 access to a care team. Future Family specializes in on-demand medical support for procedures such as in vitro fertilization (IVF) and egg freezing, and it features a digital health platform for managing fertility care. By combining financial assistance with expert guidance, Future Family aims to deliver a stress-free fertility experience for its clients.

PayGround, Inc. is a technology company that specializes in developing billing and payment software solutions for the healthcare industry. Founded in 2018 and headquartered in Chandler, Arizona, PayGround provides a cloud-based platform that allows healthcare providers to efficiently manage patient accounts, create and send invoices, and track billing analytics. The platform simplifies the payment process by enabling providers to upload accounts receivable and initiate digital payment requests through various channels, including email, text, and U.S. Mail. Patients benefit from the service by being able to view and pay their bills quickly, facilitating a smoother billing experience. By streamlining financial interactions between healthcare providers and patients, PayGround aims to reduce costs and eliminate the complexities associated with managing multiple billing accounts.

Brightside Health, Inc. is a telemedicine platform based in San Francisco, California, focused on providing evidence-based mental health treatments for anxiety and depression. Established in 2017, the company offers a mobile application that facilitates personalized treatment experiences through video consultations, messaging, and ongoing support, including medication delivery. Brightside Health employs precision psychiatry and clinically proven therapeutic approaches to evaluate and monitor patients' mental health. Its platform provides tools and resources for lifestyle management, therapy referrals, and progress tracking, enabling individuals to access quality care and improve their well-being. The company was previously known as Good Measure, Inc. before rebranding in February 2018.

Day Zero Diagnostics Inc. is an innovative company focused on transforming infectious disease diagnostics through advanced sequencing technologies. Based in Boston, Massachusetts, the company has developed a rapid diagnostic system that identifies bacterial species and their antibiotic resistance profiles directly from clinical samples. Key technologies include Blood2Bac, which enriches bacterial DNA, and BacDetect, allowing for swift detection of bacterial DNA. Additionally, the company employs machine learning algorithms for genomic antibiotic susceptibility testing and maintains a comprehensive microbial database that integrates genomic sequencing data with resistance profiles. By enabling rapid and accurate diagnoses, Day Zero Diagnostics aims to address critical needs in managing bloodstream infections and sepsis, reducing the time for diagnosis from days to hours and improving patient outcomes through targeted treatments.

V-Wave Ltd. is a medical technology company specializing in the development of percutaneous implantable therapeutic devices for patients with chronic heart failure. Established in 2009 and headquartered in Caesarea, Israel, with additional offices in the United States, V-Wave aims to address the needs of patients who continue to experience severe symptoms or require hospitalization despite optimal medical treatment. The company's flagship product is the V-Wave Shunt, a biocompatible, inter-atrial unidirectional implant designed to alleviate symptoms related to chronic heart failure by regulating Left Atrial Pressure. This innovative device seeks to improve patients' quality of life by reducing hospitalizations, enhancing exercise capacity, and ultimately providing symptomatic relief. V-Wave's team comprises experienced engineers and medical scientists dedicated to advancing the field of cardiovascular devices.

Monogoto is a cloud-based cellular network provider that specializes in delivering global cellular connectivity alongside secure private LTE networks. Its API-driven Infrastructure-as-a-Service is designed to seamlessly integrate with existing enterprise IT infrastructure, offering hundreds of ready-to-use APIs. Monogoto's services cater to advanced use cases such as IoT, Private LTE, and 5G, ensuring that users can enjoy worldwide roaming capabilities and optimal continuous connectivity. The company provides full audit capabilities for network events, including anomaly detection and automated alerts, enhancing security and compliance. With a business model that eliminates capital expenditure and enables consumption on an "as-a-Service" basis, Monogoto's solution supports on-premise local breakout topologies for private networks, making it an enterprise-friendly option for organizations seeking reliable and efficient cellular connectivity. Its network spans globally, with public connectivity available in 180 countries.

