U.S. Venture Partners

U.S. Venture Partners is a Menlo Park-based venture capital firm established in 1981 that concentrates on early-stage and growth investments in technology and healthcare. The firm backs business-to-business software, IT security, consumer internet, mobile, e-commerce, and IT-enabled healthcare services, as well as digital health, cloud technology, and life sciences including oncology. Its focus spans enterprise software, cybersecurity, healthcare IT, SaaS, manufacturing, and related sectors on the West Coast. The team comprises former entrepreneurs, technologists, executives, and industry experts who help portfolio companies scale and reach customers.

Dale Holladay

CFO

588 past transactions

HeartFlow

Convertible Note in 2025
HeartFlow specializes in precision heart care, offering a non-invasive solution for diagnosing coronary artery disease. Its proprietary HeartFlow FFRCT Analysis uses artificial intelligence to create a personalized 3D model of the heart, enabling clinicians to evaluate blood flow and determine optimal treatment. Commercially available in the United States, UK, Canada, Europe, and Japan.

MicroTransponder

Series F in 2025
MicroTransponder is a medical device company that develops and commercializes implantable neurostimulation platforms aimed at treating neurological conditions. The company focuses on vagus nerve stimulation to promote neuroplasticity and functional recovery, with products including the Serenity System for tinnitus and Vivistim, an FDA-approved therapy for ischemic stroke survivors with moderate to severe upper-limb impairment more than six months post-stroke. Founded in 2007 and headquartered in Austin, Texas, MicroTransponder's technology combines paired vagus nerve stimulation with wireless delivery of targeted electrical impulses to enhance recovery after neurological injury and disease.

Shoulder Innovations

Series E in 2025
Shoulder Innovations designs and manufactures medical devices for shoulder replacement surgery, focusing on inset glenoid fixation technology to provide a stable glenoid platform and reliable fixation. Its product portfolio includes InSet Total Shoulder Arthroplasty, InSet Reverse Shoulder Arthroplasty, ProVoyance Shoulder Planning Software, and InSet Tray System, along with associated instrumentation. The company distributes its products through partners in the United States and aims to reduce operative time and overall healthcare costs while improving post-surgical implant stability. Founded in 2009, the company is based in Holland, Michigan.

Nervonik

Series A in 2025
Nervonik is a medical device company developing an opioid-free peripheral nerve stimulation system and a neuro-modulation device with miniaturized sensing feedback for closed-loop therapy, aimed at treating chronic neuropathic pain. The company focuses on advancing clinical research and achieving regulatory milestones to bring its therapies to market.

Delfina

Series A in 2025
Delfina operates a data-driven prenatal care system designed to enhance maternal and infant safety during pregnancy. The company employs machine learning models to optimize interventional workflows and create personalized care plans based on patient risk factors, thereby facilitating early interventions and improving provider efficiency. This approach aims to deliver equitable and cost-effective pregnancy care within the healthcare industry.

Quantifind

Venture Round in 2025
Quantifind is a data science company that develops AI-powered platforms for marketing insight and financial crime risk management. Its Signum suite merges internal data with public information to reveal revenue drivers, explain what and who influences brand performance, and measure sponsorship impact on awareness and sales across automotive, consumer goods, entertainment, financial services, pharmaceutical, retail, and telecom sectors. The company also provides financial crime intelligence solutions for anti-money laundering and fraud detection, delivering real-time risk assessments, uncovering hidden threats, and reducing false positives by leveraging unstructured external data alongside internal records. Quantifind serves financial institutions and other organizations seeking faster, more precise risk detection, improved compliance, and scalable, data-driven decision support.

Stream Security

Series B in 2024
Lightlytics specializes in cloud deployment technologies that assist SRE and DevOps teams in managing infrastructure updates and developments. The company provides a continuously updated model of cloud environments by tracking behavior and configuration changes. Its technology enables teams to automatically predict, pre-empt, and prevent potential failures, downtime, and business disruptions by simulating all possible dependencies and assessing their impact on operations prior to deployment. This capability allows organizations to code and deploy configurations efficiently and securely, ensuring smooth operations from code to cloud.

Okami Medical

Venture Round in 2024
Okami Medical, Inc. is a medical device manufacturer based in Aliso Viejo, California, specializing in the occlusion of peripheral vessels to treat cardiovascular disease. The company's flagship product, the LOw-profile Braided Occluder (LOBO), is designed to provide interventional physicians with a single, versatile device for occluding various arterial targets without the need for multiple embolic devices. The LOBO system features a patented design and proprietary HDBRAID technology, which creates a highly occlusive pore structure that effectively reduces blood flow and accelerates vessel closure. Founded in 2011, Okami Medical aims to meet the evolving needs of patients and healthcare providers by offering innovative solutions that ensure rapid and reliable vessel occlusion, regardless of anatomical challenges.

ShiraTronics

Series B in 2024
ShiraTronics develops neuromodulation therapies to treat chronic migraine by delivering continuous stimulation to targeted nerves to relieve, interrupt, and prevent migraine episodes. Founded in 2018 and based in Ireland, the company maintains an additional location in Minneapolis, Minnesota, and pursues innovative neuromodulation technology to address unmet neurological needs and improve patient outcomes.

Route 92

Series F in 2024
Route 92 Medical, established in 2015 and headquartered in San Mateo, California, specializes in the development of innovative medical devices for stroke treatment. Their flagship product is a stealthy catheter designed for rapid and efficient removal of blood clots during acute ischemic stroke, aiming to improve patient outcomes and enhance recovery. Additionally, the company offers a rapid aspiration thrombectomy system and an intra-cerebral implant delivery system, further expanding their capabilities in stroke care.

Sepio

Series B in 2024
Sepio is a developer of an asset risk management platform focused on protecting organizations from hardware-based attacks. The company's innovative solution operates on asset existence rather than activity, utilizing physical layer asset DNA profiling to deliver actionable visibility and policy enforcement. This platform enables security teams to gain comprehensive insights into their hardware assets and monitor their behavior in real-time. With the ability to define granular device usage rules, Sepio allows administrators to continuously oversee and safeguard their infrastructure. The solution is asset agnostic, accommodating various environments including IT, OT, and IoT, and can report on existing assets and their associated risk factors within 24 hours. Ultimately, Sepio aims to enhance clients' cybersecurity posture by providing robust control over hardware assets and mitigating the risks posed by rogue devices.

Sparrow Pharmaceuticals

Venture Round in 2024
Sparrow Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing treatments for disorders of corticosteroid excess. Founded in 2013 and based in Portland, Oregon, the company seeks to spare patients from the adverse effects of steroids by leveraging insights into corticosteroid biology. Its lead product, SPI-62, is an oral small molecule designed to target the source of active intracellular corticosteroids in key tissues, with a pipeline aimed at hypercortisolism and related autoimmune and inflammatory conditions caused by endogenous cortisol excess or long-term corticosteroid therapy.

Carlsmed

Series C in 2024
Carlsmed specializes in medical technology for spine surgery, offering the aprevo™ system, an FDA-designated breakthrough technology for personalized lumbar fusion surgery. Headquartered in San Diego, California, Carlsmed was founded in 2018.

