Zühlke

Limula is a company that has developed an innovative platform technology designed to enhance the scalability of cell therapy production. By integrating a bioreactor and a centrifuge into a single device, Limula's solution enables healthcare providers to manufacture cell and gene therapies in a decentralized manner, bringing these treatments closer to patients. This platform, which includes hardware, software, and consumables, aims to make highly personalized and curative therapies more accessible. The automation of the production process not only increases safety and reproducibility but also allows for the large-scale manufacturing of cell therapy products, thereby addressing the critical need for improved access to gene-engineered therapies.

Bottneuro specializes in developing non-invasive therapies for patients with early to moderate-stage Alzheimer's Disease. The company utilizes its NENI technology platform to create stimulation protocols that employ electrical stimulation of neurons and glial cells in the brain. Additionally, Bottneuro's innovative brain therapy system incorporates plant-based components and features a 3D-printed cap designed for continuous monitoring and targeted delivery of active substances. This approach aims to address the specific needs of Alzheimer's patients, ultimately enhancing their quality of life and improving treatment outcomes.

Indivi is a Medical Device Software Manufacturer that is dedicated to finding solutions in clinical research and patient monitoring through innovative digital technologies. With novel, validated and patented Digital Biomarkers, we aim at measuring – with unprecedented sensitivity – changes in motor and cognitive functions in patients with neurological disorders. These novel biomarkers will establish a new standard for both pharmacological research and clinical practice.

Evismo AG, founded in 2018 and headquartered in Zurich, Switzerland, specializes in web-based remote vital signs monitoring services, particularly focusing on cardiac health. The company offers CardioFlex, an advanced online ECG service that aids healthcare professionals, including general practitioners, cardiologists, clinics, and hospitals, in diagnosing and managing conditions such as cardiac arrhythmias, sleep apnea, and stress. By providing accessible ECG data, Evismo integrates patient-centered medical care into daily life, enabling timely diagnoses and enhancing treatment options. The company's approach emphasizes cost-effective solutions that improve overall patient outcomes in diagnostics, prevention, and therapy.

Flow Neuroscience, established in 2011 and based in Malmö, Sweden, specializes in developing and manufacturing a wearable device and accompanying mobile application for medication-free treatment of depression. The company's core product is a transcranial direct current stimulation (tDCS) headset that targets the left frontal lobe, an area of the brain often associated with depression. This non-invasive treatment is complemented by a personalized mobile app that encourages users to adopt healthier daily routines, such as regular exercise and sleep patterns, to help alleviate depressive symptoms. Flow Neuroscience aims to make this innovative, affordable treatment accessible to the public, challenging the dominance of pharmaceuticals in mental health care.

Koya Medical, Inc., founded in 2018 and based in Oakland, California, specializes in developing innovative therapeutic devices aimed at treating cancer-related chronic lymphedema and various venous diseases. The company focuses on creating wearable technology that delivers active compression therapy, which is designed to enhance movement and mobility for patients. Koya Medical's approach offers a personalized alternative to traditional compression methods, utilizing a sensor-based closed-loop system to provide tailored compression patterns. This technology addresses the needs of patients suffering from conditions such as lymphedema, chronic edema, and chronic venous insufficiency, thereby improving their quality of care and overall treatment outcomes.

Lunaphore specializes in tumor analysis through innovative microfluidic chip technology, which allows for rapid and precise assays that surpass traditional methods. The company's platform facilitates the extraction of spatial proteomic and transcriptome data from tumors and other tissues, transforming standard assays into multiplex spatial biology with a user-friendly interface. This technology aids researchers in immunology, immuno-oncology, and neurology by identifying clinically relevant biomarker signatures, which support the development of diagnostic tools and streamline clinical trials. By improving the efficiency of cancer diagnostics and enhancing the accuracy of results, Lunaphore ultimately aims to contribute to better patient outcomes.

Swisstom AG, based in Landquart, Switzerland, specializes in the development and manufacturing of innovative medical devices focused on monitoring lung and heart function. Founded in 2009, the company offers advanced solutions such as the Swisstom BB2, designed for monitoring lung function in intensive care unit patients undergoing mechanical ventilation, and the elisa 800VIT, which visualizes ventilation-related complications for direct intervention. Utilizing Electrical Impedance Tomography (EIT), Swisstom's devices provide real-time, non-radiating bedside imaging that enhances patient monitoring and treatment, particularly for those facing acute respiratory distress syndrome. Their products are utilized by healthcare professionals to improve patient outcomes during critical care and anesthesia. As of July 2018, Swisstom AG operates as a subsidiary of SenTec AG.

DSwiss AG is a prominent provider of secure digital services, catering to individuals and companies globally. Founded in 2008 and headquartered in Zurich, Switzerland, the company specializes in digital vaults for personal documents and passwords, as well as secure technology for document delivery and file sharing tailored for asset managers and banking clients. DSwiss is committed to meeting high security standards for cloud solutions, which has attracted a diverse client portfolio, including numerous banks and insurance firms. The company also offers customized IT services that span project planning, implementation, and development, ensuring comprehensive solutions to meet stringent security requirements.

Distalmotion is a medical device company headquartered in Lausanne, Switzerland, focused on simplifying robotic surgery to enhance patient access to minimally invasive care in general surgery, gynecology, and urology. The company has developed a surgical robot named Dexter, which is designed and manufactured in Switzerland. Dexter merges the advantages of traditional laparoscopy with robotic capabilities, offering an innovative, on-demand approach to surgical procedures. This technology allows healthcare professionals to perform dissection and suturing in the abdominal cavity, streamlining the surgical process while maintaining affordability. Distalmotion aims to set a new standard of care by improving surgical outcomes and accessibility through its advanced robotic solutions.

Leman Micro Devices SA, founded in 2013 and based in Lausanne, Switzerland, specializes in innovative health monitoring technology for smartphones. The company has developed the V-Sensor, a pioneering miniature device that accurately measures five vital signs: blood pressure, blood oxygen (SpO2), respiration rate, pulse rate, and body temperature. This device operates without cuffs or the need for calibration, delivering results on-screen in under one minute through LMD’s e-Checkup app. Launched at CES 2021, the V-Sensor is designed to provide users with a convenient way to monitor their health using smartphones and wearable technology.

Lower back pain is one of the most common types of back pain in adults and can be debilitating. There are many different diagnoses, but the sacroiliac (SI) joint is involved in more than 15% of cases. The joint connects the hip bones to the spinal column and as a consequence experiences constant strain. Inflammation of the SI joint is correspondingly painful. In chronic cases which are not well controlled by physiotherapy and painkillers, surgical fixation of the joint remains the only option. The market for SI joint fixation is large and is growing disproportionately compared to the back orthopaedic market as a whole

Swisstom AG, based in Landquart, Switzerland, specializes in the development and manufacturing of innovative medical devices focused on monitoring lung and heart function. Founded in 2009, the company offers advanced solutions such as the Swisstom BB2, designed for monitoring lung function in intensive care unit patients undergoing mechanical ventilation, and the elisa 800VIT, which visualizes ventilation-related complications for direct intervention. Utilizing Electrical Impedance Tomography (EIT), Swisstom's devices provide real-time, non-radiating bedside imaging that enhances patient monitoring and treatment, particularly for those facing acute respiratory distress syndrome. Their products are utilized by healthcare professionals to improve patient outcomes during critical care and anesthesia. As of July 2018, Swisstom AG operates as a subsidiary of SenTec AG.