TailorMed Medical Ltd., established in 2017 and based in Tel Aviv, Israel, specializes in health IT solutions. The company develops and provides financial navigation technology and systems, designed to streamline and automate financial processes for both patients and healthcare providers. Their offerings include TailorMed Financial Navigation, a platform to manage and automate financial processes; TailorMed Financial Insights, an analytics and reporting dashboard to track and measure key performance indicators; and TailorMed Pharmacy, a platform to simplify drug ordering, tracking, and billing based on patient treatment regimens.

Brightside Health, Inc. is a telemedicine platform based in San Francisco, California, focused on providing evidence-based mental health treatments for anxiety and depression. Established in 2017, the company offers a mobile application that facilitates personalized treatment experiences through video consultations, messaging, and ongoing support, including medication delivery. Brightside Health employs precision psychiatry and clinically proven therapeutic approaches to evaluate and monitor patients' mental health. Its platform provides tools and resources for lifestyle management, therapy referrals, and progress tracking, enabling individuals to access quality care and improve their well-being. The company was previously known as Good Measure, Inc. before rebranding in February 2018.

Grin is a digital orthodontic platform designed to provide comprehensive teeth straightening solutions for patients of all types, connecting them with local orthodontists through their smart devices. The platform emphasizes responsible and accessible care, leveraging a network of trusted orthodontic specialists to deliver quality treatment aimed at achieving optimal smiles. Grin incorporates patent-pending technology in its Grin App and Grin Scope, which allows for remote monitoring of orthodontic progress and facilitates telemedicine consultations, thereby enhancing the convenience of the treatment journey. By enabling high-quality self-scans and virtual check-ins, Grin aims to improve patient outcomes while reducing chair time for orthodontic practitioners. Founded in 2019 by Dr. Adam Schulhof, Pamela Oren-Artzi, and Alon Lipnik, Grin operates from its bases in New York and Austin, focusing on blending modern technology with traditional orthodontic care.

EyeYon Medical is an Israeli startup based in Jerusalem, developing innovative medical devices focused on treating corneal edema. The company's flagship product, Hyper-CL, is a hyperosmotic contact lens designed to extract fluids from the cornea through osmosis, improving vision and relieving pain. Additionally, EyeYon Medical has developed DSPEK, an artificial endothelial layer intended to replace injured tissue that can cause corneal edema. Founded by Dr. Daphna Ofer, Dr. Arie Marcovich, and Nahum Ferera, the company operates within the Van Leer Technology Incubator.

BurnAlong, Inc. is a technology company that has developed an online fitness and wellness video application designed to enhance personal well-being through social motivation and tailored fitness experiences. Founded in 2016 and headquartered in Pikesville, Maryland, BurnAlong allows users to participate in health and fitness classes via video feed, connecting them with friends, fitness instructors, and a broader community. The platform employs machine learning to provide personalized recommendations, catering to a diverse audience that includes corporate employers, municipalities, insurers, individuals, and senior citizens. By facilitating engaging wellness classes, BurnAlong aims to help individuals achieve their health and wellness goals while promoting a positive culture within organizations.

PayGround, Inc. is a technology company that specializes in developing billing and payment software solutions for the healthcare industry. Founded in 2018 and headquartered in Chandler, Arizona, PayGround provides a cloud-based platform that allows healthcare providers to efficiently manage patient accounts, create and send invoices, and track billing analytics. The platform simplifies the payment process by enabling providers to upload accounts receivable and initiate digital payment requests through various channels, including email, text, and U.S. Mail. Patients benefit from the service by being able to view and pay their bills quickly, facilitating a smoother billing experience. By streamlining financial interactions between healthcare providers and patients, PayGround aims to reduce costs and eliminate the complexities associated with managing multiple billing accounts.