Cagent Vascular

Series C in 2024
Cagent Vascular, LLC is a medical device company that specializes in developing innovative angioplasty balloons utilizing proprietary serration technology. Incorporated in 2014 and based in Wayne, Pennsylvania, the company has created the Serranator, a unique angioplasty device featuring serrated metal strips embedded in a semi-compliant balloon. This device is designed to treat atherosclerosis by effectively addressing blocked arteries, particularly in patients with peripheral artery disease and chronic limb-threatening ischemia. Cagent Vascular's technology aims to enhance the effectiveness of vessel dilatation procedures in cardiovascular interventions, providing healthcare providers with advanced tools to improve patient outcomes.

IONIX

Series A in 2024
IONIX is a security solutions provider specializing in attack surface management through its innovative platform, which leverages Connective Intelligence to identify and mitigate exploitable risks across both digital and internet-facing assets. The company's technology employs machine learning to discover and monitor organizational assets, analyze their connections, and assess risks with a contextual approach. By utilizing inside-out and reverse detection techniques, IONIX helps organizations uncover new vulnerabilities and respond to risky changes effectively. Its comprehensive suite of tools facilitates the prioritization of critical threats and supports end-to-end remediation workflows. Esteemed global companies, such as Infosys and Warner Music Group, rely on IONIX to enhance their security posture and proactively manage their complex attack surfaces in an ever-evolving threat landscape.

Zero Networks

Series B in 2023
Zero Networks Inc. is a network security software developer founded in 2019 and headquartered in Tel Aviv, Israel. The company specializes in automating the definition, enforcement, and adaptation of network access policies for users and machines within an organization. Its cloud-based technology customizes access controls by learning how users and devices communicate, thereby enhancing security without the need for agents or complex policy configurations. Additionally, Zero Networks incorporates a two-factor authentication mechanism that allows legitimate but unusual connections through a secure wall on mobile devices. This approach ensures robust protection against potential breaches while maintaining operational continuity, making it an effective solution for organizations seeking to strengthen their network security posture.

Stensul

Series C in 2023
Stensul streamlines enterprise marketing by offering a centralized email generation platform. It enables marketers to create mobile-responsive emails that adhere to brand guidelines, bypassing the need for designer, developer, and QA involvement. Emails can be instantly sent through popular ESPs or Marketing Clouds.

Route 92

Series F in 2023
Route 92 Medical, established in 2015 and headquartered in San Mateo, California, specializes in the development of innovative medical devices for stroke treatment. Their flagship product is a stealthy catheter designed for rapid and efficient removal of blood clots during acute ischemic stroke, aiming to improve patient outcomes and enhance recovery. Additionally, the company offers a rapid aspiration thrombectomy system and an intra-cerebral implant delivery system, further expanding their capabilities in stroke care.

Darwinium

Series A in 2023
Darwinium is a technology company that specializes in a decision technology platform aimed at enhancing security, combating fraud, and improving customer experience. The platform employs integrated machine learning, orchestration, and analytics to protect mobile applications, websites, and APIs from sophisticated automated attacks. By focusing on customer privacy and minimizing risk exposure, Darwinium implements techniques such as anonymization, masking, and secure computing. This comprehensive approach enables clients to increase revenues, reduce fraud losses, and effectively block bot activity, thereby creating a safer digital environment for users.

Luminopia

Series A in 2023
Luminopia is a company focused on developing innovative treatments for significant neuro-visual disorders, particularly amblyopia, commonly known as lazy eye, which is a leading cause of vision loss in children. By creating engaging digital therapeutics, Luminopia aims to provide effective solutions that are rigorously evaluated for FDA approval. Their flagship product, Luminopia One, leverages binocular vision techniques to address amblyopia, enabling healthcare professionals to offer new treatment options for affected patients. Partnering with Boston Children’s Hospital, Luminopia is at the forefront of pioneering advanced therapeutic approaches that enhance patient care in the field of pediatric vision health.

TrustLab

Series A in 2023
TrustLab is an AI software company used to protect against misinformation, hate speech, identity fraud, and other harmful content.

Percepto

Series C in 2023
Percepto is a developer of autonomous drone technology for inspection and surveillance. The company is at the forefront of redefining how industrial sites and critical infrastructure are holistically inspected and monitored, harnessing remote robotics to autonomously collect, aggregate, and analyze visual data. Leveraging its experience with Percepto Sparrow, the first deployed drone-in-a-box solution on the market, Percepto introduced Percepto AIM (Autonomous Inspection and Monitoring), the first end-to-end autonomous inspection and monitoring platform. Percepto AIM empowers the remote operation center of the future to assess risk, minimize downtime, drive efficiency, increase safety, and reduce operational costs.

Surgical Safety Technologies

Series A in 2023
Surgical Safety Technologies is a company focused on enhancing the safety and efficiency of healthcare through its AI-driven medical technology platform. The company provides hospitals with data-driven solutions that empower surgeons by offering an objective assessment of both technical and non-technical skills based on academically validated frameworks. Its platform generates descriptive, predictive, and prescriptive insights that support informed clinical and operational decision-making, ultimately aiming to improve surgical quality and patient safety.

HeartFlow

Series F in 2023
HeartFlow specializes in precision heart care, offering a non-invasive solution for diagnosing coronary artery disease. Its proprietary HeartFlow FFRCT Analysis uses artificial intelligence to create a personalized 3D model of the heart, enabling clinicians to evaluate blood flow and determine optimal treatment. Commercially available in the United States, UK, Canada, Europe, and Japan.

Shoulder Innovations

Series D in 2023
Shoulder Innovations designs and manufactures medical devices for shoulder replacement surgery, focusing on inset glenoid fixation technology to provide a stable glenoid platform and reliable fixation. Its product portfolio includes InSet Total Shoulder Arthroplasty, InSet Reverse Shoulder Arthroplasty, ProVoyance Shoulder Planning Software, and InSet Tray System, along with associated instrumentation. The company distributes its products through partners in the United States and aims to reduce operative time and overall healthcare costs while improving post-surgical implant stability. Founded in 2009, the company is based in Holland, Michigan.

Quantifind

Venture Round in 2023
Quantifind is a data science company that develops AI-powered platforms for marketing insight and financial crime risk management. Its Signum suite merges internal data with public information to reveal revenue drivers, explain what and who influences brand performance, and measure sponsorship impact on awareness and sales across automotive, consumer goods, entertainment, financial services, pharmaceutical, retail, and telecom sectors. The company also provides financial crime intelligence solutions for anti-money laundering and fraud detection, delivering real-time risk assessments, uncovering hidden threats, and reducing false positives by leveraging unstructured external data alongside internal records. Quantifind serves financial institutions and other organizations seeking faster, more precise risk detection, improved compliance, and scalable, data-driven decision support.

