Tybourne Capital Management

Forte Biosciences is a biotechnology company specializing in dermatology and biopharmaceuticals. The company's lead product, FB-401, is a topically applied live biotherapeutic designed to treat inflammatory skin diseases, developed in collaboration with the National Institutes of Health and the National Institute of Allergy and Infectious Diseases. Additionally, Forte Biosciences is advancing another product candidate, FB-102, which is a proprietary therapeutic molecule aimed at addressing a range of autoimmune conditions, including graft-versus-host disease, vitiligo, and alopecia areata. The company is currently in the preclinical trial stage for FB-102, reflecting its commitment to developing innovative treatments for dermatological and autoimmune disorders.

SkyCell AG is a Swiss company that designs and manufactures temperature-controlled containers specifically for the pharmaceutical industry. Established in 2013 and headquartered in Zurich, SkyCell focuses on providing safe and sustainable shipping solutions for temperature-sensitive goods. Its product lineup includes various models such as SkyCell 2500C, SkyCell 2500CRT, SkyCell 1500C, SkyCell 1500CRT, SkyCell 770C, and SkyCell 770CRT. Each container is equipped with Internet of Things (IoT) sensors that connect to the company's data cloud, allowing for real-time monitoring and intervention to ensure optimal conditions during transport. SkyCell's innovative approach combines hardware, software, and data analytics to enhance supply chain efficiency while minimizing temperature excursions and reducing carbon emissions. The company's software, built on blockchain technology, provides comprehensive visibility of shipments, enabling pharmaceutical companies to manage logistical challenges effectively.

Forte Biosciences is a biotechnology company specializing in dermatology and biopharmaceuticals. The company's lead product, FB-401, is a topically applied live biotherapeutic designed to treat inflammatory skin diseases, developed in collaboration with the National Institutes of Health and the National Institute of Allergy and Infectious Diseases. Additionally, Forte Biosciences is advancing another product candidate, FB-102, which is a proprietary therapeutic molecule aimed at addressing a range of autoimmune conditions, including graft-versus-host disease, vitiligo, and alopecia areata. The company is currently in the preclinical trial stage for FB-102, reflecting its commitment to developing innovative treatments for dermatological and autoimmune disorders.

Clove Dental operates a network of multi-specialty dental clinics that provide a wide range of professional oral healthcare services. With over 350 clinics and a patient base exceeding 1 million each month, Clove Dental specializes in various treatments including endodontics, periodontics, orthodontics, prosthodontics, cosmetic dentistry, pediatric care, and oral and maxillofacial surgery. The company is committed to high standards of hygiene, clinic safety, and customer service, employing more than 800 dentists and utilizing advanced equipment and pain-management technologies to enhance patient experiences.

Asuene is a company focused on renewable power retail services that facilitate local production and consumption of energy. Additionally, it has developed a carbon management platform aimed at assisting organizations in tracking, managing, and reporting their greenhouse gas emissions and other environmental impacts. Utilizing artificial intelligence, the platform integrates various data sources to collect emissions information and formulate strategies for reducing pollutants over time. This enables organizations to effectively manage their environmental footprint, comply with regulatory requirements, and work towards their sustainability objectives.

Acelyrin is a late-stage clinical biopharmaceutical company dedicated to advancing new treatment options for patients. The company specializes in identifying, acquiring, and accelerating the development and commercialization of promising drug candidates. By leveraging its expertise, Acelyrin aims to rapidly bring transformative medicines to market, ultimately improving patient outcomes and quality of life.

Kopi Kenangan is a grab-and-go coffee chain based in Indonesia that aims to meet the growing demand for fresh coffee beverages in a country with low per capita coffee consumption, despite being one of the world's largest coffee exporters. The company focuses on providing authentic coffee blends sourced from various regions in Indonesia, complemented by organic palm sugar to enhance flavor. Its business model includes order-and-pickup and delivery options, allowing customers convenient access to a diverse range of freshly prepared coffee and other beverages at affordable prices. Through this approach, Kopi Kenangan seeks to cater to the evolving preferences of coffee consumers in the region.