Medisafe is a digital patient engagement platform that focuses on enhancing medication management and improving patient adherence. By utilizing billions of data points, the platform personalizes patient interactions and addresses the significant challenges associated with medication non-adherence. Medisafe’s solutions have been shown to increase adherence rates by up to 20%, supported by extensive studies involving tens of thousands of patients. The platform is designed to engage patients throughout their medication journey while providing valuable insights into their behavior patterns, which are crucial for enhancing the overall patient experience. With nearly 5 million registered users across various devices, Medisafe has recorded over 2 billion medication doses and has received high ratings from users, averaging 4.7 out of 5 stars. The company has garnered several accolades, including recognition as a Gartner Cool Vendor and being named one of the Most Innovative in Healthcare by Fast Company. Medisafe’s mission is to empower patients and facilitate better communication between them and their healthcare providers, ultimately improving health outcomes.

Genoox, Ltd. is a company that develops a cloud-based platform dedicated to managing and analyzing genomic data. Founded in 2014 by Amir Trabelsi and Moshe Einhorn, the company is headquartered in Palo Alto, California. Genoox's platform harnesses artificial intelligence and machine-learning algorithms to translate complex genetic information into actionable clinical insights, thereby facilitating genetic diagnostics and personalized treatment options for patients. The platform connects clinicians, genetic counselors, and healthcare organizations, creating a collaborative network that enhances the sharing of genetic insights. With over 1,700 health organizations, hospitals, and medical facilities utilizing its services across 44 markets globally, Genoox aims to establish the largest real-world evidence network of genomic and clinical data, ultimately improving patient outcomes through more effective and efficient data handling.

V-Wave Ltd. is a medical technology company specializing in the development of percutaneous implantable therapeutic devices for patients with chronic heart failure. Established in 2009 and headquartered in Caesarea, Israel, with additional offices in the United States, V-Wave aims to address the needs of patients who continue to experience severe symptoms or require hospitalization despite optimal medical treatment. The company's flagship product is the V-Wave Shunt, a biocompatible, inter-atrial unidirectional implant designed to alleviate symptoms related to chronic heart failure by regulating Left Atrial Pressure. This innovative device seeks to improve patients' quality of life by reducing hospitalizations, enhancing exercise capacity, and ultimately providing symptomatic relief. V-Wave's team comprises experienced engineers and medical scientists dedicated to advancing the field of cardiovascular devices.

BioProtect Ltd. is an international medical device startup founded in 2004 and headquartered in Israel, with subsidiaries in Germany and the United States. The company specializes in the development and commercialization of biodegradable balloon spacers designed to protect normal tissue during radiation therapy for cancer. Its flagship product, the ProSpace balloon spacer, has received CE marking and demonstrates superior efficacy and safety in safeguarding the rectum during prostate cancer radiation therapy. By creating a temporary separation between the rectum and targeted tissues, BioProtect's technology significantly reduces the risk of serious and chronic side effects associated with radiation treatment while enhancing tumor control. Additionally, the company's platform of biodegradable implantable balloons addresses a variety of unmet clinical needs in the growing radiotherapy spacers market.

TuneFork is a company specializing in audio personalization technology software aimed at delivering an optimal hearing experience across various devices. The software guides users through a clinically accurate self-test to create a personalized Audio Profile, which characterizes individual hearing capabilities. This profile is then used to tailor precise audio filters, ensuring the best possible match between the user's sound system and their unique hearing characteristics. TuneFork can be integrated into any operating or network system to optimize all types of audio content, including phone calls, music, video, voice messages, and alerts. The technology is particularly beneficial for smartphones, which are widely used for communication, entertainment, and social networking. By enhancing the audio experience, TuneFork not only improves sound quality but also helps mitigate potential hearing damage from unbalanced audio.

Latica, formerly known as Lynx.MD, is a healthcare data company established in 2019 that focuses on transforming medical research and patient care through a secure data ecosystem. The company offers a platform that enables life sciences organizations, healthcare providers, and researchers to access and collaborate on clinical and operational data. By employing advanced technologies such as artificial intelligence and data analytics, Latica aims to unlock the potential of previously siloed healthcare data, facilitating meaningful advancements in medical research while prioritizing patient privacy and security. The platform fosters collaboration among various stakeholders in the healthcare sector, providing actionable insights that enhance outcomes for patients and improve the efficiency of healthcare delivery.