HealthJoy

Series D in 2022
HealthJoy is a healthcare technology company that provides a benefits experience and care navigation platform designed to simplify healthcare for employees and reduce costs for employers. Its AI-driven virtual assistants help users find cost-effective care options, access doctors and insurance experts, and compare care choices. The platform integrates a company's existing benefits to deliver a personalized digital benefits wallet and supports claims, health savings accounts, and prescription management. It offers on-demand online medical consultations, live healthcare concierges, and Rx savings, enabling employees to become informed healthcare shoppers. By streamlining benefits utilization and guidance, HealthJoy aims to improve employee satisfaction and contain benefit-related expenditures. The company is based in Chicago, Illinois.

Sepio

Series B in 2022
Sepio is a developer of an asset risk management platform focused on protecting organizations from hardware-based attacks. The company's innovative solution operates on asset existence rather than activity, utilizing physical layer asset DNA profiling to deliver actionable visibility and policy enforcement. This platform enables security teams to gain comprehensive insights into their hardware assets and monitor their behavior in real-time. With the ability to define granular device usage rules, Sepio allows administrators to continuously oversee and safeguard their infrastructure. The solution is asset agnostic, accommodating various environments including IT, OT, and IoT, and can report on existing assets and their associated risk factors within 24 hours. Ultimately, Sepio aims to enhance clients' cybersecurity posture by providing robust control over hardware assets and mitigating the risks posed by rogue devices.

SecuriThings

Series B in 2022
SecuriThings, Inc. specializes in providing comprehensive security solutions for Internet of Things (IoT) devices, leveraging big data and machine learning to detect cyber threats in real time. Founded in 2015 and headquartered in Tel Aviv, Israel, with an additional office in New York, the company offers a robust platform that enhances security and operational efficiency for organizations managing large fleets of IoT devices. Their Horizon platform integrates cloud-connected devices, delivering automation, analytics, and actionable alerts to ensure system availability, compliance, and cyber protection. Trusted by Fortune 100 companies, SecuriThings' solutions have been deployed in various sectors, including major airports, universities, and hospitals. Through partnerships with system integrators and device manufacturers, the company provides extensive insights and reliability in managing IoT security.

Oliver Space

Series B in 2022
Founded in San Francisco in 2018 by Chan Park, Oliver Space is a home furnishing company that simplifies and affords living space customization. It offers a wide range of products from sofas to plants on a flexible rent or buy basis, with a unique try-before-you-buy option at 0% interest.

TaskHuman

Series B in 2022
TaskHuman is a real-time digital coaching platform that delivers 1-on-1 video coaching through a global network of wellness professionals. The platform connects users with athletic trainers, life coaches, nutritionists, holistic wellness practitioners, yoga instructors, and strength and conditioning coaches for fitness and well-being guidance across more than 1,000 topics. Founded in 2017 and based in Palo Alto, TaskHuman enables on-demand, personalized coaching across physical fitness, mental well-being, spiritual, emotional, financial, career, and leadership areas. It serves individual users and organizations seeking to improve health, performance, and engagement by providing instant access to coaching via video calls.

MicroTransponder

Series E in 2022
MicroTransponder is a medical device company that develops and commercializes implantable neurostimulation platforms aimed at treating neurological conditions. The company focuses on vagus nerve stimulation to promote neuroplasticity and functional recovery, with products including the Serenity System for tinnitus and Vivistim, an FDA-approved therapy for ischemic stroke survivors with moderate to severe upper-limb impairment more than six months post-stroke. Founded in 2007 and headquartered in Austin, Texas, MicroTransponder's technology combines paired vagus nerve stimulation with wireless delivery of targeted electrical impulses to enhance recovery after neurological injury and disease.

nfinite

Series B in 2022
Nfinite is a company that specializes in developing a sophisticated CGI platform that employs artificial intelligence and 3D technology to enhance product visualization for brands and retailers. Founded in 2017 and operating in both the United States and France, Nfinite provides an innovative solution for product merchandising by enabling the creation of high-quality visual content through virtual shooting. This technology allows retailers to replace traditional photographic images with dynamic and customizable visuals, thus improving online and catalog displays. Additionally, Nfinite offers comprehensive AI training and fine-tuning services, utilizing synthetic data to optimize AI models for specific industry applications. This approach ensures enhanced performance and efficiency, positioning Nfinite as a key partner for businesses seeking to leverage AI-driven visual experiences.

Carlsmed

Series B in 2022
Carlsmed specializes in medical technology for spine surgery, offering the aprevo™ system, an FDA-designated breakthrough technology for personalized lumbar fusion surgery. Headquartered in San Diego, California, Carlsmed was founded in 2018.

IONIX

Series A in 2022
IONIX is a security solutions provider specializing in attack surface management through its innovative platform, which leverages Connective Intelligence to identify and mitigate exploitable risks across both digital and internet-facing assets. The company's technology employs machine learning to discover and monitor organizational assets, analyze their connections, and assess risks with a contextual approach. By utilizing inside-out and reverse detection techniques, IONIX helps organizations uncover new vulnerabilities and respond to risky changes effectively. Its comprehensive suite of tools facilitates the prioritization of critical threats and supports end-to-end remediation workflows. Esteemed global companies, such as Infosys and Warner Music Group, rely on IONIX to enhance their security posture and proactively manage their complex attack surfaces in an ever-evolving threat landscape.

Kryptowire

Venture Round in 2022
Kryptowire was jumpstarted by the Defense Advanced Research Projects Agency (DARPA) and the Department of Homeland Security (DHS S&T), and has been vetted by the US military, law enforcement, and intelligence agencies. Kryptowire provides mobile application security analysis tools, anti‐piracy technologies, mobile app marketplace security analytics, and Enterprise Mobility Management (EMM) solutions. Kryptowire was founded in 2011, is based in Fairfax, Virginia, and has a customer base ranging from government agencies to national cable TV companies.

nfinite

Series A in 2022
Nfinite is a company that specializes in developing a sophisticated CGI platform that employs artificial intelligence and 3D technology to enhance product visualization for brands and retailers. Founded in 2017 and operating in both the United States and France, Nfinite provides an innovative solution for product merchandising by enabling the creation of high-quality visual content through virtual shooting. This technology allows retailers to replace traditional photographic images with dynamic and customizable visuals, thus improving online and catalog displays. Additionally, Nfinite offers comprehensive AI training and fine-tuning services, utilizing synthetic data to optimize AI models for specific industry applications. This approach ensures enhanced performance and efficiency, positioning Nfinite as a key partner for businesses seeking to leverage AI-driven visual experiences.

Hunters

Series C in 2022
Hunters is a cybersecurity company that specializes in developing an artificial intelligence-based platform for detecting and responding to cyber threats. Founded in 2018 and headquartered in Tel Aviv, Israel, the company offers its solution, Hunters.AI, which autonomously identifies cyberattacks that may evade traditional security measures across various IT environments, including cloud and network systems. Hunters.AI integrates diverse security telemetry and intelligence, enriching threat signals with detailed tactics, techniques, and procedures to enhance detection capabilities. By utilizing machine learning and cloud-based analytics, the platform correlates threat patterns and generates high-fidelity attack narratives, enabling cybersecurity teams to respond swiftly and effectively to potential breaches.

