VentureSouth

mPATH is a cloud-based digital healthcare platform focused on enhancing preventive care quality metrics for healthcare systems. The platform offers an automated program that leverages evidence-based results derived from peer-reviewed medical literature. By addressing quality gaps in healthcare delivery, mPATH provides a cost-effective solution that empowers healthcare organizations to improve care and supports patients in navigating their health more effectively.

Yuva Biosciences specializes in developing cosmeceutical and pharmaceutical products aimed at addressing aging-related issues such as hair loss and skin wrinkles. The company focuses on restoring mitochondrial function, which is essential for cellular energy and health, to rejuvenate hair and skin. By leveraging mitochondrial science, Yuva Biosciences creates innovative solutions designed to counteract the symptoms of aging, enabling individuals to regain youthful vitality and appearance.

6AM City is a publishing company focused on enhancing audience participation and engagement within local communities. It operates a platform that aggregates, curates, and condenses essential local news, conversations, events, and trending topics, delivering this content through daily newsletters and social media channels. By producing brief and conversational newsletters that avoid political content, 6AM City aims to foster community involvement and dialogue. The company is dedicated to educating and activating its audience, ultimately creating a hub for local content that encourages sharing and participation, thus driving community connection and engagement.

Gradient Health is a developer of an open research platform focused on providing AI-based medical imaging diagnostics and infrastructure. The platform offers comprehensive access to a clinical sandbox, along with open-source tools and documentation that are readily available to developers. This framework facilitates the translation of research into a secure and interoperable clinical environment, enhancing the capabilities and efficiency of medical imaging diagnostics.

APPROVE is an internal, custom-branded lending programme that shows reasonable monthly payments at Every point of sale.

Emrgy is a technology company established in 2014 that specializes in designing and deploying modular and scalable hydroelectric solutions. The company focuses on developing innovative hydroelectric turbines capable of generating electricity from slow or shallow water flows, which allows power generation companies to efficiently harness energy from rivers and streams. Emrgy's offerings include advanced turbines, magnetic gearboxes, and compact hydroelectric power generators that significantly reduce energy costs. By redefining hydropower technology, Emrgy aims to enhance the reliability and cost-effectiveness of renewable energy, contributing to a shift towards distributed and intermittent energy sources.

Babylon Micro-Farms Inc., founded in 2017 and based in Charlottesville, Virginia, specializes in providing indoor farming solutions that empower individuals and communities to grow their own produce. The company offers a smart, scalable indoor farming platform designed for a variety of crops, including leafy greens, herbs, microgreens, and edible flowers. By leveraging remote management technology, Babylon Micro-Farms aims to create a decentralized network of micro-farms across North America, making sustainable hydroponic farming more accessible. Their innovative systems automate the growing process, significantly reducing water usage, food waste, and pollutants while allowing year-round cultivation. Additionally, Babylon Micro-Farms has developed low-cost micro-farms to support food-insecure populations, particularly refugees in the Middle East, highlighting their commitment to addressing food security through sustainable agriculture.

Darby provides a platform that functions as a digital vending machine for medical equipment and diagnostics, facilitating hybrid care models. This innovative solution enables remote clinicians to order last-mile tests and treatments for patients at home, reducing the need for referrals to costly care sites such as emergency departments. Additionally, Darby has developed a medical document processing platform that assists intake staff with document review by converting various document formats into structured data. This platform enhances the quality of information exchange between clinical teams and their suppliers, ensuring that users can operate efficiently while minimizing accuracy concerns.

Kiyatec, LLC is a biotechnology company based in Greenville, South Carolina, specializing in the development of advanced 3D cell-based assays for preclinical drug discovery and clinical therapy applications. The company utilizes patients' own living tumor cells to create functional 3D models that facilitate testing of various cancer therapies, enhancing the predictive accuracy of drug responses. Its innovative 3DKUBE technology platform supports in situ imaging and accommodates different scaffold materials, allowing for the modeling of complex human biology through segregated cell co-culture. Kiyatec's services include drug response profiling, toxicity evaluation, and the development of cell-based models for testing small molecules, biologic drugs, and immunotherapies. The company also engages in contract research projects and collaborates with the National Cancer Institute to advance research on cancer types such as breast cancer, glioblastoma, and lung cancer. Founded in 2005, Kiyatec aims to assist medical practitioners in identifying effective treatments for cancer patients by providing insights prior to clinical trials.

Healthycell is a developer of innovative dietary supplements that focus on effective nutrient absorption. Recognizing that traditional pill and powder supplements have low absorption rates, the company has introduced a unique MICROGEL™ technology. This advanced delivery system enables the micronutrients, vitamins, minerals, and herbal extracts to be absorbed more efficiently into the bloodstream and cells, thereby improving health outcomes. Healthycell's products cater especially to individuals who prefer to avoid pills, allowing consumers to optimize their nutrient levels and enhance overall performance. Through extensive research, Healthycell aims to revolutionize the way dietary supplements are consumed and utilized in the body, moving beyond outdated delivery methods.

Get Spiffy, Inc. is a mobile service company based in Durham, North Carolina, that specializes in on-demand car washing, detailing, nano-ceramic coating, and oil change services. Founded in 2014, the company utilizes a smartphone application that facilitates both communication and payment for its services. Get Spiffy emphasizes environmental responsibility, ensuring that all car washes are eco-friendly. Through its innovative approach, the company aims to provide convenient and efficient automotive care to customers in the Triangle area and beyond.

PunchListUSA is the first online real estate platform digitizing national home inspection data to create instant repair estimates and online service orders for homeowners, brokers, and institutional investors. The platform is powered by proprietary technology and property data to deliver home repair, renovation and lifecycle services at scale through innovative products, process automation and direct integration with industry partners. Exclusive inspection data access will power end-to-end home lifecycle services and product offerings to homeowners through the PunchListUSA marketplace in its next phase of growth.

Zylo Therapeutics, Inc. is a life sciences company based in Greenville, South Carolina, specializing in a sustained-release drug delivery system. Founded in 2017, the company has developed a delivery mechanism that employs patented hydrogel-derived nanoparticles, known as Nanopods™, to facilitate the topical administration of difficult-to-deliver therapeutic agents, including nitric oxide. This innovative system enhances drug delivery capabilities and is designed to improve the treatment of various conditions such as lupus, hair loss, joint pain, and burns. By utilizing engineered amorphous silica particles, Zylo Therapeutics aims to provide a controlled and sustained release of medications, thereby enhancing product performance and patient outcomes.

Sprockets is a technology company that specializes in AI-enabled assessment tools aimed at transforming the hiring process for hourly employees. By leveraging advanced applicant matching technology, the company evaluates potential hires based on the characteristics of a company's top-performing employees. This innovative approach utilizes AI, big data, and psycholinguistics to provide hiring managers with a quick and cost-effective way to identify the best candidates. Sprockets eliminates guesswork and reduces the frustrations often associated with hiring, ultimately aiming to decrease employee turnover and enhance organizational efficiency.

Gradient Health is a developer of an open research platform focused on providing AI-based medical imaging diagnostics and infrastructure. The platform offers comprehensive access to a clinical sandbox, along with open-source tools and documentation that are readily available to developers. This framework facilitates the translation of research into a secure and interoperable clinical environment, enhancing the capabilities and efficiency of medical imaging diagnostics.