TailorMed Medical Ltd., established in 2017 and based in Tel Aviv, Israel, specializes in health IT solutions. The company develops and provides financial navigation technology and systems, designed to streamline and automate financial processes for both patients and healthcare providers. Their offerings include TailorMed Financial Navigation, a platform to manage and automate financial processes; TailorMed Financial Insights, an analytics and reporting dashboard to track and measure key performance indicators; and TailorMed Pharmacy, a platform to simplify drug ordering, tracking, and billing based on patient treatment regimens.

Cala Health, Inc. is a bioelectronic medicine company based in Burlingame, California, founded in 2013. The company specializes in developing wearable neuromodulation therapies aimed at treating chronic diseases. Its flagship product, Cala Trio, is a non-invasive prescription therapy designed to provide transient relief from hand tremors in adults with essential tremor. By integrating advancements in neuroscience and technology, Cala Health focuses on individualized peripheral nerve stimulation to enhance patient outcomes. In addition to its work on essential tremor, the company is also developing therapies for conditions such as Parkinson's disease, as well as exploring applications in psychiatry, cardiology, and autoimmune disorders.

TailorMed Medical Ltd., established in 2017 and based in Tel Aviv, Israel, specializes in health IT solutions. The company develops and provides financial navigation technology and systems, designed to streamline and automate financial processes for both patients and healthcare providers. Their offerings include TailorMed Financial Navigation, a platform to manage and automate financial processes; TailorMed Financial Insights, an analytics and reporting dashboard to track and measure key performance indicators; and TailorMed Pharmacy, a platform to simplify drug ordering, tracking, and billing based on patient treatment regimens.

Day Zero Diagnostics Inc. is an innovative company focused on transforming infectious disease diagnostics through advanced sequencing technologies. Based in Boston, Massachusetts, the company has developed a rapid diagnostic system that identifies bacterial species and their antibiotic resistance profiles directly from clinical samples. Key technologies include Blood2Bac, which enriches bacterial DNA, and BacDetect, allowing for swift detection of bacterial DNA. Additionally, the company employs machine learning algorithms for genomic antibiotic susceptibility testing and maintains a comprehensive microbial database that integrates genomic sequencing data with resistance profiles. By enabling rapid and accurate diagnoses, Day Zero Diagnostics aims to address critical needs in managing bloodstream infections and sepsis, reducing the time for diagnosis from days to hours and improving patient outcomes through targeted treatments.

Latica, formerly known as Lynx.MD, is a healthcare data company established in 2019 that focuses on transforming medical research and patient care through a secure data ecosystem. The company offers a platform that enables life sciences organizations, healthcare providers, and researchers to access and collaborate on clinical and operational data. By employing advanced technologies such as artificial intelligence and data analytics, Latica aims to unlock the potential of previously siloed healthcare data, facilitating meaningful advancements in medical research while prioritizing patient privacy and security. The platform fosters collaboration among various stakeholders in the healthcare sector, providing actionable insights that enhance outcomes for patients and improve the efficiency of healthcare delivery.

Genoox, Ltd. is a company that develops a cloud-based platform dedicated to managing and analyzing genomic data. Founded in 2014 by Amir Trabelsi and Moshe Einhorn, the company is headquartered in Palo Alto, California. Genoox's platform harnesses artificial intelligence and machine-learning algorithms to translate complex genetic information into actionable clinical insights, thereby facilitating genetic diagnostics and personalized treatment options for patients. The platform connects clinicians, genetic counselors, and healthcare organizations, creating a collaborative network that enhances the sharing of genetic insights. With over 1,700 health organizations, hospitals, and medical facilities utilizing its services across 44 markets globally, Genoox aims to establish the largest real-world evidence network of genomic and clinical data, ultimately improving patient outcomes through more effective and efficient data handling.