Qnovo

Series C in 2022
Founded in 2010, Qnovo specializes in intelligent battery management software and predictive analytics for lithium-ion batteries. The company enhances the performance of electric vehicles, energy storage systems, and consumer devices, improving their health, safety, and lifespan. Headquartered in Milpitas, California, Qnovo works with leading automotive OEMs and has over 50 patents in the space.

Route 92

Series E in 2021
Route 92 Medical, established in 2015 and headquartered in San Mateo, California, specializes in the development of innovative medical devices for stroke treatment. Their flagship product is a stealthy catheter designed for rapid and efficient removal of blood clots during acute ischemic stroke, aiming to improve patient outcomes and enhance recovery. Additionally, the company offers a rapid aspiration thrombectomy system and an intra-cerebral implant delivery system, further expanding their capabilities in stroke care.

TaskHuman

Series A in 2021
TaskHuman is a real-time digital coaching platform that delivers 1-on-1 video coaching through a global network of wellness professionals. The platform connects users with athletic trainers, life coaches, nutritionists, holistic wellness practitioners, yoga instructors, and strength and conditioning coaches for fitness and well-being guidance across more than 1,000 topics. Founded in 2017 and based in Palo Alto, TaskHuman enables on-demand, personalized coaching across physical fitness, mental well-being, spiritual, emotional, financial, career, and leadership areas. It serves individual users and organizations seeking to improve health, performance, and engagement by providing instant access to coaching via video calls.

Luma Health

Series C in 2021
Founded in 2015, Luma Health develops a patient engagement platform that connects healthcare providers with patients via smart scheduling, appointment reminders, mobile intake, and care pathways. Its platform integrates with EHR systems for insights and analytics.

Effector Therapeutics

Post in 2021
eFFECTOR Therapeutics, Inc. is a clinical-stage biotechnology company based in San Diego, California, that specializes in the development of selective translation regulators for the treatment of cancer and other serious diseases. Founded in 2012, the company is pioneering a new class of oncology drugs known as selective translation regulator inhibitors (STRIs). These drug candidates specifically target the eIF4F complex and its associated kinase, MNK 1/2, which play critical roles in protein synthesis and are linked to prominent cancer signaling pathways such as PI3K-AKT and RAS-MEK. eFFECTOR's products aim to inhibit pathways that drive tumor growth, survival, and immune evasion by regulating the expression of oncoproteins and immunosuppressive proteins. The lead candidate, tomivosertib, is currently being evaluated in a Phase 2b trial for non-small cell lung cancer in combination with pembrolizumab. Additionally, zotatifin, an inhibitor of eIF4A, is undergoing dose-escalation in a Phase 1/2 trial, with further expansion cohorts anticipated. The company also collaborates with Pfizer to advance inhibitors targeting eIF4E.

Hunters

Series B in 2021
Hunters is a cybersecurity company that specializes in developing an artificial intelligence-based platform for detecting and responding to cyber threats. Founded in 2018 and headquartered in Tel Aviv, Israel, the company offers its solution, Hunters.AI, which autonomously identifies cyberattacks that may evade traditional security measures across various IT environments, including cloud and network systems. Hunters.AI integrates diverse security telemetry and intelligence, enriching threat signals with detailed tactics, techniques, and procedures to enhance detection capabilities. By utilizing machine learning and cloud-based analytics, the platform correlates threat patterns and generates high-fidelity attack narratives, enabling cybersecurity teams to respond swiftly and effectively to potential breaches.

Carrot Fertility

Series C in 2021
Carrot Fertility, Inc. offers comprehensive fertility benefits services for employers, supporting employees throughout their fertility healthcare journey on a global scale. Founded in 2015 and headquartered in San Francisco, California, the company provides a range of services including egg freezing, in vitro fertilization, adoption, donor and gestational carrier services. It also features Carrot Rx, a premium pharmacy experience for fertility medications, and Carrot Pregnancy, which offers virtual access to experts and on-demand doctor-approved content. Additionally, Carrot Card is a flexible debit card that employees can use to pay for fertility care. Carrot Fertility aims to help companies customize their fertility benefits, ensuring that employees receive the necessary financial, medical, and emotional support as they pursue parenthood. The company has expanded its presence with additional offices in major cities including Chicago, New York, Dublin, Geneva, Tokyo, and Seoul.

Human Interest

Series D in 2021
Human Interest is a retirement savings provider focused on small and medium-sized businesses, offering a 401(k) platform that simplifies administration and compliance through end-to-end technology. The platform automatically creates employee accounts, syncs payroll deductions, and provides personalized investment guidance, enabling SMBs to offer affordable, easy-to-manage retirement plans; the company has served thousands of businesses across the United States and was founded in 2015 in San Francisco by Paul Sawaya and Roger Lee.

Ribon Therapeutics

Series C in 2021
Ribon Therapeutics, Inc. is a biotechnology company founded in 2015 and headquartered in Lexington, Massachusetts. The company focuses on developing novel therapeutics that target monoPARP proteins, which are critical regulators of cancer cell survival mechanisms. By leveraging insights from its scientific founders, Ribon is establishing a proprietary drug discovery platform aimed at investigating the molecular actions and biological functions of a specific subset of the PARP protein family. This platform enables Ribon to create a pipeline of innovative small molecule inhibitors designed to disrupt the fundamental survival capabilities of cancer cells under stress. In addition to cancer treatment, the company's research may have implications for addressing other diseases. Ribon is supported by notable life science investors, which enhances its capacity to advance its therapeutic developments.

Standard Bariatrics

Series B in 2021
Standard Bariatrics is a medical device company based in Cincinnati, Ohio, specializing in the development of surgical instruments for weight-loss surgeries, particularly laparoscopic sleeve gastrectomy. Founded in 2014, the company has created a series of disposable surgical tools designed to work alongside general-use endoscopic staplers. These innovative tools help surgeons standardize their techniques, reduce variability, and minimize waste during procedures. By decreasing the number of cartridges needed for each surgery, Standard Bariatrics enables healthcare providers to lower costs while ensuring consistent surgical outcomes.

Oliver Space

Series A in 2021
Founded in San Francisco in 2018 by Chan Park, Oliver Space is a home furnishing company that simplifies and affords living space customization. It offers a wide range of products from sofas to plants on a flexible rent or buy basis, with a unique try-before-you-buy option at 0% interest.

Informed

Series A in 2021
Informed, Inc., established in 2016 and headquartered in San Francisco, California, operates a platform that connects buyers and sellers of pre-owned cars while also providing solutions for banks to enhance their digital transformation. The company offers turn-key robotic process automation that performs essential verification tasks, including income, identity, residence, and insurance verification. These services help banks minimize manual costs associated with document reviews, reduce the risk of fraud, mitigate bias, and decrease errors during loan origination and account openings. Additionally, Informed's consumer auto financing platform utilizes a digital assistant and machine learning with optical character recognition to streamline the collection and analysis of loan documents, thereby facilitating automated loan origination for auto lenders.