Lunit Inc. is a medical AI software company based in Seoul, South Korea, specializing in advanced algorithms for medical image analysis and general object detection. The company focuses on developing solutions that aid physicians in making objective diagnoses through machine learning technology. Lunit's expertise encompasses various medical imaging fields, including digital chest X-ray, digital mammography, digital pathology, and fundus photography. The company's products include Lunit INSIGHT CXR for chest X-rays, Lunit INSIGHT MMG for mammography, and Lunit SCOPE, which provides AI-powered biomarkers for immuno-oncology. Lunit aims to enhance clinical decision-making by leveraging data-driven imaging biomarker technology, ultimately improving the accuracy and efficiency of cancer care. The effectiveness of Lunit's deep learning technology has been validated through its recognition in major image recognition competitions, showcasing its capacity to process complex medical imaging data.

Acelyrin is a late-stage clinical biopharmaceutical company dedicated to advancing new treatment options for patients. The company specializes in identifying, acquiring, and accelerating the development and commercialization of promising drug candidates. By leveraging its expertise, Acelyrin aims to rapidly bring transformative medicines to market, ultimately improving patient outcomes and quality of life.

Caddi, Inc. is a technology company based in Tokyo, Japan, focused on providing innovative solutions for the manufacturing sector. The company operates an online ordering platform that facilitates the management of order placements for industrial products. This platform utilizes an automatic estimation system powered by a proprietary costing algorithm to connect custom-made processed products with processing plants, ensuring the optimal factory is identified for each order. Caddi's offerings include both goods and software, aimed at enhancing supply chain efficiency through procurement intelligence. By leveraging AI-driven data, Caddi helps businesses minimize procurement expenses, improve quality, cost, and delivery (QCD), and expand operational capacity.

Zentera Therapeutics is a biopharmaceutical company.

Amylyx Pharmaceuticals, Inc. is a biotechnology company focused on developing innovative therapies for neurodegenerative diseases, particularly Amyotrophic Lateral Sclerosis (ALS), Alzheimer’s disease, and Wolfram syndrome. Founded in 2013 and based in Cambridge, Massachusetts, the company is best known for its investigational therapy AMX0035, a fixed-dose co-formulation of sodium phenylbutyrate and Taurursodiol. This treatment aims to address the energy crisis within mitochondria and the accumulation of toxic, unfolded proteins in the endoplasmic reticulum, both of which contribute to the progression of neurodegenerative conditions. Through its research and development efforts, Amylyx seeks to provide effective solutions to mitigate the suffering caused by these debilitating diseases.

Wugen is a biotechnology company focused on developing innovative off-the-shelf cellular therapies for cancer treatment. The company specializes in natural killer (NK) cell and CAR-T immuno-oncology therapies, utilizing healthy donor cells that are manipulated to enhance their ability to target and eliminate cancer cells. Wugen's proprietary Moneta platform, along with its expertise in genomic engineering, allows for the creation of a new class of memory NK cell therapies aimed at addressing solid tumors, acute myeloid leukemia, and T-cell malignancies. Through its advancements, Wugen seeks to provide effective treatment options for patients facing life-threatening tumors.

Paidy Inc. is a Tokyo-based company established in 2008, specializing in a cardless real-time payment network that simplifies online transactions for consumers. Formerly known as Exchange Corporation K.K., the company rebranded in 2018 to reflect its focus on providing an efficient payment solution that does not require credit cards or pre-registration. Paidy's software platform allows users to make purchases online and pay for them through a consolidated monthly bill, leveraging proprietary technology to assess creditworthiness and guarantee payments to merchants. This approach caters particularly to Japanese consumers, many of whom prefer avoiding credit cards for online shopping. By facilitating cardless payments, Paidy helps eCommerce operators enhance their conversion rates, increase average order values, and boost repeat purchases.

Momo is a FinTech startup that provides a mobile electronic wallet and payment application for iOS and Android devices, primarily serving customers in Vietnam. The platform facilitates nationwide cash transfers, bill payments for over 100 types of services, mobile phone recharges, and personal loan settlements. Additionally, Momo enables users to purchase various services, including software licenses, online gaming cards, and tickets for airlines and movies. The company collaborates with 24 domestic banks and international payment networks, ensuring secure and efficient financial transactions for its users. Momo aims to simplify the payment experience, making it effortless and safe for individuals to manage their financial activities.