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V-Wave Ltd. is a medical technology company specializing in the development of percutaneous implantable therapeutic devices for patients with chronic heart failure. Established in 2009 and headquartered in Caesarea, Israel, with additional offices in the United States, V-Wave aims to address the needs of patients who continue to experience severe symptoms or require hospitalization despite optimal medical treatment. The company's flagship product is the V-Wave Shunt, a biocompatible, inter-atrial unidirectional implant designed to alleviate symptoms related to chronic heart failure by regulating Left Atrial Pressure. This innovative device seeks to improve patients' quality of life by reducing hospitalizations, enhancing exercise capacity, and ultimately providing symptomatic relief. V-Wave's team comprises experienced engineers and medical scientists dedicated to advancing the field of cardiovascular devices.

Vi Labs is a prominent enterprise AI platform focused on the healthcare sector. The company provides advanced technologies that help large health organizations enhance member health outcomes while improving financial performance. By utilizing extensive household-level data and sophisticated predictive engagement frameworks, Vi Labs enables these organizations to reduce customer acquisition costs and maximize member lifetime value. This approach not only improves the health outcomes of members but also enhances the overall income potential for health enterprises. Through its innovative solutions, Vi Labs positions itself as a vital partner for health organizations aiming to leverage data and AI effectively.

CathWorks Ltd. is a medical technology company that specializes in enhancing percutaneous coronary intervention (PCI) therapy decisions through its advanced computational science platform. Founded in 2013 and headquartered in Kfar-Saba, Israel, with an additional office in the United States, CathWorks aims to transform coronary angiography from subjective visual assessments into an objective decision-making tool. The company's flagship product, CathWorks FFRangio, is a non-invasive device that provides multi-vessel physiologic measurements, allowing physicians to optimize and confirm PCI therapy decisions during procedures. By leveraging functional flow reserve (FFR) data and automated algorithms, CathWorks enhances the use of coronary angiography data, promoting measurement-based medicine and improving operational efficiency in cath labs.

Colospan Ltd is a clinical-stage medical device company based in Kfar Saba, Israel, specializing in healthcare equipment for colorectal surgeries. Established in 2010, Colospan develops proprietary technology aimed at preventing anastomotic leaks and the need for diverting colonic stomas after intestinal surgeries. The company’s lead product is a single-use, temporary intraluminal bypass device designed to reduce contact between fecal matter and the anastomotic site, thereby mitigating the complications associated with such leaks. This innovative device is intended to prevent or delay the need for colostomy after surgeries performed for severe intestinal inflammatory diseases and colorectal cancer. Colospan’s technology seeks to enhance patient recovery by reducing the risk of life-threatening symptoms associated with clinical anastomotic leaks and minimizing post-operative complications, ultimately supporting the well-being of patients following significant surgical procedures.

Colospan Ltd is a clinical-stage medical device company based in Kfar Saba, Israel, specializing in healthcare equipment for colorectal surgeries. Established in 2010, Colospan develops proprietary technology aimed at preventing anastomotic leaks and the need for diverting colonic stomas after intestinal surgeries. The company’s lead product is a single-use, temporary intraluminal bypass device designed to reduce contact between fecal matter and the anastomotic site, thereby mitigating the complications associated with such leaks. This innovative device is intended to prevent or delay the need for colostomy after surgeries performed for severe intestinal inflammatory diseases and colorectal cancer. Colospan’s technology seeks to enhance patient recovery by reducing the risk of life-threatening symptoms associated with clinical anastomotic leaks and minimizing post-operative complications, ultimately supporting the well-being of patients following significant surgical procedures.

ZingBox, established in 2014 and headquartered in Mountain View, California, specializes in enterprise Internet of Things (IoT) security. It offers a real-time IoT security solution that discovers and protects connected equipment, safeguarding against cyber and insider threats. Primarily serving the healthcare and manufacturing industries, ZingBox's platform detects anomalous behavior, maps networks, and generates risk profiles. It operates as a subsidiary of Palo Alto Networks, Inc.