Sparrow Pharmaceuticals

Series A in 2021
Sparrow Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing treatments for disorders of corticosteroid excess. Founded in 2013 and based in Portland, Oregon, the company seeks to spare patients from the adverse effects of steroids by leveraging insights into corticosteroid biology. Its lead product, SPI-62, is an oral small molecule designed to target the source of active intracellular corticosteroids in key tissues, with a pipeline aimed at hypercortisolism and related autoimmune and inflammatory conditions caused by endogenous cortisol excess or long-term corticosteroid therapy.

AirEye

Series A in 2021
AirEye is a cybersecurity company that specializes in protecting organizations from airborne attacks targeting their network. Its flagship product, AirEye Dome, is a software-as-a-service platform that provides comprehensive visibility and control over all wireless communications, including Wi-Fi, cellular, 5G, and Bluetooth. By monitoring these channels in real-time, AirEye Dome can detect unauthorized access, block attacks, and prevent data leaks, all while seamlessly integrating with existing network security infrastructure. This platform addresses vulnerabilities posed by employee hotspots, shadow networks, and dual-connected devices, using AI-driven, agent-less technology to safeguard IT and operational technology assets. AirEye serves a diverse array of industries, such as finance, healthcare, manufacturing, retail, and aerospace, ensuring robust protection against potential threats in their corporate airspace.

Territory Foods

Series B in 2021
Founded in 2011, Territory Foods is a chef-prepared meal delivery service based in Arlington, VA. It offers personalized, nutritionist-approved menus featuring fresh, healthy meals tailored to various dietary preferences and regional tastes. Its rotating menus are responsibly sourced, free of refined sugars, gluten, and dairy, and can be customized to meet specific dietary templates like Vegan, Vegetarian, Whole30, and Keto.

Dapper Labs

Venture Round in 2021
Founded in 2018, Dapper Labs develops blockchain-based platforms that bring non-fungible tokens (NFTs) and innovative digital experiences to fans worldwide. Its flagship product, NBA Top Shot, engages consumers with their favorite brands by creating communities centered around ownership and creativity.

Dapper Labs

Series C in 2021
Founded in 2018, Dapper Labs develops blockchain-based platforms that bring non-fungible tokens (NFTs) and innovative digital experiences to fans worldwide. Its flagship product, NBA Top Shot, engages consumers with their favorite brands by creating communities centered around ownership and creativity.

Act-On Software

Venture Round in 2021
Act-On Software, Inc. is a developer of a cloud-based marketing automation platform tailored for small and mid-sized businesses. The platform enables marketers to create and manage various marketing campaigns, including email marketing, website lead generation, social media marketing, and account-based marketing. Act-On's solutions help organizations attract prospects, convert leads, and measure campaign effectiveness while enhancing customer engagement and brand awareness. Additionally, the company offers professional consulting, support, and training services to optimize the use of its platform. Act-On serves diverse industries such as banking, insurance, manufacturing, technology, and agencies. Founded in 2006 and headquartered in Portland, Oregon, Act-On also has locations in Scottsdale, Arizona, and Reading, United Kingdom.

Neuros Medical

Series B in 2021
Neuros Medical, Inc. is a neuromodulation company dedicated to developing innovative therapies to address unmet medical needs for patients globally. Founded in 2008 and headquartered in Willoughby Hills, Ohio, the company specializes in its proprietary platform technology known as Electrical Nerve Block. This technology is designed to eliminate chronic pain across various conditions, including neuroma/residual limb pain, chronic post-surgical pain, and chronic migraine. The Neuros Altius System, one of its key products, includes an implantable generator with an integrated rechargeable battery, a cuff electrode, and external devices, further demonstrating the company's commitment to advancing pain management solutions.

Carlsmed

Series A in 2020
Carlsmed specializes in medical technology for spine surgery, offering the aprevo™ system, an FDA-designated breakthrough technology for personalized lumbar fusion surgery. Headquartered in San Diego, California, Carlsmed was founded in 2018.

Edgewise Therapeutics

Series C in 2020
Edgewise Therapeutics is a clinical-stage biopharmaceutical company focused on developing innovative treatments for severe, rare muscle disorders with significant unmet medical need. It employs a holistic drug discovery approach targeting the muscle as an organ, utilizing its proprietary platform to identify precision medicines regulating key proteins in muscle tissue.

Percepto

Series B in 2020
Percepto is a developer of autonomous drone technology for inspection and surveillance. The company is at the forefront of redefining how industrial sites and critical infrastructure are holistically inspected and monitored, harnessing remote robotics to autonomously collect, aggregate, and analyze visual data. Leveraging its experience with Percepto Sparrow, the first deployed drone-in-a-box solution on the market, Percepto introduced Percepto AIM (Autonomous Inspection and Monitoring), the first end-to-end autonomous inspection and monitoring platform. Percepto AIM empowers the remote operation center of the future to assess risk, minimize downtime, drive efficiency, increase safety, and reduce operational costs.

Stensul

Series B in 2020
Stensul streamlines enterprise marketing by offering a centralized email generation platform. It enables marketers to create mobile-responsive emails that adhere to brand guidelines, bypassing the need for designer, developer, and QA involvement. Emails can be instantly sent through popular ESPs or Marketing Clouds.

Shoulder Innovations

Venture Round in 2020
Shoulder Innovations designs and manufactures medical devices for shoulder replacement surgery, focusing on inset glenoid fixation technology to provide a stable glenoid platform and reliable fixation. Its product portfolio includes InSet Total Shoulder Arthroplasty, InSet Reverse Shoulder Arthroplasty, ProVoyance Shoulder Planning Software, and InSet Tray System, along with associated instrumentation. The company distributes its products through partners in the United States and aims to reduce operative time and overall healthcare costs while improving post-surgical implant stability. Founded in 2009, the company is based in Holland, Michigan.

Silverback Therapeutics

Series C in 2020
Silverback Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Seattle, Washington, specializing in the development of tissue-targeted therapeutics aimed at treating cancer, chronic viral infections, and other serious diseases. The company’s lead product candidate, SBT6050, is currently in a Phase I/Ib clinical trial and is designed as a TLR8 agonist linker-payload conjugated to a HER2-directed monoclonal antibody, targeting tumors such as breast and non-small cell lung cancers. Silverback is also advancing SBT6290, a preclinical candidate targeting Nectin4 in various cancers, and SBT8230, which aims to treat chronic hepatitis B virus infection. The company employs its proprietary ImmunoTAC technology platform to create therapies that can be systemically administered while acting specifically at disease sites, thereby potentially modulating fundamental disease pathways previously considered inaccessible. Founded in 2016, Silverback Therapeutics is committed to innovative approaches in biopharmaceutical development.

Medigate by Claroty

Series B in 2020
Medigate by Claroty is a developer of a medical device security platform that safeguards healthcare provider networks from cyber threats. Founded in 2017, the company is headquartered in New York City and focuses on protecting all connected medical devices within these networks. Its platform utilizes deep packet inspection to decode proprietary healthcare IoT protocols, providing visibility and security for IoT and medical devices. By offering threat detection and attack prevention services, Medigate enhances the safety and privacy of hospital environments, allowing for the secure deployment of both existing and new medical devices.