Provivi Inc. is a biotechnology company based in Santa Monica, California, focused on the development of biopesticides for agricultural, commercial, household, and public health pest management. Founded in 2013, the company leverages biocatalysis technology, originally developed at the California Institute of Technology, to create insect pheromones that protect food supplies without toxic residues. Provivi aims to provide effective and environmentally friendly crop protection solutions, fostering sustainable agricultural practices. Its innovative approach targets the synthesis of biopesticides through advanced processes, allowing for the efficient production of safe and affordable pest management products. The company distributes its offerings worldwide, seeking to transform pest control with its groundbreaking biological solutions.

LianBio is a biopharmaceutical company founded in 2019, headquartered in Shanghai, China, with an additional office in Princeton, New Jersey. The company is dedicated to the discovery and development of therapeutic drugs aimed at treating oncology and cardiorenal diseases, as well as addressing other unmet medical needs in Greater China and major Asian markets. LianBio focuses on in-licensing assets and collaborates with leading partners to enhance its pipeline, which includes clinically validated product candidates across various therapeutic areas such as cardiovascular, oncology, ophthalmology, inflammatory diseases, and respiratory indications. The company aims to accelerate the availability of innovative medicines to improve patient outcomes through a science-driven approach.

Zentera Therapeutics is a biopharmaceutical company.

Paidy Inc. is a Tokyo-based company established in 2008, specializing in a cardless real-time payment network that simplifies online transactions for consumers. Formerly known as Exchange Corporation K.K., the company rebranded in 2018 to reflect its focus on providing an efficient payment solution that does not require credit cards or pre-registration. Paidy's software platform allows users to make purchases online and pay for them through a consolidated monthly bill, leveraging proprietary technology to assess creditworthiness and guarantee payments to merchants. This approach caters particularly to Japanese consumers, many of whom prefer avoiding credit cards for online shopping. By facilitating cardless payments, Paidy helps eCommerce operators enhance their conversion rates, increase average order values, and boost repeat purchases.

Provivi Inc. is a biotechnology company based in Santa Monica, California, focused on the development of biopesticides for agricultural, commercial, household, and public health pest management. Founded in 2013, the company leverages biocatalysis technology, originally developed at the California Institute of Technology, to create insect pheromones that protect food supplies without toxic residues. Provivi aims to provide effective and environmentally friendly crop protection solutions, fostering sustainable agricultural practices. Its innovative approach targets the synthesis of biopesticides through advanced processes, allowing for the efficient production of safe and affordable pest management products. The company distributes its offerings worldwide, seeking to transform pest control with its groundbreaking biological solutions.

CarDekho provides enterprise mobility solutions, mobile application development, Web design and development, offshore staffing, and testing and quality assurance (QA) services. Its enterprise mobility solutions include enterprise mobility consulting, mobile business intelligence, business process mobilization, B2B mobile applications (app) development, enterprise iOS app development, enterprise Android app development, and enterprise app distribution; and mobile app development services include iPhone, iPad, Android, Blackberry, Windows8, Phonegap, and bootstrap. CarDekho’s Web design and development services include responsive design, PSD to HTML conversion, flash Website design, themes customization, content management system, E-commerce solution, CRM app development, open-source development, custom Web app development, regular Website maintenance, customized programming, online marketing, graphic design, Website hosting, employee management system, logo design, inventory management, and database design. Its offshore staffing services for designers, mobile apps developers,.NET developers, PHP developers, Java developers, Python developers, and ROR developers; and testing and QA services include automated, manual, usability, nonfunctional, specialized, mobile app, testing-as-a-service, integration, functional, system, localization, and acceptance testing. CarDekho develops entertainment, GPS tracking, weather, business and finance-related, multi-media, sports, social networking, education, and travel applications. It serves the automobile, E-learning, consultancy, finance, social networking, tours and travel, health and fitness, medical, job and career, news and magazine, utility/productivity, entertainment, lifestyle, and E-commerce industries; and IT and communication, and book and library industries.