EyeYon Medical is an Israeli startup based in Jerusalem, developing innovative medical devices focused on treating corneal edema. The company's flagship product, Hyper-CL, is a hyperosmotic contact lens designed to extract fluids from the cornea through osmosis, improving vision and relieving pain. Additionally, EyeYon Medical has developed DSPEK, an artificial endothelial layer intended to replace injured tissue that can cause corneal edema. Founded by Dr. Daphna Ofer, Dr. Arie Marcovich, and Nahum Ferera, the company operates within the Van Leer Technology Incubator.

Medisafe is a digital patient engagement platform that focuses on enhancing medication management and improving patient adherence. By utilizing billions of data points, the platform personalizes patient interactions and addresses the significant challenges associated with medication non-adherence. Medisafe’s solutions have been shown to increase adherence rates by up to 20%, supported by extensive studies involving tens of thousands of patients. The platform is designed to engage patients throughout their medication journey while providing valuable insights into their behavior patterns, which are crucial for enhancing the overall patient experience. With nearly 5 million registered users across various devices, Medisafe has recorded over 2 billion medication doses and has received high ratings from users, averaging 4.7 out of 5 stars. The company has garnered several accolades, including recognition as a Gartner Cool Vendor and being named one of the Most Innovative in Healthcare by Fast Company. Medisafe’s mission is to empower patients and facilitate better communication between them and their healthcare providers, ultimately improving health outcomes.

OrthoSpace Ltd. is an Israeli company that specializes in the development and commercialization of biodegradable balloon systems designed for the orthopedic market, specifically targeting rotator cuff syndrome. Founded in 2009 and based in Caesarea, the company focuses on creating effective solutions that alleviate pain, improve patients' range of motion, and preserve bone and joint structures. Its flagship product, InSpace™, has received CE marking and is marketed in Europe. This innovative balloon system mimics the function of the original bursa, acting as a spacer between the acromion and the humeral head, which facilitates smooth movement and reduces friction between the bones. OrthoSpace operates under the umbrella of Stryker Corporation, enhancing its capabilities in delivering advanced orthopedic solutions.

Vi Labs is a prominent enterprise AI platform focused on the healthcare sector. The company provides advanced technologies that help large health organizations enhance member health outcomes while improving financial performance. By utilizing extensive household-level data and sophisticated predictive engagement frameworks, Vi Labs enables these organizations to reduce customer acquisition costs and maximize member lifetime value. This approach not only improves the health outcomes of members but also enhances the overall income potential for health enterprises. Through its innovative solutions, Vi Labs positions itself as a vital partner for health organizations aiming to leverage data and AI effectively.

V-Wave Ltd. is a medical technology company specializing in the development of percutaneous implantable therapeutic devices for patients with chronic heart failure. Established in 2009 and headquartered in Caesarea, Israel, with additional offices in the United States, V-Wave aims to address the needs of patients who continue to experience severe symptoms or require hospitalization despite optimal medical treatment. The company's flagship product is the V-Wave Shunt, a biocompatible, inter-atrial unidirectional implant designed to alleviate symptoms related to chronic heart failure by regulating Left Atrial Pressure. This innovative device seeks to improve patients' quality of life by reducing hospitalizations, enhancing exercise capacity, and ultimately providing symptomatic relief. V-Wave's team comprises experienced engineers and medical scientists dedicated to advancing the field of cardiovascular devices.

6over6 is a digital healthcare company that has developed a platform allowing users to conduct their own eye vision tests using their smartphones. By integrating essential optometric tools into a mobile application, the company enables users to obtain accurate measurements of refractive errors, which are necessary for eyeglasses and contact lens prescriptions. Their product, GlassesOn, is registered as a Class 1 Exempt Medical Device with the FDA, emphasizing the company's commitment to safety and regulatory compliance. While GlassesOn facilitates effective vision assessment, it does not offer medical advice and is not a substitute for a comprehensive eye health examination. Through this innovative approach, 6over6 aims to enhance accessibility to vision care for a broader audience.