Case Status, Inc. is a company that specializes in developing a cloud-based client engagement tool tailored for the legal services industry. Founded in 2017 by Andrew Seavers and Lauren Sturdivant, the company is headquartered in Birmingham, Alabama, with an additional office in Charleston, South Carolina. The platform aims to enhance lawyer-client communications by addressing common challenges faced by legal professionals. It offers features that allow law firms to track and measure client satisfaction, send timely updates, and facilitate effective communication with clients. By providing real-time visibility of cases and automating routine interactions, Case Status helps law firms reduce the need for frequent meetings and improve overall client relationships.

Bio 54 is focused on developing innovative solutions for managing external bleeding. The company has created a drug-device combination specifically designed to treat excessive bleeding in patients undergoing anticoagulant or anti-platelet therapies. By delivering topical anti-coagulant drugs, Bio 54 aims to enhance the quality of life for these patients, addressing a critical medical need in the management of bleeding complications.

Coworks is a coworking management software platform that aims to simplify the management and scaling of coworking spaces. Launched in 2009 in Stockholm, the company focuses on providing tools that enhance the operations of coworking space owners and operators. Its application features automation, analytics, and communication capabilities, which include a member directory, event calendar, front desk check-in, automated billing, and lead management. By leveraging these tools, Coworks seeks to optimize business operations and improve the overall community experience for members, promoting growth within coworking environments. The company is dedicated to making coworking more accessible and efficient, positioning itself as a key player in the evolving landscape of work and workplace culture.

Plantd specializes in producing sustainable building materials aimed at facilitating green and zero-carbon housing. The company utilizes industrial hemp and renewable perennial grass to create products that sequester atmospheric carbon, ensuring that it remains locked within the walls and floors of new homes. This approach not only promotes cost management but also supports carbon removal and enhances material performance. Plantd is driven by a commitment to reinventing current construction practices to contribute to a more sustainable future.

OneDigitalTrust is a B2B company that specializes in providing a software-as-a-service (SaaS) platform for estate and legacy planning. The platform is designed to assist users in managing various life stages and events, allowing them to record both assets and liabilities. It offers tools for creating state-specific estate planning documents and facilitates the management and maintenance of these plans. Additionally, the platform generates key insights and related services, enabling financial institutions to distribute it to their customers. Through these offerings, OneDigitalTrust aims to help clients safeguard and effectively distribute their legacies.

CureMint, Inc. is a provider of cloud-based procurement software tailored for the dental industry, headquartered in Durham, North Carolina. Founded in 2017, CureMint offers a comprehensive platform that manages the entire procurement lifecycle, enabling dental organizations to streamline purchasing, vendor management, and invoicing processes. Its software features modules that enhance the ordering experience for office staff while providing managers with tools for improved visibility and control over spending. The platform also facilitates the creation and management of custom formularies, allowing organizations to prioritize essential products and establish automated approval workflows. By addressing the fragmented procurement process, CureMint empowers dental practices to make informed purchasing decisions and optimize operational efficiency.

Pass It Down is a digital storytelling platform that enables users to capture, share, and preserve personal and family stories through various formats, including video, audio, text, and photos. The platform allows individuals to document their life stories by responding to prompts provided by oral historians, using their smartphones, tablets, or computers. Users can choose to share their stories publicly, with friends and family, or keep them private like a journal. Additionally, Pass It Down serves cultural institutions and brands by collecting authentic stories from customers or employees, facilitating the creation of interactive online and touchscreen exhibits that engage audiences and enhance storytelling experiences.

6AM City is a publishing company focused on enhancing audience participation and engagement within local communities. It operates a platform that aggregates, curates, and condenses essential local news, conversations, events, and trending topics, delivering this content through daily newsletters and social media channels. By producing brief and conversational newsletters that avoid political content, 6AM City aims to foster community involvement and dialogue. The company is dedicated to educating and activating its audience, ultimately creating a hub for local content that encourages sharing and participation, thus driving community connection and engagement.

Kiyatec, LLC is a biotechnology company based in Greenville, South Carolina, specializing in the development of advanced 3D cell-based assays for preclinical drug discovery and clinical therapy applications. The company utilizes patients' own living tumor cells to create functional 3D models that facilitate testing of various cancer therapies, enhancing the predictive accuracy of drug responses. Its innovative 3DKUBE technology platform supports in situ imaging and accommodates different scaffold materials, allowing for the modeling of complex human biology through segregated cell co-culture. Kiyatec's services include drug response profiling, toxicity evaluation, and the development of cell-based models for testing small molecules, biologic drugs, and immunotherapies. The company also engages in contract research projects and collaborates with the National Cancer Institute to advance research on cancer types such as breast cancer, glioblastoma, and lung cancer. Founded in 2005, Kiyatec aims to assist medical practitioners in identifying effective treatments for cancer patients by providing insights prior to clinical trials.

Trio Labs is a digital manufacturing technology company based in Durham, North Carolina, specializing in high-volume precision metal and ceramic 3D printing. Founded in 2015, the company focuses on transforming the manufacturing of precision parts by eliminating tooling costs and enhancing the throughput of established production processes. This innovative technology allows engineers to achieve the precision of traditional systems while producing metals and ceramics at increased speeds and affordability compared to conventional manufacturing methods.

GoPivot operates an employee wellness platform that focuses on enhancing health, safety, and recognition within organizations. The platform employs a point-based rewards system, enabling employees to earn points through participation in wellness activities, achieving safety milestones, and receiving recognition for their efforts. By utilizing advancements in data analytics and behavioral science, GoPivot aims to create effective corporate wellness and healthcare cost containment programs while eliminating ineffective rewards and solutions. This approach fosters a more engaged workforce and promotes a culture of wellness and safety in the workplace.

Soelect Inc. is a manufacturer of advanced solid-state battery components, specializing in SiO-C-Li composition materials produced through a solid-state process. Established in 2020 and headquartered in Greensboro, North Carolina, the company focuses on developing commercially viable solutions for solid-state batteries that utilize solid electrodes and electrolytes. Soelect's innovative LiX technology features a lithium metal anode designed for fast charging capabilities, making it suitable for a diverse range of applications including electric vehicles, portable electronics, power tools, drones, aircraft, spacecraft, and tactical defense equipment. By offering high energy density and efficiency, Soelect aims to provide cost-effective alternatives to traditional lithium-ion batteries, catering to manufacturers in various sectors.

imagine.io is a 3D content creation platform that enables furniture and textile manufacturers to produce high-quality, photo-realistic 3D imagery. The platform automates the image production process, catering to e-commerce, social media, and catalog needs. Users can create a diverse range of content, including silhouette and lifestyle images, augmented reality experiences, videos, and immersive, shoppable environments, all without requiring a background in three-dimensional design or engineering. This approach allows for enhanced speed and flexibility in interactive 3D photography, ultimately streamlining the content creation process for businesses in the furniture and textile industries.