Bicycle Therapeutics plc is a clinical-stage biopharmaceutical company based in Cambridge, United Kingdom, specializing in the development of a novel class of medicines known as Bicycles. These are synthetic short peptides designed to form two loops that stabilize their structure. The company's lead product candidate, BT1718, is a Bicycle Toxin Conjugate (BTC) currently undergoing Phase I/IIa clinical trials targeting tumors that express Membrane Type 1 matrix metalloprotease. Other oncology candidates include BT5528, also a BTC in Phase I/IIa trials targeting EphA2, and BT8009, which is in preclinical studies targeting Nectin-4. Additionally, Bicycle is advancing THR-149, a plasma kallikrein inhibitor that has completed Phase I trials for diabetic macular edema. The company collaborates with various biopharmaceutical organizations to address therapeutic areas such as anti-infective, cardiovascular, ophthalmology, and respiratory indications. Bicycle Therapeutics was incorporated in 2009 and aims to address significant unmet medical needs in oncology and beyond.

FreeCharge is an e-commerce platform based in Mumbai, Maharashtra, specializing in online recharges for prepaid mobile phones, postpaid services, DTH, and data cards in India. Founded in August 2010 by Kunal Shah, FreeCharge revolutionized the recharge process by offering shopping coupons from major retailers as an incentive, effectively making recharges cost-free for users. Initially, the platform partnered with brands like McDonald's and Barista, later expanding to include prominent retailers such as Café Coffee Day, Domino's Pizza, and Shoppers Stop. By November 2012, FreeCharge reported daily online recharge transactions worth INR 6 million, amounting to INR 2.19 billion annually. In addition to recharges, the platform also facilitates bill payments for services like electricity, gas, and telecommunication, allowing users to complete transactions quickly and efficiently across various channels. Recognized for its innovative approach, FreeCharge was named one of India's most promising technology startups in 2011.

CarDekho provides enterprise mobility solutions, mobile application development, Web design and development, offshore staffing, and testing and quality assurance (QA) services. Its enterprise mobility solutions include enterprise mobility consulting, mobile business intelligence, business process mobilization, B2B mobile applications (app) development, enterprise iOS app development, enterprise Android app development, and enterprise app distribution; and mobile app development services include iPhone, iPad, Android, Blackberry, Windows8, Phonegap, and bootstrap. CarDekho’s Web design and development services include responsive design, PSD to HTML conversion, flash Website design, themes customization, content management system, E-commerce solution, CRM app development, open-source development, custom Web app development, regular Website maintenance, customized programming, online marketing, graphic design, Website hosting, employee management system, logo design, inventory management, and database design. Its offshore staffing services for designers, mobile apps developers,.NET developers, PHP developers, Java developers, Python developers, and ROR developers; and testing and QA services include automated, manual, usability, nonfunctional, specialized, mobile app, testing-as-a-service, integration, functional, system, localization, and acceptance testing. CarDekho develops entertainment, GPS tracking, weather, business and finance-related, multi-media, sports, social networking, education, and travel applications. It serves the automobile, E-learning, consultancy, finance, social networking, tours and travel, health and fitness, medical, job and career, news and magazine, utility/productivity, entertainment, lifestyle, and E-commerce industries; and IT and communication, and book and library industries.

Girnar Software (SEZ) Private Limited, founded in 2007, is a mobile and web solutions development company that specializes in software development. With a team of over 900 skilled engineers and management professionals, the company focuses on delivering comprehensive services, including product development, manual and automation testing, mobile application development, and custom software solutions. GirnarSoft also operates automotive portals and marketplaces, providing businesses with the tools to achieve their IT objectives and enhance overall value. The company is a member of prominent organizations such as the National Association of Software and Services Companies and the Software Technology Parks of India, further solidifying its commitment to quality and innovation in the software industry.

Snapdeal is India's largest online marketplace, launched in February 2010, that connects buyers and sellers across a wide range of product categories including mobile phones, electronics, apparel, cosmetics, and home goods. The platform is designed to create a reliable and frictionless commerce ecosystem, offering convenient delivery options even to remote areas. Snapdeal is notable for its competitive pricing, featuring daily deals and discounts that make various products accessible to consumers. It has established itself as a market leader in the retail space and is recognized for its significant presence in categories such as watches, sunglasses, and jewelry. With over 1,000 employees, Snapdeal fosters a vibrant work environment and continues to play a critical role in India's e-commerce landscape.