MST Medical Surgery Technologies Ltd., founded in 2005 and headquartered in Tel Aviv, Israel, with an additional office in Apollo Beach, Florida, specializes in developing advanced image analysis software for the healthcare industry. The company is a leader in surgical analytics, focusing on medical robotics and computer-assisted surgery. Its flagship product, AutoLap, is an innovative robotic image-guided laparoscope positioning system that enhances the precision and control of surgical procedures by providing real-time guidance based on the surgeon's movements. Additionally, MST offers Surgical Training Analytics (STA), a tool designed to capture images from actual surgical procedures, aiding in the training of new surgeons. By leveraging advanced visualization, artificial intelligence, and machine learning, MST aims to transform the operating room with automated, data-driven solutions that improve outcomes for both surgeons and patients.

OrthoSpace Ltd. is an Israeli company that specializes in the development and commercialization of biodegradable balloon systems designed for the orthopedic market, specifically targeting rotator cuff syndrome. Founded in 2009 and based in Caesarea, the company focuses on creating effective solutions that alleviate pain, improve patients' range of motion, and preserve bone and joint structures. Its flagship product, InSpace™, has received CE marking and is marketed in Europe. This innovative balloon system mimics the function of the original bursa, acting as a spacer between the acromion and the humeral head, which facilitates smooth movement and reduces friction between the bones. OrthoSpace operates under the umbrella of Stryker Corporation, enhancing its capabilities in delivering advanced orthopedic solutions.

Angioslide, Ltd. is a medical device company established in 2005 and headquartered in Natanya, Israel, with additional subsidiaries in Karlsruhe, Germany, and Edina, Minnesota. The company specializes in developing innovative angioplasty products, notably the Angioslide eXtra balloon catheter, which serves both as a stand-alone balloon for angioplasty and as a device for debris removal. Its proprietary Embolic Capture Angioplasty™ technology allows physicians to capture and eliminate embolic particles, chronic thrombus, and atherosclerotic plaque debris during angioplasty procedures. Angioslide focuses on addressing the needs of various markets, including peripheral artery, lower limb artery, carotid, and coronary artery diseases.

EyeYon Medical is an Israeli startup based in Jerusalem, developing innovative medical devices focused on treating corneal edema. The company's flagship product, Hyper-CL, is a hyperosmotic contact lens designed to extract fluids from the cornea through osmosis, improving vision and relieving pain. Additionally, EyeYon Medical has developed DSPEK, an artificial endothelial layer intended to replace injured tissue that can cause corneal edema. Founded by Dr. Daphna Ofer, Dr. Arie Marcovich, and Nahum Ferera, the company operates within the Van Leer Technology Incubator.

Medisafe is a digital patient engagement platform that focuses on enhancing medication management and improving patient adherence. By utilizing billions of data points, the platform personalizes patient interactions and addresses the significant challenges associated with medication non-adherence. Medisafe’s solutions have been shown to increase adherence rates by up to 20%, supported by extensive studies involving tens of thousands of patients. The platform is designed to engage patients throughout their medication journey while providing valuable insights into their behavior patterns, which are crucial for enhancing the overall patient experience. With nearly 5 million registered users across various devices, Medisafe has recorded over 2 billion medication doses and has received high ratings from users, averaging 4.7 out of 5 stars. The company has garnered several accolades, including recognition as a Gartner Cool Vendor and being named one of the Most Innovative in Healthcare by Fast Company. Medisafe’s mission is to empower patients and facilitate better communication between them and their healthcare providers, ultimately improving health outcomes.

BioGaming is a company focused on enhancing rehabilitation outcomes through innovative technology. It has developed an at-home virtual reality exercise platform that gamifies physiotherapy, making the rehabilitation process more engaging for patients. The platform integrates motion analysis systems with clinically developed exercise routines, immersing patients in a virtual environment where therapy becomes more enjoyable. This approach enables physical therapists to prescribe exercise programs that are transformed into interactive games while monitoring patient performance remotely. Using advanced machine learning algorithms, BioGaming generates detailed quantitative and qualitative reports that help both patients and therapists understand progress, ensuring a comprehensive and effective rehabilitation experience.