Redbud Labs, Inc. specializes in the development and manufacturing of MEMS and microfluidics technologies tailored for the life science industry. The company produces actuated surface-attached posts films, which facilitate the manipulation of fluids, cells, and reagents at the microscale, thereby enhancing mixing efficiency and reducing assay times. Additionally, Redbud Labs is known for its innovative MXR, the first fully modular microfluidic mixer, utilized by leading biotechnology firms to enhance assay performance. The company offers cartridge-based automated sample preparation platforms, which simplify laboratory workflows while maintaining high performance. Founded in 2010 and based in Chapel Hill, North Carolina, Redbud Labs draws on advanced research from the University of North Carolina to provide solutions that address complex microfluidic challenges in research, drug discovery, and diagnostics.

Sprockets is a technology company that specializes in AI-enabled assessment tools aimed at transforming the hiring process for hourly employees. By leveraging advanced applicant matching technology, the company evaluates potential hires based on the characteristics of a company's top-performing employees. This innovative approach utilizes AI, big data, and psycholinguistics to provide hiring managers with a quick and cost-effective way to identify the best candidates. Sprockets eliminates guesswork and reduces the frustrations often associated with hiring, ultimately aiming to decrease employee turnover and enhance organizational efficiency.

Babylon Micro-Farms Inc., founded in 2017 and based in Charlottesville, Virginia, specializes in providing indoor farming solutions that empower individuals and communities to grow their own produce. The company offers a smart, scalable indoor farming platform designed for a variety of crops, including leafy greens, herbs, microgreens, and edible flowers. By leveraging remote management technology, Babylon Micro-Farms aims to create a decentralized network of micro-farms across North America, making sustainable hydroponic farming more accessible. Their innovative systems automate the growing process, significantly reducing water usage, food waste, and pollutants while allowing year-round cultivation. Additionally, Babylon Micro-Farms has developed low-cost micro-farms to support food-insecure populations, particularly refugees in the Middle East, highlighting their commitment to addressing food security through sustainable agriculture.

Seal the Seasons, Inc. is a frozen food company based in Chapel Hill, North Carolina, founded in 2014. The company specializes in processing, freezing, marketing, and distributing locally grown fruits and vegetables to both consumers and institutional customers. By partnering with local farmers across the United States, Seal the Seasons creates a robust local supply chain that allows them to offer products year-round, including frozen blueberries, broccoli, spinach, and various fruit medleys. The company distributes its products to grocery stores nationwide, enabling consumers to access nutritious local food while supporting their communities. More than 90% of the product costs are returned to rural communities, empowering local farmers to increase seasonal planting to meet year-round demand. Seal the Seasons aims to provide high-quality local produce while catering to the growing consumer demand for accessible, sustainable food options.

Aperiomics, Inc. is a biotechnology company based in Sterling, Virginia, specializing in pathogen detection services for the animal screening, agricultural testing, and human diagnostics industries. Founded in 2013 and initially known as NextGen Diagnostics, the company changed its name in 2014. Aperiomics utilizes advanced sequencing technologies and a proprietary informatics pipeline to identify a wide range of pathogens, including viral, bacterial, fungal, and parasitic organisms, through a single test. By employing Deep Shotgun Metagenomic Sequencing and leveraging a comprehensive database of over 37,000 microbes, Aperiomics enables medical professionals to identify infections that may be missed by conventional testing methods. This innovative approach has aided many patients suffering from unexplained illnesses by providing accurate diagnoses and facilitating effective treatment pathways. Recognized for its contributions to the field, Aperiomics received accolades such as Life Science Innovator of the Year in 2016 and International Start Up of the Year in 2018.

Altis Biosystems, LLC is a biotechnology company specializing in the development of innovative stem cell technologies aimed at enhancing research in human biology. Established in 2015 and based in Chapel Hill, North Carolina, the company has created a patent-pending system known as RepliGut, which effectively recreates the human intestinal epithelium and colonic epithelium. This advanced technology enables the generation of a layer of human or animal intestinal stem and differentiated cells from both the small and large intestines. Altis Biosystems' products are primarily utilized in preclinical studies for disease modeling, precision medicine, microbiome research, and compound screening, serving the needs of pharmaceutical and biotechnology companies. By utilizing normal human intestinal tissue, the company aims to improve drug development processes while minimizing reliance on animal testing.

PunchListUSA is the first online real estate platform digitizing national home inspection data to create instant repair estimates and online service orders for homeowners, brokers, and institutional investors. The platform is powered by proprietary technology and property data to deliver home repair, renovation and lifecycle services at scale through innovative products, process automation and direct integration with industry partners. Exclusive inspection data access will power end-to-end home lifecycle services and product offerings to homeowners through the PunchListUSA marketplace in its next phase of growth.

We’re creating a world where it’s easy to give back to causes you care about, without spending extra money, minutes, or mental load

6AM City is a publishing company focused on enhancing audience participation and engagement within local communities. It operates a platform that aggregates, curates, and condenses essential local news, conversations, events, and trending topics, delivering this content through daily newsletters and social media channels. By producing brief and conversational newsletters that avoid political content, 6AM City aims to foster community involvement and dialogue. The company is dedicated to educating and activating its audience, ultimately creating a hub for local content that encourages sharing and participation, thus driving community connection and engagement.

Reveal Mobile, Inc. is a company that specializes in location-based marketing and analytics, catering to agencies, brands, media companies, and app publishers. Founded in 2004 and based in Raleigh, North Carolina, the company operates a platform that includes solutions such as VISIT Local, which offers foot traffic attribution and audience building, and VISIT Match, designed for instant audience scaling. Additionally, Reveal Mobile provides VISIT Data, a customizable location-data solution for enterprise applications. The platform facilitates the creation of targeted audience segments and enables clients to reach these audiences through various digital advertising channels, including social media. With a strong emphasis on privacy compliance, Reveal Mobile is a member of the Network Advertising Initiative and undergoes annual privacy certifications, ensuring that its services adhere to industry standards. The company's user-friendly interface simplifies audience analytics and post-campaign reporting, allowing clients to effectively measure the impact of their marketing efforts on foot traffic.

Get Spiffy, Inc. is a mobile service company based in Durham, North Carolina, that specializes in on-demand car washing, detailing, nano-ceramic coating, and oil change services. Founded in 2014, the company utilizes a smartphone application that facilitates both communication and payment for its services. Get Spiffy emphasizes environmental responsibility, ensuring that all car washes are eco-friendly. Through its innovative approach, the company aims to provide convenient and efficient automotive care to customers in the Triangle area and beyond.

Altis Biosystems, LLC is a biotechnology company specializing in the development of innovative stem cell technologies aimed at enhancing research in human biology. Established in 2015 and based in Chapel Hill, North Carolina, the company has created a patent-pending system known as RepliGut, which effectively recreates the human intestinal epithelium and colonic epithelium. This advanced technology enables the generation of a layer of human or animal intestinal stem and differentiated cells from both the small and large intestines. Altis Biosystems' products are primarily utilized in preclinical studies for disease modeling, precision medicine, microbiome research, and compound screening, serving the needs of pharmaceutical and biotechnology companies. By utilizing normal human intestinal tissue, the company aims to improve drug development processes while minimizing reliance on animal testing.

PunchListUSA is the first online real estate platform digitizing national home inspection data to create instant repair estimates and online service orders for homeowners, brokers, and institutional investors. The platform is powered by proprietary technology and property data to deliver home repair, renovation and lifecycle services at scale through innovative products, process automation and direct integration with industry partners. Exclusive inspection data access will power end-to-end home lifecycle services and product offerings to homeowners through the PunchListUSA marketplace in its next phase of growth.