Optimize Health

Series A in 2020
Optimize Health provides a digital platform for Remote Patient Monitoring (RPM), enabling healthcare providers to comply with new Medicare CPT codes while offering an intuitive user experience for patients and providers. Its system is designed to be profitable for physicians from the first month.

Carrot Fertility

Series B in 2020
Carrot Fertility, Inc. offers comprehensive fertility benefits services for employers, supporting employees throughout their fertility healthcare journey on a global scale. Founded in 2015 and headquartered in San Francisco, California, the company provides a range of services including egg freezing, in vitro fertilization, adoption, donor and gestational carrier services. It also features Carrot Rx, a premium pharmacy experience for fertility medications, and Carrot Pregnancy, which offers virtual access to experts and on-demand doctor-approved content. Additionally, Carrot Card is a flexible debit card that employees can use to pay for fertility care. Carrot Fertility aims to help companies customize their fertility benefits, ensuring that employees receive the necessary financial, medical, and emotional support as they pursue parenthood. The company has expanded its presence with additional offices in major cities including Chicago, New York, Dublin, Geneva, Tokyo, and Seoul.

Hunters

Series A in 2020
Hunters is a cybersecurity company that specializes in developing an artificial intelligence-based platform for detecting and responding to cyber threats. Founded in 2018 and headquartered in Tel Aviv, Israel, the company offers its solution, Hunters.AI, which autonomously identifies cyberattacks that may evade traditional security measures across various IT environments, including cloud and network systems. Hunters.AI integrates diverse security telemetry and intelligence, enriching threat signals with detailed tactics, techniques, and procedures to enhance detection capabilities. By utilizing machine learning and cloud-based analytics, the platform correlates threat patterns and generates high-fidelity attack narratives, enabling cybersecurity teams to respond swiftly and effectively to potential breaches.

Okami Medical

Series D in 2020
Okami Medical, Inc. is a medical device manufacturer based in Aliso Viejo, California, specializing in the occlusion of peripheral vessels to treat cardiovascular disease. The company's flagship product, the LOw-profile Braided Occluder (LOBO), is designed to provide interventional physicians with a single, versatile device for occluding various arterial targets without the need for multiple embolic devices. The LOBO system features a patented design and proprietary HDBRAID technology, which creates a highly occlusive pore structure that effectively reduces blood flow and accelerates vessel closure. Founded in 2011, Okami Medical aims to meet the evolving needs of patients and healthcare providers by offering innovative solutions that ensure rapid and reliable vessel occlusion, regardless of anatomical challenges.

Zerto

Series F in 2020
Zerto is a company that specializes in providing enterprise-class disaster recovery and business continuity software solutions. Founded in 2009 and headquartered in Boston, Massachusetts with additional offices globally, Zerto focuses on keeping IT infrastructure running continuously for both enterprises and cloud environments. Its flagship product, Zerto Virtual Replication, enables the protection, recovery, and migration of applications across various cloud and virtualized data centers. The company's BC/DR Platform offers disaster recovery as a service for public, private, and hybrid clouds, catering to industries such as healthcare, legal, and financial services.

Cato Networks

Series D in 2020
Cato Networks provides a cloud-based secure global SD-WAN and security platform that connects enterprise locations, remote users, and cloud data. The Cato Cloud integrates networking and security services, including WAN optimization, firewall, secure web gateway, threat protection, and UC optimization, delivered through a single management application. It eliminates branch appliances, reduces MPLS costs, and provides secure Internet access everywhere, enabling seamless integration of mobile users and cloud data centers into the WAN and simplifying site deployment and overall network security for distributed, mobile, and cloud-enabled enterprises.

Forager

Series A in 2020
Forager Logistics LLC, established in 2018 and based in Chicago, Illinois, specializes in freight brokerage and logistics services for the automotive and aerospace industries. The company offers a range of truckload services, including standard, expedited, and cross-border transportation, catering to supply chain networks with seamless and modern solutions. Forager's innovative web-based transportation management platform further enhances its service, targeting the complexities of cross-border shipping, particularly to and from Mexico and Canada.

Arkose Labs

Series B in 2020
Arkose Labs develops an online fraud and abuse prevention platform that protects businesses in sectors such as online marketplaces, travel, banking, social media, ticketing, and online gaming. The platform defends consumer actions against account takeover, fake account abuse, scraping, spam, and gift‑card fraud. Founded in 2015, the company is headquartered in San Mateo, California, with offices in London, Costa Rica, and Brisbane. It is recognized as a leader in bot detection and mitigation, offering a $1 million warranty for credential‑stuffing and SMS toll fraud. Arkose Labs’ AI‑powered system combines global telemetry, dynamic threat response, and a bilateral feedback loop to validate suspicious traffic and train enforcement, reducing friction for legitimate users while authenticating identities across all customer touchpoints.

Silverback Therapeutics

Series B in 2020
Silverback Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Seattle, Washington, specializing in the development of tissue-targeted therapeutics aimed at treating cancer, chronic viral infections, and other serious diseases. The company’s lead product candidate, SBT6050, is currently in a Phase I/Ib clinical trial and is designed as a TLR8 agonist linker-payload conjugated to a HER2-directed monoclonal antibody, targeting tumors such as breast and non-small cell lung cancers. Silverback is also advancing SBT6290, a preclinical candidate targeting Nectin4 in various cancers, and SBT8230, which aims to treat chronic hepatitis B virus infection. The company employs its proprietary ImmunoTAC technology platform to create therapies that can be systemically administered while acting specifically at disease sites, thereby potentially modulating fundamental disease pathways previously considered inaccessible. Founded in 2016, Silverback Therapeutics is committed to innovative approaches in biopharmaceutical development.

HealthJoy

Series C in 2020
HealthJoy is a healthcare technology company that provides a benefits experience and care navigation platform designed to simplify healthcare for employees and reduce costs for employers. Its AI-driven virtual assistants help users find cost-effective care options, access doctors and insurance experts, and compare care choices. The platform integrates a company's existing benefits to deliver a personalized digital benefits wallet and supports claims, health savings accounts, and prescription management. It offers on-demand online medical consultations, live healthcare concierges, and Rx savings, enabling employees to become informed healthcare shoppers. By streamlining benefits utilization and guidance, HealthJoy aims to improve employee satisfaction and contain benefit-related expenditures. The company is based in Chicago, Illinois.

Epsagon

Series A in 2020
Epsagon Ltd. is a technology company based in Tel Aviv, Israel, founded in 2017. It specializes in developing solutions for monitoring serverless architecture systems, providing a Software as a Service (SaaS) platform that enhances visibility and troubleshooting capabilities for Dev and Ops teams. Epsagon's platform enables organizations to achieve end-to-end observability in microservice environments by offering automated data correlation, payload analysis, and performance tracking. This comprehensive monitoring allows enterprises to predict and address potential performance issues before they impact operations, thereby reducing application downtime and enhancing engineering efficiency. With a focus on ease of use, Epsagon's lightweight agent SDK facilitates automated instrumentation and tracing without the need for manual coding or maintenance. The company aims to optimize operational costs through scalable pricing and unlimited free monitoring, catering to organizations of all sizes.