Cardiva Medical, Inc. is a medical device company based in Santa Clara, California, specializing in innovative vascular access management products that facilitate the healing process following percutaneous catheterization procedures. Founded in 2002, the company develops and markets several key products, including the VASCADE VCS, an extravascular and bioabsorbable femoral access closure system that promotes rapid hemostasis while reducing complications for patients. Additionally, Cardiva offers the Cardiva CATALYST, a manual compression assistance device that enhances coagulation and provides temporary hemostasis. The company also manufactures the VASCADE MVP, designed for multi-site venous closure in electrophysiology procedures. Cardiva Medical primarily serves physicians and cardiac centers across the United States, focusing on transforming vascular closure to benefit patients and healthcare providers.

Apica Cardiovascular is a pre-revenue medical device company specializing in a technology for accessing and closing the heart's apex and peripheral vascular system. This technology standardizes access and closure for large bore therapeutic devices without blood loss, enabling minimally invasive surgical or percutaneous procedures on the beating heart. It has applications in Transcatheter Heart Valves (TAVI), Abdominal Aortic Aneurysm (AAA) repair, and Left Ventricular Assist Device (LVAD) implantation. After successful animal and cadaver model testing, the technology is now advancing towards initial clinical trials.

Medisafe is a digital patient engagement platform that focuses on enhancing medication management and improving patient adherence. By utilizing billions of data points, the platform personalizes patient interactions and addresses the significant challenges associated with medication non-adherence. Medisafe’s solutions have been shown to increase adherence rates by up to 20%, supported by extensive studies involving tens of thousands of patients. The platform is designed to engage patients throughout their medication journey while providing valuable insights into their behavior patterns, which are crucial for enhancing the overall patient experience. With nearly 5 million registered users across various devices, Medisafe has recorded over 2 billion medication doses and has received high ratings from users, averaging 4.7 out of 5 stars. The company has garnered several accolades, including recognition as a Gartner Cool Vendor and being named one of the Most Innovative in Healthcare by Fast Company. Medisafe’s mission is to empower patients and facilitate better communication between them and their healthcare providers, ultimately improving health outcomes.

Angioslide, Ltd. is a medical device company established in 2005 and headquartered in Natanya, Israel, with additional subsidiaries in Karlsruhe, Germany, and Edina, Minnesota. The company specializes in developing innovative angioplasty products, notably the Angioslide eXtra balloon catheter, which serves both as a stand-alone balloon for angioplasty and as a device for debris removal. Its proprietary Embolic Capture Angioplasty™ technology allows physicians to capture and eliminate embolic particles, chronic thrombus, and atherosclerotic plaque debris during angioplasty procedures. Angioslide focuses on addressing the needs of various markets, including peripheral artery, lower limb artery, carotid, and coronary artery diseases.

Cardiva Medical, Inc. is a medical device company based in Santa Clara, California, specializing in innovative vascular access management products that facilitate the healing process following percutaneous catheterization procedures. Founded in 2002, the company develops and markets several key products, including the VASCADE VCS, an extravascular and bioabsorbable femoral access closure system that promotes rapid hemostasis while reducing complications for patients. Additionally, Cardiva offers the Cardiva CATALYST, a manual compression assistance device that enhances coagulation and provides temporary hemostasis. The company also manufactures the VASCADE MVP, designed for multi-site venous closure in electrophysiology procedures. Cardiva Medical primarily serves physicians and cardiac centers across the United States, focusing on transforming vascular closure to benefit patients and healthcare providers.

FEMSelect Inc., founded in 2012, is a medical device company focused on improving women's health through innovative surgical solutions. Based in Newark, Delaware, FEMSelect develops minimally-invasive and mesh-free systems for pelvic floor ligament fixation. Their flagship product, EnPlace, is designed to treat pelvic organ prolapse (POP) by precisely guiding, inserting, and deploying an anchor unit through the vaginal wall to stabilize the pelvic floor ligament. The procedure typically takes around 30 minutes and does not require overnight hospital stays or result in significant scarring.