6AM City is a publishing company focused on enhancing audience participation and engagement within local communities. It operates a platform that aggregates, curates, and condenses essential local news, conversations, events, and trending topics, delivering this content through daily newsletters and social media channels. By producing brief and conversational newsletters that avoid political content, 6AM City aims to foster community involvement and dialogue. The company is dedicated to educating and activating its audience, ultimately creating a hub for local content that encourages sharing and participation, thus driving community connection and engagement.

Zylo Therapeutics, Inc. is a life sciences company based in Greenville, South Carolina, specializing in a sustained-release drug delivery system. Founded in 2017, the company has developed a delivery mechanism that employs patented hydrogel-derived nanoparticles, known as Nanopods™, to facilitate the topical administration of difficult-to-deliver therapeutic agents, including nitric oxide. This innovative system enhances drug delivery capabilities and is designed to improve the treatment of various conditions such as lupus, hair loss, joint pain, and burns. By utilizing engineered amorphous silica particles, Zylo Therapeutics aims to provide a controlled and sustained release of medications, thereby enhancing product performance and patient outcomes.

Outdoor Access, Inc. operates an online platform that connects outdoor enthusiasts, such as hunters, anglers, and campers, with landowners looking to lease their private land for recreational activities. Established in 2016 and based in Richmond, Virginia, the company aims to make outdoor experiences more accessible and affordable while providing landowners with a means to monetize their properties. The platform facilitates a marketplace where users can discover unique opportunities for various outdoor pursuits, including hunting, fishing, and hiking. Outdoor Access emphasizes ethical outdoor practices and encourages its members to respect the rules set by landowners. Additionally, the company promotes outdoor traditions by allowing children under 18 to participate for free.

Aperiomics, Inc. is a biotechnology company based in Sterling, Virginia, specializing in pathogen detection services for the animal screening, agricultural testing, and human diagnostics industries. Founded in 2013 and initially known as NextGen Diagnostics, the company changed its name in 2014. Aperiomics utilizes advanced sequencing technologies and a proprietary informatics pipeline to identify a wide range of pathogens, including viral, bacterial, fungal, and parasitic organisms, through a single test. By employing Deep Shotgun Metagenomic Sequencing and leveraging a comprehensive database of over 37,000 microbes, Aperiomics enables medical professionals to identify infections that may be missed by conventional testing methods. This innovative approach has aided many patients suffering from unexplained illnesses by providing accurate diagnoses and facilitating effective treatment pathways. Recognized for its contributions to the field, Aperiomics received accolades such as Life Science Innovator of the Year in 2016 and International Start Up of the Year in 2018.

HelloPackage is a sophisticated package management system developed by Package Solutions, Inc. that addresses the logistics challenges faced by high-density environments, particularly apartment communities. The platform integrates carriers, apartment communities, retailers, and residents, enhancing last-mile logistics efficiency. Leveraging machine learning and artificial intelligence, HelloPackage optimizes package density and throughput within the limited space commonly available in apartment complexes. In addition to serving apartment communities, the system can also be applied in various settings, including student housing, office complexes, retail spaces, hotels, and convention centers, thereby providing flexible and cost-effective locker-less package services.

Avadim Health is a healthcare and wellness company based in Asheville, North Carolina, specializing in the development, manufacturing, and marketing of topical products for both institutional care and consumer markets. Utilizing its Bionome Engineered Platform, the company focuses on enhancing topical immune health, neuromuscular health, and skin barrier health. Avadim Health offers a range of products designed to alleviate pain, infections, muscle cramps, spasms, symptoms of restless leg syndrome, and joint discomfort. These products are distributed to various retail outlets, including grocery stores and pharmacies, as well as acute-care hospitals, nursing homes, and other long-term care facilities. Additionally, the company provides consulting services and sells its products online. Founded in 2007 and initially known as Avadim Technologies, the company rebranded to Avadim Health in September 2018.

Get Spiffy, Inc. is a mobile service company based in Durham, North Carolina, that specializes in on-demand car washing, detailing, nano-ceramic coating, and oil change services. Founded in 2014, the company utilizes a smartphone application that facilitates both communication and payment for its services. Get Spiffy emphasizes environmental responsibility, ensuring that all car washes are eco-friendly. Through its innovative approach, the company aims to provide convenient and efficient automotive care to customers in the Triangle area and beyond.

Treis Blockchain, providing distributed blockchain verification services and solutions consulting. The company processes digital currency and other blockchain transactions. It data mines cryptocurrency, preventing cyberattacks in the financial and retail industries. Michael Bolick established the company in Greer, South Carolina in 2017.

Zylo Therapeutics, Inc. is a life sciences company based in Greenville, South Carolina, specializing in a sustained-release drug delivery system. Founded in 2017, the company has developed a delivery mechanism that employs patented hydrogel-derived nanoparticles, known as Nanopods™, to facilitate the topical administration of difficult-to-deliver therapeutic agents, including nitric oxide. This innovative system enhances drug delivery capabilities and is designed to improve the treatment of various conditions such as lupus, hair loss, joint pain, and burns. By utilizing engineered amorphous silica particles, Zylo Therapeutics aims to provide a controlled and sustained release of medications, thereby enhancing product performance and patient outcomes.

A marketplace and ad placement tool that allows audience owners to monetize the value they’ve created

Kiyatec, LLC is a biotechnology company based in Greenville, South Carolina, specializing in the development of advanced 3D cell-based assays for preclinical drug discovery and clinical therapy applications. The company utilizes patients' own living tumor cells to create functional 3D models that facilitate testing of various cancer therapies, enhancing the predictive accuracy of drug responses. Its innovative 3DKUBE technology platform supports in situ imaging and accommodates different scaffold materials, allowing for the modeling of complex human biology through segregated cell co-culture. Kiyatec's services include drug response profiling, toxicity evaluation, and the development of cell-based models for testing small molecules, biologic drugs, and immunotherapies. The company also engages in contract research projects and collaborates with the National Cancer Institute to advance research on cancer types such as breast cancer, glioblastoma, and lung cancer. Founded in 2005, Kiyatec aims to assist medical practitioners in identifying effective treatments for cancer patients by providing insights prior to clinical trials.

LUMINELLE, developed by UVision360, offers a visual biopsy system designed for the diagnosis of uterine disorders in an office setting, minimizing the need for anesthesia. This innovative endoscopy technology streamlines hysteroscopy and cystoscopy procedures, providing a cost-effective alternative for both patients and medical practices. The system enhances convenience for physicians, patients, and staff, while also optimizing revenue for healthcare facilities. By facilitating a shift towards office-based procedures, LUMINELLE aims to improve the efficiency and accessibility of diagnostic care in gynecology.

Vendor Registry is a cloud-based platform designed to streamline vendor registration services for local governments. The company aims to simplify the process of doing business with state and local institutions by reducing repetitive paperwork and automating workflows that have traditionally been paper-intensive. This approach not only saves time for both vendors and government agencies but also fosters competitive bidding, enabling local businesses to generate new revenue opportunities. By centralizing the purchasing process, Vendor Registry creates a more efficient marketplace that benefits both suppliers and government entities, ultimately leading to reduced costs for taxpayer-funded purchasing departments. The platform serves as a vital link between vendors and local governments, enhancing compliance and facilitating better business practices.