ShiraTronics

Series A in 2019
ShiraTronics develops neuromodulation therapies to treat chronic migraine by delivering continuous stimulation to targeted nerves to relieve, interrupt, and prevent migraine episodes. Founded in 2018 and based in Ireland, the company maintains an additional location in Minneapolis, Minnesota, and pursues innovative neuromodulation technology to address unmet neurological needs and improve patient outcomes.

Kenna Security

Series D in 2019
Kenna Security, founded in 2009 and headquartered in San Francisco with an additional office in Chicago, is a technology company specializing in vulnerability management and risk intelligence solutions. It offers Kenna, a SaaS platform that helps organizations accurately measure and prioritize cyber risks, enabling cross-functional teams to remediate vulnerabilities effectively. Serving various sectors including finance, healthcare, and energy, Kenna's platform leverages predictive analytics to anticipate real-world exploitations, focusing security efforts on critical areas.

Primary

Series C in 2019
Primary makes clothes for kids and builds a better experience for busy parents to shop for them. It aims to be the most inclusive kid's clothing brand, offering high-quality essentials at affordable prices. Rather than chasing the trend, Primary offers thoughtfully designed clothing without logos, slogans, or sequins. They take a gender-neutral approach, with a broad range of colors available for babies and kids 0-12, without prescribing what is for girls or boys. It was founded in 2015 and is headquartered in New York, New York.

Edgewise Therapeutics

Series B in 2019
Edgewise Therapeutics is a clinical-stage biopharmaceutical company focused on developing innovative treatments for severe, rare muscle disorders with significant unmet medical need. It employs a holistic drug discovery approach targeting the muscle as an organ, utilizing its proprietary platform to identify precision medicines regulating key proteins in muscle tissue.

Luma Health

Series B in 2019
Founded in 2015, Luma Health develops a patient engagement platform that connects healthcare providers with patients via smart scheduling, appointment reminders, mobile intake, and care pathways. Its platform integrates with EHR systems for insights and analytics.

Entelo

Venture Round in 2019
Entelo is a recruitment platform that leverages data science and machine learning to assist companies in identifying and recruiting technical talent. Its SaaS-based solution enables talent acquisition teams to automatically rank and screen applicants using directed scoring technologies, thereby enhancing key metrics such as quality of hire, time to hire, and cost per hire. With over 600 customers across various industries, Entelo provides actionable insights and increases candidate engagement, making it a trusted partner for organizations aiming to improve their recruitment processes. Notable clients include prominent companies like Capital One, Cisco, and Netflix, which utilize Entelo's capabilities to build effective teams.

Rimeto

Series A in 2019
Rimeto LLC, founded in 2016 and based in San Francisco, California, specializes in developing application and system software that enhances employee directories and profiles. The company focuses on providing customers with detailed, people-centric tools designed to improve collaboration within the workplace. By integrating data from various enterprise systems, Rimeto enables organizations to create custom-built directories that facilitate access to information about people, projects, and teams. This integration allows for the normalization of data from public and proprietary sources, making it easier for users to search and access actionable insights. As a subsidiary of Slack Technologies, Rimeto aims to empower individuals with the resources needed to work effectively and feel connected to their colleagues.

Human Interest

Series B in 2019
Human Interest is a retirement savings provider focused on small and medium-sized businesses, offering a 401(k) platform that simplifies administration and compliance through end-to-end technology. The platform automatically creates employee accounts, syncs payroll deductions, and provides personalized investment guidance, enabling SMBs to offer affordable, easy-to-manage retirement plans; the company has served thousands of businesses across the United States and was founded in 2015 in San Francisco by Paul Sawaya and Roger Lee.

Cleave Therapeutics

Series C in 2019
Cleave Therapeutics, Inc. is a biopharmaceutical company based in San Francisco, California, founded in 2010. The company focuses on developing novel small-molecule drugs that target valosin-containing protein and other protein-degradation pathways critical for the survival of cancer cells. By creating enzyme inhibitors designed to disrupt these pathways, Cleave Therapeutics aims to address both oncological and neurodegenerative diseases. Through its innovative approach to drug discovery, the company seeks to provide effective therapeutic solutions that enhance patient outcomes in the fight against cancer.

Omada Health

Series D in 2019
Omada Health is a digital healthcare company that offers personalized programs to manage chronic conditions such as prediabetes, diabetes, hypertension, musculoskeletal issues, and behavioral health. It combines professional coaching, connected devices, real-time data, and personalized feedback to deliver clinically meaningful results.

Dstillery

Series D in 2019
Dstillery is a digital advertising technology company that develops a digital intelligence platform for brands and media partners. The platform enables brand-specific and cross-channel marketing across mobile, desktop, and video by integrating mobile location insights with desktop behaviors to optimize campaigns. It includes Dscover Maps, a geospatial insights tool that analyzes market composition by geography or location, and uses artificial intelligence to derive customer insights for audience targeting. The company emphasizes privacy-friendly options such as ID-free behavioral targeting and offers Custom AI Audiences for brand-specific targeting, supporting programmatic advertising for brands and agencies in the United States.

Percepto

Series A in 2019
Percepto is a developer of autonomous drone technology for inspection and surveillance. The company is at the forefront of redefining how industrial sites and critical infrastructure are holistically inspected and monitored, harnessing remote robotics to autonomously collect, aggregate, and analyze visual data. Leveraging its experience with Percepto Sparrow, the first deployed drone-in-a-box solution on the market, Percepto introduced Percepto AIM (Autonomous Inspection and Monitoring), the first end-to-end autonomous inspection and monitoring platform. Percepto AIM empowers the remote operation center of the future to assess risk, minimize downtime, drive efficiency, increase safety, and reduce operational costs.

Happy Returns

Venture Round in 2019
Happy Returns, Inc. is a company based in Santa Monica, California, that specializes in providing in-person return solutions for online shoppers. Founded in 2015, it operates a network of Return Bars and kiosks that allow customers to return items physically and receive immediate refunds. After the returns are processed, the company manages the logistics of shipping the items back to the respective e-commerce retailers. By offering a seamless integration of technology, service, and logistics, Happy Returns aims to enhance the returns experience for both consumers and retailers, delivering an efficient and cost-effective solution for handling returns in the online shopping landscape.

HealthJoy

Series B in 2019
HealthJoy is a healthcare technology company that provides a benefits experience and care navigation platform designed to simplify healthcare for employees and reduce costs for employers. Its AI-driven virtual assistants help users find cost-effective care options, access doctors and insurance experts, and compare care choices. The platform integrates a company's existing benefits to deliver a personalized digital benefits wallet and supports claims, health savings accounts, and prescription management. It offers on-demand online medical consultations, live healthcare concierges, and Rx savings, enabling employees to become informed healthcare shoppers. By streamlining benefits utilization and guidance, HealthJoy aims to improve employee satisfaction and contain benefit-related expenditures. The company is based in Chicago, Illinois.