ThreatSwitch, Inc. is a provider of business-to-business security compliance software designed to assist organizations in managing their industrial security compliance programs. Founded in 2016 and headquartered in Charlotte, North Carolina, the company's platform allows security professionals to oversee various aspects of personnel management, including access, eligibility, investigations, and training progress. It facilitates self-reporting by employees and automates the tracking of user activities while enabling the creation and management of access requests for visitors. By streamlining compliance processes, ThreatSwitch helps organizations reduce costs, enhance employee engagement in security protocols, and mitigate overall risk. The platform is utilized by facility security officers, security specialists, information system security officers, and other security professionals across industries subject to stringent security regulations.

KWIPPED, Inc. operates an online marketplace that specializes in B2B equipment rental and leasing. Founded in 2011 and based in Wilmington, North Carolina, the platform connects businesses with a global network of equipment suppliers, making it easier to locate and rent specialized equipment for various commercial applications. KWIPPED's technology not only streamlines the sourcing process but also aims to reduce risk and ensure quality, fostering trusted relationships between renters and suppliers. By offering a comprehensive selection of rental equipment, KWIPPED enhances accessibility for businesses seeking reliable solutions for their equipment needs.

Sprockets is a technology company that specializes in AI-enabled assessment tools aimed at transforming the hiring process for hourly employees. By leveraging advanced applicant matching technology, the company evaluates potential hires based on the characteristics of a company's top-performing employees. This innovative approach utilizes AI, big data, and psycholinguistics to provide hiring managers with a quick and cost-effective way to identify the best candidates. Sprockets eliminates guesswork and reduces the frustrations often associated with hiring, ultimately aiming to decrease employee turnover and enhance organizational efficiency.

Resiliency Technologies, Inc. operates Sharpen, a cloud-based technology and analytics platform focused on mental health and wellness. Headquartered in Spartanburg, South Carolina, the platform tracks individual and group behaviors to generate targeted recommendations through real-time analytics. Sharpen provides educational resources aimed at addressing the root causes of mental health issues such as stress, depression, and obesity. It facilitates connections among researchers, educators, and corporations to deliver evidence-based interventions, thereby supporting the prevention, early intervention, and treatment of mental health and substance use disorders. Founded in 2014, Resiliency Technologies brings over a century of expertise in the medical technology field to its mission of promoting mental well-being.

Reveal Mobile, Inc. is a company that specializes in location-based marketing and analytics, catering to agencies, brands, media companies, and app publishers. Founded in 2004 and based in Raleigh, North Carolina, the company operates a platform that includes solutions such as VISIT Local, which offers foot traffic attribution and audience building, and VISIT Match, designed for instant audience scaling. Additionally, Reveal Mobile provides VISIT Data, a customizable location-data solution for enterprise applications. The platform facilitates the creation of targeted audience segments and enables clients to reach these audiences through various digital advertising channels, including social media. With a strong emphasis on privacy compliance, Reveal Mobile is a member of the Network Advertising Initiative and undergoes annual privacy certifications, ensuring that its services adhere to industry standards. The company's user-friendly interface simplifies audience analytics and post-campaign reporting, allowing clients to effectively measure the impact of their marketing efforts on foot traffic.

ProAxion, Inc. is a manufacturer of cloud-connected sensors aimed at enhancing predictive maintenance for industrial machinery. The company has developed TACTIX, a tool designed to remotely monitor the health of rotating machines, thereby helping to prevent unexpected failures of mission-critical equipment. By utilizing low-power sensors and cloud computing technologies, ProAxion enables industrial facilities to improve their uptime and reliability while optimizing the total cost of operations and maintenance. Founded in 2015 and based in Cary, North Carolina, ProAxion's innovative solutions contribute to data-driven operations, addressing the needs of millions of machines integral to societal functions and advancing the Industrial Internet of Things.

Proterra Inc. is a manufacturer of zero-emission electric buses, primarily focused on providing sustainable transportation solutions for public and commercial transit. Founded in 2004 and headquartered in Burlingame, California, with additional offices in Greenville, South Carolina, and City of Industry, California, Proterra designs its products, including 35-foot and 40-foot electric buses, to meet the diverse needs of urban and regional transit routes. The company's Catalyst platform is noted for its modularity, allowing it to adapt to various operational demands while delivering high energy efficiency. Proterra also offers a broad range of services, including vehicle electrification solutions, fleet planning, charging infrastructure, and comprehensive vehicle maintenance programs. By facilitating the transition away from fossil fuels, Proterra aims to enhance environmental quality and reduce operational costs for fleet operators, contributing to significant reductions in greenhouse gas emissions.

Emrgy is a technology company established in 2014 that specializes in designing and deploying modular and scalable hydroelectric solutions. The company focuses on developing innovative hydroelectric turbines capable of generating electricity from slow or shallow water flows, which allows power generation companies to efficiently harness energy from rivers and streams. Emrgy's offerings include advanced turbines, magnetic gearboxes, and compact hydroelectric power generators that significantly reduce energy costs. By redefining hydropower technology, Emrgy aims to enhance the reliability and cost-effectiveness of renewable energy, contributing to a shift towards distributed and intermittent energy sources.

Ecomdash is a software-as-a-service company that provides automation solutions for backend operations tailored to ecommerce sellers. The platform is designed to streamline and integrate various processes for omnichannel retailers, including inventory management, sales orders, product listings, and shipping across multiple marketplaces such as Amazon and eBay, as well as ecommerce platforms like Shopify. By utilizing Ecomdash, online retailers can enhance their operational efficiency, thereby saving time, increasing sales, and improving customer satisfaction.

Vendor Registry is a cloud-based platform designed to streamline vendor registration services for local governments. The company aims to simplify the process of doing business with state and local institutions by reducing repetitive paperwork and automating workflows that have traditionally been paper-intensive. This approach not only saves time for both vendors and government agencies but also fosters competitive bidding, enabling local businesses to generate new revenue opportunities. By centralizing the purchasing process, Vendor Registry creates a more efficient marketplace that benefits both suppliers and government entities, ultimately leading to reduced costs for taxpayer-funded purchasing departments. The platform serves as a vital link between vendors and local governments, enhancing compliance and facilitating better business practices.

6AM City is a publishing company focused on enhancing audience participation and engagement within local communities. It operates a platform that aggregates, curates, and condenses essential local news, conversations, events, and trending topics, delivering this content through daily newsletters and social media channels. By producing brief and conversational newsletters that avoid political content, 6AM City aims to foster community involvement and dialogue. The company is dedicated to educating and activating its audience, ultimately creating a hub for local content that encourages sharing and participation, thus driving community connection and engagement.

Get Spiffy, Inc. is a mobile service company based in Durham, North Carolina, that specializes in on-demand car washing, detailing, nano-ceramic coating, and oil change services. Founded in 2014, the company utilizes a smartphone application that facilitates both communication and payment for its services. Get Spiffy emphasizes environmental responsibility, ensuring that all car washes are eco-friendly. Through its innovative approach, the company aims to provide convenient and efficient automotive care to customers in the Triangle area and beyond.

Cirtemo specializes in the development of advanced optical filter technology aimed at enhancing chemical detection capabilities. The company's innovative multivariate optical elements utilize microscopic sensors to provide increased sensitivity and specificity in analyte detection, surpassing the limitations of traditional narrow band pass filters. By partnering with Optical Filter Manufacturers and Optical Component and System Manufacturers, Cirtemo enables these partners to offer differentiated products while maintaining a strong intellectual property position. This collaboration empowers clients to address new applications in chemical measurement that were previously unattainable, ultimately improving detection limits and minimizing crosstalk in their analytical processes.

Nirvana Science, Inc. is a company based in Research Triangle Park, North Carolina, focused on developing synthetic bacteriochlorins and fluorescent dyes. Established in 2011, it specializes in creating innovative fluorescent dyes with ultra-narrow emissions, designed to enhance the efficiency of fluorescence-based medical diagnostics and imaging systems. These advanced dyes improve multiplexing capabilities, which are increasingly desired by researchers, leading to more accurate data for medical professionals by simplifying detection processes.

OBMedical Company specializes in the development, manufacture, and sale of external maternal-fetal monitoring systems designed for laboring women. The company's flagship product, the LaborView sensor system, is a wireless electrode-based device that measures labor contractions and monitors the heart rates of both mothers and infants. This innovative system allows for greater mobility during labor by providing signal capture and digital signal processing. By enhancing the accuracy and comfort of monitoring, OBMedical aims to improve health outcomes and safety for mothers and their babies during pregnancy and labor. Founded in 2012 and headquartered in Newberry, Florida, with an additional office in Norcross, Georgia, OBMedical was sold to Philips Healthcare in late 2018. The technology behind the LaborView system was developed in collaboration with the University of Florida and Convergent Engineering, making it a significant advancement in obstetric care.

Atlas Organics Inc. is a company that specializes in organics recycling, focusing on the collection and recycling of food and yard waste. Founded in 2013 and headquartered in Spartanburg, South Carolina, Atlas Organics operates in regions including San Antonio, Texas, and various areas in South Carolina, North Carolina, and Tennessee. The company partners with municipalities to collect food waste from various sources such as grocery stores, hospitals, and schools, thereby advancing sustainability initiatives. Atlas Organics transforms this waste into organic compost products suitable for agricultural, landscaping, and home gardening applications. By promoting the "table to farm" movement, Atlas Organics helps its clients achieve their sustainability goals while diverting compostable materials from landfills. The company's composting facilities produce valuable nutrients that enhance soil health, supporting both environmental and agricultural practices.

Physcient, Inc. is a manufacturer of surgical instruments, specializing in the Differential Dissector, which is designed for blunt dissection. This device is utilized in various surgical fields, including plastic surgery and general surgery procedures such as thoracic, gastrointestinal, gynecological, urological, peripheral vascular, and orthopedic surgeries. Founded in 2007 and headquartered in Durham, North Carolina, Physcient focuses on developing modern technology for hand-held surgical instruments that facilitate quicker recovery without altering existing surgical techniques. The company's founders bring over 75 years of combined experience in advancing technologies within the life and health sciences.

Emergo Therapeutics, Inc. is a pharmaceutical company based in Durham, North Carolina, founded in 2016. The company focuses on developing therapeutic drugs aimed at modulating inflammatory cytokines and enhancing immune system function. Its primary product in development is norketotifen, which is intended for the treatment of uncomplicated influenza and flu-like illnesses. Emergo Therapeutics seeks to reduce the production of inflammatory cytokines from mast cells, with a broader goal of addressing various infectious diseases and improving health outcomes related to inflammation.

CharlestonPharma, LLC is dedicated to developing innovative therapeutic products aimed at cancer patients and healthcare providers. The company specializes in creating fully human monoclonal antibodies that target nucleolin, a cell surface receptor associated with various cancers. With an exclusive worldwide license from the Medical University of South Carolina for eight specific antibodies and the technology to produce additional antibodies, CharlestonPharma focuses on demonstrating the preclinical efficacy and safety of its anti-nucleolin antibodies. Laboratory studies indicate that these antibodies can selectively kill cancer cells while sparing normal cells, minimizing toxicity. Additionally, the company is working on diagnostic tests that utilize cell surface nucleolin to aid in the prognosis and diagnosis of malignant diseases. CharlestonPharma operates from the Charleston Innovation Center, where its research aims to identify the most promising antibodies for future in vivo studies. The company was incorporated in 2010 and is based in Charleston, South Carolina.

Brightfield Transportation Solutions, Inc. manufactures and sells electric vehicle charging stations, focusing on solar-powered technology. Established in 2005 and based in Asheville, North Carolina, the company serves a variety of markets, including electric utilities, workplaces, retail spaces, universities, and municipalities. Brightfield specializes in the installation of DC fast chargers and Level 2 chargers, collaborating with notable partners such as Nissan, BMW, EVgo, the U.S. Department of Energy, and the North Carolina Department of Commerce. Its operations encompass the planning, siting, installation, operation, and maintenance of these electric vehicle charging stations, contributing to the growth of sustainable transportation infrastructure.

ThreatSwitch, Inc. is a provider of business-to-business security compliance software designed to assist organizations in managing their industrial security compliance programs. Founded in 2016 and headquartered in Charlotte, North Carolina, the company's platform allows security professionals to oversee various aspects of personnel management, including access, eligibility, investigations, and training progress. It facilitates self-reporting by employees and automates the tracking of user activities while enabling the creation and management of access requests for visitors. By streamlining compliance processes, ThreatSwitch helps organizations reduce costs, enhance employee engagement in security protocols, and mitigate overall risk. The platform is utilized by facility security officers, security specialists, information system security officers, and other security professionals across industries subject to stringent security regulations.

Seurat Technologies, based in Mountain View, California, specializes in innovative 3D printing services focused on metal manufacturing. Founded in 2015, the company has developed Area Printing, a next-generation technology designed for high-volume, decarbonized industrial production. This approach effectively decouples resolution from speed, allowing for a scalable process that can rival traditional manufacturing methods. Seurat's technology, originally developed at Lawrence Livermore National Laboratory, is backed by over 130 patents granted and pending. The company aims to provide metal parts for original equipment manufacturers (OEMs) through long-term contracts, utilizing techniques such as direct metal writing and selective laser melting to enable cost-effective production at scale.

OBMedical Company specializes in the development, manufacture, and sale of external maternal-fetal monitoring systems designed for laboring women. The company's flagship product, the LaborView sensor system, is a wireless electrode-based device that measures labor contractions and monitors the heart rates of both mothers and infants. This innovative system allows for greater mobility during labor by providing signal capture and digital signal processing. By enhancing the accuracy and comfort of monitoring, OBMedical aims to improve health outcomes and safety for mothers and their babies during pregnancy and labor. Founded in 2012 and headquartered in Newberry, Florida, with an additional office in Norcross, Georgia, OBMedical was sold to Philips Healthcare in late 2018. The technology behind the LaborView system was developed in collaboration with the University of Florida and Convergent Engineering, making it a significant advancement in obstetric care.