Nuvaira

Series E in 2019
Nuvaira, Inc. is a medical device company based in Minneapolis, Minnesota, focused on developing innovative treatments for obstructive lung diseases, particularly chronic obstructive pulmonary disease (COPD). Founded in 2008, Nuvaira specializes in a novel catheter-based Lung Denervation System that aims to address airway nerve hyperactivity by targeting the parasympathetic innervation of the lungs. This minimally invasive procedure is designed to improve lung function, enhance exercise capacity, and elevate the quality of life for patients suffering from chronic respiratory conditions. With a commitment to advancing treatment options, Nuvaira seeks to reduce the clinical consequences associated with neural hyperactivity in conditions such as COPD and asthma.

Cato Networks

Series C in 2019
Cato Networks provides a cloud-based secure global SD-WAN and security platform that connects enterprise locations, remote users, and cloud data. The Cato Cloud integrates networking and security services, including WAN optimization, firewall, secure web gateway, threat protection, and UC optimization, delivered through a single management application. It eliminates branch appliances, reduces MPLS costs, and provides secure Internet access everywhere, enabling seamless integration of mobile users and cloud data centers into the WAN and simplifying site deployment and overall network security for distributed, mobile, and cloud-enabled enterprises.

Medigate by Claroty

Series A in 2019
Medigate by Claroty is a developer of a medical device security platform that safeguards healthcare provider networks from cyber threats. Founded in 2017, the company is headquartered in New York City and focuses on protecting all connected medical devices within these networks. Its platform utilizes deep packet inspection to decode proprietary healthcare IoT protocols, providing visibility and security for IoT and medical devices. By offering threat detection and attack prevention services, Medigate enhances the safety and privacy of hospital environments, allowing for the secure deployment of both existing and new medical devices.

HighLife

Series B in 2019
HighLife is a medical technology company specializing in Transcatheter Mitral Valve Replacement (TMVR) aimed at treating mitral valve regurgitation. Founded in 2010 by Georg Börtlein, the company is developing a minimally invasive prosthetic mitral valve designed to be implanted on a beating heart, allowing for the preservation of the native valve structure and surrounding anatomy. HighLife's innovative system facilitates a transseptal delivery through the femoral vein, enabling a reversible approach that minimizes trauma to patients during surgical procedures. The technology is currently undergoing clinical evaluation, with a focus on ensuring ease and safety of use for healthcare providers.

Ribon Therapeutics

Series B in 2019
Ribon Therapeutics, Inc. is a biotechnology company founded in 2015 and headquartered in Lexington, Massachusetts. The company focuses on developing novel therapeutics that target monoPARP proteins, which are critical regulators of cancer cell survival mechanisms. By leveraging insights from its scientific founders, Ribon is establishing a proprietary drug discovery platform aimed at investigating the molecular actions and biological functions of a specific subset of the PARP protein family. This platform enables Ribon to create a pipeline of innovative small molecule inhibitors designed to disrupt the fundamental survival capabilities of cancer cells under stress. In addition to cancer treatment, the company's research may have implications for addressing other diseases. Ribon is supported by notable life science investors, which enhances its capacity to advance its therapeutic developments.

NeoChord

Series D in 2018
NeoChord, Inc. is a medical technology company based in St. Louis Park, Minnesota, specializing in innovative solutions for degenerative mitral valve disease (DMR). Founded in 2007, the company has developed the NeoChord Artificial Chordae Delivery System, a proprietary device that enables mitral valve repair to be performed while the heart is still beating. This minimally invasive technique involves a small incision, significantly reducing recovery time and complications compared to traditional procedures that require larger chest incisions and stopping the heart. NeoChord's system addresses severe mitral regurgitation caused by elongated or ruptured chordae tendineae, allowing surgeons to effectively manage blood flow without the need for cardiopulmonary bypass.

ZypMedia

Series C in 2018
ZypMedia, Inc., also known as ZypTV, operates a demand-side platform that facilitates connections between advertisers and audiences on streaming television. Established in 2013 and headquartered in San Francisco, California, with additional offices in New York City, New Delhi, and Saint Petersburg, ZypMedia provides products such as ZypTV Enterprise and ZypTV Self-Serve, which cater to local streaming TV advertising. The company serves local media companies, media buying agencies, and brands aiming to reach local audiences at scale. By leveraging machine learning alongside human expertise, ZypMedia offers a comprehensive digital advertising technology platform designed to enhance local-focused advertising efforts. Its innovative tools help clients bridge the gap between traditional and digital media, enabling them to expand their reach and increase revenue in a rapidly changing media landscape.

Arkose Labs

Series A in 2018
Arkose Labs develops an online fraud and abuse prevention platform that protects businesses in sectors such as online marketplaces, travel, banking, social media, ticketing, and online gaming. The platform defends consumer actions against account takeover, fake account abuse, scraping, spam, and gift‑card fraud. Founded in 2015, the company is headquartered in San Mateo, California, with offices in London, Costa Rica, and Brisbane. It is recognized as a leader in bot detection and mitigation, offering a $1 million warranty for credential‑stuffing and SMS toll fraud. Arkose Labs’ AI‑powered system combines global telemetry, dynamic threat response, and a bilateral feedback loop to validate suspicious traffic and train enforcement, reducing friction for legitimate users while authenticating identities across all customer touchpoints.

Raken

Series A in 2018
Raken, Inc. is a developer of construction management software that enhances field and office applications within the construction industry. Founded in 2012 and based in Carlsbad, California, Raken offers a mobile-first platform that streamlines workflows for general and trade contractors, including those in the concrete, electrical, excavating, and mechanical sectors. Its software facilitates daily reporting, time card management, production tracking, toolbox talks, photo management, and more, allowing users to efficiently document and manage a range of construction-related tasks such as site safety, weather conditions, and equipment rental. Raken's solution connects field operations to office management, enabling professionals like superintendents and project managers to quickly record and submit essential documentation.

Luma Health

Series A in 2018
Founded in 2015, Luma Health develops a patient engagement platform that connects healthcare providers with patients via smart scheduling, appointment reminders, mobile intake, and care pathways. Its platform integrates with EHR systems for insights and analytics.

Inari Medical

Series C in 2018
Inari Medical, Inc. is a commercial-stage medical device company based in Irvine, California, that specializes in developing innovative products for the treatment of venous diseases. Founded in 2011, the company's primary focus is on venous thromboembolism, which it addresses through two key devices: the ClotTriever and the FlowTriever. The ClotTriever is designed for the minimally invasive removal of blood clots from peripheral blood vessels, specifically targeting patients with deep vein thrombosis. Meanwhile, the FlowTriever system effectively treats pulmonary embolism by removing large clots from major blood vessels without the need for thrombolytic drugs. Inari Medical primarily generates its revenue from the United States while also reaching international markets.
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