Kiyatec, LLC is a biotechnology company based in Greenville, South Carolina, specializing in the development of advanced 3D cell-based assays for preclinical drug discovery and clinical therapy applications. The company utilizes patients' own living tumor cells to create functional 3D models that facilitate testing of various cancer therapies, enhancing the predictive accuracy of drug responses. Its innovative 3DKUBE technology platform supports in situ imaging and accommodates different scaffold materials, allowing for the modeling of complex human biology through segregated cell co-culture. Kiyatec's services include drug response profiling, toxicity evaluation, and the development of cell-based models for testing small molecules, biologic drugs, and immunotherapies. The company also engages in contract research projects and collaborates with the National Cancer Institute to advance research on cancer types such as breast cancer, glioblastoma, and lung cancer. Founded in 2005, Kiyatec aims to assist medical practitioners in identifying effective treatments for cancer patients by providing insights prior to clinical trials.

KWIPPED, Inc. operates an online marketplace that specializes in B2B equipment rental and leasing. Founded in 2011 and based in Wilmington, North Carolina, the platform connects businesses with a global network of equipment suppliers, making it easier to locate and rent specialized equipment for various commercial applications. KWIPPED's technology not only streamlines the sourcing process but also aims to reduce risk and ensure quality, fostering trusted relationships between renters and suppliers. By offering a comprehensive selection of rental equipment, KWIPPED enhances accessibility for businesses seeking reliable solutions for their equipment needs.

Vendor Registry is a cloud-based platform designed to streamline vendor registration services for local governments. The company aims to simplify the process of doing business with state and local institutions by reducing repetitive paperwork and automating workflows that have traditionally been paper-intensive. This approach not only saves time for both vendors and government agencies but also fosters competitive bidding, enabling local businesses to generate new revenue opportunities. By centralizing the purchasing process, Vendor Registry creates a more efficient marketplace that benefits both suppliers and government entities, ultimately leading to reduced costs for taxpayer-funded purchasing departments. The platform serves as a vital link between vendors and local governments, enhancing compliance and facilitating better business practices.

Reveal Mobile, Inc. is a company that specializes in location-based marketing and analytics, catering to agencies, brands, media companies, and app publishers. Founded in 2004 and based in Raleigh, North Carolina, the company operates a platform that includes solutions such as VISIT Local, which offers foot traffic attribution and audience building, and VISIT Match, designed for instant audience scaling. Additionally, Reveal Mobile provides VISIT Data, a customizable location-data solution for enterprise applications. The platform facilitates the creation of targeted audience segments and enables clients to reach these audiences through various digital advertising channels, including social media. With a strong emphasis on privacy compliance, Reveal Mobile is a member of the Network Advertising Initiative and undergoes annual privacy certifications, ensuring that its services adhere to industry standards. The company's user-friendly interface simplifies audience analytics and post-campaign reporting, allowing clients to effectively measure the impact of their marketing efforts on foot traffic.

LUMINELLE, developed by UVision360, offers a visual biopsy system designed for the diagnosis of uterine disorders in an office setting, minimizing the need for anesthesia. This innovative endoscopy technology streamlines hysteroscopy and cystoscopy procedures, providing a cost-effective alternative for both patients and medical practices. The system enhances convenience for physicians, patients, and staff, while also optimizing revenue for healthcare facilities. By facilitating a shift towards office-based procedures, LUMINELLE aims to improve the efficiency and accessibility of diagnostic care in gynecology.

6AM City is a publishing company focused on enhancing audience participation and engagement within local communities. It operates a platform that aggregates, curates, and condenses essential local news, conversations, events, and trending topics, delivering this content through daily newsletters and social media channels. By producing brief and conversational newsletters that avoid political content, 6AM City aims to foster community involvement and dialogue. The company is dedicated to educating and activating its audience, ultimately creating a hub for local content that encourages sharing and participation, thus driving community connection and engagement.

ProAxion, Inc. is a manufacturer of cloud-connected sensors aimed at enhancing predictive maintenance for industrial machinery. The company has developed TACTIX, a tool designed to remotely monitor the health of rotating machines, thereby helping to prevent unexpected failures of mission-critical equipment. By utilizing low-power sensors and cloud computing technologies, ProAxion enables industrial facilities to improve their uptime and reliability while optimizing the total cost of operations and maintenance. Founded in 2015 and based in Cary, North Carolina, ProAxion's innovative solutions contribute to data-driven operations, addressing the needs of millions of machines integral to societal functions and advancing the Industrial Internet of Things.

PharmRight Corporation, founded in 2013 and based in Charleston, South Carolina, focuses on designing and developing medical devices aimed at enhancing medication adherence at home. The company's flagship product, Livi, is an automated pill dispenser that helps users manage their medication schedules independently. Livi is designed to support both patients and their caregivers, simplifying the process of handling multiple medications while offering crucial assistance to caregivers. In addition to its innovative devices, PharmRight also provides a range of prescribed and non-prescribed medicines and other drugs, reinforcing its commitment to improving health outcomes through better medication management.

ProctorFree, Inc. offers an automated online proctoring service designed to enhance academic integrity in online assessments. Founded in 2012 and based in Huntersville, North Carolina, the company utilizes facial recognition technology for student authentication and ensures continuous identity verification throughout the exam using a standard computer, webcam, and microphone. The software monitors for suspicious behavior that may indicate cheating and generates a TrustScore report for faculty shortly after the exam concludes, providing detailed insights and video recordings of the testing session. ProctorFree's solution aims to be a cost-effective and convenient alternative to traditional proctoring methods, ultimately improving the online education experience by fostering trust and integrity, which can lead to increased enrollment and a better public perception of online learning.

Proterra Inc. is a manufacturer of zero-emission electric buses, primarily focused on providing sustainable transportation solutions for public and commercial transit. Founded in 2004 and headquartered in Burlingame, California, with additional offices in Greenville, South Carolina, and City of Industry, California, Proterra designs its products, including 35-foot and 40-foot electric buses, to meet the diverse needs of urban and regional transit routes. The company's Catalyst platform is noted for its modularity, allowing it to adapt to various operational demands while delivering high energy efficiency. Proterra also offers a broad range of services, including vehicle electrification solutions, fleet planning, charging infrastructure, and comprehensive vehicle maintenance programs. By facilitating the transition away from fossil fuels, Proterra aims to enhance environmental quality and reduce operational costs for fleet operators, contributing to significant reductions in greenhouse gas emissions.

Emrgy is a technology company established in 2014 that specializes in designing and deploying modular and scalable hydroelectric solutions. The company focuses on developing innovative hydroelectric turbines capable of generating electricity from slow or shallow water flows, which allows power generation companies to efficiently harness energy from rivers and streams. Emrgy's offerings include advanced turbines, magnetic gearboxes, and compact hydroelectric power generators that significantly reduce energy costs. By redefining hydropower technology, Emrgy aims to enhance the reliability and cost-effectiveness of renewable energy, contributing to a shift towards distributed and intermittent energy sources.

Get Spiffy, Inc. is a mobile service company based in Durham, North Carolina, that specializes in on-demand car washing, detailing, nano-ceramic coating, and oil change services. Founded in 2014, the company utilizes a smartphone application that facilitates both communication and payment for its services. Get Spiffy emphasizes environmental responsibility, ensuring that all car washes are eco-friendly. Through its innovative approach, the company aims to provide convenient and efficient automotive care to customers in the Triangle area and beyond.

TiO is a developer of customizable smart home solutions, primarily aimed at builders. The company specializes in home automation and control systems that enhance comfort and convenience in residential spaces. TiO's offerings include lighting control and wireless audio systems that seamlessly integrate with a variety of smart home devices and well-known household brands. This enables users to manage their home environment easily through simple hardware and software products. TiO focuses on providing a user-friendly experience that fosters both enjoyment and peace of mind within the home.

LUMINELLE, developed by UVision360, offers a visual biopsy system designed for the diagnosis of uterine disorders in an office setting, minimizing the need for anesthesia. This innovative endoscopy technology streamlines hysteroscopy and cystoscopy procedures, providing a cost-effective alternative for both patients and medical practices. The system enhances convenience for physicians, patients, and staff, while also optimizing revenue for healthcare facilities. By facilitating a shift towards office-based procedures, LUMINELLE aims to improve the efficiency and accessibility of diagnostic care in gynecology.

CharlestonPharma, LLC is dedicated to developing innovative therapeutic products aimed at cancer patients and healthcare providers. The company specializes in creating fully human monoclonal antibodies that target nucleolin, a cell surface receptor associated with various cancers. With an exclusive worldwide license from the Medical University of South Carolina for eight specific antibodies and the technology to produce additional antibodies, CharlestonPharma focuses on demonstrating the preclinical efficacy and safety of its anti-nucleolin antibodies. Laboratory studies indicate that these antibodies can selectively kill cancer cells while sparing normal cells, minimizing toxicity. Additionally, the company is working on diagnostic tests that utilize cell surface nucleolin to aid in the prognosis and diagnosis of malignant diseases. CharlestonPharma operates from the Charleston Innovation Center, where its research aims to identify the most promising antibodies for future in vivo studies. The company was incorporated in 2010 and is based in Charleston, South Carolina.

Vendor Registry is a cloud-based platform designed to streamline vendor registration services for local governments. The company aims to simplify the process of doing business with state and local institutions by reducing repetitive paperwork and automating workflows that have traditionally been paper-intensive. This approach not only saves time for both vendors and government agencies but also fosters competitive bidding, enabling local businesses to generate new revenue opportunities. By centralizing the purchasing process, Vendor Registry creates a more efficient marketplace that benefits both suppliers and government entities, ultimately leading to reduced costs for taxpayer-funded purchasing departments. The platform serves as a vital link between vendors and local governments, enhancing compliance and facilitating better business practices.

KWIPPED, Inc. operates an online marketplace that specializes in B2B equipment rental and leasing. Founded in 2011 and based in Wilmington, North Carolina, the platform connects businesses with a global network of equipment suppliers, making it easier to locate and rent specialized equipment for various commercial applications. KWIPPED's technology not only streamlines the sourcing process but also aims to reduce risk and ensure quality, fostering trusted relationships between renters and suppliers. By offering a comprehensive selection of rental equipment, KWIPPED enhances accessibility for businesses seeking reliable solutions for their equipment needs.

Proterra Inc. is a manufacturer of zero-emission electric buses, primarily focused on providing sustainable transportation solutions for public and commercial transit. Founded in 2004 and headquartered in Burlingame, California, with additional offices in Greenville, South Carolina, and City of Industry, California, Proterra designs its products, including 35-foot and 40-foot electric buses, to meet the diverse needs of urban and regional transit routes. The company's Catalyst platform is noted for its modularity, allowing it to adapt to various operational demands while delivering high energy efficiency. Proterra also offers a broad range of services, including vehicle electrification solutions, fleet planning, charging infrastructure, and comprehensive vehicle maintenance programs. By facilitating the transition away from fossil fuels, Proterra aims to enhance environmental quality and reduce operational costs for fleet operators, contributing to significant reductions in greenhouse gas emissions.

Atlas Organics Inc. is a company that specializes in organics recycling, focusing on the collection and recycling of food and yard waste. Founded in 2013 and headquartered in Spartanburg, South Carolina, Atlas Organics operates in regions including San Antonio, Texas, and various areas in South Carolina, North Carolina, and Tennessee. The company partners with municipalities to collect food waste from various sources such as grocery stores, hospitals, and schools, thereby advancing sustainability initiatives. Atlas Organics transforms this waste into organic compost products suitable for agricultural, landscaping, and home gardening applications. By promoting the "table to farm" movement, Atlas Organics helps its clients achieve their sustainability goals while diverting compostable materials from landfills. The company's composting facilities produce valuable nutrients that enhance soil health, supporting both environmental and agricultural practices.

PharmRight Corporation, founded in 2013 and based in Charleston, South Carolina, focuses on designing and developing medical devices aimed at enhancing medication adherence at home. The company's flagship product, Livi, is an automated pill dispenser that helps users manage their medication schedules independently. Livi is designed to support both patients and their caregivers, simplifying the process of handling multiple medications while offering crucial assistance to caregivers. In addition to its innovative devices, PharmRight also provides a range of prescribed and non-prescribed medicines and other drugs, reinforcing its commitment to improving health outcomes through better medication management.

TARGET PharmaSolutions, Inc. specializes in providing real-world data solutions to enhance drug development and commercialization processes. Established in 2015 in Durham, North Carolina, the company focuses on creating custom datasets and analyses to address complex healthcare evidence questions. TARGET PharmaSolutions offers comprehensive health evidence solutions that aggregate real-world data from a network of participating sites, alongside bio specimen samples and consulting services. The company emerged from the success of HCV-TARGET, a model developed for Hepatitis C that has garnered significant investment and involvement from the FDA. This background has positioned TARGET PharmaSolutions to effectively support sponsors in expanding product labels and reducing the need for costly Phase IV studies.

Baebies, Inc. is a company based in Durham, North Carolina, that specializes in manufacturing screening and pediatric testing equipment for newborns. Founded in 2014 by Richard West and Vamsee Pamula, Baebies developed its newborn screening platform, SEEKER, which is FDA authorized and CE marked. SEEKER enables the simultaneous performance of multiple assays to quantitatively measure the activity of lysosomal enzymes from a single dried blood spot specimen. Additionally, the company produces the FINDER near-patient testing equipment, which also holds CE marking, and the FINDER 1.5 platform, which includes a SARS-CoV-2 test with emergency use notification from the FDA. Baebies utilizes digital microfluidics technology, allowing for efficient diagnostics from low-volume samples, and aims to enhance early disease detection for both children and adults. The company serves hospitals and public health labs, focusing on improving newborn health outcomes and providing innovative diagnostic solutions.

OBMedical Company specializes in the development, manufacture, and sale of external maternal-fetal monitoring systems designed for laboring women. The company's flagship product, the LaborView sensor system, is a wireless electrode-based device that measures labor contractions and monitors the heart rates of both mothers and infants. This innovative system allows for greater mobility during labor by providing signal capture and digital signal processing. By enhancing the accuracy and comfort of monitoring, OBMedical aims to improve health outcomes and safety for mothers and their babies during pregnancy and labor. Founded in 2012 and headquartered in Newberry, Florida, with an additional office in Norcross, Georgia, OBMedical was sold to Philips Healthcare in late 2018. The technology behind the LaborView system was developed in collaboration with the University of Florida and Convergent Engineering, making it a significant advancement in obstetric care.